| genetic and phenotypic analysis of borrelia miyamotoi sp. nov., isolated from the ixodid tick ixodes persulcatus, the vector for lyme disease in japan. | the ixodid tick ixodes persulcatus is the most important vector of lyme disease in japan. most spirochete isolates obtained from i. persulcatus ticks have been classified as borrelia burgdorferi sensu lato because of their genetic, biological, and immunological characteristics. however, we found that a small number of isolates obtained from i. persulcatus contained a smaller 38-kda endoflagellar protein and single 23s-5s rrna gene unit. representative isolate ht31t (t = type strain) had the same ... | 1995 | 7547303 |
| the flagellin gene of borrelia miyamotoi sp. nov. and its phylogenetic relationship among borrelia species. | we have cloned and sequenced the flagellin gene from borrelia miyamotoi strain ht31 and compared it with previously published flagellin sequences. sequence similarity analysis demonstrated that strain ht31 is phylogenetically distant from the three species of lyme disease borreliae is deeply branched into the relapsing fever borrelia cluster. the result was in full agreement with the classification of borrelia strains using 16s trna sequences. this finding indicates that a phylogenetic analysis ... | 1995 | 8586277 |
| homology of variable major protein genes between borrelia hermsii and borrelia miyamotoi. | antigenic variation has been studied in detail for the etiological agent of relapsing fever, borrelia hermsii. the variable major proteins (vmps) are found at its cell surface, enabling it to avoid the host's immune response. we have cloned and sequenced the vmp-gene (vmp)-like sequences from the borrelia miyamotoi strains ht31 and fr64b and the deduced amino acid sequences were compared with the published vmp proteins vmp3, vmp24, and vmp33 of b. hermsii. the sequences were aligned and revealed ... | 1996 | 8764474 |
| phylogenesis of relapsing fever borrelia spp. | the phylogenetic relationships of 20 relapsing fever (rf) borrelia spp. were estimated on the basis of the sequences of rrs genes. complete sequences were aligned and compared with previously published sequences, and the similarity values were found to be 97.7 to 99.9%. phylogenetic trees were constructed by using the three neighbor-joining, maximum-parsimony, and maximum-likelihood methods. the results of the comparative phylogenetic analysis divided the rf borrelia spp. into three major cluste ... | 1996 | 8863409 |
| phylogenetic analysis of borrelia species based on flagellin gene sequences and its application for molecular typing of lyme disease borreliae. | we determined almost complete flagellin gene sequences of various borrelia species and aligned them with previously published sequences. a neighbor-joining phylogenetic analysis showed that the genus borrelia was divided into the following three major clusters: new world relapsing fever borreliae (borrelia turicatae, borrelia parkeri, and borrelia hermsii), old world relapsing fever borreliae (borrelia crocidurae, borrelia duttonii, and borrelia hispanica), and lyme disease borreliae (borrelia b ... | 1996 | 8863416 |
| physical mapping of the borrelia miyamotoi ht31 chromosome in comparison with that of borrelia turicatae, an etiological agent of tick-borne relapsing fever. | we report the construction of physical maps of chromosomes for borrelia miyamotoi ht31 (a new species of borrelia) and borrelia turicatae (relapsing fever agent) by pulsed-field gel electrophoresis of dna fragments generated by digestion of chromosomal dna with rare-cutting restriction endonucleases and reciprocal hybridization. the size of the b. miyamotoi ht31 chromosome was calculated to be approximately 925 kilobase pairs, and the chromosome for b. turicatae was estimated to be 951 kilobase ... | 1996 | 8877131 |
| determination of novel borrelia genospecies in swedish ixodes ricinus ticks. | a total of 301 adult questing ixodes ricinus ticks were collected at 15 different locations along the south and east coasts of sweden to determine the borrelia genospecies diversity. thirty-two ticks (11%) were found to be positive by nested pcr with borrelia burgdorferi sensu lato-specific primers. species determination was based on partial sequencing of the 16s rrna gene and the flagellin gene. five different borrelia species were found. the nucleotide sequence of the borrelia dna found in two ... | 2002 | 12202571 |
| a relapsing fever group spirochete transmitted by ixodes scapularis ticks. | a species of borrelia spirochetes previously unknown from north america has been found to be transmitted by ixodes scapularis ticks. infected ticks are positive for borrelia spp. by dfa test but negative for borrelia burgdorferi by polymerase chain reaction (pcr) using species-specific primers for 16s rdna, outer surface protein a, outer surface protein c, and flagellin genes. a 1,347-bp portion of 16s rdna was amplified from a pool of infected nymphs, sequenced, and compared with the homologous ... | 2001 | 12653133 |
| horizontally acquired genes for purine salvage in borrelia spp. causing relapsing fever. | unlike borrelia burgdorferi, the relapsing fever agent borrelia hermsii and the related borrelia miyamotoi had pura and purb genes of the purine salvage pathway. these were located among the rrna genes. phylogenetic analysis indicated that these genes had a different evolutionary history than those of orthologs in other spirochetes. | 2005 | 16113341 |
| three multiplex assays for detection of borrelia burgdorferi sensu lato and borrelia miyamotoi sensu lato in field-collected ixodes nymphs in north america. | two hundred fifty new jersey field-collected ixodes scapularis say ticks and 17 colorado ixodes spinipalpis hadwen & nuttall ticks were tested using three separate multiplex real-time polymerase chain reaction (pcr) assays. one assay targets the rrs-rrla igs region of borrelia spp. to detect borrelia burgdorferi sensu lato (s.l.) and borrelia miyamotoi s.l. the second assay targets the ospa region of b. burgdorferi s.l. to detect b. burgdorferi sensu stricto (s.s.), borrelia bissettii, and borre ... | 2005 | 16465748 |
| detection of a borrelia miyamotoi sensu lato relapsing-fever group spirochete from ixodes pacificus in california. | we investigated whether host-seeking nymphs and adults of the western blacklegged tick, ixodes pacificus cooley & kohls, the primary vector of lyme disease spirochetes in far-western north america, are infected naturally with relapsing-fever group spirochetes in mendocino county, california. relapsing-fever group borreliae were detected in four (1.7%) of 234 nymphal and two (0.7%) of 282 adult host-seeking i. pacificus ticks by polymerase chain reaction and sequence analysis of the 16s rrna and ... | 2006 | 16506458 |
