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recovery of verbal short-term memory in alcoholics.when given a short-term memory distractor test on the day after admission to the hospital in an intoxicated state, the performance of older alcoholic patients was significantly worse than that of younger alcoholics and on a par with that of alcoholic korsakoff patients. one month later, however, the older patients' performance was comparable to that of the other alcoholics.19762813
pathways of microbial metabolism of parathion.a mixed bacterial culture, consisting of a minimum of nine isolates, was adapted to growth on technical parathion (par) as a sole carbon and energy source. the primary oxidative pathway for par metabolism involved an initial hydrolysis to yield diethylthiophosphoric acid and p-nitrophenol. a secondary oxidative pathway involved the oxidation of par to paraoxon and then hydrolysis to yield p-nitrophenol and diethylphosphoric acid. under low oxgen conditions par was reduced via a third pathway to ...19768005
double-blind comparison of parsalmide and diazepam in anxious and depressive neurotic syndromes.parsalmide- a new drug- is effective in the relief of inflammation and pain. in a double-blind, between-patients, cross-over trial with diazepam in 16 subjects with anxiety and depression, however, it proved less successful in relieving anxiety, though it was on a par with diazepam on an overall evaluation. the daytime somnolence and asthenia observed with diazepam were not observed with parsalmide.197611425
alcohol dehydrogenases from a facultative methylotrophic bacterium.alcohol-oxidizing enzymes of the facultative methylotroph par were investigated after growth of the bacteria on methanol and ethanol. during methanol growth only a phenazine methosulfate-linked alcohol dehydrogenase was detected. this enzyme had broad specificity for primary alcohols and was also capable of oxidation of secondary alcohols. it had a molecular weight of 112,000, was composed of two subunits of equal molecular weight, and showed an absolute requirement for ammonium ion for activati ...197827500
or/par cooperation for better patient care. 197655098
effects of denervation on the rate of entry of inorganic phosphate into rat slow and fast muscles: selective inhibition of denervation changes by actinomycin d.actinomycin d abolishes the post denervation increase in inorganic phosphate flow observed in the fast gastrocnemius muscle. in the slow soleus muscle, the initial decrease in phosphate flow is unaffected but the secondary rise is suppressed in the same manner as in the fast muscle. these observations put the post denervation increase in inorganic phosphate flow on a par with the development of extrajunctional cholinergic receptors in being the result of the synthesis of new proteins. it has the ...197883829
safety of post-abortion sterilisation.data from the confidential enquiry into laparoscopy, a survey of many operations performed in the united kingdom, from 1976-1977, are presented to determine the relative incidence of complications of concurrent vaginal approach abortion/sterilization, vaginal approach sterilization alone, and other sterilizations. of 11,459 cases sterilized alone using only electrocoagulation, 314 complications arose, for a 2.7% rate. of 1672 sterilizations with terminations, by vaginal approach, using electro ...197991751
transcriptional regulation of escherichia coli k-12 major outer membrane protein 1b.eleven independent insertion mutations were isolated that prevented expression of major outer membrane protein 1b. seven of the mutations were mucts insertions located at ombp. these ompb::mucts strains fell into two phenotypic classes with regard to expression of proteins 1a and 1b. the remaining four mutants were comprised of one tn5 and three mucts insertions mapping at par. the mucts insertions at par were used to construct fusions of the lac operon to the par promoter. expression of beta-ga ...1979115844
generation of cytolytic t lymphocytes in vitro. viii. failure of anti-rs antisera to inhibit the generation of cytolytic t lymphocytes or cytolytic t lymphocyte activity.antibody reactive with "recognition structures" (rs) of mouse lymphoid cells for alloantigens (anti-rs) was prepared by immunization of f1 hybrid mice with parentalstrain lymphoid cells or with antibody produced in one parental strain against alloantigens of the other parental strain. such antisera prevented generation of the "product of antigenic recognition" (par) that is produced within a few hours in cultures prepared with a mixture of lymphoid cells from genetically disparate mice. however, ...1976133188
studies of viral antibody responses among amish families.serum antibodies to adenovirus (adn), cytomegalovirus (cmv), herpes simplex virus (hsv), influenza (inf), para-influenza (par), mumps (mum), coxsackie b4 (cox b4) and b5 (cox b5) viruses were measured from 584 individuals belonging to 21 indiana amish families. sex and age effects on antibody responses to cytomegalovirus were observed. age effect on cmv, hsv, inf, par, mum responses were also found. the percentage of responders to some of the viruses was shown to be age dependent, but the levels ...1977192798
the mapping of mutations in trna and cytochrome oxidase genes located in the cap-par segment of the mitochondrial genome of s. cerevisiae. 1977203841
[usage of the gel filtration method for the determination of urinary proteins (author's transl)].the urinary proteins determination was carried out after purification by gel filtration over sephadex rosin. the proteins eluaded react with biuret-reagent to establish the coloured copper-proteins complex. if proteins concentrations is inferior, the proteins can be determinated by the copper-proteins complex isolation with second gel filtration and titrating cu++ with reactives: dietildithiocarbamate or the par (4-(2pyridyl-azo)resorcinol monosodium salt).1979233432
clinical assessment of a new local anesthetic agent-carticaine.the combination of 4 per cent carticaine 5 mug per milliliter with epinephrine is an effective agent acting in the standard lidocaine-epinephrine-mepivacaine-epinephrine range. like lidocaine, it is of no clinical value without the addition of epinephrine and its vasodilator properties are greater than those of mepivacaine or prilocaine. its onset time is reasonably rapid, its duration and extent are satisfactory for clinical purposes, and no toxic reactions were noted in the 100 injections give ...1977264643
[radiographic magnification technique with a high-speed rare-earth screen-film system (author's transl)].the advantages of radiographic magnification technique - better detail recognition and improved contrast with an enlarged field of vision - should prove an important supplement to the properties of a high-speed rare-earth system - low-current intensity, low voltage, short exposure time and, consequently, lower irradiation dosage. physical measurements of the wiener spectral value, mtf and hd curve proved the superiority of the radiographic magnification technique in combination with a rare-earth ...1977270255
