| effects of putative neurotransmitters on the motor activity of spirometra mansonoides. | 5-hydroxytryptamine (5-ht), epinephrine, and dopamine strongly stimulated the motor activity of larval spirometra mansonoides. by contrast, a cholinomimetic agent, arecoline, paralyzed the worms. there was some pharmacological specificity among the agonists but not with various antagonists. acetylcholinesterase activity was present in both larval and adult spirometra. | 1977 | 16995 |
| metabolic fate of cyanocobalamin taken up by spirometra mansonoides spargana. | analysis of tissue from spirometra mansonoides spargana has shown that cyanocobalamin (vitamin b12) is metabolized to adenosylcobalamin and hydroxocobalamin. no methylcobalamin was detected. when the tissues were examined for enzymes which are known to utilize coenzyme forms of vitamin b12, only methylmalonyl coa mutase, which requires adenosylcobalamin was found. the enzyme, tetrahydropteroylglutamate methyltransferase, which requires methylcobalamin as a cofactor, was not detected. a sizable p ... | 1977 | 18565 |
| the presence and possible function of methylmalonyl coa mutase and propionyl coa carboxylase in spirometra mansonoides. | both spargana and adult forms of spirometra mansonoides were shown to accumulate lactate, succinate, acetate, and propionate upon in vitro incubation. adults differed markedly from the spargana in that quantitatively the most significant products of the former were acetate and propionate while the latter formed primarily acetate and lactate. the adults accumulated approximately 32 times more propionate than the spargana per gram of tissue. in accord with this propionate formation, propionyl coa ... | 1977 | 21232 |
| a comparison of the metabolic effects of bovine growth hormone and growth factor from spirometra mansonoides on rat liver in vivo. | the effects of bovine growth hormone(gh) and spirometra growth factor (sgf) on the in vivo concentrationions of glycolytic and citricacid (tca) cycle intermediates in rat liver were investigated. the effects of these agents on the mitochondrial and cytoplasmic redox states, liver phosphorylation states, and adenylate kinase activity were also evaluated. the effects of sgf were studied in both normal and hypophysectomized rats,wheras gh effects ere examined only in hypophysectomized rats. grow ... | 1976 | 178881 |
| use of the unlabeled antibody immunohistochemical technique for the demonstration of mouse immunoglobulin on the surface of spirometra mansonoides taken from infected mice. | | 1977 | 321739 |
| studies on endoparasites of the black bear (ursus americanus) in the southeastern united states. | examination of 53 black bears (ursus americanus) from six states in the southeastern united states revealed at least 17 species of endoparasites, including sarcocystis sp., spirometra mansonoides (spargana), macracanthorhynchus ingens, ancylostoma caninum, arthrocephalus lotoris, baylisascaris transfuga, capillaria aerophila, capillaria putorii, crenosoma sp., cyathospirura sp., dirofilaria immitis, gnathostoma sp., gongylonema pulchrum, microfilariae, molineus barbatus, physaloptera sp. and str ... | 1978 | 418189 |
| chemotherapeutic effects of 4-isothiocyanato-4'-nitrodiphenylamine (c9333-go/cgp 4540) on infections with nematospiroides dubius, hymenolepis diminuta, hymenolepis nana and spirometra mansonoides. | 4-isothiocyanato-4'-nitrodiphenylamine possessed anthelmintic activity against nippostrongylus dubius and hymenolepis nana in mice and h. diminuta in rats as determined by both egg counts and recovery of parasites at autopsy. no activity was detected against the cestode. spirometra mansonoides, in cats. | 1979 | 421846 |
| comparison of the effects of the growth factor produced by spirometra mansonoides and growth hormone in diabetic-hypophysectomized rats: lipid composition. | the effects of bovine growth hormone and the growth factor produced by plerocercoid larvae of the tapeworm, spirometra mansonoides, on body growth and lipid composition in diabetic-hypophysectomized rats were compared. the diabetic-hypophysectomized control rats gradually lost weight throughout the experiment but both growth hormone and plerocercoids stimulated marked weight gains. growth hormone treatment resulted in a loss of depot fat from the epididymal fat pads and caused a reduction of liv ... | 1978 | 660377 |
| comparison of the effects of the growth factor produced by spirometra mansonoides and growth hormone in diabetic-hypophysectomized rats: lymphoid tissue. | growth and development of the thymus is dependent on secretions from the anterior pituitary, presumably growth hormone. diabetes mellitus is known to reduce immunological competence. these studies compare the effects of bovine growth hormone (bgh) and the growth factor produced by plerocercoid larvae of the tapeworm, spirometra mansonoides, on metabolism of lymphoid tissue, thymus and spleen, in hypophysectomized rats made diabetic with a single intraperitoneal injection of alloxan. whereas the ... | 1978 | 660378 |
| isolation of an acyl-coa carboxylase from the tapeworm spirometra mansonoides. | | 1978 | 697776 |
