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a case of prosthetic valve endocarditis caused by corynebacterium hofmanni and candida albicans.the case is described of a 49-year-old woman who developed endocarditis in relation to the prosthetic valve two months after insertion of a starr-edwards mitral valve prosthesis. initially corynebacterium hofmanni was isolated from blood culture. later, while the patient was receiving antibacterial chemotherapy, candida albicans was also isolated and she was treated with 5-fluorocytosine. a cure was effected without the need for further valve replacement.19751191436
corynebacterium hofmanni bacterophage criterion in the taxonomy of corynebacterium genus. 19751227442
corynebacterium pseudodiphtheriticum pulmonary infection in aids patients. 19921351980
leucine dehydrogenase from corynebacterium pseudodiphtheriticum: purification and characterization.leucine dehydrogenase [ec 1.4.1.9] was purified to homogeneity from corynebacterium pseudodiphtheriticum icr 2210. the enzyme consisted of a single polypeptide with a molecular weight of about 34,000. stepwise edman degradation provided the n-terminal sequence of the first 24 amino acids, and carboxypeptidase y digestion provided the c-terminal sequence of the last 2 amino acids. although the enzyme catalyzed the reversible deamination of various branched-chain l-amino acids, l-valine was the be ...19901368565
molecular epidemiology of nasopharyngeal corynebacteria in healthy adults from an area where diphtheria vaccination has been extensively practiced.in addition to conventional biochemical tests, a dna probe specific for corynebacterium diphtheriae was used to characterize 53 cystinase-positive and urease-negative corynebacteria strains isolated from pharyngeal and nasal swabs obtained from 515 healthy adults living in an urban area of central italy. no corynebacterium diphtheriae strain was found. six "atypical" strains were isolated, which could not be classified in any of the species so far defined in the corynebacterium genus. these stra ...19921397226
[four cases of respiratory tract infections caused by corynebacterium pseudodiphtheriticum].four cases of respiratory tract infections caused by corynebacterium pseudodiphtheriticum were reported. the first two patients developed pneumonia with corynebacterium pseudodiphtheriticum during steroid therapy used against their underlying diseases. the other two patients had acute exacerbation of chronic pulmonary diseases caused by c. pseudodiphtheriticum. these four patients improved by antibiotic therapy. though nondiphtheria corynebacteria are regarded as "normal flora" when they are iso ...19921402067
native valve endocarditis due to corynebacterium pseudodiphtheriticum. 19921457649
corynebacterium pseudodiphtheriticum pneumonitis in a leukaemic child.a 6 year old boy receiving chemotherapy for acute lymphocytic leukaemia developed pneumonia due to corynebacterium pseudodiphtheriticum. he responded to antibiotics.19921481190
endocarditis due to corynebacterium pseudodiphtheriticum: five case reports, review, and antibiotic susceptibilities of nine strains.five cases of endocarditis due to corynebacterium pseudodiphtheriticum are described. two patients died, two patients with prosthetic valve endocarditis were successfully treated with antibiotics and valve replacement, and one patient with native valve endocarditis was successfully treated with penicillin alone. we also review 12 previously reported cases of c. pseudodiphtheriticum endocarditis. in vitro susceptibilities to 15 antibiotics were determined for nine isolates. the minimum inhibitory ...19911962103
tracheobronchitis due to corynebacterium pseudodiphtheriticum.we have presented a case of tracheobronchitis due to c pseudodiphtheriticum in a patient with copd who was treated with prednisone and apparently was not otherwise immunocompromised. chronic lung disease seems to predispose to infection with c pseudodiphtheriticum; it can also occur in the immunocompetent host. this organism, when isolated in pure culture, should not be dismissed as a contaminant, but must be considered a possible etiologic agent. sensitivity of diphtheroids to antibiotics is ex ...19912014440
