| photosensitization in cattle and sheep caused by feeding ammi majus (greater ammi; bishop's-weed). | feeding ammi majus to cattle and sheep caused photosensitization in both species. it also caused photosensitization in human beings who had dermal contact with the plant and subsequent exposure to sunlight. | 1978 | 564649 |
| photosensitization in sheep fed ammi majus (bishop's weed) seed. | ammi majus (bishop's weed) grows on the coastal region of southern united states and in other parts of the world. this plant causes severe photosensitization in livestock and probably contributes to the severe photosensitization outbreaks seen in texas. sheep were fed finely ground seed of a majus via stomach tube at dose rates of 1, 2, 4, and 8 g/kg of body weight and exposed to sunlight. the single dose of 8 g/kg produced severe clinical signs (in 24 to 48 hours): cloudy cornea, conjunctivoker ... | 1978 | 564651 |
| preliminary studies on the anti-schistosomal effect of ammi majus l. | ammi majus l., a plant belonging to the family umbellifereae was found to possess a certain antischistosomal effect in mice infected with s. mansoni. this was proved by applying two techniques, the worm burden and the oogram change. bergapten, a pure furocoumarin naturally present in ammi majus was found to have certain schistosomicidal effect. | 1978 | 565698 |
| linear furocoumarins (psoralens) from the seed of texas ammi majus l. (bishop's weed). | | 1978 | 730951 |
| ammirin, a new coumarin constituent from ammi majus l. fruits. natural coumarins, part xvi. | | 1975 | 1134590 |
| alloimperatorin from ammi majus fruits. natural coumarins, part xx. | | 1975 | 1134591 |
| acute and chronic manifestations of ammi majus induced photosensitisation in ducks. | the acute and chronic symptoms seen in ducks following ammi majus induced photosensitisation are described. the acute changes were inflammatory in nature whereas the chronic changes included severe deformities of the beak and footwebs, mydriasis and eccentric location of the pupil. | 1975 | 1162869 |
| histology of the iris in geese and ducks photosensitized by ingestion of ammi majus seeds. | geese and ducks were photosensitized by the ingestion of ammi majus seeds, and exposure to sunlight. mydriasis was a characteristic clinical feature of this syndrome in both species. histologically the iris of the affected birds showed vacuolisation and varying degrees of atrophy of the muscle of the sphincter pupillae. the effect of pilocarpine and physostigmine on the normal and mydriatic eyes was studied. the possible mode of action of photosensitization and the significance of these findings ... | 1975 | 1242280 |
| molecular cloning, induction and taxonomic distribution of caffeoyl-coa 3-o-methyltransferase, an enzyme involved in disease resistance. | trans-caffeoyl-coa 3-o-methyltransferase is involved in the reinforcement of the plant cell wall under conditions that trigger the disease resistance response (pakusch, a.-e., kneusel, r.e., and matern, u. (1989) arch. biochem. biophys. 271, 488-494). partial amino acid sequences of the enzyme from cultured parsley cells that had been treated with a crude elicitor were identified (pakusch, a.-e., matern, u., and schiltz, e. (1991) plant physiol. 95, 137-143), and corresponding degenerated oligon ... | 1991 | 1894629 |
| effect of trigonella foenum-graecum and ammi majus on calcium oxalate urolithiasis in rats. | the present study was undertaken to investigate the effect of trigonella foenum-graecum seed and ammi majus fruit on experimentally-induced kidney stones. oxalate urolithiasis in male rats was produced by the addition of 3% glycolic acid to their diet. after 4 weeks, highly significant deposition in the kidneys was noticed and changes in water intake and body weight recorded. daily oral treatment with t. foenum-graecum significantly decreased the quantity of calcium oxalate deposited in the kidn ... | 1989 | 2615405 |
