| [activity of ethambutol, isoniazid and rifampicin on corynebacterium urealyticum and corynebacterium jeikeium]. | because corynebacteria and mycobacteria have walls of similar composition, it was of interest to test the effects on resistant corynebacteria of two agents with anti-wall effects, i.e., ethambutol (emb) and isoniazid (inh). rifampicin was also studied to extend previous data and clarify conflicting results in the literature. inh was not active in levels achieved in vivo with standard dosages. the minimal inhibitory concentration (mic) of emb was under serum levels for only three of 78 strains. a ... | 1992 | 1299816 |
| whipple's disease complicated by a retinal jarisch-herxheimer reaction: a case report. | a 36 year old white man was diagnosed as having whipple's disease after a prolonged illness of lethargy, night sweats, and weight loss associated with lymphadenopathy and splenomegaly. biopsy specimen of an inguinal lymph node confirmed the presence of periodic acid schiff positive macrophages and culture gave a pure growth of corynebacterium jeikeium. twelve hours after the introduction of oral co-trimoxazole and streptomycin the patient's condition deteriorated. he became confused, feverish, a ... | 1992 | 1371261 |
| three cases of opportunistic infection caused by propionic acid producing corynebacterium minutissimum. | propionic acid producing strains of corynebacterium minutissimum were isolated from three patients with opportunistic infections. one neutropenic patient was undergoing chemotherapy for prolymphocytic leukemia; the other two patients were undergoing hemodialysis and peritoneal dialysis respectively. an unusual feature of these three strains was their resistance to several antibiotics, which is seldom seen in diphtheroids other than corynebacterium jeikeium and cdc group d2. | 1992 | 1396773 |
| corynebacterium jeikeium meningitis and transverse myelitis in a neutropenic patient. | | 1992 | 1425720 |
| [bacteremia caused by corynebacterium jeikeium in an immunocompromised patient]. | | 1992 | 1489804 |
| in vitro activity of sparfloxacin and six reference antibiotics against gram-positive bacteria. | the in vitro activity of sparfloxacin, a new fluoroquinolone, was assessed against 234 gram-positive bacterial isolates by agar dilution (10(4) cfu/spot). sparfloxacin activity was compared with that of ciprofloxacin and five other antibiotics. sparfloxacin was the most active drug tested against methicillin-sensitive and methicillin-resistant staphylococcus aureus (mrsa) and coagulase-negative staphylococci (mic90, 0.125-0.25 mg/l). sparfloxacin was also the most active drug tested against ente ... | 1991 | 1665123 |
| multiresistant corynebacteria in bacteriuria: a comparative study of the role of corynebacterium group d2 and corynebacterium jeikeium. | during an 11-month prospective study, urine cultures were performed on 5685 samples obtained in three hospital units. the use of a selective medium improved the recovery of antibiotic-multiresistant corynebacteria (amc): 703 isolates (12.4%) compared with 88 isolates (1.6%) on sheep blood agar. corynebacterium group d2 (cgd2) was isolated in 80.5% of urines yielding greater than or equal to 10(5) amc ml-1 whereas corynebacterium jeikeium represented 80.2% of isolates with less than 10(5) amc ml- ... | 1991 | 1672322 |
| an investigation of nosocomial infection with corynebacterium jeikeium in surgical patients using a ribosomal rna gene probe. | twelve strains of multi-resistant corynebacterium jeikeium isolated during a one year period in a surgical unit in innsbruck were analyzed with regard to their plasmid content, antibiotic susceptibility, and the use of ribosomal ribonucleic acid (rrna) to probe restriction fragment length polymorphism (rflp). plasmids were detected in five of the strains. southern blotting of genomic dna digested with hindiii or pvuii and hybridized with a biotin-labelled cdna probe derived from total rrna revea ... | 1990 | 1699761 |
| hsp 90, yeasts and corynebacterium jeikeium. | recovery from disseminated candidosis is associated with seroconversion to a 47 kda breakdown product of the heat shock protein (hsp) 90 of candida albicans. cloning, sequencing and epitope mapping has allowed the delineation of the immunodominant epitopes lkvirknivkkmie and stdepagesa. monoclonal and polyclonal antibodies specific to these epitopes are used to show that all strains of c. albicans tested produce hsp 90 in both the yeast and mycelial phases. homologous proteins are demonstrated i ... | 1991 | 1718769 |
| comparative in vitro activity of the new glycopeptide sk&f 104662 against problematic gram-positive bacteria. | the in vitro activity of the new glycopeptide antibiotic sk&f 104662 against problematic gram-positive microorganisms was determined using the agar dilution technique. for comparison, ampicillin, oxacillin, vancomycin, erythromycin and gentamicin were tested. sk&f 104662 was found to have high activity against staphylococcus aureus, coagulase-negative staphylococci (both methicillin sensitive and resistant strains), enterococcus faecalis, enterococcus faecium, listeria monocytogenes, corynebacte ... | 1991 | 1810738 |
| in vitro evaluation of gr69153, a novel catechol-substituted cephalosporin. | gr69153 is a c-7 catechol cephalosporin with a broad spectrum of activity against members of the family enterobacteriaceae (mics for 50% of strains tested [mic50s], 0.008 to 0.5 micrograms/ml), staphylococcus aureus (mic50, 4 micrograms/ml), pseudomonas aeruginosa (mic50, 0.25 micrograms/ml), haemophilus influenzae (mic50, 0.03 micrograms/ml), neisseria gonorrhoeae (mic50, 0.03 micrograms/ml), and acinetobacter spp. (mic50, 2 micrograms/ml). potent gr69153 activity was also demonstrated against ... | 1991 | 1854174 |
| corynebacterium minutissimum infection. | two cases of infection due to corynebacterium minutissimum are described. on the basis of biochemical tests the organisms were thought at first to be corynebacterium jeikeium. methods of distinguishing between these species and the role of c. minutissimum in the pathogenesis of erythrasma and other skin infections are discussed. | 1991 | 1885917 |
| corynebacterium jeikeium bacteremia at a tertiary care center. | during a six-year period 23 patients with isolation of corynebacterium jeikeium (formerly known as corynebacterium group jk) from one or more blood cultures at a university hospital were identified. cases occurred sporadically without time- or ward-related clustering. review of the cases showed that most infections were nosocomial, that most of the patients had underlying malignant disease, had a chronic intravascular catheter implanted, had been pretreated with antibiotics, and were neutropenic ... | 1991 | 1917029 |
