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gibberellin a4 produced by sphaceloma manihoticola, the cause of the superelongation disease of cassava (manihot esculenta). 1979518631
the isoprenoid pathway: cloning and characterization of fungal fpps genes.farnesylpyrophosphate synthase (fpps) is a key enzyme in isoprenoid biosynthesis. several classes of essential metabolites, including sterols, quinones, carotenoids and gibberellins, are terpenoids with high biological activity. the structural gene for fpp synthase was isolated from two ascomycete fungi, neurospora crassa and gibberella fujikuroi. a comparative analysis of the nucleotide sequences of both fpps genes revealed the presence of introns at the same positions at the 5' end of the codi ...19968753652
3-hydroxy-3-methylglutaryl-coa reductase gene of gibberella fujikuroi: isolation and characterization.3-hydroxy-3-methylglutaryl-coa reductase (hmgr) is the first specific enzyme of the isoprenoid pathway, which leads to several classes of primary and secondary metabolites such as sterols, quinones, carotenoids and gibberellins. the structural gene of hmg-coa reductase was isolated from the ascomycetous fungus gibberella fujikuroi. additionally, the most conserved region of this gene was also isolated from another plant pathogenic fungus, sphaceloma manihoticola. both ascomycetous fungi use the ...19979000379
inhibition of gibberellin production in the fungi gibberella fujikuroi and sphaceloma manihoticola by plant growth retardants.the effect of different types of plant growth retardants on fungal gibberellin (ga) formation has been studied in cultures of gibberella fujikuroi and sphaceloma manihoticola. quaternary ammonium compounds (chlormequat chloride, mepiquat chloride, amo-1618), triazoles (uniconazole and several experimental compounds), and the norbornanodiazetine tetcyclacis inhibited ga biosynthesis in both fungal species. concentrations between 2 x 10(-4) and 10(-9)m were required for a 50% inhibition of the pro ...199216653038
isolation and characterization of the gibberellin biosynthetic gene cluster in sphaceloma manihoticola.gibberellins (gas) are tetracyclic diterpenoid phytohormones that were first identified as secondary metabolites of the fungus fusarium fujikuroi (teleomorph, gibberella fujikuroi). gas were also found in the cassava pathogen sphaceloma manihoticola, but the spectrum of gas differed from that in f. fujikuroi. in contrast to f. fujikuroi, the ga biosynthetic pathway has not been studied in detail in s. manihoticola, and none of the ga biosynthetic genes have been cloned from the species. here, we ...200818567680
diversity, regulation, and evolution of the gibberellin biosynthetic pathway in fungi compared to plants and bacteria.bioactive gibberellins (gas) are diterpene plant hormones that are biosynthesized through complex pathways and control diverse aspects of growth and development. gas were first isolated as metabolites of a fungal rice pathogen, gibberella fujikuroi, since renamed fusarium fujikuroi. although higher plants and the fungus produce structurally identical gas, significant differences in their ga pathways, enzymes involved and gene regulation became apparent with the identification of ga biosynthetic ...200919560174
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