| evidence of three cell types in the islets of langerhans in sand rats (psammomys obesus). | the islets of langerhans of sand rats were examined light- and electron microscopically with respect to the presence of various cell types. apart from a- and b-cells, already known in sand rats, the presence of the third type of cells was established in the islet organ. according to their topography, argyrophilia (hellman and hellerström technique) and electron microscopical appearance of their granules they should be considered as d-cells. | 1979 | 398106 |
| [presence of biogenic amines in the langerhans' islets of the sand rat (psammomys obesus) (author's transl)]. | the islets of langerhans of sand rats (psammomys obesus) have been investigated ultrahistochemical in order to demonstrate biogenic amines. it could be found that amine containing vesicles with a diameter of 600 to 700 nm from the type of catecholamine granules exist in a-cells as well as in b-cells. further, 2 very rare cell types not containing specific hormone granules could be found. these cells contain particles, in one case similar to catecholamine granules and in the other case representi ... | 1977 | 412391 |
| degeneration of the intervertebral disks and spondylosis in aging sand rats. | aging sand rats (psammomys obesus) kept on a standard laboratory diet supplemented by salt bush--their natural source of food--were examined for changes of the vertebral column. from about 6 months of age on, degeneration of the intervertebral disks was noted. the changes increased in severity with increasing age, and from 1 1/2 years of age on, massive multiple disk herniations were seen. associated with these lesions were spondylosis of "intervertebral" as well as hyperostotic type, and osteoa ... | 1979 | 582256 |
| insulin and glucagon secretion by pancreatic islets from nondiabetic and diabetic sand rats (psammomys obesus). | the secretion of insulin and glucagon was investigated in pancreatic islets from diabetic and nondiabetic sand rats of similar age and weight. the metabolic characterization was based on an intraperitoneal glucose tolerance test. compared to nondiabetic animals diabetic sand rats had a diminished insulin content in their islets and a decreased insulin secretory response to glucose, glyceraldehyde and theophylline. diazoxide inhibited insulin release in diabetic as well as in nondiabetic sand rat ... | 1976 | 767120 |
| ultrastructure and behavior of the achiasmatic, telosynaptic xy pair of the sand rat (psammomys obesus). | | 1977 | 891351 |
| cutaneous leishmaniasis in the libyan arab republic: preliminary ecological findings. | preliminary results show cutaneous leishmaniasis in libya to be, sometimes at least, a rural zoonotic infection. the parasites are transmitted, probably by phlebotomus papatasi, between the rodents psammomys obesus and meriones libycus. the banks and 'islands' in the main channel of seasonal wadis provide the right combination of vegetation and permanence for the maintenance of an intense focus. | 1977 | 921363 |
| neoplastic liver nodules of unknown cause in a colony of sand rats (psammomys obesus). | | 1976 | 990139 |
| ecoepidemiology of leishmaniases in syria. 3. leishmania major infection in psammomys obesus provides clues to life history of the rodent and possible control measures. | collections of psammomys obesus from near damascus, syria in may 1990 and november 1991 contained animals of all ages. both series had a high prevalence of leishmania major infection. lesions were small in november and large in may. assuming the two collections were representative of typical years, it is inferred that the breeding season is between october and may: there is high winter mortality of animals born early in the breeding season, but high survival of their parents, and there is high m ... | 1992 | 1301732 |
| diabetes mellitus in sand rats (psammomys obesus): microangiopathy during development of the diabetic syndrome. | the purpose of the study was to investigate the development of microangiopathic complications in north african sand rats with diabetes induced by a long-term standard laboratory diet. hyperinsulinaemic rats, whether non-diabetic obese or diabetic, developed capillary basement membrane (cbm) thickening in the skin; in insulin-dependent animals, this change was diffuse. many pas positive areas were demonstrated in skeletal muscle and myocardium, together with evidence of microangiopathy; the prima ... | 1991 | 1747900 |
| histomorphometric analysis of weight bearing bones of diabetic and non-diabetic sand rats (psammomys obesus). | femoral and tibial bones of diabetic sand rats were compared to those of non-diabetic sand rats (psammomys obesus) of the same age range. three morphometric parameters were examined: trabecular bone volume, length of epiphyseal cartilage (proliferative and mature) and cortical thickness of mid-shaft of tibia. there were no statistically significant differences between the test and control animals for the last two parameters. by contrast the trabecular bone volume of the diabetic animals was less ... | 1991 | 1841029 |
| the structural organization of the kidney of the desert rodent psammomys obesus. | the architecture of the desert rodent psammomys obesus has been studied by means of standard histologic procedures and by single nephron injections. as other rodent kidneys (rat, mouse), the psammomys kidney consists of two types of nephrons, 66% short looped and 34% long looped nephrons. the cortex is composed of 4 to 5 layers of glomeruli, which lie closely put together, the glomeruli often touch each other. the superficial and the midcortical glomeruli give rise to short looped neophrons, the ... | 1975 | 1211658 |
