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nocardia pseudobrasiliensis sp. nov., a new species of nocardia which groups bacterial strains previously identified as nocardia brasiliensis and associated with invasive diseases.we studied five strains of a new nocardia taxon recently identified among nocardia brasiliensis strains associated with invasive diseases (r. j. wallace, jr., b. a. brown, z. blacklock, r. ulrich, k. jost, j. m. brown, m. m. mcneil, g. onyi, v. a. steingrube, and j. gibson, j. clin. microbiol. 33:1528-1533, 1995) to determine their taxonomic status. several characteristics of these organisms, including the presence of chemotype iv cell walls, nocardomycolic acids, a predominant menaquinone simil ...19968573505
activities of the glycylcyclines n,n-dimethylglycylamido-minocycline and n,n-dimethylglycylamido-6-demethyl-6-deoxytetracycline against nocardia spp. and tetracycline-resistant isolates of rapidly growing mycobacteria.susceptibilities to the new semisynthetic tetracycline (tet) compounds n,n-dimethylglycylamido-minocycline (dmg-mino) and n,n-dimethylglycylamido-6-demethyl-6-deoxytetracycline (dmg-dmdot) were compared with those to doxycycline, minocycline, and tet for 198 tet-resistant (tetr) and 33 tet-susceptible (tets) clinical isolates of rapidly growing mycobacteria (rgm) including the mycobacterium fortuitum group, mycobacterium abscessus, mycobacterium chelonae, and mycobacterium mucogenicum and 68 iso ...19968849243
nocardicyclins a and b: new anthracycline antibiotics produced by nocardia pseudobrasiliensis.nocardicyclins a (1) and b (2), new anthracycline antibiotics have been isolated from the mycelial cake of nocardia pseudobrasiliensis ifm 0624 (jcm 9894). the molecular formulae of 1 and 2 have been determined as c30h35no11 and c32h37no12, respectively, and the structures were characterized by 1- and 8-methoxyl groups, a 10-carbonyl group and a novel carbon-methylated aminosugar constituent. nocardicyclin a (1) exerts cytotoxic activity against l1210 and p388 leukemia. nocardicyclins a (1) and ...19979402986
production of nocardicyclins by clinical isolates of nocardia pseudobrasiliensis and in vivo antitumor activity of the antibiotic. 19989711224
disseminated nocardia pseudobrasiliensis infection in a patient with aids in brazil. 199910028089
first human case of nocardiosis caused by nocardia pseudobrasiliensis in japan.nocardia sp. ifm 0896, an actinomycete with biochemical characteristics that differed from nocardia brasiliensis, was isolated from a 71-year-old japanese man with a history of tuberculosis and cancer. although the isolate was tentatively identified as n. brasiliensis, the morphological and physiological characteristics of strain ifm 0896 were different from those of n. brasiliensis ifm 0236t. the results of 16s rrna gene sequence phylogenies and pcr-rflp analysis of a heat shock protein reveale ...200212749583
nocardia inohanensis sp. nov., nocardia yamanashiensis sp. nov. and nocardia niigatensis sp. nov., isolated from clinical specimens.comparative 16s rdna studies on six strains of actinomycete isolated from clinical specimens revealed that they belong to the genus nocardia and are closely related to nocardia seriolae, nocardia otitidiscaviarum, nocardia uniformis, nocardia pseudobrasiliensis and nocardia crassostreae. however, the novel organisms consistently formed a clade distinct from that of the five latter species. determination of dna-dna relatedness indicated that these strains could be classified under three novel spe ...200415023976
nocardia mexicana sp. nov., a new pathogen isolated from human mycetomas.three isolates collected from human mycetomas and showing an unusual brownish purple pigmentation on bennett agar plates were analyzed by a polyphasic taxonomic approach, including morphological, biochemical, physiological, and chemotaxonomic properties coupled with genomic and phylogenetic analysis. it clearly appeared that these microorganisms were distinct from their closest phenotypic and genetic match, the most related species according to 16s rrna gene sequence analysis being nocardia pseu ...200415472305
nocardia jiangxiensis sp. nov. and nocardia miyunensis sp. nov., isolated from acidic soils.the taxonomic positions of two soil actinomycetes, strains 117(t) and 43401(t), provisionally assigned to the genus nocardia were determined in a polyphasic study. the organisms were found to have phenotypic properties typical of members of the genus nocardia, and formed a distinct branch in the nocardia 16s rrna gene tree. it was evident from the phylogenetic data that the isolates were most closely, albeit loosely, associated with the type strains of nocardia nova and nocardia pseudobrasiliens ...200516166688
[taxonomy and phylogenetic analysis of infectious nocardia strains isolated from clinical samples].following recent advances in medical technology, the increased number of immunocompromised patients such as those with organ transplants has led to an increase in opportunistic infections due to nocardia. although nocardiosis has been considered to be rare, recent reports indicate that the incidence of the infection is increasing. the nocardia asteroides group is the principal source of infectious species, but the definition of species in nocardia is problematic because species identification of ...200717502841