| elicitor-induced biosynthesis of psoralens in ammi majus l. suspension cultures. microsomal conversion of demethylsuberosin into (+)marmesin and psoralen. | suspension cultures of ammi majus l. cells produce various linear furanocoumarins in response to treatment with elicitor preparations from either alternaria carthami chowdhury or phytophthora megasperma f.sp. glycinea. microsomes which were isolated from these cells 14 h after addition of the elicitor efficiently catalyzed the conversion of demethyl [3-14c]suberosin into labelled (+)marmesin in the presence of nadph and oxygen. in contrast to the chemical cyclization of demethylsuberosin by m-ch ... | 1988 | 2828055 |
| biosynthesis of psoralens. psoralen 5-monooxygenase activity from elicitor-treated ammi majus cells. | microsomes prepared from cultured ammi majus cells that had been challenged for 14 h with an elicitor derived from the cell walls of phytophthora megasperma f.sp. glycinea (pmg) converted psoralen to bergaptol (5-hydroxypsoralen) in the presence of nadph and oxygen. the enzymatic activity was characterized as an inducible cytochrome-p-450-dependent monooxygenase associated with the endoplasmic reticulum. all of the steps involved in bergapten (5-methoxypsoralen) biosynthesis in ammi majus have n ... | 1988 | 3181429 |
| separation of ammajin and marmesin from the fruits of ammi majus and their chemical estimation. | | 1973 | 4705799 |
| a study of the active constituents of ammi majus fruits at different stages of maturity. | | 1972 | 5081809 |
| a spectrophotometric method for the estimation of furocoumarin content of the fruits of ammi majus. | | 1972 | 5081821 |
| effect of imperatorin, a toxic principle from ammi majus, on energy-transfer in mitochondria. | | 1968 | 5721660 |
| examples of poisonous plants in israel of importance to animals and man. | several plants causing poisoning in herbivores in israel have an association with human health. ferula communis (giant fennel) contains a potent anticoagulant and induces severe haemorrhagic diathesis in grazing ewes, or similar changes in utero in lambs. these and other teratogenic changes have been seen in babies from mothers receiving the anticoagulant warfarin during pregnancy. the ferula interaction in sheep may be used as a model to study this embryotoxicity in man. ammi majus (bishops wee ... | 1983 | 6578721 |
| ergotism and photosensitization in swine produced by the combined ingestion of claviceps purpurea sclerotia and ammi majus seeds. | poisoning of domestic animals happens frequently in the southeast of buenos aires province (argentina). intoxications are produced mainly by the ingestion of plants and mycotoxins, but animals are rarely affected simultaneously by both types of agents. one herd of pigs suffered simultaneous intoxications by ergot alkaloids from claviceps purpurea sclerotia and furocoumarins from ammi majus seeds. pigs were fed a diet composed of wheat (poor quality) or corn and protein and vitamin supplements. t ... | 1997 | 9087928 |
| antimicrobial screening of some indian spices. | in india, spices have been traditionally used since ancient times, for the preservation of food products as they have been reported to have antiseptic and disinfectant properties. in this respect, a preliminary screening for antimicrobial activities of 35 different indian spices has been carried out. of the spices surveyed, the results indicate that clove, cinnamon, bishop's weed, chilli, horse raddish, cumin, tamarind, black cumin, pomegranate seeds, nutmeg, garlic, onion, tejpat, celery, cambo ... | 1999 | 10548758 |
| establishment of hairy root cultures of ammi majus. | axenically grown ammi majus plantlets were inoculated with seven different agrobacterium rhizogenes strains. hairy root lines were established only after inoculation with the two agropine strains: a4 and lba9402. the growth rate of hairy root cultures was about thirty times faster than that of callus and cell suspension cultures. polymerase chain reaction with primers for the genes rolb and rolc confirmed the integration of the t-dna fragment of ri plasmid of a. rhizogenes to the genome of hairy ... | 2001 | 11164597 |