| tapeworms of the chaco boreal, paraguay, with two new species. | mathevotaenia paraguayae sp. n. is described from euphractus sexcinctus. it differs from m. didelphidis (rud.) in having a transverse cirrus pouch anterior to the vagina. monoecocestus mackiewiczi sp. n. was found in phyllotis sp. it differs from m. parcitesticulatus rego in having a much smaller scolex, a poral ovary, and a cirrus pouch 360 to 440 micrometers long. other species reported are taenia macrocystis, taenia omissa, spirometra mansonoides, spirometra gracilis, spirometra longicollis, ... | 1978 | 722040 |
| suppression of somatotrops in rats bearing spargana of spirometra mansonoides, an ultrastructural study. | | 1977 | 845734 |
| [identification of a new intermediate host of spirometra mansonoides mueller, 1935 in the area of porto alegre, rio grande do sul, brazil]. | | 1977 | 847256 |
| a lipogenic effect in intact male hamsters infected with plerocercoids of the tapeworm, spirometra mansonoides. | plerocercoids of the tapeworm, spirometra mansonoides, produce a potent growth stimulating substance which is active in several species of mammals. while most of the actions of the plerocercoid growth factor (pgf) are similar to those of growth hormone (gh), lipid metabolism is one area where their actions are not alike. this report demonstrates that plerocercoid infection not only stimulates growth of intact male hamsters but is lipogenic as well. the lipogenic effects of plerocercoid infection ... | 1977 | 886406 |
| effect of growth factors on hepatic drug metabolism in diabetic-hypophysectomized rats. | in vivo administration to diabetic-hypothysectomized rats of either the growth factor produced by the plerocercoid larvae of the tapeworm, spirometra mansonoides, or mammalian growth hormone caused inhibition of hepatic drug metabolism measured in vitro. | 1977 | 891831 |
| changes in hookworm distribution in surinam. | during the months may-july, 1974, a follow-up investigation was carried out on hookworm infections in dogs and cats in order to study changes in the hookworm distribution in surinam since 1967. fifty-two cats and 152 dogs were examined for the presence of helminths in the oesophagus, small intestine, coecum and heart. in total 15,942 helminths were isolated; most of these (14,006) were hookworms belonging to the species ancylostoma caninum, a. tubaeforme, a. ceylanicum and a. braziliense. the av ... | 1976 | 987625 |
| isolation and identification of a cobamide coenzyme from the tapeworm spirometra mansonoides. | a light-sensitive vitamin b12 derivative has been extracted from the adult cestode, spirometra mansonoides. this corrinoid was identified as the cobamide coenzyme, adenosylcobalamin, by its chromatographic, chemical, and spectral properties. | 1976 | 1003284 |
| on the occurrence of spirometra mansonoides in south america. | | 1975 | 1165564 |
| initial studies on the effects of the growth factor produced by plerocercoids of the tapeworm, spirometra mansonoides, on liver drug metabolism. | | 1975 | 1191344 |
| intestinal helminths in dogs and cats on the antillian islands aruba, curaçao and bonaire. | an investigation into the prevalence, identity and size of population of intestinal helminths in dogs and cats was carried out in the dutch antillian islands, curaçao, bonaire and aruba during april and may 1974. ninety-one dogs and 83 cats were examined. in all, 4,824 helminths were isolated and identified. the following species were isolated from dogs: dipylidium caninum (most frequent), ancylostoma caninum (frequent in curaçao), toxocara, taenia hydatigena and ancylostoma braziliense. species ... | 1975 | 1237955 |
| comparison of the uptake of vitamin b12 by spirometra mansonoides and hymenolepis diminuta and the functional groups of b12 analogs affecting uptake. | uptake of 57co-vitamin b12 (cn-cbl) by spargana (larvae) of the pseudophyllidean tapeworm, spirometra mansonoides, was affected by temperature, was saturable with respect to concentration of cn-cbl in the medium, and was inhibited in the presence of several structural analogs of cn-cbl. in uptake studies with various analogs it was found that chemical modifications which altered the benzimidazole moiety greatly reduced the ability of the worm to take up these analogs. modifications in which the ... | 1976 | 1255391 |
| growth stimulation of lymphatic tissue by plerocercoid larvae of the tapeworm, spirometra mansonoides. | | 1976 | 1278667 |
| intracerebral hematoma caused by sparganum: a case report. | cerebral sparganosis is caused by migrating larvae of spirometra mansonoides. this condition is rare. the presenting symptoms include headache, seizures and focal neurological deficit, which are due to a parasitic granulomatous space-occupying lesion. the authors report a case of intracerebral hematoma, which has never been reported as a presenting symptom of cerebral sparganosis. the surgical treatment of this complicated condition yielded poor results when compared to previous reports of the u ... | 1992 | 1306198 |
| comparison of isozyme patterns between spirometra erinacei and spirometra mansonoides by isoelectric focusing. | no differences were observed in the isozyme patterns of 4 enzymes examined between fresh samples stored at -80 c and samples stored at room temperature for 10 days after lyophilization, which supports the validity of comparing lyophilized samples to fresh frozen tissue. mature proglottids as well as plerocercoids of spirometra erinacei from japan and australia were indistinguishable by comparison of isozyme patterns after isoelectric focusing. the isozyme patterns of acid phosphatase, glucosepho ... | 1992 | 1386110 |
