Publications

TitleAbstractYear
Filter
PMID
Filter
viability of fungal cultures maintained at -70 degrees c.one thousand four hundred forty-seven clinical and environmental isolates of molds, yeasts, aerobic actinomycetes, and algae belonging to 164 genera (382 taxa) maintained on potato dextrose agar at -70 degrees c for periods ranging from 6 months to 13 years were subcultured and then incubated at 25 degrees c to determine their viabilities. thirty-three isolates, alternaria alternata (n = 1), apophysomyces elegans (n = 1), bipolaris spicifera (n = 1), blastomyces dermatitidis (n = 4), cokeromyces ...19921572955
phaeohyphomycosis caused by exserohilum rostratum mimicking hemorrhagic herpes zoster. 19911802911
phaeohyphomycosis of the eye caused by exserohilum rostratum in india.a 40-year-old woman developed a corneal ulcer with hypopyon following a traumatic episode. in a koh mount dematiaceous, septate, branched hyphae were demonstrated, and heavy growth of exserohilum rostratum was obtained in culture. no bacterial pathogens were isolated. the patient was treated with natamycin and subsequently with ketoconazole. in spite of antimycotic therapy a descemetocele of the eye remained. this observation represents the first documented case of an exserohilum infection in in ...19911824419
multiple intracranial mucoceles associated with phaeohyphomycosis of the paranasal sinuses.the purpose of this article is to alert clinicians to a new pathogenic fungus of the paranasal sinuses called exserohilum rostratum. exserohilum species are one of the etiologic agents of phaeohyphomycosis, a constellation of entities caused by dematiaceous fungi. this class of fungal sinus infection has emerged only in the past decade; it occurs primarily in immunocompetent individuals and produces a tenacious, progressive pansinusitis. to our knowledge, this study describes the first case of m ...19902206510
human exserohilum and bipolaris infections: report of exserohilum nasal infection in a neutropenic patient with acute leukemia and review of the literature.a neutropenic patient with acute myeloid leukemia developed nasal and perinasal infection caused by the fungus exserohilum rostratum. early amphotericin b treatment along with marrow recovery resulted in resolution of the infection. a review of other previously reported cases of exserohilum and bipolaris infections show a favourable outcome in most patients who receive systemic antifungal treatment with amphotericin b.19873312557
primary cutaneous phaeohyphomycosis due to exserohilum rostratum (drechslera rostrata) in a child with leukemia. 19863460042
subcutaneous phaeohyphomycosis caused by exserohilum rostratum in an immunocompetent host.a healthy, 55-year-old woman developed a subcutaneous abscess and systemic symptoms of nausea, dizziness, and chills following minor trauma to her leg. histopathologic examination of a skin biopsy specimen revealed golden-brown colored mycelial elements, and culture resulted in growth of a dematiaceous fungus identified as exserohilum rostratum. surgical excision of the abscess and concomitant oral therapy with ketoconazole resulted in resolution of symptoms. in previously reported cases of huma ...19873662567
fatal disseminated infection due to exserohilum rostratum in a patient with aplastic anemia: case report and review.exserohilum rostratum is a dematiaceous fungus that rarely causes infection in humans. we describe a patient with severe aplastic anemia who developed fatal disseminated disease caused by e. rostratum, and we review the english-language literature on this unusual agent. our patient initially presented with signs and symptoms of sinusitis, which progressed to invasive pulmonary disease. the clinical course and histopathologic findings at autopsy were similar to those seen in cases of invasive asp ...19957727648
new sources of cytochalasins a and b from dematiaceous hyphomycetes.one hundred isolates of 27 species belonging to 13 genera of dematiaceous hyphomycetes were screened for production of cytochalasins a and b. most of these isolates (94) were obtained from assiut university culture collection, botany department, faculty of science, assiut university, egypt; three isolates from cbs, the netherlands; two isolates from dsm, germany; and one isolate from imi, uk. the results revealed that 10 isolates of six species representing five genera of fungi produced cytochal ...19947765218
mixed cutaneous phaeohyphomycosis in a cocaine user.the dematiaceous fungi rarely cause serious disease in humans. we report a case of mixed cutaneous phaeohyphomycosis caused by two dematiaceous fungi, exserohilum rostratum and curvularia species, and review the microbiological characteristics and clinical significance of these organisms.19938353230
cutaneous and subcutaneous phaeohyphomycosis caused by exserohilum rostratum.phaeohyphomycosis of the skin caused by exserohilum is rare. four cases have been reported; all were subcutaneous in type and all were caused by exserohilum rostratum. we report two types of skin infection, cutaneous and subcutaneous, that were caused by e. rostratum in two immunocompromised men. pleomorphic fungal elements were noted within the dermal suppurative and granulomatous infiltrate in case 1 and only within the central hyperkeratotic horny layer of a porokeratosis-like lesion in case ...19938436654