| [endocarditis caused by corynebacterium jeikeium]. | | 1991 | 1932248 |
| vancomycin. | vancomycin is a glycopeptide antibiotic that is active against staphylococci, streptococci, and other gram-positive bacteria. it is the drug of choice for the treatment of infections due to methicillin-resistant staphylococci, corynebacterium jeikeium, and multiply resistant strains of streptococcus pneumoniae. vancomycin is an alternative treatment for serious staphylococcal and streptococcal infections, including endocarditis, when allergy precludes the use of penicillins and cephalosporins. v ... | 1991 | 1943250 |
| mass spectrometry as a tool for identifying group d2 corynebacteria by their fatty acid profiles. | corynebacterium group d2 (cgd2) are lipophilic antibiotic-multiresistant bacteria involved in some infections of immunocompromised patients. the fatty acid composition and structure of different strains was established by several mass spectrometric methods, particularly negative ion tandem mass spectrometry coupled with capillary gas chromatography. non-hydroxylated fatty acid profiles of three strains of cgd2 (atcc 43042, atcc 43043, atcc 43044) were almost identical and revealed the presence o ... | 1991 | 1955869 |
| antigenic cross-reactivity among isolates of group jk corynebacteria. | using rocket and rocket-line immunoelectrophoresis and immunoblotting it was demonstrated that a group of antibiotic-resistant bacteria, including several authenticated corynebacterium jeikeium strains, shared many cross-reacting antigens. only weak cross-reactivity was demonstrated with representatives of three other skin corynebacteria, c. bovis, c. hofmanii and c. minutissimum or with non-coryneforms. differences within c. jeikeium are sufficient to permit the use of immunoblotting as an epid ... | 1990 | 1976676 |
| bacteremia due to corynebacterium jeikeium in a patient with aids. | | 1991 | 2041970 |
| palpable purpura associated with corynebacterium jeikeium endocarditis. | | 1991 | 2064416 |
| in vitro susceptibility of corynebacterium group d2 and corynebacterium jeikeium to twelve antibiotics. | the in vitro susceptibility of 83 corynebacterium group d2 strains and 44 corynebacterium jeikeium strains to 12 antimicrobial agents was determined by an agar dilution technique using mueller-hinton agar supplemented with tween 80 (0.025%). all strains of corynebacterium group d2 were highly sensitive to fusidic acid, pristinamycin, teicoplanin and vancomycin (geometric mean mics 0.047, 0.048, 0.338 and 0.396 mg/l respectively). most of the strains were resistant to other antibiotics tested (ci ... | 1990 | 2073900 |
| antimicrobial activity and beta-lactamase stability of bmy-28232, parent compound of an oral cephalosporin. | bmy-28232, an aminothiazolyl imino methoxy cephalosporin which is available as an orally absorbed acetoxyethyl ester, inhibited strains of methicillin-susceptible staphylococcus aureus, hemolytic streptococci, streptococcus pneumoniae, escherichia coli, klebsiella species, and many strains of proteus and providencia stuartii at concentrations less than 1 microgram/ml, including isolates resistant to cephalexin and cefaclor. it had activity similar to that of cefixime, but was more active against ... | 1990 | 2086221 |
| [corynebacterium jeikeium]. | | 1990 | 2098141 |
| [corynebacterium jeikeium septicemia]. | an adult male with non-hodgkin lymphoma, who had been admitted to the hospital for more than one month and had received previous antibiotic therapy, developed corynebacterium jeikeium septicemia. the organism was isolated in four blood cultures and it was multirresistant, being only sensitive to vancomycin, ciprofloxacin, norfloxacin and rifampin. the patient improved clinically and was bacteriologically cured with intravenous vancomycin therapy. | 1990 | 2098146 |
| comparative evaluation of nonradiometric bactec and improved oxoid signal blood culture systems in a clinical laboratory. | the bactec nr660 blood culture system, which uses infrared spectroscopy to detect carbon dioxide generated by bacterial growth, was compared with the new medium formulation of the oxoid signal system. two trials were conducted: a comparative study of 88 organisms in simulated blood cultures and a clinical trial of 3,321 paired patient blood culture samples. both trials showed that overall the bactec system performed better in the recovery of organisms. the oxoid system was unable to detect by si ... | 1990 | 2116450 |
| in vitro activity of fleroxacin against aerobic gram-positive bacteria including corynebacterium jeikeium. | fleroxacin (ro 23-6240, am-833), a new fluoro-4-quinolone, was tested in vitro against 273 gram-positive clinical isolates. norfloxacin, a quinolone mostly used in urinary tract infections, was included as a standard. overall, in vitro activities of fleroxacin and norfloxacin were superposable, but interestingly, fleroxacin was two- to fourfold more active against staphylococcus aureus, and 1 mg/l of fleroxacin inhibited all 5 multiply resistant corynebacterium jeikeium tested. while both quinol ... | 1990 | 2127242 |
| in vitro activity of sparfloxacin (ci-978; at-4140) against clinical isolates from cancer patients. | the in vitro activity of sparfloxacin, a new quinolone, was compared with those of ciprofloxacin and fleroxacin against gram-positive and gram-negative bacteria, greater than 90% of which were isolated from blood culture specimens of cancer patients. sparfloxacin was extremely active against acinetobacter species, aeromonas hydrophila, citrobacter diversus, enterobacter species, escherichia coli, klebsiella species, proteus vulgaris, and serratia marcescens (inhibiting greater than 90% of these ... | 1990 | 2127348 |
| comparative in vitro activity of the new erythromycin derivative dirithromycin against gram-positive bacteria isolated from cancer patients. | the in vitro activity of dirithromycin (ly-237216), a new macrolide erythromycin derivative, was compared to that of four other agents (clarithromycin, erythromycin, roxithromycin, clindamycin) against 334 gram-positive isolates obtained from cancer patients. dirithromycin was similar in potency and antimicrobial spectrum to the other agents tested. it was very active against beta-haemolytic streptococci and streptococcus pneumoniae, and moderately active against penicillin and methicillin susce ... | 1990 | 2137413 |