[report on the capsule dosage and mixing system. 3. suitability testing from a technological and clinical point of view].the results from experiments with composite filling materials, silicate cements, stone cements, polyacrylate cements, eba cements and amalgam testify to the suitability of a mixing apparatus already presented (cf. par ii). apart from industrial predosed products, well known multicomponent materials prepared until now manually, among which evicrol, were mixed mechanically.1978274850
the par agreement. 1978290715
studies on the product of antigenic recognition. iii. nature of par.the product of antigenic recognition (par) is an antigen-antibody complex with granulotactic activity. the following results support his conclusion. par generated by cell-bound or shed t-cell rs or the recognizing structure of t alloantisera and alloantigen can be destroyed by heating at 56 degrees c for 30 min, because of inactivation of a heat-labile component supplied by alloantigen. recognizing partners of these complexes are heat-stable. they form par anew when alloantigen is added or upon ...1977300336
studies on the product of antigenic recognition. i. formation of the product in recognition of alloantigens.a product of antigenic recognition (par) was produced whenever receptors for alloantigens from t lymphocytes or a principle present in t-cell dependent alloantisera interacted with alloantigen. with two forms of the par assay (direct and indirect) the mechanisms underlying these interactions have been analyzed. for the interaction of t-lymphocyte receptors with alloantigen measured with direct par assays, the following conclusion emerged: upon confrontation with alloantigen, receptors (if not al ...1977300337
studies on the product of antigenic recognition. ii. formation of the product in recognition of alloreceptors.cell-bound or shed t-lymphocyte receptors for alloantigens and the igg-associated, alloantigen-recognizing principle in t alloantiserum reacted with antisera raised against those structures to form a product of antigenic recognition (par) in which the receptor or its equivalent took the role of 'antigen'. formation of par was tested for numerous combinations of reactants and in all the process was completed within 1-2 h at 37 or 4 degrees c. cell-bound receptors were found to be solubilized by a ...1977300338
the mitral plication suture: a new technique of mitral valve repair.during 1975, 67 patients underwent attempted repair of mixed mitral valve disease by use of the new mitral plication suture (mps) technique. ninety per cent had successful repair and 10 par cent required valve replacement. the mps is a double, semicircular, buttressed annuloplasty suture that constricts the enlarged mitral annulus to correct mitral regurgitation (mr), supports mitral subunit repair procedures, and yet maintains the flexibility of the mitral annulus. the hospital mortality rate w ...1977320402
outer membrane proteins of escherichia coli. vi. protein alteration in bacteriophage-resistant mutants.protein 1 was shown to be the receptor for phage pa-2 by the observations that the purified protein inactivates the phage, mutants lacking the protein are resistant to the phage, and mutants selected for pa-2 resistance have altered protein. protein 1 appears as two bands (1a and 1b) on high-resolution polyacrylamide gels. the most abundant classes of mutants (pari and parii) selected for pa-2 resistance were found to lack band 1b. the mutations responsible for the pari and parii phenotypes were ...1977328489
fine structure physical mapping of 4s rna genes on mitochondrial dna of saccharomyces cerevisiae.we have localized the genes for mitochondrial 4s rna on the physical map of the mtdna of several saccharomyces cerevisiae strains by hybridization of iodinated 4s rna to the restriction fragments obtained with endonucleases hindii + iii, ecori and hapii. the data indicate that 5-8 of the 4s rna genes are dispersed over a large area of the genome whereas the rest (about 18 genes) is located within an area of about 9000 bp in length (about 18 genes) is located within an area of about 9000 bp in le ...1977337105
outer membrane proteins of escherichia coli. vii. evidence that bacteriophage-directed protein 2 functions as a pore.protein 1, a major protein of the outer membrane of escherichia coli, has been shown to be the pore allowing the passage of small hydrophilic solutes across the outer membrane. in e. coli k-12 protein 1 consists of two subspecies, 1a and 1b, whereas in e. coli b it consists of a single species which has an electrophoretic mobility similar to that of 1a. k-12 strains mutant at the ompb locus lack both proteins 1a and 1b and exhibit multiple transport defects, resistance to toxic metal ions, and t ...1978346560
new major outer membrane proteins found in an escherichia coli tolf mutant resistant to bacteriophage tuib.cell envelopes prepared from an escherichia coli tolf strain selected as resistant to phage tuib contained a new major outer membrane protein related to outer membrane proteins ia and ib. the strain that produces this protein is a tolf par double mutant but contains an additional mutation leading to the production of the new major outer membrane protein. antibiotic sensitivity lost as a result of the tolf mutation is regained in strains that contain the new major outer membrane protein. this ind ...1978346577
morton amsterdam--preceptor par excellence. 1977352116
hemodynamic effects of dopamine in patients with resistant congestive heart failure.twelve patients with clinical and hemodynamic evidence of severe congestive heart failure, unresponsive to the usual therapy of salt restriction, oxygen, bed rest, digitalis, and massive doses of diuretics, were studied during a control period and after intravenous dopamine. seven patients survived and 5 died with intractable failure and shock despite transiently improved hemodynamic indices. at control period and after optimal dose of dopamine, there were no significant changes in heart rate (h ...1978354838
[bacteriological examination of cerebro-spinal fluid: suggested techniques (author's transl)].the authors are considering the various tests used in the bacteriological examination of the cerebro-spinal fluid and thence to try to find a simple reliable method of which they recommend the par-test must be an indispensable part. in the appendix they are suggesting some quick additional diagnostic test.1977356774