| functional expression of cinnamate 4-hydroxylase from ammi majus l. | total rna was isolated from dark-grown cell suspension cultures of ammi majus l. that had been induced with fungal elicitor or treated with water for control and used as template with cytochrome p450-specific primers for dd-rt-pcr amplifications. a cdna clone was generated from the elicited transcripts and assigned to cinnamate 4-monooxygenase based on sequence alignments and functional expression in yeast cells. comparison of the translated polypeptide with database accessions of heterologous c ... | 2003 | 12943761 |
| furanocoumarin biosynthesis in ammi majus l. cloning of bergaptol o-methyltransferase. | plants belonging to the apiaceae or rutaceae accumulate methoxylated psoralens, such as bergapten or xanthotoxin, as the final products of their furanocoumarin biosynthesis, and the rate of accumulation depends on environmental and other cues. distinct o-methyltransferase activities had been reported to methylate bergaptol to bergapten and xanthotoxol to xanthotoxin, from induced cell cultures of ruta graveolens, petroselinum crispum and ammi majus. bergaptol 5-o-methyltransferase (bmt) cdna was ... | 2004 | 15009205 |
| cations modulate the substrate specificity of bifunctional class i o-methyltransferase from ammi majus. | caffeoyl-coenzyme a o-methyltransferase cdna was cloned from dark-grown ammi majus l. (apiaceae) cells treated with a crude fungal elicitor and the open reading frame was expressed in escherichia coli. the translated polypeptide of 27.1-kda shared significant identity to other members of this highly conserved class of proteins and was 98.8% identical to the corresponding o-methyltransferase from parsley. for biochemical characterization, the recombinant enzyme could be purified to apparent homog ... | 2004 | 15556611 |
| investigation on the phenolics of some spices having pharmacotherapeuthic properties. | spices are an important group of agricultural commodities being used by many civilizations all over the world to aid flavor, taste and nutritional values in the food. in traditional medical systems, their ability to heal various physical, mental and emotional problems has widely been reported. with this view, hplc analysis was performed to estimate phenolic acids in 21 spices (asafetida, bishop's weed, black mustard, coriander, cinnamon, clove, curry leaf, cumin black, cumin, fennel, fenugreek, ... | 2004 | 15927923 |
| molecular cloning and functional characterization of psoralen synthase, the first committed monooxygenase of furanocoumarin biosynthesis. | ammi majus l. accumulates linear furanocoumarins by cytochrome p450 (cyp)-dependent conversion of 6-prenylumbelliferone via (+)-marmesin to psoralen. relevant activities, i.e. psoralen synthase, are induced rapidly from negligible background levels upon elicitation of a. majus cultures with transient maxima at 9-10 h and were recovered in labile microsomes. expressed sequence tags were cloned from elicited ammi cells by a nested dd-rt-pcr strategy with cyp-specific primers, and full-size cdnas w ... | 2007 | 17068340 |
| isolation and functional characterization of cyp71aj4 encoding for the first p450 monooxygenase of angular furanocoumarin biosynthesis. | the biosynthesis of linear and angular furanocoumarins is still poorly understood at the molecular level, with only psoralen synthase (cyp71aj1) identified from ammi majus. using cdna probes inferred from cyp71aj1, three orthologs were isolated from apium graveolens (cyp71aj2) and pastinaca sativa (cyp71aj3 and -4) and functionally expressed in yeast cells. cyp71aj2 and cyp71aj3 displayed psoralen synthase activity, whereas cyp71aj4 only catalyzed the conversion of (+)-columbianetin to angelicin ... | 2009 | 19098286 |
| in vitro isolation, elicitation of psoralen in callus cultures of psoralea corylifolia and cloning of psoralen synthase gene. | psoralen, an important furanocoumarin occurring abundantly in seeds of psoralea corylifolia is used as an anticancerous compound against leukemia and other cancer cell lines. evaluation and isolation of psoralen from the calluses derived from different plant parts, viz. cotyledons, nodes, leaves and roots have been done in the present case for the first time. amongst all, a maximum of 1934.75 μg/g f.w. of psoralen was recorded in callus derived from cotyledons, followed by 1875.50 and 1465.75 μg ... | 2011 | 21524916 |