nocardia acidivorans sp. nov., isolated from soil of the island of stromboli.a gram-positive, non-spore-forming bacterium (strain gw4-1778(t)) was isolated from soil of the italian island of stromboli. 16s rrna gene sequence similarity studies showed that strain gw4-1778(t) is a member of the genus nocardia, most closely related to nocardia pseudobrasiliensis (genbank accession no. dq659914; 98.6 %), nocardia nova (z36930; 98.6 %), nocardia niigatensis (ab092563; 98.4 %), nocardia jiangxiensis (ay639902; 98.0 %), nocardia uniformis (z46752; 98.0 %) and nocardia miyunensi ...200717551026
ventriculitis and choroid plexitis caused by multidrug-resistant nocardia pseudobrasiliensis.we describe a case of ventriculitis and choroid plexitis caused by a multidrug-resistant nocardia pseudobrasiliensis in an immunocompetent child. difficulties establishing an etiologic diagnosis, inconsistencies of antibiotic susceptibility testing, and the side effects of various antimicrobials presented challenges to her treatment and eventual favorable outcome.200818520971
nocardithiocin, a novel thiopeptide antibiotic, produced by pathogenic nocardia pseudobrasiliensis ifm 0757.nocardithiocin is a novel thiopeptide compound produced by the pathogenic nocardia pseudobrasiliensis strain ifm 0757. it shows a strong activity against acid-fast bacilli such as the mycobacterium and gordonia species. nocardithiocin was highly active against rifampicin-resistant as well as -sensitive mycobacterium tuberculosis strains, and most of the resistant strains were inhibited at concentrations ranging from 0.025 to 1.56 microg ml(-1). the structure of the thiopeptide antibiotic contain ...200919745839
nocardia pseudobrasiliensis as an emerging cause of opportunistic infection after allogeneic hematopoietic stem cell transplantation.we report the case of a 55-year-old man who exhibited a nodular pneumonia 4 months after an allogeneic hematopoietic stem cell transplantation. culture of the bronchoalveolar lavage fluid revealed nocardia pseudobrasiliensis. this recently described carbapenem-resistant species should be included in the differential diagnosis of fungal infection in this setting.201019940053
identification and functional analysis of the nocardithiocin gene cluster in nocardia pseudobrasiliensis.nocardithiocin is a thiopeptide compound isolated from the opportunistic pathogen nocardia pseudobrasiliensis. it shows a strong activity against acid-fast bacteria and is also active against rifampicin-resistant mycobacterium tuberculosis. here, we report the identification of the nocardithiocin gene cluster in n. pseudobrasiliensis ifm 0761 based on conserved thiopeptide biosynthesis gene sequence and the whole genome sequence. the predicted gene cluster was confirmed by gene disruption and co ...201526588225
the first korean case of disseminated mycetoma caused by nocardia pseudobrasiliensis in a patient on long-term corticosteroid therapy for the treatment of microscopic polyangiitis.nocardia pseudobrasiliensis is predominantly associated with invasive infections in immunocompromised patients. we report a case of disseminated mycetoma caused by n. pseudobrasiliensis in a 57-yr-old woman with microscopic polyangiitis, who was treated for 3 months with corticosteroids. the same organism was isolated from mycetoma cultures on the patient's scalp, right arm, and right leg. the phenotypic characteristics of the isolate were consistent with both nocardia brasiliensis and n. pseudo ...201323667849
nocardia rayongensis sp. nov., isolated from thai peat swamp forest soil.an actinomycete strain, ry45-3t, isolated from a peat swamp forest soil in rayong province, thailand, was characterized using a polyphasic approach. the strain belonged to the genus nocardia on the basis of morphological, physiological, biochemical and chemotaxonomic properties. cell-wall peptidoglycan contained meso-diaminopimelic acid. the n-acyl group of muramic acid in the cell wall was glycolyl type. the diagnostic sugars in whole-cell hydrolysates were galactose and arabinose. mk-8 (h4ω-cy ...201626873179
multidrug-resistant nocardia pseudobrasiliensis presenting as multiple muscle abscesses.a 79-year-old caucasian man presented with multiple leg abscesses due to nocardia pseudobrasiliensis. he was on chronic steroid therapy for myasthenia gravis. we present the difficulties in diagnosis and treatment of this rare organism. n. pseudobrasiliensis is a new emerging species that was previously thought to belong to the n. brasiliensis species. the distinction between the two species is extremely important given the different antibiotic susceptibility pattern and association of n. pseudo ...201525948839
vertebral osteomyelitis and multiple cutaneous lesions in a dog caused by nocardia pseudobrasiliensis. 201725103815
susceptibility profiles of nocardia isolates based on current taxonomy.the genus nocardia has undergone rapid taxonomic expansion in recent years, and an increasing number of species are recognized as human pathogens. many established species have predictable antimicrobial susceptibility profiles, but sufficient information is often not available for recently described organisms. additionally, the effectiveness of sulfonamides as first-line drugs for nocardia has recently been questioned. this led us to review antimicrobial susceptibility patterns for a large numbe ...201424247124
[nocardia pseudobrasiliensis pneumonia in a heart transplant recipient]. 201323465630
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