necrotizing tracheitis caused by corynebacterium pseudodiphtheriticum: unique case and review.the occasional pathogenicity of nondiphtheria corynebacteria in both immunocompetent and immunocompromised individuals is now well established. previously described sites of infection include heart valves, wounds, urinary tract, and lungs. this report of necrotizing tracheitis caused by corynebacterium pseudodiphtheriticum illustrates the widening spectrum of infections caused by these organisms. a 54-year-old man developed respiratory distress and symptoms of upper airway obstruction unresponsi ...19912017636
pneumonia caused by corynebacterium pseudodiphtheriticum. 19912067374
the risk of intentional dissolution of the smear layer after mechanical preparation of root canals.the root canals of 27 caries-free human cuspids were divided into 3 groups of 9 teeth each. group i was mechanically prepared with reamers and files. alternate irrigation with 5.25% naocl and 3% hydrogen peroxide was used between each instrument. the group ii root canals were prepared with the use of alternate irrigation with the same concentrations of naocl and hydrogen peroxide and finally flushed with 17% edta and naocl solution. group iii was prepared mechanically with the use of sterile dis ...19902115155
a case of bovine valvular endocarditis caused by corynebacterium pseudodiphtheriticum. 19902301113
[role of normal microflora in the throat in inhibition of adherence of pathogenic bacteria to host cells: in vitro competitive adherence between corynebacterium pseudodiphtheriticum and branhamella catarrhalis].our previous study showed the occurrence of branhamella catarrhalis (b. catarrhalis) pulmonary infections which varies seasonally. to investigate the role of normal throat microflora in this seasonal variation of the occurrence of b. catarrhalis infection, seventy seven throat cultures were done in 45 patients with chronic pulmonary diseases from january to december in 1985. the isolation rate of corynebacterium species as normal microflora was relatively higher in summer than in winter. therefo ...19892501428
origin and fate of ige-bearing lymphocytes. ii. modulation of ige isotype expression on peyer's patch cells by feeding with certain bacteria and bacterial cell wall components or by thymectomy.mechanisms regulating the appearance of sige+ b lymphocytes appear to be lacking in adult germfree (gf) rats in that their peyer's patches (pp) contain high numbers of cells with sige (approximately 15% of total cells), one-half of which simultaneously express siga, whereas sige+ cells are absent from pp of conventional rats (less than 1%). gf rat pp also contain elevated numbers of siga+ cells and decreased numbers of sigm+ cells, with elevated numbers of sthy-1+ rt 7.1+ ig- t cells, and reduce ...19892789249
effective vancomycin therapy for corynebacterium pseudodiphtheriticum endocarditis. 19873423912
lower respiratory tract infections due to non-diphtheria corynebacteria in 8 patients with underlying lung diseases.non-diphtheria corynebacteria had been considered a commensal habitant of the human skin and mucous membrane. there are few reports of pulmonary infections due to corynebacterium pseudodiphtheriticum or other non-diphtheria corynebacteria occurring in immunocompetent patients. from 1978 to 1986, 8 patients with lower respiratory tract infections with corynebacterium sp. was observed. in 6 of 8 instances the causative microorganism was c. pseudodiphtheriticum. the above 8 patients had underlying ...19873441923
[clinical evaluations of flomoxef in respiratory tract infections].flomoxef (fmox, 6315-s), a new antibacterial drug, was administered to 9 cases with respiratory tract infections for a duration of 8 approximately 16 days at a daily dose of 2 g. diagnosis of these patients were bronchopneumonia 5 cases, chronic bronchitis 3 cases and acute bronchitis 1 case. from transtracheal aspiration several organisms were isolated; haemophilus influenzae was isolated in 3 cases, streptococcus pneumoniae in 3 cases, h. influenzae plus branhamella catarrhalis in 1 case, stre ...19873444019
endocarditis due to corynebacterium pseudodiphtheriticum. 19863456517
lung abscess involving corynebacterium pseudodiphtheriticum in a patient with aids-related complex. 19863467226
corynebacterium pseudodiphtheriticum associated with suppurative lymphadenitis. 19873569258
[a case of corynebacterium pseudodiphteriticum (hofmannii) endocarditis]. 19873692066