| stress-induced inhibition of triglyceride secretion in vivo sand rats (psammomys obesus). | the effects of acute stress upon circulating triglyceride, glucose, insulin, free fatty acids, and glycerol were investigated in obese desert sand rats. three groups of animals, designated "nonstress", "non-exertional stress", and "exertional stress", were studied. acute stress, with or without accompanying exercise, was associated with significant decreases in circulating triglyceride; significant increases in circulating glucose, free fatty acids, and glycerol; and variable changes in circulat ... | 1976 | 994840 |
| role of sodium and urea in the renal concentrating mechanism in psammomys obesus. | micropunctures were performed at the tip of henle's loops and vasa recta accessible at the extrarenal surface of the papilla in a desert rodent (psammomys obesus) studied under mild nacl ((nacl 4%, 0.0375 ml/min) and mild urea (urea 4%, 0.0375 ml/min) loading conditions. in nacl loaded animals, it was confirmed that solute addition (mainly sodium) contributes in a large proportion to the concentrating process along the thin descending limb. comparison of sodium and urea concentrations in the lo ... | 1976 | 943085 |
| [immunhistochemical evidence of insulin and glucagon in the islets of langerhans of the sand rats (psammomys obesus) (author's transl)]. | | 1975 | 811062 |
| immunohistochemical investigations of the endocrine pancreas in normoglycemic sand rats (psammomys obesus). | a morphological analysis of the endocrine pancreas in the normoglycemic sand rat (psammomys obesus) has been carried out and the immunoreactivity for insulin, glucagon, somatostatin and pancreatic polypeptide (pp) studied. the islets of both parts of the pancreas (pancreatic head and tail) investigated were of the 'mantle' type: centrally located b-cells and a-, d- and pp-cells at the periphery. in the 'glucagon islets' (tail of pancreas) predominated the a-cells, while the pp-cells were more ab ... | 1989 | 2483485 |
| pancreatic b-cell behaviour after changing the natural environment of sand rats (psammomys obesus. | on the basis of the blood glucose increase during the capitivity sand rats born in the desert were classified as normals, protodiabetics and diabetics, indicating a different adaptation to the new environment within a definite period. isolated islets of animals, which did not develop a hyperglycemia, enhanced their insulin content during the adaptation period. the absolute insulin secretion rates in response to 16.5 mm glucose were rather similar between the three investigated groups and not mod ... | 1976 | 795642 |
| glucose-induced insulin secretion and insulin sensitivity of peripheric organs of egyptian sand rats before manifestation of diabetes. | in egyptian sand rats (psammomys obesus) fed with native food and a low caloric vegetable diet after capture it was possible to study endocrinologic and metabolic changes of the early stages during the progression to diabetes. according to body weight gain and fasting blood glucose the animals were differentiated into two groups classified as basic and protodiabetic group, respectively. isolated pancreatic islets as well as the perfused pancreases of sand rats responded to low concentrations of ... | 1976 | 795636 |
| age-related changes in fibronectin in annulus fibrosus of the sand rat (psammomys obesus). | fibronectin stains were carried out and evaluated by microspectrophotometric techniques in annuli fibrosi of vertebral discs of sand rats (psammomys obesus) of both sexes and two age groups, 13-18 months and over 2 years of age. the distribution of fibronectin in the annulus shows a centripetal gradient from the outer to the inner laminae. fibronectin was significantly more abundant in the annuli of old than of young animals of corresponding sex. sex differences were not significant. the dorsal ... | 1989 | 2696656 |
| investigations on isolated islets of langerhans in vitro. xiv. insulin secretion and insulin stores of cultivated islets from sand rats (psammomys obesus): investigations of glucose-dose response. | release of immunoreactive insulin activity (iri) and biological insulin like activity (ila) from collagenase isolated pancreatic islets of sand rats (psammomys obesus) maintained on a vegetable diet were examined at 60 min and 24-48 h intervals under culture conditions at 1.0 and 15.6 mm glucose. the glucose-insulin dose response curves for sand rats after 60 min incubation were compared with those after 24 or 48 h of incubation. the pancreatic islets responded to 5mm glucose with a high insulin ... | 1976 | 793840 |
| insulin secretion of isolated islets of sand rats (psammomys obesus) during adaptation on captivity. | in normoglycemic sand rats the insulin secretion of isolated islets was investigated dependent on the time of artificial nutrition in captivity. whereas the islets of short-term adapted animals did not respond within 15 min with an enhanced insulin secretion after stimulation with 16.5 mm glucose or 10 mm arginine, prolongation of incubation time resulted in a significantly enhanced hormone release. an intraveneous glucose injection (1 g/kg body weight) 45 min prior to the excision of the pancre ... | 1975 | 765126 |
| insulin and glucagon degradation in livers of sand rats (psammomys obesus). | | 1977 | 616717 |
