| alpha-adrenoceptors and monoamine contents in the cerebral cortex of the rodent jaculus orientalis: effects of acute cold exposure. | the tritiated adrenergic antagonists prazosin ([3h]prz) and idazoxan ([3h]ida, or rx-781094) bind specifically and with high affinity to alpha 1- and alpha 2-adrenoceptors respectively, and were used to measure adrenoceptors in membrane preparations obtained from the cerebral cortex of jaculus orientalis. membrane preparations were also obtained from a group of cold exposed animals, to determine whether these adrenoceptors could be modified by a thermic stress. the density of receptors (bmax; ma ... | 1986 | 3024182 |
| renal excretion capacity in hydrated desert rodents (jaculus orientalis and jaculus deserti). | the capacity to excrete a water load was studied in rats and in two desert rodents (jaculus orientalis and jaculus deserti) adapted to either 5 or 30 degrees c ambient temperature. the rat is able to eliminate the entire water load regardless of thermal adaptation. cold-adapted j. orientalis and j. deserti excreted 60% of the water load in comparison to 20-30% in warm-adapted jerboas. at both adaptation temperatures, antidiuretic hormone (adh) concentration was estimated at maximum diuresis in t ... | 1987 | 3571573 |
| plasma antidiuretic hormone levels and liver vasopressin receptors in the jerboa, jaculus orientalis, and rat. | v1 vasopressin, angiotensin, alpha-adrenergic, and glucagon receptors in liver were studied on membrane fractions prepared from two groups of jerboas ( jaculus orientalis) given dry or water-enriched diets for periods of 4 to 7 weeks, and from rats acutely treated with pharmacological amounts of arginine-vasopressin (avp) or (1-deamino-8-d-arginine)-vasopressin (ddavp). tritiated (8-lysine)-vasopressin ([3h]vasopressin), tritiated (1-asparagine-5-valine)-angiotensin ii ([3h]angiotensin ii), trit ... | 1984 | 6329898 |
| plasma antidiuretic hormone levels and kidney responsiveness to vasopressin in the jerboa, jaculus orientalis. | the plasma antidiuretic hormone (adh) concentration and the kidney medulla responsiveness to vasopressin were measured in adult jerboas ( jaculus orientalis) in different states of hydration. in 15 jerboas adapted to 30 degrees and fed a dry diet, the average adh concentration in blood plasma was 479 +/- 59 pg/ml, as measured by a radioimmunoassay. about 6 hr after receiving a 5% body wt water load by gavage, the plasma adh concentration fell to 130 +/- 30 pg/ml in the 5 jerboas still producing ... | 1984 | 6735146 |
| [measurement of antidiuretic hormone and plasma renin activity in desert rodents]. | plasma antidiuretic hormone (adh) and renin activity (pra) were determined in two species of desert rodent (jaculus orientalis and jaculus deserti) under chronic dehydration and were compared to those of wistar rat. adh concentration was very high in the desert animals: 200 times higher than in the rat on a normal diet and 20 times higher than in the 48 hours-dehydrated rats. the neurohypophyseal adh content of these rodents was twice that of the normally hydrates rat, while the dehydration caus ... | 1981 | 6791780 |
| synthesis, turnover, and release of peptides from the neurohypophysis of the jerboa jaculus orientalis. | peptide contents of neural lobes from adult jerboas (jaculus orientalis) under different states of hydration were determined by radioimmunoassay. the amounts of vasopressin, oxytocin, and their associated neurophysins in animals dehydrated for up to 4 weeks were not significantly different from those of controls. the different neurohypophyseal peptide were separated on two different types of gradient using reverse-phase high-performance liquid chromatography. the shape of the chromatograms sugge ... | 1994 | 8194737 |
| mapping of [3h]vasopressin binding sites in the brain of jerboa (jaculus orientalis) by an high resolution beta-radio imager. | the distribution of vasopressin receptors in the brain of the jerboa (jaculus orientalis) was studied using tritiated arginin vasopressin ([3h]vasopressin). beta-particles emitted from tritiated ligand bound to brain sections were detected by a newly developed beta-radio imager to generate a light spot which was read by a charge coupled device camera. the number and coordinate of the center of gravity of the light spot were recorded. after summation in pixels of the counts collected during 2-20 ... | 1993 | 8271842 |
| properties of peroxisomes from jerboa (jaculus orientalis). | this report presents new data on mammalian peroxisomes by studying an unusual rodent: the jerboa (jaculus orientalis). this animal exhibits some unique peroxisomal properties compared to the rat, such as higher cyanide-insensitive palmitoyl-coa oxidase specific activity, pattern differences in sds-page peroxisomal proteins as well as in acyl-coa oxidase immunoblotting. there is also a peculiar response to a peroxisome proliferator, ciprofibrate. with 250 ppm of ciprofibrate in the diet for 2 wee ... | 1996 | 8793387 |
