| saccharopolyspora gloriosae sp. nov., an endophytic actinomycete isolated from the stem of gloriosa superba l. | a gram-stain-positive, aerobic actinomycete, strain yim 60513(t), was isolated from the stem of gloriosa superba l. collected from tropical rainforest at xishuangbanna, yunnan province, south-west china. 16s rrna gene sequence analysis indicated that strain yim 60513(t) belonged to the genus saccharopolyspora and was closely related to saccharopolyspora gregorii ncib 12823(t) (99.1 % similarity) and saccharopolyspora cebuensis spe 10-1(t) (97.3 % similarity). data for the predominant quinone [mk ... | 2010 | 19666795 |
| adulticidal and larvicidal efficacy of some medicinal plant extracts against tick, fluke and mosquitoes. | the adulticidal and larvicidal effect of indigenous plant extracts were investigated against the adult cattle tick haemaphysalis bispinosa neumann, 1897 (acarina: ixodidae), sheep fluke paramphistomum cervi zeder, 1790 (digenea: paramphistomatidae), fourth instar larvae of malaria vector, anopheles subpictus grassi and japanese encephalitis vector, culex tritaeniorhynchus giles (diptera: culicidae). the aim of this study was to evaluate the toxic effect of leaf hexane, chloroform, ethyl acetate, ... | 2009 | 19819626 |
| evaluation of antileishmanial activity of south indian medicinal plants against leishmania donovani. | infections due to protozoa of the genus leishmania are a major worldwide health problem, with high endemicity in developing countries. the aim of this study was to evaluate the in vitro antileishmanial activity of the acetone and methanol leaf extracts of anisomeles malabarica, flower of gloriosa superba, leaf of ocimum basilicum, leaf and seed of ricinus communis against promastigotes form of leishmania donovani. antiparasitic evaluations of different plant crude extracts were performed on 96 w ... | 2012 | 22771864 |
| evaluation of the colchicine-like activity of gloriosa superba-extracted fractions for mosquito (diptera: culicidae) cytogenetic study. | four fractions of gloriosa superba l., i.e., hexane fraction, dichloromethane fraction 1, dichloromethane fraction 2, and methanol fraction, were investigated for colchicine-like activity using a mosquito cytogenetic assay. the results revealed that the latter three fractions yielded promisingly high colchicine-like activity, whereas the hexane fraction yielded very low activity compared with 1% colchicine in a 0.85% sodium chloride solution. the metaphase rates and average number of metaphase c ... | 2004 | 15311459 |
| the application of ethanol-extracted gloriosa superba for metaphase chromosome preparation in mosquitos. | the application of ethanol-extracted gloriosa superba for metaphase chromosome preparation in adult and 4th larva aedes aegypti revealed that 0.5-8% ethanol-extracted gl. superba solution could be used instead of 1% colchicine in hanks' balanced salt solution. for adult mosquitos, the metaphase rates and average number of metaphase chromosomes per positive mosquito after intrathoracic inoculation with 1-2% ethanol-extracted gl. superba solution were 100% and 11.8 (2-16) -12.6 (3-28) in females, ... | 2001 | 11485100 |
| screening of ten plant species for metaphase chromosome preparation in adult mosquitoes (diptera: culicidae) using an inoculation technique. | the screening of 10 plant species (aloe barbadensis mill., asparagus officinalis l., as. plumosus bak., as. racemosus willd., as. sprengeri regel, codyline fruticosa goppert, dracaena loureiri gagnep., gloriosa superba l., hemerocallis flava l., and sansevieria cylindrica bojer) for colchicine-like substance(s) using a mosquito cytogenetic assay revealed that a 1% solution of dried gl. superba rhizome extracted in 0.85% sodium chloride solution could be used instead of a 1% colchicine in hanks' ... | 1999 | 10593098 |
| colchicine poisoning following ingestion of gloriosa superba tubers. | | 2015 | 4693992 |
