| [echovirus type 13 meningitis: admissions to a paediatric ward at a lisbon hospital]. | infections by echovirus 13 are rare. in our country, it had not been previously reported any infection of this sort until 2000, when eleven echovirus 13 meningitis were observed in the department of pediatrics of the hospital fernando fonseca. in england and spain outbreaks of echovirus 13 meningitis during 2000 was also reported. based on these facts the authors make an epidemiological analyses of their series. | 2004 | 15941555 |
| clinical spectrum in hospitalized children with echovirus type 13 infection. | the aim of this study was to investigate the clinical spectrum of echovirus type 13 (e13) infection in hospitalized children. | 2005 | 15771698 |
| analysis of the serotype and genotype correlation of vp1 and the 5' noncoding region in an epidemiological survey of the human enterovirus b species. | the sequence identity of the enterovirus vp1 gene has been shown to correlate with the serotype concept. enterovirus molecular typing methods are therefore often based on sequencing of the vp1 genomic region and monophyletic clustering of vp1 sequences of a homologous serotype. for epidemiological surveillance, 342 enterovirus samples obtained from patients with aseptic meningitis in belgium from 1999 to 2002 were first diagnosed as being enterovirus positive by amplification of the 5' noncoding ... | 2004 | 15004039 |
| [clinical analysis of aseptic meningitis caused by echovirus 13]. | we examined the clinical symptoms and laboratory findings of 21 children with aseptic meningitis caused by echovirus 13 during the summer of 2002. all patients (mean age: 8.3 years) complained of fever and headache. some had mild vomiting and some had severe vomiting of 4 times or more. in the early stage of the disease, the mean count of wbc was 8,283/microliter, mean level of crp was 0.8 mg/dl, and there were no abnormalities in levels of got, gpt, or ldh. the levels of protein and sugar, in c ... | 2003 | 14574843 |
| molecular evidence of persistent echovirus 13 meningoencephalitis in a patient with relapsed lymphoma after an outbreak of meningitis in 2000. | enteroviral meningoencephalitis was diagnosed in a patient with an immunodeficiency syndrome acquired after treatment with rituximab for a relapsed primary b-cell lymphoma. a second meningoencephalitic episode was diagnosed 6 months later and was successfully treated with a combination of immunoglobulins and pleconaril. the infection was persistent since the enterovirus genome was detected in five sequential specimens of cerebrospinal fluid collected over 9 months. an echovirus 13 isolate was is ... | 2003 | 14532190 |
| [epidemic outbreak of meningitis due to echovirus type 13 on the island of gran canaria (spain)]. | since the implementation of routine vaccination against mumps, enteroviruses have become the commonest cause of viral meningitis. in spain the most frequently isolated echoviruses are serotypes 30, 9, 6 and 4.objectives. determine the clinical-epidemiological characteristics of a meningitis outbreak due to echovirus type 13. | 2003 | 14525689 |
| molecular analysis of echovirus 13 isolates and aseptic meningitis, spain. | echovirus 13 (ev13), considered rare, was reported worldwide in 2000, mostly related to aseptic meningitis outbreaks. in spain, 135 ev13 isolates were identified. the genetic relationships between 64 representative strains from spain and other reported isolates from the united states, germany, italy, japan, and sweden were described by analyzing the partial sequence of the major capsid protein (vp1) gene. the strains from spain were clearly identified as ev13 (79.5% similarity with the ev13 refe ... | 2003 | 12967490 |
| an outbreak of echovirus 13 meningitis in central israel. | until recently, echovirus 13 has been a very rare cause of aseptic meningitis. we investigated an outbreak of echovirus 13 in central israel during the summer of 2000 using a prospective case control study and a retrospective study. echovirus 13 was isolated from 79 cerebrospinal fluid (csf) specimens from different medical centres in central israel. patients' ages ranged from 10 days to 41 years (95% < 15 years, m/f ratio 62/38). a total of 128 patients with clinical aseptic meningitis were adm ... | 2003 | 12729194 |
| three echovirus serotypes responsible for outbreak of aseptic meningitis in rhône-alpes region, france. | during the year 2000 in the rhône-alpes region of france, 559 cases of aseptic meningitis due to enterovirus infection were recorded (approximate incidence, 10 cases per 100,000 population compared with a mean of 0.3 cases during endemic years in this region; p<0.001). cerebrospinal fluid samples were collected from all 559 patients and processed for enterovirus rna detection using a reverse transcriptase polymerase chain reaction assay only. in addition to the cerebrospinal fluid samples, 40 st ... | 2003 | 12649719 |
| outbreak of aseptic meningitis associated with echovirus 13. | before 2001, echovirus 13 accounted for only 65 of approximately 45,000 reported enteroviral isolates in the united states. during spring 2001, several outbreaks of echovirus 13 meningitis occurred, primarily affecting children. we investigated a large outbreak in shelby county, tn, to determine the characteristics and clinical manifestations of echovirus 13 meningitis. | 2002 | 12442025 |