a case of cutaneous phaeohyphomycosis caused by exserohilum rostratum, its in vitro sensitivity and review of literature.a 40 year old woman presented with the infection of skin of 3 years duration on the upper anterior aspect of fore-arm. histologic examination of the skin tissue revealed dematiaceous hyphae, aggregated structures or single celled elements. on detailed mycological examination the isolate was identified as exserohilum rostratum. among the antimycotic tested in vitro amorolfine was found to be most effective with mic value of 3 mcg/ml. this is the first report of e. rostratum infection of man from ...19958532051
corneal phaeohyphomycosis due to exserohilum rostratum. a case report and brief review.we report a rare case of corneal phaeohyphomycosis due to exserohilum rostratum following organic trauma. a known cause of cutaneous and subcutaneous phaeohyphomycosis, this fungus has been very rarely associated with infections of the eye. being a plant pathogen, along with other saprophytic dematiaceous fungi the possible role in keratomycosis is discussed.19968739691
exserohilum rostratum causing keratitis in india.a case of mycotic keratitis due to atypical exserohilum rostratum is reported in a 42-year-old male with hansens disease.199910361269
prevalence of allergic sensitization to regional inhalants among allergic patients in jakarta, indonesia.sensitization towards a panel of eight regional inhalant allergens was evaluated among 107 patients with allergic rhinitis and/or asthma. a total of 32 children (age 5-13 years, mean 9 years; 18 male, 14 female), 75 adolescents and adults (aged 14-66 years, mean 32 years; 21 male, 54 female) and 20 normal control volunteers (aged 16-46, mean 30 years; 4 male, 16 female) were evaluated via skin prick test. a weal response of 3 x 3 mm or greater was taken to be positive. the sensitization rates am ...199910403003
allergen detection from 11 fungal species before and after germination.allergens dispersed by airborne fungal spores play an important but poorly understood role in the underlying cause and exacerbation of asthma. previous studies suggest that spores of alternaria and aspergillus release greater quantities of allergen after germination than before germination. it is unknown whether this is true of other allergenic fungi.200312589346
isolation and structure assignments of rostratins a-d, cytotoxic disulfides produced by the marine-derived fungus exserohilum rostratum.four new cytotoxic disulfides, rostratins a-d (1-4), were isolated from the whole broth of the marine-derived fungus exserohilum rostratum (drechsler), a fungal strain found associated with a marine cyanobacterial mat. the structures of these cyclic dipeptides were established through chemical degradation and a variety of two-dimensional nmr techniques. the absolute configurations of the rostratins were determined by the modified mosher method. in the case of the polyhydroxylated compound 1 and ...200415332857
invasive exserohilum sinusitis in a patient with aplastic anemia.a case of acute, invasive, sinusitis caused by the dematiaceous mold exserohilum rostratum is presented. herein we examine the subtypes of fungal sinusitis and briefly discuss some characteristics, pathologic and microbiologic differential diagnoses and management strategies of exserohilum sinus infection in an immunocompromised patient.200516220103
ethmoidal sinusitis caused by exserohilum rostratum in a patient with malignant lymphoma after non-myeloablative allogeneic peripheral blood stem cell transplantation.we describe a patient with aggressive lymphoma who contracted an ethmoidal sinus infection due to exserohilum rostratum after non-myeloablative allogeneic peripheral blood stem cell transplantation. e. rostratum is an extremely rare causative pathogen of invasive fungal infection. phylogenetic tree analysis of the d1/d2 domains within the lsu rdna identified the molecular structure of isolates. we believe this is the first description of e. rostratum infection in a patient who underwent hematopo ...200717462000
keratomycosis due to exserohilum rostratum - a case report.we report here a case of keratomycosis by exserohilum rostratum. an 18-year old female patient presented with pain and watery discharge from the left eye since 10 days. clinically the case was diagnosed as keratomycosis. gram stain and koh preparation of corneal scrapings revealed fungal elements. fungal isolate was identified as exserohilum rostratum by standard techniques.200417642711
oxacyclododecindione, a novel inhibitor of il-4 signaling from exserohilum rostratum.in a screening program for new metabolites from fungi inhibiting the il-4 mediated signal transduction, a novel chlorinated macrocyclic lactone, designated as oxacyclododecindione, was isolated from fermentations of the imperfect fungus exserohilum rostratum. the structure was determined by a combination of spectroscopic techniques. oxacyclododecindione inhibits the il-4 induced expression of the reporter gene secreted alkaline phosphatase (seap) in transiently transfected hepg2 cells with ic50 ...200818653993
