| antibiotics produced by streptomyces olivaceus 142. ii. isolation, purification and activity spectrum of antibiotic wr 142-fpg. | a method of isolating antibiotic wr 142-fpg from the fermentation broth and mycelium of mutant fpg of the strain streptomyces olivaceus 142 has been developed. the method of purification of the active substance and activity spectrum agains microorganisms are described. some of the basic properties of two preparations are given: a) the preparation designed i, partly purified, containing a peptide moetye and b) the preparation designed ii, which is a homogeneous chromatographically preparation wit ... | 1977 | 326221 |
| [metabolic products of microorganisms 183, imacidin, a new peptid antibiotic from streptomyces olivaceus (author's transl)]. | streptomyces olivaceus, strain tü 1379 produces beside the red dyestuff prodigiosin several closely related hitherto unknown cyclodepsipeptide antibiotics, mainly imacidine b and c and imacidinic acids. the antibiotics affect murein biosynthesis. only actinomycetes are inhibited. | 1979 | 543774 |
| [study of cysteine-deficient actinomyces olivaceus v kx mutants]. | | 1977 | 904486 |
| [study of the porphyrin content in mutants of actinomyces olivaceus v kx met- (b12-)]. | | 1975 | 1214631 |
| [effect of delta-aminolevulinic acid on the biosynthesis of porphyrins and vitamin b12 by suspensions of starved cells of actinomyces olivaceus v kx met- (b12-) mutants]. | | 1975 | 1214638 |
| [formation of acetoin by actinomyces olivaceus cultures]. | actinomyces olivaceus and some other actinomycetes accumulate acetoin and 2,3-butanediol in the cultural broth. addition of cobalt to the medium favours the accumulation of acetoin. | 1975 | 1160632 |
| [fertility of streptomyces olivaceus v kx]. | | 1977 | 865304 |
| [the effect of dna isolated from different sources and different physico-chemical conditions on candida tropicalis strain d-2 his-]. | mutagenic effect of dna, isolated from escherichia coli, actinomyces olivaceus and calf thymus, on hystidine-deficient strain of candida tropicalis d-2 is demonstrated. | 1975 | 773761 |
| influence of phosphorus on the composition of polar lipids of actinomyces olivaceus. | the influence of phosphorus on the composition of the lipids of act. olivaceus was studied. it was found that the phosphorus content in the culture medium can serve as a regulator of the synthesis of definite lipids. in the presence of a phosphorus deficiency in the medium (0.0006 g/100 ml), not only the ratio of the polar and neutral fractions, but also the composition of the polar lipids changes, namely: the content of cardiolipin and phosphatidylinositol mannoside is decreased; the content of ... | 1978 | 743498 |
| d-lyxose as a substrate for streptomyces d-xylose isomerase. | results are presented which show that the d-xylose isomerases present in streptomyces olivaceus and streptomyces phaeochromogenes nrrl b-3559 are incapable of utilizing d-lyxose as a substrate. the implications of these findings as related to the use of d-lyxose in the selection of constitutive mutants are discussed. | 1978 | 736548 |
| [the recombination capacity of uvs mutants of streptomyces olivaceus vkx]. | the frequency of genetic recombination (with allowance for the fertility system action) has been studied in crosses of 7 different uvs mutants with two uvs+ strains (ant+ and ant-) and one specially constructed uvs strain. it is shown that mutation uvs, inducing the highest level of sensitivity to uv-light, belongs to the rec-type mutations. | 1988 | 3232203 |
| [the nature of the uvs mutations of streptomyces olivaceus vkx strain 22c supersensitive to uv light]. | | 1988 | 3249570 |
| [effect of phosphorus on the polar lipid makeup of actinomyces olivaceus]. | | 1978 | 641259 |
| antibiotics produced by streptomyces olivaceus 142. iii. influence of antibiotic wr 142 fpg on development of transplantable tumors in mice. | the action of two preparations (i and ii) of antibiotic wr 142 fpg on development of ehrlich carcinoma, nemeth-kellner lymphoma and leukemias l 1210 and p 388 was studied. preparation i injected s.c. daily during 14 days in doses of 10 mg/kg (1/25 ld50) inhibited growth of ehrlich carcinoma and nemeth-kellner lymphoma subcutaneous tumors in r 3 mice by about 70%. the same preparation in a single i.p. injection (10 mg/kg) in fdf1 mice distinctly prolonged survival of mice inoculated with l 1210 l ... | 1977 | 565628 |