| antihaemolytic and snake venom neutralizing effect of some indian medicinal plants. | to validate traditional claims of usefulness of the indian plants in management of poisonous snakebite and evaluate the antivenom properties displayed by the alcoholic extracts of andrographis paniculata (a. paniculata), crateva magna (c. magna), gloriosa superba (g. superba) and hydrocotyle javanica (h. javanica). | 2011 | 21967700 |
| [case of colchicine intoxication caused by tubers of gloriosa superba]. | gloriosa superba is one of the poisonous plants growing in japan. it contains potent alkaloid such as colchicine which binds to tubulin and prevents it from forming microtubules that are part of the cytoskeleton in human cells. ingestion of gloriosa superba tubers causes severe and potentially fatal toxic effects. we report here a case of colchicine intoxication caused by tubers of gloriosa superba. a 58-year-old male ingested about 25 g of gloriosa superba tubers by mistake. he believed that it ... | 2010 | 20865911 |
| in vitro antimalarial activity of medicinal plant extracts against plasmodium falciparum. | malaria is a major global public health problem, and the alarming spread of drug resistance and limited number of effective drugs now available underline how important it is to discover new antimalarial compounds. in the present study, ten plants were extracted with ethyl acetate and methanol and tested for their antimalarial activity against chloroquine (cq)-sensitive (3d7) and cq-resistant (dd2 and indo) strains of plasmodium falciparum in culture using the fluorescence-based sybr green assay. ... | 2011 | 20809417 |
| isolation and anti-inflammatory activity of colchicinoids from gloriosa superba seeds. | gloriosa superba l. (liliaceae) seeds, known as "kalihari" (hindi), were phytochemically investigated for colchicine (well known for gout treatment) and other related alkaloid content. colchicine, 2- demethylcolchicine, 3-demethylcolchicine, and n-formyl-n-deacetylcolchicine were alkaloids isolated from the seeds. the isolated samples have been standardized for their purity with respect to the reference standard using hplc. the structures were confirmed by nmr spectroscopy and were analyzed by s ... | 2010 | 20645842 |
| evaluation of botanical extracts against haemaphysalis bispinosa neumann and hippobosca maculata leach. | in the current study, in vitro evaluation of crude hexane, chloroform, ethyl acetate, acetone, and methanol extracts of anisomeles malabarica (l.) r. br., gloriosa superba l., psidium guajava l., ricinus communis l., and solanum trilobatum l. exhibited acaricidal and insecticidal activities against the adult of haemaphysalis bispinosa neumann (acarina: ixodidae) and hematophagous fly hippobosca maculata leach (diptera: hippoboscidae). all plant extracts showed moderate toxic effect on parasites ... | 2010 | 20467752 |
| laboratory determination of efficacy of indigenous plant extracts for parasites control. | the present study was based on assessments of the antiparasitic activities to determine the efficacies of acetone, chloroform, ethyl acetate, hexane, and methanol dried leaf, flower, and seed extracts of achyranthes aspera l., anisomeles malabarica (l.) r. br., gloriosa superba l., psidium guajava l., ricinus communis l., and solanum trilobatum l. tested against the larvae of cattle tick rhipicephalus (boophilus) microplus (canestrini 1887) (acari: ixodidae), sheep internal parasite paramphistom ... | 2009 | 19308453 |
| colchicine semisynthetics: chemotherapeutics for cancer? | nitrogen-containing bioactive alkaloids of plant origin play a significant role in human health and medicine. several semisynthetic antimitotic alkaloids are successful in anticancer drug development. gloriosa superba biosynthesizes substantial quantities of colchicine, a bioactive molecule for gout treatment. colchicine also has antimitotic activity, preventing growth of cancer cells by interacting with microtubules, which could lead to the design of better cancer therapeutics. further, several ... | 2013 | 23210778 |