| [lymphocytic meningitis in spain: a possible epidemic situation in 2000]. | in order to clarify the unexpected increase in 2000 of lymphocyticmeningitis analyzed in the centro nacional de microbiología,instituto de salud carlos iii, madrid, here we present their microbiological features. | 2002 | 12042133 |
| echovirus type 13--united states, 2001. | echoviruses constitute one of the major groups of the genus enterovirus and are associated with illnesses including aseptic meningitis, nonspecific rashes, encephalitis, and myositis (1). echovirus 13 is an enterovirus that rarely has been detected in the united states, accounting for only 65 of approximately 45,000 enterovirus isolates reported to cdc during 1970-2000. no associated outbreaks have been reported in this country. as of june 2001, eight state public health laboratories and one pri ... | 2001 | 11570484 |
| enterovirus infections in england and wales: laboratory surveillance data: 1975 to 1994. | microbiology laboratories in england and wales reported 40,366 culture confirmed isolates of echovirus (24,628; 61%) and coxsackievirus (b 11,714; 29%, a 4024; 10%) infections to the phls communicable disease surveillance centre (cdsc) in the 20 years from 1975 to 1994. nearly half of the organisms were isolated from faeces, and 5741 were isolated from cerebrospinal fluid (75% of them echovirus, 13% coxsackie b, and 12% coxsackie a). isolation rates for all enteroviruses were highest among infan ... | 1999 | 10402747 |
| enteroviruses in spain over the decade 1998-2007: virological and epidemiological studies. | human enteroviruses (hev) are the commonest cause of viral meningitis as well as other pathologies, therefore hev characterization is important both in patient management and epidemiological investigation. | 2010 | 20007023 |
| prospective identification of enteroviruses involved in meningitis in 2006 through direct genotyping in cerebrospinal fluid. | enterovirus infections were investigated with special emphasis on performing rapid molecular identification of enterovirus serotypes responsible for aseptic meningitis directly in cerebrospinal fluid (csf). enterovirus genotyping was carried out directly with specimens tested for the diagnostic procedure, using two seminested pcr assays designed to amplify the complete and partial gene sequences encoding the vp1 and vp4/vp2 capsid proteins, respectively. the method was used for identifying the e ... | 2008 | 17977989 |
| epidemiologic aspects and laboratory features of enterovirus infections in western germany, 2000-2005. | from 2000 to 2005, a total of 1,096 enterovirus infections were diagnosed either by isolation of virus from cell culture or by rt-pcr (5'non-coding region (ncr)). typing of viruses (n = 674) was carried out by immunofluorescence with monoclonal antibodies, neutralization test or molecular methods. seasons with high enterovirus activity were characterized by high prevalence of echovirus 30 (62.2% in 2000, 25.5% in 2001) and echovirus 13 (34.5% in 2001). in contrast, in the 2003 season, which had ... | 2007 | 17516529 |
| molecular typing of enteroviruses associated with viral meningitis in cyprus, 2000-2002. | human enteroviruses are responsible for a wide spectrum of clinical diseases affecting many different organ systems. although infection is usually asymptomatic, infections of the central nervous system manifested as meningitis or encephalitis can pose a serious public health problem, especially during outbreaks. in this study, samples from 218 patients diagnosed with enteroviral meningitis between january 2000 and december 2002 were analysed in order to assess the epidemiology of human enterovir ... | 2006 | 16849723 |
| epidemiological study of non-polio enterovirus neurological infections in children in the region of monastir, tunisia. | the epidemiological, virological, and clinical syndromes of 86 children younger than 13 years suspected of having neurological diseases and admitted to fattouma bourguiba hospital of monastir from january 2002 to november 2003 were analyzed. the presence of enterovirus was studied in cerebrospinal fluid (csf) samples by reverse transcription-polymerase chain reaction (rt-pcr) and by isolation on cell culture. sixty-one (71%) specimens were positive by rt-pcr, whereas 45 (52.3%) were detected by ... | 2006 | 16290030 |
| an outbreak of viral meningitis associated with a public swimming pond. | from july to october 2001, 215 cases of aseptic meningitis occurred among the inhabitants of the german city of kassel and neighbouring counties. a matched case-control study identified bathing in a public, nature-like pond during the beginning of the outbreak as a risk factor for disease [matched odds ratio (mor) 44.8, 95% confidence interval (ci) 3.9-515.6]. among bathers, patients with meningitis spent more time in the water (mor 18.8, 95% ci 2.0-174.1) and swallowed water more frequently (mo ... | 2005 | 15816154 |