| in vitro activity of ly264826, a new glycopeptide antibiotic, against gram-positive bacteria isolated from patients with cancer. | the in vitro activity of ly264826, a novel glycopeptide antibiotic produced by amycolatopsis orientalis, was compared with those of vancomycin, teicoplanin, and oxacillin against 311 gram-positive clinical isolates from patients with cancer, ly264826 had lower mics for 90% of isolates (mic90) than vancomycin for all species tested. it was active against oxacillin-resistant isolates including staphylococcus aureus (mic90, 0.5 micrograms/ml), staphylococcus haemolyticus (mic90, 2.0 micrograms/ml), ... | 1990 | 2149921 |
| in vitro activity of pd127,391, a new quinolone against bacterial isolates from cancer patients. | the in vitro activity of pd127,391, a new 4-quinolone, was compared to that of ciprofloxacin against common clinical bacterial isolates from patients with cancer. pd127,391 was found to have a broad antimicrobial spectrum with excellent activity against gram-positive isolates (including multidrug-resistant organism such as corynebacterium jeikeium, enterococcus faecalis, enterococcus faecium, methicillin-resistant staphylococcus aureus and coagulase-negative staphylococcus spp.). it was also ext ... | 1990 | 2209169 |
| characterization of the antibody response in corynebacterium jeikeium septicaemias. | corynebacterium jeikeium causes septicaemia in neutropenic patients usually after colonizing intravenous lines. this paper reports the results of immunoblotting sera from 14 patients with a c. jeikeium septicaemia. recovery from the septicaemia was associated with production of both igm and igg against antigenic bands of 50, 52 and 110 kda. antibody against the 110 kda band was present in controls but the antibody against the 50 and 52 kda was specific to those patients who had on-going or previ ... | 1990 | 2209731 |
| catheter-related right-sided endocarditis in bone marrow transplant recipients. | bone marrow transplant recipients are at increased risk of severe central venous catheter-related septicemias that may be complicated by endocardial infection. in view of this, we prospectively evaluated 141 consecutive patients receiving allogeneic or autologous bone marrow infusion. seven (5%) of 141 patients developed eight episodes of a clinical syndrome compatible with catheter-related right-sided infective endocarditis; this diagnosis was confirmed at autopsy in two patients who died. stap ... | 1990 | 2330480 |
| in-vitro activity of the streptogramin group of antimicrobials against corynebacterium jeikeium and d2 coryneform bacteria. | | 1989 | 2499566 |
| antimicrobial activity of ro 23-9424, a novel ester-linked codrug of fleroxacin and desacetylcefotaxime. | ro 23-9424 is a novel ester-linked codrug of fleroxacin (ro 23-6240; am-833) and the cefotaxime metabolite desacetylcefotaxime. its potency was determined against over 1,000 organisms and found to be intermediate between those of the two components. more than 99% of members of the family enterobacteriaceae were inhibited by greater than or equal micrograms of ro 23-9424 per ml; its mic for 50% of strains tested ranged from greater than or equal to 0.06 to 1 micrograms/ml. staphylococci, streptoc ... | 1989 | 2504106 |
| in vitro evaluation of ramoplanin (a16686 or mdl62198). a new depsipeptide complex for potential topical use. | ramoplanin, a new depsipeptide complex, was found to be 4- to 8-fold more active than vancomycin against all gram-positive species (500 strains). similarly, ramoplanin was both more active and had an additional spectrum compared to mupirocin (formerly pseudomonic acid) against bacillus spp., corynebacterium jeikeium, enterococci and listeria monocytogenes. mupirocin-resistant staphylococcus spp. strains (less than 1%) were identified in these organisms collected from over 40 medical centers in t ... | 1989 | 2507218 |
| [group jk (corynebacterium jeikeium sp. nov.) isolated from japanese skin flora]. | in many parts of the world, the emergence of multiple antibiotic resistant group jk has been recognized as an important cause of nosocomial infection in immunosuppressed and neutropenic patients. group jk infections have not been reported from japan. we studied 20 japanese who had recently come to the united states and recovered group jk from 7 of 20. these results suggest that group jk may be prevalent in japanese. previous failure to identify these organisms may reflect their poor growth on ag ... | 1989 | 2607672 |
| corynebacterium jeikeium (group jk diphtheroids) endocarditis. a report of five cases. | corynebacterium jeikeium is the name recently given to a group of coryneform rods, formerly known as the jk group, and associated with a wide range of serious infections. we describe five patients with c. jeikeium endocarditis observed in two belgian hospitals over a period of 5 years. in three cases, the infection occurred on prosthetic heart valves between 1.5 and 5 months after surgery. the two other patients, with known mitral insufficiency, presented with endocarditis on native valves. in f ... | 1989 | 2791490 |
| opsonophagocytosis of bacteria studied by chemiluminescence in microtitre plates. | a protocol for polymorphonuclear leukocyte chemiluminescence (pmn cl) assays of opsonophagocytosis was developed for a microtitre-plate luminometer. the complete procedure was performed in a single microtitre plate and was simpler and more efficient than previous protocols. the kinetics of the pmn cl response were best when microtitre plates were incubated on a shaking incubator between readings. the new protocol was used in a study of the pathogenicity of corynebacterium jeikeium, an organism f ... | 1989 | 2801217 |
| activity of meropenem, against gram-positive bacteria. | a new carbapenem antibiotic, meropenem, was shown to be active against a large number of gram-positive bacteria. the drug inhibited penicillinase-positive and -negative, methicillin-susceptible staphylococci equally well. among the comparative antimicrobials examined, only n-formimidoyl-thienamycin (imipenem) was two to four times more active than meropenem. compared with vancomycin or methicillin, meropenem was 10-20 times more active. strains of 11 species of streptococci were highly susceptib ... | 1989 | 2808202 |
| infections caused by antibiotic-resistant corynebacterium group d2. | a coryneform bacteria known as corynebacterium group d2 pending definitive taxonomic classification, has emerged as a human pathogen. although first described 16 years ago, the organism has only recently been implicated in clinical infections. it differs from all previously recognized species of corynebacterium, and in common with corynebacterium jeikeium exhibits a broad spectrum of antimicrobial resistance, being sensitive to only vancomycin, teicoplanin and some quinolones. the microorganisms ... | 1988 | 3137032 |
