| modification of mitomycin c-induced clastogenicity by terminalia catappa l. in vitro and in vivo. | the water extract of the leaves of terminalia catappa l. was tested for inhibition of mitomycin c-induced micronuclei in cho-k1 cells. the simultaneous and pre-treatment of cho-k1 cells with t. catappa extract (75 and 150 micrograms/ml) significantly (p < 0.05) suppressed mitomycin c-induced micronuclei. furthermore, gastric intubation of t. catappa extract (4.8 and 24 mg/animal per day) to male icr mice for 8 days significantly (p < 0.01) reduced mitomycin c-induced micronuclei in peripheral bl ... | 1996 | 8689625 |
| antioxidant and hepatoprotective activity of punicalagin and punicalin on carbon tetrachloride-induced liver damage in rats. | punicalagin and punicalin, isolated from the leaves of terminalia catappa l., are used to treat dermatitis and hepatitis. both compounds have strong antioxidative activity. the antihepatotoxic activity of punicalagin and punicalin on carbon tetrachloride (ccl4)-induced toxicity in the rat liver was evaluated. levels of serum glutamate-oxalate-transaminase and glutamate-pyruvate-trans-aminase were increased by administration of ccl4 and reduced by drug treatment. histological changes around the l ... | 1998 | 9720629 |
| first isolation of cryptococcus neoformans var. gattii, serotype c, from the environment in colombia. | the natural habitat of cryptococcus neoformans var. gattii, serotype b in the environment was established by australian investigators who demonstrated its association with species of eucalyptus. the aim of the present study was to search for the habitat of this variety in a city of colombia, where clinical cases due to this variety occur with great frequency. for a period of 5 months detritus, vegetable material and air samples in and around 68 almond trees (terminalia catappa) located in the ci ... | 1998 | 10075505 |
| effects of punicalagin and punicalin on carrageenan-induced inflammation in rats. | punicalagin and punicalin were isolated from the leaves of terminalia catappa l. in this study, we evaluated the anti-inflammatory activity of punicalagin and punicalin carrageenan-induced hind paw edema in rats. after evaluation of the anti-inflammatory effects, the edema rates were increased by carrageenan administration and reduced by drug treatment. after 4 hr of carrageenan administration, the best effect group was the punicalagin (10 mg/kg) treated group (inhibition rate was 58.15%), and t ... | 1999 | 10592846 |
| effects of terminalia catappa seeds on sexual behaviour and fertility of male rats. | to evaluate the aphrodisiac potential of tenminalia catappa linn. seeds using a suspension of its kernel (ss) in 1% methyl cellulose in rats. | 2000 | 11225980 |
| antioxidant and hepatoprotective effects of punicalagin and punicalin on acetaminophen-induced liver damage in rats. | punicalagin and punicalin were isolated from the leaves of terminalia catappa l., a combretaceous plant distributed throughout tropical and subtropical beaches, which is used for the treatment of dermatitis and hepatitis. our previous studies showed that both of these compounds exert antioxidative activity. in this study, the antihepatotoxic activity of punicalagin and punicalin on acetaminophen-induced toxicity in the rat liver was evaluated. after evaluating the changes of several biochemical ... | 2001 | 11351354 |
| squalene content and antioxidant activity of terminalia catappa leaves and seeds. | squalene was identified by gas chromatography-mass spectrometry and high-performance liquid chromatography (hplc) spiking analyses in the supercritical co(2) extracts of freeze-dried abscisic leaves of terminalia catappa l. when the freeze-dried abscisic, senescent, mature, and immature leaves and seeds were subjected to supercritical co(2) extraction at 40 degrees c and 3000 psi and hplc quantitation, squalene contents were 12.29, 2.42, 1.75, 0.9, and 0% in the extracts and corresponding to 149 ... | 2002 | 12207472 |
| [experimental inoculation of terminalia catappa seedlings with an environmental isolate of cryptococcus neoformans var. gattii serotype c ]. | in 1997, our laboratory reported for the first time the isolation of cryptococcus neoformans var. gattii serotype c associated with almond tree (terminalia catappa) detritus. this finding led to a more detailed follow up of the association between the plant and the yeast. preliminary data have shown that survival of the yeast in almond trees seedlings goes beyond 100 days. the aim of the present study was to establish if under the conditions previously studied, c. neoformans var. gattii would re ... | 2002 | 12596450 |
| antimutagenicity of supercritical co2 extracts of terminalia catappa leaves and cytotoxicity of the extracts to human hepatoma cells. | natural antimutagens may prevent cancer and are therefore of great interest to oncologists and the public at large. phytochemicals are potent antimutagen candidates. when the ames test was applied to examine the antimutagenic potency of supercritical carbon dioxide (sc-co(2)) extracts of terminalia catappa leaves at a dose of 0.5 mg/plate, toxicity and mutagenicity were not detected. the antimutagenic activity of sc-co(2) extracts increased with decreases of temperature (60, 50, and 40 degrees c ... | 2003 | 12769525 |
| antidiabetic activity of terminalia catappa linn fruits. | in view of alleged antidiabetic potential, effect of the petroleum ether, methanol, and aqueous extracts of terminalia catappa linn (combretaceae) fruit, on fasting blood sugar levels and serum biochemical analysis in alloxan-induced diabetic rats were investigated. all the three extracts of terminalia catappa produced a significant antidiabetic activity at dose levels 1/5 of their lethal doses. concurrent histological studies of the pancreas of these animals showed comparable regeneration by me ... | 2003 | 12902049 |
| experimental infection of almond trees seedlings (terminalia catappa) with an environmental isolate of cryptococcus neoformans var. gattii, serotype c. | recently, our laboratory reported the isolation of cryptococcus neoformans var. gattii, serotype c for the first time from almond trees (terminalia catappa) detritus. the aim of the present study was to establish the survival of c. neoformans in almond trees seedlings. thirty seedlings were infected in the stems and samples were taken and processed at different times and by different techniques. no morphological alterations (macro or microscopic) were observed in the infected plants. however, c. ... | 2001 | 15487923 |
| [hepatoprotective effects of chloroform extract from leaf of terminalia catappa in relation to the inhibition of liver il-6 expression]. | to study the hepatoprotective effects of terminalia catappa chloroform extract (tcce) and its effects on il-6 gene over expression in liver of ccl4-treated mice. | 2003 | 15617504 |
| [protective effect of the extract of terminalia catappa leaves on acute liver injury induced by d-galn in mice]. | to study the hepatoprotective effect of the extract of terminala catappa leaves (tce) and the possible mechanisms underlying its protection on acute liver injury induced by d-galactosamine (d-galn). | 2004 | 15656141 |
