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degradation of lignocellulosic material and humus formation by fungi.cellulase activity and degradation of cellulose and lignin in wheat straw and formation of humus during degradation by aspergillus sp., chaetomium globosum, fusarium solani, paecilomyces varioti, penicillium chrysogenum and trichoderma viride qm9414 were studied. c. globosum, f. solani, p. varioti and p. chrysogenum produced little or no cellulase when grown on cellulose powder. however, all produced cellulase (filter paper degrading activity) when grown on wheat straw. all the cultures degraded ...1979507620
acute toxic effects of chaetoglobosin a, a new cytochalasan compound produced by chaetomium globosum, on mice and rats.a new cytochalasan compound, chaetoglobosin a produced by chaetomium globosum, was studied for its toxicity to animals. by subcutaneous injection, 2 mg/kg body weight of chaetoglobosin a killed young wistar rats acutely, and in the mouse of ddd strain, ld50 values of chaetoglobosin a were estimated 6.5 and 17.8 mg/kg for male and female, respectively. by oral administration, 400 mg/kg of chaetoglobosin a caused little adverse effect on mice and rats. pathological examination of the mice, injecte ...1978713122
cytotoxicity of new cytochalasans from chaetomium globosum. 19751120509
degradation of alachlor by a soil fungus, chaetomium globosum. 19751133282
effect on microorganisms of volatile compounds released from germinating seeds.volatile compounds evolved from germinating seeds of slash pine, bean, cabbage, corn, cucumber, and pea were evaluated for their ability to support growth of microorganisms in liquid mineral salts media lacking a carbon source. growth of eight bacteria was measured turbidimetrically and of six fungi as dry weight of mycelium. volatiles caused increased growth of pseudomonas fluorescens, bacillus cereus, erwinia carotovora, agrobacterium tumefaciens, a. radiobacter, rhizobium japonicum, mucor muc ...19751201509
onychomycosis of the toenails caused by chaetomium globosum. 19921533863
keratinophilic fungi and other moulds associated with air-dust particles from egypt.one-hundred and eleven species and three species varieties belonging to 39 genera were collected from 50 dust samples on the five media used at 28 degrees c. using the hair-baiting technique with horse hair, 10 species of chrysosporium were isolated: c. asperatum, c. state of arthroderma tuberculatum, c. indicum, c. inops, c. keratinophilum, c. merdarium, c. pannorum, c. queenslandicum, c. tropicum and c. xerophilum. true dermatophytes were isolated: trichophyton verrucosum and trichophyton sp. ...19901702081
onychomycosis caused by chaetomium globosum kunze.in this paper we report a case of onychomycosis caused by chaetomium globosum. the patient had lesions of the fingernails of the left hand. the direct microscopical examination of the nails showed light-brown hyphae with thick-walled cells. the histopathological examination revealed thick aggregated hyphal element in the nail plate. amongst the antimycotics tested oxiconazole with mic values of 0.3 microgram/ml-1 was found to be most effective in vitro against chaetomium globosum.19911826539
release of mutagens after chemical or microbial degradation of beech wood lignin.the microbial or chemical degradation of lignin from untreated samples of beech wood dusts (fagus silvatica) resulted in the release of different mutagenic responses in the salmonella/mammalian plate incorporation assay. in the first experiment using chemical degradation of lignin, dust samples were pre-extracted using acetone-water; the lignin portions were degraded into simpler compounds which were further fractionated on a sephadex-lh20 column. the compounds isolated from the second phase of ...19902339441
occurrence of zoosporic and terrestrial fungi in some ponds of kharga oases, egypt.thirty-nine species belonging to 13 genera of zoosporic fungi were collected from 33 water samples on sesame and hemp seeds as baits at 22 degrees c. five genera were isolated in high occurrence: allomyces (2 species), achlya (9 species), dictyuchus (4 species), pythium (5 species) and saprolegnia (5 species). aphanomyces (4 species) and isoachlya (2 species) were of moderate frequencies. the remaining six genera were less frequent: anisolpidium, brevilegnia, calyptralegnia, leptolegnia, pythiop ...19902384873
cerebral phaeohyphomycosis caused by chaetomium globosum in a renal transplant recipient.a 32-year-old male patient developed headaches, vomiting, blurring of vision, and focal seizures of the left side of the face 2 months after a renal transplant. he developed a brain abscess and died. direct koh examination of the brain tissue demonstrated hyaline as well as dematiaceous, septate hyphae. histologic examination of brain sections revealed polymorphous fungal elements consisting of septate, dark-pigmented hyphae, intercalary and terminal swollen fungal cells, and budding yeastlike c ...19892584374
mycoflora of anise and fennel seeds in egypt.using four medium types (glucose-, cellulose-, 50% sucrose- and 10% nacl-czapek's agar), it was possible to isolate 15 fungal genera, 78 species and 6 varieties. the collective fungal spectrum varied from one medium to another where the highest number of species (57 species/1000 seeds) was obtained on glucose- and the lowest (31 species/1000 seeds) on 10% nacl-czapek's agar. aspergillus, penicillium, and sometimes rhizopus and chaetomium were the most common genera on the different medium types. ...19892600777
