| extract of a spice--omum (trachyspermum ammi)-shows antiaggregatory effects and alters arachidonic acid metabolism in human platelets. | an ethereal extract of omum (trachyspermum ammi; hindustani: ajwan)--a frequently consumed spice--was found to inhibit platelet aggregation induced by arachidonic acid (aa), epinephrine and collagen; in this respect it was most effective against aa-induced aggregation. inhibition of aggregation by omum could be explained by its effect on platelet thromboxane production as suggested by the following experimental observation. (i) omum reduced txb2 formation in intact platelet preparations from add ... | 1988 | 3141935 |
| fungitoxic properties of the essential oil of trachyspermum ammi sprague. | | 1986 | 3960047 |
| effect of active molluscicidal component of spices on different enzyme activities and biogenic amine levels in the nervous tissue of lymnaea acuminata. | in vivo exposure of lymnaea acuminata to thymol and [6]-gingerol (active molluscicidal components of trachyspermum ammi and zingiber officinale, respectively) indicates that they significantly alter acetylcholinesterase, lactic dehydrogenase, succinic dehydrogenase and cyto-oxidase activity in the nervous -tissue of snails. in vitro exposure showed that, except for acetylcholinesterase and lactic dehydrogenase, no significant changes were observed in cyto-oxidase and succinic dehydrogenase activ ... | 1999 | 10594932 |
| effect of different combinations of mgk-264 or piperonyl butoxide with plant-derived molluscicides on snail reproduction. | effect of sublethal treatment (20% and 60% of lc(50)/24 h) of plant-derived molluscicides, viz. polianthes tuberosa, trachyspermum ammi, allium sativum powder; azadirachta indica oil; oleoresin of zingiber officinale; and their active molluscicidal component in combination (1:5) with mgk-264 or piperonyl butoxide on the reproduction of snail lymnaea acuminata have been studied. it was observed that the combination of plant derived molluscicide and their active molluscicidal components, viz. tigo ... | 2000 | 10629280 |
| inhibitory effects of sudanese medicinal plant extracts on hepatitis c virus (hcv) protease. | one hundred fifty-two methanol and water extracts of different parts of 71 plants commonly used in sudanese traditional medicine were screened for their inhibitory effects on hepatitis c virus (hcv) protease (pr) using in vitro assay methods. thirty-four extracts showed significant inhibitory activity (>/=60% inhibition at 100 microg/ml). of these, eight extracts, methanol extracts of acacia nilotica, boswellia carterii, embelia schimperi, quercus infectoria, trachyspermum ammi and water extract ... | 2000 | 11054840 |
| preliminary screening of trachyspermum ammi (l.) seed for anthelmintic activity in sheep. | | 2006 | 17243477 |
| rapid densitometric method for simultaneous analysis of umbelliferone, psoralen, and eugenol in herbal raw materials using hptlc. | the term 'phenolics' refers to a vast array of biologically active compounds ubiquitous in plants, many of which have been used in traditional medicine for thousands of years. umbelliferone, psoralen, and eugenol are widely occurring phenolic compounds of plant origin, for which many biological activities against chronic diseases have been reported. a simple hptlc method has been developed for the simultaneous quantification of umbelliferone, psoralen, and eugenol. these three compounds were qua ... | 2007 | 17628870 |
| fumigant toxicity of essential oils from some common spices against pulse beetle, callosobruchus chinensis (coleoptera: bruchidae). | in the present study, the essential oil from seven common spices, anethum graveolens, cuminum cyminum, illicium verum, myristica fragrans, nigella sativa, piper nigrum and trachyspermum ammi was isolated and its insecticidal, oviposition, egg hatching and developmental inhibitory activities were determined against pulse beetle, callosobruchus chinensis. essential oils were isolated by hydrodistillation method using clevenger apparatus. these essential oils caused death of adults and larvae of ca ... | 2008 | 18270466 |
| antifilarial lead molecules isolated from trachyspermum ammi. | lymphatic filariasis is caused by infection with the parasitic filarial nematodes wuchereria bancrofti, brugia malayi and b. timori, transmitted by mosquitoes. the lack of an adulticidal drug poses a challenge to filariasis elimination, hence it is essential to develop an effective antifilarial drug which could either kill or permanently sterilize the adult worms. in the reported work the in vitro activity of a methanolic extract of fruits of trachyspermum ammi (apiaceae) against adult bovine fi ... | 2008 | 18830147 |
