| variable response of normal and transformed mouse cells to interferon inducers. | balb/3t3 mouse cells, normal and sv40-transformed, produced interferon when induced with newcastle disease and influenza viruses; transformed cells failed to respond to double-stranded rna inducers. | 1976 | 7948 |
| eyach--an arthropod-borne virus related to colorado tick fever virus in the federal republic of germany. | from ixodes ricinus ticks collected in a tick-borne encephalitis focus in baden-württemberg, an agent pathogenic exclusively for suckling mice was isolated. obviously a virus, it passed membrane filters with a pore width of 200 nm. it was resistant to ether and sodium deoxycholate, but not to chloroform. in the complement fixation test it showed a close, and in the neutralisation test a more one-sided relationship to colorado tick fever virus. | 1976 | 9824 |
| tick-borne diseases in the united states: rocky mountain spotted fever and colorado tick fever. a review. | the historical, clinical, ecological, and epidemiological features of rocky mountain spotted fever and colorado tick fever, the two important tick-borne diseases in the united states, are reviewed. rocky mountain spotted fever, once considered a disease of the past, has again become a measurable public health problem. its nationwide incidence has steadily increased since 1960 and has reached record proportions in 1976. the various factors responsible for this trend as well as for the mortality r ... | 1977 | 19954 |
| international arbovirus research. | international cooperation in arbovirus research became increasingly prominent shortly after it was found in the early 1940's, that antigenic relationships existed among certain viruses isolated in different areas of thw world. the interest of a number of scientists and of a private organization led to the establishment of an international information exchange and to the preparation of an international catalogue of arboviruses including certain other viruses of vertebrates. international cooperat ... | 1975 | 173936 |
| immunoperoxidase staining for detection of colorado tick fever virus, and a study of congenital infection in the mouse. | indirect immunoperoxidase (ip) staining was evaluated for sensitivity and specificity in detecting colorado tick fever (ctf) virus antigen in infected cell cultures and infected mouse tissues, and then was applied to a study of congenital ctf infection in mice. the sensitivity of ip staining was comparable to that of immunofluorescence staining in detecting ctf antigen in infected cell cultures. endogenous peroxidase activity of mouse tissues caused nonspecific reactivity in the ip system, but t ... | 1979 | 223460 |
| discriminant analysis: a method of identifying foci of vector-borne diseases. | identification of foci of vector-borne diseases does not require knowledge of exact abundances of vectors and pathogens; rather, a focus is defined by the presence, or some minimal level of abundance, of a vector and pathogen. stepwise discriminant analysis (da) was applied to data on free-ranging adult wood ticks (the vector) and to data on isolations of colorado tick fever virus from small mammals. trap stations were grouped on the basis of relative abundance of wood ticks for one set of analy ... | 1979 | 223462 |
| [orbiviruses]. | | 1979 | 229658 |
| the development of colorado tick fever virus within cells of the haemopoietic system. | electron microscopic examination of haemopoietic liver tissue from mice infected in utero or when newborn showed inclusions of colorado tick fever virus within erythroblasts, reticulocytes and erythrocytes. inclusions were also seen within erythroblastoid cells undergoing mitosis. other evidence of virus replication within erythropoietic cells was the presence of intracytoplasmic and intranuclear fibres, which have been shown to be associated with colorado tick fever virus replication. the findi ... | 1978 | 641533 |
| teratogenic effects of colorado tick fever virus in mice. | the teratogenic effects in mice of colorado tick fever (ctf) virus, a human pathogen, were demonstrated. various routes of inoculation, gestational periods, and dosages of virus were studied. the incidence of stillbirth and neonatal death increased significantly after inoculation of pregnant mice with ctf virus. ctf virus crossed the placenta and replicated to high titers in the placental and fetal tissues. mice that survived the first six weeks of life had neutralizing antibody to ctf virus. ne ... | 1975 | 1117196 |
| contributions to the ecology of colorado tick fever virus. 2. population dynamics and host utilization of immature stages of the rocky mountain wood tick, dermacentor andersoni. | | 1976 | 1263215 |