mycoflora and mycotoxin-producing fungi of air-dust particles from egypt.using the dilution-plate method, 27 genera and 64 species were collected from 20 air-dust samples on glucose - (24 genera and 57 species) and cellulose - (21 genera and 45 species) czapek's agar at 28 degrees c. there are basic similarities between the mycoflora of air-dust on the two media and the most prevalent species were aspergillus niger, a. flavus, a. ochraceus, a. terreus, a. versicolor, penicillium chrysogenum, p. funiculosum, alternaria alternata, cladosporium herbarum, fusarium oxyspo ...19862938009
cutaneous and ungual phaeohyphomycosis caused by species of chaetomium kunze (1817) ex fresenius, 1829.two cases of cutaneous and ungual phaeohyphomycosis caused by species of chaetomium are reported. the patients showed no clinical signs of immunodeficiency. in case 1 there was a small, ulcerated, crusted lesion on the right forearm. direct microscopical examination of material from this lesion showed light-brown hyphae with thick-walled cells. the fungus isolated was identified as chaetomium globosum. case 2 had lesions of the fingernails. direct microscopy showed dematiaceous septate hyphae in ...19883236145
mycoflora of air-conditioners dust from riyadh, saudi arabia.using the hair baiting technique, 6 genera and 14 species were collected on sabouraud's dextrose agar from 37 dust samples from air-conditioners. the most common fungi were chrysosporium tropicum, c. indicum, c. keratinophilum, aspergillus flavus followed by acremonium strictum and scopulariopsis brevicaulis. using the dilution-plate method, 26 genera and 52 species were collected from 37 dust samples on glucose-(23 genera and 45 species) and cellulose-(18 genera and 34 species) czapek's agar at ...19883236219
a bacteriolytic enzyme from chaetomium globosum, a marine-isolate. 19734711457
lipid composition of chaetomium cochliodes: effect of media. 19734713379
[chemical and submicroscopic structure of the cell walls of the ascomycete chaetomium globosum]. 19725058879
sporidesmins. 8. ovine ill-thrift in nova scotia. 3. the characterisation of chetomin a toxic metabolite of chaetomium cochliodes and chaetomium globosum. 19725066072
cell-wall proteins of aspergillus niger and chaetomium globosum. 19695365360
the effect of cochliodinol, a metabolite of chaetomium cochliodes, on the respiration of microsopores of fusarium oxysporum. 19715555523
toxicity to rats of corn invaded by chaetomium globosum.of 53 isolates of chaetomium globosum kunze isolated from corn, manufactured feed, and fiberboard, grown on autoclaved corn, and fed to rats, 25 were lethal within 4 to 6 days. thirty-six single ascospore cultures of one isolate were uniformly lethal when similarly grown and fed to rats. incubation of the fungus on corn for 6 to 8 weeks resulted in greater toxicity than shorter incubation times. premortem symptoms indicated damage to the central nervous system of the affected animals, and postmo ...19665970465
a new sesquiterpene antibiotic, heptelidic acid producing organisms, fermentation, isolation and characterization.a new sesquiterpene antibiotic, heptelidic acid, was found in the culture filtrate of three different strains of fungi isolated from soil samples. these strains were identified as gliocladium virens, chaetomium globosum and trichoderma viride. heptelidic acid was produced by conventional submerged culture and purified by successive column chromatography on silica gel and sephadex lh-20 and finally by preparative tlc on silica gel. the molecular formula of heptelidic acid was determined as c15h20 ...19807191847
pathogenicity and antifungal susceptibility of chaetomium species.several reports have been published implicating chaetomium spp. as opportunistic pathogens. a critical review of these cases was made, and the majority of the responsible strains were studied. chaetomium globosum was the most common species, being isolated in at least nine clinical cases of infection. some of these clinical isolates and others from environmental sources were tested against six antifungal agents (5-fluorocytosine, fluconazole, amphotericin b, itraconazole, ketoconazole and micona ...19957588850
the normal mycoflora of commodities from thailand. 1. nuts and oilseeds.a comprehensive study was carried out of the fungi occurring in commodities normally traded in thailand. samples of major commodities were obtained from farmers' stocks and middlemen in major producing areas throughout the country. retail samples were obtained from outlets in and around bankok. samples were divided into two portions, one being examined in bangkok, and the second in sydney. after surface disinfection, fungi were enumerated by direct plating on dichloran rose bengal chloramphenico ...19938110599
azaphilones inhibit tumor promotion by 12-o-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mice.monascorubrin (an azaphilone derivative) was isolated from monascus anka, 'monascus pigment', a natural pigment of food additivies, was extracted from monasucs spp., and chaetoviridin a, one of the azaphilones, was isolated from chaetomium globosum var. flavo-viridae. application of 1 microgram of 12-o-tetradecanoylphorbol-13-acetate (tpa), a tumor promoting agent, to the mouse ear resulted in induction of inflammation. among monascorubrin and related compounds assayed, monascorubrin, chaetoviri ...19948265094
growing incidence of cutaneous and ungual infections by non-dermatophyte fungi at jabalpur (m.p.).a random survey of skin and nail infections was done at jabalpur (m.p.). out of the 80 suspected cases 60 were culture positive. out of these 25 were of dermatophyte infection followed by 21 cases of phaeohyphomycosis, 7 of aspergillosis, 4 of hyalohyphomycosis, 2 of mixed infection in which a non-dermatophyte was associated with a dermatophyte and 1 had yeast infection. trichophyton rubrum was the only dermatophyte isolated. among the non-dermatophyte infections cases of alternaria chlamydospor ...19938276472
