| comparative evaluation of hypoglycaemic activity of some indian medicinal plants in alloxan diabetic rats. | in our experiments 30 hypoglycaemic medicinal plants (known and less known) have been selected for thorough studies from indigenous folk medicines, ayurvedic, unani and siddha systems of medicines. in all the experiments with different herbal samples (vacuum dried 95% ethanolic extracts), definite blood glucose lowering effect within 2 weeks have been confirmed in alloxan diabetic albino rats. blood glucose values are brought down close to normal fasting level using herbal samples at a dose of 2 ... | 2003 | 12499084 |
| hepatoprotective effect of trichosanthes cucumerina var cucumerina l. on carbon tetrachloride induced liver damage in rats. | different parts of the plant trichosanthes cucumerina var cucumerina l. (cucurbitaceae) are used to treat liver disorders, traditionally. it is one among the constituents in various ayurvedic formulations used for the treatment of liver disorders and other diseases. | 2009 | 19429383 |
| antiproliferative effects of cucurbitacin b in breast cancer cells: down-regulation of the c-myc/htert/telomerase pathway and obstruction of the cell cycle. | naturally occurring cucurbitacins have been shown to have anticancer, antimicrobial and anti-inflammatory activities. in this study, we determined the effects of cucurbitacin b extracted from the thai herb trichosanthes cucumerina l. on telomerase regulation in three human breast cancer cell lines (t47d, skbr-3, and mcf-7) and a mammary epithelium cell line (hbl-100). cell viability after treatment with cucurbitacin b, which is an active ingredient of this herb, was assessed. telomeric repeat am ... | 2010 | 21614210 |
| in vitro and in vivo evaluation of antioxidant activity of trichosanthes cucumerina aerial parts. | the present study was conducted to determine whether aerial parts of trichosanthes cucumerina extracts can exert significant antioxidant activity. the antioxidant activity of a hot water extract (hwe) and a cold ethanolic extract (ce) of t. cucumerina aerial parts was evaluated by assessing its (a) radical scavenging ability and prevention effect of lipid peroxidation in vitro, and (b) effects on lipid peroxidation and antioxidant enzyme activities, in vivo.in vitro antioxidant assays (dpph, tba ... | 2011 | 21840826 |
| anti-inflammatory activity of trichosanthes cucumerina linn. in rats. | trichosanthes cucumerina linn. (family: cucurbitaceae) is one of the medicinal plants that is often used in sri lankan traditional systems of medicine. one of its uses is the treatment of inflammatory conditions. however, validity of the anti-inflammatory activity has not been scientifically investigated so far. therefore, the aim of this study was to investigate the anti-inflammatory potential of trichosanthes cucumerina hot water extract (hwe) and its fractions. | 2010 | 20654707 |
| trichosanthes cucumerina linn. improves glucose tolerance and tissue glycogen in non insulin dependent diabetes mellitus induced rats. | to study the effect of trichosanthes cucumerina linn. on non insulin dependent diabetes mellitus induced rats. | 2008 | 20040935 |
| gastroprotective activity of trichosanthes cucumerina in rats. | the aim of the present study was to scientifically investigate whether trichosanthes cucumerina linn (family: cucurbitaceae) has gastroprotective activity. | 2010 | 19963056 |
| cytotoxic properties of root extract and fruit juice of trichosanthes cucumerina. | the root extract of trichosanthes cucumerina l. and bryonolic acid (1), its main constituent, as well as the fruit juice and cucurbitacin b (3), its main constituent, were tested for cytotoxicity against four human breast cancer cell lines (skbr3, mcf7, t47d, and mda-mb435), two lung cancer cell lines (a549 and sk-lu1), and one colon cancer cell line (caco-2). the root extract had higher ic (50) values than bryonolic acid (1) against three breast cancer cell lines (mcf7 = 267/121, t47d = 316/124 ... | 2009 | 19288406 |
| sri lankan rice mixed meals: effect on glycaemic index and contribution to daily dietary fibre requirement. | the glycaemic index (gi) concept ranks starchy foods according to the blood glucose responses following ingestion. when considering commonly consumed sri lankan meals, only a few can be categorised as low gi. however, a significant negative correlation between the gi of sri lankan meals and fibre content has been observed indicating the potential to reduce the gi of meals by incorporating naturally occurring sources of fibre. thus, the objective of this study was to study the effect of increased ... | 2011 | 22135869 |
| taxonomic significance of trichomes micromorphology in cucurbits. | studies on trichomes micromorphology using scanning electron microscope (sem) were undertaken in 23 species with one variety under 13 genera of the family cucurbitaceae (viz., benincasa hispida (thunb.) cogn., citrullus lanatus (thunb.) matsum. & nakai, cucumis melo var. agrestis naudin, cucumis sativus l., diplocyclos palmatus (l.) c. jeffrey, edgaria dargeelingensis c.b. clarke, gynostemma burmanicum king ex chakr., gynostemma pentaphyllum (thunb.) makino, gynostemma pubescens (gagnep.) c.y. w ... | 2011 | 23961108 |
| the treatment of jaundice with medicinal plants in indigenous communities of the sub-himalayan region of uttarakhand, india. | inspite of tremendous advances made in allopathic medical practices, herbs still play an important role in the management of various liver diseases. a large number of plants and formulations have been claimed to have hepatoprotective activity. jaundice is a symptom, indicative of the malfunctioning of the liver. this paper provides ethnomedicinal information on the plants used to treat jaundice by three important indigenous communities, i.e., nomadic gujjars, tharu and bhoxa of sub-himalayan reg ... | 2012 | 22759701 |
| chemical and antioxidant properties of snake tomato (trichosanthes cucumerina) juice and pineapple (ananas comosus) juice blends and their changes during storage. | juice blends made from the mixture of snake tomato (trichosanthes cucumerina) and pineapple (ananas comosus) fruits were analyzed for ph, antioxidant properties, total titratable acidity, vitamin c, lycopene and total phenolic contents after different blend ratios were made. the addition of snake tomato juice increased the vitamin c, total carotene, lycopene and antioxidant properties of the juice blends. the radical scavenging properties of juice blends containing a higher ratio of snake tomato ... | 2017 | 27855888 |