| occurrence of a differential expression of the glyceraldehyde-3-phosphate dehydrogenase gene in muscle and liver from euthermic and induced hibernating jerboa (jaculus orientalis). | a cdna clone which contains the near-complete open reading frame (orf) encoding glyceraldehyde-3-phosphate dehydrogenase (gapdh, ec 1.2.1.12) was obtained by screening a muscle cdna library of jerboa (jaculus orientalis), a true hibernating rodent, with a pcr-amplified 0.5-kb genomic dna probe from an internal region of the gene. the 1.1-kb cdna clone consists of a 927-bp orf which codifies for 309 aa, about 93% of the original gapc gene encoding the 36-kda protein, and a 3'-noncoding region of ... | 1996 | 8973322 |
| cold- and ouabain-resistance of renal na,k-atpase in cold-exposed and hibernating jerboas (jaculus orientalis). | the temperature dependence and the ouabain sensitivity of na,k-atpase was examined in the nephron of normal, cold-exposed, and hibernating jerboas. the transport and hydrolytic activity of renal na,k-atpase displayed similar temperature dependence in rats and normal jerboas. cold-resistance of na,k-atpase appeared in cold-exposed jerboas and further increased during hibernation. three subpopulations of na,k-atpase displaying very high (ki approximately 10(-13) m), high (ki approximately 10(-9) m ... | 1997 | 9219354 |
| safety evaluation of the sag2 rabies virus mutant in tunisian dogs and several non-target species. | the safety of the sag2 rabies virus, a highly attenuated mutant of the sad strain intended to vaccinate dogs by the oral route, was evaluated in local tunisian dogs and in five other local species likely to consume vaccine baits. these species were the domestic cat (felis catus), the jackal (canis aureus), the jerboa (jaculus orientalis), the merion (meriones sp.) and the gerbil (gerbillus campestris). the vaccine was administered orally to 21 dogs, 11 cats and eight jackals and orally or intram ... | 1999 | 10478416 |
| effect of hibernation, thyroid hormones and dexamethasone on cytosolic and mitochondrial glycerol-3-phosphate dehydrogenase from jerboa (jaculus orientalis). | tissue distribution of the cytosolic and mitochondrial glycerol-3-phosphate dehydrogenase (cgpdh and mgpdh) activities in jerboa (jaculus orientalis), a hibernator, shows the highest level of enzyme activity in skeletal muscle and brown adipose tissue, respectively. the effect of hibernation on cgpdh indicates an increase of activity in all tissues examined. in contrast, hibernation decreases mgpdh activity in all tissues, except skeletal muscle. the effect of thyroid hormones on gpdh activity w ... | 2000 | 10904857 |
| the gonadotropin-releasing hormone neurosecretory system of the jerboa (jaculus orientalis) and its seasonal variations. | the distribution of cells expressing gonadotropin-releasing hormone (gnrh) immunoreactivity was examined in the brain of adult jerboa during two distinct periods of the reproductive cycle. during spring-summer, when the jerboa is sexually active, a high density of cell bodies and fibres immunoreactive (ir) for gnrh was observed at the level of separation of the frontal lobes, in the medial septal nucleus (ms) and in the diagonal band of broca (dbb), in the preoptic area (poa), in the organum vas ... | 2000 | 11106979 |
| biochemical characterisation and immunohistochemical localisation of the secretogranin ii-derived peptide em66 in the hypothalamus of the jerboa (jaculus orientalis): modulation by food deprivation. | the neuroendocrine protein secretogranin ii is the precursor of several neuropeptides, including secretoneurin and a novel 66-amino acid peptide, em66, the sequence of which has been highly conserved across the vertebrae phylum. the presence of em66 has been detected in the adult and fetal human adrenal gland, as well as the rat pituitary and adrenal glands. the present study aimed to explore a possible neuroendocrine role of em66 by analysing its occurrence and distribution within the jerboa hy ... | 2005 | 15929742 |
| immunocytochemical detection of cholecystokinin and corticotrophin-releasing hormone neuropeptides in the hypothalamic paraventricular nucleus of the jerboa (jaculus orientalis): modulation by immobilisation stress. | the hypothalamic response to an environmental stress implicates the corticotrophin-releasing hormone (crh) neuroendocrine system of the hypothalamic parvicellular paraventricular nucleus (pvn) in addition to other neuropeptides coexpressed within crh neurones and controlling the hypothalamo-pituitary-adrenal (hpa) axis activity as well. such neuropeptides are vasopressin, neurotensin and cholecystokinin (cck). it has previously been demonstrated that the majority of the crh neuronal population c ... | 2006 | 16965295 |