| a case of cerebral sparganosis in south america. | cerebral sparganosis (cs) is a parasitic infection caused by the larva of spirometra mansonoides. rarely it can affect the human brain. we report the case of a 24-year old man from paraguay who suffered from seizures and headache for one year. a frontal tumor was diagnosed by ct-scan and was subsequently resected. the pathological examination revealed a larva with sparganum characteristics. the evolution of the patient was satisfactory. as far as we know, this is the first case of cs reported in ... | 1991 | 1863236 |
| cerebral sparganosis caused by spirometra mansonoides. case report. | cerebral sparganosis is an uncommon parasitic zoonosis caused by the migrating larva of the genus spirometra mansonoides. the clinical and computerized tomography presentation, as well as the operative and histopathological findings, of the first known case in mexico are detailed. the dead larva elicited intense acute inflammation resulting in focal encephalitis. surgical removal of the larva yielded excellent results. | 1991 | 1869951 |
| cerebral sparganosis. case report. | the tapeworm spirometra mansonoides infects man worldwide, particularly in asian countries. rarely, the central nervous system is involved; such a case is presented here. in the total of 12 reported cases, including the case described, the worm presented clinically as a mass suspicious for neoplasm or chronic abscess cavity. surgical removal was invariably curative in each case. although infrequent, the possibility of tapeworm infection should be entertained in the evaluation of intracranial mas ... | 1990 | 2191089 |
| molecular characterization of the spirometra mansonoides genome: renaturation kinetics, methylation, and hybridization to human cdna probes. | high molecular weight dna from pleroceroid larvae of the tapeworm spirometra mansonoides was purified from isolated nuclei by conventional techniques. the dna so isolated has a melting temperature (tm) of 87 degrees c and a guanine plus cytosine (g/c) content of 44%. 5-methyl cytosine could not be detected in plerocercoid dna by hplc analysis of dna hydrolysates, by radiolabeling 5'-termini of mspi digests with polynucleotide kinase, or by comparing restriction patterns generated by mspi and hpa ... | 1990 | 2364105 |
| in vitro insulin-like actions of the growth factor from the tapeworm, spirometra mansonoides. | in vitro actions of purified plerocercoid growth factor (pgf) were compared with those of insulin and human growth hormone (hgh) in adipose tissue from normal male rats. insulin-like effects were measured by the ability of pgf, insulin, or hgh to stimulate oxidation of [u-14c]glucose to 14co2, to stimulate lipogenesis, and to inhibit epinephrine-induced lipolysis. pgf and insulin stimulated significant increases in glucose oxidation and lipogenesis in adipose tissue that had not been preincubate ... | 1989 | 2492669 |
| intestinal adaptation in short-bowel syndrome. | after massive resection of the small intestine the remnant mucosa has an important capacity to enlarge the absorptive surface for the digestion, hydrolysis and absorption of nutrients. this intestinal adaptation is achieved by the interaction of various factors. oral nutrients together with pancreatic biliary secretions stimulate the mucosa to become hyperplastic. secondary to these luminal factors hormones play an important role in the adaptive process. among the hormones, enteroglucagon is the ... | 1989 | 2651129 |
| significance of the distribution of 57co-vitamin b12 in spirometra mansonoides (cestoidea) during growth and differentiation in mammalian intermediate and definitive hosts. | the distribution of labeled cyanocobalamin (cn-[57co]cbl = [57co]-vitamin b12) in pleurocercoids and adult tapeworms of spirometra mansonoides was studied during development in mice 22 days days pi, respectively. plerocercoid scolices, obtained by cutting away their bodies or by in vitro enzymatic dissolution of the bodies, were pulsed with cn- magnitude of 57co cbl for 1h at 37 degrees c and reimplanted subcutaneously into mice or given per os to cats. in regenerated plerocercoids, the highest ... | 1989 | 2707957 |
| the growth factor from plerocercoid larvae of the tapeworm, spirometra mansonoides, stimulates growth but is not diabetogenic. | a factor produced by plerocercoids of the tapeworm spirometra mansonoides is similar to human growth hormone (hgh) in that it stimulates body growth, binds to hgh receptors, cross-reacts with anti-hgh antibodies, and has lactogenic and insulin-like activities. the purpose of this study was to determine whether plerocercoid growth factor (pgf) is similar to hgh in expressing diabetogenic activity in the genetically obese (ob/ob) mouse. to determine an effective dose for use in the obese mice, the ... | 1989 | 2726784 |