| variations of glucose utilization in muscle and adipose tissue of sand rats (psammomys obesus) during adaptation to laboratory holding. | sand rats, captured in egypt and fed with a low caloric vegetable diet during adaptation, were investigated before and after 2.5 and 8 weeks diet treatment (30 and 40 kcal/100 g body weight daily). in hexobarbital anaesthesia the sand rats were loaded with 1 g glucose/kg body weight in a single dose intravenously. after a rapid increase the content of glucose in blood remained at a level of about 600 mg glucose/100 ml blood. the insulin immunoreactivity in blood did not change uniformly after ap ... | 1977 | 608459 |
| the problem of diabetic angiolopathy in sand rats (psammomys obesus). | no diabetic angiolopathy was found in the retinas, kidneys and skeletal muscles of protodiabetic and overtly diabetic sand rats. the terminal blood vessels were investigated using histological, enzyme histochemical, immunofluorescence microscopic, autoradiographic and electron microscopic methods. there seems to be little or no connection in sand rats between the diabetic metabolism syndrome and the metabolic process leading to angiolopathy. | 1977 | 608458 |
| pericapsular smooth muscle cells in renal corpuscles of the mongolian gerbil. | during the course of a systematic investigation of the renal corpuscles in various desert rodents (meriones unguiculati, meriones shawii, psammomys obesus, and dipodymis), a thickened bowman's capsule was observed light microscopically in some kidneys of adult meriones unguiculati (mongolian gerbil). electron microscopic studies show that this unusual finding may depend on the presence of one or two layers of typical smooth muscle cells adjacent to the outer surface of the basal lamina. in the k ... | 1979 | 572742 |
| establishment of an albino sand rat (psammomys obesus colony and comparison with the natural coloured animal. | the lifespan and fertility of albino sand rats were found to be severely reduced in comparison with a laboratory colony of brown sand rats. the albinos were also much more susceptible to diabetes, as judged by their glucose tolerance. in fact, untreated albinos had a higher incidence of diabetic response than coloured sand rats fed a diabetogenic diet. the albino sand rats reproduced poorly because of a reduction in male fertility. circulating testosterone levels and seminal vesicle weights were ... | 1978 | 564421 |
| otic cholesteatoma in the sand rat (psammomys obesus). | to improve treatment of otic cholesteatoma, a model is needed for conduction of experiments. in the search for such a model, we have found cholesteatoma to occur naturally in psammomys obesus. we present these findings and suggest the fat sand rat as a model for investigating cholesteatoma. | 1988 | 3059810 |
| effects of hyperinsulinism and of diabetes on proteoglycans of the intervertebral disc in weanling sand rats. | weanling sand rats (psammomys obesus) develop hyperinsulinemia or diabetes or both, if fed a standard laboratory diet without a supplement of fiber rich salt bush. the annuli fibrosi of hyperinsulinemic or diabetic animals, which are still hyperinsulinemic, show a slight but statistically significant increase in chondroitin sulfate and a lesser, statistically nonsignificant increase in keratan sulfate. possible causes of these changes are discussed and the likelihood of a role of hyperinsulinism ... | 1986 | 3091415 |
| cultivation of besnoitia besnoiti and evaluation of susceptibility of laboratory animals to cultured parasites. | cultivation of besnoitia besnoiti on five mammalian cell types showed that vero (green monkey kidney), l929 (mouse fibroblasts) and bek (bovine embryo kidney) cells were highly susceptible and were almost destroyed after 5 days of incubation, while mdbk (madin-darby bovine kidney) and bl (theileria annulata-infected bovine lymphoid) cells were less affected. intraperitoneal infection with culture-derived endozoites was fatal for gerbils (meriones tristrami) and sand rats (psammomys obesus). rabb ... | 1987 | 3105163 |
| [histological investigations on adrenal cortex of sand rats (psammomys obesus) during development of the diabetes mellitus (author's transl)]. | the investigations were carried out on 20 sand rats (6 prediabetic, 6 diabetic and 8 normoglycemic animals). the cortices of adrenal glands were studied with histological methods. the thickness of the zona glomerulosa is in this 3 groups different. in the prediabetic group is the zona glomerulosa higher, in the diabetic group lower than the normoglycemic group. the relationship is 1.5 (normoglycemic group) : 2.9 (prediabetic group) : 0.8 (diabetic group). it is concluded that the zona glomerulos ... | 1979 | 474988 |
| cardiac output distribution in thermally dehydrated rodents. | the effect of thermal dehydration (37 degrees c) on the integrated response of the circulation was studied in conscious laboratory rats and in the desert species psammomys obesus, the latter being studied prior to and following acclimation to heat. cardiac output (co) and its distribution were measured using labeled microspheres with the reference organ technique. at low dehydration (7-9% body wt loss) rats showed peripheral vasodilation coincidentally with splanchnic vasoconstriction, whereas t ... | 1988 | 3276223 |
| altered tissue content of trace metals in diabetic hyperinsulinaemic sand rats (psammomys obesus). | the concentrations of zinc, copper, and chromium in liver, kidney, muscle, bone and serum from control normoinsulinaemic and hyperinsulinaemic sand rats (psammomys obesus) and from untreated spontaneously hyperinsulinaemic-hyperglycaemic sand rats were compared. a chronic hyperinsulinaemic-hyperglycaemic state was associated with a significant reduction (p less than 0.01) of zinc concentration in the liver, kidney and muscle but an elevation of zinc content in bone and of chromium in the liver. ... | 1988 | 3294070 |