| [the photoreactivation capacity of uvs+ and uvs-strains of streptomyces olivaceus vkx]. | | 1985 | 3916950 |
| fermentative production of cobalamin by streptomyces olivaceus. | | 1977 | 548700 |
| experimental extrinsic allergic alveolitis induced in the guinea-pig with streptomyces olivaceus. | | 1974 | 4207504 |
| lipids of streptomyces olivaceus. | | 1966 | 4227372 |
| [uv-sensitive mutants of streptomyces olivaceus vkx]. | 14 uv-sensitive (uvs) mutants of s. olivaceus vkx isolated by replica-plating technique among 45780 survivors after the induction of mutations nitrosoguanidine or uv (about 0.03%). the sensitivity of uvs-mutants to uv-irradiation was 5-10 times higher than in the initial strains and in 4 uvs-mutants it was 100 and more times higher. one of the mutants was supersensitive to uv radiation. | 1979 | 516163 |
| mapping the chromosome of actinomyces olivaceus v kx by heteroclone analysis. | | 1974 | 4445904 |
| heteroclones of actinomyces olivaceus v kx. | | 1974 | 4439045 |
| structures of olivanic acid derivatives mm 22380, mm 22381, mm 22382 and mm 22383; four new antibiotics isolated from streptomyces olivaceus. | | 1979 | 511786 |
| [lipid makeup of actinomyces olivaceus]. | | 1976 | 1026740 |
| [separation of actinomyces olivaceus vkx spores in a saccharose density gradient]. | | 1972 | 4663478 |
| olivanic acids, a family of beta-lactam antibiotics with beta-lactamase inhibitory properties produced by streptomyces species. ii. isolation and characterisation of the olivanic acids mm 4550, mm 13902 and mm 17880 from streptomyces olivaceus. | the olivanic acids mm 4550, mm 13902 and mm 17880 are members of a new family of beta-lactam antibiotics. an isolation and purification process utilising ion-par extraction and ion-exchange chromatography is described and the metabolites are characterised by physico-chemical and biological properties. | 1979 | 468716 |
| [biosynthesis of purines in actinomyces olivaceus v kx. ii. study of the products of purine metabolism]. | | 1974 | 4465647 |
| [analogs of purine bases and purine metabolism in actinomyces olivaceus v kx]. | | 1974 | 4465670 |
| olivanic acids, a family of beta-lactam antibiotics with beta-lactamase inhibitory properties produced by streptomyces species. i. detection, properties and fermentation studies. | the screening of soil actinomyces for beta-lactamase inhibitors is described. using a plate test a number of strains of streptomyces were found to produce beta-lactamase inhibitory activity designated olivanic acid complex. factors affecting the production of this complex by streptomyces olivaceus atcc 21379 are reported. the complex showed antibacterial activity and also inhibited a number of different types of beta-lactamase in a progressive manner. certain ampicillin-resistant bacteria are re ... | 1979 | 468715 |
| [dna synthesis in the dynamics of the germination of spores of actinomyces olivaceus v kx]. | | 1973 | 4791357 |
| antibiotics produced by streptomyces olivaceus 142. antifungal properties of antibiotic wr-142 fpg. | antifungal activity of antibiotic wr-142 fpg was evaluated in vitro and in vivo. in vitro, the minimal inhibitory concentration (mic) for candida and rhodotorula was 0.1 microgram/ml (preparation i) and 0.003 microgram/ml (preparation ii). in vivo, experiments were carried out with model of subacute candidiasis in balb mice. the criteria for antifungal activity of wr-142 fpg were based on survival time of infected animals and numbers of live c. albicans cells in the kidneys and spleen of animals ... | 1979 | 383040 |
| [purine biosynthesis in actinomyces olivaceus v kx. i. steps in the biosynthesis of inosinic acid]. | | 1974 | 4840328 |
| streptomyces olivaceus 142.i. identification of the strain and conditions of antibiotic production. | | 1967 | 4875407 |
| [hydroxylation of reichstein's compound s in the 6 beta and 11 beta positions by streptomyces olivaceus (waksman) waksman and henrici]. | | 1968 | 5264775 |