| observations on in vitro and in vivo antimicrofilarial effects of bishop's weed (trachispermum ammi). | the antimicrofilarial efficacy of trachispermum ammi extacts in vitro and in vivo using setaria cervi as a model, was investigated. t. ammi seed extracts were prepared using different solvents (with increasing order of polarity of the solvent) including petroleum ether, diethyl ether, chloroform, ethyl acetate, acetone, ethanol, and methanol. the extracts were tested for in vitro antimicrofilarial activity. the ethanolic and the methanolic extracts showed maximum activity in causing flaccidity i ... | 2011 | 23543135 |
| cloning, functional characterization, and catalytic mechanism of a bergaptol o-methyltransferase from peucedanum praeruptorum dunn. | coumarins are main active components of peucedanum praeruptorum dunn. among them, methoxylated coumarin compound, such as bergapten, xanthotoxin, and isopimpinellin, has high officinal value and plays an important role in medicinal field. however, major issues associated with the biosynthesis mechanism of coumarins remain unsolved and no corresponding enzyme has been cloned from p. praeruptorum. in this study, a local blastn program was conducted to find the candidate genes from p. praeruptorum ... | 2016 | 27252733 |
| evaluation of antibacterial activity of crude protein extracts from seeds of six different medical plants against standard bacterial strains. | a huge group of natural antimicrobial compounds are active against a large spectrum of bacterial strains causing infectious threat. the present study was conducted to investigate the crude extracts of antimicrobial protein and peptide efficacy from six medicinal plant seeds. extraction was carried out in sodium phosphate citrate buffer, and sodium acetate buffer using different ph. antimicrobial activities of these plants were determined by the microbiological technique using agar well diffusion ... | 2014 | 24600307 |
| coexpression of cpr from various origins enhances biotransformation activity of human cyps in s. pombe. | cytochrome p450 enzymes (cyps or p450s) are the most important enzymes involved in the phase i metabolism of drugs (and other xenobiotics) in humans, and the corresponding drug metabolites are needed as reference substances for their structural confirmation and for pharmacological or toxicological characterization. we have previously shown that biotechnological synthesis of such metabolites is feasible by whole-cell biotransformation with human cyps recombinantly expressed in the fission yeast s ... | 2013 | 23737303 |
| cytotoxic new furoquinoline alkaloid isolated from ammi majus l. growing in egypt. | two alkaloids of the furoquinoline-type were isolated from ammi majus l.; a new one and was identified as 4-hydro-7-hydroxy-8-methoxyfuroquinoline (1), and the other was isolated for the second time from nature and was identified as 4-hydro-7-hydroxy-8-prenyloxyfuroquinoline (2). the structures of the isolated compounds were established and confirmed by 1d and 2d nmr spectroscopy including (1)h, (13)c nmr, cosy, hsqc and hmbc, while the exact masses were confirmed by hresi/ms. the cytotoxic acti ... | 2017 | 27686420 |
| xanthotoxin prevents bone loss in ovariectomized mice through the inhibition of rankl-induced osteoclastogenesis. | xanthotoxin (xat) is extracted from the seeds of ammi majus. here, we reported that xat has an inhibitory effect on osteoclastogenesis in vitro through the suppression of both receptor activator of nuclear factor-κb ligand (rankl)-induced ros generation and ca(2+) oscillations. in vivo studies showed that xat treatment decreases the osteoclast number, prevents bone loss, and restores bone strength in ovariectomized mice. | 2016 | 26809192 |