| purification and characterization of an anticalcifying protein from the seeds of trachyspermum ammi (l.). | till date various plants extract have been studied to reduce the incidence of urolithiasis but the identification of naturally occurring calcium oxalate (caox) inhibitory biomolecules from plants was hampered in past by limitation in identification method. the present study is aimed at examining the efficacy of trachyspermum ammi on caox crystallization in vitro and further by combining conventional biochemical methods with recent advances in mass spectrometry, a novel calcium oxalate (caox) cry ... | 2009 | 19200041 |
| nematicidal activity of plant essential oils and components from ajowan (trachyspermum ammi), allspice (pimenta dioica) and litsea (litsea cubeba) essential oils against pine wood nematode (bursaphelenchus xylophilus). | commercial plant essential oils from 26 plant species were tested for their nematicidal activities against the pinewood nematode, bursaphelenchus xylophilus. good nematicidal activity against b. xylophilus was achieved with essential oils of ajowan (trachyspermum ammi), allspice (pimenta dioica) and litsea (litsea cubeba). analysis by gas chromatography-mass spectrometry led to identification of 12, 6 and 16 major compounds from ajowan, allspice and litsea oils, respectively. these compounds fro ... | 2007 | 19259498 |
| insecticidal and repellent activities of thymol from the essential oil of trachyspermum ammi (linn) sprague seeds against anopheles stephensi. | essential oil of seeds of trachyspermum ammi (linn.) sprauge and its pure constituent thymol showed promising results when evaluated for larvicidal, oviposition-deterrent, vapor toxicity, and repellent activity against malarial vector, anopheles stephensi. thymol was 1.6-fold more toxic than the oil toward fourth-instar larvae of a. stephensi with ld(50) values of 48.88 and 80.77 microg/ml, respectively. egg laying by female adults of a. stephensi was much significantly reduced when exposed to v ... | 2009 | 19343365 |
| comparison of bacteriostatic and bactericidal activity of 13 essential oils against strains with varying sensitivity to antibiotics. | to compare the bacteriostatic and bactericidal activity of 13 chemotyped essential oils (eo) on 65 bacteria with varying sensitivity to antibiotics. | 2008 | 19552780 |
| antibacterial and phytochemical screening of anethum graveolens, foeniculum vulgare and trachyspermum ammi. | anethum graveolens linn., foeniculum vulgare mill. and trachyspermum ammi l. are widely used traditional medicinal plants to treat various ailments. to provide a scientific basis to traditional uses of these plants, their aqueous and organic seed extracts, as well as isolated phytoconstituents were evaluated for their antibacterial potential. | 2009 | 19656417 |
| fumigant antitermitic activity of plant essential oils and components from ajowan ( trachyspermum ammi ), allspice ( pimenta dioica ), caraway ( carum carvi ), dill ( anethum graveolens ), geranium ( pelargonium graveolens ), and litsea ( litsea cubeba ) oils against japanese termite ( reticulitermes speratus kolbe). | plant essential oils from 26 plant species were tested for their insecticidal activities against the japanese termite, reticulitermes speratus kolbe, using a fumigation bioassay. responses varied with source, exposure time, and concentration. among the essential oils tested, strong insecticidal activity was observed with the essential oils of ajowan ( trachyspermum ammi ), allspice ( pimenta dioica ), caraway ( carum carvi ), dill ( anethum graveolens ), geranium ( pelargonium graveolens ), and ... | 2009 | 19722567 |
| in vivo efficacy of trachyspermum ammi anticalcifying protein in urolithiatic rat model. | many medicinal plants have been employed during ages to treat urinary stones though the rationale behind their use is not well established. recently, we have successfully purified an anticalcifying protein from the seeds of trachyspermum ammi (l.) sprague ex turril (umbelliferae) using oxalate depletion assay and deciphered its inhibitory activity against calcium oxalate crystal growth. | 2009 | 19781619 |
| chemomodulatory effect of trachyspermum ammi on murine skin and forestomach papillomagenesis. | trachyspermum ammi seed consumed worldwide as a spice ingredient is much valued for its medicinal properties. however, it has not been investigated for its cancer chemopreventive efficacy. herein, the chemopreventive effect of different doses (2%, 4%, and 6%) of test diets of trachyspermum ammi seeds were examined on dmba-induced skin and b(a)p-induced forestomach papillomagenesis, inducibility of drug metabolizing phase i and phase ii enzymes, antioxidant enzymes(catalase, superoxide dismutase, ... | 2010 | 20043262 |
