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a comparative study of the histopathologic features of bovine tuberculosis in cattle, fallow deer (dama dama), sika deer (cervus nippon), and red deer and elk (cervus elaphus).sections of tuberculous lesions from 23 elk (cervus elaphus nelsoni) and red deer (cervus elaphus elaphus), 12 fallow deer (dama dama), 10 sika deer (cervus nippon), and 30 cattle were examined and compared. lesions were scored for caseous necrosis, mineralization, neutrophils, macrophages, giant cells, and acid-fast bacilli. some differences in lesion morphology between the species were noted. elk/red deer lesions had marked variation and often differed from bovine lesions in several characteri ...19957604487
susceptibility of mule deer (odocoileus hemionus) and two species of north american molluscs to elaphostrongylus cervi (nematoda: metastrongyloidea).an experimental study was done to determine whether elaphostrongylus cervi can be transmitted to common intermediate and definitive hosts indigenous to north america. first-stage larvae of e. cervi obtained from red deer (cervus elaphus elaphus) in new zealand developed to the infective third stage in snails (triodopis multilineata) and slugs (deroceros reticulatum). two mule deer (odocoileus hemionus) were inoculated orally with 102 or 406 third-stage larvae. one animal developed a patent infec ...19957623202
diagnosis of elaphostrongylus cervi infection in new zealand red deer (cervus elaphus) quarantined in canada, and experimental determination of a new extended prepatent period.a modified baermann assay was used to recover dorsal-spined, first stage larvae of elaphostrongylus cervi from feces and lungs of red deer (cervus elaphus elaphus) from three of four herds imported from new zealand into canadian quarantine facilities. tests done on a series of fecal collections showed that larval output from infected red deer was low and sporadic, casting doubt on the efficacy of the baermann assay to detect all infected individuals in the herds. the animals had passed repeated ...19948076289
nematode egg output and plasma concentration of ivermectin after its administration to red deer (cervus elaphus elaphus).blood and faecal samples were analysed in a study to evaluate the use of ivermectin in red deer hinds (cervus elaphus elaphus). it was demonstrated that ivermectin, when used at 400 micrograms/kg bodyweight, proved to be more efficient than 200 micrograms/kg bodyweight although positive worm egg counts together with the isolation of lungworm (dictyocaulus species) larvae were recorded from hinds having received the anthelmintic at the higher dose.19938456547
assessment of domestic goats as a patent host of elaphostrongylus cervi.a study was undertaken to determine whether domestic goats can serve as patent hosts of elaphostrongylus cervi under natural or experimental conditions. three-hundred and two fecal samples from 124 domestic goats raised outdoors in new zealand, where e. cervi is enzootic, were tested for nematode larvae by the baermann method. all samples were negative for e. cervi dorsal-spined larvae. twenty juvenile male nubian and saanen goats obtained locally were assigned randomly to 5 dosage groups and we ...200212053987
an aspartyl protease inhibitor orthologue expressed by parelaphostrongylus tenuis is immunogenic in an atypical host.parelaphostrongylus tenuis is a neurotropic nematode common in white-tailed deer (odocoileus virginianus) of eastern north america. this parasite is the causative agent of a debilitating neurologic disease in atypical hosts, including domestic livestock. in order to identify proteins of potential significance in the host-parasite relationship, a cdna library was produced from adult p. tenuis mrna. screening the library with antisera from infected red deer (cervus elaphus elaphus) and immunized a ...200212093670
identification of antigens with potential for immunodiagnosis of parelaphostrongylus tenuis and elaphostrongylus cervi infections in red deer (cervus elaphus elaphus).red deer (cervus elaphus elaphus) were infected experimentally with parelaphostrongylus tenuis in new brunswick, canada, and with elaphostrongylus cervi in new zealand. excretory-secretory (e-s) antigens from adult p. tenuis were evaluated for their serodiagnostic potential in identifying p. tenuis and heterologous e. cervi infections in a western blot. the antigen recognition profile of sera from animals infected with p. tenuis varied between individuals and with duration of infections, whereas ...200212099432
