| divergent influenza-like viruses of amphibians and fish support an ancient evolutionary association. | influenza viruses (family orthomyxoviridae) infect a variety of vertebrates, including birds, humans, and other mammals. recent metatranscriptomic studies have uncovered divergent influenza viruses in amphibians, fish and jawless vertebrates, suggesting that these viruses may be widely distributed. we sought to identify additional vertebrate influenza-like viruses through the analysis of publicly available rna sequencing data. accordingly, by data mining, we identified the complete coding segmen ... | 2020 | 32962015 |
| multi-organ transcriptomic landscape of ambystoma velasci metamorphosis. | metamorphosis is a postembryonic developmental process that involves morphophysiological and behavioral changes, allowing organisms to adapt into a novel environment. in some amphibians, aquatic organisms undergo metamorphosis to adapt in a terrestrial environment. in this process, these organisms experience major changes in their circulatory, respiratory, digestive, excretory and reproductive systems. we performed a transcriptional global analysis of heart, lung and gills during diverse stages ... | 2020 | 32828730 |
| positive selection drives the evolution of a major histocompatibility complex gene in an endangered mexican salamander species complex. | immune gene evolution can be critical to species survival in the face of infectious disease. in particular, polymorphism in the genes of the major histocompatibility complex (mhc) helps vertebrates combat novel and diverse pathogens by increasing the number of pathogen-derived proteins that can initiate the host's acquired immune response. in this study, we used a combination of presumably adaptive and neutral markers to investigate mhc evolution in populations of five salamander species within ... | 2015 | 25846208 |