identification of three genes controlling production of new outer membrane pore proteins in escherichia coli k-12.escherichia coli k-12 strains carrying mutations in the ompb gene or double mutations in the tolf and par genes lack the major outer membrane proteins 1a and 1b. these strains are deficient in the transport of small hydrophylic compounds and are multiply colicin resistant. when revertants of these strains were sought, a number of extragenic pseudorevertants were obtained which produced new outer membrane proteins. these new proteins could be divided into three classes by differences in electroph ...1978357416
lactose variability of escherichia coli in thermally stressed reactor effluent waters.lactose-utilizing and nalidixic acid-resistant populations of escherichia coli, having an optimum growth temperature of 37 degrees c, were placed in modified diffusion chambers. the chambers were submerged in the epilimnion and hypolimnion of a 1,100-hectare lake (par pond) which receives cooling water from a nuclear production reactor. control chambers were placed in a deep-water reservoir and a flowing-streams laboratory, both of which had comparable temperatures to par pond. the populations o ...1978365111
inhibition by itaconate of growth of methylotrophic bacteria.the effects of the isocitrate lyase-directed growth inhibitor itaconate on the growth of certain methylotrophic organisms was investigated. it was found that growth of those organisms possessing the icl(+)-serine pathway of one-carbon metabolism was inhibited during growth on methylamine and on acetate, but not on glucose. organisms possessing the icl(-)-serine pathway pathway were unaffected. organism par, an icl(-)-serine pathway type, was not specifically inhibited during growth on acetate. t ...1979374391
biogenesis of mitochondria 51: biochemical characterization of a mitochondrial mutation in saccharomyces cerevisiae affecting the mitochondrial ribosome by conferring resistance to aminoglycoside antibiotics.an examination of the effect of the aminoglycoside antibiotics paromomycin and neomycin on mitochondrial ribosome function in yeast has been made. both antibiotics are potent inhibitors of protein synthesis in isolated mitochondria. with isolated mitochondrial ribosomes programmed with polyuridylic acid (poly u), the drugs are shown to inhibit polyphenylalanine synthesis at moderately high concentrations (above 100 microgram/ml). at lower concentrations (about 10 microgram/ml), paromomycin and n ...1979386034
[controlled clinical trial of a new antibiotic "cm 9164" (midecacin) in dental and stomatological practice].the action of a new antibiotic identified as cm 9164 ("midecamycin") and provisionally called "midecacin", has been experimented on patients admitted for dental conditions. the research was carried out on an open basis and erythromycin was used as a comparison. after a short review of the chemicophysical properties and toxicological and pharmacological features of midecamycin, the purpose, materials and methods of the research, which was done on two groups of patients, are presented. the results ...1979399319
uranyl-labelled antibody (ula) method and its application for rh antibodies.the existent labelling materials for studies of antigen--antibody interaction at ultrastructural level, namely ferritin and peroxidase, because of their large molecular size do not fulfill all requirements of excellent markers for electron microscopy (em). uranyl acetate has a molecule 354 times smaller than igg and its uranium atom is electron-dense. these physical characteristics of uranyl acetate make it a labelling material par excellence as described in this article. quantitative and qualit ...1978413869
[case report on a myocardial ischemia due to medical tocolysis with ritodrin (pre-par) (author's transl)].in the 24 year old former competitive athelete tocolysis with ritodrin (pre-par) was started at 28 weeks gestation in her second pregnancy for premature labor. diffuse cardiac ischemia occurred during the intravenous infusion of ritodrin. the betamimetic drug was the factor which started the myocardial ischemia as evidenced by the serial electrocardiograms. the importance of serial electrocardiograms during treatment with ritodrin is emphasized.1979422024
urinary hydroxyproline in healthy patients and in prostate patients with and without bone metastases.an essential part of the classification of prostate carcinoma is the diagnosis of bone metastases. this was done with 70 patients using x-ray analysis, scintography, determination of the acid and alkaline phosphatase, and pelvic crest biopsy, as well as aspiration of the pelvic and sternal bone marrow. in addition, the hydroxyproline concentration was determined in the 24-hour-urine. the study, which was initially undertaken on a sample group (n = 145), yielded a high correlation between age and ...1979446076
impotence, smoking, and beta-blocking drugs.four patients complaining of erectile dysfunction and using tobacco or propranolol were examined with penile blood pressure measurements and doppler recordings, calculating the penile acceleration ratio (par). after a change in regimen, erectile capacity was restored, par returned to normal, and blood pressure measurements revealed increased systolic penile blood pressure in three patients. the changes, especially in par, indicate a marked penile vascular reaction during smoking and beta-blockin ...1979446783
in vivo effect of suloctidil as an antiplatelet agent.the relationship between the effects of suloctidil in vivo as an antiplatelet agent and in vitro as a modifier of platelet serotonin (5-ht) parameters was investigated. suloctidil was found to be effective in reducing platelet aggregates formation in the retired breeder rat as determined using the platelet aggregate ratio method (par) with an ed50 of 16.1 mg/kg 24 hours post administration. in contrast to the hypothesis that 5-ht depletion is involved in the anti-aggregatory mechanism of sulocti ...1979462414
subfractionation of cscl-purified h-1 parvovirus on metrizamide gradients.the different density classes of h-l parvovirus, collected within 30 hr of infection of par-asynchronous cultures, following the standard cscl purification step, have been shown to be heterogeneous. rebanding of the denser form (hf, p = 1.46 g/cm3) and the less dense form (lf, p = 1.42 g/cm3) of infectious virus in the nonionic density generating solute, metrizamide, showed that both hf and lf virus bands were heterogeneous in density. the infectivity banded with isotopically labeled virus prote ...1979462819
olivanic acids, a family of beta-lactam antibiotics with beta-lactamase inhibitory properties produced by streptomyces species. ii. isolation and characterisation of the olivanic acids mm 4550, mm 13902 and mm 17880 from streptomyces olivaceus.the olivanic acids mm 4550, mm 13902 and mm 17880 are members of a new family of beta-lactam antibiotics. an isolation and purification process utilising ion-par extraction and ion-exchange chromatography is described and the metabolites are characterised by physico-chemical and biological properties.1979468716