mycoflora and natural occurrence of mycotoxins in tobacco from cigarettes in egypt.forty-two species and 4 varieties belonging to 21 genera were collected from 40 tobacco samples on glucose- and cellulose-czapek's agar at 28 degrees c and 45 degrees c. the most common mesophiles (at 28 degrees c) in tobacco on the two types of media were: aspergillus flavus, a. flavus var. columnaris, a. fumigatus, a. niger, penicillium chrysogenum and p. funiculosum. two samples were heavily contaminated with members of fusarium (f. moniliforme, f. oxysporum, f. solani). some fungi were encou ...19938368025
fatal cerebral mycoses caused by the ascomycete chaetomium strumarium.three cases of fatal cerebral mycosis in males with prior histories of intravenous drug use from the united states and australia are reported. infection in each case was limited to brain abscess; no other sites of infection were observed. the fungus seen by histopathology and isolated from the brain tissue in each case was identified as chaetomium strumarium. this is the first report of human infection by this species, and c. strumarium is the second species of chaetomium known to cause primary ...19958567907
chaetomium pneumonia in patient with acute myeloid leukaemia.a patient with relapsed refractory acute myeloid leukaemia developed typical fungal lung lesions despite intravenous amphotericin b prophylaxis. chaetomium globosum was cultured from the resected right lower lobe. histology showed branching hyphae negative for common aspergillus species by immunohistochemical staining. previous reports of invasive disease caused by chaetomium and some applications of immunohistochemical staining for aspergillus are discussed.19968655695
endoglucanase production by paper-degrading mycoflora.fourteen fungal species, namely aspergillus flavus, a. fumigatus, a. niger, a. ustus, penicillium islandicum, p. wortmannii, memnoniella echinata, cladosporium herbarum, stachybotrys atra, chaetomium globosum, fusarium oxysporum, torula herbarum, alternaria alternata and curvularia uncinata were isolated from different grades of paper. they differ in their distribution on various kinds of paper and also in relative occurrence. while seasonal influence on mycoflora was observed, most of the mould ...19979418063
possible role of chaetomium globosum in infection after autologous bone marrow transplantation. 199910051093
space flight micro-fungi after 27 years storage in water and in continuous culture.four species of micro-fungi were selected for study in the national aeronautics and space administration (nasa) apollo microbial ecology evaluation device (meed) mycology experiments. trichophyton terrestre, rhodotorula rubra, saccharomyces cerevisiae and chaetomium globosum were selected from a series of preflight test fungi for the meed mycology studies during the 2 years prior to the actual flight (volz, 1971a, 1972b). conidia of t. terrestre, ascospores of c. globosum and yeast cells of r. r ...199810093232
effect of vapor phase corrosion inhibitor on microbial corrosion of aluminum alloys.vapor phase corrosion inhibitors were used to investigate the antimicrobial activities and anticorrosion of aluminum alloy. aspergillus flavus, a. niger, a. versicolor, chaetomium globosum and penicillium funiculosum had moderate to abundant growth on the aluminum alloy aa 1100 at aw 0.901, while there was less growth at aw 0.842. high humidity stimulated microbial growth and induced microbial corrosion. dicyclohexylammonium carbonate had a high inhibitory effect on the growth of test fungi and ...199610592784
mycoflora and mycotoxins of brazilian cashew kernels.kernel samples of common and dwarf brazilian cashew nuts were highly contaminated with field and storage fungi in comparison to healthy ones. in general, dwarf cashews were more contaminated than common. a total of 37 fungal species were identified. aspergillus niger was the dominant species with more colonies being isolated from dwarf kernels. a. flavus was the next most frequently isolated species. penicillium brevicompactum, and p. glabrum were the most frequently isolated penicillia, with hi ...199910598070
case report. onychomycosis due to chaetomium globosum successfully treated with itraconazole.we have experienced a case of toenail infection caused by chaetomium globosum which we treated with itraconazole 100 mg day-1 for 6 months, after which time the nail lesions were almost cured. our case is the first reported case of onychomycosis caused by ch. globosum in japan, and the seventh in the world.200010838856
mycoflora and mycotoxins in brazilian black pepper, white pepper and brazil nuts.a wide range of field and storage fungi were isolated from black pepper, white pepper and brazil nut kernels from amazonia. a total of 42 species were isolated from both peppers. aspergillus flavus and a. niger were isolated more frequently from black than from white pepper. other potential mycotoxigenic species isolated included: a. ochraceus, a. tamarii, a. versicolor, emericella nidulans and chaetomium globosum, penicillium brevicompactum, p. citrinum, p. islandicum and p. glabrum. species is ...200011229375
growth of chitinolytic dune soil beta-subclass proteobacteria in response to invading fungal hyphae.it has frequently been reported that chitinolytic soil bacteria, in particular biocontrol strains, can lyse living fungal hyphae, thereby releasing potential growth substrate. however, the conditions used in such assays (high bacterial density, rich media, fragmented hyphae) make it difficult to determine whether mycolytic activity is actually of importance for the growth and survival of chitinolytic bacteria in soils. an unidentified group of beta-subclass proteobacteria (cbetaps) was most domi ...200111472904