| reduction of lactogenic receptors in female hamster liver due to the human growth hormone analog produced by plerocercoids of the tapeworm, spirometra mansonoides. | the inductive effect of gh on hepatic lactogenic receptors is suspected of being due to a direct somatogenic action. plerocercoid larvae of the tapeworm, spriometra mansonoides, produce a factor that stimulates body growth, suppresses endogenous gh, and specifically displaces [125i]human (h) gh from hepatic receptors. plerocercoid growth factor (pgf) mimics the growth-promoting actions of gh, but it has not been shown to duplicate all of the activities reported for gh. an important function of g ... | 1986 | 3004894 |
| regression of rat mammary tumors associated with suppressed growth hormone. | serum growth hormone (gh) was suppressed in female rats bearing mammary tumors induced by 7, 12, dimethylbenz(a)anthracene (dmba) or n-nitrosomethylurea(nmu). serum gh was suppressed due to treatment with a human gh analog produced by the plerocercoid stage of the tapeworm spirometra mansonoides. rats treated with plerocercoid growth factor (pgf) via plerocercoid infection had accelerated growth rates despite marked reductions in gh levels. approximately two-thirds of the mammary tumors induced ... | 1986 | 3019224 |
| use of receptor affinity chromatography in purification of the growth hormone-like factor produced by plerocercoids of the tapeworm spirometra mansonoides. | the plerocercoid stage of the tapeworm spirometra mansonoides produces a functional analog of human growth hormone (hgh). among the similarities between plerocercoid growth factor (pgf) and hgh is competition for the same receptors on rabbit liver membranes. to take advantage of this characteristic in a purification scheme for pgf, rabbit liver microsomes were solubilized in triton x-100 and the hgh receptors were purified over an hgh affinity column. the purified receptors from six rabbit liver ... | 1988 | 3392699 |
| the growth hormone-like factor produced by the tapeworm spirometra mansonoides specifically binds receptors on cultured human lymphocytes. | plerocercoid larvae of the tapeworm spirometra mansonoides produce a factor with activities similar to those of growth hormone (gh). highly selective receptors for gh have been described on cultured human lymphocytes (im-9 cells) and these cells have been used as a model of binding essentially restricted to human gh (hgh). we compared the displacement of [125i]hgh by hgh and partially purified plerocercoid growth factor (pgf) in assays using rabbit hepatic membranes and im-9 cells. pgf displaced ... | 1988 | 3418464 |
| in vitro and in vivo enzymatic dissolution of the plerocercoid body of spirometra mansonoides (cestoidea). | | 1987 | 3429122 |
| tegument galactosylceramides of the cestode spirometra mansonoides. | the brush border-like surface of the tegument of the adult and the plerocercoid larva of a pseudophyllidean cestode, spirometra mansonoides, has been shown to contain hydroxylated galactosylceramides. d-galactosyl-n-(2-d-hydroxyoctadecanoyl)-d-phytosphingosine, d-galactosyl-n-(2-d-hydroxyoctadecanoyl)-d-dihydrosphingosine and d-galactosyl-n-(octadecanoyl)-d-phytosphingosine were identified as major glycosphingolipids in a tegumental plasma membrane fraction with associated microtriches, by combi ... | 1987 | 3431569 |
| separation and functions of two acyl coa transferases from ascaris lumbricoides mitochondria. | many invertebrates accumulate propionate, or products derived from propionate, as products of fermentation. evidence has been reported that the nematode, ascaris suum, the cestode, spirometra mansonoides, and the trematode, fasciola hepatica, accumulate propionate by means of an adenosine triphosphate (atp)-generating decarboxylation of succinate. to generate energy, an acyl coenzyme a (coa) transferase that would transfer coa to succinate is required as one component of the sequence of reaction ... | 1987 | 3475402 |
| some biochemical effects of the growth hormone analogue produced by plerocercoids of the tapeworm spirometra mansonoides on carbohydrate metabolism of adipose tissue from normal, diabetic, and hypophysectomized rats. | plerocercoids of spirometra mansonoides produce a functional analogue of mammalian growth hormone (gh). plerocercoid growth factor (pgf) mimics the growth-promoting actions of gh, but has not been shown to duplicate all of the actions reported for gh. the purpose of this study was to determine the effects of plerocercoid infection (chronic pgf treatment) on glucose metabolism of adipose tissue and to compare the effects to those elicited by insulin and gh in intact, diabetic, and hypophysectomiz ... | 1986 | 3537254 |
| insulin-like effects in the rat of the purified growth factor from spirometra mansonoides plerocercoids. | the acute effects of injections of the human growth hormone-like factor purified from plerocercoids of the tapeworm spirometra mansonoides on carbohydrate, lipid, and protein metabolisms were determined in intact rats. male rats were injected ip with saline, insulin, or various doses of partially purified pgf. the rats injected with insulin had significantly reduced serum glucose concentrations but no dose of pgf caused a change in serum glucose levels. insulin and pgf stimulated [14c]glucose an ... | 1987 | 3554256 |