| studies on (pro)insulin biosynthesis and secretion of pancreatic islets of sand rats (psammomys obesus) after different feeding conditions. | it was possible to induce different metabolic states in sand rats of our breeding colony or in newly caught egyptian sand rats, respectively, by feeding a pellet diet or vegetable diet (green cabbage). newly captured sand rats fed only on native food were used as reference group (group c). plasma iri-level and glucose in vivo and [3h]-leucine incorporation into proinsulin and insulin, insulin secretion and insulin content in vitro were investigated. sand rats fed on pellet chow and ad libitum (g ... | 1979 | 389618 |
| occurrence of biogenic amines in the pancreatic islets of sand rats (psammomys obesus). | the islets of langerhans of sand rats (psammomys obesus) have been investigated ultrahistochemically in order to demonstrate biogenic amines. it could be found that amine-containing vesicles with a diameter of 600-700 nm from the type of catecholamine-granules exist in a-cells as well as in b-cells. it can be stated that the sand rat belongs to the species containing amines in a- and b-cells. the importance of the amines for the regulation of the hormone secretion of the islets of langerhans is ... | 1977 | 334526 |
| studies on the (pro) insulin biosynthesis of islets of langerhans of sand rats (psammomys obesus). | by feeding a regular laboratory chow, sand rats (psammomys obesus) from our breeding colony gained different body weights, though they received approximately the same quantity of calories. sand rats, reaching a body weight above 160 g (group b) showed significantly increased blood glucose values in contrast to the animals with a body weight under 160 g (group a). isolated pancreatic islets of these two groups of sand rats were incubated with [3h]-leucine to study the incorporation of this amino ... | 1977 | 334524 |
| the histogenesis of hepatoma occurring spontaneously in a strain of sand rats (psammomys obesus). | spontaneous hepatomas and hepatic preneoplastic changes were observed in sand rats (psammomys obesus) from two colonies. both colonies originated from 10 sand rats captured in the judean desert in 1969. at the age of 6 months, and increasing in multiplicity with advancing age, histologic examination revealed nodules containing hepatocytes characterized by hyperbasophilia, accumulation of glycogen, eosinophilic cytoplasm, or a mixture of these cells. in animals over 25 months old hepatocellular c ... | 1978 | 203193 |
| [enzyme histochemistry of the sand rat pancreas (psammomys obesus) after different caloric food]. | in a complex investigation were evidenced 12 selected enzymes (oxidoreductases and hydrolases) in the pancreas of normoglycemic sand rats (psammomys obesus). the sand rat developed a spontaneous diabetic metabolism by holding in the vivarium. the material based of animal groups that were fooded ad libitum or after defined dietetic regimes. the topochemical pattern of enzymes in the langerhans' islets and exocrine acini can be compared between the sand rat groups and with the good investigated mo ... | 1976 | 189556 |
| occurrence of somatostatin-like immunoreactivity (sli) in the dorsal hippocampus of the sand rat (psammomys obesus). | somatostatin-like immunoreactivity (sli) was demonstrated in neurons of the dorsal hippocampus of the sand rat by means of the immunofluorescence technique. | 1979 | 120101 |
| [occurrence of glycogen-deposites in acinar cells of pancreas in prediabetic sand rats (psammomys obesus) (author's transl)]. | the investigations were in 6 prediabetic and 8 normoglycemic sand rats carried out with a histochemical method (pas-reaction). glycogen is present in pancreatic acinar cells in various quantity. it is in the cytoplasm homogenously distributed. the pas positive acini are near the islets of langerhans localized, which have in their b cells also glycogen deposites. the phenomenon is by the vascularisation of the pancreas explained. | 1979 | 112823 |
| leishmania infecting man and wild animals in saudi arabia. 2. leishmania arabica n. sp. | leishmania arabica n. sp., found in the rodent psammomys obesus in the eastern province of saudi arabia, is described. this parasite, which has also been found in a feral dog in the same area, is distinguished from the common species of the eastern province, l. major zymodeme lon-4, on the basis of its very distinctive isoenzyme profile (zymodeme lon-64) and kinetoplast dna. it is morphologically indistinguishable from l. major. the new parasite has not been found in man to date and its vector i ... | 1986 | 3544354 |
| morphology of the endocrine pancreas in diabetic sand rat (psammomys obesus). | | 1985 | 3891087 |
| studies on the "labile-bound" glucose compartment in erythrocytes: studies on psammomys obesus (sand rat) and preliminary studies on human erythrocytes. | enzymatic (glucose oxidase) measurement of glucose concentration in the fluid compartment of psammomys erythrocytes (gfe) and of its concentration in the fluid compartment of blood plasma (gfp) gives the ratio (mean +/- sd): gfe/gfp = 1.50 +/- 0.43 (n = 12, 23 degrees c). however, when we added 3h-labeled glucose (g*) in vitro to the whole blood, the ratio after 2 min was g*fe/g*fp = 0.90 (sd 0.11) and after 5 min g*fe/g*fp = 0.97 (sd 0.12). these calculations were based on previous determinatio ... | 1985 | 3891141 |
| development of macroangiopathy in sand rats (psammomys obesus), an animal model of non-insulin-dependent diabetes mellitus: effect of gliclazide. | the risk of developing macroangiopathy associated with diabetes led us to study in sand rats the long-term consequences of non-insulin-dependent diabetes on the development of arterial lesions promoted by feeding a high-cholesterol diet. gliclazide, an agent whose preventive effect has previously been suggested in other experimental models of atheroma, was also investigated in these diabetic and hypercholesterolemic animals. sand rats were fed a natural diet (nd group), a standard laboratory fee ... | 1991 | 1872306 |