| modifying effects of terminalia catappa on azoxymethane-induced colon carcinogenesis in male f344 rats. | the modifying effects of dietary administration of an herb, terminalia catappa (tc), were investigated on rat colon carcinogenesis induced by a carcinogen azoxymethane (aom). the number of aberrant crypt foci (acf) and beta-catenin accumulated crypts (bcacs) in the colon, and proliferating cell nuclear antigen (pcna) labelling index in the colonic epithelium were examined in a total of 36 male f344 rats. all animals were randomly divided into five experimental groups (4-10 rats in each group). a ... | 2005 | 15785313 |
| antibacterial screening of some peruvian medicinal plants used in callería district. | nine ethanol extracts of brunfelsia grandiflora (solanaceae), caesalpinia spinosa (caesalpiniaceae), dracontium loretense (araceae), equisetum giganteum (equisetaceae), maytenus macrocarpa (celastraceae), phyllanthus amarus (euphorbiaceae), piper aduncum (piperaceae), terminalia catappa (combretaceae), and uncaria tomentosa (rubiaceae), medicinal plants traditionally used in calleria district for treating conditions likely to be associated with microorganisms, were screened for antimicrobial act ... | 2005 | 15894143 |
| [environmental distribution of cryptococcus neoformans in the department of cundinamarca-colombia]. | cryptococcus neoformans is an opportunistic fungal pathogen that could cause infection in patients with immunodeficiency and healthy patients. the aids epidemic has shown the importance of studying the ecology and epidemiology of this fungus. the aim of this investigation was to determine if there was a relationship between the environmental distribution of the different varieties of c. neoformans and the climate zones in two transects located in department of cundinamarca, in colombia. for the ... | 2005 | 16107166 |
| effective protection of terminalia catappa l. leaves from damage induced by carbon tetrachloride in liver mitochondria. | the protective effects of chloroform extracts of terminalia catappa l. leaves (tcce) on carbon tetrachloride (ccl4)-induced liver damage and the possible mechanisms involved in the protection were investigated in mice. we found that increases in the activity of serum aspartate aminotransferase and alanine aminotransferase and the level of liver lipid peroxidation (2.0-fold, 5.7-fold and 2.8-fold) induced by ccl4 were significantly inhibited by oral pretreatment with 20, 50 or 100 mg/kg of tcce. ... | 2006 | 16169207 |
| mechanism underlying mitochondrial protection of asiatic acid against hepatotoxicity in mice. | asiatic acid (aa) is one of the triterpenoid components of terminalia catappa l., which has antioxidative, anti-inflammatory and hepatoprotective activity. this research focused on the mitochondrial protection of aa against acute liver injury induced by lipopolysaccharide (lps) and d-galactosamine (d-galn) in mice. it was found that pretreatment with 25, 50 or 100 mg kg(-1) aa significantly blocked the lps + d-galn-induced increase in both serum aspartate aminotransferase (sast) and serum alanin ... | 2006 | 16451751 |
| female-biased attraction of oriental fruit fly, bactrocera dorsalis (hendel), to a blend of host fruit volatiles from terminalia catappa l. | coupled gas chromatography-electroantennogram detection (gc-ead) analysis of volatiles from tropical almond fruit, terminalia catappa l., revealed 22 compounds that were detected by antennae of oriental fruit fly females, bactrocera dorsalis (hendel). both solid-phase microextraction (spme) and porapak q were used for sampling odors in fruit headspace, with spme collections producing larger ead responses from a greater number of compounds. geranyl acetate and methyl eugenol elicited the largest ... | 2006 | 17082987 |
| antioxidant and hepatoprotective actions of medicinal herb, terminalia catappa l. from okinawa island and its tannin corilagin. | the antioxidant and hepatoprotective actions of terminalia catappa l. collected from okinawa island were evaluated in vitro and in vivo using leaves extract and isolated antioxidants. a water extract of the leaves of t. catappa showed a strong radical scavenging action for 1,1-diphenyl-2-picrylhydrazyl and superoxide (o(2)(.-)) anion. chebulagic acid and corilagin were isolated as the active components from t. catappa. both antioxidants showed a strong scavenging action for o(2)(.-) and peroxyl ... | 2007 | 17293097 |
| angiotensin-converting enzyme inhibition by brazilian plants. | the potential antihypertensive activity of brazilian plants was evaluated in vitro by its ability to inhibit the angiotensin-converting enzyme (ace). forty-four plants belonging to 30 families were investigated. plants were selected based on their popular use as antihypertensive and/or diuretics. the following plants presented significant ace inhibition rates: calophyllum brasiliense, combretum fruticosum, leea rubra, phoenix roebelinii and terminalia catappa. | 2007 | 17513067 |
| host breadth and parasitoids of fruit flies (anastrepha spp.) (diptera: tephritidae) in puerto rico. | twenty fruit species representing 12 families were collected from various regions in western puerto rico and monitored for the emergence of anastrepha spp. pupae. we collected 14,154 tephritid pupae from 16 fruit species representing 10 families. the relative infestations of these fruits (pupae per kilogram of fruit) were recorded. recorded host ranges were not in complete agreement with those reported in the literature. this host-use pattern should give pause to regulators of fruit importation ... | 2008 | 18348802 |
| [feeding habits of the squirrel sciurus variegatoides (rodentia: sciuridae) in the nicoya peninsula, costa rica]. | food items consumed by the squirrel sciurus variegatoides atrirufus were determined in an agricultural setting in the nicoya peninsula (9 degrees 47' n, 84 degrees 56' w), costa rica, where two life zones (premontane moist forest basal belt transition, and tropical dry forest) predominate. by analyzing the gut contents of 120 squirrels, from february 1987 through january 1988, it was determined that coconut (cocos nucifera), indian almond (terminalia catappa) and flamboyant (delonix regia) were ... | 2006 | 18494334 |
| antimicrobial activity of terminalia catappa, manilkara zapota and piper betel leaf extract. | aqueous and methanol extract of the leaves of terminalia catappa l., manilkara zapota l. and piper betel l. were evaluated for antibacterial activity against 10 gram positive, 12 gram negative bacteria and one fungal strain, candida tropicalis. piperacillin and gentamicin were used as standards for antibacterial assay, while fluconazole was used as standard for antifungal assay. the three plants showed different degree of activity against the microorganisms investigated. the methanolic extract w ... | 2008 | 20046756 |
| effects of aspergillus niger-fermented terminalia catappa seed meal-based diet on selected enzymes of some tissues of broiler chicks. | effects of aspergillus niger-fermented terminalia catappa seed meal-based diet on the activities of alkaline phosphatase (alp), alanine transaminase (alt), aspartate transaminase (ast) and gamma-glutamate transferase (gamma-gt) in the crop, small intestine, gizzard, heart, liver and serum of broiler chicks were investigated. milled t. catappa seed was inoculated with spores of a.niger (2.21 x 10(4) spores per ml) for 3 weeks. forty-five day-old broiler chicks weighing between 27.62 and 36.21 g, ... | 2010 | 20170700 |