do stable isotopes reflect the food web development in regenerating ecosystems?we evaluated the use of delta15n- and delta13c-values to monitor the development of food web complexity and biodiversity in a regenerating ecosystem. therefore a model food chain was established feeding cultivated woodlice (porcellio dilatatus) on a cellulolytic fungus (chaetomium globosum) grown on cellulose paper. two diets of different quality (c:n ratios of 54 vs. 200) with different delta15n- (1.3% vs. 3.1%) but identical delta13c-values caused low and high dietary stress in animals of trea ...200011501706
[effect of chaetomium cochliodes palliser on micromycetes of the root zone of spring barley].the paper deals with the studies in species composition of micromycetes of the meadow-chernozem deleached soil in the root zone of spring barley and their interaction with the strain of fungus-antagonist chaetomium cochliodes 3250, which served a basis for creation of the preparation--chetomik to protect plants from the root diseases agents. differences were established between mycobiota of soil and root zone of plants; the most considerable ones are the differences between soil rhizoplane: the ...200111785418
comparative degradation of oomycete, ascomycete, and basidiomycete cell walls by mycoparasitic and biocontrol fungi.fourteen fungi (primarily representing mycoparasitic and biocontrol fungi) were tested for their ability to grow on and degrade cell walls (cws) of an oomycete (pythium ultimum), ascomycete (fusarium equisetii), and basidiomycete (rhizoctonia solani), and their hydrolytic enzymes were characterized. protein was detected in the cultural medium of eleven of the test isolates, and these fungi significantly degraded cws over the 14-day duration of the experiment. in general, a greater level of cw de ...200211888164
antimycobacterial anthraquinone-chromanone compound and diketopiperazine alkaloid from the fungus chaetomium globosum kmitl-n0802.investigation of the fungus chaetomium globosum kmitl-n0802 led to the isolation of a novel anthraquinone-chromanone compound named chaetomanone along with seven known compounds, ergosterol, ergosteryl palmitate, chrysophanol, chaetoglobosin c, alternariol monomethyl ether, echinuline and isochaetoglobosin d. these compounds were characterized by spectroscopic methods. chaetomanone and echinulin exhibited activity towards mycobacterium tuberculosis.200212357398
phytotoxic chaetoglobosins are produced by the plant pathogen calonectria morganii (anamorph cylindrocladium scoparium).by the application of a bioassay based on cresson seedlings, two phytotoxic compounds were isolated by thin-layer chromatography from the culture fluid of a calonectria morganii isolate. the structure of both compounds was elucidated by esi/ms and nmr spectroscopy. according to the chemical abstracts database, they were identified as chaetoglobosin a and 19-o-acetylchaetoglobosin a, mycotoxins originally described for chaetomium globosum.200112483566
use of gas chromatography-mass spectrometry/solid phase microextraction for the identification of mvocs from moldy building materials.gas chromatography-mass spectrometry/solid phase microextraction (gc-ms/spme) was applied to identify microbial volatile organic compounds (mvocs) in water-damaged, mold-infested building materials (gypsum board papers (n=2), mineral wool, and masonite) and in cultivated molds (aspergillus penicillioides, stachybotrys chartarum, and chaetomium globosum). three spme fibers (65-microm pdms-dvb, 75-microm carboxen-pdms, and 70-microm carbowax-stableflex) designed for automated injection were used o ...200312531501
survival of filamentous fungi in hypersaline dead sea water.a variety of filamentous fungi have recently been isolated from the dead sea (340 g/l total dissolved salts). to assess the extent to which such fungi can survive for prolonged periods in dead sea water, we examined the survival of both spores and mycelia in undiluted dead sea water and in dead sea water diluted to different degrees with distilled water. mycelia of aspergillus versicolor and chaetomium globosum strains isolated from the dead sea remained viable for up to 8 weeks in undiluted dea ...200312545316
microbial community composition affects soil fungistasis.most soils inhibit fungal germination and growth to a certain extent, a phenomenon known as soil fungistasis. previous observations have implicated microorganisms as the causal agents of fungistasis, with their action mediated either by available carbon limitation (nutrient deprivation hypothesis) or production of antifungal compounds (antibiosis hypothesis). to obtain evidence for either of these hypotheses, we measured soil respiration and microbial numbers (as indicators of nutrient stress) a ...200312571002
detection of viable fungal spores contaminant on documents and rapid control of the effectiveness of an ethylene oxide disinfection using atp assay.filamentous fungi are able to damage and even destroy archival and library materials. nowadays the conventional method for detecting such micro-organisms is to put them in cultures but such methods are laborious and time-consuming. atp methodology has been widely applied in other domains and its success on bacteria and yeast has been demonstrated. several commercial reagent kits are available but they did not give satisfactory results on spores mould. we have elaborated new extraction strategies ...200312687632
purification and some properties of exo-1,4-beta-glucanase from chaetomium olivaceum.exo-1,4-beta-glucanase (e.c. 3.2.1.91) was successively purified by precipitation with acetone, followed by gel filtration on sephadex g-100 and chromatographed onto deae-cellulose. a typical procedure provided 47.14 fold purification with 72.8% yield. the molecular mass of the purified enzyme was found to be 88 kda by sds-page. the ph optimum of the enzyme was 5.2 and maximum activity was obtained at 45 degrees c. km value against alpha-cellulose was 0.65 mg ml(-1). alpha-cellulose and filter p ...200312916726
