| larval settlement of the common australian sea urchin heliocidaris erythrogramma in response to bacteria from the surface of coralline algae. | bacterial biofilms are increasingly seen as important for the successful settlement of marine invertebrate larvae. here we tested the effects of biofilms on settlement of the sea urchin heliocidaris erythrogramma. larvae settled on many surfaces including various algal species, rocks, sand and shells. settlement was reduced by autoclaving rocks and algae, and by treatment of algae with antibiotics. these results, and molecular and culture-based analyses, suggested that the bacterial community on ... | 2006 | 16794830 |
| synthesis of cycloprodigiosin identifies the natural isolate as a scalemic mixture. | the enantiomers of the natural product cycloprodigiosin were prepared using an expedient five-step synthetic sequence that takes advantage of a schöllkopf-barton-zard (sbz) pyrrole annulation with a chiral isocyanoacetate and a nitrocyclohexene derivative. using chiral hplc and x-ray crystallographic analyses of the synthetically prepared material and natural isolate (isolated from the marine bacterium pseudoalteromonas rubra), naturally occurring cycloprodigiosin was determined to be a scalemic ... | 2015 | 26114660 |
| complete genome sequence of pseudoalteromonas rubra scsio 6842, harboring a putative conjugative plasmid pmbl6842. | pseudoalteromonas is a genus of gram-negative and is ubiquitously distributed in the ocean. many pseudoalteromonas species are capable of producing pigments, which can serve as an alternative source to replace synthetic pigments used in the food industry. prodigiosins belong to a family of secondary metabolite characterized by a common pyrrolyl pyrromethane skeleton, and have been successfully applied to yogurt, milk and carbonated drinks as substitutes for synthetic additives. the strain pseudo ... | 2016 | 26970053 |
| efficient preparation of pseudoalteromone a from marine pseudoalteromonas rubra qd1-2 by combination of response surface methodology and high-speed counter-current chromatography: a comparison with high-performance liquid chromatography. | pseudoalteromone a (pa) is a cytotoxic and anti-inflammatory ubiquinone discovered recently from a marine bacterium pseudoalteromonas sp. cgh2xx. in order to meet its sample supply for further in vivo pharmacological investigation, an efficient method was developed for the preparation of pa by combination of response surface methodology (rsm) and high-speed counter-current chromatography (hsccc) from marine bacterium p. rubra qd1-2. first, optimization of culture conditions was studied by the rs ... | 2014 | 24477384 |
| genome sequence of the cycloprodigiosin-producing bacterial strain pseudoalteromonas rubra atcc 29570(t). | the cycloprodigiosin biosynthetic gene cluster has not been reported. we sequenced the genome of a cycloprodigiosin-producing bacterial strain, pseudoalteromonas rubra atcc 29570(t). analysis revealed a probable cycloprodigiosin biosynthetic cluster, providing a good model for the study of cycloprodigiosin synthesis and regulation. | 2012 | 22374963 |
| discovery and structure-based optimization of 6-bromotryptamine derivatives as potential 5-ht2a receptor antagonists. | 5-hydroxytryptamine type 2a (5-ht2a) receptor is an important target for developing innovative antipsychotic agents in neuropsychiatric disorder therapies. to search for 5-ht2a receptor antagonists, a new indole alkaloid termed 6-bromo-n-propionyltryptamine (1), together with one known homologue 6-bromo-n-acetyltryptamine (2) were isolated and identified from a marine bacterium pseudoalteromonas rubra qd1-2. compound 1 with an n-propionyl side chain exhibited stronger 5-ht2a receptor antagonist ... | 2015 | 26404234 |
| bioactivity, chemical profiling, and 16s rrna-based phylogeny of pseudoalteromonas strains collected on a global research cruise. | one hundred one antibacterial pseudoalteromonas strains that inhibited growth of a vibrio anguillarum test strain were collected on a global research cruise (galathea 3), and 51 of the strains repeatedly demonstrated antibacterial activity. here, we profile secondary metabolites of these strains to determine if particular compounds serve as strain or species markers and to determine if the secondary metabolite profile of one strain represents the bioactivity of the entire species. 16s rrna gene ... | 2011 | 21305330 |
| a 2-substituted prodiginine, 2-(p-hydroxybenzyl)prodigiosin, from pseudoalteromonas rubra. | in the course of work aimed at the discovery of new pharmaceutical lead compounds from marine bacteria, a lipophilic extract of the bacterium pseudoalteromonas rubra displayed significant cytotoxicity against skov-3, a human ovarian adenocarcinoma cell line. bioassay-directed fractionation of this extract resulted in the isolation of a series of known and new prodiginine-type azafulvenes. the structure of the major metabolite was elucidated by interpretation of spectroscopic data as a 2-substitu ... | 2008 | 18922034 |