establishment of adult parelaphostrongylus tenuis, patent infections, and acquired immunity after experimental infection of white-tailed deer (odocoileus virginianus) and red deer (cervus elaphus elaphus).experimental parelaphostrongylus tenuis infections were established in white-tailed deer (odocoileus virginianus) and an atypical host, red deer (cervus elaphus elaphus). groups of deer were fed 10, 25, or 100 third-stage larvae (l3) of p. tenuis and received a single equivalent challenge exposure at varying intervals. infections were monitored up to 6 yr in white-tailed deer and up to 2.8 yr in red deer. the prepatent period in white-tailed deer varied from 91 to 1,072 days (381 +/- 374) and in ...200415165045
malignant melanoma in a captive red deer (cervus elaphus elaphus).we report a case of malignant melanoma in a captive red deer (cervus elaphus elaphus). the primary lesion was on the plantar aspect of the right pastern and infiltrated the surrounding skin, but not underlying tendons or bone. diffuse metastasis to the regional lymph nodes had occurred. histologically, lesions were characterized by large numbers of variably pigmented epithelioid cells with a high degree of nuclear atypia and many mitotic figures. this is the first reported case of this neoplasm ...200415650106
evidence for an increased geographical distribution of dermacentor reticulatus in germany and detection of rickettsia sp. rpa4.two studies were performed to elucidate the current distribution of the tick dermacentor reticulatus in germany. in the first one in 2003, a total of 365 dogs from 171 sites in the states of berlin and brandenburg was screened for ticks, and the corresponding outdoor sites that the dogs usually visited were searched for host-seeking ticks by the flagging method. a total of 1155 ticks was removed from the dogs. the majority were ixodes ricinus (88.5%), followed by d. reticulatus (9.1%) and i. hex ...200616524777
experimental transmission of bovine spongiform encephalopathy to european red deer (cervus elaphus elaphus).bovine spongiform encephalopathy (bse), a member of the transmissible spongiform encephalopathies (tse), primarily affects cattle. transmission is via concentrate feed rations contaminated with infected meat and bone meal (mbm). in addition to cattle, other food animal species are susceptible to bse and also pose a potential threat to human health as consumption of infected meat products is the cause of variant creutzfeldt-jakob disease in humans, which is invariably fatal. in the uk, farmed and ...200818507844
estimating the true prevalence of mycobacterium bovis in free-ranging elk in michigan.although relatively small, michigan's elk (cervus elaphus nelsoni) herd is highly valued by both hunters and the general public. elk and red deer (cervus elaphus elaphus) are highly susceptible to infection with mycobacterium bovis, the causative agent of bovine tuberculosis (tb), and outbreaks have been documented worldwide. the michigan elk range lies entirely within counties where tb is known to be enzootic in white-tailed deer (odocoileus virginianus). consequently, a project was undertaken ...200818957636
immunohistochemical and biochemical characteristics of bse and cwd in experimentally infected european red deer (cervus elaphus elaphus).the cause of the bovine spongiform encephalopathy (bse) epidemic in the united kingdom (uk) was the inclusion of contaminated meat and bone meal in the protein rations fed to cattle. those rations were not restricted to cattle but were also fed to other livestock including farmed and free living deer. although there are no reported cases to date of natural bse in european deer, bse has been shown to be naturally or experimentally transmissible to a wide range of different ungulate species. moreo ...200919635142
oral vaccination with microencapsuled strain 19 vaccine confers enhanced protection against brucella abortus strain 2308 challenge in red deer (cervus elaphus elaphus).bison (bison bison) and elk (cervus elaphus nelsoni) in the greater yellowstone area (gya), usa, are infected with brucella abortus, the causative agent of bovine brucellosis, and they serve as a wildlife reservoir for the disease. bovine brucellosis recently has been transmitted from infected elk to cattle in montana, wyoming, and idaho and has resulted in their loss of brucellosis-free status. an efficacious brucella vaccine with a delivery system suitable for wildlife would be a valuable tool ...200919901378
experimental oral transmission of chronic wasting disease to red deer (cervus elaphus elaphus): early detection and late stage distribution of protease-resistant prion protein.chronic wasting disease (cwd), an important emerging prion disease of cervids, is readily transmitted by intracerebral or oral inoculation from deer-to-deer and elk-to-elk, suggesting the latter is a natural route of exposure. studies of host range susceptibility to oral infection, particularly of those species found in habitats where cwd currently exists are imperative. this report describes the experimental transmission of cwd to red deer following oral inoculation with infectious cwd material ...201020436863