| antimicrobial activities of gloriosa superba linn (colchicaceae) extracts. | the methanol extract of the rhizomes of gloriosa superba linn (colchicaceae) and its subsequent fractions in different solvent systems were screened for antibacterial and antifungal activities. excellent antifungal sensitivity was expressed by the n-butanol fraction against candida albicans and candida glaberata (up to 90%) and against trichophyton longifusus (78%) followed by the chloroform fraction against microsporum canis (80%). in the antibacterial bioassay, the crude extract and subsequent ... | 2008 | 18615278 |
| ethnobotanical survey of folk plants for the treatment of snakebites in southern part of tamilnadu, india. | ethnobotanical surveys were conducted in four different indigenous groups in southern parts of tamilnadu, india, using a questionnaire. the herbal practitioners in the study area were interviewed, and information on medicinal plants was collected from the traditional healers called "vaidyars". this survey covers 72 medicinal plants belonging to 53 families that are used for the treatment of snakebite in a traditional way. traditional approach was evaluated scientifically with some selected plant ... | 2008 | 18055146 |
| thiocolchicoside a semi-synthetic derivative of the glory lily: a new weapon to fight metastatic bone resorption? | metastatic bone disease is a serious clinical complication for the treatment of patients with advanced cancer, but few therapeutic options are currently available. bisphosphonates are an established standard care for these patients, but new treatments are now emerging, including the use of monoclonal antibodies targeting the rank ligand. in this issue of the bjp, reuter et al. provide evidence that thiocolchicoside, a semi-synthetic derivative of the naturally occurring colchicoside, extracted f ... | 2012 | 22122264 |
| thiocolchicoside suppresses osteoclastogenesis induced by rankl and cancer cells through inhibition of inflammatory pathways: a new use for an old drug. | most patients with cancer die not because of the tumour in the primary site, but because it has spread to other sites. common tumours, such as breast, multiple myeloma, and prostate tumours, frequently metastasize to the bone. to search for an inhibitor of cancer-induced bone loss, we investigated the effect of thiocolchicoside, a semi-synthetic colchicoside derived from the plant gloriosa superba and clinically used as a muscle relaxant, on osteoclastogenesis induced by receptor activator of nf ... | 2012 | 21955206 |
| critical review on medicinally potent plant species: gloriosa superba. | gloriosa superba l. is a perennial climber and is used as an ayurvedic medicinal herb to cure diseases in various parts of africa and southeast asia. the plant was under threatened category due to its imprudent harvesting from wild as it is extensively used by medicinal industries for its colchicine content. it also faces a low seed set problem, but due to its industrial demand it is now under cultivation. the plant is used to cure arthritis, gout, rheumatism, inflammation, ulcers, bleeding pile ... | 2011 | 21059382 |
| purification of 3 monomeric monocot mannose-binding lectins and their evaluation for antipoxviral activity: potential applications in multiple viral diseases caused by enveloped viruses. | three monomeric monocot lectins from zephyranthes carinata, zephyranthes candida, and gloriosa superba with carbohydrate specificity towards mannose derivatives and (or) oligomannose have been isolated and purified from their storage tissues. the lectins were purified by anion-exchange chromatography on deae-sephacyl and by gel filtration chromatography on biogel p-200 followed by high-performance liquid chromatography. the purified lectins, z. carinata, z. candida, and g. superba had molecular ... | 2007 | 17464348 |
| aluminium chloride enhances colchicine production in root cultures of gloriosa superba. | root cultures of gloriosa superba were treated with 5 mm: methyl jasmonate and 125 microm: alcl3 which enhanced the intracellular colchicine content of the roots by 50-fold and 63-fold, respectively. ten millimolar of cacl2 and 1 mm: cdcl2 enhanced biomass significantly (7- to 8.6-fold, respectively) while maximum release of colchicine into the medium was obtained with 10 mm: cdcl2. casein hydrolysate, yeast extract and silver nitrate had no significant effect on growth and colchicine accumulati ... | 2006 | 16614932 |