| seasonal changes in plasma concentrations of gonadotropins and in the responsiveness of the pituitary and testis to gnrh in a desert rodent, the sand rat (psammomys obesus). | the male sand rat (psammomys obesus), captured alive in the sahara desert in the area of béni-abbès (algeria), exhibited seasonal changes in plasma concentrations of lh, characterized by an increase in early summer. administration of a standard dose of gnrh (200 ng/100 g body weight) failed to elicit significant season-dependent changes in lh release, whereas the increase in plasma testosterone was maximum in june-july and quite small between november and march-april. the present results suggest ... | 1991 | 1777059 |
| [quantitative histologic studies of the gonads of sand rats (psammomys obesus) during the development of diabetes mellitus]. | quantitative-histological investigations (point counting method) are pointed out in 27 male and 15 female sand rats. the animals are divided in the igt (impaired glucose tolerance), the diabetic and the control group. the leydig cells are in the igt-group increased, and in the diabetic group decreased. the female sand rats are characterized by the tendency of increase of size and number of follicles in the igt-group. corpora lutea are reduced but atretic follicles are increased in the diabetic g ... | 1991 | 1772129 |
| a herpes virus from sand rats (psammomys obesus). | | 1967 | 4228677 |
| a breeding program for spontaneously diabetic experimental animals: psammomys obesus (sand rat) and acomys cahirinus (spiny mouse). | | 1968 | 4233365 |
| cytomegalic inclusion disease in sand rats (psammomys obesus): histopathologic evidence. | | 1967 | 4294404 |
| establishment of conditions for colony-breeding of the sand-rat psammomys obesus. | | 1972 | 4334435 |
| control of insulin secretion in the egyptian sand rat ((psammomys obesus). | | 1974 | 4375064 |
| adipocyte cellularity in the desert sand rat (psammomys obesus). | | 1974 | 4438313 |
| tyrosine hydroxylase immunoreactivity in the retina of the diabetic sand rat psammomys obesus. | the pattern of tyrosine hydroxylase (th)-immunoreactivity, which labels dopamine neurons in the retina, is described in a diurnal sand rat psammomys obesus. as in other rodent species, dopamine innervation is composed of large neurons located in the amacrine cell layer and sending processes mainly to sublamina 1 of the inner plexiform layer, where they form ring-like structures around unlabeled cell bodies. thin varicose axon-like processes running to sublamina 3 are also present in significant ... | 1991 | 1687044 |
| [pancreas innervation with special reference to islands of langerhans in psammomys obesus, cavia porcellus and canis familiaris]. | | 1973 | 4582420 |
| protein synthesis in pancreatic beta cells of the normal and diabetic egyptian sand rat (psammomys obesus). an autoradiographic study with the electron microscope. | the pattern of protein synthesis was studied in the pancreatic beta cells of the egyptian sand rat (psammomys obesus). when fed a standard purina laboratory chow diet instead of a leafy vegetable diet, these animals develop the characteristic signs of diabetes mellitus. tritiated leucine was injected intravenously into pairs of sand rats (one on a vegetable diet and one on a purina laboratory chow diet). two pairs of animals were sacrificed at 5-, 20- and 60-minute intervals, and pancreatic tiss ... | 1973 | 4586126 |
| ultrahistochemical detection of biogenic amines in a-cells of langerhans islets of sandrats (psammomys obesus) by means of reinecke-salt. | | 1974 | 4607323 |
| [regression of cataract and hyperglycemia in diabetic sand rats (psammomys obesus) having received an extract of eugenia jambolana (lamarck)]. | | 1972 | 4622072 |
| metabolic effects of insulin blockade by d-mannoheptulose in the sand rat (psammomys obesus) and the rat. | | 1972 | 4635465 |
| metabolic pattern of sand rats (psammomys obesus) and rats during fasting. | | 1972 | 4653201 |
| glucose disappearance rates into peripheral tissues of adult rabbits (silvilagus floridans), wistar rats (rattus rattus) and sand rats (psammomys obesus) in relation to body weight and blood glucose concentration. | 1. glucose disappearance rates into peripheral tissues (rd) were measured in vivo in adult eviscerated, nephrectomized and adrenalectomized rabbits, wistar rats and nondiabetic sand rats with physiological insulin concentrations in the blood. 2. the rd of wistar rats was high (7.50 mg/kg/min) in comparison with that of rabbits (2.67 mg/kg/min). in the particular case of sand rats the rd was only 44% of that in wistar rats having about the same body weight. 3. a 2.4-fold elevation of blood glucos ... | 1990 | 1968817 |
| insulin secretion in vitro by the pancreas of the sand rat (psammomys obesus). | | 1968 | 4881994 |
| [the sand rat (psammomys obesus), a spontaneously diabetic animal. a review]. | | 1971 | 4948307 |
| nuttallia meri sp.nov.--a new piroplasm from psammomys obesus in the lower jordan valley. | | 1971 | 5003099 |
| studies on the prediabetes of the sand rat, psammomys obesus. | | 1972 | 5051775 |
| effects of sodium chloride on the water consumption of sand rats (psammomys obesus). | | 1971 | 5092124 |
| [the sand rat (psammomys obesus): an animal subject to spontaneous diabetes]. | | 1971 | 5147110 |