[subacute rhinosinusitis due to corynebacterium pseudodiphtheriticum]. 19863697872
carbenicillin-hydrolyzing beta-lactamase produced by corynebacterium pseudodiphtheriticum. 19853876322
corynebacterium pseudodiphtheriticum pneumonia in an immunologically intact host.corynebacterium pseudodiphtheriticum, a gram-positive bacillus commonly found in the human oropharynx, has been reported as a rare cause of infection in compromised hosts. we report herein a case of lower respiratory tract infection with corynebacterium pseudodiphtheriticum in a previously healthy 29-yr-old trauma victim. the organism was the predominant bacterial isolate from two endotracheal aspirates and a specific humoral response was demonstrated by enzyme-linked immunosorbent assay.19863956138
degradative versatility of corynebacterium pseudodiphtheriticum ncib 10803 which uses amides as carbon source. 19734578060
studies on the host phage systems of corynebacterium hofmanni species. 19724632613
[antigenic relationships between anti-corynebacterium hofmanni phages]. 19724681773
degradation and hydrolysis of amides by corynebacterium pseudodiphtheriticum ncib 10803. 19734765897
degradation and hydrolysis of esters by corynebacterium pseudodiphtheriticum ncib 10803. 19734765898
isolation and characterization of two antigens of corynebacterium hofmannii.banach, t. m. (university of manitoba, winnipeg, canada), and r. z. hawirko. isolation and characterization of two antigens of corynebacterium hofmannii. j. bacteriol. 92:1304-1310. 1966.-a serologically active substance, extracted from sonically treated cells of corynebacterium hofmannii with hot hcl, produced two precipitin lines by immunodiffusion tests with a hyperimmune homologous serum. extracts of other species failed to precipitate with the hofmannii antiserum. the active fraction was el ...19664958878
microstructure of colonies of rod-shaped bacteria.whole colonies of bacillus cereus, b. megaterium, b. mycoides cn2495, corynebacterium hofmanni nctc1938, escherichia coli, lactobacillus acidophilus ncib1899, nocardia graminis nctc4728, pseudomonas viscosa, and serratia marcescens were prepared for scanning electron microscopic examination by freeze-drying and metal-coating. the arrangement of individual cells within colonies could be seen. cells of bacillus colonies tended to be longer than in liquid culture and irregular in shape and to give ...19715001203
[cytoenzymological changes during phagocytosis. i. study on the dehydrogenases of the krebs cycle in peritoneal leukocytic exudate of guinea pigs during phagocytosis of corynebacterium hofmanni and of salmonella typhimurium, variants "s" and "r"]. 19645877133
pulmonary infection with corynebacterium hofmannii complicating systemic lupus erythematosus. 19836302181
[quantitative bacterial ecology of normal nasal mucosa].a quantitative research into the aerobic bacteria of human nasal cavities has been carried out; 183 healthy individuals observed, negative results 18 (9.83%). streptococcus, enterococcus, staphylococcus aureus, staphylococcus epidermidis, micrococcus, streptococcus pneumoniae, neisseria, were numerically determined and the incidence of each single species or genus exactly specified. among gram-negative bacteria, enterobacter, providencia, proteus, citrobacter freundii, haemophilus influenzae, kl ...19817034653
corynebacterium hofmannii infection after renal transplantation.a case of malakoplakia affecting the entire urinary tract is described. the patient had received a cadaveric renal transplant and had required particularly heavy immunosuppression because of recurrent rejection episodes. heavy hematuria developed, and this was followed by obstruction at the vesico-ureteric junction. despite adequate drainage via a nephrostomy, the graft ceased functioning, and was explanted. although appropriate antibiotics were given, the patient died. the organism responsible ...19827049476
discitis caused by corynebacterium pseudodiphtheriticum following ear, nose and throat surgery. 19957633809
corynebacterium pseudodiphtheriticum: a respiratory tract pathogen in adults.corynebacterium pseudodiphtheriticum has been reported to be an uncommon respiratory pathogen. we describe the clinical and microbiologic features of 17 patients from whose sputum c. pseudodiphtheriticum was isolated. patients were identified through a review of the reports from the clinical microbiology laboratory at york hospital, a community teaching hospital, from october 1990 through april 1993; 17 patients with respiratory infection caused by c. pseudodiphthriticum were identified. there w ...19957727667
