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nucleic acid, antibody, and virus culture methods to detect xenotropic mlv-related virus in human blood samples.the mlv-related retrovirus, xmrv, was recently identified and reported to be associated with both prostate cancer and chronic fatigue syndrome. at the national cancer institute-frederick, md (nci-frederick), we developed highly sensitive methods to detect xmrv nucleic acids, antibodies, and replication competent virus. analysis of xmrv-spiked samples and/or specimens from two pigtail macaques experimentally inoculated with 22rv1 cell-derived xmrv confirmed the ability of the assays used to detec ...201122312339
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