| identification of corynebacterium jeikeium and corynebacterium cdc group d2 with the api 20 strep system. | a total of 170 strains of corynebacterium jeikeium and 23 strains of corynebacterium group d2 were examined in three british laboratories using the api 20 strep identification system and three supplementary tests (catalase production, urease production and nitrate reduction). the isolates were collected from clinical specimens in various laboratories over a three-year period. the two species produced consistent reactions in these tests after 24 h. two tests were highly discriminatory, with posit ... | 1988 | 3143582 |
| [corynebacterium jeikeium. multiresistant diphtheroids as a cause of nosocomial infections]. | | 1988 | 3206432 |
| antimicrobial activity of mdl 19,592: an oral cephalosporin. | mdl 19,592, a semisynthetic oral cephalosporin, has an antimicrobial spectrum principally directed against gram-positive cocci (mic50, 0.25-4 micrograms/ml), branhamella catarrhalis (mic50, 1-2 micrograms/ml), and pathogenic neisseria spp. such as meningococci (mic50, 4 micrograms/ml). enterobacteriaceae, enterococci, pseudomonas spp., corynebacterium jeikeium, and acinetobacter calcoaceticus strains had mdl 19,592 mic50 of greater than or equal to 32 micrograms/ml. although mdl 19,592 generally ... | 1988 | 3246143 |
| corynebacterium jeikeium (group jk) resistance to ciprofloxacin emerging during therapy. | | 1987 | 3440776 |
| epitope mapping human heat shock protein 90 with sera from infected patients. | epitope mapping with sera from a range of infected patients showed that antibodies are commonly produced which cross-react with a number of epitopes on human heat shock protein 90 (hsp 90). such autoreactive antibodies were particularly frequent in patients suffering from systemic candidiasis (9 patients), invasive aspergillosis (6 patients), abpa (2 patients), a patient with aspergilloma and one with malaria. the patient with malaria recognized similar epitopes to those with invasive aspergillo ... | 1994 | 7512400 |
| osteomyelitis caused by corynebacterium jeikeium. | a case study has been presented where c. jeikeium was isolated as the causative bacterium of an osteomyelitis of the fifth metatarsal. partial amputation, local wound care, frequent and aggressive debridement, and appropriate antibiotics were all used with apparent success. the lack of complete patient follow-up prohibits the authors from declaring the infection cured; however, all signs of infection were absent immediately prior to discharge. the authors believe this to be the first reported ca ... | 1995 | 7602508 |
| comparison of e-test with broth microdilution and disk diffusion for susceptibility testing of coryneform bacteria. | the susceptibilities of 135 coryneform bacteria isolated from clinical samples to ampicillin (amp), cephalothin (cr), cefoxitin (fox), cefotaxime (ctx), erythromycin (e), ciprofloxacin (cip), tetracycline (te), amikacin (ak), vancomycin (va), and rifampin (r) were determined by disk diffusion, broth microdilution, and the e-test. the following species (number of isolates in parentheses) were included: corynebacterium urealyticum (30), corynebacterium minutissimum (20), coryneform cdc group anf-1 ... | 1995 | 7615748 |
| gadolinium-based mr contrast media: potential for growth of microbial contaminants when single vials are used for multiple patients. | to assess potential risk if single-dose vials of gadolinium-based contrast media are used for multiple patients. the use of multidose vials can pose a significant risk if contaminants are accidentally introduced into the vials and proliferate. therefore, we tested the ability of gadolinium-based contrast to support the growth of a variety of microbial pathogens. | 1995 | 7645493 |
| antimicrobial susceptibilities of corynebacterium species and other non-spore-forming gram-positive bacilli to 18 antimicrobial agents. | the susceptibilities of 265 strains of corynebacterium species and other non-spore-forming gram-positive bacilli to 18 antimicrobial agents were tested. most strains were susceptible to vancomycin, doxycycline, and fusidic acid. corynebacterium jeikeium and corynebacterium urealyticum were the most resistant organisms tested. resistance to beta-lactams, clindamycin, erythromycin, azythromycin, ciprofloxacin and gentamicin was common among strains of corynebacterium xerosis and corynebacterium mi ... | 1995 | 7695308 |
| opportunistic nosocomial multiply resistant bacterial infections--their treatment and prevention. | one of the most difficult problems confronting the clinician who deals with nosocomial infections is that of microbial resistance. the predominant nosocomial infections (urinary tract infections, pneumonia, septicaemia, surgical wound infections) involve increasing numbers of gram-positive bacteria, staphylococcus epidermidis, corynebacterium jeikeium or resistant enterococci as well as new multiresistant gram-negative bacilli such as xanthomonas maltophilia, acinetobacter baumannii and alcalige ... | 1993 | 7755661 |
| problems in minimum inhibitory concentration determinations in coryneform organisms. comparison of an agar dilution and the etest. | the antimicrobial susceptibility of 159 coryneform organisms was determined by an agar dilution and etest methods. overall, the correlation between minimum inhibitory concentrations obtained by both techniques was good (> or = 0.09) for most antibiotics and organisms although the essential agreement ranged from 59% to 88.3%. most organisms were equally categorized (sensitive, intermediate, or resistant) by both methods with only 0.2%, 0.4%, and 3.5% of very major, major or minor discrepancies, r ... | 1994 | 7820998 |
| cefquinome (hr 111v). in vitro evaluation of a broad-spectrum cephalosporin indicated for infections in animals. | cefquinome (formerly hr 111v), an aminothiazolyl cephalosporin, was compared with cefepime, cefpirome, cefotaxime, and ceftazidime against 681 clinical cultures and a challenge set of bacteria with well-characterized resistance mechanisms. cefquinome minimum inhibitory concentrations (mic90) for the enterobacteriaceae ranged from < or = 0.12-2 micrograms/ml with the highest mic (4 micrograms/ml) obtained among citrobacter freundii, enterobacter cloacae, and providencia stuartii strains. a total ... | 1994 | 7867299 |
| [a case of corynebacterium jeikeium septicemia]. | we report a case of corynebacterium jeikeium septicemia associated with malignant lymphoma. the patient is a 58-year-old male who was diagnosed as malignant lymphoma on august 1992. may 15, 1993, he was admitted to our hospital because of oliguria, abdominal flatulence and vomiting which developed a few days before admission. anticancer regimen were started. in the middle of july, white blood cell (wbc) count dropped to 100/mm3 and body temperature rose to 39 degrees c. he was been treated with ... | 1994 | 7876676 |