| immunohistochemical distribution of the secretogranin ii-derived peptide em66 in the rat hypothalamus: a comparative study with jerboa. | em66 is a 66-amino acid peptide derived from secretogranin ii, a member of granin acidic secretory protein family, by proteolytic processing. em66 has been previously characterized in the jerboa (jaculus orientalis) hypothalamus and its potential implication in the neuroendocrine regulation of feeding behaviour has been demonstrated. in the present study, an immunohistochemical analysis of the localization of em66 within hypothalamic structures of rat was performed and compared to the distributi ... | 2007 | 17240057 |
| prehibernation and hibernation effects on the d-3-hydroxybutyrate dehydrogenase of the heavy and light mitochondria from liver jerboa (jaculus orientalis) and related metabolism. | the d-3-hydroxybutyrate dehydrogenase (bdh) (ec 1.1.1.30) from liver jerboa (jaculus orientalis), a ketone body converting enzyme in mitochondria, in two populations of mitochondria (heavy and light) has been studied in different jerboa states (euthermic, prehibernating and hibernating). the results reveal: (1) important variations between states in terms of ketones bodies, glucose and lipid levels; (2) significant differences between the bdh of the two mitochondrial populations in term of prote ... | 2007 | 17531367 |
| immunoaffinity purification and characterization of mitochondrial membrane-bound d-3-hydroxybutyrate dehydrogenase from jaculus orientalis. | the interconversion of two important energy metabolites, 3-hydroxybutyrate and acetoacetate (the major ketone bodies), is catalyzed by d-3-hydroxybutyrate dehydrogenase (bdh1: ec 1.1.1.30), a nad+-dependent enzyme. the eukaryotic enzyme is bound to the mitochondrial inner membrane and harbors a unique lecithin-dependent activity. here, we report an advanced purification method of the mammalian bdh applied to the liver enzyme from jerboa (jaculus orientalis), a hibernating rodent adapted to extre ... | 2008 | 18826626 |
| differential regulation of peroxisome proliferator-activated receptor (ppar)-alpha1 and truncated pparalpha2 as an adaptive response to fasting in the control of hepatic peroxisomal fatty acid beta-oxidation in the hibernating mammal. | seasonal obesity and fasting-associated hibernation are the two major metabolic events governing hepatic lipid metabolism in hibernating mammals. in this process, however, the role of the nuclear receptor known as peroxisome proliferator-activated receptor (ppar)-alpha has not been elucidated yet. here we show, as in human, that jerboa (jaculus orientalis) liver expresses both active wild-type pparalpha (pparalpha1wt) and truncated pparalpha forms and that the pparalpha1wt to truncated pparalpha ... | 2009 | 18948393 |
| sensitivity of liver metabolism in jerboa (jaculus orientalis) to ciprofibrate, a peroxisome proliferator. | ciprofibrate is a well-known drug used to normalize lipid parameters and fibrinogen in atherosclerosis patients. in laboratory rodents such as rats or mice, ciprofibrate exhibits peroxisome proliferator activity. however, to date, no clear alterations or side effects caused by ciprofibrate have been noted in humans. in order to further investigate such possible relationships, we studied the effects of sustained ciprofibrate treatment in jerboas (jaculus orientalis). in these rodents, ciprofibrat ... | 2009 | 21475872 |
| [secretion of antidiuretic hormone and renal function during the awakening of jaculus orientalis from hibernation]. | chemical analysis of kidney tissue from jerboa (jaculus orientalis) during hibernation shows that the cortico-papillary gradient of na+ ions is strongly reduced, whereas that of urea is completely suppressed. during the spontaneous rise in body temperature which occurs as the animal comes out of hibernation, the accumulation of na+ in the papilla then in the medullary zones begins to increase from 25-30 degrees c body temperature, before the appearance of a urea gradient. this confirms the hypot ... | 2013 | 3795117 |
| bartonella jaculi sp. nov., bartonella callosciuri sp. nov., bartonella pachyuromydis sp. nov. and bartonella acomydis sp. nov., isolated from wild rodentia. | four novel strains of members of the genus bartonella, oy2-1(t), br11-1(t), fn15-2(t) and ks2-1(t), were isolated from the blood of wild-captured greater egyptian jerboa (jaculus orientalis), plantain squirrel (callosciurus notatus), fat-tailed gerbil (pachyuromys duprasi) and golden spiny mouse (acomys russatus). all the animals were imported to japan as pets from egypt, thailand and the netherlands. the phenotypic characterization (growth conditions, incubation periods, biochemical properties ... | 2013 | 22941296 |
