| [evaluation of the effect of calendula officinalis and echinacea angustifolia extracts of trichomonas vaginalis in vitro]. | | 1979 | 314706 |
| [pharmacology of calenduloside b, a new triterpene glycoside from the roots of calendula officinalis]. | calendulozide b--trioside of oleanolic acid, isolated from rhizomes of calendula officinalis, fam. compositae, used perorally in doses of 5, 10, 20 and 50 mg/kg exerted an antiulcerous action in 3 experimental ulcer models of different genesis (caffein-arsenic, butadion and induced by ligation of pylorus) and also displayed a certain antiphlogistic and sedative action. it did not have any effect on the cardiovascular system, the tone of intestinal smooth muscles, diuretic renal function and elec ... | 1978 | 700077 |
| antimutagenic activity of some saponins isolated from calendula officinalis l., c. arvensis l. and hedera helix l. | thirteen saponins were isolated and identified from calendula officinalis, c. arvensis and hedera helix. mutagenic and antimutagenic activities of these products were investigated using a modified liquid incubation technique of the salmonella/microsomal assay. the salmonella tester strain ta98 +/- s9 mix was used. screening of the antimutagenic activity was performed with a known promutagen: benzo-[a]pyrene (bap) and a mutagenic urine concentrate from a smoker (su). antimutagenic activities were ... | 1990 | 2204784 |
| [study of antiviral properties of calendula officinalis]. | | 1970 | 4318166 |
| influence of the physiological regeneration and epithelialization using fractions isolated from calendula officinalis. | standard skin wounds have been surgically induced in wistar albino rats. the wounds were covered with 5% unguentum containing fractions c1 and c5, isolated from the flowers of calendula officinalis belonging to fam. compositae, in combination with allantoin. epithelization has been determined in dynamics as a percentage compared with the beginning of the experiment, using the formula (formula: see text), where t is the wound surface in mm2 and n is the respective day after the beginning of the e ... | 1982 | 7185264 |
| [anti-inflammatory action of a group of plant extracts]. | use was made of wistar albino rats in which an inflammation was induced via the simultaneous injection of caraginan and prostaglandin e1 in order to evaluate the antiinflammatory activity of 6 freeze dried plant extracts. it was found that with such model of inflammation the inflammatory effect of caraginan was strongly enhanced, which was accompanied by the rapid and prolific white blood cell extravasates. the freeze-dried extracts of st. john's-wort (hypericum perforatum l.), potmarigold calen ... | 1981 | 7199215 |
| [uterotonic action of extracts from a group of medicinal plants]. | water extracts (infusions) from a group of medicinal plants were studied in terms of their activity enhancing the uterine tonus in a series of experiments with a preparation of an isolated rabbit and guinea pig uterine horn. in a final extract concentration of 1 to 2 mg crude drug per 1 cm3 the plants ranked in the following descending order with regard to their tonus-raising effect on the uterus: camomile (matricaria chamomilla l.), potmarigold calendula (calendula officinalis l.) cockscomb (ce ... | 1981 | 7314446 |
| the role of triterpenoids in the topical anti-inflammatory activity of calendula officinalis flowers. | by means of a bioassay-oriented fractionation of the co2 extract of calendula flowers, the triterpenoids are shown as the most important anti-inflammatory principles of the drug. among them, the faradiol monoester appears to be the most relevant principle for the activity of the drug, due to its quantitative prevalence. the unesterified faradiol, not present in the extract, is the most active of the tested compounds and equals indomethacin in activity, whereas the monools psi-taraxasterol, lupeo ... | 1994 | 7809203 |
| inhibitory activity of isorhamnetin glycosides from calendula officinalis l. on the activity of lipoxygenase. | | 1996 | 8720810 |
| triterpene alcohols from the flowers of compositae and their anti-inflammatory effects. | eleven tabular and nine ligulate flowers from 15 species of compositae plants were investigated for their triterpene alcohol constituents. this led to the isolation and identification of 11 triterpene alcohols as follows: heliaol, taraxasterol, psi-taraxasterol, alpha-amyrin, beta-amyrin, lupeol, taraxerol, cycloartenol, 24-methyl-enecycloartanol, tirucalla-7,24-dienol and dammaradienol. the tabular flowers of calendula officinalis, carthamus tinctorius, cosmos bipinnatus, chrysanthemum morifoli ... | 1996 | 8987908 |
| anti-hiv activity of extracts from calendula officinalis flowers. | extracts of dried flowers from calendula officinalis were examined for their ability to inhibit the human immunodeficiency virus type 1 (hiv-1) replication. both organic and aqueous extracts were relatively nontoxic to human lymphocytic molt-4 cells, but only the organic one exhibited potent anti-hiv activity in an in vitro mtt/tetrazolium-based assay. in addition, in the presence of the organic extract (500 micrograms/ml), the uninfected molt-4 cells were completely protected for up to 24 h fro ... | 1997 | 9207986 |
| anti-oedematous activities of the main triterpendiol esters of marigold (calendula officinalis l.). | separation and isolation of the genuine faradiol esters (1, 2) from flower heads of marigold (calendula (officinalis l., asteraceae) could be achieved by means of repeated column chromatography (cc) and hplc for the first time. structure elucidation of faradiol-3-myristic acid ester 1, faradiol-3-palmitic acid ester 2 and psi-taraxasterol 3 has been also performed, without any previous degradation by means of ms, 1h-nmr, 13c-nmr and 2d-nmr experiments. the anti-oedematous activities of these thr ... | 1997 | 9254116 |
| genotoxicity of an extract of calendula officinalis l. | a fluid extract of calendula officinalis l. displayed genotoxic properties when assayed for mitotic segregation in the heterozygous diploid d-30 of aspergillus nidulans. the extract of calendula exhibited dose-dependent toxicity and genotoxicity (both mitotic crossing-over and chromosome malsegregation being observed) to aspergillus in the range of five plate concentrations from 0.1 to 1.0 mg of solids/ml assayed. mutagenicity testing with the salmonella/microsome assay in strains ta 1535, ta 15 ... | 1998 | 9687081 |
| evidence for bioadhesive effects of polysaccharides and polysaccharide-containing herbs in an ex vivo bioadhesion assay on buccal membranes. | aqueous extracts of polysaccharide-containing plants are widely used in therapy for irritated mucus membranes in the pharynx region. in order to prove the existence of mucilaginous effects of polysaccharide hydrocolloids on epithelia an ex vivo system based on porcine buccal membranes was established. the tissue culture was stable and there was no indication of cytolytic processes during the 5 hour incubation period. this was confirmed through histological studies and the respective ldh values a ... | 2000 | 10705734 |