| the diversity of antibacterial compounds of terminalia species (combretaceae). | the antibacterial activity of acetone, hexane, dichloromethane leaf extract of five terminalia species (terminalia alata heyne ex roth., terminalia arjuna (roxb.) wt. and am., terminalia bellerica (gaertn.) roxb., terminalia catappa l. and terminalia chebula retz.) were tested by agar-well-diffusion method against human pathogens e. coli, pseudomonas aeruginosa, bacillus subtilis, staphylococcus aureus and staphylococcus epidermidis. the rf values and relative activities of separated compounds w ... | 2009 | 20180323 |
| in vitro antiplasmodial activity and toxicity assessment of some plants from nigerian ethnomedicine. | context: the emergence and spread of plasmodium falciparum-resistant parasites to nearly all available antimalarial drugs pose a threat to malaria control and necessitates the need to continue the search for new effective and affordable drugs. ethnomedicine has been shown to be a potential source of antimalarial compounds or source of template for the synthesis of novel antimalarial molecules. objective: the antiplasmodial activity and toxicity assessment of 30 plant extracts from eight medicina ... | 2011 | 20738218 |
| inhibitory effects of terminalia catappa on uvb-induced photodamage in fibroblast cell line. | this study investigated whether terminalia catappa l. hydrophilic extract (tclw) prevents photoaging in human dermal fibroblasts after exposure to uvb radiation. tclw exhibited dpph free radical scavenging activity and protected erythrocytes against aaph-induced hemolysis. in the gelatin digestion assay, the rates of collagenase inhibition by tcl methanol extract, tclw, and its hydrolysates were greater than 100% at the concentration of 1 mg/ml. we found that serial dilutions of tclw (10-500 μg/ ... | 2010 | 20981325 |
| antiplasmodial activity of new caledonia and vanuatu traditional medicines. | with the emergence of strains multiresistant to antimalarial drugs, the search for new active molecules remains a priority. ethnopharmacology appears to be a good method of selection in such investigations. | 2011 | 21284535 |
| tannin-rich fraction from terminalia catappa inhibits quorum sensing (qs) in chromobacterium violaceum and the qs-controlled biofilm maturation and lasa staphylolytic activity in pseudomonas aeruginosa. | the study aimed to test the activity of terminalia catappa l. against bacterial quorum sensing (qs) in order to provide a potential scientific basis for the traditional use of leaf extracts of this plant as an antiseptic. | 2011 | 21291979 |
| effect of terminalia catappa fruit meal fermented by aspergillus niger as replacement of maize on growth performance, nutrient digestibility, and serum biochemical profile of broiler chickens. | a feeding experiment was conducted to investigate the effect of fermented terminalia catappa fruit meal (ftcm) with aspergillus niger as replacement for maize on broiler growth performance, nutrient digestibility, and serum biochemical constituents. dietary maize was replaced by ftcm at 0, 20, 40, 60, or 80%. one hundred and eighty one-day-old shaver broiler chicks were randomly allocated to the five dietary treatments, three replicate groups of twelve chicks each for a 42-day period. there was ... | 2010 | 21350670 |
| isolation and evaluation of a polysaccharide from prunus amygdalus as a carrier for transbuccosal delivery of losartan potassium. | an oral buccoadhesive drug delivery system for losartan potassium using a hydrophilic polysaccharide, isolated from prunus amygdalaus (badam gum), was developed and evaluated for its potential to overcome the drawbacks associated with the conventional drug therapy. the results of the study indicate that the isolated polysaccharide has good physicochemical and morphological characteristics and is suitable for use as a mucoadhesive sustain release polymer in pharmaceutical dosage forms, to allevia ... | 2011 | 21392523 |
| antitrypanosomal activity of some medicinal plants from nigerian ethnomedicine. | human african trypanosomiasis is a neglected tropical disease with complex clinical presentation, diagnosis, and difficult treatment. the available drugs for the treatment of trypanosomiasis are old, expensive, and less effective, associated with severe adverse reactions and face the problem of drug resistance. this situation underlines the urgent need for the development of new, effective, cheap, and safe drugs for the treatment of trypanosomiasis. the search for new antitrypanosomal agents in ... | 2011 | 21789586 |
| evaluation of the antioxidant and hepatoprotective activity of terminalia catappa. | the free radical scavenging and antihepatotoxic activity from terminalia catappa was studied. treatment with t. catappa water extracts showed antihepatotoxic activity against ccl4-induced toxicity in the rat liver that was tested. the crude drug also exhibited anti-oxidant effects in fecl2-ascorbic acid induced lipid peroxidation in the rat liver homogenate. moreover, the superoxide radical scavenger effect of t. catappa was demonstrated using electron spin resonance (esr) and spintrapping techn ... | 1997 | 9288361 |
| isolation of genomic dna suitable for community analysis from mature trees adapted to arid environment. | isolation of intact and pure genomic dna (gdna) is essential for many molecular biology applications. it is difficult to isolate pure dna from mature trees of hot and dry desert regions because of the accumulation of high level of polysaccharides, phenolic compounds, tannins etc. we hereby report the standardized protocol for the isolation and purification of gdna from seven ecologically and medically important tree species of combretaceae viz. anogeissus (anogeissussericea var. nummularia, anog ... | 2011 | 21827837 |
| folk medicine in the northern coast of colombia: an overview. | traditional remedies are an integral part of colombian culture. here we present the results of a three-year study of ethnopharmacology and folk-medicine use among the population of the atlantic coast of colombia, specifically in department of bolívar. we collected information related to different herbal medicinal uses of the local flora in the treatment of the most common human diseases and health disorders in the area, and determined the relative importance of the species surveyed. | 2011 | 21939522 |
| [presumptive identification of cryptococcus gattii isolated from terminalia catappa in montería city, córdoba, colombia]. | the members of the cryptococcus neoformans species complex are responsible for cryptococcosis in animals and humans. human infection is thought to be acquired by inhalation of airborne propagules from an environmental source; therefore it is greatly important to study their habitat. objective: to determine the ecological relationship of cryptococcus gattii with terminalia catappa trees present in urban areas of montería city in colombia. | 2011 | 23437518 |
| survival of listeria monocytogenes, and other food spoilage microbes in vacuum packaged west african soft cheese 'wara'. | 'wara' soft cheese is traditionally produced in nigeria and has a poor microbial quality. this study assessed the survivability of listeria monocytogenes and other food spoilage microbes (enterobacteriacea, molds and yeasts) in vacuum packaged soft cheese treated independently with carica papaya (vcpc), terminalia cattapa (vtcc) crude extracts, nisin (vnc), and the combination of these three treatments (v+3) stored at 15 degrees c and 28 degrees c for a three week storage period. vacuum packagin ... | 2012 | 23678645 |