| c-banding karyotype and relationship of the dipodids allactaga and jaculus (mammalia: rodentia) in egypt. | the c-banding karyotype of the jerboas allactaga tetradactyla, jaculus jaculus jaculus, and jaculus orientalis was described and interspecific relationships were discussed. despite the conservation of a relatively small amount of c-heterochromatin located at the centromeric region of some chromosomes in all karyotypes, a striking loss of c-heterochromatin was clearly observed in j. orientalis. c-bands were totally absent in 33 of the 48 chromosomes of j. orientalis, compared to only 7 for j.j.ja ... | 2004 | 15521644 |
| a comparative analysis of the rate of meiosis, chiasma frequency and terminalization in the jerboas allactaga and jaculus (rodentia: dipodidae) in egypt. | the rate of seven meiotic stages (zygotene-pachytene, diplotene-diakinesis, metaphase i, anaphase i, metaphase ii, anaphase ii, and quartet) was studied in the jerboas jaculus jaculus jaculus, jaculus orientalis, and allactaga tetradactyla, chiasma frequency and terminalization being examined only in j. jaculus and j. orientalis, and compared with the previous data concerning a. tetradactyla. significant differences in the rate of meiosis, frequency of bivalent types, and frequency of interstiti ... | 2001 | 11987448 |
| molecular assessment of hepatozoon (apicomplexa: adeleorina) infections in wild canids and rodents from north africa, with implications for transmission dynamics across taxonomic groups. | parasites play a major role in ecosystems, and understanding of host-parasite interactions is important for predicting parasite transmission dynamics and epidemiology. however, there is still a lack of knowledge about the distribution, diversity, and impact of parasites in wildlife, especially from remote areas. hepatozoon is a genus of apicomplexan parasites that is transmitted by ingestion of infected arthropod vectors. however, alternative modes of transmission have been identified such as tr ... | 2014 | 25050803 |
| postnatal development of body architecture and gait in several rodent species. | observations on five species of rodents, vole (microtus socialis), gerbil (gerbillus dasyurus), jird (meriones tristrami), dormouse (eliomys melanurus) and jerboa (jaculus orientalis), revealed that, during the period when their neonates share a matching morphology, they also share the same forms of quadruped locomotion (gaits). the order in which the different gaits develop is similar in all species, beginning with the basic gaits of lateral walk and trot. gaits and body morphology do not under ... | 1997 | 9172418 |
| karyotypic variation in two species of jerboas jaculus jaculus and jaculus orientalis (rodentia, dipodidae) from tunisia. | the karyotypes of the lesser egyptian jerboa jaculus jaculus and the greater egyptian jerboa jaculus orientalis from tunisia are described and compared with available data particularly from egypt. the species examined have a similar karyotype consisting of 2n = 48 chromosomes and a fundamental number of autosomes (nfa) varying from 88 to 90 in j. jaculus and from 84 to 88 in j. orientalis. the x chromosome is submetacentric in both species, while the y is submetacentric in j. orientalis and acro ... | 2010 | 20968190 |
| coordinated seasonal regulation of metabolic and reproductive hypothalamic peptides in the desert jerboa. | jerboa (jaculus orientalis) is a semi-desert rodent displaying strong seasonal variations in biological functions in order to survive harsh conditions. when environmental conditions become unfavorable in early autumn, it shuts down its reproductive axis, increases its body weight, and finally hibernates. in spring, the jerboa displays opposite regulations, with a reactivation of reproduction and reduction in body weight. this study investigated how genes coding for different hypothalamic peptide ... | 2016 | 27113425 |
| overwinter body temperature patterns in captive jerboas (jaculus orientalis): influence of sex and group. | the jerboa (jaculus orientalis) has been described in the past as a hibernator, but no reliable data exist on the daily and seasonal rhythmicity of body temperature (t (b)). in this study, t (b) patterns were determined in different groups of jerboas (isolated males and females, castrated males and grouped animals) maintained in captivity during autumn and winter, and submitted to natural variations of light and ambient temperature (t (a)). t (b) and t (a) variations were recorded with surgicall ... | 2011 | 20981552 |