| isolation of methoxyfuranocoumarins from ammi majus by centrifugal partition chromatography. | pure methoxyfuranocoumarins were isolated from ammi majus l. by use of low-pressure column chromatography (lpcc) followed by centrifugal partition chromatography (cpc). the concentrated petroleum ether extract from fruits of a. majus was fractionated on a silica gel column using a gradient of ethyl acetate in dichloromethane (0-80%, v/v). coumarin-rich fractions were analyzed by thin-layer chromatography (tlc) and high-performance liquid chromatography with diode array detection (hplc/dad). xant ... | 2016 | 26209576 |
| herbal tea extracts inhibit cytochrome p450 3a4 in vitro. | ciclosporin and sirolimus, two immunosuppressive agents with narrow therapeutic windows, are mainly metabolized by cytochrome 3a4 (cyp3a4). a clinical case of toxic blood levels of these drugs after the consumption of a '24-flavours' tea was reported. this study aims to identify the causative ingredients of the 24-flavour herbal tea in the inhibition of cyp3a4 metabolism. | 2014 | 24824478 |
| predator-prey relationships on apiaceae at an organic farm. | orius insidiosus (say) and o. pumilio (champion) were confirmed to be sympatric in north central florida as the major predators of the florida flower thrips, frankliniella bispinosa (morgan), on flowers of queen anne's lace, daucus carota l. and false queen anne's lace, ammi majus l. f. bispinosa was the predominant thrips observed on both flowers but colonized d. carota to a greater extent and earlier in the season than a. majus. despite differences in the abundance of f. bispinosa on the two p ... | 2012 | 22732606 |
| evaluation of the antihyperlipidemic, anti-inflammatory, analgesic, and antipyretic activities of ethanolic extract of ammi majus seeds in albino rats and mice. | pharmacological and biochemical studies on the ammi majus seeds l. (family umbelliferae) grown in egypt are limited. furocoumarins are the major constituents in the plant seeds. in the present study, the evaluation of the antihyperlipidemic, anti-inflammatory, analgesic, and antipyretic activities on albino rats and mice was done. after 2 months of administration, both the doses (50 and 100 mg/kg body weight [bwt], respectively) of the alcoholic extract of the a. majus seed result in a significa ... | 2012 | 22550046 |
| effect of medicinal and aromatic plants on rumen fermentation, protozoa population and methanogenesis in vitro. | the potential of tannins from 21 medicinal and aromatic plant leaves as antimethanogenic additives in ruminant feeds was investigated. the effect of tannin from these leaves on rumen fermentation parameters, protozoa population and methanogenesis was studied by incubating the samples [200 mg dry matter (dm)] without and with polyethylene glycol (peg)-6000 (400 mg dm) as a tannin binder during 24-h incubation in the in vitro hohenheim gas method. based on the methane percentage estimated in the t ... | 2013 | 22385477 |
| anti-inflammatory new coumarin from the ammi majus l. | investigation of the aerial parts of the egyptian medicinal plant ammi majus l. led to isolation of new coumarin, 6-hydroxy-7-methoxy-4 methyl coumarin (2) and 6-hydroxy-7-methoxy coumarin (3); this is the first time they have been isolated from this plant. the structures of the compounds (2 &3) were elucidated by spectroscopic data interpretation and showed anti-inflammatory and anti-viral activity. graphical an efficient, one-new coumarin (2) was isolated from the aerial parts of the a. majus ... | 2012 | 22373472 |
| molecular evolution of flavonoid dioxygenases in the family apiaceae. | plant species of the family apiaceae are known to accumulate flavonoids mainly in the form of flavones and flavonols. three 2-oxoglutarate-dependent dioxygenases, flavone synthase or flavanone 3 beta-hydroxylase and flavonol synthase are involved in the biosynthesis of these secondary metabolites. the corresponding genes were cloned recently from parsley (petroselinum crispum) leaves. flavone synthase i appears to be confined to the apiaceae, and the unique occurrence as well as its high sequenc ... | 2005 | 15913674 |