| [lipoamino acids in the composition of actinomycete polar lipids]. | the capacity for substitution of phospholipids, in particular phosphatidyl ethanolamine, by a phosphorus-lacking lipoamino acid was studied in different groups of actinomycetes. in the conditions of phosphorus deficiency, most cultures were found to be capable of synthesizing a phosphorus-lacking nitrogen-containing lipoamino acid. its characteristics (rf) in tlc are similar to those of ornithinolipid. this fact confirms, for the first time and for different groups of actinomycetes, the hypothes ... | 1979 | 116114 |
| [the effect of delta-alk on the biosynthesis of cobamides and porphyrins by a culture of actinomyces olivaceus]. | | 1969 | 5371802 |
| biosynthesis of a alpha-amylase and protease by streptomyces olivaceus 142. iii. some aspects of alpha-amylase induction. | the induction of alpha-amylase in streptomyces olivaceus 142 depends on the phase of growth of culture and the nature of the carbon sources upon which the cells were grown prior to exposure to inducer. the most susceptible to induction are cells from the initial hours of growth and glycerol -- grown cells. reduction in the susceptibility of cells to alpha-amylase induction is probably a result of catabolic repression. | 1977 | 67765 |
| biosynthesis of alpha-amylase and protease by streptomyces olivaceus 142. ii. biosynthesis of protease. | streptomyces olivaceus 142 produces proteolytic enzymes de novo, mainly in the stationary phase of growth. the highest activity of the enzymes was observed in media containing maltose or fructose. in media supplemented with glucose, glycerol or starch the activity was lower. the synthesis of proteases is subject to catabolic repression. the proteolytic activity is reduced by phosphate buffer. | 1977 | 67764 |
| a cobalt-free corrinoid compound in streptomyces olivaceus. | | 1970 | 5438292 |
| biosynthesis of alpha-amylase and protease by streptomyces olivaceus 142. i. regulation of alpha-amylase activity. | streptomyces olivaceus 142 produces amylase in the logarithmic phase of growth of the culture. the synthesis of the enzyme is induced by maltose and starch. in the case of maltose the synthesis is induced by a contaminating compound, probably being a higher than maltose polymer of glucose. the synthesis of amylase is negatively controlled by catabolic repression. the level of the activity of the enzyme depends not only on the biosynthesis but also on it proteolytic degradation. | 1977 | 67763 |
| [changes in nucleotide composition in dna of actinomyces olivaceus v kx in vitro under effect of nitrosoguanidine and nitrosomethylurea]. | | 1970 | 5519058 |
| antibiotics produced by streptomyces olivaceus 142. i. characterization of the fpg mutant and conditions of production of antibiotic wr 142-fpg. | by treating the streptomyces olivaceus 142 strain simultaneously with ethyleneimine and uv radiation, the fpg mutant was isolated, which was characterized by the fact that in submerged cultures it produces a cytotoxic substance for fibroblasts and tumor cells and inhibits growth of pathogenic fungi. the mutant differs from other strains not only in having a different spectrum of antimicrobial activity, but also by taxonomic properties such as color of the aerial mycelium, liquefaction of gelatin ... | 1976 | 13763 |
| production of desferrioxamine e and new analogues by directed fermentation and feeding fermentation. | streptomyces olivaceus tu 2718 produces the siderophore desferrioxamine e. production depends on l-lysine and iron concentrations in the medium. with optimized conditions the yield of desferrioxamine e could be increased to 12 g/l in feeding fermentations. supplementation of the basic production medium with natural and synthetic precursors of desferrioxamine e led to the production of twelve new analogues of desferrioxamine e. | 1990 | 1367428 |
| [the use of inorganic precursors of cysteine synthesis in the study of cysteine-deficient mutants of actinomyces olivaceus v kx]. | | 1975 | 1214652 |