| [neurological syndromes linked with the intake of plants and fungi containing a toxic component (i). neurotoxic syndromes caused by the ingestion of plants, seeds and fruits]. | a wide range of plants, seeds and fruits used for nutritional and medicinal purposes can give rise to neurotoxic symptoms. | 2003 | 12717675 |
| potent antiproliferative effect on liver cancer of medicinal plants selected from the thai/lanna medicinal plant recipe database "manosroi iii". | thai/lanna medicinal plant recipes have been used for the treatment of several diseases including liver cancer. in this study, methanolic extracts (mes) of 23 plants were tested for antiproliferative activity on human hepatoma cell line (hep g2) by the sulforhodamine b (srb) assay. nine mes with potent antiproliferative activity (ic50 < 100 µg/ml) were obtained and further semipurified by liquid/liquid partition extraction. the semipurified fractions were tested for the antiproliferative and ant ... | 2015 | 26136809 |
| gloriosa superba poisoning mimicking an acute infection- a case report. | gloriosa superba (gsb) is a highly poisonous plant and its toxicity is due to anti-mitotic effects of constituents such as colchicine and gloriosine on rapidly proliferating cells. poisoning is known to cause very rapid and severe clinical manifestations due gastro intestinal, neurological, cardiac and bone marrow toxicity. | 2015 | 26415509 |
| colchicine-induced rhabdomyolysis: an autopsy case. | colchicine is derived from colchicum autumnale and gloriosa superba and is used to treat acute gout and familial mediterranean fever (fmf). musculoskeletal adverse effects range from myopathy to rhabdomyolysis. an 18-year-old woman, with a 2-year history of fmf treated with colchicine, took 9 colchicine pills (4.5 mg) to relieve severe abdominal pain. on the sixth day of hospitalization, the patient's condition worsened, and she died. as this was a case of fatal poisoning, a forensic autopsy was ... | 2016 | 27049658 |
| a new glycoside, 3-o-demethylcolchicine-3-o-alpha-d-glucopyranoside, from gloriosa superba seeds. | a new colchicine glycoside, 3-o-demethylcolchicine-3-o-alpha-d-glucopyranoside, has been isolated from gloriosa superba seeds. the assigned structure has been corroborated by spectroscopic data and enzymatic hydrolysis. | 2001 | 11833615 |
| somatic embryogenesis and plant regeneration in gloriosa l. | friable callus was initiated from shoot apices of gloriosa superba l. on basal ms medium supplemented with 2, 4-d (4mg l(-1)) + kn(5 mg l(-1)) + ch(10 mg l(-1)) + cw(20%). subculture of callus on the same medium after 4-5 weeks showed induction of large number of somatic embryos, which was confirmed with histological studies. development of embryoids in plantlet took place when the embryogenic callus was transferred to basal ms medium supplemented with bap (5 mg l(-1)), ch(50 mg l(-1)) +cw(20%). ... | 2001 | 11831383 |
| gloriosa superba poisoning. | suicidal attempts by consuming poisonous extracts of a creeper plant gloriosa superba are frequent in this region. an instance of such poisoning is reported here, wherein a family engaged in business dealing with this plant consumed the crude liquid extract of its root. the symptoms were mainly gastrointestinal. the children had more severe symptoms which included sweating, hypotension, jaundice, bradycardia and convulsions. the features were reversible with symptomatic treatment alone. | 1992 | 1308494 |
| efficacy screening of gloriosa superba extracts in a murine pancreatic cancer model using (18)f-fdg pet/ct for monitoring treatment response. | in vivo efficacy of two herbal extracts of gloriosa superba l. (colchicaceae) was investigated in a murine pancreatic tumor model by tumor volume measurements and positron emission tomography (pet) imaging using 2-deoxy-2-[(18)f]fluoro-d-glucose ((18)f-fdg). | 2016 | 27093343 |