| isolation and molecular identification of echovirus 13 isolated from patients of aseptic meningitis in korea, 2002. | during 2002, several epidemics of aseptic meningitis were attributed to echovirus 13 in korea. the causative agents of these outbreaks were isolated and identified using rhabdosarcoma cells, hep-2 and buffalo green monkey kidney cells, and a neutralization test using monospecific antiserum. fifty-four echovirus 13 isolates were isolated from patients with aseptic meningitis in the provinces, seoul, kyonggi, gwangju, jeonju, busan, and ulsan. symptoms associated with aseptic meningitis infection ... | 2004 | 15170640 |
| assessment of an enterovirus sewage surveillance system by comparison of clinical isolates with sewage isolates from milwaukee, wisconsin, collected august 1994 to december 2002. | the quantity and serotypes of enteroviruses (evs) in the influent of a local sewage treatment plant were compared to local clinical ev cases to determine if testing of sewage is adequate for an ev surveillance system. the study was carried out from august 1994 to december 2002. monthly influent specimens were processed by organic flocculation, and dilutions of concentrate were inoculated onto a number of different cell types for virus isolation. evs were detected in 88 of 100 monthly influent sa ... | 2003 | 14660364 |
| pleconaril revisited: clinical course of chronic enteroviral meningoencephalitis after treatment correlates with in vitro susceptibility. | human enteroviruses (hevs) can cause severe infections, especially in patients with a deficient humoral immune response, such as x-linked agammaglobulinemia. in this patient group, chronic enteroviral meningitis (cema) is feared because of extensive morbidity and high fatality rate. treatment options consist of intravenous immunoglobulin (ivig), with various outcomes. pleconaril is an antiviral agent with in vitro activity against hevs that has been used in the treatment of hev infections. | 2011 | 22293148 |
| outbreak of echovirus 13 infection among lithuanian children. | the aim of this study was to investigate an outbreak of enterovirus infection in lithuania in 2001, as well as the clinical presentation and outcome of the disease. thirty children aged 1 month to 15 years were referred to hospital with suspected enterovirus infection during the period august-october 2001. echovirus 13 (ev-13) was isolated from eight (26.7%) cases. no other pathogens were detected. infection presented predominantly as viral meningitis, and rarely as a febrile illness with rash. ... | 2004 | 15522010 |
| molecular characterization of echovirus 13 uncovering high genetic diversity and identification of new genotypes in pakistan. | echovirus 13 (e-13) is reported worldwide and is mostly related to aseptic meningitis but it is also isolated from cases of acute flaccid paralysis (afp). unfortunately, all studies conducted on non polio enterovirus in pakistan only confirm e-13 isolation based on microneutralization assay but there is lack of molecular epidemiological data on this serotype. in this study, 113 stool samples were collected from afp patients during 2008-2010. an enterovirus primer mediated real-time reverse trans ... | 2017 | 28011278 |
| genetic variants of echovirus 13, northern india, 2010. | nonpolio acute flaccid paralysis is increasing in india. to determine viral causes, we conducted cell culture and molecular analysis identification of nonpolio human enteroviruses associated with acute flaccid paralysis during march-august 2010 in northern india. the predominant nonpolio enterovirus found was echovirus 13, a serotype rarely isolated in india. | 2013 | 23343581 |
| echovirus 13 aseptic meningitis, brazil. | | 2006 | 16977690 |
| [the genetic characterization of enteric cytopathic human orphanviruses type 13 isolated in shandong province]. | to analysis the genetic characteristics of echo 13 isolated from stool specimens of afp patient in shandong. | 2009 | 20084891 |
| enterovirus meningitis in brazil, 1998-2003. | acute viral infections of the central nervous system (cns) such as acute flaccid paralysis, meningitis, and encephalitis, are responsible for a high morbidity, particularly in children. non-polio enteroviruses (npev) are known to be responsible for over 80% of viral meningitis in which the etiologic agent is identified. in the present study, we show the frequency of enterovirus meningitis in brazil from december 1998 to december 2003. enterovirus were isolated from 162 (15.8%), of a total of 1,0 ... | 2006 | 16299728 |
| molecular typing and epidemiology of enteroviruses identified from an outbreak of aseptic meningitis in belgium during the summer of 2000. | non-polio enteroviruses are the most common cause of aseptic meningitis worldwide. from may to september 2000, a major outbreak of aseptic meningitis occurred in belgium. cerebrospinal fluid samples (csf) of 122 patients were found to contain enterovirus rna using diagnostic rt-pcr that targeted a 231-bp gene fragment in the 5' noncoding region. in addition, a molecular typing method was developed based on rt-nested pcr and sequencing directly from csf(a) 358-bp fragment in the aminoterminal par ... | 2003 | 12767006 |