| evaluation of the immunomodulatory effects of five herbal plants. | a group of medicinal plants including, silybum marianum, matricaria chamomilla, calendula officinalis, cichorium intybus and dracocephalum kotschyi which grow in iran, were extracted with ethanol 70% and the mitogenic activity was examined both on human peripheral blood lymphocytes and thymocytes. effect of these extracts on proliferative responsiveness of human lymphocytes to phytohemagglutinin (pha) and on the mixed lymphocyte reaction (mlr) was also investigated. the results obtained indicate ... | 2000 | 10967468 |
| formation of conjugated delta8,delta10-double bonds by delta12-oleic-acid desaturase-related enzymes: biosynthetic origin of calendic acid. | divergent forms of the plant delta(12)-oleic-acid desaturase (fad2) have previously been shown to catalyze the formation of acetylenic bonds, epoxy groups, and conjugated delta(11),delta(13)-double bonds by modification of an existing delta(12)-double bond in c(18) fatty acids. here, we report a class of fad2-related enzymes that modifies a delta(9)-double bond to produce the conjugated trans-delta(8),trans-delta(10)-double bonds found in calendic acid (18:3delta(8trans,10trans,12cis)), the majo ... | 2001 | 11067856 |
| identification and analysis of a gene from calendula officinalis encoding a fatty acid conjugase. | two homologous cdnas, cofad2 and cofac2, were isolated from a calendula officinalis developing seed by a polymerase chain reaction-based cloning strategy. both sequences share similarity to fad2 desaturases and fad2-related enzymes. in c. officinalis plants cofad2 was expressed in all tissues tested, whereas cofac2 expression was specific to developing seeds. expression of cofad2 cdna in yeast (saccharomyces cerevisiae) indicated it encodes a delta12 desaturase that introduces a double bond at t ... | 2001 | 11161042 |
| [activity of cytoplasmic proteinases from rat liver in heren's carcinoma during tumor growth and treatment with medicinal herbs]. | the dynamics of the acid and neutral proteinases general enzymes activity change in the hepatocytes postnuclear fraction in the rats suffering from the heren's carcinoma was investigated. it was determined that in the tumor development of the enzyme activity level of both the acid and neutral proteinases increased 2,6-fold. the natural preparation of the herbs (calendula officinalis l., echinacea purpurea l., scorzonera humilis l., aconitum moldavicum hacq.) normalizes both the activity of the i ... | 2000 | 11200483 |
| cytotoxic effect of conjugated trienoic fatty acids on mouse tumor and human monocytic leukemia cells. | the cytotoxicity of fatty acids from seed oils containing conjugated linolenic acids (cln) was studied. fatty acids from pomegranate, tung, and catalpa were cytotoxic to human monocytic leukemia cells at concentrations exceeding 5 microm for pomegranate and tung and 10 microm for catalpa, but fatty acids from pot marigold oil had no effect at concentrations ranging up to 163 microm. the main conjugated fatty acids of pomegranate, tung, catalpa, and pot marigold were cis(c)9,trans(t)11,c13-cln (7 ... | 2001 | 11432460 |
| medicinal flowers. iii. marigold. (1): hypoglycemic, gastric emptying inhibitory, and gastroprotective principles and new oleanane-type triterpene oligoglycosides, calendasaponins a, b, c, and d, from egyptian calendula officinalis. | the methanolic extract and its 1-butanol-soluble fraction from the flowers of calendula officinalis were found to show a hypoglycemic effect, inhibitory activity of gastric emptying, and gastroprotective effect. from the 1-butanol-soluble fraction, four new triterpene oligoglycosides, calendasaponins a, b, c, and d, were isolated, together with eight known saponins, seven known flavonol glycosides, and a known sesquiterpene glucoside. their structures were elucidated on the basis of chemical and ... | 2001 | 11456093 |
| final report on the safety assessment of calendula officinalis extract and calendula officinalis. | calendula officinalis extract is an extract of the flowers of calendula officinalis, the common marigold, whereas calendula officinalis is described as plant material derived from the flowers of c. officinalis. techniques for preparing calendula officinalis extract include gentle disintegration in soybean oil. propylene glycol and butylene glycol extractions were also reported. components of these ingredients are variously reported to include sugars, carotenoids, phenolic acids, sterols, saponin ... | 2001 | 11558637 |
| genotoxic and anti-genotoxic properties of calendula officinalis extracts in rat liver cell cultures treated with diethylnitrosamine. | calendula officinalis flower extracts are used to cure inflammatory and infectious diseases, for wound healing and even cancer with partial objective evidence of its therapeutic properties or toxic effects, many of which can be attributed to the presence of flavonols. we studied whether c. officinalis extracts induce unscheduled dna synthesis (uds) in rat liver cell cultures, and if these extracts can reverse diethylnitrosamine (den)-induced uds. four different flower extracts were prepared: aqu ... | 2002 | 12020598 |
| protective properties of butanolic extract of the calendula officinalis l. (marigold) against lipid peroxidation of rat liver microsomes and action as free radical scavenger. | calendula officinalis (marigold) has many pharmacological properties. it is used for the treatment of skin disorders, pain and also as a bactericide, antiseptic and anti-inflammatory. reactive oxygen species (ros) and reactive nitrogen species (rns) are known to participate in the pathogenesis of various human diseases and may be involved in the conditions which c. officinalis is used to treat. the aim of this study was to investigate the relationship between the beneficial properties of this pl ... | 2002 | 12189055 |
| in vitro anti-hepatoma activity of fifteen natural medicines from canada. | fifteen crude drugs, stellaria media cyrill. (caryophyllaceae), calendula officinalis l. (compositae), achillea millefolium l. (compositae), verbascum thapsus l. (scrophulariaceae), plantago major l. (plantaginaceae), borago officinalis l. (boraginaceae), satureja hortensis l. (labiatae), coptis groenlandica salisb. (ranunculaceae), cassia angustifolia vahl. (leguminosae), origanum majorana l. (labiatae), centella asiatica l. (umbelliferae), caulophyllum thalictroides mich. (berberidaceae), pice ... | 2002 | 12203264 |
| mechanism of 1,4-dehydrogenation catalyzed by a fatty acid (1,4)-desaturase of calendula officinalis. | the mechanism by which the fatty acid (1,4)-desaturase of calendula officinalis produces calendic acid from linoleic acid has been probed through the use of kinetic isotope effect (kie) measurements. this was accomplished by incubating appropriate mixtures of linoleate and regiospecifically dideuterated isotopomers with a strain of saccharomyces cerevisiae expressing a functional (1,4)-desaturase. gc-ms analysis of methyl calendate obtained in these experiments showed that the oxidation of linol ... | 2002 | 12383261 |