[the value of electrophoretic studies of urinary proteins in clinical practice].a brief account of the physiopathology of proteinuria is followed by a description of the diagnostic routine to be followed in such cases, with particular reference to the electrophoretic study of urinary proteins. in many cases, this simple method gives information on a par with that offered by biopsy, especially insofar as the planning of treatment is concerned. several clinical cases are cited by way of illustration.1979481796
schizoaffective illness defies the dichotomy...and keeps dsm-iii pondering.models proposed to account for patients eventually labeled "schizoaffective" are traced historically. it is demonstrated that these patients represent a distinct clinical entity, and diagnostic criteria are then applied to reevaluate the position of schizoaffective disorder in our current and future nosology. schizoaffective illness is held to be the example, par excellence, that defies the validity of kraepelin's original dichotomy.1979482877
influence of moderate and strenuous daily physical activity on fibrinolytic activity of blood: possibility of plasminogen activator stores depletion.fibrinolysis was studied in 10 alpinists during regular physical activity of different intensity. blood was sampled at rest and after exposure to submaximal workload on the treadmill on three occasions: before and after 6 months physical conditioning (moderate physical activity), and after 6 weeks of an alpinistic expedition (strenuous physical activity). measurements included submaximal working capacity, fibrinogen, euglobulin clot lysis time (elt), whole plasma clot lysis time, and estimations ...1979483247
effect of para-methoxyphenylethylamine on chronic stress-induced hypertension in the rat.this report presents data showing that par-methoxyphenylethylamine is effective in both preventing and reversing chronic stress-induced hypertension in the rat.1979510493
physiological effects of increased tissue pressure.the physiological effects of increased tissue pressure were studied using a model system in which known pressures were applied uniformly to the hindlimbs of rabbits for a period of 5 h. muscle blood flow was monitored using a new argon washout technique. muscle po2, pco2, and par were measured using a teflon membrane catheter-mass spectrometer system. the myoneural conduction velocity served as a measure of the functional status of the limb. higher tissue pressures led to successively greater co ...1979528092
genetic variation in hawaiian drosophila. viii. heterozygosity and genic changes in isolated populations of d. engyochracea.drosophila engyochracea, an endemic hawaiian fly found only in two, finite populations in volcano national park, has extensive electrophoretic heterozygosity on a par with that found in species with much wider distributions. a study of six polymorphic loci in both populations over an 18-month period revealed that the population in the more xeric environment is more dynamic genetically as well as more variable. in addition, genetic changes at one locus, pgm, are correlaed to changes in an environ ...1979540011
[congenital atrial flutter with hydrops fetalis caused by tocolytic therapy (author's transl)].a 31-year-old healthy woman received ritodrine (pre-par) from the 26th week of gestation because of twin pregnancy. three weeks before birth continous intravenous medication with the same drug was commenced because of premature uterine contractions. five days later a heart rate of over 200/minute was noted in one of the twins. this tachycardia persisted until birth while the heart rate of the other twin remained normal. at 33 weeks monozygotic female twins were delivered after artifical rupture ...1979572891
health care, american style: helter skelter, par excellence. 1977584498
[gluconeogenesis in the liver of rats receiving 1,3-butanediol in their diet].inclusion of 1,3-butandiol as a synthetic source of nutritional energy into the composition of a low-carbohydrate diet produced a fall in the ration of free [nad+]:[nadn] and [nadp]:[nadpn] calculated for the cytoplasm and mitochondria of the liver cell in rats according to the concentration of oxidated and reduced metabolites and the equilibrium constant of the lactate-dehydrogenase, glutamate-dehydrogenase and malic-fermentative systems. in these conditions the concentration of metabolites, at ...1977602096
effect of steroids on the adenohypophyseal gonadotrophes & its relation to spermatogenesis in rana hexadactyla lesson.the exogenous administration of selected steroids to male rana hexadactyla lesson was used to investigate the hypophyseal-testicular axis and to determine their influence on the activity of the hypophyseal cell types and the impact of this activity on spermatogenic activity. the frogs were treated as follows: 1) stilbestrol (s), 1.25 in 1 ml ringer as a single dose or in 1.25 ml ringer in .25 ml doses every 48 hours for 15 days 2) testosterone (t), 1 mg/ml every day for 15 days; 3) estradiol ...1977611087
[secretion of ochratoxin a in rabbit milk].the excretion of ochratoxin a in rabbit female was examined after a single intravenous administration of toxin. for the highest dose (4 mg par kg), the level in milk reached 1 ppm. the mammary excretion was also studied while plasma concentration of ochratoxin a was constant; the percentages of protein bound toxin in plasma and milk were determined. the likeness of theoretical and experimental ratio between mycotoxin levels in milk and plasma ultrafiltrates allowed to conclude in favour of the p ...1977613941
[the demonstration of antibacteric power in a blood sample taken for blood culture. preliminary note. (author's transl)].to identify a possible "false" negative blood culture from a patient not declearing antibiotic treatment, we propose a "residual antibiotic power" test (par-test) on the same blood sample to be rum in parallel with the blood culture. hence we propose using b. stearothermophilus var. calidolactis, which we have found very sensitive to the common antibiotics used in human medicine. suggested technique: agar+germ with an absorbent paper disc soaked with the sample, incubated for 3 hours at 60 degre ...1977616251
the nose provocation and the passive anterior rhinometry (par).the authors describe an easy and fast way of nose provocation (aerosol provocation combined with passive anterior rhinomanometry). a comparative study between skin tests, lungprovocations and noseprovocations proves the usefulness of the method.1978622903