| an updated review of terminalia catappa. | terminalia catappa linn. is known for its nutritional fruit and possesses medicinal benefits as well. this is a comprehensive review of the phytoconstituents and pharmacological benefits. t. catappa has been recognized for its medicinally essential phytoconstituents, such as phenol, flavonoid, and carotenoid. numerous pharmacological investigations have confirmed this plant's ability to exhibit antimicrobial, anti-inflammatory, antidiabetic, antioxidant, hepatoprotective, and anticancer activiti ... | 2015 | 26392705 |
| potential application of extracts from indian almond (terminalia catappa linn.) leaves in siamese fighting fish (betta splendens regan) culture. | indian almond (terminalia catappa linn.) leaves with green and red coloration were tested for bactericidal activity with pathogenic bacteria and their acute toxicity to siamese fighting fish (betta splendens regan). powder of indian almond leaves was extracted with water at the ratio of 1:10 (w/v) and then freeze-dried to a dry powder. bactericidal efficacy was tested against 28 isolates of pathogenic bacteria (aeromonas hydrophila, edwardsiella tarda, enterobacter spp., plesiomonas shigelloides ... | 2012 | 23885412 |
| application of diverse natural polymers in the design of oral gels for the treatment of periodontal diseases. | the objective of this study was to prepare periodontal gels using natural polymers such as badam gum, karaya gum and chitosan. these gels were tested for their physical and biochemical properties and assessed for their antibacterial activity against aggregatibacter actinomycetemcomitans and streptococcus mutans, two pathogens associated with periodontal disease. badam gum, karaya gum and chitosan were used to prepare gels of varying concentrations. moxifloxacin hydrochloride, a known antimicrobi ... | 2017 | 28144851 |
| cryptococcosis in atlántico, colombia: an approximation of the prevalence of this mycosis and the distribution of the etiological agent in the environment. | cryptococcosis is an invasive disease acquired by inhalation of infectious propagules from the environment. currently, compulsory notification of the spread of this disease is not required in colombia. however, reporting of human immunodeficiency virus (hiv)/acquired immune deficiency syndrome cases to the national surveillance system has suggested that there is a growing population at risk of contracting cryptococcosis. few studies have described the occurrence of cryptococcosis in colombia. th ... | 2015 | 26516968 |
| long-term survival of cryptococcus neoformans and cryptococcus gattii in stored environmental samples from colombia. | both cryptococcus neoformans and cryptococcus gattii have been isolated from a variety of environmental sources in colombia. | 2015 | 25725529 |
| preparation and properties of cellulose nanocomposite films with in situ generated copper nanoparticles using terminalia catappa leaf extract. | in the present work, copper nanoparticles (cunps) were in situ generated inside cellulose matrix using terminalia catappa leaf extract as a reducing agent. during this process, some cunps were also formed outside the matrix. the cunps formed outside the matrix were observed with transmission electron microscope (tem) and scanning electron microscope (sem). majority of the cunps formed outside the matrix were in the size range of 21-30nm. the cellulose/cunp composite films were characterized by f ... | 2017 | 27984140 |
| antimicrobial activity of extracts of terminalia catappa root. | the effect against bacteria of petroleum ether (60-80 degrees c), chloroform and methanolic extract of dried root of terminalia catappa linn. (combrataceae) was employed by cup plate agar diffusion method. the chloroform extract showed prominent antimicrobial activity against s. aureus and e. coli as compared to other tested microorganisms, while petroleum ether extract was devoid of antimicrobial activity. the methanolic: extract exhibited mic of 0.065 mg/ml against e. coli. and chloroform extr ... | 2002 | 12649950 |
| the anthelmintic effects of the ethanol extract of terminalia catappa l. leaves against the ruminant gut parasite, fischoederius cobboldi. | presently, no effective anthelmintic drugs have been used to treat and control paramphistomosis, a severe disease of ruminants. in this study, we have investigated the in vitro anthelmintic effect of the leaves of terminalia catappa l. crude extract (tcce) and albendazole (abz) on adult fischoederius cobboldi after incubating the flukes in rpmi-1640 medium containing the tcce at various doses and times. the tcce-treated flukes at all dosages exhibited rapid decrease of motility, and the relative ... | 2016 | 26831432 |
| terminalia catappa l.: a medicinal plant from the caribbean pharmacopeia with anti-helicobacter pylori and antiulcer action in experimental rodent models. | terminalia catappa l. (combretaceae) is a medicinal plant listed as a pharmacopeia vegetable from caribbean to treat gastritis. the objective of this study was to evaluate the gastroprotective and healing effect of the aqueous fraction (fraq) obtained from the leaves of terminalia catappa and to determine the antiulcer mechanism of action in experimental rodent models and its activity to helicobacter pylori. | 2015 | 25460589 |
| exploration of phytochemicals found in terminalia sp. and their antiretroviral activities. | the human immunodeficiency virus (hiv) infects cells of the immune system and destroys their function. approximately, 2 million people die every year from hiv as reported by the world health organization. hiv/aids is difficult to treat as the virus continuously develops resistance to drugs being developed. approach is now turning toward natural products for the development of anti-hiv drugs. although hiv/aids is not a new disease, but research based on plant-derived products is still under clini ... | 2017 | 28082788 |
| plants promote mating and dispersal of the human pathogenic fungus cryptococcus. | infections due to cryptococcus are a leading cause of fungal infections worldwide and are acquired as a result of environmental exposure to desiccated yeast or spores. the ability of cryptococcus to grow, mate, and produce infectious propagules in association with plants is important for the maintenance of the genetic diversity and virulence factors important for infection of animals and humans. in the western united states and canada, cryptococcus has been associated with conifers and tree spec ... | 2017 | 28212396 |
| synergism among volatile organic compounds resulting in increased antibiosis in oidium sp. | oidium sp. has been recovered as an endophyte in terminalia catappa (tropical chestnut) in costa rica. the volatile organic compounds (vocs) of this organism uniquely and primarily consist of esters of propanoic acid, 2-methyl-, butanoic acid, 2-methyl-, and butanoic acid, 3-methyl-. the vocs of oidium sp. are slightly inhibitory to many plant pathogenic fungi. previous work on the vocs of muscodor albus demonstrated that besides esters of small organic acids, a small organic acid and a naphthal ... | 2008 | 18422630 |
