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infection of wild and laboratory animals with machupo and latino viruses.natural infection with machupo and latino viruses occurs only in the cricetine rodent calomys callosus. machupo virus induces fatal infection in suckling mice and hamsters, and in adult guinea-pigs, marmosets, and rhesus monkeys. latino virus kills only suckling hamsters; it produces chronic but non-viraemic infection in calomys rodents.machupo virus, in contrast, induces a viraemic immunotolerant infection in suckling calomys, and a split response in animals more than 9 days of age. tolerant in ...1975182399
arenoviruses in vero cells: ultrastructural studies.thin-section electron microscopy was carried out on vero green monkey kidney cell cultures infected with some viruses of the newly constituted arenovirus group. junin, machupo, amapari, pichinde, parana, tamiami, and latino viruses were morphologically identical and indistinguishable from lymphocytic choriomeningitis virus, the prototype virus of the group. virus particles were round, oval, or pleomorphic, 60 to 280 nm in diameter, and matured via budding from plasma membranes. most characterist ...19705497898
new world arenavirus clade c, but not clade a and b viruses, utilizes alpha-dystroglycan as its major receptor.alpha-dystroglycan (alpha-dg) has been identified as a major receptor for lymphocytic choriomeningitis virus (lcmv) and lassa virus, two old world arenaviruses. the situation with new world arenaviruses is less clear: previous studies demonstrated that oliveros virus also exhibited high-affinity binding to alpha-dg but that guanarito virus did not. to extend these initial studies, several additional old and new world arenaviruses were screened for entry into mouse embryonic stem cells possessing ...200211967329
detection of latino virus (arenaviridae: mammarenavirus) naturally infecting calomys callidus.mammarenavirus species are associated with a specific rodent host species, although an increasing number of virus has been associated to more than one host, suggesting that co-evolution is less robust than initially thought. there are few eco-epidemiological studies of south america mammarenaviruses in non-endemic areas of arenavirus hemorrhagic fever, affecting specially our current knowledge about animal reservoirs and virus range and host-virus relations. in brazil, seven arenavirus species w ...201729217383
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