| coumarin compounds in ammi majus l. callus cultures. | callus cultures of ammi majus l. (bishop's weed), apiaceae, were maintained on variants of linsmaier-skoog's (l-s) medium differing in the content of the phytohormones, alpha-naphthaleneacetic acid (naa) and 6-benzylaminopurine (bap) (0.1-10.0 mg/l). the increments of callus tissue fresh weight showed considerable differences (1.4 bis 4.4-fold) during 4-week subcultures on the media tested. hplc analysis revealed the presence of six compounds in the extracts of callus tissues, which are known me ... | 2000 | 11031774 |
| occupational allergic rhinitis and contact urticaria caused by bishop's weed (ammi majus). | bishop's weed (ammi majus) has been known to induce toxic phytophotodermatitis. we now describe ige-mediated rhinitis and contact urticaria caused by exposure to bishop's weed in a 31-year-old atopic female florist. a skin prick-prick test with bishop's weed flowers gave an 8-mm wheal, and the bishop's weed-specific ige level in the patient's serum was 9.7 pru/ml (rast class 3). in an immunoblotting experiment with the patient's serum, nine ige-binding protein bands with the molecular weights 19 ... | 1999 | 10435481 |
| psoralen photobiology and photochemotherapy: 50 years of science and medicine. | in 1998 it is appropriate to commemorate the 50th anniversary of el mofty's use of purified 8-methoxypsoralen (8-mop) in the treatment of vitiligo (el mofty am. a preliminary clinical report on the treatment of leukoderma with ammi majus linn. j r egypt med assn 1948,31:651 65. el mofty am, el sawalhy h, el mofty m. clinical study of a new preparation of 8-methoxypsoralen in photochemotherapy. int j dermatol 1994;8:588 92). two young american dermatologists (aaron lerner and thomas fitzpatrick) ... | 1999 | 10098699 |
| acetylated flavonol triglycosides from ammi majus l. | two new acetylated flavonol triglycosides: kaempferol and isorhamnetin 3-o-[2"-(4"'-acetylrhamnosyl)-6"-glucosyl] glucosides, were isolated and identified from the aerial parts of ammi majus l. in addition, three known flavonol glycosides namely; isorhamnetin-3-o-rutinoside, kaempferol-3-o-glucoside and isorhamnetin-3-o-glucoside were detected. | 1998 | 9883598 |
| new possible molluscicides from calendula micrantha officinalis and ammi majus. ii. molluscicidal, physiological, and egg-laying effects against biomphalaria alexandrina and bulinus truncatus. | in the present study, the effects of cuso4 and crude extracts of the different parts of calendula micrantha officinalis and ammi majus, i. e., leaves, stems, roots, and flowers, on adult biomphalaria alexandrina and bulinus truncatus were investigated. generally, leaves and flowers of both plants exhibited marked potency in killing the snail vectors of schistosomiasis. the recorded lc50 and lc90 values showed that c. officinalis was more toxic to both snails than a. majus, and b. truncatus are m ... | 1996 | 9007003 |
| physico-chemical profile of ammi majus. | whole part and mother tincture of ammi majus were chemically analyzed for setting the standards in homoeopathic system of medicine. extractive value, ash value, tlc uv study and the absorbance spectra in the range of 200-500 nm can be taken as parameters to fix standards. | 1996 | 22556783 |
| enhanced xanthotoxin content in regenerating cultures of ammi majus and micropropagation. | since in ammi majus the seed set and germination is poor attempts were made to propagate the plants through tissue cultures and monitor the yield of xanthotoxin (furanocoumarin) in the resultant callus and plantlets. the callus from cotyledonary leaves obtained on ms medium supplemented with alpha-indoleacetic acid (iaa) + kinetin (kn) + casein hydrolysate (ch), differentiated shoots in 100 % cultures when adenine was added to the above medium. plantlets resulted on ms medium with indolebutyric ... | 1995 | 17238101 |
