Publications

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mosquito host choices on livestock amplifiers of rift valley fever virus in kenya.animal hosts may vary in their attraction and acceptability as components of the host location process for assessing preference, and biting rates of vectors and risk of exposure to pathogens. however, these parameters remain poorly understood for mosquito vectors of the rift valley fever (rvf), an arboviral disease, and for a community of mosquitoes.201627036889
impact of housing condition on indoor-biting and indoor-resting anopheles arabiensis density in a highland area, central ethiopia.exposure of individuals to malaria infection may depend on their housing conditions as houses serve as biting and resting places of vectors. this study describes the association of housing conditions with densities of indoor-biting and indoor-resting anopheles arabiensis in hobe, dirama and wurib villages of a highland area in central ethiopia.201324191901
blood meal sources and entomological inoculation rates of anophelines along a highland altitudinal transect in south-central ethiopia.the role of anophelines in transmitting malaria depends on their distribution, preference to feed on humans and also their susceptibility to plasmodium gametocytes, all of which are affected by local environmental conditions. blood meal source and entomological inoculation rate of anophelines was assessed along a highland altitudinal transect in south- central ethiopia.201323433348
heterochromatin, histone modifications, and nuclear architecture in disease vectors.interactions between a pathogen and a vector are plastic and dynamic. such interactions can be more rapidly accommodated by epigenetic changes than by genetic mutations. gene expression can be affected by the proximity to the heterochromatin, by local histone modifications, and by the three-dimensional position within the nucleus. recent studies of disease vectors indicate that gene regulation by these factors can be important for susceptibility to pathogens, reproduction, immunity, development, ...026097808
a genome-scale investigation of incongruence in culicidae mosquitoes.comparison of individual gene trees in several recent phylogenomic studies from diverse lineages has revealed a surprising amount of topological conflict or incongruence, but we still know relatively little about its distribution across the tree of life. to further our understanding of incongruence, the factors that contribute to it and how it can be ameliorated, we examined its distribution in a clade of 20 culicidae mosquito species through the reconstruction and analysis of the phylogenetic h ...201526608059
age and prior blood feeding of anopheles gambiae influences their susceptibility and gene expression patterns to ivermectin-containing blood meals.ivermectin has been proposed as a novel malaria transmission control tool based on its insecticidal properties and unique route of acquisition through human blood. to maximize ivermectin's effect and identify potential resistance/tolerance mechanisms, it is important to understand its effect on mosquito physiology and potential to shift mosquito population age-structure. we therefore investigated ivermectin susceptibility and gene expression changes in several age groups of female anopheles gamb ...201526471037
malaria prevalence pattern observed in the highland fringe of butajira, southern ethiopia: a longitudinal study from parasitological and entomological survey.abstract: background: in ethiopia, information regarding highland malaria transmission is scarce, and no report has been presented from butajira highland so far whether the appearance of malaria in the area was due to endemicity or due to highland malaria transmission. thus this study aimed to determine the presence and magnitude of malaria transmission in butajira. methods: for parasitological survey, longitudinal study was conducted from october to december 2006. the entomological surveys were ...201121649923
variations in entomological indices in relation to weather patterns and malaria incidence in east african highlands: implications for epidemic prevention and control.malaria epidemics remain a significant public health issue in the east african highlands. the aim of this study was to monitor temporal variations in vector densities in relation to changes in meteorological factors and malaria incidence at four highland sites in kenya and uganda and to evaluate the implications of these relationships for epidemic prediction and control.200818983649
semipermeable species boundaries between anopheles gambiae and anopheles arabiensis: evidence from multilocus dna sequence variation.attempts to reconstruct the phylogenetic history of the anopheles gambiae cryptic species complex have yielded strongly conflicting results. in particular, an. gambiae, the primary african malaria vector, is variously placed as a sister taxon to either anopheles arabiensis or anopheles merus. the recent divergence times for members of this complex complicate phylogenetic analysis, making it difficult to unambiguously implicate interspecific gene flow, versus retained ancestral polymorphism, as t ...200312947038
distribution of the main malaria vectors in kenya.a detailed knowledge of the distribution of the main anopheles malaria vectors in kenya should guide national vector control strategies. however, contemporary spatial distributions of the locally dominant anopheles vectors including anopheles gambiae, anopheles arabiensis, anopheles merus, anopheles funestus, anopheles pharoensis and anopheles nili are lacking. the methods and approaches used to assemble contemporary available data on the present distribution of the dominant malaria vectors in k ...201020202199
a longitudinal study on anopheles mosquito larval abundance in distinct geographical and environmental settings in western kenya.abstract:201121477340
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