| [nosocomial infections: new agents, incidence, prevention]. | nosocomial infection is one of the major health problems confronting clinicians in intensive care units. incidence has been estimated to vary from 5 to 10%, leading to death in one of every 5000 persons hospitalized. this situation is not however static since hospital epidemics and nosocomial infections evolve as a consequence of advances in antibiotic drug therapy and surgical and intensive care techniques. microbial investigations themselves are of major importance as the collection of epidemi ... | 1995 | 7899352 |
| improved enrichment broth for cultivation of fastidious organisms. | an enrichment broth developed in our laboratory, fastidious broth (fb), was compared with two commercially available broth media, supplemented thioglycolate broth and enriched eugonic broth. fb supported the growth of a number of organisms that were not cultivatable in either of the other two media, including corynebacterium jeikeium, haemophilus influenzae, neisseria gonorrhoeae, and streptococcus pneumoniae. in addition, for several organisms that were able to grow in all three broths, includi ... | 1994 | 7929784 |
| corynebacterium jeikeium osteomyelitis following total hip joint replacement. | | 1994 | 7963628 |
| genomic diversity among corynebacterium jeikeium strains and comparison with biochemical characteristics and antimicrobial susceptibilities. | levels of dna relatedness were determined by performing dna-dna hybridization experiments (s1 nuclease procedure) with 13 human isolates exhibiting various antimicrobial susceptibility patterns which had been identified as corynebacterium jeikeium by classical tests and the api coryne system and with reference strains of c. jeikeium and related taxa. twelve of 13 isolates which formed three genomic groups showed between 22 and 75% relatedness with the type strain of c. jeikeium. one of these gen ... | 1994 | 7989533 |
| treatment of shunt-related cerebral ventriculitis due to corynebacterium jeikeium with vancomycin administered intraventricularly. case report. | a 52-year-old female with subarachnoid haemorrhage and hydrocephalus was treated with external and later internal drainage. she developed ventriculoperitoneal shunt-related ventriculitis caused by corynebacterium jeikeium. the infection was unsuccessfully treated with intravenous vancomycin. it was controlled only after shunt removal and administration of intraventricular vancomycin as well as systemic vancomycin, rifampicin and fusidic acid. a review of the literature confirmed our experience t ... | 1994 | 8011309 |
| comparative in vitro activities of new quinolones against coryneform bacteria. | the in vitro activities of eight quinolones against 115 coryneform bacteria (20 corynebacterium jeikeium, 15 corynebacterium minutissimum, 15 corynebacterium striatum, 25 corynebacterium urealyticum, 10 corynebacterium xerosis, 10 corynebacterium group anf-1, 10 corynebacterium group 12, and 10 listeria monocytogenes) were determined. the mics of ciprofloxacin, ofloxacin, and sparfloxacin for 90% of c. jeikeium, c. urealyticum, and c. xerosis isolates tested were > 16 micrograms/ml. those of bay ... | 1994 | 8092851 |
| corynebacterium jeikeium infection in trinidad. | | 1993 | 8104992 |
| predisposition to corynebacterium jeikeium infection in acute lymphoblastic leukemia: a report of two cases in trinidad. | two hospitalized patients (a 4 and 6 year old male and female, respectively) with acute lymphoblastic leukaemia (all), had each at different periods sustained burns with necrosis from extravasation of chemotherapeutic products. pure cultures from their wound exudates and blood repeatedly revealed corynebacterium jeikeium, an organism recognized and identified in the last decade as an opportunistic cause of life-threatening nosocomial infections particularly in patients on long-term multiple anti ... | 1994 | 8127260 |
| [bacteremia caused by campylobacter jeikeium in 2 aids patients without neutropenia]. | bacteremia by corynebacterium jeikeium is generally described in patients with a bone marrow transplantation and/or neutropenia. in 1991, the first case of bacteremia by c. jeikeium was described in a patient with aids and neutropenia. the aim of this study was to describe 2 cases of bacteremia by c. jeikeium in patients with aids without neutropenia. to the authors' knowledge, this presentation has not been described previously. | 1994 | 8155752 |
| continuous ambulatory peritoneal dialysis: evaluation of three new culture methods. | out of 900 dialysates analysed over 15 months at the rennes regional hospital, 116 cloudy specimens with a leucocyte count of more than 100/mm3 were studied. three methods of laboratory diagnosis based on physical or chemical disruption of leucocytes were evaluated: saponin incorporated in the agar medium, sonication, and the isolator lysis centrifugation system. sensitivity was improved (52%) for the three methods combined compared with the standard method (37%). the isolator system (51%, p < 0 ... | 1993 | 8166385 |
| liver abscess due to corynebacterium jeikeium in a patient with aids. | | 1993 | 8218703 |
| in vitro activities of bay y3118, ciprofloxacin, ofloxacin, and fleroxacin against gram-positive and gram-negative pathogens from respiratory tract and soft tissue infections. | bay y3118 was highly active against moraxella catarrhalis, haemophilus influenzae, legionella pneumophila, escherichia coli, klebsiella pneumoniae, staphylococcus aureus (except quinolone-resistant, methicillin-resistant s. aureus), staphylococcus epidermidis, streptococcus pyogenes, streptococcus agalactiae, and streptococcus pneumoniae (mic for 90% of strains tested [mic90], 0.063 micrograms/ml). for enterococcus faecalis and corynebacterium jeikeium, mic90s were 4 and 2 micrograms/ml, respect ... | 1993 | 8239624 |
| rapid method for presumptive identification of corynebacterium jeikeium. | corynebacterium jeikeium causes systemic infections, particularly in immunocompromised hosts. a minitube assay has been developed for the presumptive identification of c. jeikeium. with our rapid sucrose-urea test and conventional biochemical tests, sixty isolates of gram-positive, catalase-positive bacilli were identified in our laboratory. results indicated that our assay has a sensitivity of 100% and a specificity of 90%. | 1993 | 8308128 |