| antibacterial activity of medicinal plant extracts against periodontopathic bacteria. | this study was performed to evaluate the antibacterial activity of althaea officinalis l. roots, arnica montana l. flowers, calendula officinalis l. flowers, hamamelis virginiana l. leaves, illicium verum hook. fruits and melissa officinalis l. leaves, against anaerobic and facultative aerobic periodontal bacteria: porphyromonas gingivalis, prevotella spp., fusobacterium nucleatum, capnocytophaga gingivalis, veilonella parvula, eikenella corrodens, peptostreptococcus micros and actinomyces odont ... | 2003 | 12820224 |
| on the sedative and hypotensive effect of preparations from the plant calendula officinalis. | | 1964 | 14221993 |
| phase iii randomized trial of calendula officinalis compared with trolamine for the prevention of acute dermatitis during irradiation for breast cancer. | the effectiveness of nonsteroid topical agents for the prevention of acute dermatitis during adjuvant radiotherapy for breast carcinoma has not been demonstrated. the goal of this study was to compare the effectiveness of calendula (pommade au calendula par digestion; boiron ltd, levallois-perret, france) with that of trolamine (biafine; genmedix ltd, france), which is considered in many institutions to be the reference topical agent. | 2004 | 15084618 |
| evaluation of homeopathy in broiler chickens exposed to live viral vaccines and administered calendula officinalis extract. | in this study it was determined that a calendula officinalis water extract can reduce the immune response to three different viruses in broiler chickens, associated with improvement in body weights. | 2004 | 15277989 |
| antioxidative responses of calendula officinalis under salinity conditions. | to gain a better insight into long-term salt-induced oxidative stress, some physiological parameters in marigold (calendula officinalis l.) under 0, 50 and 100 mm nacl were investigated. salinity affected most of the considered parameters. high salinity caused reduction in growth parameters, lipid peroxidation and hydrogen peroxide accumulation. under high salinity stress, a decrease in total glutathione and an increase in total ascorbate (asa + dha), accompanied with enhanced glutathione reduct ... | 2004 | 15474374 |
| cytotoxicity and gene induction by some essential oils in the yeast saccharomyces cerevisiae. | in order to get an insight into the possible genotoxicity of essential oils (eos) used in traditional pharmacological applications we tested five different oils extracted from the medicinal plants origanum compactum, coriandrum sativum, artemisia herba alba, cinnamomum camphora (ravintsara aromatica) and helichrysum italicum (calendula officinalis) for genotoxic effects using the yeast saccharomyces cerevisiae. clear cytotoxic effects were observed in the diploid yeast strain d7, with the cells ... | 2005 | 15975845 |
| antioxidant properties of some hydroalcoholic plant extracts with antiinflammatory activity. | the hydroalcoholic extracts of calendula officinalis, hypericum perforatum, plantago lanceolata and glycyrrhiza glabra which exhibited different anti-inflammatory activities were evaluated for the possible mode of action by studying their antioxidant potential. in the present study we investigated if standardized hydroalcoholic extracts of plants such as calendula officinalis, hypericum perforatum, plantago lanceolata and glycyrrhiza glabra produced by hofigal stock company could modulate the re ... | 2003 | 16008145 |
| investigation of genotoxic and antigenotoxic activities of melampodium divaricatum in salmonella typhimurium. | melampodium divaricatum is a member of the asteraceae and in brazil is known as false-calendula, its flowers being used in anti-inflammatory preparations, substituting the true calendula or marigold (calendula officinalis l.). the flower extract was investigated for mutagenic and antimutagenic effect in the salmonella/microsome assay. the tested extract was not mutagenic in the strains ta100, ta98, ta97a and ta102 and decreased the mutagenicity of aflatoxin b1, benzo(a)pyrene and daunomycin. chl ... | 2006 | 16182509 |
| the hepatoprotective action of ten herbal extracts in ccl4 intoxicated liver. | the effect of ten phytotherapeutic products on ccl(4) intoxicated liver in albino male wistar rats was investigated. biochemical parameters, including serum transaminase activity (gpt and got), histoenzymological measurements (lactate dehydrogenase, ldh; succinate dehydrogenase, sdh, cytochromoxidase, cyox; mg(2+)-dependent adenosine triphosphatase, atp-ase) and histochemical (sudan black) and histological examinations (haematoxylin-eosin staining) of the liver were investigated. some positive e ... | 2005 | 16220565 |
| a clinical study: melaleuca, manuka, calendula and green tea mouth rinse. | a novel mouthrinse (ind 61,164) containing essential oils and extracts from four plant species (melaleuca alternifolia, leptospermum scoparium, calendula officinalis and camellia sinensis) were tested. this study aimed to evaluate the safety, palatability and preliminary efficacy of the rinse. fifteen subjects completed the phase i safety study. seventeen subjects completed the phase ii randomized placebo-controlled study. plaque was collected, gingival and plaque indices were recorded (baseline ... | 2005 | 16317652 |
| a dual and opposite effect of calendula officinalis flower extract: chemoprotector and promoter in a rat hepatocarcinogenesis model. | calendula officinalis extracts have protective and cytotoxic effects. we previously reported the dual activity of c. officinalis in primary rat hepatocyte cultures treated with n-nitrosodiethylamine. at nm concentrations it was anti-genotoxic while at microm concentrations it exhibited genotoxic effects. here we tested the activity of calendula officinalis in vivo in male fischer 344 rats initiated with n-nitrosodiethylamine, promoted with 2-acetylaminofluorene, and 70 % partially hepatectomized ... | 2006 | 16534725 |
| a new extract of the plant calendula officinalis produces a dual in vitro effect: cytotoxic anti-tumor activity and lymphocyte activation. | phytopharmacological studies of different calendula extracts have shown anti-inflammatory, anti-viral and anti-genotoxic properties of therapeutic interest. in this study, we evaluated the in vitro cytotoxic anti-tumor and immunomodulatory activities and in vivo anti-tumor effect of laser activated calendula extract (lace), a novel extract of the plant calendula officinalis (asteraceae). | 2006 | 16677386 |
| studies on spasmogenic and spasmolytic activities of calendula officinalis flowers. | the aqueous-ethanol extract of calendula officinalis flowers (co.cr) was studied for its possible spasmolytic and spasmogenic effects in isolated gut preparations. in rabbit jejunum, co.cr caused a dose-dependent (0.03-3.0 mg/ml) relaxation of spontaneous and k+-induced contractions, suggestive of calcium channel blockade (ccb). in a few preparations, a mild non-reproducible spasmogenic effect was observed at lower doses, followed by relaxation. the ccb effect was confirmed when pretreatment of ... | 2006 | 16906636 |