| the ecology of colorado tick fever in rocky mountain national park in 1974. iii. habitats supporting the virus. | ecologic studies of small mammals in rocky mountain national park (rmnp) were conducted in 1974 in order to identify the specific habitats within the lower montane forest that support colorado tick fever (ctf) virus. data was collected on the abundance and distribution of 4 primary rodent species, tick infestation, ctf virus, and neutralizing antibody prevalence. rodents were captured along transects crossing different habitats. open stands of ponderosa pine and shrubs on dry, rocky surfaces wer ... | 1989 | 2537045 |
| ecology of colorado tick fever. | | 1988 | 2849373 |
| co-circulation of multiple colorado tick fever virus genotypes. | colorado tick fever (ctf) virus, family reoviridae, genus orbivirus, contains 12 genes distinguishable by polyacrylamide gel electrophoresis (page). multiple genotypes of ctf virus were isolated at 3 field sites in colorado in 1985. five genotypes were found at campos cabin, 2 at drake, and 6 at rocky mountain national park. virus isolations were made in 1985 from 6 patients with ctf. these isolates were distinct from each other and the field isolates. although the ctf isolates were different by ... | 1989 | 2916731 |
| an overview of colorado tick fever. | certain features of colorado tick fever (ctf) virus and the disease it causes may be relevant to studies on bluetongue virus (btv), or other orbiviruses. rapid and easy detection of viral antigen in infected tissues and peripheral blood cells by immunofluorescence staining facilitate diagnosis of the disease. the prolonged (3-4 months) viremia is due to persistent intracellular infection, particularly of erythrocytes, in which the virus is protected from antibody or other host defense mechanisms ... | 1985 | 2989888 |
| diagnosis of colorado tick fever virus infection by enzyme immunoassays for immunoglobulin m and g antibodies. | an immunoglobulin m (igm) capture enzyme immunoassay technique was adapted for the detection of antibody to colorado tick fever virus in sera from 84 individuals for whom diagnosis had been confirmed by virus isolation or neutralization test. titers were compared with those for igg and neutralizing antibodies in these colorado tick fever cases. igm antibody titers were higher than neutralizing antibody titers, but neither appeared until 1 to 2 weeks after the onset of illness. neutralizing antib ... | 1985 | 2991332 |
| genetic relatedness of colorado tick fever virus isolates by rna-rna blot hybridization. | the sequence relatedness of ten isolates of the colorado tick fever (ctf) serogroup of orbiviruses was examined by rna-rna blot hybridization. the 12 dsrna genome segments of each of the isolates were electrophoresed in a 10% polyacrylamide gel, the segments were transferred electrophoretically to membranes and hybridized to radiolabelled genomic rna from ctf florio mouse-adapted strain (ctf fma) or ctf ss-18. all genome segments of the ten ctf viruses exhibited cross-hybridization signals with ... | 1987 | 3572358 |
| antigenic variants of colorado tick fever virus. | twenty strains of colorado tick fever (ctf) virus, isolated from ticks, mammals and humans, and two antigenic relatives of ctf virus were compared in cross-neutralization tests. viruses were tested using single-inoculation sera prepared in hamsters. antigenic variation, as measured by differences detected in the neutralization test, was noted among the virus isolates identified as strains of ctf virus. the virus strains isolated from humans appeared to vary the most in serological reactions. the ... | 1987 | 3572369 |
| [agglutination reaction of antibody-sensitized erythrocytes with colorado tick fever virus]. | | 1974 | 4141178 |
| colorado tick fever virus in cell culture. ii. physical and chemical properties. | trent, dennis w. (university of oklahoma school of medicine, oklahoma city), and l. vernon scott. colorado tick fever virus in cell culture. ii. physical and chemical properties. j. bacteriol. 91:1282-1288. 1966.-heat-inactivation kinetics for colorado tick fever (ctf) virus grown in l cells indicated that more than one rate constant was involved for inactivation at each exposure temperature. an arrhenius plot of the data indicated the inactivation rate constants to be dependent on the absolute ... | 1966 | 4286449 |
| induction of interferon in l cells by reoviruses. | l cell cultures challenged with reoviruses types 1 and 3 produced little to no detectable interferon under conditions which permitted virus replication and under conditions which prevented replication of a temperature-sensitive mutant strain of reovirus type 3 (ts-1). ultraviolet-irradiated reoviruses and double-stranded ribonucleic acids extracted from purified reovirus type 3 also induced little to no interferon in l cell cultures. under similar conditions, mm virus proved to be an effective i ... | 1973 | 4357988 |