pulmonary hemodynamics and right ventricular function in hypertension.pulmonary and systemic hemodynamics in 16 hypertensive subjects (group i) with left ventricular (lv) hypertrophy (ecg and echo criteria) and in 17 hypertensive subjects with ecg signs of lv strain (group ii), were compared with those in 14 normal individuals. an augmented pulmonary arteriolar resistance (par) in group i and to a larger extent in group ii accounted for the pulmonary pressure elevation in both groups. increase in par was unrelated to pulmonary blood flow and volume, pleural pressu ...1978639242
[obstetrics and gynecology in the undergraduate medical curriculum].in the present situation where medical curricula are being re-examined by many medical faculties, the importance of obstetrics and gynaecology in the undergraduate curriculum has come under intense scrutiny. obstetrics and gynaecology form a major part of the general practitioner's work, and should therefore form a major part of his medical training. the subject also stresses par excellence the importance of communication with patients, preventive medicine and special responsibility of the medic ...1978653498
[dental receptor projections to the sensomotor zone of the rabbit cerebral cortex].topic organization of the dental representation was studied in experiments on rabbits by the method of induced potentials. every tooth proved to be locally represented in the sensory-motor zone of the brain cortex. these zones do not overlap in the case of stimulation of the threshold strength. topic dental projection region occupies a territory including fields par i, praecag, preacgr, and pc.1978667337
emerging cholinergic mechanisms and ontogeny of response inhibition in the mouse.mice, 7, 11, 15, 19, and 85-115 (adult) days of age, served as subjects in experiments assessing effects of anticholinergics on the development of behavioral inhibition. the centrally active anticholinergic scopolamine produced a dose-dependent elevation in locomotor activity in 19-day-old and adult mice. acquisition and retention of a step-off passive avoidance response (par) was initially studied in nondrugged subjects. mice as young as 7 days of age learned and retained the par for 1 hr. twen ...1978670457
comparative effects of chronic ethanol and acetaldehyde exposure on myocardial function in rats.this study was conducted to compare separately the chronic effects of high blood levels of ethanol and acetaldehyde on the metabolism of the heart. levels of ethanol and acetaldehyde were altered by administration of either 4-methylpyrazole (4-mp), a potent alcohol dehydrogenase inhibitor, or pargyline (par), a monoamine oxidase inhibitor that markedly increases acetaldehyde levels in the blood following ethanol administration. measurements were made in rats consuming ethanol for three to four w ...1978690249
application of radiographic magnification technique with an ultra-high-speed rare-earth screen/film system to oral cholecystography.2x magnification employing a 200-mu focal spot and an alpha 8-xm screen/film system was applied to oral cholecystography and the results compared with those for the conventional contact technique with the par-rp system. the basic imaging properties of the system, as well as phantom studies, indicated that the image quality obtained with magnification is comparable to or better than that for the conventional technique. in clinical studies on the detection of gallstones, the conventional technique ...1978693872
[penal responsibility and the unconscious conflict].although the same model of the delinquent's penal responsibility still exists in law as well as in psychiatry, it is rapidly giving way to the concept of personality. moreover, the psychoanalytical model is currently being used. the sole point of reference used by the psychiatrist is his relationship with the delinquent. he thus constructs a "new history" for the delinquent. this psycho-dynamic approach to the delinquent makes us formulate two fundamental objections: 1) it often is forgotten tha ...1978694461
perimetry of contrast detection thresholds of moving spatial sine wave patterns. iii. the target extent as a sensitivity controlling parameter.contrast detection thresholds for moving sine wave gratings were obtained at the fovea and at eccentricities of 6 degrees, 21 degrees, and 50 degrees on the nasal horizontal meridian. the targets subtended from 30 x 30 minutes of arc up to 16 degrees x 16 degrees. we have found that the contrast detection thresholds depend critically on the extent of the target field. if this extent is large enough peripheral detection thresholds are on a par with those measured at the fovea, only the sensitivit ...1978702224
[statistical data concerning passive anterior rhinomanometry (par)].the authors measured the values of the passive anterior rhinomanometry (par) obtained from 30 normal subjects and studied the influence of the different variables involved in par. this influence was calculated by using of statistical analysis (anova). by measuring "p" with successively changing flows, it was possible to determine that the airstream was mainly laminair.1978707073
estimation of pulmonary/systemic resistance ratios from echocardiographic systolic time intervals in young patients with congenital or acquired heard disease.previous work has shown the positive correlation of echocardiographic right ventricular preejection period/right ventricular ejection time ratio (rpep/rvet) with pulmonary vascular resistance and pulmonary arterial diastolic pressure obtained at cardiac catheterization. however, the correlation was insufficient to predict pulmonary arterial diastolic pressure or vascular resistance from a given rpep/rvet ratio. in this study the rpep/rvet ratio was compared with left ventricular preejection peri ...1978707293
the effects of pentobarbitone and urethane on pulmonary airway resistance in guinea-pigs and their interactions with drugs.1 propranolol increased pulmonary airway resistance (par) in the conscious guinea-pig, whereas atropine had no effect, suggesting the existence of a continual sympathetic bronchodilator tone. 2 the direct bronchoconstrictor effects of histamine, acetylcholine and 5-hydroxytryptamine were modified by autonomic reflexes: a bronchodilator one, abolished by propranolol, and a cholinergic bronchoconstrictor one, seen with histamine. 3 pentobarbitone increased par, an effect which was reduced by propr ...1978728681
[rationalisation of the roentgenodiagnostical result with par and their results (author's transl)]. 1978734117
pulmonary and systemic hemodynamic effects of delta9-tetrahydrocannabinol in conscious and morphine--chloralose-anesthetized dogs: anesthetic influence on drug action.pulmonary and systemic hemodynamic effects of delta 9-tetrahydrocannabinol (delta 9-thc) in conscious dogs and in those anesthetized with morphine (3 mg/kg, i.m.) plus alpha-chloralose (100 mg/kg i.v.) were evaluated in this study. a decrease in the heart rate, cardiac output (pbf) and a concomitant increase in the pulmonary arterial pressure (pap), pulmonary vascular resistance (pvr) and right ventricular stroke work (rvsw) observed in conscious animals following the administration of delta 9-t ...1978738360