| beneficial effect of medicinal plants on the contractility of post-hypoxic isolated guinea pig atria - potential implications for the treatment of ischemic-reperfusion injury. | context ischemic-reperfusion injury is accompanied by a decreased contractility of the myocardium. positive-inotropic agents have proven useful for treating this condition but may exert serious side-effects. objective in this study, aqueous preparations from abelmoschus esculentus l. moench (malvaceae), annona muricata l. (annonaceae), bixa orellana l. (bixaceae), cecropia peltata l. (moraceae), erythrina fusca lour. (fabaceae), psidium guajava l. (myrtaceae) and terminalia catappa l. (combretac ... | 2016 | 26730936 |
| biofabrication of ag nanoparticles using sterculia foetida l. seed extract and their toxic potential against mosquito vectors and hela cancer cells. | a one-step and eco-friendly process for the synthesis of silver-(protein-lipid) nanoparticles (ag-pl nps) (core-shell) has been developed using the seed extract from wild indian almond tree, sterculia foetida (l.) (sterculiaceae). the reaction temperature played a major role in controlling the size and shell formation of nps. the amount of nps synthesized and qualitative characterization was done by uv-vis spectroscopy and transmission electron microscopy (tem), respectively. tem studies exhibit ... | 2014 | 24863217 |
| aphrodisiac activity of polyherbal formulation in experimental models on male rats. | to investigate the aphrodisiac potential of polyherbal formulations prepared from different parts of tribulus terrestris, curculigo orchioides, allium tuberosum, cucurbita pepo, elephant creeper, mucuna pruriens, and terminalia catappa in albino rats in specified ratio as suspension. | 2014 | 24761115 |
| sodium metabisulfite-induced polymerization of sickle cell hemoglobin incubated in the extracts of three medicinal plants (anacardium occidentale, psidium guajava, and terminalia catappa). | the exploitation and utilization of vast varieties of herbal extracts may serve as alternative measures to deter aggregation of deoxygenated sickle cell hemoglobin (deoxyhbs) molecules. | 2011 | 21716622 |
| membrane stability of sickle erythrocytes incubated in extracts of three medicinal plants: anacardium occidentale, psidium guajava, and terminalia catappa. | many reports showed that medicinal plant extracts cause alterations on the shape and physiology of erythrocytes. | 2011 | 21716621 |
| host range and distribution of fruit-infesting pestiferous fruit flies (diptera, tephritidae) in selected areas of central tanzania. | the host range of major fruit fly pests in central tanzania was evaluated from october 2004 to october 2006. samples of 48 potential hosts were collected and incubated for fruit fly emergence. bactrocera invadens was the dominant species in incidence expressed as the ratio of infested to total number samples collected, as well as infestation rate, expressed as number of flies emerging per unit weight. eight new host fruits are reported. infestation by native pests, such as ceratitis capitata and ... | 2009 | 19323850 |
| beach almond (terminalia catappa, combretaceae) seed production and predation by scarlet macaws (ara macao) and variegated squirrels (sciurus variegatoides). | knowledge of ecological impacts of exotic beach almond (terminalia catappa) in the central pacific of costa rica are little known, but studies have found this species to be a potentially important food source for endangered scarlet macaws (ara macao). in this study, reproductive phenology and seed predation by variegated squirrels (sciurus variegatoides) and scarlet macaws were measured during march and april 2011 on beaches of central pacific coastal costa rica. seed productivity and predation ... | 2014 | 25412525 |
| nutritional composition of fruits selected by long-tailed macaques (macaca fascicularis) in kuala selangor, malaysia. | proximate analysis of twelve species of fruits commonly consumed by long-tailed macaques (macaca fascicularis), i.e., arenga pinnata, areca catechu, terminalia catappa, elaeis guineensis, lagerstroemia tomentosa, mangifera indica, cascabela thevetia, muntingia calabura, musa sp., artocarpus heterophyllus, ficus tinctoria ssp. gibbosa and ficus microcarpa, was conducted with the specific objective to determine the nutritional composition of the foodstuffs of long-tailed macaques. the results show ... | 2017 | 28228918 |
| folk medicine terminalia catappa and its major tannin component, punicalagin, are effective against bleomycin-induced genotoxicity in chinese hamster ovary cells. | terminalia catappa l. is a popular folk medicine for preventing hepatoma and treating hepatitis in taiwan. in this paper, we examined the protective effects of t. catappa leaf water extract (tce) and its major tannin component, punicalagin, on bleomycin-induced genotoxicity in cultured chinese hamster ovary cells. pre-treatment with tce or punicalagin prevented bleomycin-induced hgprt gene mutations and dna strand breaks. tce and punicalagin suppressed the generation of bleomycin-induced intrace ... | 2000 | 10773401 |
| bactrocera invadens (diptera: tephritidae), a new invasive fruit fly pest for the afrotropical region: host plant range and distribution in west and central africa. | in 2003, the invasive fruit fly bactrocera invadens drew, tsuruta & white (diptera: tephritidae) (drew et al. 2005), of possible sri lankan origin, has been detected in the east and about 1 yr later in west africa. in regular surveys in benin and cameroon covering 4 yr, samples from 117 plant species across 43 families have been obtained. incubation of field-collected fruits demonstrate that in west and central africa (wca) b. invadens is highly polyphagous, infesting wild and cultivated fruits ... | 2011 | 22251685 |
| evaluation of the antioxidant activity of environmental plants: activity of the leaf extracts from seashore plants. | the antioxidant activity of the methanolic extracts of the leaves of 39 plant species was examined. these leaves were collected from the plants growing on subtropical seashores. the activity was evaluated by three kinds of assay methods, which included the dpph radical scavenging assay, linoleic acid oxidation assay, and oxidative cell death assay. two extracts from excoecaria agallocha and terminalia catappa showed remarkably potent activity in all assay systems. the hplc analysis of the extrac ... | 1999 | 10564049 |
| a new species of japanagromyza sasakawa (diptera: agromyzidae) from the brazilian amazon with notes on biology. | japanagromyza sasakawai sp. n. is described from the brazilian amazon, based on the male, female, third instar larva and puparium. this species is a leaf-miner of terminalia catappa l. (combretaceae), which is an introduced plant from the old world tropics used in brazil as an ornamental. the male aedeagus of j. sasakawai sp. n. differs from other species mainly in having the mesophallus covered with many spine-like processes. this is the third record of japanagromyza sasakawa in brazil and firs ... | 2015 | 25781139 |
| terminalia catappa attenuates urokinase-type plasminogen activator expression through erk pathways in hepatocellular carcinoma. | the survival rate of malignant tumors, and especially hepatocellular carcinoma (hcc), has not improved primarily because of uncontrolled metastasis. in our previous studies, we have reported that terminalia catappa leaf extract (tce) exerts antimetastasis effects on hcc cells. however, the molecular mechanisms of urokinase-type plasminogen activator (u-pa) in hcc metastasis have not been thoroughly investigated, and remain poorly understood. | 2014 | 24886639 |