| anti-inflammatory, anti-tumor-promoting, and cytotoxic activities of constituents of marigold (calendula officinalis) flowers. | ten oleanane-type triterpene glycosides, 1-10, including four new compounds, calendulaglycoside a 6'-o-methyl ester (2), calendulaglycoside a 6'-o-n-butyl ester (3), calendulaglycoside b 6'-o-n-butyl ester (5), and calendulaglycoside c 6'-o-n-butyl ester (8), along with five known flavonol glycosides, 11-15, were isolated from the flowers of marigold (calendula officinalis). upon evaluation of compounds 1-9 for inhibitory activity against 12-o-tetradecanoylphorbol-13-acetate (tpa)-induced inflam ... | 2006 | 17190444 |
| improved anti-inflammatory activity of three new terpenoids derived, by systematic chemical modifications, from the abundant triterpenes of the flowery plant calendula officinalis. | rings a, d and e of faradiol (1), and ring e of both arnidiol (10) and calenduladiol (4) have been subjected to various selective chemical manipulations to modify polarity, water affinity, h-bonding, sterics, and number of aromatic groups of these anti-inflammatory natural compounds. a total of 15 new and four known pentacyclic triterpenoids have been obtained in this way. some 13 terpenoids were evaluated for their topical anti-inflammatory activities with respect to inhibition of croton oil in ... | 2005 | 17192009 |
| toxicological studies on hydroalcohol extract of calendula officinalis l. | the hydroalcohol extract (hae) of calendula officinalis l. was evaluated for its acute toxicity by the oral route in rats and mice and for the subacute effect on hematological, biochemical and morphologic parameters in rats. in the acute toxicity test, hae failed to cause death in the animals after administration of oral doses up to 5.0 g/kg. oral treatment with hae at 0.025, 0.25, 0.5 and 1.0 g/kg did not induce hematological alterations when compared with the control group. in the biochemical ... | 2007 | 17221830 |
| ethnoveterinary medicines used for ruminants in british columbia, canada. | the use of medicinal plants is an option for livestock farmers who are not allowed to use allopathic drugs under certified organic programs or cannot afford to use allopathic drugs for minor health problems of livestock. | 2007 | 17324258 |
| the evaluation of trifloxystrobin in protection of calendula officinalis (pot marigold) against erysiphe cichoracearum dc. | the aim of the two-years field's examinations was the evaluation of the fungicide zato 50 wg (biologically active substances bas--trifloxystrobin 50%) in protection of calendula officinalis (pot marigold) against erysiphe cichoracearum. mentioned fungicide was applied at three concentrations: 0.1, 0.15 and 0.2%. as the standard fungicide amistar 250 sc (biologically active substances bas - azoxystrobin 250 g/dm3) was used. in every year of research work the four protective treatments were carrie ... | 2006 | 17390856 |
| ethnoveterinary medicines used to treat endoparasites and stomach problems in pigs and pets in british columbia, canada. | this paper documents the medicinal plants used to treat endoparasites and stomach problems in dogs, cats and pigs in british columbia, canada. ethnoveterinary data was collected over a 6-month period in 2003. the majority of the information on pets came from 2 naturopaths, 10 herbalists, 5 dog trainers, breeders and pet shop owners, 9 holistic veterinarians and 6 of 27 organic farmers. two pig farmers joined the study in the final stages. the following plants were used as anthelmintics: artemisi ... | 2007 | 17628343 |
| [entrapment of herbal extracts in biodegradable microcapsules]. | the microcapsules with entrapped herbal water-soluble extracts plantago major and calendula officinalis l. (he) were prepared by lbl-adsorption of carrageenan and modificated chitosan onto caco3 microparticles with their subsequent dissolving after the treatment of edta. entrapment of he was performed by adsorption and co-precipitation techniques. the co-precipitation provided better entrapment of he compared to adsorption. in vitro release kinetics in an artificial gastric juice (agj) was studi ... | 2007 | 18323151 |
| medicinal plant treatments for fleas and ear problems of cats and dogs in british columbia, canada. | research conducted in 2003/2004 documented and validated (in a non-experimental way) ethnoveterinary medicines used by small-scale, organic livestock farmers in british columbia (bc), canada. interviews were conducted with 60 participants who were organic farmers or holistic medicinal/veterinary practitioners. a workshop was held with selected participants to discuss the plant-based treatments. this paper reports on the medicinal plants used for fleas in cats and dogs. fleas and flies are treate ... | 2008 | 18563443 |
| the comparison of in vivo antigenotoxic and antioxidative capacity of two propylene glycol extracts of calendula officinalis (marigold) and vitamin e in young growing pigs. | the objective of the study was to evaluate the protective effect of calendula officinalis propylene glycol extracts against oxidative dna damage and lipid peroxidation induced by high polyunsaturated fatty acid (pufa) intake in young growing pigs. forty young growing pigs were assigned to five treatment groups: control; oil (linseed oil supplementation); c. officinalis 1 and 2 groups (linseed oil plus 3 ml/day of c. officinalis propylene glycol extracts); and vitamin e group (linseed oil plus 10 ... | 2009 | 18700847 |
| effect of calendula officinalis flower extract on acute phase proteins, antioxidant defense mechanism and granuloma formation during thermal burns. | effect of calendula officinalis flower extract was investigated against experimentally induced thermal burns in rats. burn injury was made on the shaven back of the rats under anesthesia and the animals were treated orally with different doses of the flower extract (20 mg, 100 mg and 200 mg/kg body weight). the animals treated with the extract showed significant improvement in healing when compared with the control untreated animals. the indicators of the wound healing such as collagen-hydroxypr ... | 2008 | 18818737 |
| use of heteroduplex mobility assay for identification and differentiation of phytoplasmas in the aster yellows group and the clover proliferation group. | abstract this paper describes the identification and differentiation of phytoplasmas by a highly sensitive diagnostic technique, dna heteroduplex mobility assay (hma). closely related phytoplasma isolates of clover proliferation (cp), potato witches'-broom (pwb), and alfalfa witches'-broom (awb) were collected from the field from 1990 to 1999. the entire 16s rrna gene and 16/23s spacer region were amplified by polymerase chain reaction (pcr) from the field samples and standard cp, pwb, and awb p ... | 2001 | 18943942 |
| antibacterial and antiparasitic activity of oleanolic acid and its glycosides isolated from marigold (calendula officinalis). | the antibacterial and antiparasitic activities of free oleanolic acid and its glucosides and glucuronides isolated from marigold (calendula officinalis) were investigated. the mic of oleanolic acid and the effect on bacterial growth were estimated by a600 measurements. oleanolic acid's influence on bacterial survival and the ability to induce autolysis were measured by counting the number of cfu. cell morphology and the presence of endospores were observed under electron and light microscopy, re ... | 2008 | 18951335 |