[the vitamin b 1 nutritional status of the pregnant rat and its litter as a function of dietary thiamine supply].influence of the dietary supply in thiamine on the vitamin nutritional status of the gestating female rat and of the litter. four groups of gestating female rats were fed diet containing respectively 2, 4, 6, 8 mg of thiamine par kg. in every group, urinary excretion of thiamine was found to be stable up to the 16th day of gestation and then to decrease markedly during the 5 last days. this result and those concerning the changes in vitamin excretion, as related to the dietary intake, support th ...1978738847
the parasite fauna of the american alligator (alligator mississippiensis) in south carolina.twelve american alligators (alligator mississippiensis) were obtained from three different areas of south carolina. one species of pentastome (sebekia oxycephala), two species of nematodes (dujardinascaris waltoni and multicaecum tenuicolle), four species of trematodes (polycotyle ornata, acanthostomum coronarium, archaeodiplostomum acetabulatum and pseudocrocodilicola americaniense) and one species of hemogregarine (haemogregarina crocodilnorum) were recovered. polycotyle ornata was observed on ...1978739582
[neuropathy in long term treatment with metronidazole (author's transl)].two patients developed a sensory neuropathy while under treatment with metronidazole for crohn's disease. recovery took place within a few months after drug withdrawal but was still incomplete in one patient one year after cessation of metronidazole intake. the incidence of neuropathy appears to be high in long term use of this drug. the morphological study of a sural nerve biopsy showed a severe loss of myelinated fibers (1 800 par mm2). quantitative teased fibers preparation showed that 56 per ...1978749126
effect of antibiotics on the results and complications or thoracic operations. par ii.the role of antibiotics in the therapeutical result and in the postoperative complications was studied after 557 thoracic operations. it was found that antibiotics have no decisive role in the therapeutic result and there was no difference in the incidence of wound infections between the groups treated with different antibiotics. the principles and practice of treatment of would infections and pyothorax are discussed in detail. no relationship was found between the incidence of postoperative res ...1978755316
genetic analysis of petite mutants of saccharomyces cerevisiae: transmissional types.we have studied a number of petite [rho-] mutants of saccharomyces cerevisiae induced in a wild-type strain of mitochondrial genotype [ome- chl(r) ery(s) oli(s) (1, 2, 3) par(s)] by berenil and ethidium bromide, all of which have retained two mitochondrial genetic markers, [chl(r)] and [ery(s)], but have lost all other known markers. though stable in their ability to retain these markers in their genome, these mutants vary widely among themselves in suppressiveness and in the extent to which the ...1976773749
relation between salmonella typhimurium biotypes and drug resistance, teheran, iran (1962-1973).according to the procedure of cordano (1971), the identification of biotypes of 118 strains of salmonella typhimurium isolated from stools or rectal swabs of patients with sporadic cases of diarrhoea on the central plateau during the period 1962-1973 revealed that: from 118 s. typhimurium, 65 (55-1%) were biotype "d", 50 (42-4%) were "a" and three (2-5%) were "b". the predominant biotype was "d", followed by the "a" biotype, and "b" was rarely encountered. biotype "d" has existed since 1965, and ...1976775118
[etude de l'absorption des graisses par la mesure de la radioactivité spécifique expirée]. 1976775434
[controlled clinical trial of parsalmide, a drug with analgesic and anti-inflammatory activity].a controlled clinical trial of the anti-inflammatory, analgesic, muscle-relaxing and anxiolytic activity of a new compound (parsalmide) was compared with that of phenybutazone in 40 patients with acute or exacerbated inflammatory or degenerative processes randomly distributed into two treatment groups. parsalmide was more effective in the relief of joint swelling and anxiety and gave better motility. on an overall evaluation, however, it was on a par with phenylbutazone. treatment had to be susp ...1976792737
[results of a multi-center, international clinical trial of difluocortolone valerate (nerisona)].the new corticosteroid diflucortolone valerate was clinically investigated in an international, multi-centre trial by a total of 162 dermatologists in 22 countries in more than 6,285 patients with inflammatory and allergic skin diseases. depending on the condition of the skin, diflucortolone valerate was applied as a cream, ointment or fatty ointment at a concentration of 0.1%. most of the patients treated with the cream displayed weeping skin conditions. the ointment was used mainly in patients ...1976795179
on the formation of rho- petites in yeast. i. multifactorial mitochondrial crosses (rho+ x rho+) involving a mutation conferring temperature-sensitivity of rho factor stability.the inheritance of an extrakaryotic mutation conferring temperature-sensitive growth on non-fermentable substrates and a high frequency of mutation to rho- has been studied. multifactorial crosses (rho+ x rho+) involving this mutation ts8 and mitochondrial mutations conferring resistance to chloramphenicol, erythromycin, oligomycin or paromomycin revealed: a) mutation ts8 is localized on the mitdna, referring to a new gene locus tsm1. b) locus tsm1 appears to be weakly linked to the locus par1 a ...1976799250
t-lymphocyte receptors for alloantigens.recent developments in research on t-cell receptors for alloantigens have been reviewed. recognition of these antigens is t-cell dependent and, when measured in the par test, can be shown to take place with receptors present on t cells, with those shed spontaneously from t cells and also with "recognition structures" of as yet unknown origin and structure present in post-transplantation alloantiserum but absent from b-cell induce alloantiserum. all recognizing structures of parent t-cell origin ...1976799619
selenium in biology.the role of se in biology appears from the evidence now at hand to be as a catalyst par excellence. as unique prosthetic group of a variety of enzymes, presumably as se(2-), se functions with tocopherol to protect cell and organelle membranes from oxidative damage, to facilitate the union between oxygen and hydrogen at the end of the metabolic chain, and to transfer ions across cell membranes, in protein synthesis in erythrocytes and in liver organelles, in immunoglobulin synthesis, and in ubiqu ...1975807152