| [ecoepidemiology of leishmaniasis in syria. 1. leishmania major yakimoff and schokhor (kinetoplastida-trypanosomatidae) infestation of psammomys obesus cretzschmar (rodentia-gerbillidae)]. | during an epidemiological survey of zoonotic cutaneous leishmaniasis in south-west syria, leishmania major zymodème mon-26 was isolated from a reservoir host, psammomys obesus terraesanctae (rodentia-gerbillidae). the abundance of this rodent, its close contact with infected villages and the high prevalence of the infection (63,1%) indicate that this is the main reservoir host of oriental sore in the semi desert area of this country. | 1990 | 2097930 |
| acute ketotic-type diabetic syndrome in sand rats (psammomys obesus) with special reference to the pancreas. | | 1966 | 5341114 |
| hypoglycaemic effect of the salt bush (atriplex halimus)--a feeding source of the sand rat (psammomys obesus). | | 1969 | 5372889 |
| the anatomy and histology of the kidney of sand rats (psammomys obesus). | | 1969 | 5405613 |
| cytogenetic studies of the somatic and germ-line cells in sand rats (psammomys obesus). | | 1970 | 5432360 |
| furgher studies on the effect of hypothalamic lesions in the sand rat (psammomys obesus). | | 1970 | 5432361 |
| identification of polypeptide chains in some rodents. i. rattus norvegicus, rattus rattus, psammomys obesus. | | 1971 | 5542935 |
| the sand rat (psammomys obesus) as an experimental animal in studies of diabetes mellitus. | | 1967 | 5621369 |
| spondylosis in sand rats: a model of intervertebral disc degeneration and hyperostosis. | this study defines gross, histopathologic, and radiologic changes associated with intervertebral disc degeneration in a spontaneously occurring form of the disease in aging sand rats (psammomys obesus). sand rats (male/female) fed lab chow supplemented with desert salt bush were sacrificed at periods of 3-30 months. lateral thoracolumbar spine films were obtained. at sacrifice, spines were surgically exposed and gross findings were recorded; after fixation/decalcification, histopathologic studie ... | 1990 | 2182801 |
| effect of diet on the glucose tolerance and plasma insulin levels of the sand rat (psammomys obesus). | | 1966 | 5907154 |
| seasonal changes in plasma testosterone concentrations in response to administration of hcg in a desert rodent, the sand rat (psammomys obesus). | in adult male sand rats inhabiting the béni-abbès area (algeria), testicular endocrine activity increased in early summer (june-july), was highest in autumn-winter and decreased throughout spring. testosterone secretion by the testis of the sand rat was stimulated (by 10-60-fold) throughout the year by exogenously administered hcg (25 i.u.). however, the response exhibited annual changes mainly characterized by a marked increase in early summer (june-july); the response to hcg was depressed in a ... | 1989 | 2644426 |
| anti-leishmanial antibodies during natural infection of psammomys obesus and meriones shawi (rodentia, gerbillinae) by leishmania major. | sera from 77 rodents (psammomys obesus: 64; meriones (m.) shawi: 10; m. libycus: 3) trapped in a focus of zoonotic cutaneous leishmaniasis (zcl) (leishmania (l.) major) were examined for the presence of anti-leishmanial antibodies by the indirect fluorscence antibody technique (ifat) (l. major antigens) using homologous antiglobulins and/or anti-rattus conjugates. sera from 21 animals were positive with titres that ranged from 1: 20 up to 1: 640. the investigation revealed that a good correlatio ... | 1989 | 2658879 |
| hyperalgesia in spontaneous and experimental animal models of diabetic neuropathy. | hyperactivity of nociceptive c-fibers has been recently described in diabetic bb/wistar rats. this study assesses the association of hyperalgesia, using an analgesy-meter, with elevated glycosylated haemoglobin levels in three animal models of diabetic and nutritional neuropathies: psammomys obesus (sand rat), streptozotocin-treated and galactose-fed rats. pain threshold measurements (paw pressure test) and motor nerve conduction velocities were recorded in controls (n = 75), hyperinsulinaemic ( ... | 1987 | 2820821 |
| regulation of lipoprotein lipase activity in the sand rat: effect of nutritional state and camp modulation. | the sand rat (psammomys obesus) is a desert rodent in which obesity and diabetes mellitus appeared only subsequent to feeding laboratory animal chow. to study the role of lipoprotein lipase in the development and maintenance of obesity in the sand rat, enzyme activity in various organs and in plasma of sand rats or albino rats was determined following a 20-hour fast, or 16 hours after injection of cholera toxin. despite comparable change in body weight, an altered pattern of enzyme distribution ... | 1988 | 2848176 |
| blood acid-base status, whole blood and whole body buffer values in sand rats (psammomys obesus) exposed to hypercapnia. | arterial blood acid-base status of unanesthetized sand rats (psammomys obesus) were studied under normocapnic and hypercapnic conditions, and compared to those obtained for the albino rat (rattus norvegicus). the average control blood ph: 7.396 +/- 0.034; paco2: 30.5 +/- 2.9 mmhg; hco-3: 18.8 +/- 2.5 mm/l; and hco-3 std: 20.9 +/- 2.1 (n = 15) obtained here for the sand rat are in the lower range of values found in other mammals and indicate a status of partially compensated metabolic acidosis. t ... | 1985 | 2863043 |