| intra-erythrocytic location of colorado tick fever virus. | | 1972 | 4564691 |
| persistence of colorado tick fever virus in red blood cells. | | 1974 | 4823801 |
| colorado tick fever virus: an electron microscopic study. | | 1968 | 4871004 |
| evidence for the double-stranded nature of the rna of colorado tick fever virus, an ungrouped arbovirus. | | 1970 | 4988272 |
| interferon induction by colorado tick fever virus: a double-stranded rna virus. | | 1972 | 5007447 |
| contributions to the ecology of colorado tick fever virus. | | 1970 | 5425684 |
| occurrence of colorado tick fever virus in dermacentor andersoni ticks in british columbia. | | 1968 | 5667781 |
| electron microscopic observations of colorado tick fever virus in bhk 21 and kb cells. | | 1968 | 5698686 |
| colorado tick fever virus: growth in a mosquito cell line. | two strains of colorado tick fever virus grew in singh's aedes albopictus cells. in one of three experiments, virus growth continued for 7 weeks. | 1969 | 5798247 |
| collection of dermacentor andersoni (stiles) with carbon dioxide and its application in studies of colorado tick fever virus. | | 1965 | 5841585 |
| experimental colorado tick fever virus infection in colorado mammals. | one hundred and twenty-four small mammals of six species were inoculated with three strains of colorado tick fever (ctf) virus to define viremia and neutralizing (n) antibody responses. adult eutamias minimus and eutamias embrinus, and juvenile peromyscus maniculatus and spermophilus lateralis, were highly susceptible to development of viremic infection. adult s. lateralis and p. maniculatus were moderately susceptible (greater than or equal to 50% viremic). five sylvilagus nuttalli did not beco ... | 1981 | 6259958 |
| the ecology of colorado tick fever in rocky mountain national park in 1974. ii. infection in small mammals. | field studies of colorado tick fever (ctf) in small mammals in rocky mountain national park (rmnp) in 1974 established that eutamias minimus and spermophilus lateralis were the most important hosts for ctf virus and were the source of virus for immature stages of the tick vector, dermacentor andersoni. other species (peromyscus maniculatus, spermophilus richardsonii, eutamias umbrinus) are secondary hosts. the intensity of viral activity in rodents varied greatly from locality to locality. highe ... | 1981 | 6263122 |
| inhibition of bluetongue and colorado tick fever orbiviruses by selected antiviral substances. | the effects of four ribonucleic acid virus inhibitors were evaluated in cell cultures and in mice to determine inhibitory effects against bluetongue virus and colorado tick fever virus (ctfv). test compounds included 1-beta-d-ribofuranosyl-1,2,4-triazole-3-carboxamide (ribavirin), 3-deazaguanine, 3-deazauridine, and 9-(s)-(2,3-dihydroxypropyl)adenine. ribavirin-2',3',5'-triacetate (ribavirin triacetate) was evaluated in vivo against ctfv. inhibition of cytopathic effect and plaque reduction were ... | 1981 | 6282197 |
| isolation of eyach virus (reoviridae, colorado tick fever group) from ixodes ricinus and i. ventalloi ticks in france. | during the spring of 1981, two strains of an identical virus were isolated in mayenne, france, from ixodes ricinus l. and ixodes ventalloi gil collado, parasiting a wild rabbit (oryctolagus cuniculus l.). virological and serological results indicated that these strains belong to the colorado tick fever serogroup and are indistinguishable from eyach virus, a tick-borne virus previously described from west germany. study of dsrna page profiles confirmed these conclusions. the morphology and morpho ... | 1984 | 6508529 |
| seasonal activity and colorado tick fever virus infection rates in rocky mountain wood ticks, dermacentor andersoni (acari: ixodidae), in north-central colorado, usa. | | 1983 | 6827573 |
| survey for evidence of colorado tick fever virus outside of the known endemic area in california. | a virus very similar or identical to colorado tick fever (ctf) virus was recovered from the blood clot of one of 104 black-tailed jack rabbits (lepus californicus) examined during a survey for various zoonotic agents in mammals and ticks from the university of california, hopland field station, mendocino county, california, 1974--79. this is the first reported isolation of a ctf-like virus from l. californicus, and only the second time such a virus has been found in northwestern california. mend ... | 1982 | 7102919 |
| genome of colorado tick fever virus. | | 1981 | 7245618 |