| activity of solvent extracts of prosopis spicigera, zingiber officinale and trachyspermum ammi against multidrug resistant bacterial and fungal strains. | the emerging trends of multidrug resistance among several groups of microorganisms against different classes of antibiotics led different researchers to develop efficient drugs from plant sources to counter multidrug resistant strains. this study investigated different solvent extracts of prosopis spicigera (p. spicigera), zingiber officinale, and trachyspermum ammi (t. ammi) to determine their efficacy against multidrug resistant microbes. | 2010 | 20539061 |
| novel compound from trachyspermum ammi (ajowan caraway) seeds with antibiofilm and antiadherence activities against streptococcus mutans: a potential chemotherapeutic agent against dental caries. | the objective of this study was to isolate and characterize the active compound from trachyspermum ammi seeds, exhibiting antibiofilm activity against streptococcus mutans, a major causal organism of dental caries. | 2010 | 20846336 |
| in vitro determination of the contraceptive spermicidal activity of essential oil of trachyspermum ammi (l.) sprague ex turrill fruits. | this study was conducted to determine the spermicidal and contraceptive efficacy of essential oil of trachyspermum ammi on human sperm in vitro. chemical compositions of the oil were analyzed by gc-ms. nearly 30 compounds representing 91.39% of the total oil were identified. the minimum effective dose (med) of essential oil of t. ammi that induced instant immobilization of human spermatozoa in vitro was 125++g/ml. the motility was also irreversible. all of the human sperms were found to be non v ... | 2011 | 21396489 |
| studies on the viability and membrane integrity of human spermatozoa treated with essential oil of trachyspermum ammi (l.) sprague ex turrill fruit. | the present study aimed at investigating the effects of essential oil of trachyspermum ammi fruits, an oil-bearing plant of apiaceae family, on human sperm viability and membrane integrity. chemical compositions of the oil were analysed by gc-ms. thirty compounds representing 91.39% of the total oil were identified. the viability and membrane integrity of human spermatozoa were assessed using minimum effective dose (med) concentration (125ôçâ╬╝gôçâml(-1) ) of the oil. sperm treated with essentia ... | 2011 | 21671979 |
| anticoccidial activity of herbal complex in broiler chickens challenged with eimeria tenella. | summarythe objective of the present study was to evaluate the anticoccidial effect of different concentrations of the herbal complex of 4 plants (leaves of azadirachta indica and nicotiana tabacum, flowers of calotropis procera and seeds of trachyspermum ammi) in broiler chickens in comparison with amprolium anticoccidial. three concentrations (2 g, 4 g and 6 g) of herbal complex were given to the experimental groups once a day and amprolium (at the dose rate of 125 ppm) was given orally in drin ... | 2011 | 22018334 |
| larvicidal and repellent activity of medicinal plant extracts from eastern ghats of south india against malaria and filariasis vectors. | to evaluate the larvicidal and repellent activities of ethyl acetate and methanol extracts of acacia concinna (a. concinna), cassia siamea (c. siamea), coriandrum sativum (c. sativum),cuminum cyminum (c. cyminum), lantana camara (l. camara), nelumbo nucifera (n. nucifera) phyllanthus amarus (p. amarus), piper nigrum (p. nigrum) and trachyspermum ammi (t. ammi) against anopheles stephensi (an. stephensi) and culex quinquefasciatus (cx. quinquefasciatus). | 2011 | 21967692 |
| in vitro and in vivo acaricidal activity of a herbal extract. | the anti-tick efficacy of combined aqueous herbal extracts of azadirachta indica leaves, nicotiana tabacum leaves, calotropis procera flowers and trachyspermum ammi seeds was evaluated using adult immersion test, larval packet test and ear bag method. the extract exhibited lethal effects on egg laying (index of egg laying=0.371404±0.00435), hatching (22.35%) and total larval mortality at 50 mg ml(-1) and reduced tick intensity on the infested calves (18 detached out of 35 at 45% (w/w) suspension ... | 2011 | 22305296 |
| in vitro lethal effect of ajowan (trachyspermum ammi l.) essential oil on hydatid cyst protoscoleces. | various chemical scolicidal agents have been used for inactivation of hydatid cyst protoscolices, but most of them are associated with adverse side effects. since ajowan (trachyspermum ammi) has been shown to have a number of medicinal properties, in this study the scolicidal effect of the essential oil (eo) from the fruits of this herbal plant was investigated. ajowan eo was obtained by hydrodistillation method. gas chromatography (gc) and gas chromatography-mass spectrometry (gc-ms) were emplo ... | 2011 | 22245070 |
| isolation and identification of salmonella from curry samples and its sensitivity to commercial antibiotics and aqueous extracts of camelia sinensis (l.) and trachyspermum ammi (l.). | to isolate salmonella from curry samples and to evaluate the drug sensitivity of the food-borne salmonella and its susceptibility to specific plant extracts. | 2011 | 23569772 |