corynebacterium pseudodiphtheriticum: a respiratory tract pathogen.from january 1986 through february 1993, there were 16 episodes of respiratory infection due to corynebacterium pseudodiphtheriticum in 13 patients. the ages of patients ranged from 24 to 77 years; the ratio of male to female patients was 3:1. one patient had three episodes of infection, and another patient had two. in one patient, who died of disseminated intravascular coagulation, the level of igg was low. one patient was receiving prednisolone when the infection occurred. in two cases a mixed ...19957727668
the superoxide dismutase gene, a target for detection and identification of mycobacteria by pcr.the superoxide dismutase gene has been identified as a target in screening for the presence of mycobacteria on the genus level and differentiating relevant mycobacterial species from one another by pcr. consensus primers deduced from known superoxide dismutase gene sequences allowed the amplification of dnas from a variety of bacteria, fungi, and protozoa. selected amplicons from actinomyces viscosus, corynebacterium diphtheriae, corynebacterium pseudodiphtheriticum, mycobacterium avium, m. fort ...19947852575
seven patients with respiratory infections due to corynebacterium pseudodiphtheriticum.seven cases of lower respiratory tract infection due to corynebacterium pseudodiphtheriticum are described. lower respiratory tract infections with c. pseudodiphtheriticum in immunocompetent patients are usually associated with pre-existing chronic pulmonary disease, and are sometimes associated with endotracheal intubation. antimicrobial susceptibility testing of these isolates showed uniform sensitivity to penicillin and variable results to erythromycin.19947991290
[corynebacterium pseudodiphtheriticum pneumonia in a patient diagnosed with hiv infection].corynebacterium pseudodiphteriticum is a diphteromorphic bacterium, previously described as pathogenic in very few cases. we present the case of a patient diagnosed of infection by the human immunodeficiency virus (hiv), who developed pneumonia probably caused by corynebacterium pseudodiphtheriticum and who had a good response to the initial empirical therapy with cephotaxime. we reviewed the literature on patients with diagnosis of hiv infection, acquired immunodeficiency syndrome (aids) and ai ...19938136430
numerical analysis of fatty and mycolic acid profiles of corynebacterium urealyticum and other related corynebacteria.the fatty and mycolic acid profiles of 52 strains of clinical origin belonging to corynebacterium urealyticum were subjected to numerical analysis along with those of representative members of corynebacterium ammoniagenes, corynebacterium bovis, corynebacterium glutamicum, corynebacterium jèikeium, corynebacterium minutissimum, corynebacterium pseudodiphtheriticum, corynebacterium pseudotuberculosis, corynebacterium xerosis, corynebacterium renale, corynebacterium cystitidis, "corynebacterium ul ...19938397966
studies on microbial aerobic flora of skin in leprosy patients.this study reports the isolation and identification of aerobic organisms from biopsies/slit-skin smears/scrapings from 129 leprosy patients and 50 healthy controls. these include 56 paucibacillary (pb) and 73 multibacillary (mb) cases. thirty-six isolates from the specimens from 21 patients and 15 healthy controls were grown. the non-mycobacterial isolates from clinically pb leprosy (tt/bt/i) patients were: (1) gram-positive cocci: staphylococcus aureus(1), staphylococcus albus(1); (b) gram-posi ...19958576610
suspected diphtheria in an uzbek national: isolation of corynebacterium pseudodiphtheriticum resulted in a false-positive presumptive diagnosis. 19968729231
respiratory infections: community-acquired pneumonia and newer microbes.respiratory infections, especially community-acquired forms of pneumonia (cap), are challenging for clinicians because (1) a causative microorganism can only be found in about 50% of cases; (2) initial therapy, therefore, must be based on a probable or most likely etiology in the context of the patient's overall medical condition; and (3) new microbes or those considered previously as normal flora or less virulent forms seem responsible for some cases. it is important to be acquainted with new c ...19968791258