| description of a new species of terminalichus (acari: trombidiformes: tenuipalpidae) from china. | a new species terminalichus sanya xu & fan sp. nov. (acari: tenuipalpidae) on terminalia catappa l. (combretaceae) from china is described and illustrated. the ontogenetic changes in ventral and leg chaetotaxy on the female, deutonymph, protonymph and larva are presented. the generic definition of terminalichus is updated and a key to the world species is provided. | 2014 | 24872294 |
| characterization and quantification of compounds in the hydroalcoholic extract of the leaves from terminalia catappa linn. (combretaceae) and their mutagenic activity. | terminalia is a genus of combretaceous plants widely distributed in tropical and subtropical regions. thus, the aim of this study was to quantify the majority compounds of the hydroalcoholic extract (7 : 3, v/v) of the leaves from t. catappa by hplc-pda, chemically characterize by hyphenated techniques (hplc-esi-it-ms(n)) and nmr, and evaluate its mutagenic activity by the salmonella/microsome assay on s. typhimurium strains ta98, ta97a, ta100, and ta102. the quantification of analytes was perfo ... | 2014 | 24734110 |
| analysis of sea almond (terminalia catappa) cracking sites used by wild burmese long-tailed macaques (macaca fascicularis aurea). | nut-cracking is shared by all non-human primate taxa that are known to habitually use percussive stone tools in the wild: robust capuchins (sapajus spp.), western chimpanzees (pan troglodytes verus), and burmese long-tailed macaques (macaca fascicularis aurea). despite opportunistically processing nuts, burmese long-tailed macaques predominantly use stone tools to process mollusks in coastal environments. here, we present the first comprehensive survey of sea almond (terminalia catappa) nut-crac ... | 2017 | 28056164 |
| the in vitro anthelmintic activity of the ethanol leaf extracts of terminalia catappa l. on fasciola gigantica. | at present, there are no medicinal plant extracts currently available for treatment and control of fasciolosis. the present work could provide, for the first study, conclusions on the in vitro fasciolicidal properties of the ethanol extract of terminalia catappa l. (tcce) leaves against adult fasciola gigantica after incubation with rpmi-1640 medium containing the tcce at various concentrations and times when compared with triclabendazole (tcz). the relative motility and survival index values of ... | 2017 | 28805167 |
| physicochemical properties of malaysian-grown tropical almond nuts (terminalia catappa). | the seeds of terminalia catappa from malaysia were analyzed for their physicochemical properties. the following values were obtained: moisture 6.23 ± 0.09 %, ash 3.78 ± 0.04 %, lipid 54.68 ± 0.14 %, protein 17.66 ± 0.13 %, total dietary fibre 9.97 ± 0.08 %, carbohydrate 7.68 ± 0.06 %, reducing sugar 1.36 ± 0.16 %, starch 1.22 ± 0.15 %, caloric value 593.48 ± 0.24 %. studies were also conducted on amino acid profile and free fatty acid composition of the seed oil. results revealed that glutamic a ... | 0 | 26396409 |
| effect of roasting conditions on color development and fourier transform infrared spectroscopy (ftir-atr) analysis of malaysian-grown tropical almond nuts (terminalia catappa l.). | proper roasting is crucial to flavor, color, and texture development in the final product. in recent years, several research studies have been carried out to establish the best optimum roasting conditions for some common edible nuts such as; hazelnut, peanut, and pistachio nut. although roasting is an important process for nuts and oilseeds, there is little or no information on the development of color, aroma, and textural changes in terminalia catappa nuts during roasting. | 0 | 25317204 |
| antimicrobial polyphenols from small tropical fruits, tea and spice oilseeds. | the polyphenolic fractions of fruits: terminalia catappa, carissa carandas, ziziphus nummularia; spice oilseeds: thymol, mustard, fenugreek and poppy seeds; and herb: green and black teas were analyzed for their total phenolics, flavonoids and antimicrobial potential. all fractions from fruits, except anthocyanin of c. carandas, displayed substantial antibacterial activity in accordance to their phenolic contents, the difference in activity being quite significant (p < 0.05), highest for t. cata ... | 2014 | 23703103 |
| an eels-based study of the effects of pyrolysis on natural carbonaceous materials used for activated charcoal preparation. | electron energy-loss spectroscopy (eels) has been used to characterize the electronic structure of charcoal phases at the nanoscale, thus demonstrating that the technique can be applied to environmental science. activated charcoal is extensively used to remove pollutants from liquid and gaseous sewage. it is mainly obtained by activation of coke or charcoal produced from ligneous precursors. the present study concerns the use of by-products of local caribbean agriculture, such as sugar cane baga ... | 2003 | 12694416 |
| terminalia catappa: chemical composition, in vitro and in vivo effects on haemonchus contortus. | haemonchus contortus is the most important nematode in small ruminant systems, and has developed tolerance to all commercial anthelmintics in several countries. in vitro (egg hatch assay) and in vivo tests were performed with a multidrug strain of haemonchus contortus using terminalia catappa leaf, fruit pulp, and seed extracts (in vitro), or pulp and seed powder in lambs experimentally infected with h. contortus. crude extracts from leaves, fruit pulp and seeds obtained with 70% acetone were ly ... | 2017 | 28969774 |
| effect of carboxymethylation on rheological and drug release characteristics of terminalia catappa gum. | the carboxymethylation of galactomannans, arabinogalactans, arbinoxylan, etc is known to modify solubility, swelling index, rheological behaviour, powder characteristics, etc. therefore, an attempt had been made to study the effect of carboxymethylation on terminalia catappa (tc) gum. for this, modified williamson synthesis reaction was utilized employing quality by design (qbd) approach. grafting of carboxymethyl group on terminalia catappa was confirmed by atr-ftir, h1nmr and dsc analyses. the ... | 2017 | 28917923 |
| effects of an oil spill on the leaf anatomical characteristics of a beach plant (terminalia catappa l.). | this study investigated the short-term impacts of an oil spill on the leaf anatomical structures of terminalia catappa l. from crude oil leakage in rayong province, thailand, in 2013. approximately 3 weeks after the oil spill, leaves of t. catappa were collected along the coastline of rayong from one affected site, five adjacent sites, and a control site. slides of the leaf epidermis were prepared by the peeling method, while leaf and petiole transverse sections were prepared by paraffin embeddi ... | 2017 | 28776293 |
| phytochemical characterization of terminalia catappa linn. extracts and their antifungal activities against candida spp. | terminalia catappa linn bark is used to treat dysentery by various populations in southeast asian countries, and its leaves have also been used in traditional medicine to treat hepatitis in india and the philippines. here, the antifungal actions of crude hydro-alcoholic extract (tche) and fractions from t. catappa leaves were assessed via the agar diffusion and microdilution tests on candida reference strains and clinical isolates from patients with acquired immunodeficiency syndrome (aids). add ... | 2017 | 28443078 |