| colorado tick fever in a resident of new york city. | when a traveler returns from abroad with a febrile illness, clinicians appropriately concern themselves with a potentially vast array of diagnostic exotica. the patient we describe herein did not leave the united states but nevertheless posed the same clinical dilemma after returning home to new york city from the western united states. this case of colorado tick fever, acquired on the utah-colorado border and first expressed in manhattan, serves as a useful reminder of the importance of taking ... | 1994 | 7952262 |
| ecology of porcupines (erethizon dorsatum) and colorado tick fever virus in rocky mountain national park, 1975-1977. | the involvement of porcupines, erethizon dorsatum (l.), in the ecology of colorado tick fever (ctf) virus in rocky mountain national park was investigated from 1975 to 1977. porcupine dens and feeding activity were found mostly on rocky knolls or on south-facing slopes within open stands of the montane coniferous forest, and 20 adult porcupines were trapped or captured by hand at those locations. an average of 24.6 +/- 5.4 adult dermacentor andersoni stiles ticks were found per animal (annual ra ... | 1993 | 8433332 |
| replication of colorado tick fever virus within human hematopoietic progenitor cells. | significant neutropenia, as well as thrombocytopenia and a mild anemia, occurs in patients infected with colorado tick fever virus. in this study, human bone marrow cd34+ cells and kg-1a cells, a human hematopoietic progenitor cell line, were infected in vitro with colorado tick fever virus. the time course and morphological appearance of viral replication in human progenitor cells were similar to those seen in erythroblasts and in hel cells and suggest one possible mechanism for the clinical he ... | 1993 | 8445735 |
| detection of colorado tick fever virus by using reverse transcriptase pcr and application of the technique in laboratory diagnosis. | colorado tick fever (ctf) virus elicits an acute illness in humans, producing nonspecific flu-like symptoms and a biphasic fever in approximately 50% of patients. the disease is transmitted by the adult rocky mountain wood tick (dermacentor andersoni), and therefore incidence is limited by the habitat and life cycle of that vector. the early symptoms of infection are difficult to distinguish from those of several other agents, especially rickettsia rickettsii. serologic testing is usually unable ... | 1997 | 9114408 |
| complete nucleotide sequence of colorado tick fever virus segments m6, s1 and s2. | the nucleotide sequences of the tenth (m6), eleventh (s1) and twelfth (s2) dsrna genomic segments of the florio strain (n-7180) of colorado tick fever virus were determined and found to be 675, 998 and 1884 bp, respectively, in length. a nonanucleotide motif and a hexanucleotide motif were found to be highly conserved in the 5' and 3' non-coding regions (ncrs), respectively, of the three segments. the first and last three nucleotides of each segment were of inverted complementarity, and segment- ... | 1997 | 9367376 |
| comparative sequence analysis of american, european and asian isolates of viruses in the genus coltivirus. | in this study, the basis for the classification of virus isolates grouped within the genus coltivirus, family reoviridae, is discussed. sequences of dsrna segments from american (segments 9-12), european (segment 12) and asian (segments 7-12) isolates were characterized and polythetic criteria were defined for their taxonomic classification. these criteria (including sequence analysis) permitted the different species to be distinguished and classified into two groups. in both groups, subgroups w ... | 1998 | 9780055 |
| serologic and molecular diagnosis of colorado tick fever viral infections. | molecular and serologic methods usable for the biological diagnosis of coltivirus infection are reported. we designed a multiplex reverse transcription-polymerase chain reaction system that allowed the simultaneous and specific amplification of three genomic segments from as little as 0.01 plaque-forming units. another system in the s2 viral segment permitted the differential diagnosis of american and european viral isolates. we also discuss some improvements of previous elisas, and the results ... | 1998 | 9840594 |
| complete sequence determination and genetic analysis of banna virus and kadipiro virus: proposal for assignment to a new genus (seadornavirus) within the family reoviridae. | arboviruses with genomes composed of 12 segments of double-stranded (ds) rna have previously been classified as members or probable members of the genus coltivirus within the family reoviridae: a number of these viruses have been isolated in north america and europe and are serologically and genetically related to colorado tick fever virus, the coltivirus type species. these isolates constitute subgroup a of the coltiviruses. the complete genome sequences are now presented of two asian arbovirus ... | 2000 | 10811934 |