| phase and period responses of the jerboa jaculus orientalis to short light pulses. | the phase and period responses to short light pulses were studied in the jerboa, a seasonal, hibernating, nocturnal rodent from the atlas region in morocco. the jerboa, which is a saltatory species, showed precise activity onsets and offsets under a light-dark (ld) cycle using infrared captors to record locomotor activity. when released into constant darkness (dd), the majority of animals showed a circadian period (tau) < 24 h (mean tau = 23.89 +/- 0.13 h) and a lengthening of the activity span, ... | 2010 | 20795880 |
| characterization of two d-beta-hydroxybutyrate dehydrogenase populations in heavy and light mitochondria from jerboa (jaculus orientalis) liver. | mitochondrial membrane-bound and phospholipid-dependent d-beta-hydroxybutyrate dehydrogenase (bdh) (ec 1.1.1.30), a ketone body converting enzyme in mitochondria, has been studied in two populations of mitochondria (heavy and light) of jerboa (jaculus orientalis) liver. the results reveal significant differences between the bdh of the two mitochondrial populations in terms of protein expression, kinetic parameters and physico-chemical properties. these results suggest that the beta-hydroxybutyra ... | 2006 | 16455281 |
| seasonal variations of the beta-endorphin neuronal system in the mediobasal hypothalamus of the jerboa (jaculus orientalis). | the distribution of neurons expressing beta-endorphin immunoreactivity was explored in the brain of adult jerboa during two distinct periods characterizing its reproductive cycle. a large presence of cell bodies displaying beta-endorphin immunoreactivity occured within different parts of the mediobasal hypothalamus along its rostrocaudal extent, from the retrochiasmatic area to the posterior arcuate nucleus. quantitatively, the highest density of immunoreactive beta-endorphin neurons was noted a ... | 2005 | 15698930 |
| role of the pineal gland and melatonin in the photoperiodic control of hypothalamic gonadotropin-releasing hormone in the male jerboa (jaculus orientalis), a desert rodent. | the neuroendocrine mechanism underlying seasonal changes in gonadal activity of the jerboa, a desert hibernating rodent adapted to harsh climatic conditions, are poorly understood. we investigated the role of the pineal gland and melatonin in the photoperiodic control of hypothalamic gonadotropin-releasing hormone (gnrh). intact and pinealectomized male jerboas were subjected to short photoperiod, while others were kept under long photoperiod and injected daily with melatonin or vehicle. testes ... | 2005 | 15607825 |
| peroxisome proliferator-activated receptors as regulators of lipid metabolism; tissue differential expression in adipose tissues during cold acclimatization and hibernation of jerboa (jaculus orientalis). | brown (bat) and white (wat) adipose tissues play a key role in the body energy balance orchestrated by the central nervous system. hibernators have developed a seasonal obesity to respond to inhospitable environment. jerboa is one of the deep hibernator originated from sub-desert highlands. thus, this animal represents an excellent model to study cold adaptation mechanism. we report that the adipogenic factor ppargamma exhibits a differential expression between bat and wat at mrna level. a speci ... | 2004 | 15589684 |
| different thermostability of skeletal muscle glyceraldehyde-3-phosphate dehydrogenase from hibernating and euthermic jerboa (jaculus orientalis). | in previous study, we demonstrated that the specific activity of d-glyceraldehyde-3-phosphate dehydrogenase (gapdh, ec 1.2.1.12) in skeletal muscle of induced hibernating jerboa (hibernating gapdh) was 3 4 folds lower than that of the one in the skeletal muscle of the euthermic jerboa (euthermic gapdh). a significant decrease in both gapdh protein and gapc mrna levels occurs when hibernating, but the purified hibernating gapdh is less active than the euthermic gapdh. to investigate the physico-c ... | 2003 | 14515205 |
| changes of peroxisomal fatty acid metabolism during cold acclimatization in hibernating jerboa (jaculus orientalis). | jerboa (jaculus orientalis) is a deep hibernator originating from sub-desert highlands and represents an excellent model to help to understand the incidence of seasonal variations of food intake and of body as well as environmental temperatures on lipid metabolism. in jerboa, hibernation processes are characterized by changes in the size of mitochondria, the number of peroxisomes in liver and in the expression of enzymes linked to fatty acid metabolism. in liver and kidney, cold acclimatization ... | 2003 | 14505827 |