| [spatial and temporal variability of ixodes ricinus and ixodes persulcatus infection with the lyme disease agent in moscow region]. | analysis of long-term data on the infection rated of the taxonomic complex borrelia burgdorferi s. l. in ixodes persulcatus and i. ricinus from moscow region is carried out. more than 14 000 tick specimens were examined by dark-field microscopy and 704 specimens were investigated by pcr. two borrelia genospicies, b. afzelii (6.3%) and b. garinii (20%) proved the most prevalent. the genospecies could form a mixtinfection (11%). borrelia miyamotoi, b. valaisiana, and b. burgdorferi s. s. were also ... | 2008 | 19198169 |
| effects of tick control by acaricide self-treatment of white-tailed deer on host-seeking tick infection prevalence and entomologic risk for ixodes scapularis-borne pathogens. | we evaluated the effects of tick control by acaricide self-treatment of white-tailed deer on the infection prevalence and entomologic risk for three ixodes scapularis-borne bacteria in host-seeking ticks. ticks were collected from vegetation in areas treated with the "4-poster" device and from control areas over a 6-year period in five geographically diverse study locations in the northeastern united states and tested for infection with two known agents of human disease, borrelia burgdorferi and ... | 2009 | 19650738 |
| assessment of polymicrobial infections in ticks in new york state. | ixodes scapularis ticks are clinically important hematophagous vectors. a single tick bite can lead to a polymicrobial infection. we determined the prevalence of polymicrobial infection with borrelia burgdorferi, anaplasma phagocytophilum, babesia microti, borrelia miyamotoi, and powassan virus in 286 adult ticks from the two counties in new york state where lyme disease is endemic, utilizing a masstag multiplex polymerase chain reaction assay. seventy-one percent of the ticks harbored at least ... | 2010 | 19725770 |
| niche partitioning of borrelia burgdorferi and borrelia miyamotoi in the same tick vector and mammalian reservoir species. | the lyme borreliosis agent borrelia burgdorferi and the relapsing fever group species borrelia miyamotoi co-occur in the united states. we used species-specific, quantitative polymerase chain reaction to study both species in the blood and skin of peromyscus leucopus mice and host-seeking ixodes scapularis nymphs at a connecticut site. bacteremias with b. burgdorferi or b. miyamotoi were most prevalent during periods of greatest activity for nymphs or larvae, respectively. whereas b. burgdorferi ... | 2009 | 19996447 |
| a comparative analysis of molecular markers for the detection and identification of borrelia spirochaetes in ixodes ricinus. | borrelia burgdorferi sensu lato, carried by ixodes ticks, is one of the most significant human pathogens, causing lyme disease. as there is no standardized pcr method for detection and identification of spirochaete dna, we carried out a comparative analysis using a set of complementary primers for three regions in the genomic dna of these bacteria (genes fla and rrs and the non-coding rrs-rrla region). dna extracted from 579 ixodes ricinus ticks was subjected to nested pcr. dna of the examined s ... | 2010 | 20007765 |
| [detection of borrelia miyamotoi in ticks ixodes persulcatus from russia]. | unfed adult ixodes persulcatus ticks from five regions of russia were examined to analyze the distribution and diversity of borrelia miyamotoi. dna of b. miyamotoi was found in 1.8% of ticks from leningrad oblast, 2.9% from sverdlovsk, 4.5% from novosibirsk, 2.3% from irkutsk oblast, and 2.5% from khabarovsk krai. the molecular typing of the b. miyamotoi dna was based on the partial sequencing of the 16s rrna, p66, and glpq genes. the only genetic variant of b. miyamotoi was detected in all samp ... | 2010 | 20795483 |
| elimination of lyme disease spirochetes from ticks feeding on domestic ruminants. | to determine whether and which spirochetes are cleared from ixodes ricinus ticks during feeding on ruminants, ticks were removed from goats and cattle grazing on tick-infested pastures. although about a quarter of ticks questing on the pasture were infected by spirochetes, no molted ticks that had previously engorged to repletion on ruminants harbored lyme disease spirochetes. borrelia miyamotoi spirochetes, however, appear not to be eliminated. thus, the more subadult ticks are diverted from re ... | 2010 | 20870789 |
| high-prevalence borrelia miyamotoi [scapin wild turkeys (meleagris gallopavo) in tennessee. | during spring and fall 2009, 60 wild turkeys (meleagris gallopavo) harvested by tennessee hunters were surveyed for borrelia spp. by sampling their blood, tissue, and attached ticks. in both seasons, 70% of turkeys were infested with juvenile amblyomma americanum; one spring turkey hosted an adult female ixodes brunneus. polymerase chain reaction assays followed by dna sequencing indicated that 58% of the turkeys were positive for the spirochete borrelia miyamotoi, with tissue testing positive m ... | 2010 | 21175079 |
| [relapsing borrelioses fevers: forgotten and new ones]. | relapsing fever borrelioses are widely spread in the endemic regions of eurasia, africa, and america as before and account for significant morbidity and mortality; however, these infections have been recently underestimated. the pathogens of the fevers are the borrelia species transmitted by ticks of the ornithodoros genus; they genetically differ from the pathogens of lyme borreliosis--borrelia burgdorferi sensu lato transmitted by ixodes ticks. the species borrelia miyamotoi belongs to the gen ... | 2010 | 21381356 |
| investigation of genotypes of borrelia burgdorferi in ixodes scapularis ticks collected during surveillance in canada. | the genetic diversity of borrelia burgdorferi sensu stricto, the agent of lyme disease in north america, has consequences for the performance of serological diagnostic tests and disease severity. to investigate b. burgdorferi diversity in canada, where lyme disease is emerging, bacterial dna in 309 infected adult ixodes scapularis ticks collected in surveillance was characterized by multilocus sequence typing (mlst) and analysis of outer surface protein c gene (ospc) alleles. six ticks carried b ... | 2011 | 21421790 |
| [genetic features of borrelia miyamotoi transmitted by ixodes persulcatus]. | the definition and molecular typing of borrelia miyamotoi transmitted by the ixodes persuccatus ticks was based on the partial sequencing of the 16s rrna, p66, and glpq genes. all the b. miyamotoi analyzed sequences of the 16s rrna, glpq, and p66 gene fragments from i. persulcatus were identical and had 99.9-100% similarity to corresponding genes of the b. miyamotoi strain fr64b isolated in japan. the analyzed amino acid sequences revealed that the 66 protein b. miyamotoi in the site correspondi ... | 2011 | 21786631 |
| flab gene as a molecular marker for distinct identification of borrelia species in environmental samples by the pcr-restriction fragment length polymorphism method. | a new protocol employing nested pcr-restriction fragment length polymorphism (rflp) based on the flab gene and two restriction enzymes was worked out. this protocol allows the identification of all borrelia species transmitted by ixodes ricinus in europe, including borrelia miyamotoi and 3 genetic variants of b. garinii. a dendrogram of flab sequence similarity was in accordance with rflp variants. | 2011 | 21841027 |