| sequence determination and analysis of the full-length genome of colorado tick fever virus, the type species of genus coltivirus (family reoviridae). | the colorado tick fever virus (ctfv) is the type species of genus coltivirus, family reoviridae. its genome consisting of 12 segments of dsrna was completely sequenced. it was found to be 29,174 nucleotides long (the longest of all reoviridae genomes characterized to date). conserved sequences at the 5' end (sacuuuugy) and at the 3' end (wugcagus) of the 12 segments were identified. the analysis of the putative proteins deduced from the nucleotide sequences permitted to identify functional motif ... | 2000 | 10891382 |
| serologic survey for selected infectious disease agents in swift and kit foxes from the western united states. | a serologic survey of swift fox (vulpes velox) and kit fox (v. macrotis) from the western usa was conducted for 12 infectious diseases. samples from swift fox were collected between 1987 and 1992 from colorado (n = 44), kansas (n = 10), and wyoming (n = 9). samples from kit fox were collected in california (n = 86), new mexico (n = 18), utah (n = 9), and arizona (n = 6). overall antibody prevalence rates were 33 of 110 (30%) for canine parvovirus (cpv), 9 of 72 (13%) for canine distemper virus ( ... | 2000 | 11085448 |
| genus coltivirus (family reoviridae): genomic and morphologic characterization of old world and new world viruses. | we report a genomic and morphologic study of the european eyach (eya) virus (genus coltivirus, family reoviridae) and a comparative analysis with the american colorado tick fever (ctf) virus (the type species of the genus). the previously established, but distant, antigenic relationship between these viruses was strengthened by genetic findings (presence of cognate genes, amino acid identity between 55 and 88%, similar conserved terminal motifs, suspected read-through phenomenon in segment 9 of ... | 2002 | 11958454 |
| colorado tick fever. | colorado tick fever, also known as mountain fever and mountain tick fever, is a well-described, viral, tick-borne disease common to the rocky mountain region of the united states and canada. the rocky mountain wood tick, dermacentor andersoni, is the primary vector. the triad of high fever, severe myalgia, and headache is typical, but not specific. although a self-limited disease in most cases, severe complications may occur. pcr techniques have been developed that allow the diagnosis to be esta ... | 2002 | 11982311 |
| nucleotide sequences of double-stranded rna segments from a hypovirulent strain of the white root rot fungus rosellinia necatrix: possibility of the first member of the reoviridae from fungus. | twelve double-stranded (ds) rna segments were detected from a hypovirulent strain w370 of the white root rot fungus rosellinia necatrix. the estimated molecular weights ranged from 0.41 x 10(6) to 2.95 x 10(6). full length cdna clones for eight segments were obtained. northern blot analysis suggested that each segment was genetically unique. the nucleotide sequences of eight full length dsrna segments were determined. one long open reading frame was found in each segment. conserved sequences at ... | 2002 | 12206302 |
| recombinant vp7-based enzyme-linked immunosorbent assay for detection of immunoglobulin g antibodies to colorado tick fever virus. | vp6, vp7, vp9, vp10, vp11, and vp12 of colorado tick fever virus (ctf virus), a virus member of the genus coltivirus, family reoviridae, were expressed in bacteria with the pgex-4t-2 vector. a partial sequence of vp7 (designated pvp7) was chosen to elaborate an enzyme-linked immunosorbent assay (elisa) for detecting anti-ctf virus immunoglobulin g (igg) antibodies in humans. this was based on two observations: (i) among all expressed proteins, pvp7 showed the highest immunoreactivity to an anti- ... | 2003 | 12734255 |
| viral meningitis and encephalitis: traditional and emerging viral agents. | in the united states, the annual number of central nervous system (cns) infections that occur as a result of viral agents far exceeds that of infections caused by bacteria, yeast, molds, and protozoa combined. the recent incursion of west nile virus (wnv) into north america has led to a dramatic change in the incidence and epidemiology of summer-associated viral cns disease. as a result of increased testing for wnv, lesser known viral causes of cns infection have been identified. even the epidem ... | 2003 | 12881794 |
| molecular characterization of dsrna segments 2 and 5 and electron microscopy of a novel reovirus from a hypovirulent isolate, w370, of the plant pathogen rosellinia necatrix. | a hypovirulent isolate, w370, of the white root rot fungus rosellinia necatrix has previously been shown to harbour 12 dsrna segments. in this study, complete nucleotide sequences of segments 2 and 5 of w370 dsrnas were determined. the nucleotide sequence of genome segment 2 was 3773 bases long with a single long open reading frame (orf) encoding 1226 amino acid residues with a predicted molecular mass of approximately 138.5 kda. the nucleotide sequence of segment 5 was 2089 bases long with a si ... | 2003 | 12917464 |