| hibernation impact on the catalytic activities of the mitochondrial d-3-hydroxybutyrate dehydrogenase in liver and brain tissues of jerboa (jaculus orientalis). | jerboa (jaculus orientalis) is a deep hibernating rodent native to subdesert highlands. during hibernation, a high level of ketone bodies i.e. acetoacetate (acac) and d-3-hydroxybutyrate (boh) are produced in liver, which are used in brain as energetic fuel. these compounds are bioconverted by mitochondrial d-3-hydroxybutyrate dehydrogenase (bdh) e.c. 1.1.1.30. here we report, the function and the expression of bdh in terms of catalytic activities, kinetic parameters, levels of protein and mrna ... | 2003 | 12964952 |
| induction of the expression of the peroxisome proliferator-activated receptor alpha (pparalpha) by clofibrate in jerboa tissues. | peroxisome proliferator-activated receptor alpha (pparalpha) is a member of the nuclear hormone receptor superfamily that can be activated by natural fatty acids and various xenobiotics, including clofibrate. this transcription factor primarily regulates genes involved in lipid metabolism and homeostasis. we present the expression pattern of the pparalpha subtype in the adult jerboa jaculus orientalis, determined by rt-pcr and western blotting using specific probes and a polyclonal antibody for ... | 2003 | 12740825 |
| testosterone-dependent and -independent mechanisms involved in the photoperiodic control of neuropeptide levels in the brain of the jerboa (jaculus orientalis). | vasoactive intestinal peptide (vip) and neuropeptide y (npy) content in the suprachiasmatic nucleus have been shown to exhibit seasonal changes with an increase in late summer, the period of sexual quiescence in the jerboa (jaculus orientalis). in this study, vip content in the scn and npy and enkephaline (enk) content in the geniculo-suprachiasmatic system have been assayed in wild-caught male jerboas (jaculus orientalis) in order to determine whether these neuropeptides are controlled directly ... | 2003 | 12650966 |
| purification and characterization of cytosolic glycerol-3-phosphate dehydrogenase from skeletal muscle of jerboa (jaculus orientalis). | cytosolic glycerol-3-phosphate dehydrogenase was purified from jerboa (jaculus orientalis) skeletal muscle and its physical and kinetic properties investigated. the purification method consisted of a multi-step procedure and this procedure is presented. the specific activity of the purified enzyme is 53.6 u/mg of protein, representing a 77-fold increase in specific activity. the apparent michaelis constant (km) for dihydroxyacetone is 137.39 (+/- 25.56) microm whereas the km for glycerol-3-phosp ... | 2002 | 11952153 |
| neuronal activity in the mediobasal hypothalamus of hibernating jerboas (jaculus orientalis). | the expression of the c-fos protein in the mediobasal hypothalamus (mbh) of the jerboa was examined both during hibernation and on arousal from hibernation. expression was examined by c-fos immunohistochemistry using a polyclonal antibody raised against c-fos protein. in jerboas hibernating for 2 days, a significant number of c-fos immunopositive neurons were found in the median eminence and ventrolateral arcuate nucleus. such an immunoreaction was not observed in non hibernating control animals ... | 1999 | 10027688 |
| the developmental order of bipedal locomotion in the jerboa (jaculus orientalis): pivoting, creeping, quadrupedalism, and bipedalism. | this is a brief report on the postnatal development of locomotor behavior in the jerboa, a bipedal kangaroo-like rodent. observations on one litter revealed three intriguing aspects of the postnatal development of the jerboa compared to other rodent species: (a) the weaning period is extended, (b) the developmental stage in which pivoting is the main locomotor activity is extended, and (c) locomotor performance is differently related to anatomical growth. jerboa pups are born after a long pregna ... | 1997 | 9298639 |
| characterization of opioid peptides and opioid receptors in the brain of jerboa (jaculus orientalis), a hibernating rodent. | the present study was undertaken to investigate the biochemical characteristics of the opioid receptors and opioid peptides in the jerboa (jaculus orientalis) brain, a subdesert rodent of morocco. we have demonstrated the presence of delta, mu, and kappa sites in the jerboa brain. the endogenous opioid peptides methionine-enkephalin, beta-endorphin, and dynorphin were evaluated in different physiological states of the animal (active and hibernating). the circulating methionine-enkephalin in diff ... | 1997 | 9365806 |
| [postnatal development of renal concentrating ability in a desert rodent, jaculus orientalis]. | postnatal development of renal function was studied in newborn jerboa from six weeks after birth. the results showed that the renal capacity of urine-concentration was more or less analogous to that of the adult, starting 15 weeks after birth when the animal reached a body weight of about 70 to 90 g. from the 13th week onwards, the u/p ratio of the osmolality in function of age, increases when the urinary debit decreases. the osmotic-clearance and the free water-clearance will show stability 15 ... | 1997 | 9221018 |