| optimization of the enzymatic synthesis of biodiesel from terminalia cattapa l. kernel oil using response surface methodology. | the synthesis of biodiesel using terminalia cattapa l. (local language: ketapang) kernel oil and ethanol has been conducted. the effect of variable parameters of synthesis includes reaction time (3-7 h), temperature (35-60°c), amount of enzyme (0.1-0.3 g) and substrate molar ratio (ketapang kernel oil to ethanol, 1:1-1:3) were studied. response surface methodology based on a five-level and four-variable central composite rotatable design were used to evaluate the interactive effects of the sinth ... | 2017 | 28190806 |
| antidepressant like effects of hydrolysable tannins of terminalia catappa leaf extract via modulation of hippocampal plasticity and regulation of monoamine neurotransmitters subjected to chronic mild stress (cms). | terminalia catappa l. belonging to combretaceae family is a folk medicine, known for its multiple pharmacological properties, but the neuro-modulatory effect of tc against chronic mild stress was seldom explored. the present study was designed to elucidate potential antidepressant-like effect of terminalia cattapa (leaf) hydro-alcoholic extract (tc) by using cms model for a period of 7 weeks. identification of hydrolysable tannins was done by using lc-ms. after the cms exposure, mice groups were ... | 2017 | 28012396 |
| proposed mechanisms of terminalia catappa in hyperglycaemia and associated diabetic complications. | terminalia catappa has shown potent antidiabetic activity in the past; however, the exact molecular mechanisms by which it acts have not been elucidated. this review aims at exploring several hypotheses which have been proposed to explain its mechanism of action, including reduction in oxidative stress, inflammation, angiogenesis, lipid profile correction and direct hypoglycaemic actions. | 2017 | 28000229 |
| antiinflammatory and immunomodulatory activity of an ethanolic extract from the stem bark of terminalia catappa l. (combretaceae): in vitro and in vivo evidences. | terminalia catappa linn (combretaceae) is a medicinal plant with anti-inflammatory, anti-diarrhoeal and antioxidant properties, frequently found in tropical regions. considering its characteristics, it could be useful for the treatment of inflammatory bowel disease, which is associated with inflammation, oxidative stress and an immune dysfunction. thus this study evaluates the immunomodulatory properties and the intestinal anti-inflammatory effect of an ethanolic extract of the stem bark of t. c ... | 2016 | 27452660 |
| corrigendum to "terminalia catappa exerts antimetastatic effects on hepatocellular carcinoma through transcriptional inhibition of matrix metalloproteinase-9 by modulating nf-κb and ap-1 activity". | [this corrects the article doi: 10.1155/2012/595292.]. | 2015 | 26692372 |
| in vitro antimicrobial activity of crude ethanol extracts and fractions of terminalia catappa and vitex doniana. | the spread of microorganisms resistant to some antimicrobial agents necessitates the need to search for novel and effective antimicrobial agents. in this study, the antimicrobial activity of terminalid catappa linn. (combretaceae) and vitex doniana sweet. (verbenaceae), two nigerian medicinal plants used in folk medicines for the management of various ailments related to microbial infections were evaluated. | 2015 | 26548112 |
| formulation of gastric floating system using bio-sourced terminalia catappa gum and in vivo evaluation. | a central composite design was applied to design a novel gastric floating drug delivery system comprising propranolol hcl in terminalia catappa gum and to evaluate the buoyancy, in vitro drug release behavior, and pharmacokinetic parameters. all formulations exhibited good buoyancy properties in vitro reflected by floating lag time of 1-110 sec, total floating time of 9-16 h and prolonged release behaviour (upto 12 h). statistically optimised formulation (pbgrso) was orally administered to human ... | 2016 | 26452534 |
| potent and synergistic extract combinations from terminalia catappa, terminalia mantaly and monodora tenuifolia against pathogenic yeasts. | mycoses caused by candida and cryptococcus species, associated with the advent of antifungal drug resistance have emerged as major health problems. improved control measures and innovative therapies are needed. this paper describes results from the screening of bio-guided fractionated extracts alone and combinations of terminalia catappa, terminalia mantaly and monodora tenuifolia harvested in cameroon. crude ethanolic, hydro-ethanolic and aqueous extracts and bio-guided fractions were screened ... | 2015 | 28930209 |
| the medicinal properties and phytochemistry of plants of the genus terminalia (combretaceae). | plants of the genus terminalia are amongst the most widely used plants for traditional medicinal purposes worldwide. many species are used for their antibacterial, antifungal, antiprotozoal, antiviral, antidiarrhoeal, analgesic, antimalarial, antioxidant, antiinflammatory and anticancer activities. wound healing and cardiovascular effects have also been credited to some species. many terminalia species have multiple beneficial effects for multiple diseases and ailments. indeed, the indian specie ... | 2015 | 26226895 |
| a new aromatic compound from the stem bark of terminalia catappa. | a new aromatic compound 3,4,5-trimethoxyphenyl-1-o-(4-sulfo)-β-d-glucopyranoside (1), in addition to two triterpenoid saponins (chebuloside ii, arjunoglucoside ii), two triterpenes (arjunolic acid and 3-betulinic acid) and sitosterol-3-o-β-d-glucopyranoside have been isolated from the barks of terminalia catappa. their structures have been established on the basis of spectroscopic techniques (1d/2d nmr) and ms. their cytotoxicity and antiinflammatory activity, together with the antioxidant capac ... | 2015 | 26197537 |
| the effect of thermal processing on protein quality and free amino acid profile of terminalia catappa (indian almond) seed. | the study examined the effect of various processing methods- boiling, drying and roasting- on the in vitro and in vivo protein digestibility and free amino acid profiles of terminalia catappa seed. moisture and crude protein of the various samples were determined. in vitro protein digestibility was determined after pepsin digestion. for the in vivo experiment, defatted t. catappa based diet was fed to 3 weeks old wistar rats for 4 weeks and compared with animals maintained on casein based and ni ... | 2015 | 26139937 |
| physicochemical properties of terminalia catappa seed oil as a novel dietary lipid source. | terminalia catappa linn (tc) is an ornamental tree planted extensively in many countries. it has been known for a long time that the seeds are edible but no research has focused on the realm of its use as food. our previous data showed that the seed contains high levels of oil content (600 g/kg) and possesses the optimum fatty acid balance indicated in fat dietary guidelines. this study aims to investigate the physical and chemical properties and the possibility of using tc seed oil as a new die ... | 2015 | 28911374 |