| corynebacterium striatum: a diphtheroid with pathogenic potential. | although nondiphtherial corynebacteria are ubiquitous in nature and commonly colonize the skin and mucous membranes of humans, they rarely account for clinical infection. corynebacterium striatum has rarely been reported to be a pathogen, causing pleuropulmonary infections and bacteremia in only immunocompromised or anatomically altered patients. we noted c. striatum to be the infecting pathogen or copathogen in six patients. to our knowledge, this report describes the first cases of c. striatum ... | 1993 | 8353242 |
| identification of clinical isolates of nondiphtherial corynebacterium species and their antibiotic susceptibility patterns. | starting in 1982, our laboratory has performed species identification of coryneform bacteria isolated from blood cultures, intravenous (i.v.) catheter tips and sites, urines with high colony counts, and other potentially significant cultures, using predefined criteria. of 283 isolates identified, corynebacterium jeikeium was the most common (47%), followed by cdc group g2 (12%) and c. minutissimum (8%). blood cultures and i.v. catheter-related sources were the most frequent sources (58% of total ... | 1993 | 8359002 |
| adherence of corynebacterium urealyticum (cdc group d2) and corynebacterium jeikeium to intravascular and urinary catheters. | the ability of corynebacterium urealyticum, corynebacterium jeikeium and other control strains to adhere to two intravascular catheters (polyvinyl chloride and teflon) and one urinary catheter (teflon-coated rubber) was studied. results demonstrated that the corynebacterium species adhered to all catheter materials in greater numbers than a control strain of micrococcus luteus (p < 0.001). there was not a clear difference in the ability of the strains of corynebacterium jeikeium and corynebacter ... | 1993 | 8359166 |
| numerical analysis of fatty and mycolic acid profiles of corynebacterium urealyticum and other related corynebacteria. | the fatty and mycolic acid profiles of 52 strains of clinical origin belonging to corynebacterium urealyticum were subjected to numerical analysis along with those of representative members of corynebacterium ammoniagenes, corynebacterium bovis, corynebacterium glutamicum, corynebacterium jèikeium, corynebacterium minutissimum, corynebacterium pseudodiphtheriticum, corynebacterium pseudotuberculosis, corynebacterium xerosis, corynebacterium renale, corynebacterium cystitidis, "corynebacterium ul ... | 1993 | 8397966 |
| ventricular csf shunt infections associated with corynebacterium jeikeium: report of three cases and review. | ventricular csf shunt infections due to corynebacterium jeikeium are rare. such infections may become manifest weeks to months after surgery. they are difficult to eradicate and often recur. we report three cases of c. jeikeium ventricular csf shunt infections, all of which occurred in patients who received long-term prophylactic therapy with antibiotics and had protracted hospitalizations. two patients had multiple recurrences, and all patients required shunt revision. additional therapy with i ... | 1993 | 8448291 |
| computerized surveillance in clinical microbiology with time series analysis. | an automatic surveillance system to detect changes in the incidences of microorganisms diagnosed in the department of clinical microbiology has been developed. the program is incorporated into the laboratory computer system and gives a weekly list of microorganisms whose isolation rates compared with those of a previous period exceed a chosen limit. the system uses time series analysis with moving weighted averages, and the detection limit is based on the distribution of the residuals. output fr ... | 1993 | 8463397 |
| in-vitro activity of dirithromycin in comparison with other new and established macrolides. | improvements with regard to the in-vitro activity of new macrolides are marginal and apply mainly to haemophilus spp., moraxella catarrhalis and neisseria gonorrhoeae (e.g. azithromycin is two to eight times more active than erythromycin) and to non-enterococcal streptococci (e.g. clarithromycin is two to four times more active than erythromycin). the increase in activity against staphylococci is even less striking, being restricted to a few species and limited to clarithromycin (twice as active ... | 1993 | 8478311 |
| phosphorylcholine-containing antigens in bacteria from the mouth and respiratory tract. | phosphorylcholine (pc)-containing antigens were sought in 269 bacterial isolates from the mouth and respiratory tract by an enzyme immunoassay method. only 41 (15%) isolates were pc-positive and of these 29 (70%) were strains of haemophilus influenzae. other species that produced positive results included two of five isolates of gemella haemolysans, two of five isolates of micrococcus spp., and a single strain each of bacillus sp., corynebacterium jeikeium, lactococcus sp. and h. parainfluenzae. ... | 1996 | 8544209 |
| a papular eruption secondary to infection with corynebacterium jeikeium, with histopathological features mimicking botryomycosis. | corynebacterium jeikeium has been increasingly recognized as a pathogen, particularly in immunocompromised patients and in those with a prosthetic heart valve. although cutaneous manifestations of c. jeikeium infection have been described, we have only found two case reports that give an histological description of the lesions. we present three patients with haematological malignancies who developed infection with c. jeikeium and a papular eruption. skin biopsy disclosed similar histological fea ... | 1995 | 8555040 |
| corynebacterium cdc group jk (corynebacterium jeikeium) sepsis in haematological patients: a report of three cases and a systematic literature review. | we describe 3 patients with corynebacterium jeikeium sepsis in neutropenic phase during treatment for acute myeloid leukaemia. fever was the first symptom. all had a central venous catheter which was removed. two patients developed subcutaneous nodules containing pus when the neutrophil count recovered; 1 had intracutaneous and pulmonary lesions. they were treated with vancomycin and recovered when the neutrophil count started to rise. a review of 80 neutropenic patients with c. jeikeium sepsis ... | 1995 | 8685637 |
| total knee arthroplasty complicated by corynebacterium jeikeium infection. | corynebacterium jeikeium is a slow-growing multiresistant micro-organism. it causes serious opportunistic infections in patients with long hospital stays who receive broad-spectrum antibiotics. it can be isolated from blood and other sites in neutropenic, immunosuppressed bone marrow recipients and in patients with indwelling catheters. cases of infection related to bone and joint replacements are rare. this case is the first where corynebacterium jeikeium has been isolated from an infected knee ... | 1995 | 8685647 |