| reproductive assessment of hydroalcohol extract of calendula officinalis l. in wistar rats. | the present study was conducted to evaluate the effects of the administration of a hydroalcohol extract of calendula officinalis l. flowers (hae) on the reproductive function of wistar rats. four groups of adult male rats were treated orally with hae at doses of 0, 0.25, 0.5 and 1.0 g/kg for 60 consecutive days. from day 53 to 60 of treatment, rats were mated with untreated and fertile female rats. reproductive parameters including testicular morphology, reproductive organ weights, fertility ind ... | 2009 | 19288530 |
| anti-inflammatory activity of flower extract of calendula officinalis linn. and its possible mechanism of action. | calendula officinalis flower extract possessed significant anti-inflammatory activity against carrageenan and dextran-induced acute paw edema. oral administration of 250 and 500 mg/kg body weight calendula extract produced significant inhibition (50.6 and 65.9% respectively) in paw edema of animals induced by carrageenan and 41.9 and 42.4% respectively with inflammation produced by dextran. in chronic anti-inflammatory model using formalin, administration of 250 and 500 mg/kg body weight calendu ... | 2009 | 19374166 |
| hepato and reno protective action of calendula officinalis l. flower extract. | flower extract of c. officinalis l. was evaluated for its protective effect against ccl4 induced acute hepatotoxicity and cisplatin induced nephrotoxicity. the activities of serum marker enzymes of liver injury like glutamate pyruvate transaminase (sgpt), glutamate oxaloacetate transaminase (sgot) and alkaline phosphatase (alp) which were increased by ccl4 injection was found to be significantly reduced by the pretreatment of the flower extract at 100 and 250 mg/kg body weight. the lipid peroxid ... | 2009 | 19405380 |
| antioxidant activity of calendula officinalis extract: inhibitory effects on chemiluminescence of human neutrophil bursts and electron paramagnetic resonance spectroscopy. | there is growing interest in natural chemical compounds from aromatic, spicy, medicinal and other plants with antioxidant properties in order to find new sources of compounds inactivating free radicals generated by metabolic pathways within body tissue and cells, mainly polymorphonuclear leukocytes (pmns) whose overregulated recruitment and activation generate a large amount of reactive oxygen species (ros) and reactive nitrogen species (rns), leading to an imbalance of redox homeostasis and oxi ... | 2009 | 19420983 |
| wound healing activity of flower extract of calendula officinalis. | the effects of oral and topical application of calendula officinalis flower extract on excision wounds made in rats were checked. the parameters assessed were the days needed for re-epithelization and percentage of wound closure. the hydroxy proline and hexosamine content in the granuloma tissue of the wound was also measured. the percentage of wound closure was 90.0% in the extract-treated group, whereas the control group showed only 51.1% on the eighth day of wounding (p < .01). the days neede ... | 2009 | 19601397 |
| investigations into the antibacterial activities of phytotherapeutics against helicobacter pylori and campylobacter jejuni. | the prevalence of gastric diseases is increasing with h. pylori, the causative agent of acute and chronic gastritis, being a major predisposing factor for peptic ulcer disease and gastric carcinoma. c. jejuni is the most common cause of enteric infections, particularly among children, resulting in severe diarrhoea. increasing drug resistance of these bacteria against standard antibiotics, and the more widespread use of herbal medicines, favours investigations into additional anti-helicobacter an ... | 2010 | 19653313 |
| determination of the wound healing effect of calendula extracts using the scratch assay with 3t3 fibroblasts. | pharmacological relevance: presentation of the scratch assay as a convenient and inexpensive in vitro tool to gain first insights in the wound healing potential of plant extracts and natural compounds. | 2009 | 19781615 |
| hyperbranched polyglycerol electrospun nanofibers for wound dressing applications. | this study reports on the performance of electrospun hyperbranched polyglycerol nanofibers capable of providing an active agent delivery for wound dressing applications. the aim of this work was to prepare electrospun hpgl nanofibers containing calendula officinalis as a wound-healing and anti-inflammatory agent. the morphology of the electrospun hpgl-c. officinalis nanofibers was analyzed using a scanning electron microscope. the results showed that the diameters of the fibers were in nanoscale ... | 2010 | 19788943 |
| [biodegradable polymer microparticles with entraped herbal extracts: preparation with supercritical carbon dioxide and use for tissue repair]. | biodegradable microparticles based on poly-d,l-lactide with entrapped mixture of herbal water-soluble extracts of plantago major and calendula officinalis were prepared. for preparation of these microparticles the previously developed method based on the usage of supercritical carbon dioxide (sc-co2) was proposed. microparticles were obtained by two techniques: 1) by preparing porous polymer monolith containing entrapped mixture of herbal extracts, which was then reduced to fine microparticles ( ... | 2009 | 20000125 |
| [new promising natural immunocorrective agents]. | the influence of sorbus sibirica, calendula officinalis and althaea officinalis extracts on the humoral immune response and nonspecific resistance of mice to immunosuppression by cyclophosphan was studied. it was shown that these extracts are not inferior to echinacea purpurea tincture in terms of stimulation of humoral immune response, phagocytic and bactericidal activity of peritoneal macrophages but exceed effect of e. purpurea on phagocytic activity of peripheral blood neutrophils. | 2009 | 20017400 |
| protective effect of calendula officinalis extract against uvb-induced oxidative stress in skin: evaluation of reduced glutathione levels and matrix metalloproteinase secretion. | calendula officinalis flowers have long been employed time in folk therapy, and more than 35 properties have been attributed to decoctions and tinctures from the flowers. the main uses are as remedies for burns (including sunburns), bruises and cutaneous and internal inflammatory diseases of several origins. the recommended doses are a function both of the type and severity of the condition to be treated and the individual condition of each patient. therefore, the present study investigated the ... | 2010 | 20026397 |
| topical calendula officinalis l. successfully treated exfoliative cheilitis: a case report. | authors describe a case of recurrent exfoliative cheilitis that responded to treatment with a standardized topical preparation of calendula officinalis l. an eighteen-year-old man was referred to unesp - são paulo state university, department of biosciences and oral diagnosis, são josé dos campos dental school to investigate a chronic dry scaling lesion on his lips. the patient's main chief was aesthetic compromising. corticoid therapy was suspended and calendula officinalis ointment 10% for ad ... | 2009 | 20062714 |