11-hydroxymonocerin from the plant endophytic fungus exserohilum rostratum.a new analogue of monocerin, 11-hydroxymonocerin (2), along with monocerin (1) and 12-hydroxymonocerin (3) were isolated from cultures of exserohilum rostratum, a fungal strain endophytic in stemona sp. the structure of 2 was determined by analysis of nmr and ms data and by comparison of spectroscopic data to those of 1. monocerin (1) and 11-hydroxymonocerin (2) displayed activity against plasmodium falciparum (k1, multidrug-resistant strain) with ic50 values of 0.68 and 7.70 microm, respectivel ...200818774863
hospital-acquired phaeohyphomycosis due to exserohilum rostratum in a child with leukemia.the present study describes a case of cutaneous phaeohyphomycosis caused by exserohilum rostratum in a child undergoing treatment for leukemia. the infection was possibly due to contaminated intravenous dressings and was successfully treated with surgical excision combined with liposomal amphotericin b. consequently, new infection control policies have been implemented at chu sainte-justine (montreal, quebec).200718923719
variation in occurrence of dematiaceous hyphomycetes on forage bermudagrass over years, sampling times, and locations.abstract leaf samples of forage bermudagrass with symptoms of infection by species of bipolaris, curvularia, and exserohilum (dematiaceous hyphomycetes) were collected from three swine waste application sites in mississippi at eight sampling times during each of 3 years. samples were assayed for pathogens by observing sporulation on plated leaf tissue. among 3,600 leaves assayed, eight species of the three genera were observed. features and criteria for the practical identification of species on ...200518943471
cutaneous phaeohyphomycosis caused by exserohilum rostratum in a patient with cutaneous t-cell lymphoma. 200919261021
deep cutaneous fungal infections in immunocompromised children.life-threatening infections from ubiquitous fungi are becoming more prevalent in adults and children because of the increased use of immunosuppressive agents and broad-spectrum anti-infective drugs. extremely low birth weight premature neonates and patients with a disrupted epidermal barrier are also at increased risk. lethality is high, particularly with delayed diagnosis. as cutaneous lesions are often the first manifestation of such infections, early recognition of suspicious lesions is cruci ...200919748155
decorospora, a new genus for the marine ascomycete pleospora gaudefroyi.in this paper, we investigate the phylogenetic placement of pleospora gaudefroyi using partial ssu as well as its ribosomal dna sequences. both ssu and its data sets agreed in the placement of p. gaudefroyi. parsimony and neighbor-joining analyses of each data set placed p. gaudefroyi within the pleosporaceae with 100% bootstrap support. pleospora gaudefroyi was sister taxon in the pleosporaceae represented by alternaria alternata, cochliobolus sativus, pleospora herbarum, pyrenophora tritici-re ...200221156538
in vitro and in vivo biocontrol of soil-borne phytopathogenic fungi by certain bioagents and their possible mode of action.the study aimed to investigate new wide-spectrum biological control agents against soil-borne fungal plant pathogens. screening of 336 fungal strains and 256 bacterial strains was carried out in vitro to select the most promising isolates for controlling destructive pathogens of greenhouse-vegetables. in dual cultures, bacillus subtilis jf419701 and trichoderma harzianum jf419706 (teleomorph: hypocrea lixii) inhibited the growth of alternaria alternata, fusarium oxysporum, exserohilum rostratum, ...201223269217
setosphaeria rostrata: insights from the sequenced genome of setosphaeria turcica.exserohilum rostratum, also known as setosphaeria rostrata caused an outbreak of meningitis in 2012. s. rostrata is known as a minor pathogen of grasses and a member of the dothideomycetes, a group that includes saprobes as well as mild to aggressive plant pathogens. a few taxa in this group, such as e. rostratum and cochliobolus lunatus (curvularia lunata) can be human pathogens, in favorable circumstances. fortunately, human disease caused by e. rostratum is rare. however, the increasing numbe ...201324012822
morphological and molecular characterization, sexual reproduction, and pathogenicity of setosphaeria rostrata isolates from rice leaf spot.setosphaeria rostrata, a common plant pathogen causing leaf spot disease, affects a wide range of plant species, mainly grasses. fungi were isolated from brown spots on rice leaves throughout peninsular malaysia, and 45 isolates were identified as setosphaeria rostrata the isolates were then characterized using morphological and molecular approaches. the mating type was determined using pcr amplification of the mating type alleles, and isolates of opposite mating types were crossed to examine se ...201627474518
crossover fungal pathogens: the biology and pathogenesis of fungi capable of crossing kingdoms to infect plants and humans.the outbreak of fungal meningitis associated with contaminated methylprednisolone acetate has thrust the importance of fungal infections into the public consciousness. the predominant pathogen isolated from clinical specimens, exserohilum rostratum (teleomorph: setosphaeria rostrata), is a dematiaceous fungus that infects grasses and rarely humans. this outbreak highlights the potential for fungal pathogens to infect both plants and humans. most crossover or trans-kingdom pathogens are soil sapr ...201324021881
Displaying items 1 - 31 of 31