| Absence of Lyme Disease Spirochetes in Larval Ixodes ricinus Ticks. | Abstract To determine which kind of spirochete infects larval Ixodes ricinus, we examined questing larvae and larvae derived from engorged females for the presence of particular spirochetal DNA that permitted species differentiation. Borrelia miyamotoi was the sole spirochete detected in larval ticks sampled while questing on vegetation. Questing nymphal and adult ticks were infected mainly by Borrelia afzelii, whereas larval ticks resulting from engorged females of the same population were so ... | 2011 | 21923267 |
| humans infected with relapsing fever spirochete borrelia miyamotoi, russia. | borrelia miyamotoi is distantly related to b. burgdorferi and transmitted by the same hard-body tick species. we report 46 cases of b. miyamotoi infection in humans and compare the frequency and clinical manifestations of this infection with those caused by b. garinii and b. burgdorferi infection. all 46 patients lived in russia and had influenza-like illness with fever as high as 39.5°c; relapsing febrile illness occurred in 5 (11%) and erythema migrans in 4 (9%). in russia, the rate of b. miya ... | 2011 | 22000350 |
| detection and genetic characterization of relapsing fever spirochete borrelia miyamotoi in estonian ticks. | during the years 2008-2010 i. ricinus and i. persulcatus ticks were collected from 64 sites in mainland estonia and on the island saaremaa. presence of b. miyamotoi was found in 0.9% (23/2622) of ticks. the prevalence in i. persulcatus and i. ricinus ticks differed significantly, 2.7% (15/561) and 0.4% (8/2061), respectively. the highest prevalence rates were in found south-eastern estonia in an area of i. persulcatus and i. ricinus sympatry and varied from 1.4% (1/73) to 2.8% (5/178). co-infect ... | 2012 | 23251652 |
| quantitative pcr for detection of babesia microti in ixodes scapularis ticks and in human blood. | babesia microti, the primary cause of human babesiosis in the united states, is transmitted by ixodes scapularis ticks; transmission may also occur through blood transfusion and transplacentally. most infected people experience a viral-like illness that resolves without complication, but those who are immunocompromised may develop a serious and prolonged illness that is sometimes fatal. the geographic expansion and increasing incidence of human babesiosis in the northeastern and midwestern unite ... | 2013 | 24107203 |
| ixodes ricinus and its transmitted pathogens in urban and peri-urban areas in europe: new hazards and relevance for public health. | tick-borne diseases represent major public and animal health issues worldwide. ixodes ricinus, primarily associated with deciduous and mixed forests, is the principal vector of causative agents of viral, bacterial, and protozoan zoonotic diseases in europe. recently, abundant tick populations have been observed in european urban green areas, which are of public health relevance due to the exposure of humans and domesticated animals to potentially infected ticks. in urban habitats, small and medi ... | 2014 | 25520947 |
| the relapsing fever spirochete borrelia miyamotoi is cultivable in a modified kelly-pettenkofer medium, and is resistant to human complement. | borrelia miyamotoi is a relapsing fever spirochete found in ixodes ticks in north america, europe, and asia, and has recently been found to be invasive in humans. cultivation of this spirochete has not yet been described, but is important for patient diagnostics and scientific purposes. host specificity of borrelia species is dependent on resistance to host complement (serum resistance), and since b. miyamotoi has been identified as a human pathogen we were interested whether b. miyamotoi is res ... | 2014 | 25189195 |
| detection, identification and genotyping of borrellia spp. in rodents in slovenia by pcr and culture. | borrelia burgdorferi sensu lato, the agent of lyme borreliosis, is mainly maintained in natural foci through the transmission cycles of competent tick vectors (ixodes sp.) and a vertebrate reservoir. specific rodents have been identified as the principal reservoir of borrelia burgdorferi sensu lato in europe. borrelia miyamotoi is the only relapsing fever spirochete transmitted by the same tick. the aim of the present study was to perform an epidemiological survey to determine the presence of b. ... | 2015 | 26253121 |
| eco-epidemiology of borrelia miyamotoi and lyme borreliosis spirochetes in a popular hunting and recreational forest area in hungary. | borrelia miyamotoi, the newly discovered human pathogenic relapsing fever spirochete, and borrelia burgdorferi sensu lato are maintained in natural rodent populations. the aim of this study was to investigate the natural cycle of b. miyamotoi and b. burgdorferi s.l. in a forest habitat with intensive hunting, forestry work and recreational activity in southern hungary. | 2015 | 26048373 |
| borrelia miyamotoi infection in nature and in humans. | borrelia miyamotoi is a relapsing fever borrelia group spirochete that is transmitted by the same hard-bodied (ixodid) tick species that transmit the agents of lyme disease. it was discovered in 1994 in ixodes persulcatus ticks in japan. b. miyamotoi species phylogenetically cluster with the relapsing fever group spirochetes, which usually are transmitted by soft-bodied (argasid) ticks or lice. b. miyamotoi infects at least six ixodes tick species in north america and eurasia that transmit lyme ... | 2015 | 25700888 |
| morgellons disease: a filamentous borrelial dermatitis. | morgellons disease (md) is a dermopathy characterized by multicolored filaments that lie under, are embedded in, or project from skin. although md was initially considered to be a delusional disorder, recent studies have demonstrated that the dermopathy is associated with tickborne infection, that the filaments are composed of keratin and collagen, and that they result from proliferation of keratinocytes and fibroblasts in epithelial tissue. culture, histopathological and molecular evidence of s ... | 2016 | 27789971 |
| molecular detection of tick-borne pathogens in humans with tick bites and erythema migrans, in the netherlands. | tick-borne diseases are the most prevalent vector-borne diseases in europe. knowledge on the incidence and clinical presentation of other tick-borne diseases than lyme borreliosis and tick-borne encephalitis is minimal, despite the high human exposure to these pathogens through tick bites. using molecular detection techniques, the frequency of tick-borne infections after exposure through tick bites was estimated. | 2016 | 27706159 |