the influence of hexose phosphates, calcium and jute extract on the formation of perithecia by chaetomium globosum. 195313044913
control of a seed-borne disease by chaetomium cochlioides pall., under natural conditions. 195313072567
synthesis of beta-linked glucosaccharides by extracts of chaetomium globosum. 195413230102
the production of beta-linked glucose saccharides from cellobiose by chaetomium globosum. 195613315328
the influence of certain micro-organisms on the formation of perithecia by chaetomium globosum. 195613346026
the effect of a physical barrier on sporulation of chaetomium globosum. 195613357727
[presence of orsellinic acid in chaetomium cochliodes]. 195913648641
in vitro activities of new antifungal agents against chaetomium spp. and inoculum standardization.chaetomium is an unusual etiological agent of human infections, but the mortality rate among immunocompromised patients is considerably greater than that among nonimmunocompromised individuals. we investigated the in vitro antifungal susceptibilities to novel antifungal agents of 19 strains belonging to three species of chaetomium which have been involved in human infections, i.e., chaetomium globosum, c. atrobrunneum, and c. nigricolor, and one strain of the closely related species achaetomium ...200314506025
mould specific igg antibodies connected with sinusitis in teachers of mould damaged school: a two-year follow-up study.the aim of this study was to describe the relationship between mould exposure induced by moisture damage and mould specific immunoglobulin g antibodies to 20 common mould species and their association with respiratory diseases.200314587535
phaeohyphomycosis caused by chaetomium globosum in an allogeneic bone marrow transplant recipient.bone marrow transplant recipients are highly susceptible to opportunistic fungal infections. this is the report, of the first case of a chaetomium systemic infection described in brazil. a 34 year-old patient with chronic myeloid leukemia underwent an allogeneic sibling matched bone marrow transplant. seven months later, he developed systemic infection with enlargement of the axillary and cervical lymph nodes. culture of the aspirates from both lymph nodes yielded chaetomium globosum. the infect ...200314682456
significance of calcium in the fruiting of chaetomium species, particularly chaetomium globosum. 195114832409
further observations on the sporulation of chaetomium globosum. 195114908014
culturability and toxicity of sick building syndrome-related fungi over time.two experiments were conducted regarding the culturability and toxicity of fungi located on building materials over time and the efficacy of seven laboratory techniques in recovering culturable fungi from sample swabs. in the first experiment, eight sections of drywall were inoculated with stachybotrys chartarum and stored at 25 +/- 5 degrees celsius and 20-60% relative humidity (rh) for up to two years. another eight sections of ceiling tile were stored at 100% rh for 1 year. six sections of ce ...200415238302
an investigation into techniques for cleaning mold-contaminated home contents.this study examined the efficacy of the following treatments to reduce selected fungal spore and mycotoxin levels on materials commonly found in home contents: (1) gamma irradiation at a 10-13 kilogray exposure, (2) a detergent/bleach wash, and (3) a steam cleaning technique. a minimum of six replicates were performed per treatment. paper, cloth, wood, and carpet were inoculated with either fungal spores (stachybotrys chartarum, aspergillus niger, penicillium chrysogenum, or chaetomium globosum) ...200415238314
the sirodesmin biosynthetic gene cluster of the plant pathogenic fungus leptosphaeria maculans.sirodesmin pl is a phytotoxin produced by the fungus leptosphaeria maculans, which causes blackleg disease of canola (brassica napus). this phytotoxin belongs to the epipolythiodioxopiperazine (etp) class of toxins produced by fungi including mammalian and plant pathogens. we report the cloning of a cluster of genes with predicted roles in the biosynthesis of sirodesmin pl and show via gene disruption that one of these genes (encoding a two-module non-ribosomal peptide synthetase) is essential f ...200415387811
chaetoglobosins q, r, and t, three further new metabolites from chaetomium globosum.nine cytotoxic metabolites, including three novel compounds, chaetoglobosins q (1), r (2), and t (3), have been isolated from cultures of the fungus chaetomium globosum. the structures were elucidated primarily from nmr spectroscopic data.200415497948
bioconversion of (+)-valencene in submerged cultures of the ascomycete chaetomium globosum.submerged cultures of the ascomycete chaetomium globosum oxidised the exogenous sesquiterpene (+)-valencene to nootkatone via the stereoselective generation of alpha-nootkatol. inhibition experiments suggested that the first introduction of oxygen, the rate-limiting step of the bioconversion, may have been catalysed by a cytochrome-p450-monooxygenase. however, nootkatone was not the final metabolite: further flavour-active and inactive, non-volatile oxidation products were identified. (+)-valenc ...200415602686
molecular confirmation of invasive infection caused by chaetomium globosum. 200515735175