| the structure of the o-polysaccharide of the pseudoalteromonas rubra atcc 29570t lipopolysaccharide containing a keto sugar. | the structure of the phenol-soluble polysaccharide from pseudoalteromonas rubra type strain atcc 29570t has been elucidated using 1h and 13c nmr spectroscopy, including 2d cosy, tocsy, gnoesy, roesy, 1h,13c ghmqc and ghmbc experiments. it is concluded that the trisaccharide repeating unit of the polysaccharide has the following structure: [carbohydrate structure: see text] where sug is 2-acetamido-2,6-dideoxy-d-xylo-hexos-4-ulose, am is acetimidoyl and acyl is a malic acid residue, which is o-ac ... | 2005 | 16126182 |
| pseudoalteromonas bacteriolytica sp. nov., a marine bacterium that is the causative agent of red spot disease of laminaria japonica. | an aerobic, polarly flagellated marine bacterium that produces a prodigiosin-like pigment was isolated from the red-spotted culture beds of laminaria japonica. five isolates had unique bacteriolytic activity for both gram-positive and -negative bacteria, which had never been observed among alteromonas or related species. the isolates were identified as the causative agent of red spot disease of l. japonica seeds. the phenotypic features of the isolates were similar to these of pseudoalteromonas ... | 1998 | 9734030 |
| a novel conico-cylindrical flask aids easy identification of critical process parameters for cultivation of marine bacteria. | a polymethylmethacrylate (pmma) conico-cylindrical flask (ccf) with an inner arrangement consisting of eight equidistantly spaced rectangular strips mounted radially on a circular disk to provide additional surface area for microbial attachment and ports to allow air supply was employed for melanin production by shewanella colwelliana and antibiotic production by pseudoalteromonas rubra. the design allowed comparison of production between (1) ccf with hydrophobic surface (pmma-ccf), (2) ccf with ... | 2011 | 21210106 |
| new prodigiosin-like pigment from alteromonas rubra. | the red prodigiosin-like pigment from alteromonas rubra was shown to be a mixture of prodigiosin (pigment 1) and a new cyclic isomer (pigment 2). the new structure was elucidated by mass and nuclear magnetic resonance spectra. careful examinations of the prodigiosins produced by serratia marcescens, vibrio psychoerythrus, and an unidentified red bacterium (ll-100-6) failed to disclose any of the new pigment, pigment 2. | 1979 | 384909 |
| antifouling activities expressed by marine surface associated pseudoalteromonas species. | abstract members of the marine bacterial genus pseudoalteromonas have been found in association with living surfaces and are suggested to produce bioactive compounds against settlement of algal spores, invertebrate larvae, bacteria and fungi. to determine the extent by which these antifouling activities and the production of bioactive compounds are distributed amongst the members of the genus pseudoalteromonas, 10 different pseudoalteromonas species mostly derived from different host organisms w ... | 2002 | 19709238 |
| structure of a polysaccharide from the lipopolysaccharides of vibrio vulnificus strains cect 5198 and s3-i2-36, which is remarkably similar to the o-polysaccharide of pseudoalteromonas rubra atcc 29570. | high-molecular-mass polysaccharides were released by mild acid degradation of the lipopolysaccharides of two wild-type vibrio vulnificus strain, a flagellated motile strain cect 5198 and a non-flagellated non-motile strain s3-i2-36. studies by sugar analysis and partial acid hydrolysis along with (1)h and (13)c nmr spectroscopies showed that the polysaccharides from both strains have the same trisaccharide repeating unit of the following structure: -->4)-beta-d-glcpnac3nacylan-(1-->4)-alpha-l-ga ... | 2009 | 19695563 |
| phylogenetic analysis of the genera alteromonas, shewanella, and moritella using genes coding for small-subunit rrna sequences and division of the genus alteromonas into two genera, alteromonas (emended) and pseudoalteromonas gen. nov., and proposal of twelve new species combinations. | small-subunit ribosomal dna sequences were determined for 17 strains belonging to the genera alteromonas, shewanella, vibrio, and pseudomonas, and these sequences were analyzed by phylogenetic methods. the resulting data confirmed the existence of the genera shewanella and moritella, but suggested that the genus alteromonas should be split into two genera. we propose that a new genus, the genus pseudoalteromonas, should be created to accommodate 11 species that were previously alteromonas specie ... | 1995 | 7547295 |