| comparison of seeds of colchicum speciosum and gloriosa superba in respect to colchicine and colchicoside contents by rp-lc. | in this study, colchicine (cln) and colchicoside (cls) contents of the methanolic extracts of the seeds of colchicum speciosum steven that were collected from uzungöl, trabzon and also the seeds belonging to two different samples of gloriosa superba linn. imported from india were compared by using rp-lc (reversed phase high pressure liquid chromatography). this proposed method is advantageous in terms of sample preparation and selective separation of the compounds. also the method was successful ... | 2016 | 27169190 |
| case report: a rare case of attempted homicide with gloriosa superba seeds. | gloriosa superba, well known as the glory lily or superb lily, is a tropical climbing plant that features an exotic red flower. the plant is poisonous because of high concentrations of colchicine in all parts of the plant. it is commercially grown for use in ayurveda medicine and as a cash crop for extracting colchicine in india and africa. it is a wild plant in sri lanka and commercial cultivation is rare. accidental and suicidal poisonings with gloriosa tubers are well known and reported. ther ... | 2016 | 27324655 |
| [gloriosa superba l. and the production of colchicinic substances]. | | 1985 | 3837621 |
| substances from plants of the subfamily wurmbaeoideae and their derivatives. part lxxix. alkaloids of the plant gloriosa superba l. | | 1975 | 1197428 |
| acute ascending polyneuropathy and dermatitis following poisoning by tubers of gloriosa superba. | | 1971 | 5154236 |
| massive generalized alopecia after poisoning by gloriosa superba. | | 1966 | 5909848 |
| [isolation of substances from various portions of east indian gloriosa superba l. 48. substances of meadow saffron & its derivatives]. | | 2013 | 13459362 |
| [studies on constituent substances in gloriosa superba]. | | 1953 | 13133725 |
| doubling of chromosomes induced by gloriosine isolated from gloriosa superba, linn. | | 1953 | 13054717 |
| [isolation of substances from the bulbs of gloriosa superba l., gloriosa rothchildiana o'brien and gloriosa simplex]. | | 1952 | 13003514 |
| death through eating tubers of gloriosa superba. | | 1946 | 20245532 |
| anagen effluvium secondary to gloriosa superba ingestion. | anagen effluvium, the shedding of anagen hair, leads to diffuse non-scarring alopecia. we report two cases of anagen effluvium in the same family secondary to the ingestion of tubers of gloriosa superba, which contains the antimitotic alkaloid colchicine. both patients developed anagen effluvium and gastroenteritis 1-2 weeks after consuming the tubers. in addition, one of them had bicytopenia, pleural effusion, hematuria and altered liver function tests. both were managed conservatively and coun ... | 2016 | 27451928 |
| coadministration of a gloriosa superba extract improves the in vivo antitumoural activity of gemcitabine in a murine pancreatic tumour model. | gloriosa superba l. (glory lily, colchicaceae) contains colchicine, and related alkaloids such as 3-o-demethylcolchicine and its glycoside colchicoside. previously the in vivo efficacy of a crude extract and a colchicine-poor / colchicoside-rich extract of g. superba seeds was shown in a murine model of pancreatic adenocarcinoma. | 2016 | 27765363 |
| green synthesis of silver, gold and silver/gold bimetallic nanoparticles using the gloriosa superba leaf extract and their antibacterial and antibiofilm activities. | the green fabrication of metal nanoparticles using botanical extracts is gaining increasing research attention in nanotechnology, since it does not require high energy inputs or the production of highly toxic chemical byproducts. here, silver (ag), gold (au) and their bimetallic (ag/au) nanoparticles (nps) were green synthesized using the gloriosa superba aqueous leaf extract. metal nps were studied by spectroscopic (uv-visible spectroscopy, fluorescence spectroscopy, ft-ir spectroscopy, xrd and ... | 2016 | 27765621 |