[agrobacterium tumefaciens-mediated transformation of chaetomium globosum and its t-dna insertional mutagenesis].agrobacterium tumefaciens-mediated transformation is a routine method in the genetic transformation of a wide range of plant species, and so far, its application has been extended to the transformation of yeasts, fungi and even human cells. by using this transformation system, filamentous fungus chaetomium globosum was successfully transformed with an efficiency of 60-180 transformants per 10(7) spores. pcr and southern analysis showed that the t-dna was integrated into the genome. among of the ...200515847179
virulence of fungal spores determined by tracheal inoculation of goats following inhalation of aerosolized sterile feedyard dust.to compare the virulence of spores of 7 fungi by tracheal inoculation of goats following exposure of goats to an aerosol of sterilized feedyard dust. animals-54 weanling boer-spanish goats.200515900941
globosumones a-c, cytotoxic orsellinic acid esters from the sonoran desert endophytic fungus chaetomium globosum.three new esters of orsellinic acid, globosumones a-c (1-3), and three known compounds, orsellinic acid (4), orcinol, and trichodion (5), were isolated from chaetomium globosum endophytic on ephedrafasciculata (mormon tea). the structures of the new compounds 1-3 were established spectroscopically, which included 2d nmr experiments and 1h nmr studies on mosher's ester derivatives. all compounds were evaluated for inhibition of cell proliferation in a panel of four cancer cell lines, nci-h460 (no ...200515921417
determination of microbial volatile organic compounds adsorbed on house dust particles and gypsum board using spme/gc-ms.adsorption of microbial volatile organic compounds (mvocs) on house dust was analyzed by performing solid phase microextraction (spme) in combination with gas chromatography-mass spectrometry (gc-ms). settled dust samples were exposed to five selected mvocs and to cultures of the molds stachybotrus chartarum, aspergillus versicolor, and chaetomium globosum. considerable desorption of the mvocs adsorbed on the dust occurred spontaneously within a few hours at room temperature and within several d ...200515954244
[endophytic fungi in rose (rosa hybrida) in bogota, colombia].we have investigated the presence of endophytic fungi associated with rose plants (rosa hybrida) in colombia. endophytic fungi were isolated from healthy leaves of ten ornamental roses plants from gardens cultured in malt extract, peptone, yeast extract agar plates (mpy). we sampled 560 leaves fragments, 56 per sample. endophytic fungi comprised 92 isolates (16.4%); of these isolates, 41 were classified as sterile mycelium (without reproductive structures that allowed their identification), 31 i ...200516107167
effect of chlorine dioxide gas on fungi and mycotoxins associated with sick building syndrome.the growth of indoor molds and their resulting products (e.g., spores and mycotoxins) can present health hazards for human beings. the efficacy of chlorine dioxide gas as a fumigation treatment for inactivating sick building syndrome-related fungi and their mycotoxins was evaluated. filter papers (15 per organism) featuring growth of stachybotrys chartarum, chaetomium globosum, penicillium chrysogenum, and cladosporium cladosporioides were placed in gas chambers containing chlorine dioxide gas a ...200516151130
in-vessel composting of household wastes.the process of composting has been studied using five different types of reactors, each simulating a different condition for the formation of compost; one of which was designed as a dynamic complete-mix type household compost reactor. a lab-scale study was conducted first using the compost accelerators culture (trichoderma viridae, trichoderma harzianum, trichorus spirallis, aspergillus sp., paecilomyces fusisporus, chaetomium globosum) grown on jowar (sorghum vulgare) grains as the inoculum mix ...200616153815
analysis of an effective antibiotic (chaetomacin) isolated from a thermophilic bacillus sp. against olive green mold.successful methods to control the damaging weed mold chaetomium olivaceum (olive green mold) in mushroom beds are not known. an effective antibiotic (named chaetomacin) against c. olivaceum was isolated from a thermophilic bacillus sp. this compound was shown to be an extremely potent and stable antibiotic, effective over a wide range of both ph (2 to 10) and temperature (-15 to 150 degrees c). chaetomacin is soluble in most polar solvents and insoluble in nonpolar solvents. it is produced only ...198416346515
degradation of wood preservatives by fungi.wood-inhabiting fungi, not necessarily responsible for major decay, are shown to be capable of degrading a toxic compound into a less potent form, thus rendering it less effective in protecting wood from decay by less-tolerant basidiomycetous wood-destroyers. sweetgum or pine sapwood blocks treated with preservatives (ammoniacal copper arsenate, fluor-chrome-arsenate-dinitrophenol, a creosote or pentachlorophenol) were exposed progressively to two different wood-inhabiting fungi with sterilizati ...196416349644
chaetoglobosin u, a cytochalasan alkaloid from endophytic chaetomium globosum ifb-e019.a new cytotoxic cytochalasan-based alkaloid named chaetoglobosin u (1), along with four known analogues, chaetoglobosins c (2), f (3), and e (5) and penochalasin a (4), has been characterized from the etoac extract of a solid culture of chaetomium globosum ifb-e019, an endophytic fungus residing inside the stem of healthy imperata cylindrica. the structure of chaetoglobosin u was determined through correlative analyses of its uv, ir, cd, ms, and 1d ((1)h and(13)c nmr and dept) and 2d nmr (cosy, ...200616499339
a study of oxygen absorption and catalase production during growth of chaetomium globosum on cotton fiber and yarn. 194216560491
chaetomin, a new antibiotic substance produced by chaetomium cochliodes: i. formation and properties. 194416560863