| borrelia miyamotoi infection in patients from upper midwestern united states, 2014-2015. | we confirmed borrelia miyamotoi infection in 7 patients who had contracted an illness while near la crosse, wisconsin, usa, an area where ixodes scapularis ticks are endemic. b. miyamatoi infection should now be considered among differential diagnoses for patients from the midwestern united states who have signs and symptoms suggestive of tickborne illness. | 2016 | 27434048 |
| environmental factors influencing tick densities over seven years in a french suburban forest. | worldwide changes in socio-economic and environmental factors and the global climate are recognised causes of variation in tick distribution and density. thus it is of great importance that new studies address the changing risk of infection for exposed populations. in europe, ixodes ricinus ticks are the most common vectors of several pathogens impacting veterinary and public health that have colonised suburban habitats. | 2016 | 27234215 |
| human pathogens associated with the blacklegged tick ixodes scapularis: a systematic review. | the blacklegged tick ixodes scapularis transmits borrelia burgdorferi (sensu stricto) in eastern north america; however, the agent of lyme disease is not the sole pathogen harbored by the blacklegged tick. the blacklegged tick is expanding its range into areas of southern canada such as ontario, an area where exposure to blacklegged tick bites and tick-borne pathogens is increasing. we performed a systematic review to evaluate the public health risks posed by expanding blacklegged tick populatio ... | 2016 | 27151067 |
| tick-borne bacterial pathogens in southwestern finland. | ixodes ricinus and ixodes persulcatus are the main vectors of lyme borreliosis spirochetes and several other zoonotic bacteria in northern europe and russia. however, few studies screening bacterial pathogens in finnish ticks have been conducted. therefore, reports on the occurrence and prevalence of several bacterial pathogens detected from ticks elsewhere in europe and russia are altogether missing from finland. the main aim of the current study was to produce novel data on the occurrence and ... | 2016 | 27004834 |
| larvae of ixodes ricinus transmit borrelia afzelii and b. miyamotoi to vertebrate hosts. | lyme borreliosis is the most common tick-borne human disease and is caused by borrelia burgdorferi sensu lato (s.l.). borrelia miyamotoi, a relapsing fever spirochaete, is transmitted transovarially, whereas this has not been shown for b. burgdorferi (s.l). therefore, b. burgdorferi (s.l) is considered to cycle from nymphs to larvae through vertebrates. larvae of ixodes ricinus are occasionally b. burgdorferi (s.l) infected, but their vector competence has never been studied. | 2016 | 26896940 |
| high prevalence of borrelia miyamotoi among adult blacklegged ticks from white-tailed deer. | we compared the prevalence of borrelia miyamotoi infection in questing and deer-associated adult ixodes scapularis ticks in wisconsin, usa. prevalence among deer-associated ticks (4.5% overall, 7.1% in females) was significantly higher than among questing ticks (1.0% overall, 0.6% in females). deer may be a sylvatic reservoir for this newly recognized zoonotic pathogen. | 2016 | 26811985 |
| multiple and diverse vsp and vlp sequences in borrelia miyamotoi, a hard tick-borne zoonotic pathogen. | based on chromosome sequences, the human pathogen borrelia miyamotoi phylogenetically clusters with species that cause relapsing fever. but atypically for relapsing fever agents, b. miyamotoi is transmitted not by soft ticks but by hard ticks, which also are vectors of lyme disease borrelia species. to further assess the relationships of b. miyamotoi to species that cause relapsing fever, i investigated extrachromosomal sequences of a north american strain with specific attention on plasmid-born ... | 2016 | 26785134 |
| tick surveillance for relapsing fever spirochete borrelia miyamotoi in hokkaido, japan. | during 2012-2013, a total of 4325 host-seeking adult ticks belonging to the genus ixodes were collected from various localities of hokkaido, the northernmost island of japan. tick lysates were subjected to real-time pcr assay to detect borrelial infection. the assay was designed for specific detection of the relapsing fever spirochete borrelia miyamotoi and for unspecific detection of lyme disease-related spirochetes. overall prevalence of b. miyamotoi was 2% (71/3532) in ixodes persulcatus, 4.3 ... | 2014 | 25111141 |
| human exposure to tickborne relapsing fever spirochete borrelia miyamotoi, the netherlands. | | 0 | 24963562 |
| borrelia miyamotoi disease: neither lyme disease nor relapsing fever. | borrelia miyamotoi disease (bmd) is a newly recognized borreliosis globally transmitted by ticks of the ixodes persulcatus species complex. once considered to be a tick symbiont with no public health implications, b miyamotoi is increasingly recognized as the agent of a nonspecific febrile illness often misdiagnosed as acute lyme disease without rash, or as ehrlichiosis. the frequency of its diagnosis in the northeastern united states is similar to that of human granulocytic ehrlichiosis. a diag ... | 2015 | 26593262 |
| human infections with borrelia miyamotoi, japan. | we confirmed infection of 2 patients with borrelia miyamotoi in japan by retrospective surveillance of lyme disease patients and detection of b. miyamotoi dna in serum samples. one patient also showed seroconversion for antibody against recombinant glycerophosphodiester phosphodiesterase of b. miyamotoi. indigenous relapsing fever should be considered a health concern in japan. | 0 | 25061761 |
| phylogeny of a relapsing fever borrelia species transmitted by the hard tick ixodes scapularis. | the discovery of borrelia species that were related to the agents of relapsing fever but were transmitted by hard ticks rather than soft ticks challenged previous taxonomies based largely on microbe-host specificities and geographic considerations. one of these newly-identified organisms is the borrelia miyamotoi sensu lato strain lb-2001 from north america and transmitted by ixodes scapularis. this or related strains have been identified as the cause of human disease, but comparatively little i ... | 2014 | 24813576 |
| associations of passerine birds, rabbits, and ticks with borrelia miyamotoi and borrelia andersonii in michigan, u.s.a. | wild birds contribute to maintenance and dissemination of vectors and microbes, including those that impact human, domestic animal, and wildlife health. here we elucidate roles of wild passerine birds, eastern cottontail rabbits (sylvilagus floridanus), and ixodes dentatus ticks in enzootic cycles of two spirochetes, borrelia miyamotoi and b. andersonii in a region of michigan where the zoonotic pathogen b. burgdorferi co-circulates. | 2012 | 23057837 |