| [composition of lipids of actinomyces olivaceus--synthesis of vitamin b 12]. | total cellular lipids of the synthetic of vitamin b12 act. olivaceus involve predominantly phospholipids (about 70%). lipid phosphates consist of phosphatidyl ethanol amine and phosphatidyl-2,3-butandiol (over 40 and 30%, respectively) and lower quantities of phosphatidyl inositol olmonomanoside and cardiolipin. the neutral fraction includes the predominating fraction of triglycerides (over 20%) as well as mono- and diglycerides, free fatty acids, hydrocarbons and three fractions similar to waxe ... | 1975 | 1208385 |
| novel and potent gastrin and brain cholecystokinin antagonists from streptomyces olivaceus. taxonomy, fermentation, isolation, chemical conversions, and physico-chemical and biochemical properties. | the discovery and physico-chemical characterization of three novel and minor virginiamycin m1 analogs as potent gastrin antagonists from a culture of a strain of streptomyces olivaceus are described. these analogs are l-156,586, l-156,587 and l-156,588. they are, respectively, 15-dihydro-13,14-anhydro-, 13,14-anhydro- and 13-desoxy-analogs of virginiamycin m1. we also chemically converted virginiamycin m1 (via l-156,587) to l-156,586 and its unnatural epimer, l-156,906. these analogs are competi ... | 1991 | 1906451 |
| [ultrastructure of pili on spore surface in streptomyces olivaceus v kx]. | | 1976 | 1004283 |
| [enzymes involved in the metabolism of flavin nucleotides in streptomyces olivaceus]. | the work was aimed at studying enzymes involved in the metabolism of flavin nucleotides, namely, riboflavin kinase (ec 2.7.1.26) and fad pyrophosphorylase (ec 2.7.7.2), as well as flavin mononucleotide hydrolysis by acid phosphatase (ec 3.1.3.2) and alkaline phosphatase (ec 3.1.3.1) in streptomyces olivaceus actively producing vitamin b12. no correlation could be established between changes in the activity of the above enzymes during the culture growth and the qualitative composition of flavins. ... | 1989 | 2548068 |
| [interspecific recombination of streptomyces coelicolor a 585 scp1 scp2+ and streptomyces olivaceus 24-14 pso1+ and 24-141 pso1]]. | | 1983 | 6400784 |
| [the effect of gamma-radiation, nitrosoguanidine and mitomycin c on uvs+ and uvs-strains of streptomyces olivaceus vkx]. | | 1984 | 6443864 |
| [microbial hydroxylation of estratrienes]. | incubation of the synthetic estrogen 17alpha-ethinyl-estradiol-3-methylether (mestranol) with cultures of penicillium chrysogenum gave 6alpha-hydroxy-17alpha-ethinylestradiol-3-methylether and 6beta-hydroxy-17alpha-ethinylestradiol-3-methylether. the corresponding 3-demethylated compound, 17alpha-ethinylestradiol, gave the 6alpha- and 6beta-hydroxy derivatives in lower yields. if the 6-hydroxy compounds were incubated, they were partially isomerized to a mixture of the 6alpha- and 6beta-hydroxy ... | 1975 | 808060 |
| vc11: an actinophage virulent to streptomyces cattleya and streptomyces olivaceus. | five soil samples were screened for the presence of a virulent actinophage. phage vc11 was found to be virulent on streptomyces olivaceus, s. cattleya, s. chartreusis, s. griseus (all important beta-lactam antibiotic producers), s. ambofaciens, s. parvulus, s. alboflavus, s. aureofaciens, and s. lividans tc10. although restriction-modification systems have been observed in s. olivaceus and s. cattleya, the phage eop on these hosts remained relatively constant, indicating that these systems do no ... | 1986 | 3013797 |
| metabolic products of microorganisms. 249. tetracenomycins b3 and d3, key intermediates of the elloramycin and tetracenomycin c biosynthesis. | tetracenomycins b3 and d3, besides tetracenomycin d (d1), were produced by a blocked mutant of the elloramycin producer streptomyces olivaceus tu 2353. the compounds were isolated as red powders, and their structures were elucidated by comparing their physicochemical data with those of the known tetracenomycins a2, b1, b2, d and e. tetracenomycin b3 (2), the main compound, and tetracenomycin d (3) were antibiotically inactive against gram-positive and gram-negative bacteria, whereas tetracenomyc ... | 1988 | 3170342 |
| elloramycins b, c, d, e and f: minor congeners of the elloramycin producer streptomyces olivaceus. | | 1986 | 3755429 |
