| restriction maps for the cottontail rabbit herpesvirus (cthv) genome. | the sites for restriction endonucleases apai, bamhi and pvuii in the genome of the cottontail rabbit herpesvirus were localized. the physical mapping of the 150-kb dna was facilitated by peculiarities of the genome structure, namely the presence of repetitive dna and of invertible segments, and by the analysis of overlapping cosmid clones. | 1989 | 2777085 |
| genome structure of cottontail rabbit herpesvirus. | the genome structure of a herpesvirus isolated from primary cultures of kidney cells from the cottontail rabbit sylvilagus floridanus was elucidated by using electron microscopy and restriction enzyme analysis. the genome, which was about 150 kilobase pairs long and which had an average g + c composition of 45%, consisted of two regions with unique base sequences (54 and 47 kilobase pairs) enclosed by reiterations of a 925-base-pair sequence with a variable copy number. the internal repeats were ... | 1989 | 2911115 |
| dna-binding proteins induced by the cottontail rabbit herpesvirus cthv. | several new polypeptides were detected in cells infected with cthv, a cottontail rabbit herpesvirus. all of them (mr 150k, 110k, 93k, 83k, 75k and 35k) accumulated in the nucleus during the infectious cycle, and all except the 150k species bound to dna-cellulose affinity columns in low-salt buffers. polyclonal antisera prepared against the 35k dna-binding protein also recognized the 75k species. although the 75k protein could be detected earlier in infection than the 35k protein, late in the inf ... | 1988 | 3045255 |
| cell-associated nature of cottontail rabbit herpesvirus in vitro. | the cottontail rabbit herpesvirus is presently classified in subgroup a of the herpesviruses, whereas the virus is strongly cell associated and belongs in subgroup b. | 1970 | 5462264 |
| partial characterization of two serologically related dna-binding proteins specified by the cottontail rabbit herpesvirus cthv. | we have previously described two serologically related dna-binding phosphoproteins of different apparent molecular mass (75 kda and 35 kda) produced in cottontail rabbit herpesvirus (cthv)-infected cells. the 75 kda protein appeared before the 35 kda protein in the infectious cycle. here, we extend the characterization of these proteins. protease v8 fingerprints of methionine-labelled 35 kda protein showed four major peptide products, three of which co-migrated with major peptides from digests o ... | 1995 | 7661701 |