| suppression of receptors for prolactin and estrogen in rat liver due to treatment with the growth hormone analogue produced by the tapeworm spirometra mansonoides. | somatogenic hormones play an important role in regulation of receptors for prolactin (prl) and estrogen. plerocercoids of the tapeworm, s. mansonoides produce a factor which mimics some, but not all of the actions reported for gh. intact female rats were subjected to a constant infusion of plerocercoid growth factor (pgf) via a subcutaneous infection for two weeks to determine if pgf influences receptors for prl, gh or estradiol. the rate of weight gain in the pgf-treated rats was accelerated in ... | 1986 | 3585861 |
| anthelmintic efficacy of ivermectin in naturally parasitized cats. | ivermectin was administered per os [( po]; n = 15) or subcutaneously [( sc]; n = 3) to naturally parasitized cats at 10 (n = 6), 100 (n = 6), or 300 (n = 6) micrograms/kg of body weight. nontreated control cats were given sterile isotonic saline solution po (n = 5) or sc (n = 1). qualitative fecal examinations were performed on each cat 1 day before treatment and 14 days after treatment. cats were euthanatized 14 days after treatment, at which time parasites from the gastrointestinal tracts were ... | 1987 | 3592364 |
| augmentation of postresection mucosal hyperplasia by plerocercoid growth factor (pgf). analog of human growth hormone. | postresection villus hyperplasia is a major compensatory mechanism in the short-bowel patient. substances capable of augmenting postresection mucosal hyperplasia could have therapeutic implications. human growth hormone (hgh) and human growth hormone releasing factor (hghrf) stimulate growth of the gastrointestinal tract; however, the diabetogenic actions of growth hormone limit its usefulness in clinical practice. plerocercoid larvae of the tapeworm spirometra mansonoides produce an analog of h ... | 1987 | 3665682 |
| antihuman growth hormone (gh) antibodies cross-react with the gh-like factor from plerocercoids of the tapeworm spirometra mansonoides. | a factor produced by the plerocercoid stage of s. mansonoides mimics some, but not all, of the actions reported for hgh. the biological actions of plerocercoid growth factor (pgf) suggest structural similarity to human gh (hgh). plerocercoid membranes were solubilized, and pgf was purified more than 1000-fold by hgh receptor affinity chromatography. the ability of purified pgf to displace [125i]hgh from monoclonal antibodies specific for four distinct nonoverlapping antigenic determinants of hgh ... | 1987 | 3665849 |
| cerebral sparganosis. | cerebral sparganosis is caused by the migrating larva of spirometra mansonoides. only seven cases have been reported worldwide. we here report the second known case in the united states. including our case, ages ranged from 24 to 46 years. men and women were equally affected. headache, convulsions, focal neurologic signs, and peripheral eosinophilia were common. ct often revealed an enhancing mass. surgical resection of the parasitic granuloma gave excellent results. often revealed an enhancing ... | 1986 | 3748393 |
| enhanced growth of a polyoma transformed tumor cell in spirometra mansonoides-infected hamsters. | | 1973 | 4352534 |
| failure of oriental spargana to immunize the hypophysectomized rat against the sparganum growth factor of spirometra mansonoides. | | 1972 | 4627887 |
| in vitro preparation of a growth factor from plerocercoids of the tapeworm, spirometra mansonoides. | | 1973 | 4689366 |
| responses in hypophysectomized rats implanted with plerocercoids of the tapeworm, spirometra mansonoides. | | 1973 | 4703417 |
| pigeon crop sac stimulation due to a factor produced by plerocercoids of the tapeworm, spirometra mansonoides. | | 1973 | 4703419 |
| cultivation of the sparganum of spirometra mansonoides in vitro with prolonged production of sparganum growth factor. | | 1973 | 4709010 |
| a culture method permitting in vitro growth of spirometra mansonoides spargana. | | 1973 | 4744525 |
| growth responses in thyroidectomized, hypophysectomized and alloxan diabetic rats infected with plerocercoids of the tapeworm, spirometra mansonoides. | | 1973 | 4745524 |
| isolation by polyacrylamide gel electrophoresis of the growth factor from plerocercoids of the tapeworm, spirometra mansonoides. | | 1973 | 4747652 |
| brush border development in the tegument of the tapeworm, spirometra mansonoides. | | 1974 | 4821105 |
| biological properties of the growth hormonelike factor from the plerocercoid of spirometra mansonoides. | | 1971 | 4947771 |
| feedback inhibition of pituitary growth hormone in rats infected with spirometra mansonoides. | | 1972 | 5059039 |
| stimulation of ornithine decarboxylase activity in rat tissues by growth hormone and by serum growth factor from rats infested with spargana of spirometra mansonoides. | | 1972 | 5082506 |
| the effect of the implantation of spirometra mansonoides spargana in the growing rat. | | 1971 | 5118474 |
| growth hormone-like activity in hypophysectomized rats implanted with spirometra mansonoides spargana. | | 1970 | 5412344 |
| induction of sulfation factor activity infection of hypophysectomized rats with spirometra mansonoides. | | 1971 | 5542419 |
| growth stimulation induced by infection with spirometra mansonoides spargana in propylthiouracil-treated rats. | | 1968 | 5641051 |
| acquired immunity in mice to infection with the cestode spirometra mansonoides. | | 1969 | 5764040 |
| lipid metabolism in the larval and adult forms of the tapeworm spirometra mansonoides. | | 1966 | 5924644 |