| coumarins and other phenylpropanoid compounds in the defense response of plant cells. | cultured cells of the apiaceae, e. g. petroselinum crispum and ammi majus, produce large quantities of coumarin phytoalexins upon treatment with fungal elicitors and concomitantly reinforce their cell walls by ferulic ester incorporation. in these reactions, the cells mimic the disease resistance response commonly expressed in plants following infection by phytopathogenic fungi. both coumarins and ferulic esters are derived from the general phenylpropanoid pathway. the elicited apiaceae cell cul ... | 1991 | 17226218 |
| [phototoxic dermatitis following the use of ammi majus fruit for vitiligo]. | the injudicious use of a systemically administered herb containing psoralens derived from the fruits of ammi majus in combination with exposure of the skin to the sun caused a severe phototoxic dermatitis in a moroccan patient with vitiligo. she was disappointed in the treatment by the dermatologist. a family member advised her to start the treatment with herbs. the identification of the herbs by microscopic, chromatographic and biological techniques demonstrated that they contained the linear f ... | 1991 | 2023655 |
| induction of two prenyltransferases for the accumulation of coumarin phytoalexins in elicitor-treated ammi majus cell suspension cultures. | two dimethylallyl diphosphate:umbelliferone dimethylallyltransferase (prenyltransferase) activities, catalysing the 6-prenylation and the 7-o-prenylation, respectively, of umbelliferone in the course of phytoalexin synthesis, increased in ammi majus cell suspension cultures in response to elicitor treatment. both enzyme activities were dependent on mg2+ or mn2+ with significant preference for mg2+ in the 6-prenylation reaction. whereas dark-grown cells did not contain these activities, both pren ... | 1990 | 1366425 |
| phytophotodermatitis. | several plant families contain species liable to cause phytophotodermatitis. they include the umbelliferae of which ammi majus has been known for centuries and the rutacea to which citrus bergamia belongs. phototoxic plants are also found in, e.g., the moraceae, leguminosae, rosaceae and compositae plant families. the photoreactivity of the plants depends on their furocoumarins (psoralens) content. these cause skin damage by phototoxic mechanisms, when activated by longwave ultraviolet radiation ... | 1984 | 6397734 |
| highly potent germination inhibitors in aqueous eluate of fruits of bishop's weed (ammi majus l.) and avoidance of autoinhibition. | the aqueous eluate from fruits ofammi majus (bishop's weed, umbelliferae) remarkably inhibited germination of adjacent seeds ofanastatica hierochuntica, lettuce, or tomato but had no effect on intact fruits ofammi. similar inhibition was found in dark or in light, except that seeds ofa. hierochuntica were significantly more inhibited in the dark than in the light. xanthotoxin was isolated, identified, and found to account for about a sixth of the inhibitory activity of the eluate. after fruits o ... | 1982 | 24414584 |
| thin-layer chromatographic - spectrophotometric determination of methoxsalen (xanthotoxin) in ammi majus seed. | | 1977 | 562630 |
| [anatomical and histochemical study of bishop's-weed (ammi majus l.)]. | | 2014 | 1218616 |
| eye lesions in ducklings fed ammi majus seeds. | | 1975 | 813450 |
| chronic lesions in geese photosensitized by ammi majus. | chronic lesions of the beak, footweb, and eye of geese photosensitized by the comsumption of ammi majus (l.) are described, 7 weeks after the acute symptoms commenced. sixty-four (48%) of the 133 birds in the flock showed various degrees of abnormality. all affected birds had stunting of the upper beak and cicatrization and thickening of the footweb. eighty-nine percent of the affected birds showed ocular involvement, comprising chemosis, blepharoconjunctivitis, keratitis, symblepharon, ankylobl ... | 2003 | 1200953 |
| the comparative photosensitizing properties of ammi majus and ammi visnaga in goslings. | | 2003 | 4433298 |