| melting pot of tick-borne zoonoses: the european hedgehog contributes to the maintenance of various tick-borne diseases in natural cycles urban and suburban areas. | european hedgehogs (erinaceus europaeus) are urban dwellers and host both ixodes ricinus and ixodes hexagonus. these ticks transmit several zoonotic pathogens like borrelia burgdorferi (sensu lato), anaplasma phagocytophilum, rickettsia helvetica, borrelia miyamotoi and "candidatus neoehrlichia mikurensis". it is unclear to what extent hedgehogs in (sub) urban areas contribute to the presence of infected ticks in these areas, which subsequently pose a risk for acquiring a tick-borne disease. the ... | 2017 | 28270232 |
| detection of borrelia miyamotoi and other tick-borne pathogens in human clinical specimens and ixodes scapularis ticks in new york state, 2012-2015. | borrelia miyamotoi (bm) is a recently emerging bacterial agent transmitted by several species of ixodid ticks. diagnosis of bm infection can be challenging, as the organism is not easily cultivable. we have developed and validated a multiplex real-time pcr to simultaneously identify bm infection and the agents causing human granulocytic anaplasmosis and human monocytic ehrlichiosis, anaplasma phagocytophilum and ehrlichia chaffeensis, respectively. the assay is 100% specific; highly sensitive, d ... | 2017 | 28131594 |
| prevalence and diversity of tick-borne pathogens in nymphal ixodes scapularis (acari: ixodidae) in eastern national parks. | tick-borne pathogens transmitted by ixodes scapularis say (acari: ixodidae), also known as the deer tick or blacklegged tick, are increasing in incidence and geographic distribution in the united states. we examined the risk of tick-borne disease exposure in 9 national parks across six northeastern and mid-atlantic states and the district of columbia in 2014 and 2015. to assess the recreational risk to park visitors, we sampled for ticks along frequently used trails and calculated the density of ... | 2016 | 28028138 |
| [did you know this about the diseases spread by ticks?]. | the number of ticks, members of the acarids, is increasing in the finnish nature, and the risk of tick-borne infections has therefore increased as well. the incidence of lyme borreliosis and tick-borne encephalitis has also increased over the past few years. possible recently discovered tick-borne infectious organisms include borrelia miyamotoi and anaplasma phagocytophilum bacteria and the babesia protozoon. although infections caused by these microorganism are presumed to be rare in finland, t ... | 2016 | 27522835 |
| distribution of ticks and the risk of lyme disease and other tick-borne pathogens of public health significance in ontario, canada. | over the past two decades, the northward spread of ixodes scapularis across ontario, canada, has accelerated and the risk of lyme disease has increased. active surveillance is a recognized and effective method for detecting reproducing populations of i. scapularis. in this study, we conducted field sampling consistent with an active surveillance approach from may to october 2014 at 104 sites in central, eastern, and southern ontario to determine the current distribution of i. scapularis and othe ... | 2016 | 26870937 |
| lyme disease coinfections in the united states. | lyme disease in north america is caused by infection with the spirochetal bacterium borrelia burgdorferi and transmitted by ixodes scapularis and ixodes pacificus ticks. these ticks also have the potential to transmit a rapidly expanding list of other pathogenic bacteria, viruses, and parasites, including anaplasma phagocytophilum, babesia microti, deer tick (powassan) virus, borrelia miyamotoi, and the ehrlichia muris-like organism. coinfections with b burgdorferi and these other agents are oft ... | 2015 | 26593260 |
| relatively low prevalence of babesia microti and anaplasma phagocytophilum in ixodes scapularis ticks collected in the lehigh valley region of eastern pennsylvania. | several human pathogens are transmitted by the blacklegged tick, ixodes scapularis. these include the spirochetes that cause lyme disease (borrelia burgdorferi) which is endemic to the lehigh valley region of eastern pennsylvania. emerging and currently rare tick-borne diseases have been of increasing concern in this region, including tick-borne relapsing fever (caused by borrelia miyamotoi), human granulocytic anaplasmosis (caused by anaplasma phagocytophilum), and human babesiosis (caused by b ... | 2015 | 26318263 |
| tick-borne bacteria in ixodes ricinus collected in southern norway evaluated by a commercial kit and established real-time pcr protocols. | ticks are important vectors of human pathogens. the knowledge of disease causing agents harboured by ticks in norway is limited. the focus of this study was (a) to detect the bacteria of medical importance in ticks collected from the vegetation at locations in the southern part of the country and (b) to evaluate a novel commercially available multiplex pcr based method by comparing results with conventional established real-time pcr protocols. borrelia burgdorferi sensu lato was confirmed to be ... | 2015 | 25985721 |
| borrelia miyamotoi in host-seeking ixodes ricinus ticks in england. | this paper reports the first detection of borrelia miyamotoi in uk ixodes ricinus ticks. it also reports on the presence and infection rates of i. ricinus for a number of other tick-borne pathogens of public health importance. ticks from seven regions in southern england were screened for b. miyamotoi, borrelia burgdorferi sensu lato (s.l.), anaplasma phagocytophilum and neoehrlichia mikurensis using qpcr. a total of 954 i. ricinus ticks were tested, 40 were positive for b. burgdorferi s.l., 22 ... | 2015 | 25017971 |
| increased diversity of zoonotic pathogens and borrelia burgdorferi strains in established versus incipient ixodes scapularis populations across the midwestern united states. | the center of origin theory predicts that genetic diversity will be greatest near a specie's geographic origin because of the length of time for evolution. by corollary, diversity will decrease with distance from the origin; furthermore, invasion and colonization are frequently associated with founder effects that reduce genetic variation in incipient populations. the blacklegged tick, ixodes scapularis, harbors a suite of zoonotic pathogens, and the geographic range of the tick is expanding in ... | 2014 | 24953506 |
| are apodemus spp. mice and myodes glareolus reservoirs for borrelia miyamotoi, candidatus neoehrlichia mikurensis, rickettsia helvetica, r. monacensis and anaplasma phagocytophilum? | in europe, in addition to borrelia burgdorferi sensu lato and tick-borne encephalitis (tbe) virus, other zoonotic pathogens, like b. miyamotoi, a species related to the relapsing fever spirochaetes, candidatus neoehrlichia mikurensis (n. mikurensis), rickettsia helvetica, rickettsia monacensis, and anaplasma phagocytophilum have been reported in the ixodid tick ixodes ricinus. no study was conducted to identify reservoir hosts for these pathogens. here, we investigated the role played by wild ro ... | 2014 | 24582511 |