| toxic encephalopathy due to colchicine--gloriosa superba poisoning. | gloriosa superba, a flowering plant widespread in south and southeast asia, is implicated in many cases of self-poisoning. colchicine is concentrated in the seeds and tubers and this mediates its toxicity. we describe a 28-year-old woman who developed delayed encephalopathy after eating g superba tubers. mr scan of brain showed bilateral symmetrical t2 basal ganglia hyperintensities in the caudate and lentiform nuclei. the delay in onset of encephalopathy is attributable to a direct-effect colch ... | 2014 | 24591648 |
| improved growth and colchicine concentration in gloriosa superba on mycorrhizal inoculation supplemented with phosphorus-fertilizer. | gloriosa superba produces an array of alkaloids including colchicine, a compound of interest in the treatment of various diseases. the tuber of gloriosa superba is a rich source of colchicine which has shown anti-gout, anti-inflammatory, and anti-tumor activity. however, this promising compound remains expensive and gloriosa superba is such a good source in global scale. increase in yield of naturally occurring colchicine is an important area of investigation. | 2014 | 25435630 |
| in vitro anti-proliferative activity on colon cancer cell line (ht-29) of thai medicinal plants selected from thai/lanna medicinal plant recipe database "manosroi iii". | thai/lanna region has its own folklore wisdoms including the traditional medicinal plant recipes. thai/lanna medicinal plant recipe database "manosroi iii" has been developed by prof. dr. jiradej manosroi. it consists of over 200,000 recipes for all diseases including cancer. to investigate the anti-proliferative and apoptotic activities on human colon cancer cell line (ht-29) as well as the cancer cell selectivity of the methanolic extracts (mes) and fractions of the 23 selected plants from the ... | 2015 | 25481081 |
| retraction notice to green synthesis of silver nanoparticles from gloriosa superba.l leaf extract and their catalytic activity [saa 115c 388-392]. | | 2017 | 27939415 |
| isolation and structure elucidation of glucosylated colchicinoids from the seeds of gloriosa superba by lc-dad-spe-nmr. | four new colchicinoids were isolated from the seeds of gloriosa superba together with the known compounds colchicoside (4) and 3-de-o-methylcolchicine-3-o-β-d-glucopyranosyl-(1→4)-3-o-β-d-glucopyranoside (6), by means of conventional column chromatography and lc-dad-spe-nmr. the new compounds were identified as n-deacetyl-n-formyl-3-de-o-methylcolchicine-3-o-β-d-glucopyranoside (1), 3-de-o-methylcolchicine-3-o-β-d-glucopyranosyl-(1→6)-3-o-β-d-glucopyranoside (2), n-deacetyl-n-formyl-3-de-o-methy ... | 2017 | 28211687 |
| upstream biomanufacturing of pharmaceutical colchicine. | the plant-based colchicine potentially affects major diseases such as cardiovascular events, cancers and gout. gloriosa superba seeds are a conventional pharmaceutical source of colchicine. the demand for pharmaceutical-grade colchicine has increased due to the shortage of feasible upstream manufacturing, encompassing all stages in the processes of biosynthesis and biomanufacturing before the raw material is ready for purification. consequently, developing sustainable upstream industrial colchic ... | 2017 | 28399663 |
| effect of gloriosa superba and catharanthus roseus extracts on ifn-γ-induced keratin 17 expression in hacat human keratinocytes. | gloriosa superba and catharanthus roseus are useful in traditional medicine for treatment of various skin diseases and cancer. however, their molecular effect on psoriasis has not been investigated. in this study, the effect of ethanol extracts derived from g. superba leaves and c. roseus stems on the expression of psoriatic marker, keratin 17 (k17), was investigated in human keratinocytes using biochemical and molecular experimental approaches. both extracts could reduce the expression of k17 i ... | 2014 | 25435888 |
| gloriosa superba ingestion: hair loss and acute renal failure. | gloriosa superba is a plant that grows wild in several parts of south india. tubers of this plant contain several alkaloids. acute intoxication following the ingestion of g. superba results in gastrointestinal and haematological abnormalities, hepatic and renal insufficiency, cardiotoxicity and hair loss. we present a case with typical features of g superba toxicity. | 2017 | 26060369 |