| comparative assessment of total phenolic content in selected medicinal plants. | this study was to compare the total phenolic (tp) content in extracts from eleven plant materials collected at different geographical locations in kenya, nigeria, and usa. these plants have been selected because the majority of them are highly pigmented, from yellow to purple, and would therefore have economic value in industries for producing antioxidants and surfactants. two of them were collected from the industrial and domestic waste outlets. each analysis was achieved using the folin-ciocal ... | 2008 | 20119491 |
| acute and subchronic oral toxicities of calendula officinalis extract in wistar rats. | we have studied the acute and subchronic oral toxicities of calendula officinalis extract in male and female wistar rats. a single acute c. officinalis extract dose of 2000 mg/kg dissolved in distilled water was administered by oral gavage for acute toxicity. subchronic doses of 50, 250 and 1000 mg/kg/day were administered in drinking water. the major toxicological endpoints examined included animal body weight, water and food intake, selected tissue weights, and histopathological examinations. ... | 2011 | 20335011 |
| heparin-binding epidermal growth factor expression in kato-iii cells after helicobacter pylori stimulation under the influence of strychnos nux vomica and calendula officinalis. | previous studies have shown the stimulating effect of helicobacter pylori on the gene expression of heparin-binding epidermal growth factor (hb-egf) using the gastric epithelial cell line kato-iii. strychnos nux vomica (nux vomica) and calendula officinalis are used in highly diluted form in homeopathic medicine to treat patients suffering from gastritis and gastric ulcers. | 2010 | 20674841 |
| [effect of plant polysaccharides on th1-dependent immune response: screening investigation]. | we have studied the influence of water-soluble polysaccharides isolated from tussilago farfara l. leaves, betula verrucosa ehrh. leaves, calendula officinalis l. flowers, acorus calamus rhizomes, inula helenium l. rhizomes, overground part of trifolium pretense l., and overground part ofartemisia absinthium l., on thl immune response induced by sheep red blood cells and on no production by murine peritoneal macrophages in vitro. all the investigated polysaccharides have stimulated a th1 response ... | 2010 | 20726346 |
| amelioration of myocardial ischemic reperfusion injury with calendula officinalis. | calendula officinalis of family asteraceae, also known as marigold, has been widely used from time immemorial in indian and arabic cultures as an anti-inflammatory agent to treat minor skin wound and infections, burns, bee stings, sunburn and cancer. at a relatively high dose, calendula can lower blood pressure and cholesterol. since inflammatory responses are behind many cardiac diseases, we sought to evaluate if calendula could be cardioprotective against ischemic heart disease two groups of h ... | 2010 | 20874690 |
| development and in vitro evaluation of biopolymers as a delivery system against periodontopathogen microorganisms. | periodontal disease is the major cause of tooth loss in adults. porphyromonas gingivalis and aggregatibacter actinomycetemcomitans are considered key pathogens in periodontitis. the treatment consists of oral hygiene education, instrumentation for removal of calculus (scaling), chemotherapy and periodontal surgery. several agents are commercially available; these chemicals can alter oral microbiota and have undesirable side-effects such as vomiting, diarrhea and tooth staining. hence, the search ... | 2010 | 21053691 |
| [selection of winter plant species for wetlands constructed as sewage treatment systems and evaluation of their wastewater purification potentials]. | in order to establish an evaluation system for selection of winter wetland plants possessing high wastewater purification potentials in subtropics areas, designed sewage treatment experiments were carried out by introducing into the constructed wetlands 25 species of winter wetland plants. cluster analysis was performed by including harmful environment-resistant enzyme and substrate enzyme activities into the commonly applied plant screening and assessment indexes system. the obtained results in ... | 2010 | 21090294 |
| angiogenic activity of calendula officinalis flowers l. in rats. | in this work, angiogenic activity of calendula officinalis l. (asteraceae) ethanolic extract and dichloromethane and hexanic fractions were evaluated, considering medicinal properties, especially healing activity, are attributed to this plant. | 2011 | 21271199 |
| inhibition of metastasis of b16f-10 melanoma cells in c57bl/6 mice by an extract of calendula officinalis l flowers. | to determine the effect of a calendula officinalis flower extract on lung metastasis by b16f-10 melanoma cells in c57bl/6 mice. | 2010 | 21338232 |
| triterpenoid saponins affect the function of p-glycoprotein and reduce the survival of the free-living stages of heligmosomoides bakeri. | we studied the effect of triterpenoid saponins on the development of free-living stages of heligmosomoides bakeri, a parasitic nematode of the mouse intestine. we evaluated the effectiveness of oleane-type glucuronides (glcuaoa) isolated from calendula officinalis and beta vulgaris. the rhodamine 123 retention assay was used to detect dysfunctions of the major membrane transporter for xenobiotics, p-glycoprotein (pgp). both c. officinals and b. vulgaris glcuaoa affect the development of the free ... | 2011 | 21376470 |
| efficacy of marigold extract-loaded formulations against uv-induced oxidative stress. | the present study investigated the potential use of topical formulations containing marigold extract (me) (calendula officinalis extract) against ultraviolet (uv)b irradiation-induced skin damage. the physical and functional stabilities, as well as the skin penetration capacity, of the different topical formulations developed were evaluated. in addition, the in vivo capacity to prevent/treat the uvb irradiation-induced skin damage, in hairless mice, of the formulation with better skin penetratio ... | 2011 | 21491442 |
| subacute effect of cigarette smoke exposure in rats: protection by pot marigold (calendula officinalis l.) extract. | this study was carried out to determine the preventive effect of calendula officinalis l. (pot marigold) on rats exposed to cigarette smoke (cs). rats were divided into three groups as control, cs and cs + pot marigold (pm). the rats in the cs and cs + pm groups were subjected to cs for 1 h twice a day for 23 days. pm (100 mg/kg body weight) was given to rats in the cs + pm group by gavage, 1 h before each administration period. while malondialdehyde, protein carbonyl contents and reduced glutat ... | 2011 | 21505008 |