| the laboratory propagation of spirometra mansonoides (mueller, 1935) as an experimental tool. vii. improved techniques and additional notes on the biology of the cestode. | | 1966 | 5949613 |
| insulin-like activity from the sparganum of spirometra mansonoides. | | 1967 | 6067416 |
| a method for solubilization of a human growth hormone analogue from plerocercoids of spirometra mansonoides. | | 1984 | 6096528 |
| succinate decarboxylation to propionate and the associated phosphorylation in fasciola hepatica and spirometra mansonoides. | the trematode, fasciola hepatica, and the cestode, spirometra mansonoides have been shown to be similar to the nematode ascaris lumbricoides in that all three decarboxylate succinate to propionate plus co2. associated with this decarboxylation is an incorporation of 32pi into organic phosphate. both the decarboxylation and phosphorylation are markedly stimulated by the addition of propionyl-coa, are dependent on coenzyme b12 and are inhibited by avidin. the trematode and cestode exhibit propiony ... | 1981 | 6114429 |
| internal transport and metabolism of cobalamin in spirometra mansonoides (cestoda) spargana. | the anterior 2 mm of the sparganum of spirometra mansonoides contained 35 to 48% of the total endogenous cobalamin (cbl) with only 2 to 4% in the terminal 1 cm. [57co]cobalamin taken up in the posterior region of spargana was transported directionally to the anterior region and concentrated there resulting in a uniform depletion of [57co]cbl along the remaining body length. the anterior 2 mm contained 24% of the sparganum's holo-mmcoam activity with only 5% in the terminal 1 cm. when head and bo ... | 1982 | 6129295 |
| insulin-like effects of fatty acid synthesis in liver of hamsters infected with plerocercoids of the tapeworm, spirometra mansonoides. | elevated serum lipids are associated with infections of laboratory rodents with plerocercoids of spirometra mansonoides. the effect of infection with these larval tapeworms on triglyceride degradation and hepatic de novo fatty acid synthesis was investigated in syrian hamsters. serum lipoprotein electrophoresis revealed a consistent elevation in very low density lipoproteins in the infected animals. lipoprotein lipase activity was enhanced in the infected animals. after seven days of plerocercoi ... | 1984 | 6143778 |
| spirometra mansonoides: effects of plerocercoid infection on glycogen deposition in rats. | the effects of infection with plerocercoids of spirometra mansonoides on tissue glycogen deposition of rats was determined. hypophysectomized rats infected for two days had higher liver glycogen concentrations than controls and this effect was greatest after one week. elevated liver glycogen associated with plerocercoid infection was observed in fed animals both at the beginning and at the end of the light period as well as after an overnight fast. glycogen phosphorylase (1,4 alpha d glucan: ort ... | 1982 | 6300217 |
| delay of puberty onset in males due to suppression of growth hormone. | infection with spirometra mansonoides at 22 days of age was associated with delayed sexual maturation in the male rat. balanopreputial separation occurred at 46.7 +/- 0.8 days in controls and at 50.6 +/- 0.9 days in worm-treated rats (p less than 0.02). this was accompanied by a delay in the normal prepubertal testicular and seminal vesicle weight increases. lh remained normal but serum fsh was depressed as early as 25 days of age. the castration response in worm-treated rats was comparable to t ... | 1983 | 6406925 |
| endoparasites and selected infectious agents in bobcats (felis rufus) from west virginia and georgia. | a total of 143 bobcats (felis rufus) from west virginia and 10 bobcats from georgia was examined for parasites and selected infectious agents. a total of 31 species of parasites was recovered including 1 protozoan, 1 trematode, 4 cestodes, 1 acanthocephalan and 24 nematodes. results indicate bobcats are important definitive hosts for sarcocystis sp. and toxoplasma gondii. thirteen species (paragonimus kellicotti, spirometra mansonoides, taenia macrocystis, t. rileyi, capillaria putorii, toxascar ... | 1981 | 6802988 |
| characterization of cobalamin receptor sites in brush-border plasma membranes of the tapeworm spirometra mansonoides. | the interaction of receptor sites in microtriches (brush-border) membranes isolated from the sparganum (larva) of the cestode (tapeworm) spirometra mansonoides with [57co]cyanocobalamin (cn-[57co]cbl) has been characterized on the basis of the following criteria: time dependence, reversibility, high-affinity binding, finite binding capacity, and ligand specificity. the association of cn-[57co]cbl to isolated microtriches membranes at 22 degrees c reached equilibrium in approximately 90 min. the ... | 1983 | 6833256 |
| spirometra mansonoides: lectin analysis of tegumental glycopeptides. | | 1982 | 6896496 |
| immunological aspects associated with suppression of hormone levels in rats infected with plerocercoids of spirometra mansonoides (cestoda). | the effect of the plerocercoid larvae of spirometra mansonoides on hormone levels and the immune system of intact and hypophysectomized (hx) rats was studied. intact rats exhibited a decrease in serum growth hormone (gh) and thyroxine (t4) concentrations and a suppression of the humoral immune response 2 wk postinfection. at 4 and 9 wk postinfection, hormone concentrations and the humoral immune response returned to normal levels in the rats. when rats were infected with plerocercoids and then r ... | 1982 | 7175621 |