| the complete chloroplast genome of colchicine plants (colchicum autumnale l. and gloriosa superba l.) and its application for identifying the genus. | the complete chloroplast genome of two colchicine medicinal plants is reported for the first time. deletion of ycf 15 gene occurred only in colchicum but not in gloriosa and suggests this as a potential marker for delineating the two species. colchicum autumnale l. and gloriosa superba l. are well-known sources of colchicine, a type of alkaloid and an ancient anti-inflammatory drug used to prevent gout. accordingly, this alkaloid has been used as a chemical marker for identifying the expanded co ... | 2015 | 25904477 |
| synthesis of cerium oxide nanoparticles using gloriosa superba l. leaf extract and their structural, optical and antibacterial properties. | ceo2 nanoparticles (nps) were green synthesized using gloriosa superba l. leaf extract. the synthesized nanoparticles retained the cubic structure, which was confirmed by x-ray diffraction studies. the oxidation states of the elements (c (1s), o (1s) and ce (3d)) were confirmed by xps studies. tem images showed that the nps possessed spherical shape and particle size of 5nm. the ce-o stretching bands were observed at 451cm(-1) and 457cm(-1) from the ft-ir and raman spectra respectively. the band ... | 2015 | 25686966 |
| potent anti-proliferative effects against oral and cervical cancers of thai medicinal plants selected from the thai/lanna medicinal plant recipe database "manosroi iii". | thai/lanna medicinal plant recipes have been used for the treatment of several diseases including oral and cervical cancers. | 2015 | 25612774 |
| green synthesis of silver nanoparticles from gloriosa superba l. leaf extract and their catalytic activity. | the present work focuses the use of aqueous extract of gloriosa superba linn. (glory lily) for producing silver nanoparticles (agnps) from silver nitrate aqueous solution. phytochemical analysis of the extract revealed the presence of alkaloid, amino acids, carbohydrates and proteins in the extract and they serve as effective reducing and capping agents for converting silver nitrate to silver nanoparticles. the nanoparticles were characterised by uv (ultra violet), ft-ir (fourier transform infra ... | 2013 | 23860402 |
| evaluation of genetic fidelity among micropropagated plants of gloriosa superba l. using dna-based markers--a potential medicinal plant. | malabar glory lily (gloriosa superba l.) is a medicinally potent plant species used for the production of alkaloid colchicine. with ever increasing demand, there is a pressing need to conserve it through biotechnological approaches. a large number of complete plantlets were obtained by direct regeneration from the non-dormant tuber explants on murashige and skoog (ms) medium supplemented with 2.0 mg/l 6-benzylaminopurine (bap)+0.5 mg/l α-naphthalene acetic acid (naa). large number of plants can ... | 2013 | 23811099 |
| colchicine poisoning: a case report and review of literature. | colchicine, a natural pseudo-alkaloid found in plants such as the colchicum autumnale and gloriosa superba has tremendous medicinal properties, but if misused by an unqualified person can result in fatal consequences. we report a case of colchicine poisoning in an adult man as a result of consumption of the herb g. superba by a 50-year-old man and review the literature. | 2012 | 22941521 |
| hard facts about loose stools - massive alopecia in gloriosa superba poisoning. | | 2011 | 22223980 |
| thiocolchicoside exhibits anticancer effects through downregulation of nf-κb pathway and its regulated gene products linked to inflammation and cancer. | the discovery of new uses for older, clinically approved drugs is one way to expedite drug development for cancer. thiocolchicoside, a semisynthetic colchicoside from the plant gloriosa superba, is a muscle relaxant and used to treat rheumatologic and orthopedic disorders because of its analgesic and anti-inflammatory mechanisms. given that activation of the transcription factor nf-κb plays a major role in inflammation and tumorigenesis, we postulated that thiocolchicoside would inhibit nf-κb an ... | 2010 | 20978115 |