| observations on the experimental poisoning of young geese with ammi majus. | the plant ammi majus (l.) was fed to 2 groups of young geese in an attempt to reproduce a field condition resembling photo-sensitization. the group exposed to sunlight developed skin lesions on the footweb and beak, whereas the group housed indoors appeared normal, together with the control group, which was not fed the plant but was exposed to sunlight. blood was taken 29 d after commencement of the feeding trial, and rises in serum enzyme levels of lactic dehydrogenase, glutamic oxaloacetic tra ... | 1974 | 18777263 |
| [comparative anatomical study of the structure of the fruit of ammi visnaga l. and ammi majus l]. | | 2013 | 4774711 |
| natural coumarins. xii. umbelliprenin, a constituent of ammi majus l. fruits. | | 1971 | 5125784 |
| estimation of xanthotoxin, imperatorin and bergapten in ammi majus fruits and formulations. | | 1970 | 5428499 |
| natural coumarins. xi. the distribution of coumarins in the ammi majus l. plant and a possible pattern for their biogenetic evolution. | | 1970 | 5441610 |
| isolation of isopimpinellin from the fruits of ammi majus l. natural coumarins. iv. | | 1966 | 4295763 |
| [on the trial cultivation of ammi majus l. ii]. | | 1966 | 6008584 |
| [trial cultivation of ammi majus l]. | | 1965 | 5896385 |
| [qualitative and quantitative changes in the furocoumarin content in ammi majus l. in the course of vegetation]. | | 1965 | 5898849 |
| [quantitative determination of the active substances in the seeds of ammi majus l]. | | 1963 | 14109902 |
| [separation of furocoumarins from the seeds of ammi majus l. by paper chromatography]. | | 1963 | 14086929 |
| [isolation of xanthotoxin and marmesine from ammi majus l. fruits]. | | 1963 | 14059259 |
| [treatment of patients with vitiligo with extracts of ammi majus (on the 70th birthday of prof. gavalovskii)]. | | 1961 | 13787646 |
| 8-methoxypsoralen-a short review and comment. | 8-methoxypsoralen is a purified extract of the root ammi majus lynn, which was used in a crude form for centuries in the middle east in the treatment of various skin diseases. in recent years it has been found that the purified extract, when taken internally, increases all skin responses to sunlight, including tanning. when too much drug is taken or when the patient is exposed to sunlight too long, the preliminary erythema may be painful, and blistering may occur. in some patients with vitiligo, ... | 1960 | 18732266 |
| [chromatographic separation & identification of the crystallin constituents of ammi majus with the aid of a single phase current medium]. | | 1959 | 13670616 |
| ammi majus. | | 1958 | 17816855 |
| ammi majus. | | 1958 | 17816854 |
| [ammi majus & skin darkening]. | | 1958 | 13625209 |
| ammi majus linn in the treatment of vitiligo. | | 1957 | 13421715 |
| [first experimental application of ammi majus l. extract prepared in poland, in the treatment of vitiligo]. | | 2006 | 13465858 |
| [active principles of ammi majus, a new therapeutic agent for leukoderma]. | | 1955 | 13244448 |
| treatment of vitiligo with extracts of ammi majus linn. | | 1955 | 14392340 |
| leucoderma and its treatment with ammi majus. | | 1955 | 14392339 |
| [preliminary report on the treatment of vitiligo with ammi majus]. | | 2007 | 13341768 |
| [treatment of complete baldness by ammi majus extracts]. | | 1955 | 14371545 |
| ammoidin (xanthotoxin) in the treatment of vitiligo. | eighteen patients with vitiligo were treated with two crystalline substances, xanthotoxin (ammoidin) and imperatorin (ammidin) from the plant ammi majus. four patients improved more than 50 per cent. one had complete cure, but depigmentation recurred after a few months. six patients had moderate improvement (less than 50 per cent), three had slight repigmentation, and in five cases there was no improvement. these results are similar to those reported by other investigators.pronounced local infla ... | 1954 | 13209374 |
| [the ammi majus indigenous to the treatment of vitiligo]. | | 1954 | 13194534 |
| [vitiligo: its treatment with ammi majus]. | | 1954 | 13161656 |
| [treatment of vitiligo with ammi majus: preliminary note]. | | 1954 | 13180425 |
| [on the treatment of vitiligo with ammi majus]. | | 1954 | 13180421 |
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