| the lipogenic effect of the growth factor produced by plerocercoids of the tapeworm, spirometra mansonoides, is not the result of hypothyroidism. | plerocercoid larvae of the tapeworm, spirometra mansonoides produce a growth hormone-like factor that stimulates body growth of a variety of normal and hormone-deficient animals. plerocercoid infection (15 per hamster) stimulated an increase in body weight, and markedly suppressed pituitary weight and growth hormone (gh) concentrations of serum and pituitaries of syrian hamsters. the suppression of serum gh persisted for at least 4 mo after the initiation of infection. the presence of plerocerco ... | 1982 | 7175622 |
| location of carbohydrate in the tegument of the procercoid of spirometra mansonoides. | carbohydrate distribution within vesicles of the tegumental cytoplasm of the procercoid of spirometra mansonoides indicated that there are at least three morphologically and histochemically different vesicular types, but only one vesicular type was present in the subtegumental perikarya. this distribution of vesicles and the presence of morphologically intermediate forms could represent either the discontinuous, sequential synthesis of the various vesicular types or continued differentiation of ... | 1981 | 7264826 |
| lipids of stages in the life-cycle of the cestode spirometra mansonoides. | the kinds and amounts of the lipids of each stage (egg, coracidium, procercoid, plerocercoid, adult) in the life-cycle of the cestode spirometra mansonoides, and of environmental lipids, have been examined by combinations of teae-cellulose and silicic acid column, silica gel thin-layer and scot column gas-liquid chromatography. major lipids of all stages were triacylglycerols, cholesterol, diphosphatidylglycerol, phosphatidylethanolamine, phosphatidylserine, phosphatidylinositol, and phosphatidy ... | 1980 | 7442717 |
| benzoquinones in stages of the life-cycle of the cestode spirometra mansonoides. | ubiquinone-10 and rhodoquinone-10 were detected in stages of the life-cycle of a pseudophyllidean cestode, spirometra mansonoides, by chromatographic, uv spectrophotometric, proton nuclear magnetic resonance spectrometric and electron impact mass spectrometric methods. ubiquinone-10 was identified in 1-day-old eggs and coracidia, and rhodoquinone-10 in coracidia, plerocercoids and adult tapeworms. tentative identification were also made of ubiquinone-10 in procercoids and rhodoquinone-10 in 10-d ... | 1980 | 7442718 |
| intraventricular haemorrhage and hydrocephalus caused by intraventricular parasitic granuloma suggesting cerebral sparganosis. | a 67-year-old female farmer presented with acute loss of consciousness. computed tomograms showed a calcified mass in the cavum septi pellucidi with intraventricular haemorrhage and obstructive hydrocephalus. the patient became fully conscious after urgent external ventriculostomy and subsequently underwent craniotomy for the excision of the mass. pathological examination of the mass demonstrated a granuloma surrounding a degenerating larva compatible with spirometra mansonoides whose mimicking ... | 1994 | 7847165 |
| the growth factor from plerocercoids of spirometra mansonoides is both a growth hormone agonist and a cysteine proteinase. | plerocercoids of the tapeworm spirometra mansonoides produce a substance that stimulates growth of experimental hosts. we report purification of plerocercoid growth factor (pgf) to homogeneity by a process involving isolation and solubilization of plerocercoid membranes, isoelectric point selection by chromatofocusing chromatography or preparative isoelectric focusing, and anion-exchange chromatography. a radioreceptor assay (rra) for human growth hormone (hgh) was used to detect pgf and purity ... | 1996 | 8604085 |
| an unusual host-parasite relationship: the growth hormone-like factor from plerocercoids of spirometrid tapeworms. | accelerated body growth is associated with experimental infections with the plerocercoid stage of the pseudophyllidean tapeworm, spirometra mansonoides. the growth response is due to a protein that is synthesized and released by plerocercoids in the host. plerocercoid growth factor (pgf) is transported by the blood, interacts with growth hormone (gh) receptors and mimics many of the biological actions of gh. purification and characterization of pgf reveals that the gh-like factor is a 27.5 kda c ... | 1996 | 8875304 |
| the laboratory propagation of spirometra mansonoides as an experimental tool. i. collecting, incubation and hatching of the eggs. | | 1959 | 13673337 |
| natural infections of spirometra mansonoides in new jersey cats. | | 1964 | 14215491 |
| in vitro cultivation of spirometra mansonoides (cestoda) from the procercoid to the early adult. | | 1964 | 14244799 |
| biochemical changes in mice infected with spargana of the cestode, spirometra mansonoides. | | 1965 | 14339360 |
| food intake and weight gain in mice parasitized with spirometra mansonoides. | | 1965 | 14339361 |
| the laboratory propagation of spirometra mansonoides (mueller, 1935) as an experimental tool. iii. in vitro cultivation of the plerocercoid larva in a cellfree medium. | | 1959 | 14424954 |