| evidence for a posttranslational covalent modification of liver glyceraldehyde-3-phosphate dehydrogenase in hibernating jerboa (jaculus orientalis). | the specific activity of d-glyceraldehyde-3-phosphate (g3p) dehydrogenase (phosphorylating) (gpdh, ec 1.2.1.12) found in liver of induced hibernating jerboa (jaculus orientalis) was 2-3-fold lower than in the euthermic animal. however, the comparative analysis of the soluble protein fraction of these tissues by sds-page and western blotting showed no significant changes in the intensity of the 36 kda protein band of the gpdh subunit. after using the same purification procedure, the gpdh from liv ... | 1996 | 8547342 |
| vasopressin in the brain of a desert hibernator, the jerboa (jaculus orientalis): presence of sexual dimorphism and seasonal variation. | the distribution of vasopressin innervation in the brain of the jerboa (jaculus orientalis) was investigated, with special attention to sex differences and seasonal variations. vasopressin perikarya were observed in the paraventricular and supraoptic nuclei, the suprachiasmatic nucleus, the periventricular nucleus, the medial preoptic area, the bed nucleus of the stria terminalis, and the medial amygdaloid nucleus. in addition, vasopressin cell bodies were observed in the ventral retrochiasmatic ... | 1995 | 7593745 |
| effects of cold exposure and hibernation on renal na,k-atpase of the jerboa jaculus orientalis. | changes in activity and abundance of renal na,k-atpase were evaluated during cold exposure and hibernation of the jerboa jaculus orientalis by measuring the hydrolytic activity, the number of units and the transport activity of na,k-atpase in isolated nephron segments. as compared to controls, jerboas exposed to cold (6 degrees c) for 4-5 weeks displayed mild diuresis, decreased urinary osmolality and increased kaliuresis. in cold-exposed jerboas, na,k-atpase hydrolytic activity was reduced in t ... | 1995 | 7491273 |
| seasonal variation in npy immunoreactivity in the suprachiasmatic nucleus of the jerboa (jaculus orientalis), a desert hibernator. | using immunocytochemical techniques the seasonal variation in npy immunoreactive fibers was investigated in the suprachiasmatic nucleus of both male and female jerboas. during the period of sexual quiescence (autumn), the amount of npy immunoreactive fibers in the suprachiasmatic nucleus of both male and female jerboas was higher than in the period of sexual activity (spring-middle of summer). compared with the respective control groups, castration during the period of sexual activity and testos ... | 1995 | 7566664 |
| characterization of muscle glyceraldehyde-3-phosphate dehydrogenase isoforms from euthermic and induced hibernating jaculus orientalis. | the specific activity of d-glyceraldehyde-3-phosphate (g3p) dehydrogenase (phosphorylating) (gpdh, ec 1.2.1.12) found in skeletal muscle of induced hibernating jerboa (jaculus orientalis) was 3-4-fold lower than in the euthermic animal. the comparative analysis of the soluble protein fraction of these tissues by sds-page and western blotting showed a significant decrease in the intensity of a protein band of about 36 kda, the gpdh subunit, in hibernating jerboa. after using the same purification ... | 1995 | 7873559 |
| stimulus-secretion coupling in the neurohypophysis of the jerboa jaculus orientalis. | 1. in many mammals, severe dehydration is known to cause exhaustion of the vasopressin content of the neural lobe. here, we have examined the physiological state of the neurohypophysis of the jerboa jaculus orientalis, a rodent inhabitant of a semi-desert climate. 2. isolated neurohypophyses and neurosecretory nerve endings were perfused in vitro and vasopressin and oxytocin release were determined by radioimmunoassay. 3. electrical stimulation of the neurohypophysis with bursts of pulses mimick ... | 1994 | 7964410 |
| opioid binding sites in jerboa (jaculus orientalis) brain: a biochemical comparative study in the awake-active and induced hibernating states. | 1. using tritiated ligands [3h]dadle, [3h]dago, [3h]ekc and [3h]bremazocine, we have demonstrated the presence of delta, mu and kappa sites in brain membranes from jerboa (jaculus orientalis), a desert rodent and a true hibernator. 2. a comparative study was realized in the case of the induced hibernating state, indicating a reduction of binding capacities during the hibernation state. 3. using radioimmunoassay, the endogenous pentapeptide methionine-enkephalin (met-enk) was evaluated in differe ... | 1993 | 8386995 |