| a risk-benefit assessment of teicoplanin in the treatment of infections. | teicoplanin is a glycopeptide antibiotic whose activity is selectively oriented against gram-positive aerobic and anaerobic bacteria, including staphylococcus aureus, coagulase-negative staphylococci, clostridium difficile, peptostreptococcus spp. and corynebacterium jeikeium; such activity is affected by neither methicillin resistance nor beta-lactamase production. teicoplanin is not significantly absorbed from the gastrointestinal tract; consequently, it has to be administered intravenously (e ... | 1995 | 8785019 |
| comparison of antimicrobial susceptibilities of corynebacterium species by broth microdilution and disk diffusion methods. | corynebacterium species are increasingly being implicated in foreign-body infections and in immunocompromised-host infections. however, there are no specific recommendations on the method or the criteria to use in order to determine the in vitro activities of the antibiotics commonly used to treat corynebacterium infections. the first aim of our study was to compare the susceptibilities of various species of corynebacterium to vancomycin, erythromycin, and penicillin by using a broth microdiluti ... | 1996 | 8849254 |
| in vitro antimicrobial activities and spectra of u-100592 and u-100766, two novel fluorinated oxazolidinones. | two new fluorinated oxazolidinones, u-100592 and u-100766, were evaluated against more than 659 gram-positive and -negative organisms and compared with glycopeptides, erythromycin, clindamycin, clinafloxacin, and chloramphenicol. u-100592 and u-100766 were usually equally potent, but the mics at which 90% of the isolates are inhibited (mic90s) of u-100592 for some staphylococci and enterococci were slightly lower than those of u-100766 (1 versus 2 micrograms/ml). the mic90 of u-100592 and u-1007 ... | 1996 | 8851600 |
| species identities and antimicrobial susceptibilities of corynebacteria isolated from various clinical sources. | over a 14-month period, 415 clinical isolates of coryneform gram-positive rods were recovered from various sources and identified to the species level according to recent identification schemes. corynebacterium urealyticum, corynebacterium striatum, corynebacterium amycolatum, and corynebacterium jeikeium predominated, accounting for 63% of all isolates. corynebacterium accolens, corynebacterium striatum, corynebacterium argentoratense, corynebacterium propinquum and corynebacterium pseudodiphth ... | 1996 | 8894575 |
| arcanum. corynebacterium jeikeium. | | 1996 | 9044660 |
| microbial growth inside saline-filled breast implants. | in vitro and in vivo experiments were conducted to determine whether intraluminal saline in breast implants can support the growth of common wound-infecting microorganisms over a prolonged period of time. the bacteria tested were staphylococcus aureus, staphylococcus epidermidis, escherichia coli, corynebacterium jeikeium, enterobacter cloacae, klebsiella pneumoniae, and pseudomonas aeruginosa. three fungal species also were tested: aspergillus fumigatus, paecilomyces variotii, and candida albic ... | 1997 | 9207676 |
| in vitro antimicrobial activity and mic quality control guidelines of rpr 106972 (rpr 112808/rpr106950): a novel orally administered streptogramin combination. the quality control study group. | rpr 106972 is a novel oral streptogramin combination with reported therapeutic potency against gram-positive and certain respiratory tract pathogens. mics for rpr 106972, quinupristin/dalfopristin, and seven comparison drugs were determined by the reference methods against 337 strains selected to define spectrum and potency. rpr 106972 demonstrated antimicrobial activity against oxacillin-susceptible and -resistant staphylococcus aureus (mic ranges of 0.12 to 2 micrograms/ml and 0.5 to 2 microgr ... | 1997 | 9294704 |
| corynebacterium jeikeium osteomyelitis successfully treated with teicoplanin. | | 1997 | 9459422 |
| prospective study of catalase-positive coryneform organisms in clinical specimens: identification, clinical relevance, and antibiotic susceptibility. | during a 6-month period, all clinical isolates of catalase-positive coryneform organisms, which were isolated during the routine processing of clinical specimens, were characterized in the laboratory of the 1800-bed university hospital of leuven. the distribution of the species in the corynebacteria was: corynebacterium amycolatum 70 (53%), corynebacterium jeikeium 16 (12%), corynebacterium striatum 11 (8%), corynebacterium afermentans 10 (7%), corynebacterium minutissimum 9 (6%), cdc coryneform ... | 1998 | 9488824 |
| diversity of coryneforms found in infections following prosthetic joint insertion and open fractures. | in a 5-year period, 73 coryneform isolates from prosthetic joint and open fracture infections in 60 patients treated in a hospital specialized in orthopedic surgery were speciated. the most frequent species were corynebacterium amycolatum, corynebacterium striatum, corynebacterium diphtheriae biotype mitis, and corynebacterium jeikeium. at least 14 isolates were deemed clinically significant as sole agents of infection. | 1998 | 9505178 |
| minimal inhibitory concentrations and minimal bactericidal concentrations of quinupristin/dalfopristin against clinical isolates of corynebacterium jeikeium and listeria monocytogenes. | thirty clinical isolates of listeria monocytogenes and 30 clinical isolates of corynebacterium jeikeium were tested against quinupristin/dalfopristin by the nccls broth macrodilution technique for determination of mics. mbc testing was also performed on the 60 isolates. quinupristin/dalfopristin mic90 values against l. monocytogenes and c. jeikeium were 1.6 mg/l and 0.2 mg/l, respectively. quinupristin/dalfopristin was bacteriostatic against these organisms. | 1997 | 9511066 |
| in vitro susceptibilities of aerobic and facultative non-spore-forming gram-positive bacilli to hmr 3647 (ru 66647) and 14 other antimicrobials. | the comparative in vitro activity of the ketolide hmr 3647 (ru 66647) and those of structurally related macrolide-lincosamide-streptogramin compounds (erythromycin, roxithromycin, azithromycin, clarithromycin, josamycin, lincomycin, pristinamycin, and quinupristin-dalfopristin) as well as those of benzylpenicillin, doxycycline, vancomycin, teicoplanin, levofloxacin, and rifapentine against 247 aerobic and facultative non-spore-forming gram-positive bacilli were determined by an agar dilution met ... | 1998 | 9593121 |