chaetomin, a new antibiotic substance produced by chaetomium cochliodes: ii. isolation and concentration. 194416560864
development of aflp-derived, functionally specific markers for environmental persistence studies of fungal strains.the ability to rapidly identify and quantify a microbial strain in a complex environmental sample has widespread applications in ecology, epidemiology, and industry. in this study, we describe a rapid method to obtain functionally specific genetic markers that can be used in conjunction with standard or real-time polymerase chain reaction (pcr) to determine the abundance of target fungal strains in selected environmental samples. the method involves sequencing of randomly cloned aflp (amplified ...200616699570
chemokine receptor ccr-5 inhibitors produced by chaetomium globosum.two novel chemokine receptor ccr-5 inhibitors, sch 210971 (1) and sch 210972 (2), were isolated from the fungal fermentation broth of chaetomium globosum by normal- and reversed-phase hplc purifications. the structure determination of 1 and 2 was accomplished on the basis of uv, ms, and nmr spectral data analyses including cosy, noesy, hmqc, and hmbc experiments. the structure and relative configuration of 2 were determined unequivocally by x-ray crystallographic analysis. the major component 2 ...200616872138
a new dihydroxanthenone from a plant-associated strain of the fungus chaetomium globosum demonstrates anticancer activity.bioassay-guided fractionation of a cytotoxic etoac extract of the fungal strain, chaetomium globosum, inhabiting the rhizosphere of the christmas cactus, opuntia leptocaulis, of the sonoran desert afforded a new dihydroxanthenone, globosuxanthone a (1), a new tetrahydroxanthenone, globosuxanthone b (2), two new xanthones, globosuxanthone c (3) and d (4), 2-hydroxyvertixanthone (5), and two known anthraquinones (6 and 7). the structures of the new compounds 1-4 were elucidated by nmr and ms techn ...200616904330
characterization of fungi from hypersaline environments of solar salterns using morphological and molecular techniques.the cabo rojo solar salterns located on the southwest coast of puerto rico are composed of two main ecosystems (i.e., salt ponds and microbial mats). even though these locations are characterized by high solar radiation (mean light intensity of 39 mol photons m-2d-1) they harbour a diverse microscopic life. we used morphological and molecular techniques to identify a series of halotolerant fungi. a total of 183 isolates and 36 species were cultured in this study. from the water from the salt pon ...200616904880
a case of subcutaneous phaeohyphomycosis caused by chaetomium globosum and the sequences analysis of c. globosum.a 14-year-old boy developed painful erythema and necrosis on his face with petechia on his upper extremities. microscopically, necrotic tissue treated with potassium hydroxide showed branched, dematiaceous, septate hyphae. chaetomium globosum was isolated repeatedly from the necrotic tissues. morphology and thermotolerance test of the pathogen were also studied. the internal transcribed spacer region in rrna gene was amplified and sequenced. the sequence of this patient matched well with that of ...200616966171
chaetopyranin, a benzaldehyde derivative, and other related metabolites from chaetomium globosum, an endophytic fungus derived from the marine red alga polysiphonia urceolata.cultivation of the endophytic fungus chaetomium globosum, which was isolated from the inner tissue of the marine red alga polysiphonia urceolata, resulted in the isolation of chaetopyranin (1), a new benzaldehyde secondary metabolite. ten known compounds were also isolated, including two benzaldehyde congeners, 2-(2',3-epoxy-1',3'-heptadienyl)-6-hydroxy-5-(3-methyl-2-butenyl)benzaldehyde (2) and isotetrahydroauroglaucin (3), two anthraquinone derivatives, erythroglaucin (4) and parietin (5), fiv ...200617125234
association between sensitization to aureobasidium pullulans (pullularia sp) and severity of asthma.recent data indicate that fungi may contribute to increased severity of asthma.200717304882
study on the diversity of endophytic communities from rice (oryza sativa l.) and their antagonistic activities in vitro.endophytic populations were isolated from 2400 segments of oryza sativa collected from bhadra river project area, southern india during december 2005 (winter) and april 2006 (summer). overall colonization rates from surface sterilized tissues were 40.3% in roots and 25.83% in leaves during winter season, 20.15% in roots and 8.66% in leaves during summer season. nineteen different fungal taxa, a streptomyces sp. and bacterial species were isolated. streptomyces sp., chaetomium globosum, penicilli ...200917433644
electrospray tandem mass spectrometry of epipolythiodioxopiperazines.low-energy collision-induced electrospray ionization tandem mass spectrometry esi-cid-ms/ms (in the positive ion mode) was used for the structural characterization of a series of five representative epioplythiodioxopipreazines: dethiotetra(methylthio)chemotin, chaetocochins a, b and c, and chemotin isolated from the fungus chaetomium cochliodes. the fragmentation pathways were elucidated by esi-it-ms(n). the elemental compositions of most of the product ions were confirmed by low-energy esi-cid- ...200717492721
sch 213766, a novel chemokine receptor ccr-5 inhibitor from chaetomium globosum.a novel fungal secondary metabolite, sch 213766 was isolated from the fungal fermentation broth of chaetomium globosum as the chemokine receptor ccr-5 inhibitor and shown to be the methyl ester of the previously described tetramic acid sch 210972 on the basis of uv, ms and nmr spectral data analyses. sch213766 exhibited an ic(50) value of 8.6 mum in the ccr-5 receptor in vitro binding assay.200717827664