| sexual differences and seasonal variations in vasoactive intestinal peptide immunoreactivity in the suprachiasmatic nucleus of jerboa (jaculus orientalis). | the sexual differences and the seasonal variation in the vasoactive intestinal peptide (vip) content of the suprachiasmatic nucleus (scn) of a desert rodent, the jerboa (jaculus orientalis) were studied using immunocytochemical techniques. during the period of sexual activity (spring-early summer), the vip immunoreactivity in the scn was higher in females than in males. in the period of sexual quiescence (autumn), both males and females exhibited an even more intense vip immunoreaction in the sc ... | 1992 | 1436710 |
| seasonal variations in pineal 5-methoxytryptophol (5-ml) concentrations and in the daily pattern of pineal 5-ml and melatonin in the desert rodent jaculus orientalis: effect of prolonged illumination during the night. | seasonal variations in daytime pineal 5-methoxytryptophol (5-ml) and in the daily pattern of both pineal 5-ml and melatonin concentrations were measured by radioimmunoassay in male and female jerboas, jaculus orientalis. pineal 5-ml content was found to be low in winter and spring and showed a short but marked increase in summer. a clear daily rhythm was present in pineal 5-ml in september, with high concentrations during daytime and low concentrations during nighttime. in may there was a consid ... | 1992 | 1432574 |
| comparison of muscle phosphofructokinase from euthermic and hibernating jaculus orientalis. purification and determination of the quaternary structure. | 1. the structural properties of skeletal muscle phosphofructokinase from euthermic and hibernating jerboa were compared. 2. the enzyme was purified by a rapid procedure; suspended in ammonium sulfate in the presence of atp, it was found to be stable for three weeks. 3. a specific activity of 76 u/mg and at most 65 u/mg was obtained for the enzyme from the euthermic and hibernating jerboa, respectively. 4. the molecular weight was estimated to be 320 kda for the oligomer and 80 kda for the subuni ... | 1992 | 1386797 |
| regulation of the skeletal muscle metabolism during hibernation of jaculus orientalis. | 1. the glycolytic flow in the skeletal muscle was considerably depressed during hibernation of jaculus orientalis. 2. although the atp content was not modified, the atp/amp ratio was twice as large than under homeothermic conditions. 3. furthermore, the hexose phosphates were markedly depressed. 4. the total activities of the key enzymes, hexokinase, phosphofructokinase and pyruvate kinase, which are regulated through the adenylates, decreased. 5. under in vivo conditions, taking into account th ... | 1990 | 2143971 |
| conformational modification of muscle phosphofructokinase from jaculus orientalis upon ligand binding. | phosphofructokinase from jaculus orientalis muscle is an allosteric enzyme regulated by substrates and nucleotide effectors. the conformational modifications upon ligand binding were probed by uv difference spectra and reactivities of thiol groups towards dithiobisnitrobenzoate and n-ethylmaleimide. the binding of fru-6-p induced significant perturbations in the environment of the aromatic residues and buried the most reactive on the three accessible cysteines per protomer. the same effect on th ... | 1989 | 2522395 |
| hormonal control of lipolysis from the white adipose tissue of hibernating jerboa (jaculus orientalis). | 1. plasma glucose, glycerol, free fatty acids and total lipid content of the white adipose tissue were measured in euthermic and hibernating jerboa. 2. during hibernation, plasma glucose and glycerol were low compared to the euthermic animals, whereas there was no obvious difference in plasma free fatty acids. the white adipose tissue lipid content was strongly reduced in the hibernating state. 3. the effect of lipolytic hormones (norepinephrine and glucagon) and antilipolytic hormone (insulin) ... | 1988 | 2907428 |
| effect of water intake on na-k-atpase in nephron segments of the desert rodent, jaculus orientalis. | na-k-atpase activity was measured in individual pieces of nephron microdissected from collagenase-treated kidneys of jerboas, jaculus orientalis. na-k-atpase activity was high in the distal convoluted tubule, intermediate in the thick ascending limb of the loop of henle and low in the proximal and collecting tubule. when jerboas were adapted for several weeks to a hydrated diet and excreted a more diluted urine, na-k-atpase activity was altered in specific segments of the nephron: 1. in the prox ... | 1987 | 3031578 |
| tolerance of one species of jerboa (jaculus orientalis) to prolonged exposure to deep hypothermia. | | 1974 | 4468974 |