| borrelia miyamotoi infection presenting as human granulocytic anaplasmosis: a case report. | the diverse tickborne infections of the northeastern united states can present as undifferentiated flu-like illnesses. in areas endemic for lyme and other tickborne diseases, patients presenting with acute febrile illness with myalgia, headache, neutropenia, thrombocytopenia, and elevated hepatic aminotransferase levels are presumptively diagnosed as having human granulocytic anaplasmosis (hga). | 2013 | 23817701 |
| molecular survey of zoonotic agents in rodents and other small mammals in croatia. | croatia is a focus for many rodent-borne zoonosis. here, we report a survey of 242 rodents and small mammals, including 43 myodes glareolus, 131 apodemus flavicollis, 53 apodemus agrarius, three apodemus sylvaticus, six sorex araneus, four microtus arvalis, one microtus agrestis, and one muscardinus avellanarius, collected at eight sites in croatia over an 8-year period. multiplex masstag polymerase chain reaction (pcr) was used for detection of borrelia, rickettsia, bartonella, babesia, ehrlich ... | 2016 | 26711522 |
| [dna detection of pathogens transmitted by ixodid ticks in blood of small mammals inhabiting the forest biotopes in middle irtysh area (omsk region, west siberia)]. | microtine rodents were captured in two disconnected sampling sites in omsk region where ixodes pesulrcatus and ixodes trianguliceps are sympatric. in blood samples of rodents the dna was revealed belonging to several ixodid-transmitted pathogens: borrelia burgdorferi sensu lato (prevalence 20.0 and 6.0%, here and further values are given for the first and second site, respectively), borrelia miyamotoi (8.3 and 2.0%), anlaplasnma phagocytophilum (33.3 and 48.0%), ehrlichia muris (30.0 and 2.0%) a ... | 2014 | 25507835 |
| [dna detection of pathogens transmitted by ixodid ticks in blood of small mammals inhabiting the forest biotopes in middle irtysh area (omsk region, west siberia)]. | microtine rodents were captured in two disconnected sampling sites in omsk region where ixodes pesulrcatus and ixodes trianguliceps are sympatric. in blood samples of rodents the dna was revealed belonging to several ixodid-transmitted pathogens: borrelia burgdorferi sensu lato (prevalence 20.0 and 6.0%, here and further values are given for the first and second site, respectively), borrelia miyamotoi (8.3 and 2.0%), anlaplasnma phagocytophilum (33.3 and 48.0%), ehrlichia muris (30.0 and 2.0%) a ... | 2014 | 25434237 |
| immune evasion of borrelia miyamotoi: cbia, a novel outer surface protein exhibiting complement binding and inactivating properties. | borrelia (b.) miyamotoi, an emerging tick-borne relapsing fever spirochete, resists complement-mediated killing. to decipher the molecular principles of immune evasion, we sought to identify determinants contributing to complement resistance. employing bioinformatics, we identified a gene encoding for a putative factor h-binding protein, termed cbia (complement binding and inhibitory protein a). functional analyses revealed that cbia interacted with complement regulator factor h (fh), c3, c3b, c ... | 2017 | 28331202 |
| evaluation of a serological test for the diagnosis of borrelia miyamotoi disease in europe. | borrelia miyamotoi causes systemic febrile illness and is transmitted by the same tick species that transmits borrelia burgdorferi sensu lato and tick-borne encephalitis virus. we describe a serological test using a fragment of glycerophosphodiester phosphodiesterase (glpq) as an antigen, and determined its performance in well-defined patient categories. | 2017 | 28259789 |
| the first case of imported borrelia miyamotoi disease concurrent with lyme disease. | borrelia miyamotoi disease (bmd) is an emerging infectious disease caused by b. miyamotoi. although bmd has been reported in the united states, europe, and japan, no case of imported bmd has been described in the world. here, we report a 63-year-old american man living in japan who presented with malaise, headache, myalgia, and arthralgia. we suspected lyme disease because of his travel history to minnesota and presence of erythema migrans. serologic analysis supported our diagnosis, and doxycyc ... | 2017 | 28162921 |
| host immune evasion by lyme and relapsing fever borreliae: findings to lead future studies for borrelia miyamotoi. | the emerging pathogen, borrelia miyamotoi, is a relapsing fever spirochete vectored by the same species of ixodes ticks that carry the causative agents of lyme disease in the us, europe, and asia. symptoms caused by infection with b. miyamotoi are similar to a relapsing fever infection. however, b. miyamotoi has adapted to different vectors and reservoirs, which could result in unique physiology, including immune evasion mechanisms. lyme borrelia utilize a combination of ixodes-produced inhibito ... | 2017 | 28154563 |
| toward a complete north american borrelia miyamotoi genome. | borrelia miyamotoi, of the relapsing-fever spirochete group, is an emerging tick-borne pathogen causing human illness in the northern hemisphere. here, we present the chromosome, eight extrachromosomal linear plasmids, and a draft sequence for five circular and one linear plasmid of a borrelia miyamotoi strain isolated from an ixodes sp. tick from connecticut, usa. | 2017 | 28153903 |
| development and optimization of an in vitro cultivation protocol allows for isolation of borrelia miyamotoi from patients with hard tick-borne relapsing fever. | borrelia miyamotoi has been shown to infect humans in eurasia and north america causing hard tick-borne relapsing fever (htbrf). in vitro cultivation of b. miyamotoi was described recently; but clinical isolation of relapsing fever borrelia is cumbersome. our aim was to develop a straightforward protocol enabling b. miyamotoi isolation directly from the blood of patients. | 2017 | 28110053 |
| borrelia miyamotoi in vectors and hosts in the netherlands. | ixodes ticks transmit borrelia burgdorferi sensu lato (s.l.), the causative agent of lyme borreliosis (lb). these tick species also transmit borrelia miyamotoi, which was recently found to cause infections in humans. we were interested in the prevalence of b. miyamotoi infection in ticks and natural hosts in the netherlands, and to what extent ticks are co-infected with b. burgdorferi. in addition, erythema migrans has been sporadically described in b. miyamotoi-infected patients, but these skin ... | 2017 | 28065617 |
| diagnosing borreliosis. | borrelia species fall into two groups, the borrelia burgdorferi sensu lato (bbsl) complex, the cause of lyme borreliosis (also known as lyme disease), and the relapsing fever group. both groups exhibit inter- and intraspecies diversity and thus have variations in both clinical presentation and diagnostic approaches. a further layer of complexity is derived from the fact that ticks may carry multiple infectious agents and are able to transmit them to the host during blood feeding, with potential ... | 2017 | 28055580 |