| antimicrobial activity of calendula officinalis, camellia sinensis and chlorhexidine against the adherence of microorganisms to sutures after extraction of unerupted third molars. | the objective of this study was to compare the antimicrobial effect of mouthwashes containing calendula officinalis l., camellia sinensis (l.) kuntze and 0.12% chlorhexidine digluconate on the adherence of microorganisms to suture materials after extraction of unerupted third molars. | 2011 | 21986652 |
| Calendula extract: effects on mechanical parameters of human skin. | The aim of this study was to evaluate the effects of newly formulated topical cream of Calendula officinalis extract on the mechanical parameters of the skin by using the cutometer. The Cutometer 580 MPA is a device that is designed to measure the mechanical properties of the skin in response to the application of negative pressure. This non-invasive method can be useful for objective and quantitative investigation of age related changes in skin, skin elasticity, skin fatigue, skin hydration, an ... | 2011 | 21928714 |
| new experimental hosts of tobacco streak virus and absence of true seed transmission in leguminous hosts. | of 70 plant species tested, 50 species were susceptible to tobacco streak virus (tsv) on sap inoculation. both localized (necrotic and chlorotic spots) and systemic (necrotic spots, axillary shoot proliferation, stunting, total necrosis and wilt) symptoms are observed by majority of plant species. eleven new experimental hosts were identified viz., amaranthus blitum var. oleracea (chaulai sag), celosia cristata (cocks comb), beta vulgaris var. bengalensis (palak/indian spinach), calendula offici ... | 2011 | 23637490 |
| distribution of oleanolic acid glycosides in vacuoles and cell walls isolated from protoplasts and cells of calendula officinalis leaves. | the contents of oleanolic acid and its 3-0-glucuronide derivatives as well as of 3-0-glucoside derivatives were determined in vacuoles prepared from protoplasts and cell walls obtained from cells of calendula officinalis leaves. in both cell compartments studied 37% of total cellular oleanolic acid were accumulated, 0.6% occurring as free oleanolic acid (only in vacuoles). glucuronides accounted for 31.1% (20.7% in vacuoles and 10.4% in cell walls), and glucosides for 5.3% (2.6% in vacuoles and ... | 2009 | 2799856 |
| of glycosides of oleanolic acid from shoot to root in calendula officinalis. | | 2014 | 4446886 |
| the microbiome of medicinal plants: diversity and importance for plant growth, quality and health. | past medicinal plant research primarily focused on bioactive phytochemicals, however, the focus is currently shifting due to the recognition that a significant number of phytotherapeutic compounds are actually produced by associated microbes or through interaction with their host. medicinal plants provide an enormous bioresource of potential use in modern medicine and agriculture, yet their microbiome is largely unknown. the objective of this review is (i) to introduce novel insights into the pl ... | 2013 | 24391634 |
| comparison of antimicrobial activity of essential oils, plant extracts and methylparaben in cosmetic emulsions: 2 months study. | the aim of the study was to compare the preservative effectiveness of plant extracts (matricaria chamomilla, aloe vera, calendula officinalis) and essential oils (lavandulla officinalis, melaleuca alternifolia, cinnamomum zeylanicum) with methylparaben in cosmetic emulsions against skin microflora during 2 months of application by volunteers. cosmetic emulsions with extracts (2.5 %), essential oils (2.5 %), methylparaben (0.4 %) or placebo were tested by 40 volunteers during 2 months of treatmen ... | 2014 | 24891745 |
| a review on phytochemistry and ethnopharmacological aspects of genus calendula. | this review includes 84 references on the genus calendula (asteraceae) and comprises ethnopharmacology, morphology and microscopy, phytoconstituents, pharmacological reports, clinical studies and toxicology of the prominent species of calendula. triterpene alcohols, triterpene saponins, flavonoids, carotenoids and polysaccharides constitute major classes of phytoconstituents of the genus. a few species of this genus have medicinal value, among these calendula officinalis linn., has been traditio ... | 2013 | 24347926 |
| complete genome sequence of bacillus amyloliquefaciens strain co1-6, a plant growth-promoting rhizobacterium of calendula officinalis. | the genome sequence of bacillus amyloliquefaciens strain co1-6, a plant growth-promoting rhizobacterium (pgpr) with broad-spectrum antagonistic activity against plant-pathogenic fungi, bacteria, and nematodes, consists of a single 3.9-mb circular chromosome. the genome reveals genes putatively responsible for its promising biocontrol and pgp properties. | 2015 | 26272562 |
| repellency effects of essential oils of myrtle (myrtus communis), marigold (calendula officinalis) compared with deet against anopheles stephensi on human volunteers. | malaria and leishmaniasis are two most significant parasitic diseases which are endemic in iran. over the past decades, interest in botanical repellents has increased as a result of safety to human. the comparative efficacy of essential oils of two native plants, myrtle (myrtus communis) and marigold (calendula officinalis) collected from natural habitats at southern iran was compared with deet as synthetic repellent against anopheles stephensi on human subjects under laboratory condition. | 2011 | 22808414 |
| wound healing and anti-inflammatory effect in animal models of calendula officinalis l. growing in brazil. | calendula officinalis is an annual herb from mediterranean origin which is popularly used in wound healing and as an anti-inflammatory agent. in this study, the ethanolic extract, the dichloromethane, and hexanic fractions of the flowers from plants growing in brazil were produced. the angiogenic activity of the extract and fractions was evaluated through the chorioallantoic membrane and cutaneous wounds in rat models. the healing activity of the extract was evaluated by the same cutaneous wound ... | 2012 | 22315631 |
| a study on genetic variability of pathogenic aeromonas hydrophila strains and the varied responses of the strains towards phyto-extracts. | the present study evaluated genetic variation in aeromonas hydrophila strains using pcr-rapd and their varied susceptibility to phyto-extract. four strains of aeromonas hydrophila isolated from skin infections of common freshwater fish, cyprinus carpio were characterized by various biochemical methods, physiological tests and pcr- rapd. antimicrobial activity of the leaf extracts of three medicinal plants, ocimum sanctum, adathoda vasica and calendula officinalis were tested against the four str ... | 2013 | 24511738 |
| production of oleanolic acid glycosides by hairy root established cultures of calendula officinalis l. | in order to initiate hairy root culture initiation cotyledons and hypocotyls of calendula officinalis l. were infected with agrobacterium rhizogenes strain atcc 15834 or the same strain containing pcambia 1381z vector with β-glucuronidase reporter gene under control of promoter of nik (nematode induced kinase) gene. the efficiency of induction of hairy roots reached 33.8% for cotyledons and 66.6% for hypocotyls together for both transformation experiments. finally, eight control and nine modifie ... | 2013 | 24040627 |