effect of selected natural dyes in reduction on colour changes of egyptian linen textiles by fungi.linen is the most historical egyptian textile fibre liable to fungal deterioration. fungal deterioration of dyed linen textiles may appear as undesirable different stains. in order to success in removing of fungal stains from biodeteriorated historical egyptian dyed linen textiles, it is necessary to understand the nature and causes of these stains, hence their subsequent removal. so this paper aims to investigate the effect of fungi on dyed linen textiles. in this study linen textile samples we ...200717867537
production of lethal mutations in the fungus chaetomium globosum by monochromatic ultraviolet irradiation. 194918120002
chetomin an antibiotic substance from chaetomium cochliodes; composition and functional groups. 194918124507
mutants produced by x-irradiation of spores of chaetomium globosum and a comparison with those produced by ultraviolet irradiation.1. mutants produced by x-irradiation of fungal spores of chaetomium globosum have been compared with those produced by ultraviolet irradiation. 2. the most striking difference between the mutants produced by x-irradiation and ultraviolet irradiation is the absence in x-ray experiments of the k mutant which is produced in large numbers at short ultraviolet wave lengths. 3. a comparison is made of the relation between x-ray dose and numbers of lethal mutants, and the relation between the short ult ...194918131868
evidence for horizontal transfer of a secondary metabolite gene cluster between fungi.filamentous fungi synthesize many secondary metabolites and are rich in genes encoding proteins involved in their biosynthesis. genes from the same pathway are often clustered and co-expressed in particular conditions. such secondary metabolism gene clusters evolve rapidly through multiple rearrangements, duplications and losses. it has long been suspected that clusters can be transferred horizontally between species, but few concrete examples have been described so far.200818218086
prevalence of allergic sensitization to indoor fungi in west virginia.exposure to indoor fungi is of growing concern in residential and occupational environments in the united states. the purpose of this study was to determine the prevalence of sensitization to common indoor fungal species in an atopic population. we evaluated 102 patients (73 female and 29 male patients) for immunoglobulin e (ige) reactivity to a panel of skin-prick test (spt) reagents used for routine allergy testing. patients also were tested for six additional fungi that are common indoor cont ...200818302835
contamination of peritoneal dialysis fluid by filamentous fungi.peritonitis is a frequent complication in peritoneal dialysis. it may be caused by contamination of the dialysis tubing or by extension of the catheter exit site. gram-positive bacteria are the most common organism, accounting for 60% of all documented cases of continuous ambulatorial peritonitis dialysis. fungi are isolated from to 1-15% of cases. forty-nine out of 490 bottles containing fluid for peritoneal dialysis were randomly selected for microbiological analysis in são paulo, brazil. in t ...199918473556
endophytic fungal diversity of 2 sand dune wild legumes from the southwest coast of india.endophytic fungi of 3 age classes (seeds, seedlings, and mature plants) and 5 tissue classes (cotyledons, seed coats, roots, stems, and leaves) of coastal sand dune legumes canavalia cathartica and canavalia maritima were assessed by plating surface-sterilized segments on malt extract agar. forty-six fungal taxa comprising 6 ascomycetes, 33 mitosporic fungi, 2 zygomycetes, and 5 sterile morphospecies were recovered. there was no significant difference in the colonization frequency of endophytes ...200415714232
three isolations of chaetomium globosum from erythematous epilation of canine skin.chaetomium globosum is commonly found in natural environments worldwide and is known to be a causative agent for emerging fungal infections. the present study describes a case of erythematous epilation of a dog caused by c. globosum. a mixed-breed young dog, a 4-months-old male, weighing 7.25 kg, showed depilation, scales, and dermatitis with slightly itchiness on his skin. the main symptom was an erythematous epilation on the left subocular skin 7.5 cm in diameter, accompanied by elephantiasis- ...200818608918
interactions between nematophagous fungi and consequences for their potential as biological agents for the control of potato cyst nematodes.the efficacies of three nematophagous fungi, paecilomyces lilacinus, plectosphaerella cucumerina and pochonia chlamydosporia, for controlling potato cyst nematodes (pcn) as part of an integrated pest management (ipm) regime were studied. the compatibility of the nematophagous fungi with commonly used chemical pesticides and their ability to compete with the soil fungi rhizoctonia solani, chaetomium globosum, fusarium oxysporum, penicillium bilaii and trichoderma harzianum were tested in vitro. p ...200312735243
[mass development of stachybotrys chartarum on compostable plant pots made from recycled paper].after handling plants grown in decomposable pots made of recycling paper, three women working in a big horticulture developed very painful inflammated efflorescences at the finger-tips, followed by scaling off the skin. the pots appeared to be very mouldy. black masses of conidia of stachybotrys chartarum and perithecia of chaetomium globosum were identified on almost every pot. apart from various other fungal genera, trichoderma und acremonium were frequently detected. considering the observed ...19979417508
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