| the laboratory propagation of spirometra mansonoides as an experimental tool. v. behavior of the sparganum in and out of the mouse host, and formation of immune precipitates. | | 1961 | 14476916 |
| the laboratory propagation of spirometra mansonoides as an experimental tool. iv. experimental inversion of the primary axis in the developing egg. | | 1961 | 14476917 |
| plerocercoid growth factor: a homologue of human growth hormone. | plerocercoids of the tapeworm, spirometra mansonoides, produce a factor with characteristics similar to those of mammalian growth hormone (gh). plerocercoid growth factor (pgf) stimulates growth and mimics other actions of gh but does not possess the anti-insulin/diabetogenic activities intrinsic to mammalian growth hormones. duplication of activities unique to human gh, chemical and physical similarities, plus crossreactivity with strictly specific anti-hgh monoclonal antibodies, underlie the h ... | 1987 | 15462883 |
| gastrointestinal helminths of free-ranging florida panthers (puma concolor coryi) and the efficacy of the current anthelmintic treatment protocol. | thirty-five florida panthers (puma concolor coryi [bangs, 1899]) collected from six counties in southern florida between 1978 and 2003 were examined at necropsy for gastrointestinal helminths. the panthers were placed into two groups: 1) treated with anthelmintics (n = 17), and 2) untreated (n = 18). nine species of helminths (one trematode, six nematodes, and two cestodes) were identified in the untreated panthers. the most prevalent helminths were alaria marcianae (larue, 1917) (100%), spirome ... | 2006 | 16870865 |
| [human plerocercoidosis and sparganosis: i. a historical review on aetiology]. | plerocercoid should not be confused with sparganum. the scolex of plerocercoid has a bothrium or bothrial slit but there is no true scolex in sparganum. plerocercoid is a developmental stage of an animal tapeworm, genus spirometra. sparganum is another generic name of a pseudophyllidean cestode. plerocercoid causes benign plerocercoidosis and sparganum causes "malignant sparganosis". plerocercoidosis is a parasitic zoonosis which can be food-borne, water-borne, contact-borne or mother-borne. dur ... | 2009 | 19459502 |
| survey of helminth parasites of cats from the metropolitan area of cuiabá, mato grosso, brazil. | besides presenting zoonotic potential, helminths of cats are responsible for gastrointestinal, hepatic, and pulmonary diseases. in order to identify the helminthic fauna, prevalence, mean intensity of parasitism (mip), and mean abundance population (map), 146 cats from the metropolitan area of cuiabá, midwestern brazil, were necropsied. in 98 these animals, 12 species of helminths were identified, comprising (species, prevalence, mip, and map, respectively): nematodes (ancylostoma braziliense [5 ... | 2013 | 23856737 |
| sparganosis of liver: a rare entity and review of literature. | humans are known to serve as the secondary intermediate host for some larval forms of canine or feline tapeworms. sparganosis is caused by plerocercoid larva of spirometra of which there are three main species; spirometra mansoni (or spirometra erinaceieuropaei), spirometra mansonoides and spirometra proliferum. a one-and-half-year-old patient presenting with febrile illness was diagnosed radiologically as a case of liver abscess. the aspirate from the abscess cavity had a thin thread-like worm ... | 2012 | 23220827 |
| molecular detection of spirometra decipiens in the united states. | the genus spirometra belongs to the family diphyllobothriidae and order pseudophyllidea, and includes intestinal parasites of cats and dogs. in this study, a plerocercoid labeled as spirometra mansonoides from the usa was examined for species identification and phylogenetic analysis using 2 complete mitochondrial genes, cytochrome c oxidase i (cox1) and nadh dehydrogenase subunit 3 (nad3). the cox1 sequences (1,566 bp) of the plerocercoid specimen (usa) showed 99.2% similarity to the reference s ... | 2016 | 27658603 |
| [stereotactic aspiration of spirometra mansonides larvae]. | brain sparganosis is a non-common parasite infection by diphyllobothrium or spirometra mansonoides larvae. this last one is responsible for most of the infestations in humans. we report a 19 years male patient bearer of a brain sparganosis. the patient presented with headache and left hemiparesis. ct diagnosis of right thalamic lesions was made and aspiration biopsy was performed using stereotactic system, obtaining a whole and death larvae. histopathology confirms a cns parasitism and it was tr ... | 2015 | 26436792 |
| [ocular infestation by plerocercoid of spirometra mansonoides: first case report in peru]. | plerocercoidosis is a parasitic zoonosis caused by plerocercoid larvae of the genus spirometra. the larvae migrate through the intestinal wall tissue, by subcutaneous route and can reach different areas of the body like the head, the brain and the eye socket. a case is reported of a 45 year-old man from the peruvian amazon with burning sensation associated with conjunctival edema and hemorrhage in the outer eye border of the right eye for eleven months. a localized worm in the right orbital cavi ... | 2015 | 26338404 |