avoidance behavior and ileum motility post-cingulumotomy in monkey.two experiments were conducted utilizing rhesus monkeys to determine (i) the effects of cingulumotomy on conditioned-avoidance acquisition and extinction and (ii) the effects of avoidance learning on distal ileum motility in control- and cingulum-lesioned animals. active (aar) and passive (par) avoidance schedules singly or in combination were employed during short daily periods (less than 2 hr) of "shaping," training, acquisition, and extinction. the data indicated that the control-lesion and c ...1976822886
[further studies of the cytoarchitectonic division in the dorsal surface of the lst temporal gyrus of a linguistic genius and 2 anthropoids].1. as an addition to already published studies in this journal (beheim 1974) about the cytoarchitectonic divisions in six left human dorsal surfaces, the left and the right dorsal surface of a linguistic genius and of two anthropoids were examined; a second human right dorsal surface was used for a comparison. 2. in all these cases it was possible to confirm the presented in the first article dividing characteristics of the described partitions of the cortex in spite of considerable cytoarchitec ...1975824878
indirect chelatometric determination of piperazine in some pharmaceutical preparations.an indirect complexometric method is described for the determination of piperazine alone or in its pharmaceutical preparations. the method involves treatment of the aqueous solution of piperazine with carbon disulphide, ammonia solution and a known excess of cupric acetate, filtration of the formed precipitate and determination of the excess cupric acetate with edta using par as indicator.1976828271
[dosage of prolactine in normal and pathological subjects (author's transl)].homologous radioimmunoassay of human prolactin was performed and used to investigate the secretion of this pituitary hormone under normal and pathological conditions. the following data were developed in this paper: --during the menstrual cycle, prolactin levels are more elevated during ovulatory and luteal phases than during follicular phase; --during pregnancy, prolactin levels progressively increase to reach their maximum at the end of gestation; --during lactation, prolactin levels increase ...1976828474
noise reduction by radiographic magnification.effective noise in the rare-earth system can be substantially reduced by use of radiographic magnification technique. the basic imaging properties of the rare-earth system (alpha 8-xm) and the medium-speed system (par-rp) were evaluated by the wiener spectra, modulation transfer functions, and h&d curves. the visibility of radiographic details was determined with simple test objects. results indicate that, as the magnification increases, the effective noise in the rare-earth system is reduced, a ...1977834899
photoactivation ratios for specification of high-energy x-ray quality: part i, 15-40-mv x rays.a sensitive and relatively simple method for obtaining an index of the spectral quality of high-energy x rays is presented. the method is based upon the use of photoactivation threshold detectors. photonuclear reactions produce measurable amounts of radioactivity for radiation exposures of several thousand roentgens. since the threshold energies for photonuclear reactions vary for different nuclei, the ratio of radioactivity induced in two appropriately selected foils is very sensitive to the x- ...1977840186
photoactivation ratios for specification of high-energy x-ray quality: part ii, 4-15-mv x rays.a sensitive and relatively simple method for obtaining an index of the spectral quality of x rays in the 4-15-mv range is presented. the method is based upon the simultaneous production of 115min by inelastic scattering of x rays by an indium foil and the production of 116min by neutron capture, where the neutrons are obtained from the photodisintegration of deuterium. since the cross sections for the production of 115min and 116min have markedly different energy response functions, the ratio of ...1977840187
adoption in evolution: recent influences on adoption in virginia.adoption is a relatively new and evolving institution. the characteristics of children available for adoption are changing. some hard-to-place children will be helped by subsidized adoption. the concept of children as property of biologic parents continues to shadow efforts to terminate parental rights. virginia law allows adoption against parental consent if such consent is withheld contrary to the child's welfare, but decisions continue to be based upon whether or not parental behavior has bee ...1977841392
echocardiographic criteria of the diagnosis of mitral-semilunar valve continuity.a prospective echocardiographic study of 39 healthy adults with no history of heart disease was conducted to investigate the relationship between the anterior mitral valve leaflet (amvl) and the posterior aortic root (par). the difference between the echocardiographic depth of the amvl and the depth of the par with respect to the chest wall (cw) echoes was measured from both the third and fourth intercostal spaces in both the supine and left lateral positions. the results indicate that there wer ...1977851056
effects of melanocyte-stimulating hormone (msh) and melatonin on passive avoidance and on an emotional response.the present experiment investigated the opposite effects of synthetic alpha-msh and melatonin on acquisition and extinction of a passive avoidance response (par) and on emotionality, as indexed by defecation, in the pa box. it was found that intraperitoneal (ip) administration of alpha-msh delayed extinction and increased defecation responses whereas ip administration of melatonin facilitated extinction of the par and decreased defecation. the present experiment confirmed msh-melatonin oppositio ...1977882581
long-term results of the mustard procedure.over a 10-year period, 123 patients with transposition of the great vessels underwent the mustard procedure. the hospital mortality for the series was 10.6%. there were seven late deaths, five of which were presumable due to arrhythmia. sinus rhythm was noted postoperatively in 53% of the patients. almost all the survivors had achieved catch-up growth when evaluated 6 months to 10 years later. a growth spurt was more consistently seen in the patients who were operated on under 2 years of age. ph ...1977884833
a long term evaluation of infants who received a beta-mimetic drug while in utero.the administration of beta-mimetic drugs to pregnant women poses the problem of possible long-term repercussions in the children born to these mothers. 42 children from women who had been treated with 60-80 mg a day of ritodrine hydrochloride (pre-par), during a period varying from 3 to 93 days, were closely matched with infants from untreated mothers. each child, (aged from one to 3 years), was fully investigated on the basis of: a detailed questionnaire to the mother; careful clinical examinat ...1977894466