| colon specific drug delivery of tramadol hcl for chronotherapeutics of arthritis. | the objective of present work is to develop and evaluate a matrix system for chronotherapeutic delivery of centrally acting of opioid analgesic (tramadol hcl) to treat nocturnal symptoms of arthritis using almond gum as carrier. | 2017 | 25599032 |
| a validated high-performance liquid chromatography method for determination of tannin-related marker constituents gallic acid, corilagin, chebulagic acid, ellagic acid and chebulinic acid in four terminalia species from india. | a validated rapid hplc-pda method was developed for identification and quantification of five tannin-related constituents gallic acid (ga), corilagin (cl), chebulagic acid (cb), ellagic acid (ea) and chebulinic acid (cn) in the extracts prepared from the bark and fruits of four terminalia species available in india. the separation of the five analytes was achieved on an rp-18 column (4.6 × 250 mm, 5 µm) at 25°c using a solvent mixture comprising of acetonitrile and (0.05%) trifluoroacetic acid-w ... | 2015 | 25190275 |
| badam gum: a natural polymer in mucoadhesive drug delivery. design, optimization, and biopharmaceutical evaluation of badam gum-based metoprolol succinate buccoadhesive tablets. | applicability of natural polymers in pharmaceutical drug delivery. | 2016 | 24825493 |
| induction of foetal haemoglobin synthesis in erythroid progenitor stem cells: mediated by water-soluble components of terminalia catappa. | current novel therapeutic agents for the treatment of sickle cell anaemia (sca) focus on increasing foetal haemoglobin (hbf) levels in sca patients. unfortunately, the only approved hbf-inducing agent, hydroxyurea, has long-term unpredictable side effects. studies have shown the potential of plant compounds to modulate hbf synthesis in primary erythroid progenitor stem cells. we isolated a novel hbf-inducing terminalia catappa distilled water active fraction (tcdwf) from terminalia catappa leave ... | 2014 | 24470326 |
| evaluation of wound healing property of terminalia catappa on excision wound models in wistar rats. | wound is defined as the loss of breaking cellular and functional continuity of the living tissues. management of wounds is frequently encountered with different problems. drug resistance and toxicity hindered the development of synthetic antimicrobial agents with wound healing activity. many plants with potent pharmacological activities may offer better treatment options viz. terminalia chebula, terminalia bellirica and phyllanthus emblica formulations have shown healing activities on wounds.the ... | 2014 | 24132703 |
| antitumor and antioxidant status of terminalia catappa against ehrlich ascites carcinoma in swiss albino mice. | the present study was undertaken to evaluate the antitumor and antioxidant status of ethanol extract of terminalia catappa leaves against ehrlich ascites carcinoma (eac) in swiss albino mice. | 2015 | 24130380 |
| prospects for the use of municipal tree pruning wastes in particleboard production. | the purpose of this study was to evaluate the physical and mechanical properties of particleboard made with pruning wastes from ipê (tabebuia serratifolia) and chapéu-de-sol (terminalia catappa) trees. particleboards were prepared with both wood species, using all the material produced by grinding the pruning wastes. the particleboards had dimensions of 45 × 45 cm, a thickness of approximately 11.5 mm and an average density of 664 kg/m3. a urea-formaldehyde adhesive was used in the proportion of ... | 2013 | 23836102 |
| green analytical methodology using indian almond (terminalia catappa l.) leaf extract for determination of aluminum ion in waste water from ceramic factories. | the use of natural reagents from plant extracts for chemical analysis is one of the approaches in the development of low cost and environmentally friendly green analytical chemistry methodology. here, crude extract from indian almond (terminalia catappa l.) leaves was used for colorimetric determination of aluminum by monitoring the absorbance of the al(3+)-extract complex at 435 nm. dry leaves and freeze-dried fresh leaf extract can be kept for extended use. a simple flow injection analysis (fi ... | 2013 | 23749133 |
| terminalia catappa exerts antimetastatic effects on hepatocellular carcinoma through transcriptional inhibition of matrix metalloproteinase-9 by modulating nf-κb and ap-1 activity. | high mortality and morbidity rates for hepatocellular carcinoma (hcc) in taiwan primarily result from uncontrolled tumor metastasis. previous studies have identified that terminalia catappa leaf extracts (tce) exert hepatoprotective, antioxidative, antiinflammatory, anticancer, and antimetastatic activities. however, the effects of tce on hcc and the underlying molecular mechanisms of its activities have yet to be fully elucidated. the present study's findings demonstrate that tce concentration ... | 2012 | 23258989 |
| characterization and in vitro drug release studies of a natural polysaccharide terminalia catappa gum (badam gum). | the main objective of the present study is the physicochemical characterization of naturally available terminalia catappa gum (badam gum [bg]) as a novel pharmaceutical excipient and its suitability in the development of gastroretentive floating drug delivery systems (grfdds) to retard the drug for 12 h when the dosage form is exposed to gastrointestinal fluids in the gastric environment. as bg was being explored for the first time for its pharmaceutical application, physicochemical, microbiolog ... | 2012 | 23090110 |
| suppressive effects of the leaf of terminalia catappa l. on osteoclast differentiation in vitro and bone weight loss in vivo. | oral administration of terminalia catappa extract (tce; 1,000 mg/kg) for 5 wk suppressed bone weight loss and trabecular bone loss in ovariectomized mice. an in vitro experiment showed that tce (1.3-20 µg/ml) did not increase alkaline phosphatase activity, which would indicate osteoclast formation, in osteoblast-like 3t3-l1 cells. on the other hand, tce (12.5 µg/ml) markedly decreased the number of tartrate resistant acid phosphatase (trap)-positive multinucleated cells, which would indicate ost ... | 2012 | 22790571 |
| effect of terminalia catappa on lipid profile in transplanted fibrosarcoma in rats. | to evaluate the effect of an antitumor activity of terminalia catappa on lipid lowering activity in transplanted fibrosarcoma in wistar albino rats. methylcholantherene-induced fibrosarcoma was transplanted in rats. after 30(th) day when tumor became palpable, started the treatment of ethanolic extract of terminalia catappa by orally (250 and 500 mg/kg) for a period of 20 days. the blood sample was collected on 21(st) day, and the liver and the kidney were also removed for studying the lipid pro ... | 2012 | 22701253 |
| hydrolysable tannins of tropical almond show antifibrotic effects in tgf-β1-induced hepatic stellate cells. | persistent activation of hepatic stellate cells (hsc-t6) has been known to cause liver fibrosis. in this study, our objective was to investigate the effects of chebulagic acid and chebulinic acid, two hydrolysable tannins of tropical almond (terminalia chebula) fruits, on collagen synthesis and signal transduction in transforming growth factor-β1-stimulated hsc-t6 cells. the expression of smad2, smad3, smad4, collagen i(α1)/iii, and plasminogen activator inhibitor 1 (pai-1) mrnas was determined ... | 2011 | 21725979 |