| a new olivanic acid derivative produced by streptomyces olivaceus: isolation and structural studies. | | 1982 | 6983522 |
| [isolation of plasmid dna from streptomyces olivaceus v kx]. | | 1978 | 683024 |
| metabolic products of microorganisms. 225. elloramycin, a new anthracycline-like antibiotic from streptomyces olivaceus. isolation, characterization, structure and biological properties. | elloramycin (1), a new antibiotic produced by streptomyces olivaceus strain tü 2353, was detected by chemical screening. the dark yellow compound, molecular formula c32h36o15, is weakly active against a variety of gram-positive bacteria, especially streptomycetes and against stem cells of l-1210 leukemia. acidic hydrolysis of the antibiotic liberated elloramycinone (3) as aglycone and 2,3,4-tri-o-methyl-l-rhamnose, which was identified as methyl glycoside 5b. the structure of elloramycin was est ... | 1985 | 3840789 |
| [production of vitamin b12 by fermentation]. | in this work, the methods and technology of vitamin b12 production were studied on laboratory scale. the microorganisms used for experiments were streptomyces olivaceus ifo 3409, streptomyces olivaceus cbs 355.53 and streptomyces griseus cbs 161.45 which were brought from foreign countries. vitamin b12 activity that have been obtained from fermentation experiments of each microorganisms are determined by microbiological assays using lactobacillus leichmannii ifo 3073 (atcc 4797) which is a test ... | 1985 | 3938519 |
| [data in favor of bidirectional replication of actinomyces olivaceus v kx chromosome]. | | 1973 | 4779952 |
| [self-inhibition and antagonism in actinomyces olivaceus]. | | 1974 | 4465677 |
| [some data on the vitamin b-12 and methionine synthesis of cysteine- and methionine-deficient mutants of actinomyces olivaceus v kx]. | | 1973 | 4701198 |
| [actinomyces olivaceus v kx, a new subject for genetics of actinonycetaceae]. | | 1973 | 4573577 |
| [the effect of conditions of cultivation on lipid formation and their fatty acid composition in cobamide synthesizing actinomyces olivaceus]. | | 1974 | 4828741 |
| streptomyces olivaceus 142. ii. isolation of the antibiotic and its properties. | | 1969 | 5370182 |
| four further antibiotics related to olivanic acid produced by streptomyces olivaceus: fermentation, isolation, characterisation and biosynthetic studies. | four beta-lactam antibiotics with beta-lactamase inhibitory activity mm 22380, mm 22381, mm 22382 and mm 22383 containing the carbapenem nucleus have been isolated from a culture of streptomyces olivaceus atcc 31365. fermentation conditions for their production and methods for their isolation are described. evidence for a biosynthetic link between these compounds and the previously described olivanic acid derivatives mm 4550, mm 13902 and mm 17880 is presented. | 1979 | 317283 |
| [production of keto acids by actinomyces olivaceus cultures]. | | 1969 | 5396574 |
| [on the biosynthesis of vitamins of the b12 group by actinomyces olivaceus on synthetic medium]. | | 1965 | 5872108 |
| [on porphyrins biosynthesis during growth of actinomyces olivaceus, a producer of vitamin b-12]. | | 1966 | 6000115 |
| [cholesterol in streptomyces olivaceus]. | | 1967 | 6030366 |
| synthesis of vitamin b12 and b12-like compound by streptomyces olivaceus. | | 1956 | 13363414 |
| [mapping uvs1 and uvs2 mutations in streptomyces olivaceus vkx]. | | 1983 | 6336571 |
| [effect of hydrocarbons on the content and composition of lipids of actinomyces olivaceus]. | | 1973 | 4701620 |
| [mapping of the uvs3, uvs4, uvs5 and uvs6 mutations in streptomyces olivaceus v kx]. | | 1983 | 6400781 |
| [cytological examination of actinomyces olivaceus cells infected with actinophage]. | | 1963 | 13935752 |
| [on vitamin b-12 biosynthesis by actinomyces olivaceus in a synthetic medium in the presence of 5,6-dimethylbenzimidazole]. | | 1963 | 14074533 |
| [interspecies recombination in streptomyces griseus, streptomyces olivaceus and streptomyces coelicolor]. | | 1982 | 6803104 |
| [metabolism of amino acids during the formation of vitamin b12 by strain of actinomyces olivaceus]. | | 1963 | 14114537 |