| [follow-up of patients with ixodes tick-borne borrelioses caused by borrelia miyamotoi or borrelia burgdorferi sensu lato]. | ixodes tick-borne borrelioses (itbb) are caused by two different spirochetes: borrelia from the group of borrelia burgdorferi sensu lato, the agents of the classic lyme borreliosis (lb), and borrelia miyamotoi that belongs to the group of borrelia causing tick-borne relapsing fevers. itbb caused by b. miyamotoi (bm-itbb) is a previously unknown infectious disease discovered in russia. it is known that the lb sequelae may reduce the long-term life guality of convalescents. | 2016 | 28005031 |
| borrelia miyamotoi and co-infection with borrelia afzelii in ixodes ricinus ticks and rodents from slovakia. | borrelia miyamotoi causes relapsing fever in humans. the occurrence of this spirochete has been reported in ixodes ricinus and wildlife, but there are still gaps in the knowledge of its eco-epidemiology and public health impact. in the current study, questing i. ricinus (nymphs and adults) and skin biopsies from rodents captured in slovakia were screened for the presence of b. miyamotoi and borrelia burgdorferi s.l. dna. the prevalence of b. miyamotoi and b. burgdorferi s.l. in questing ticks wa ... | 2017 | 27995301 |
| validation of droplet digital pcr for the detection and absolute quantification of borrelia dna in ixodes scapularis ticks. | we evaluated the qx200 droplet digital pcr (ddpcr™, bio-rad) system and protocols for the detection of the tick-borne pathogens borrelia burgdorferi and borrelia miyamotoi in ixodes scapularis nymphs and adults collected from north truro, massachusetts. preliminary screening by nested pcr determined positive infection levels of 60% for b. burgdorferi in these ticks. to investigate the utility of ddpcr as a screening tool and to calculate the absolute number of bacterial genome copies in an infec ... | 2017 | 27806739 |
| detection and characterization of the emerging relapsing fever pathogen, borrelia miyamotoi, from the ixodes ricinus tick in the rural trakya (thrace) region of northwestern turkey. | the hard tick-borne relapsing fever agent, borrelia miyamotoi infection in ixodes ricinus ticks sampled from istanbul and the countryside of kirklareli in northwestern turkey, was examined by taqman-pcr targeting 16s rdna, nested pcr targeting 16s rdna, the flagellin gene (flab), and the 16s and 23s rdna intergenic spacer (igs), and sequencing analyses of these amplicons. b. miyamotoi was detected in 1 out of 248 i. ricinus ticks (infection rate 0.4%). the tick infected with b. miyamotoi was col ... | 2016 | 27788060 |
| hard tick relapsing fever caused by borrelia miyamotoi in a child. | a 5-year-old massachusetts resident developed hard tick-borne relapsing fever caused by borrelia miyamotoi. a partially engorged ixodes scapularis tick was removed from her scalp and identified as infected with b. miyamotoi using polymerase chain reaction. two weeks later, she developed an illness compatible with b. miyamotoi infection that included fatigue and recurrent fever. the diagnosis was confirmed by b. miyamotoi seroconversion. | 2016 | 27626914 |
| occurrence of borrelia burgdorferi sensu lato in ixodes ricinus ticks with first identification of borrelia miyamotoi in vojvodina, serbia. | lyme borreliosis is the most common tick-borne infectious disease in eurasia. borrelia miyamotoi is the only known relapsing fever borrelia group spirochete transmitted by ixodes species. the aim of this study was to investigate the presence of lyme borrelia spp. and relapsing fever borrelia spp. in ixodes ricinus ticks collected from dogs and the vegetation from different parts of vojvodina, serbia. a total of 71 ixodes ricinus ticks were collected and screened for the presence of lyme borrelia ... | 2016 | 27574731 |
| laboratory cultivation and maintenance of borrelia miyamotoi. | borrelia miyamotoi is a relapsing fever tick-borne pathogen found in ixodes spp. (hard) ticks. in vitro culturing has proven difficult despite initial reports of cultures maintained in barbour-stoenner-kelly-ii (bsk-ii) medium. the ability to culture in vitro opens many avenues for investigating the genetics and physiology of bacterial species. this unit describes methods for the maintenance and cultivation of b. miyamotoi in liquid medium. © 2016 by john wiley & sons, inc. | 2016 | 27517334 |
| paired real-time pcr assays for detection of borrelia miyamotoi in north american ixodes scapularis and ixodes pacificus (acari: ixodidae). | borrelia miyamotoi is an emerging, tick-borne human pathogen. in north america, it is primarily associated with ixodes scapularis and ixodes pacificus, two species known to bite humans. here we describe the development and evaluation of a pair of real-time taqman pcr assays designed to detect b. miyamotoi in north american ticks. we sought to achieve sensitivity to b. miyamotoi strains associated with ticks throughout north america, the full genetic diversity of which is unknown, by targeting se ... | 2016 | 27475875 |
| insights into borrelia miyamotoi infection from an untreated case demonstrating relapsing fever, monocytosis and a positive c6 lyme serology. | we describe a patient from the united states with pcr- and serology-confirmed borrelia miyamotoi infection who recovered without antibiotics. our findings suggest that b. miyamotoi infection may cause relapsing fever, blood monocytosis and antibody reactivity to the c6 peptide. further studies are required to better define the spectrum of clinical and laboratory findings for this emerging tick-transmitted infection. | 2016 | 27412815 |
| borrelia miyamotoi: a human tick-borne relapsing fever spirochete in europe and its potential impact on public health. | borrelia miyamotoi is a tick-borne bacterium which has only recently been identified in europe as a human pathogen causing relapsing fever and little is known about its local impact on human health. there are three types of b. miyamotoi: asian (siberian), european, and american. b. miyamotoi is transmitted by the same ixodes ricinus-persulcatus species complex, which also transmits b. burgdorferi s.l., the lyme borreliosis group. both borrelia groups are mostly maintained in natural rodent popul ... | 2016 | 27100337 |
| variable major proteins as targets for specific antibodies against borrelia miyamotoi. | borrelia miyamotoi is a relapsing fever spirochete in ixodes ticks that has been recently identified as a human pathogen causing hard tick-borne relapsing fever (htbrf) across the northern hemisphere. no validated serologic test exists, and current serologic assays have low sensitivity in early htbrf. to examine the humoral immune response against b. miyamotoi, we infected c3h/hen mice with b. miyamotoi strain lb-2001 expressing variable small protein 1 (vsp1) and demonstrated that spirochetemia ... | 2016 | 27076681 |