| isolation of colorado tick fever virus from rodents in colorado. | | 1958 | 13568801 |
| tissue culture studies with colorado tick fever virus. i. isolation and propagation of virus in kb cultures. | | 1958 | 13575867 |
| studies of the ecology of colorado tick fever virus in western montana. | | 1959 | 13626952 |
| development of colorado tick fever virus in the rocky mountain wood tick, dermacentor andersoni. | | 1959 | 13626953 |
| colorado tick fever. ii. the behavior of colorado tick fever virus in rodents. | | 1960 | 13688985 |
| experimental infection of rhesus monkeys with colorado tick fever virus. | | 1959 | 13827524 |
| natural history of colorado tick fever virus. | | 1962 | 13889747 |
| plaque assay procedure for colorado tick fever virus. | deig, e. frank (university of california, berkeley), and h. m. s. watkins. plaque assay procedure for colorado tick fever virus. j. bacteriol. 88:42-47. 1964.-a reproducible plaque assay procedure is described for the quantitation of colorado tick fever virus in a cell line established from embryonic hamster tissue. under the best conditions, plaques approximately 4 mm in diameter were formed after incubation at 37 c of 4 to 6 days. several environmental variables in the procedure were studied. ... | 1964 | 14197903 |
| colorado tick fever virus in cell culture. i. cell-type susceptibility and interaction with l cells. | trent, dennis w. (university of oklahoma school of medicine, oklahoma city) and l. vernon scott. colorado tick fever virus in cell culture. i. cell-type susceptibility and interaction with l cells. j. bacteriol. 88:702-708. 1964.-colorado tick fever (ctf) virus was serially propagated in monolayer cultures of l and fl cells. early passages of virus in fl cells yielded viral titers 10(4)-fold greater than did the corresponding l-cell passages. during l-cell passage number 4, there was a 10(3)-fol ... | 1964 | 14208510 |
| [eyach virus: relative of the colorado tick fever virus rediscovered in baden-württemberg]. | | 2003 | 14518442 |
| a reovirus of the fungus cryphonectria parasitica that is infectious as particles and related to the coltivirus genus of animal pathogens. | rna viruses of filamentous fungi fall into two broad categories, those that contain double-stranded rna (dsrna) genomes in rigid particles and those that are more closely related to positive-sense, single-stranded rna viruses with dsrna replicative intermediates found within lipid vesicles. effective infectivity systems have been described for the latter, using rna transcripts, but not for the former. we report the characterization of a reovirus from cryphonectria parasitica, the filamentous fun ... | 2004 | 14694120 |
| complete nucleotide sequences of genome segments 1 and 3 of rosellinia anti-rot virus in the family reoviridae. | the nucleotide sequences of genome segments 1 and 3 of rosellinia anti-rot virus (rarv) from a hypovirulent isolate, w370, of the plant pathogen rosellinia necatrix were determined. the complete nucleotide sequence of the genome segment 1 encoded a putative rna-dependent rna polymerase (rdrp). the deduced amino acid sequence of rdrp of rarv showed 29% identity with rdrps of colorado tick fever virus (ctfv) and european eyach virus (eyav) in the genus coltivirus, and identities of 23-21% with mem ... | 2004 | 15045563 |
| recombinant vp6-based enzyme-linked immunosorbent assay for detection of immunoglobulin g antibodies to eyach virus (genus coltivirus). | eyach virus (eyav) is a tick-borne virus belonging to genus coltivirus, family reoviridae. it was isolated in germany and france and has been suspected to be responsible for neurological diseases in humans. to date, there has been no relatively rapid and relatively specific serological assay for eyav. | 2004 | 15135744 |
| termination and read-through proteins encoded by genome segment 9 of colorado tick fever virus. | genome segment 9 (seg-9) of colorado tick fever virus (ctfv) is 1884 bp long and contains a large open reading frame (orf; 1845 nt in length overall), although a single in-frame stop codon (at nt 1052-1054) reduces the orf coding capacity by approximately 40 %. however, analyses of highly conserved rna sequences in the vicinity of the stop codon indicate that it belongs to a class of 'leaky terminators'. the third nucleotide positions in codons situated both before and after the stop codon, show ... | 2004 | 15269364 |
| response of man to egg-adapted colorado tick fever virus. | | 1950 | 15430410 |