neurophysiological measures and visual averaged evoked responses in psychiatric patients. relationship to monoamine oxidase activity in platelets.in 57 consecutive patients with psychiatric disorders correlations were sought between the neurophysiological variables - amplitudes and latencies of visual averaged evoked responses (vaer), the proneness to augment or to reduce the amplitude of vaer with increasing stimulus intensity, par and pri, the mean integrated amplitude (mia) and its within patient variance (wpv) and the monoamine oxidase activity (mao) in platelets, both with beta-fenylethylamine (mao1) and with tryptamine (mao2) as sub ...1977896004
interlaminer connections of rat visual cortex: an ultrastructural study.thermal lesions were made in layers i, ii, and upper par of layer iii of rat visual cortex. the distribution of degenerating axons and axon terminals in layers iv, v, and vi was studied using electron microscopic techniques. following supragranular thermal lesions, the majority of degenerating axon terminals were found in layer v, with extension into the adjacent part of layer vi. neural profiles postsynaptic to degenerating axon terminals were found in these layers in the following distribution ...1977903416
[value of the nose provocation test in the allergic patient. a comparative study of the correlation skin inhalation, and lung tests provoked with various allergens].the authors make a comparative study in 55 cnlsd children and 10 healthy children. in all those children, provocation tests were performed as wel at the level of the skin, as at the level of the lung and nose. the provocation tests were performed with the following allergens: house dust, mites, human dander and pollen, and with histamine. only in the control group (10 healthy children) no lung provocations with histamine were done. from the investigation follows that skin tests are not always re ...1977920148
[effect of destruction of individual nuclei of the amygdaloid complex on elaboration of avoidance reaction in rats].formation of one-trial passive avoidance reactions (par) after bilateral symmetrical ablations of some nuclei of the amygdala complex (ac) was studied in wistar male rats. some nuclei belonging to the corticomedial or basolateral group of ac nuclei were subjected to electrolythical ablation. it has been found that ablations of individual ac nuclei statistically significantly prevent par elaboration. the data obtained are interpreted from the standpoint of disturbance of the morpho-functional org ...1976941504
the hypothalamo-hypophysial system in acipenseridae. vi. the proximal neurosecretory contact region.the proximal neurosecretory contact region (pcr) of acipenseridae, a homologue of the tetrapod median eminence, has been studied by light, fluorescence and electron microscopy. it occupies the rostral and chiefly the ventral surfaces of the hypothalamic tuber cinereum. paf-positive fibres occur in the zone of the preoptico-hypophysial tract but their terminal enlargements are concentrated mainly in the external zone. they make contact with the primary portal capillaries situated in the pia mater ...1976949734
changes in rat respiratory behavior under varying pco2 levels and argon content in hyperbaric ar-o2-co2 atmospheres.an anesthetized rat preparation has been used for breathing studies in hyperbaric ar-o2-co2 atmospheres in which total saturation pressure was varied in the range 1-19.1 ata and pco2 was set at levels of 0.0, 0.05 or 0.10 ata. the variables monitored were respiration rate and an isotonic measure of diaphragm-twitch amplitude during contracture/relaxation (twitch index). the results indicate that: (1) hyperbaric ar-o2 atmospheres are able to maintain the animal in stable condition for several hou ...1976951828
autonomic influences and cardiac conduction in patients with sinus node disease.18 patients with sinus bradycardia (8 sb) and tachycardia-bradycardia syndrome (10 tbs) were investigated using various vagan reflex manoeuvres, atrial pacing (ap), pharmacological tests and his bundle (hb) recordings, to assess autonomic influences, sinus node function and atrioventricular (av) conduction. three types of responses (r) were defined as normal (n), supernormal (sn), poor autonomic (pa). poor reflex responses to vagal manoeuvres, performed in 12 patients, have no statistical signif ...1976975152
seasonal abundance of neoechinorhynchus cylindratus taken from largemouth bass (micropterus salmoides) in a heated reservoir.samples of largemouth bass were collected from par pond located on the energy research and development administration's savannah river plant in aiken, south carolina, from june 1972 to may 1973 inclusive. the sampling stations reflected water temperatures which were both normal and greater than 10 degrees c above normal for the area. the acanthocephalan neoechinorhynchus cylindratus was the dominant species found in the bass sampled. incidences of infection for this parasite were generally great ...19761012752
[world trends in infant mortality since 1950].despite the considerable progress made in recent decades, and perhaps even partly because of the very uneven distribution of this progress, infant mortality is still very high in some regions, whereas in other regions it is tending, if not disappear completely, at least to become numerically negligible even though remaining a matter of social concern. whereas in tropical africa almost one child in five dies before its first birthday, in japan or scandinavia it is one child in a hundred. infant m ...19761014712
[contribution to the psychoanalytic theory of exhibitionism].exhibitionism can be regarded as a cultural, social and psychological phenomenon. it is given a view of the theories in the literature. once exhibitionism is a normal human phenomen, otherwise it is pathological, par example also a neurotic symptom. the early psychoanalytic theories describe exhibitionism as a "psychoneurose" as a result of "odiopussituation", "kastrationskomplex" and "inzestwunsch". psychodynamically this is not satisfying. with the development of psychoanalytic theory, especia ...19761014910
hydro- and hemodynamic effects of catheterization of vessels. ii. model experiments comparing circular and annular lumen area reduction.experiments and a simple theoretical analysis have been performed concerning the flow through circular (stenosis) and annular (catheter piece) lumen area reduction of rigid- and elastic-walled vessels. both steady and pulsatile flow at various volumetric flow rates were investigated. a good agreement between the experimental and the analytical results has been found. a critical annular lumen area reduction exists on a par with the well-known critical stenosis. the strongest reduction in pressure ...19761016498
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