| a comparative study on growth pattern of langali (gloriosa superba linn.) under wild and cultivated conditions. | langali (gloriosa superba linn.), obtained from wild habitat and by experimental cultivation under three groups, viz., control, cultivated as per the modern agricultural guidelines and as per the norms of vriksha-ayurveda was compared and analyzed. methods of vriksha-ayurveda give good result in the case of langali in terms of yield. failure of control groups both in seed and tuber batches denotes that this plant needs some treatment for vegetative propagation under artificial conditions. ayurve ... | 2010 | 22131723 |
| [fatal colchicine poisoning--case report and review of literature]. | colchicine is a natural pseudo-alkaloid found in plants such as the autumn crocus (colchicum autumnale) and glory lily (gloriosa superba), which is used to treat gout and some other rheumatological disease. colchicine binds to tubuline and prevents its polymerization into microtubules. it is thus able to impair those cellular functions that involve microtubules, eg. it arrests mitosis in metaphase. tissues with high mitotic activity are preferentially affected. we report suicidal colchicine pois ... | 2010 | 21387793 |
| optimization of solvents for effective isolation of colchicines from gloriosa superba l. seeds. | to meet the strong demand of colchicine an attempt is made to optimize the solvent system for isolation of colchicine. gloriosa superba dried seed powder was extracted by using different solvents. maximum yield of colchicine was obtained when extracted with water and alcohol in the ratio of 50 : 50. | 2007 | 17487621 |
| embryoidogenesis and plant regeneration from leaf tissue of gloriosa superba. | the induction, maturation and germination of embryoids from leaf tissue of gloriosa superba l. were developed by exploiting solid and liquid culture. nodular calli were obtained from sh medium supplemented with 2,4-d and 2ip. in solid culture, the nodular calli when transferred to 2,4-d along with glycerol gave the best response (68.4 %) in embryoid induction after 20 days. after two subcultures at 7-day intervals in a medium with thiamine instead of glycerol, the embryoids matured. when mature ... | 2003 | 12802738 |
| poisoning with plants and mushrooms in sri lanka: a retrospective hospital based study. | a retrospective hospital-based study in sri lanka showed that out of 4556 cases of poisoning, 2.5% were caused by plants and mushrooms. gloriosa superba (44%), and ricinus communis (24%) were the commonest plants responsible for poisoning; 39% of the victims were less than 15 y old. gastric lavage and iv fluids were the most common therapeutic measures used. there were 8 deaths, all due to g superba. there is a need for public education to prevent poisoning, which is a major health concern. | 1990 | 2264272 |
| colchicine cardiotoxicity following ingestion of gloriosa superba tubers. | the clinical features of colchicine toxicity in a patient following ingestion of gloriosa superba tubers are described. gastroenteritis, acute renal failure, cardiotoxicity and haematological abnormalities were the main toxic manifestations. there was no hypotension and no neurological manifestations. electrocardiographic changes were noteworthy and have not been reported previously. | 1989 | 2694138 |
| a rare case of poisoning by gloriosa superba. | | 1988 | 3204092 |
| enzyme inhibition activities of the extracts from rhizomes of gloriosa superba linn (colchicaceae). | an alcoholic extract obtained from the rhizomes of gloriosa superba linn (colchicaceae) was screened for enzyme inhibition activities. the crude extract and its subsequent fractions including chloroform, ethyl acetate, n-butanol and aqueous were screened against lipoxygenase, actylcholinesterase, butyrylcholinesterase and urease. an outstanding inhibition on lipoxygenase was observed. the highest enzyme inhibition potency was expressed by the chloroform fraction (90%) among the tested fractions ... | 2007 | 18237025 |