| complete genome sequence of mycoreovirus-1/cp9b21, a member of a novel genus within the family reoviridae, isolated from the chestnut blight fungus cryphonectria parasitica. | mycoreovirus 1 (myrv-1) is the type species of the newly described genus mycoreovirus of the large virus family reoviridae. the virus was isolated from a hypovirulent strain (9b21) of the chestnut blight fungus, cryphonectria parasitica. a previous study showed that double-shelled particles introduced to fungal spheroplasts resulted in stably infected colonies. of the 11 double-stranded rna genomic segments (s1-s11), the three largest (s1-s3) were sequenced previously and shown to have moderate ... | 2004 | 15483262 |
| transfusion-transmitted tick-borne infections: a cornucopia of threats. | over the past several decades, the frequency of contact between humans and ticks has increased dramatically. concomitantly, several newly recognized tick-borne pathogens have emerged joining those already known to be transmitted by ticks. together these factors have led to an enhanced public health awareness of ticks, tick-borne agents, and their associated diseases. reports that several of these agents are transmitted by blood transfusion have raised concerns about blood safety. the primary age ... | 2004 | 15497129 |
| coltiviruses and seadornaviruses in north america, europe, and asia. | coltiviruses are tickborne viruses of the genus coltivirus. the type species, colorado tick fever virus (from north america), has been isolated from patients with flulike syndromes, meningitis, encephalitis, and other severe complications. another coltivirus, eyach virus, has been isolated from ticks in france and germany and incriminated in febrile illnesses and neurologic syndromes. seadornaviruses are endemic in southeast asia, particularly indonesia and china. the prototype virus of the genu ... | 2005 | 16318717 |
| detection of colorado tick fever viral rna in acute human serum samples by a quantitative real-time rt-pcr assay. | a quantitative real-time rt-pcr assay for the detection of colorado tick fever (ctf) viral rna in human clinical samples is presented. the sensitivity of this assay has been shown to be greater than that of the isolation of virus in vero cells by standard plaque assay in a direct comparison. the specificity of the ctf quantitative real-time rt-pcr assay was determined by the exclusive detection of ctf viral rnas when applied to a diverse panel of ctf viral isolates and reference strain agents kn ... | 2007 | 17126919 |
| powassan encephalitis and colorado tick fever. | this article discusses two tick-borne illnesses: powassan encephalitis, a rare cause of central nervous system infection caused by the powassan virus, and colorado tick fever, an acute febrile illness caused by the colorado tick fever virus common to the rocky mountain region of north america. | 2008 | 18755390 |
| colorado tick fever; studies on mouse brain adapted virus. | | 1947 | 20268418 |
| colorado tick fever studies on chick embryo adapted virus. | | 1947 | 20268419 |
| adaptation of colorado tick fever virus to mouse and developing chick embryo. | | 1946 | 20993212 |
| characterization of the stop codon readthrough signal of colorado tick fever virus segment 9 rna. | termination codon readthrough is utilized as a mechanism of expression of a growing number of viral and cellular proteins, but in many cases the mrna signals that promote readthrough are poorly characterized. here, we investigated the readthrough signal of colorado tick fever virus (ctfv) segment 9 rna (seg-9). ctfv is the type-species of the genus coltivirus within the family reoviridae and is a tick-borne, double-stranded, segmented rna virus. seg-9 encodes a 36-kda protein vp9, and by readthr ... | 2011 | 22190746 |
| infection with colorado tick fever virus among humans and ticks in a national park and forest, wyoming, 2010. | colorado tick fever (ctf) is an underreported tick-borne viral disease occurring in the western united states. ctf illness includes fever, headache, and severe myalgia lasting for weeks. wyoming has one of the highest ctf incidence rates with approximately 30% of infected persons reporting tick exposure in a wyoming national park or forest before symptom onset. we assessed ctf virus infections among humans and dermacentor andersoni ticks in grand teton national park (grte) and bridger-teton nati ... | 2014 | 25229706 |
| colorado tick fever in the united states, 2002-2012. | colorado tick fever (ctf) is an acute systemic febrile illness caused by the ctf virus (ctfv). the last national summary of ctf cases in the united states included cases reported through 2001. this study summarizes national surveillance data for ctf from 2002 through 2012 and examines trends in the epidemiology and testing of identified ctf cases. | 2015 | 25988440 |