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studies on vaccination against papillomaviruses: the immunity after infection and vaccination with bovine papillomaviruses of different types.calves, free of antibodies to bovine papillomaviruses (bpv), were reared in isolation. one was infected with bpv-2, developed tumours and was resistant to homologous reinfection. groups of calves were infected with bpv-2, bpv-5 or bpv-6; they all developed and subsequently rejected type-specific tumours. they were then infected with bpv-4; they were not immune and oral papillomas were induced. groups of animals were vaccinated by intramuscular preparations of purified bpv-4 and bpv-6 and were ch ...19902161579
papillomas of the teats and udder of cattle and their causal viruses.an abattoir survey was carried out on 1657 cattle to determine the incidence and parameters of teat and udder papillomas and their causal viruses. recent research has characterised six different bovine papillomaviruses of which three have been found to be particularly associated with teat tumours. of the population studied 37.3 per cent had teat warts and 86.2 per cent of these had multiple infections; 28.4 per cent had papillomas attributed to bovine papillomavirus 1, 88.5 per cent to bovine pa ...19846098066
bovine cutaneous papillomas associated with bovine papillomavirus type 5.squamous papillomas obtained from bovine facial skin yielded viral dna indistinguishable from that of bovine papillomavirus type 5. it was separated from recognised bovine papillomaviruses by its restriction endonuclease pattern and hybridization tests with dna.19947998842
bovine papillomavirus type 5: partial sequence and comparison with other bovine papillomaviruses.two restriction fragments of bovine papillomavirus type 5 (bpv5), of a genomic size of 1.6 and 1.2 kb were subcloned and sequenced. one of them seemed to correspond to the 3' end of the e1 open reading frame (orf) and the other to the region of the e7, e8 and 5' end of the e1 orf. alignments of these fragments with other bpvs showed that bpv5 is only distantly related to the other 5 bpvs.19979311560
presence of papillomavirus-like dna sequences in cutaneous fibropapillomas of the goat udder.papillomatous lesions were isolated from the mammary skin of goats and examined for evidence of papillomavirus (pv) infection by various criteria, including gross morphology, histology and dna hybridization. although some lesions showed gross papillomatous morphological and histological features similar to those caused by papillomavirus in other species, no viral particles were detected. reverse slot hybridization revealed cross-hybridization between dna extracted from goat mammary papillomas an ...19989646460
cloning and characterization of a novel caprine genomic repetitive element that hybridizes with papillomavirus dna.a goat genomic library was screened by southern blot hybridization at reduced stringency with a bovine papillomavirus type 5 (bpv 5) dna probe in order to identify potential cellular and viral sequences related to the papillomavirus genome. a recombinant clone with an 8.5 kb genomic insert was found to contain a 1.3 kb psti subfragment (designated as p1-1) that hybridized with the dna of bpv 5, two murine papillomaviruses and human papillomavirus types 5 and 8, but not with dna from another eigh ...200010768774
lack of the canonical prb-binding domain in the e7 orf of artiodactyl papillomaviruses is associated with the development of fibropapillomas.the l-x-c-x-e prb-binding motif of papillomavirus (pv) e7 proteins has been implicated in the immortalization and transformation of the host cell. however, sequencing of the complete genomes of bovine papillomavirus type 3 (bpv-3), bovine papillomavirus type 5 (bpv-5), equine papillomavirus (eqpv) and reindeer (rangifer tarandus) papillomavirus (rpv) supports the notion that the prb-binding motif is not ubiquitous among e7 proteins in the pv proteome. key among the animal groups that lack the pr ...200415105541
genome characterization of a bovine papillomavirus type 5 from cattle in the amazon region, brazil.papillomaviruses are small and complex viruses with circular dna genome that belongs to the papillomavirus family, which comprises at least 39 genera. the bovine papillomavirus (bpv) causes an infectious disease that is characterized by chronic and proliferative benign tumors that affect cattle worldwide. in the present work, the full genome sequence of bpv type 5, an epsilonpapillomavirus, is reported. the genome was recovered from papillomatous lesions excised from cattle raised in the amazon ...201727817150
genomic characterization of a novel epsilonpapillomavirus associated with pigmented papillomas in a red deer (cervus elaphus).two of a group of 15 farmed european red (cervus elaphus elaphus) x wapiti (c. e. canadensis) deer stags developed multiple persistent pigmented squamous papillomas (warts) on their chins. dna was extracted from a papilloma and a short section of dna from a novel papillomavirus (pv) was amplified. this short sequence was used to design 'outward facing' primers to amplify the remainder of the circular pv dna. the pcr product was sequenced using next-generation sequencing and the full genome of th ...201627154332
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