| [the blood coagulation system and microcirculatory disorders in ixodid tick-borne borreliosis caused by borrelia miyamotoi]. | to study blood coagulation and microcirculatory disorders as a possible cause of transient dysfunctions of organs (the kidney, liver, heart, lung, etc.) in patients with ixodid tick-borne borreliosis caused by borrelia miyamotoi (bmt). subjects and methods; twenty-four patients with lyme disease (ld) and 28 bmt patients treated at izhevsk city hospital (udmurtia) were examined in the study. platelet counts and the presence of d-dimers were determined; activated partial thromboplastin time, proth ... | 2015 | 26821412 |
| [relapsing (recurrent) disease caused by borrelia miyamotoi]. | to clarify the clinical, laboratory, and epidemiological characteristics of relapsing ixodes tick-borne borreliosis (itb) caused by borrelia miyamotoi. | 2015 | 26821411 |
| prevalence of borrelia miyamotoi in ixodes persulcatus in irkutsk city and its neighboring territories, russia. | adult ixodes persulcatus were collected in highly populated districts in irkutsk city, russia, and in popular recreational and professional areas in its neighboring territories. borrelia miyamotoi infection in i. persulcatus was examined using multiplex taqman-pcr targeting 16s rdna, and nested pcr and sequencing analyses targeting flab and 16s rdna. b. miyamotoi and lyme disease borrelia species were detected in 13 (infection rate, 2.9%) and 77 (17.3%) out of 445 i. persulcatus ticks, respectiv ... | 2016 | 26750571 |
| distribution and survival of borrelia miyamotoi in human blood components. | borrelia miyamotoi, the agent of relapsing fever, is a tick-borne spirochete first isolated in japan in 1994. since then, the spirochete has been detected in ticks globally, generally in the same vectors as the lyme disease agent. human infection has been reported in russia, europe, japan, and the united states, as influenza-like febrile illness. in addition, two cases of meningoencephalitis caused by b. miyamotoi have also been reported in immunocompromised patients. here we evaluate the abilit ... | 2016 | 26689144 |
| borrelia miyamotoi. in response. | | 2015 | 26666795 |
| borrelia miyamotoi. | | 2015 | 26666794 |
| probability of spirochete borrelia miyamotoi transmission from ticks to humans. | | 2015 | 26584357 |
| assessing the abundance, seasonal questing activity, and borrelia and tick-borne encephalitis virus (tbev) prevalence of ixodes ricinus ticks in a lyme borreliosis endemic area in southwest finland. | studies have revealed that ixodes ricinus (acari: ixodidae) have become more abundant and their geographical distribution extended northwards in some nordic countries during the past few decades. however, ecological data of tick populations in finland are sparse. in the current study, i. ricinus abundance, seasonal questing activity, and their borrelia spp. and tick-borne encephalitis virus (tbev) prevalence were evaluated in a lyme borreliosis endemic area in southwest finland, seili island, wh ... | 2016 | 26548608 |
| coexistence of borrelia burgdorferi s.l. genospecies within ixodes ricinus ticks from central and eastern poland. | the purpose of the study was to assess the prevalence and coinfection rates of borrelia burgdorferi sensu lato genotypes in ixodes ricinus (l.) ticks sampled from diverse localities in central and eastern regions of poland. in years 2009-2011, questing nymphs and adults of i. ricinus were collected using a flagging method at 18 localities representing distinct ecosystem types: urban green areas, suburban forests and rural woodlands. molecular detection of b. burgdorferi s.l. genospecies was base ... | 2015 | 26408587 |
| molecular identification of borrelia miyamotoi in ixodes ricinus from portugal. | borrelia miyamotoi, a relapsing fever spirochete, has been found recently in ixodes ricinus ticks; however, little is known about its spatial distribution and potential local impact on human health. a total of 640 ticks (447 nymphs and 193 adults) collected throughout portugal were analyzed using two nested pcr protocols, one targeting the flagellin gene and the other the internal transcribed space region between the 5s and the 23s rrna. as a result, b. miyamotoi was detected, for the first time ... | 2015 | 26273814 |
| a novel duplex real-time pcr permits simultaneous detection and differentiation of borrelia miyamotoi and borrelia burgdorferi sensu lato. | for simultaneous detection of borrelia miyamotoi (relapsing fever spirochete) and borrelia burgdorferi sensu lato, we have developed a duplex real-time pcr targeting the flagellin gene (flab; p41), a locus frequently used in routine diagnostic pcr for b. burgdorferi s.l. detection. | 2016 | 26168860 |
| borrelia miyamotoi: the newest infection brought to us by deer ticks. | | 2015 | 26053967 |
| borrelia miyamotoi disease in the northeastern united states: a case series. | the first recognized cases of borrelia miyamotoi disease (bmd) in north america were reported in the northeastern united states in 2013. | 2015 | 26053877 |
| update and commentary on four emerging tick-borne infections: ehrlichia muris-like agent, borrelia miyamotoi, deer tick virus, heartland virus, and whether ticks play a role in transmission of bartonella henselae. | emerging tick-borne infections continue to be observed in the united states and elsewhere. current information on the epidemiology, clinical and laboratory features, and treatment of infections due to ehrlichia muris-like agent, deer tick virus, borrelia miyamotoi sensu lato, and heartland virus was provided and critically reviewed. more research is needed to define the incidence and to understand the clinical and the laboratory features of these infections. there is also a growing need for the ... | 2015 | 25999230 |
| co-infections and transmission dynamics in a tick-borne bacterium community exposed to songbirds. | we investigated the transmission dynamics of a community of tick-borne pathogenic bacteria in a common european songbird (parus major). tick-naïve birds were infested with three successive batches (spaced 5 days apart) of field-collected ixodes ricinus nymphs, carrying the following tick-borne bacteria: rickettsia helvetica (16.9%), borrelia garinii (1.9%), borrelia miyamotoi (1.6%), anaplasma phagocytophilum (1.2%) and candidatus neoehrlichia mikurensis (0.4%). fed ticks were screened for the p ... | 2016 | 26627444 |
| human borrelia miyamotoi infection in the united states. | | 0 | 23323920 |
| borrelia miyamotoi and candidatus neoehrlichia mikurensis in ixodes ricinus ticks, romania. | | 0 | 26889789 |
| unique strain of borrelia miyamotoi in ixodes pacificus ticks, california, usa. | | 2016 | 27479523 |
| borrelia miyamotoi-associated neuroborreliosis in immunocompromised person. | borrelia miyamotoi is a newly recognized human pathogen in the relapsing fever group of spirochetes. we investigated a case of b. miyamotoi infection of the central nervous system resembling b. burgdorferi-induced lyme neuroborreliosis and determined that this emergent agent of central nervous system infection can be diagnosed with existing methods. | 2016 | 27533748 |