| pathways of glucose dissimilation by streptomyces olivaceus. | | 1959 | 14420064 |
| trace elements and the synthesis of vitamin b12 by streptomyces olivaceus. | | 1960 | 14420065 |
| deacetylation of ps-5, a new beta-lactam compound, i. microbial deacetylation of ps-5. | ps-5 was deacetylated to ns-5 (deacetylated ps-5) by l-amino acid acylase from porcine kidney and d-amino acid acylase from streptomyces olivaceus but not by l-amino acid acylase from aspergillus sp. using ps-5, n-chloroacetyl-l-phenylalanine and n-chloroacetyl-d-valine as substrates, acylase producers were screened among facultative methanol-assimilating bacteria. most of the microbes tested were active and could be classified into two groups of l-acylase producers and l-& d-acylase producers. ... | 1980 | 6897941 |
| penicillin-binding proteins of streptomyces cacaoi, streptomyces olivaceus, and streptomyces clavuligerus. | penicillin-binding proteins of three streptomyces strains, s. cacaoi, s. olivaceus, and s. clavuligerus, were examined by gel electrophoresis and fluorography. in a beta-lactamase producer, s. cacaoi, at least five membrane-bound penicillin-binding proteins were detected, but in two beta-lactam producers, s. olivaceus and s. clavuligerus, fewer penicillin-binding proteins were detected. mecillinam and methicillin bound selectively to some penicillin-binding proteins in s. cacaoi, whereas they di ... | 1980 | 6965440 |
| comparative antibacterial properties in vitro of seven olivanic acid derivatives: mm 4550, mm 13902, mm 17880, mm 22380, mm 22381, mm 22382 and mm 22383. | streptomyces olivaceus atcc 31365 produces a family of novel beta-lactam antibiotics collectively referred to as the olivanic acids. seven such compounds, mm 4550, mm 13902, mm 17880, mm 22380, mm 22381, mm 22382 and mm 22383 have been identified which have the same carbapenem nucleus but with different side chains attached to the nucleus. the compounds with an (8s) hydroxyethyl substituent and cis-orientated beta-lactam protons, mm 22380 and mm 22382, and their sulphate esters, mm 17880 and ... | 1980 | 6968745 |
| [actinomyces olivaceus metabolite that stimulates zygote formation in phycomyces blakesleeanus]. | | 1973 | 4790728 |
| [ultrastructural characteristics of actinomyces olivaceus in the process of development of a culture as related to lipid synthesis]. | the cytomorphology of an actinomyces olivaceus culture was studied, in the course of its submerged cultivation in two media differing in phosphate content, in relation to lipid biosynthesis. the cells (including those grown under the conditions of phosphate deficiency in the medium) have well-developed membranous apparatus, particularly during the exponential growth phase and in the transition to the stationary phase whose time depends on the composition of the medium. no visible defects were fo ... | 1981 | 7321913 |
| diol lipids. xxvi. identification of a threo-butane-2,3-diol phospholipid from actinomyces olivaceus. | | 1974 | 4373051 |
| accumulation of the angucycline antibiotic rabelomycin after disruption of an oxygenase gene in the jadomycin b biosynthetic gene cluster of streptomyces venezuelae. | dna from a region downstream of and overlapping the polyketide synthase (pks) gene cluster for jadomycin b biosynthesis in streptomyces venezuelae was cloned and sequenced. analysis of the nucleotide sequence located one complete orf (orf6), an incomplete one representing the 3' region of orf4 in the pks cluster, and a second incomplete one (orf7). the deduced amino acid sequences for orfs 6 and 7 resemble those of oxygenases. since a plausible biosynthetic pathway for jadomycin b includes an an ... | 1996 | 8581159 |
| kanchanamycins, new polyol macrolide antibiotics produced by streptomyces olivaceus tü 4018. i. taxonomy, fermentation, isolation and biological activities. | the kanchanamycins, a group of novel 36-membered polyol macrolide antibiotics were detected in the culture filtrate and mycelium of streptomyces olivaceus tü 4018 by hplc-diode-array and hplc-electrospray-mass-spectrometry screening. the compounds show antibacterial and antifungal activities, and are especially effective against pseudomonas fluorescens. besides the kanchanamycin complex, strain tü 4018 produces the 42-membered macrolactones, oasomycin a and desertomycin a, as well as tryptophan- ... | 1996 | 8823507 |