| biocontrol and plant growth promotion characterization of bacillus species isolated from calendula officinalis rhizosphere. | the phenotypic and genotypic diversity of the plant growth promoting bacillus genus have been widely investigated in the rhizosphere of various agricultural crops. however, to our knowledge this is the first report on the bacillus species isolated from the rhizosphere of calendula officinalis. 15 % of the isolated bacteria were screened for their important antifungal activity against fusarium oxysporum, botrytis cinerea, aspergillus niger, cladosporium cucumerinium and alternaria alternata. the ... | 2013 | 24426149 |
| assessment of the microbial load of some medicinal plants commonly used in romania. | this study aims to assess the microbial load of some medicinal plants (matricaria chamomilla, achillea millefolium, ocimum basilicum, calendula officinalis, tilia cordata, hypericum perforatum) commonly used as medicinal teas. | 2015 | 25970977 |
| essential oils and herbal extracts as antimicrobial agents in cosmetic emulsion. | the cosmetic industry adapts to the needs of consumers seeking to limit the use of preservatives and develop of preservative-free or self-preserving cosmetics, where preservatives are replaced by raw materials of plant origin. the aim of study was a comparison of the antimicrobial activity of extracts (matricaria chamomilla, aloe vera, calendula officinalis) and essential oils (lavandulla officinallis, melaleuca alternifolia, cinnamomum zeylanicum) with methylparaben. extracts (2.5 %), essential ... | 2013 | 24426114 |
| in vitro studies to evaluate the wound healing properties of calendula officinalis extracts. | calendula officinalis (pot marigold) flower extracts have a long-lasting tradition in ethnopharmacology. currently, the european medicines agency (ema) has approved its lipophilic and aqueous alcoholic extracts as traditional medicinal products for the treatment of minor inflammation of the skin and as an aid in the healing of minor wounds. | 2017 | 27956358 |
| changes in heligmosomoides polygyrus glycoprotein pattern by saponins impact the balb/c mice immune response. | saponins of marigold (calendula officinalis), in particular derivatives of 3-o-monoglucuronide of oleanolic acid, are able to reduce infectivity of heligmosomoides polygyrus in mice. the purpose of this study was to understand the immune activation provoked by third-stage larvae exposed to marigold glucuronides. we also examined the pattern of glycosylation of larval antigens which appeared to be crucial for induction of cytokine production in balb/c mice; higher concentrations of il-6, ifn-γ, i ... | 2013 | 24036322 |
| [evaluation of the antiviral activity of medicinal plants against the hepatitis b virus (hbv) in plc/prf/5 cells]. | calendula officinalis l., psidium guajava l., eucaliptus spp. y phyllanthus orbicularis hbk against the hepatitis b virus were evaluated at subtoxic concentrations in the in vitro plc/prf/5 system or alexander cells, a cell line expressing constitutively the virus surface antigen (agshb). the cell viability parameter that was measured by the calculation of the mean cytotoxic concentration values (cc50): eucalyptus spp. showed a lower toxicity in the cells, followed by psidium guajava l., phyllan ... | 2013 | 23427427 |
| in vitro anti-leishmanial activity of methanolic extracts of calendula officinalis flowers, datura stramonium seeds, and salvia officinalis leaves. | the anti-leishmanial activity of methanolic extracts of calendula officinalis flowers, datura stramonium seeds, and salvia officinalis leaves against extracellular (promastigote) and intracellular (amastigote) forms of leishmania major were evaluated in this study. | 2014 | 24969522 |
| in vitro growth-inhibitory effect of brazilian plants extracts against paenibacillus larvae and toxicity in bees. | american foulbrood (afb) is a serious worldwide spreading disease in bees caused by paenibacillus larvae. plants extracts are known to decrease or inhibit the growth of these bacteria. the purpose of this study was to evaluate the antimicrobial activity of calendula. officinalis, cariniana domestica, and nasturtium officinale extracts against the p. larvae and to evaluate the toxicity of the extracts in bees. in vitro activity against p. larvae of the extracts was evaluated by micro dilution met ... | 2015 | 26062113 |
| biological activities of asteraceae (achillea millefolium and calendula officinalis) and lamiaceae (melissa officinalis and origanum majorana) plant extracts. | asteraceae (achillea millefolium and calendula officinalis) and lamiaceae (melissa officinalis and origanum majorana) extracts were obtained by applying two sequential extraction processes: supercritical fluid extraction with carbon dioxide, followed by ultrasonic assisted extraction using green solvents (ethanol and ethanol:water 50:50). the extracts were analyzed in terms of the total content of phenolic compounds and the content of flavonoids; the volatile oil composition of supercritical ext ... | 2017 | 28101823 |
| [investigation of metal element content of some european and far eastern herbs]. | metal elements and their excess intake have significant influence on general health. | 2015 | 26211750 |
| contact dermatitis as an adverse reaction to some topically used european herbal medicinal products - part 1: achillea millefolium-curcuma longa. | this review focuses on contact dermatitis as an adverse effect of a selection of topically used herbal medicinal products for which the european medicines agency has completed an evaluation up to the end of november 2013 and for which a community herbal monograph has been produced. part 1: achillea millefolium l.-curcuma longa l. | 2014 | 24621152 |
| antioxidative/acetylcholinesterase inhibitory activity of some asteraceae plants. | the extracts obtained by 80% etoh from some asteraceae plants (calendula officinalis, inula helenium, arctium lappa, artemisia absinthium and achillea millefolium) were studied. rosmarinic acid, one of the main compounds identified in all extracts, was determined quantitatively by using hplc. in addition, spectrophotometric methods were evaluated as an alternative for rosmarinic acid content determination. total phenolic content was also established for all extracts. a. millefolium extract was f ... | 2013 | 23738456 |
| adverse effects of herbal medicines: an overview of systematic reviews. | this overview of systematic reviews (srs) aims to evaluate critically the evidence regarding the adverse effects of herbal medicines (hms). five electronic databases were searched to identify all relevant srs, with 50 srs of 50 different hms meeting our inclusion criteria. most had only minor weaknesses in methods. serious adverse effects were noted only for four hms: herbae pulvis standardisatus, larrea tridentate, piper methysticum and cassia senna. the most severe adverse effects were liver o ... | 2013 | 23472485 |