| insulin and glucagon binding to isolated hepatocytes of egyptian sand rats (psammomys obesus): evidence for an insulin receptor defect. | to determine whether a defect in insulin binding could contribute to insulin resistance in egyptian sand rats (psammomys obesus), insulin binding to isolated hepatocytes from euglycemic sand rats was compared to that of normal sprague-dawley rats (rattus norvegicus). because of its potential importance in glucoregulation, glucagon binding to hepatocytes from these species was also measured. hepatocytes of sand rats exhibit an almost complete lack of insulin receptors compared to hepatocytes from ... | 1984 | 6147232 |
| leishmaniasis in the jordan valley. v. dispersal characteristics of the sandfly phlebotomus papatasi. | several characteristics of dispersing and non-dispersing phlebotomus papatasi (scopoli) were quantified and compared. the majority of dispersing sandflies, trapped crossing fallow fields, were females (68.5% v. 51.1%); of the dispersing females, 55.4% were parous, 48.1% were inseminated and 11.6% were gravid. in the population of sandflies sampled exiting from burrows of the sand rat psammomys obesus cretschmar, these categories, respectively, represented 39%, 90% and 26% of the females examined ... | 1988 | 2980198 |
| studies on insulin secretion and the pituitary insulin secretagogue beta-cell-tropin in the sand-rat (psammomys obesus). | the sand-rat (psammomys obesus) is an animal model for the study of human maturity onset diabetes which appears to be controlled by caloric intake. in the present investigations, these animals have been studied in relation to the influence of low- and high-energy diets on body weight, plasma insulin and blood glucose levels, and on insulin secretion from the perfused pancreas and the secretion of corticotropin-like intermediate lobe peptide (clip, acth18-39) and the insulin secretagogue beta-cel ... | 1987 | 3032819 |
| cutaneous leishmaniasis in jordan: biochemical identification of human and psammomys obesus isolates as leishmania major. | as part of a series of epidemiological and ecological studies of leishmaniasis in jordan, we have made functional studies of four isolates from human lesions and from ear lesions of three field-collected psammomys obesus. primary isolates were subcultured, frozen stabilates prepared and balb/c mouse infectivity experiments initiated. each mouse was inoculated with 4-8 x 10(4) promastigotes into a hind footpad. quantitative evaluation of the footpads showed enlargement three to four weeks postino ... | 1988 | 3041929 |
| histologic and morphometric observations on vertebral bone of aging sand rats. | the trabecular bone of the vertebrae of 30 male and 30 female sand rats (psammomys obesus) aged 13 to 33 months was examined histologically and morphometrically. the usual age-linked decline of bone mass failed to occur in females and was statistically not significant in males. a few changes with age were noted at the cellular level. sex differences were statistically significant only in animals living into the third year of life, males having a smaller bone mass than females. this abnormality o ... | 1988 | 3043718 |
| [the new focus of cutaneous leishmaniasis of m'sila (algeria). natural infection cf psammomys obesus (rodentia, gerbillidae)]. | the m'sila region has been recently the theatre of an important outbreak of cutaneous leishmaniasis. the search for the animal reservoir resulted in the discovery of 3 rodents, psammomys obesus, naturally infected with leishmania. this is of importance as far as prophylactic measures are concerned. | 1983 | 6347415 |
| the vertebral column of diabetic sand rats (psammomys obesus). | intervertebral discs and vertebral spongiosa of diabetic and nondiabetic sand rats were investigated histologically and morphometrically. in diabetic animals, degeneration of the intervertebral discs was accelerated. morphometrically, there was a consistent trend in the diabetics toward an attenuated bone turnover, which was, however, statistically significant only in regard to the length of the trabecular surface covered by osteoblasts. in the vertebral column of the sand rat, the tendency to o ... | 1988 | 3203821 |
| leishmania infecting man and wild animals in saudi arabia. 3. leishmaniasis in psammomys obesus cretzschmar in al-ahsa oasis. | zoonotic cutaneous leishmaniasis (zcl) is hyperenzootic in psammomys obesus in al-ahsa oasis in saudi arabia: 93% of 202 specimens of this rodent examined had signs of the infection. leishmania major and l. arabica were isolated from both normal ear skin as well as from ears with slight to severe lesions. l. major was the predominant species and gave rise to characteristic lesions that consisted of swelling, rounding of the edges, hyperpigmentation, ulceration, necrosis and, in advanced cases, s ... | 1987 | 3306886 |
| ultrastructure of the neuro-insular complexes in the pancreas of sand rats (psammomys obesus). | the ultrastructure of the nervous elements in langerhans islets of psammomys obesus has been studied. a great variety of neural structures present in the islets has been described: neuroganglion-, enterochromaffin- and satellite schwann cells (neuro-insular complexes type i) and cholinergic, adrenergic and peptidergic nerve fibers (neuro-insular complexes type ii) in direct contact with the endocrine cells. in the pericapillary space typical neuro-vasal endings of neurosecretory type have been d ... | 1983 | 6364665 |
| seasonal changes in the metabolic clearance rate of cortisol in the adult male sand rat (psammomys obesus). | metabolic clearance rate (mcr) of cortisol was measured in the adult male sand rat (psammomys obesus) trapped live throughout the year in the region of béni-abbès in the algerian sahara desert. cortisol mcr exhibited marked annual variations which paralleled those of plasma concentrations of cortisol: it was highest in autumn, decreased in winter, rose again in early march, and was minimal in april and june. these data, taken together with previous results, suggest that the production rate of co ... | 1984 | 6365685 |