| kanchanamycins, new polyol macrolide antibiotics produced by streptomyces olivaceus tii 4018. ii. structure elucidation. | kanchanamycins are a new group of polyol macrolide antibiotics isolated from streptomyces olivaceus tü 4018. they all share a common bicyclic carbon skeleton formed by a 36-membered lactone ring and a 6-membered hemiacetal ring. a feature unusual for that class of macrolides is the terminal urea moiety observed in kanchanamycin a. the structures of the kanchanamycins were determined by electrospray ms and modern 2d nmr techniques. due to substantial overlap of the signals intensive use of invers ... | 1996 | 8823508 |
| (e)-4-oxonon-2-enoic acid, an antibiotically active fatty acid produced by streptomyces olivaceus tü 4018. | | 1996 | 8823520 |
| [the actinophages of actinomyces olivaceus and lysogenicity among the cultures of this species]. | | 1958 | 13589712 |
| synthesis of (e)-4-oxonon-2-enoic acid, a natural antibiotic produced by streptomyces olivaceus | (e)-4-oxonon-2-enoic acid (1), a natural antibiotic produced by streptomyces olivaceus, has been conveniently prepared in three steps starting from furan. | 1998 | 9599276 |
| identification of streptomyces olivaceus tü 2353 genes involved in the production of the polyketide elloramycin. | the genes for the production of elloramycin (elm) from streptomyces olivaceus (so) tü2353 were cloned using a polyketide synthase gene probe from the tetracenomycin pathway. a cosmid clone (16f4) isolated from a gene library of so tü2353 conferred tetracenomycin c and elm resistance to s. lividans tk64 and complemented a mutation in so tü2353r. introduction of cosmid 16f4 into s. lividans tk64 resulted in the production of 8-demethyl-tetracenomycin c, an intermediate of elm biosynthesis. | 1995 | 8529875 |
| [role of plasmids in the interspecies recombination of streptomyces olivaceus vkx and streptomyces coelicolar a3(2)]. | | 1982 | 7144605 |
| [verification of the systematic postion of collection strains of actinomyces olivaceus]. | | 1971 | 5580113 |
| [electron microscopic study of the structure of hairs on the capsule of the spores of actinomyces olivaceus vkx-50]. | | 1968 | 5745588 |
| digitoxosyltetracenomycin c and glucosyltetracenomycin c, two novel elloramycin analogues obtained by exploring the sugar donor substrate specificity of glycosyltransferase elmgt. | our explorations of glycosyltransferase elmgt from streptomyces olivaceus tü 2353, which shows an interesting flexibility regarding its sugar donor substrate, were extended toward various previously unexplored sugar co-substrates. the studies revealed that elmgt, which normally transfers l-rhamnose to 8-demethyltetracenomycin c as a crucial biosynthetic step in elloramycin biosynthesis, is also able to process an activated non-deoxygenated sugar, ndp-d-glucose, as well as ndp-l-digitoxose, which ... | 2002 | 12444703 |
| studies on vitamin b12 production with streptomyces olivaceus. | | 1953 | 13041183 |
| [study of methionine-free mutants of actinomyces olivaceus v kx]. | | 1970 | 5479154 |
| tricarboxylic acid-cycle activity in streptomyces olivaceus. | | 1961 | 13765530 |
| [influence of various methylated substances supplementing soja flour on the biosynthesis of total cobalamines and vitamine b-12 by streptomyces olivaceus]. | | 1963 | 14095849 |
| biosynthesis of elloramycin in streptomyces olivaceus requires glycosylation by enzymes encoded outside the aglycon cluster. | elloramycin is an anthracycline-like antitumour drug produced by streptomyces olivaceus tü2353. cosmid cos16f4 has been previously shown to direct the biosynthesis of the elloramycin aglycon 8-demethyltetracenomycin c (8-dmtc), but not elloramycin. sequencing of the 24.2 kb insert in cos16f4 shows the presence of 17 genes involved in elloramycin biosynthesis (elm genes) together with another additional eight orfs probably not involved in elloramycin biosynthesis. the 17 genes would code for the ... | 2008 | 18310024 |