| antibiotic susceptibility testing (agar disk diffusion and agar dilution) of clinical isolates of corynebacterium jeikeium. | thirty-three clinical isolates of corynebacterium jeikeium were examined for susceptibility to 27 antimicrobial drugs with the agar dilution test. sheep-blood-supplemented mueller-hinton agar performed better than wilkins-chalgren agar. disk susceptibility (bauer-kirby) tests were carried out in parallel with 24 of the chemotherapeutic agents. all isolates were susceptible to teicoplanin and vancomycin. all isolates resisted fosfomycin, mupirocin, and trimethoprim-sulfamethoxazole. the isolates ... | 1998 | 9681199 |
| in vitro activities of ketolide hmr 3647, macrolides, and clindamycin against coryneform bacteria. | the in vitro activity of ketolide hmr 3647 against coryneform bacteria isolated from clinical samples was evaluated. except against corynebacterium jeikeium and c. urealyticum, hmr 3647 showed high activity against corynebacterium spp., being more active than 14- and 16-membered macrolides, azithromycin, or clindamycin. hmr 3647 also had high in vitro activity against brevibacterium spp. and listeria monocytogenes. | 1998 | 9835530 |
| otitis media due to corynebacterium jeikeium. | | 1999 | 10357064 |
| in-vitro activity of levofloxacin, ofloxacin and d-ofloxacin against coryneform bacteria and listeria monocytogenes. | the objective of this study was to evaluate the in-vitro activity of levofloxacin, ofloxacin and d-ofloxacin compared with ciprofloxacin, norfloxacin and sparfloxacin against coryneform bacteria and listeria monocytogenes isolated from clinical samples. the following organisms (and number of strains) were studied: corynebacterium jeikeium (20), corynebacterium urealyticum (20), corynebacterium minutissimum (20), corynebacterium striatum (20), corynebacterium amycolatum (30), brevibacterium spp. ... | 1999 | 10404334 |
| a variety of gram-positive bacteria carry mobile mef genes. | the mefe gene codes for a membrane bound efflux protein, which confers resistance to macrolides, and has been identified in streptococcus pneumoniae. a variety of gram-positive organisms were examined. twenty-six isolates of s. pneumoniae carried mefe and were resistant to erythromycin (mic of 2-16 mg/l). two additional isolates of emr s. pneumoniae carried both ermb and mefe(mic of 16-128 mg/l). one micrococcus luteus, one corynebacterium jeikeium, three corynebacterium spp., two viridans strep ... | 1999 | 10459806 |
| changing epidemiology of infections in patients with neutropenia and cancer: emphasis on gram-positive and resistant bacteria. | over the past 3 decades, considerable changes have occurred in the types of bacteria causing infection in febrile patients with neutropenia and cancer. twenty years ago, gram-negative bacteria caused approximately 70% of bloodstream infections. as a probable consequence of long-dwelling intravascular devices, fluoroquinolone prophylaxis, and high-dose chemotherapy-induced mucositis, there has been a shift toward gram-positive coccal bacteremia. in most centers today, approximately 70% of bactere ... | 1999 | 10530434 |
| identification of coryneform bacterial isolates by ribosomal dna sequence analysis. | identification of coryneform bacteria to the species level is important in certain circumstances for differentiating contamination and/or colonization from infection, which influences decisions regarding clinical intervention. however, methods currently used in clinical microbiology laboratories for the species identification of coryneform bacteria are often inadequate. we evaluated the microseq 500 16s bacterial sequencing kit (perkin-elmer biosystems, foster city, calif.), which is designed to ... | 2000 | 10747168 |
| bacterial meningitis in the elderly: an 8-year review of cases in a university hospital. | the clinical and laboratory characteristics of bacterial meningitis in subjects over 59 years-old were evaluated to establish variables related to prognosis. all patients with clinical and laboratory findings of acute meningitis were included. sixty-four episodes in 64 patients were registered. s. pneumoniae was responsible for 19 cases (27.5%); l. monocytogenes - 3; s. aureus - 1; s. bovis - 1; s. agalactie - 1 and corynebacterium jeikeium 1. gram negative bacilli caused seven cases; two cases ... | 1999 | 11097714 |
| in vitro activity of gemifloxacin against contemporary clinical bacterial isolates from eleven north american medical centers, and assessment of disk diffusion test interpretive criteria. | a total of 5499 contemporary clinical bacterial isolates were tested for susceptibility to gemifloxacin and four comparison agents by the broth microdilution method. gemifloxacin activity against enterobacteriaceae was generally comparable to that of ciprofloxacin and trovafloxacin, but because the gemifloxacin susceptible mic breakpoint is lower, the percent susceptible to gemifloxacin was less than that to the other quinolones for some species. all agents were less active against pseudomonas s ... | 2000 | 11146251 |
| corynebacterium jeikeium native valve endocarditis following femoral access for coronary angiography. | we present a unique case of rapidly fatal native aortic-valve endocarditis due to corynebacterium jeikeium, with inoculation as a complication of repeated femoral vascular access for coronary angiography. | 2001 | 11264050 |
| corynebacterium jeikeium bacteremia in bone marrow transplant patients with hickman catheters. | prior studies suggest that corynebacterium jeikeium bacteremia in immunocompromised patients results in frequent morbidity that may be decreased by prompt removal of the indwelling catheter. to summarize recent experience, charts of 53 bone marrow transplant recipients with hickman catheters and c. jeikeium bacteremia were reviewed. forty-one patients were treated with vancomycin without catheter removal and 10 patients underwent catheter removal with subsequent vancomycin therapy. no patient in ... | 2001 | 11313675 |
| [significant bacteremias by corynebacterium amycolatum: an emergent pathogen]. | corynebacterium sp. is an extremely varied genus which includes little known species and of which only corynebacterium diphteriae, corynebacterium urealyticum and corynebacterium jeikeium are considered indisputable pathogens. other species, such as c. amycolatum are at present being reconsidered as causative agents in infectious pathologies, partly on account of our greater aquaintance and improved identification techniques for these microorganisms and partly on account of the growing number of ... | 2001 | 11333587 |