| [quantitative histological studies of mast cells in the thyroid of sand rats (psammomys obesus) during the development of a mellitus syndrome]. | mast cells in the thyroid glands of sand rats with different disturbances of the carbon hydrate tolerance (reference-, impaired-glucose-tolerance-, and diabetic group) are quantitative-histologically investigated. in the igt-group (impaired glucose tolerance), mast cells are significant increased. however, the number of these cells in the diabetic group decreased significantly. this investigations demonstrate that the mellitus-syndrome is not only a complex neuroendocrine but also a disturbance ... | 1983 | 6370781 |
| quantitative histological and electron microscopical investigations of endocrine organs of sand rats (psammomys obesus) during the development of diabetes mellitus. | | 1984 | 6370922 |
| [chromosomal phylogeny of gerbillidae. iii. species study of the genera tatera, taterillus, psammomys and pachyuromys]. | the karyotypes of six species of gerbillidae (rodentia)--taterillus congicus, tetarillus sp d'oursi, tatera sp cf. nigrita, tatera guineae, psammomys obesus, and pachyuromys duprasi--are described and compared to those of species already studied. many chromosomal homoeologies are demonstrated, as well as the existence of many rearrangements. some genera, e.g., taterillus, have undergone a very complex chromosomal evolution, while others have kept their karyotypes fairly close to that of the comm ... | 1984 | 6372642 |
| morphometric analysis of cancellous bone of young diabetic and non-diabetic sand rats (psammomys obesus). | cancellous vertebral bone of young diabetic sand rats (psammomys obesus) was compared with that of non-diabetic sand rats of the same sex and age. of 5 morphometric diameters, 3--trabecular area, trabecular surface and osteoblastic surface--showed no statistically significant differences between test and control animals. by contrast, the 2 other parameters determined, namely lacunae containing osteoclasts as well as lacunae devoid of osteoclasts were significantly more numerous in diabetics than ... | 1987 | 3311556 |
| the histopathology of naturally-occurring cutaneous leishmaniasis in the reservoir host, psammomys obesus. | ears from infected psammomys obesus, the gerbil reservoir host of leishmania major, were histopathologically studied. the histopathology was a chronic localized infection consisting of an epithelioid granuloma with greatly increased populations of mast cells, melanocytes and melanophores; ulceration was present and parasites were always very few and inside parasitophorus vacuoles. | 1987 | 3326687 |
| hybrid formation within the genus leishmania? | leishmanial organisms isolated from a desert rodent (psammomys obesus) and a feral dog (canis familiaris) in the eastern province of saudi arabia were isoenzymically distinct from leishmania major and l. arabica, organisms usually associated with human and wild animal cutaneous leishmaniasis in this area. further examination of isoenzyme banding patterns of cloned populations of these organisms, together with karyotyping using orthogonal field alternation gel electrophoresis and the use of highl ... | 1987 | 3508260 |
| ultrastructural evidence for the presence of a glial sheath investing the islets of langerhans in the pancreas of mammals. | ultrastructural evidence is presented for a peri-insular glial or schwann cell sheath surrounding islets of langerhans in different mammals. the sheath covers substantial areas of the islet periphery. in the sand rat (psammomys obesus) there are islets where 1/2 to 3/4 of the surface is invested by a virtually continuous glial sheath. usually the sheath covers one of the poles of the islets and is thus differentiated from the peri-insular connective tissue and pancreatic acini. the sheath is com ... | 1984 | 6383622 |
| leishmaniasis in israel: reservoir hosts, sandfly vectors and leishmanial strains in the negev, central arava and along the dead sea. | the reservoir animals, sandfly vectors and strains of leishmania from foci in the southern region of israel were studied. the rodent host species are: psammomys obesus, meriones crassus and probably nesokia indica. the vector species are phlebotomus papatasi, which were caught at all collecting sites and ph. sergenti, which were collected in the area of the dead sea and in the central arava. strains of leishmania major isolated from rodents, vectors and man were serologically and enzymologically ... | 1984 | 6385358 |
| [quantitative histological studies of pancreatic mast cells in sand rats (psammomys obesus) during formation of a mellitus syndrome. 1. the exocrine pancreas]. | | 1984 | 6385518 |
| [quantitative histological studies of pancreatic mast cells in sand rats (psammomys obesus) during formation of a mellitus syndrome. 2. the islands of langerhans]. | | 1984 | 6385519 |
| the diabetic response of weanling sand rats (psammomys obesus) to diets containing different concentrations of salt bush (atriplex halimus). | understanding the sand rat's metabolic responses is necessary in order to employ the animal gainfully in the study of diabetes. weanlings are most susceptible to the effect of diabetogenic diets. in the present experiment, weanling sand rats were fed diets at 3 levels of energy intake. the diets were based on pellets composed of different ratios of salt bush (atriplex halimus) and a standard laboratory animal chow pellet. the results showed a significant correlation between the level of energy i ... | 1986 | 3519049 |