monitoring for bovine viral diarrhea virus in austrian red deer (cervus elaphus elaphus) by using ear-notch samples.during 2007-09, ear-notch samples from free-living (n=527) and farmed (n=237) austrian red deer (cervus elaphus elaphus) were tested for bovine viral diarrhea virus type 1 (bvdv-1) and type 2 (bvdv-2) by enzyme-linked immunosorbent assay and single-tube real-time reverse transcription pcr. ear-notch samples were collected by applying modified ear tags from randomly selected hunter-harvested red deer and from individuals originating from deer holdings. all samples tested negative for bvdv-1 and b ...201020966278
iron storage disease in red deer (cervus elaphus elaphus) is not associated with mutations in the hfe gene.iron storage diseases are rare conditions of dysregulated iron metabolism in man and animals. a genetic basis has been confirmed only for human haemochromatosis. iron storage disease was diagnosed in six related, 2-year-old male red deer of the same herd. these animals presented with weight loss and rough hair coats. haematological examination was unremarkable. at necropsy examination, gross lesions were restricted to cachexia. microscopical examination revealed severe, diffuse hepatocellular ne ...201121334004
surveillance of bovine tuberculosis and risk estimation of a future reservoir formation in wildlife in switzerland and liechtenstein.bovine tuberculosis (btb) caused by mycobacterium bovis or m. caprae has recently (re-) emerged in livestock and wildlife in all countries bordering switzerland (ch) and the principality of liechtenstein (fl). comprehensive data for swiss and liechtenstein wildlife are not available so far, although two native species, wild boar (sus scrofa) and red deer (cervus elaphus elaphus), act as btb reservoirs elsewhere in continental europe. our aims were (1) to assess the occurrence of btb in these wil ...201323349839
susceptibility of european red deer (cervus elaphus elaphus) to alimentary challenge with bovine spongiform encephalopathy.european red deer (cervus elaphus elaphus) are susceptible to the agent of bovine spongiform encephalopathy, one of the transmissible spongiform encephalopathies, when challenged intracerebrally but their susceptibility to alimentary challenge, the presumed natural route of transmission, is unknown. to determine this, eighteen deer were challenged via stomach tube with a large dose of the bovine spongiform encephalopathy agent and clinical signs, gross and histological lesions, presence and dist ...201525615837
genomic characterization of a novel epsilonpapillomavirus associated with pigmented papillomas in a red deer (cervus elaphus).two of a group of 15 farmed european red (cervus elaphus elaphus) x wapiti (c. e. canadensis) deer stags developed multiple persistent pigmented squamous papillomas (warts) on their chins. dna was extracted from a papilloma and a short section of dna from a novel papillomavirus (pv) was amplified. this short sequence was used to design 'outward facing' primers to amplify the remainder of the circular pv dna. the pcr product was sequenced using next-generation sequencing and the full genome of th ...201627154332
molecular characterization of fascioloides magna (trematoda: fasciolidae) from south-western poland based on mitochondrial markers.the giant liver fluke, fascioloides magna, is a veterinary important liver parasite of free living and domestic ruminants. this originally north american parasite was introduced along with its cervid hosts to europe where it has established three permanent natural foci - in northern italy, central and southern parts of the czech republic and the danube floodplain forests. the first record on fascioloidosis in poland originated from the lower silesian forest in south-western poland and since then ...201526204195
the origin of the giant liver fluke, fascioloides magna (trematoda: fasciolidae) from croatia determined by high-resolution melting screening of mitochondrial cox1 haplotypes.the high-resolution melting (hrm) method, recently optimized as a reliable technique for population study of the european fascioloides magna populations, was applied to determine an origin of f. magna individuals from croatia. the structure and frequency of mitochondrial cytochrome c oxidase subunit i (439 bp; cox1) haplotypes of 200 croatian flukes coming from 19 red deer (cervus elaphus elaphus) livers were screened and compared with recently determined reference samples of f. magna from all e ...201323609601
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