species identities and antimicrobial susceptibilities of corynebacteria isolated from various clinical sources.over a 14-month period, 415 clinical isolates of coryneform gram-positive rods were recovered from various sources and identified to the species level according to recent identification schemes. corynebacterium urealyticum, corynebacterium striatum, corynebacterium amycolatum, and corynebacterium jeikeium predominated, accounting for 63% of all isolates. corynebacterium accolens, corynebacterium striatum, corynebacterium argentoratense, corynebacterium propinquum and corynebacterium pseudodiphth ...19968894575
isolation and identification of styrene-degrading corynebacterium strains, and their styrene metabolism.by supplying styrene in the gas phase as the sole carbon and energy source, styrene-degrading aerobic microorganisms were readily isolated from soil samples. they were identified as corynebacterium pseudodiphtheriticum and similar species, or pseudomonas sp. growth experiments on some aromatic compounds, resting-cell reactions with them, and the measurement of degrading enzyme activities suggest that corynebacterium sp. ac-5 and st-5 strains metabolize styrene through styrene oxidation into styr ...19968987859
[pneumonia by corynebacterium pseudodiphthericum]. 19969053016
[effect of piperacillin/tazobactam on the anti-infection resistance in patients with infections in the peritoneal cavity].the effect of the monotherapy with piperacillin/tazobactam (p/t) or tazocin on microflora of the mucous membranes of the nose and pharynx of 33 patients and the contents of the large intestine of 21 patients as well as on the immunological aspects (cellular and humoral factors) of the antiinfectious resistance systems (airs) in patients with abdominal cavity infection (aci) was studied. before the treatment serious impairment of the airs in all the patients was observed. the p/t monotherapy in a ...19979124993
exudative pharyngitis possibly due to corynebacterium pseudodiphtheriticum, a new challenge in the differential diagnosis of diphtheria.corynebacterium pseudodiphtheriticum has rarely been reported to cause disease in humans, despite its common presence in the flora of the upper respiratory tract. we report here a case of exudative pharyngitis with pseudomembrane possibly caused by c. pseudodiphtheriticum in a 4-year-old girl. the case initially triggered clinical and laboratory suspicion of diphtheria. because c. pseudodiphtheriticum can be easily confused with corynebacterium diphtheriae in gram stain, clarification of its rol ...19979126447
opportunistic lung infection with corynebacterium pseudodiphtheriticum after lung and heart transplantation.corynebacterium pseudodiphtheriticum is usually regarded as a harmless commensal of the skin and mucous membranes. we describe two cases of bronchiolitis and bronchitis after lung and heart transplantation, respectively, in which this organism was strongly implicated as the pathogen.19979137282
exudative pharyngitis possibly due to corynebacterium pseudodiphtheriticum. 19979204312
[corynebacterium pseudodiphtheriticum: a new respiratory pathogen? presentation of one case of acute suppurative tracheobronchitis]. 19989542312
[utilization of staphylococcus siderophores produced by corynebacterium and coryneform bacteria].the ability of iron utilizing by means of siderophores produced by donor strains-coryne-bacterium and coryneform organisms (8 strains) by 24 staphylococcal strains was investigated. all the donor strains synthesized catecholate class siderophores and two strains also hydroxamate class. the majority of staphylococcal strain could utilize these siderophores. most of strains utilized siderophores from corynebacterium pseudodiphtheriticum and corynebacterium aquaticum as well as chelators from plant ...19979554144
in vitro susceptibilities of aerobic and facultative non-spore-forming gram-positive bacilli to hmr 3647 (ru 66647) and 14 other antimicrobials.the comparative in vitro activity of the ketolide hmr 3647 (ru 66647) and those of structurally related macrolide-lincosamide-streptogramin compounds (erythromycin, roxithromycin, azithromycin, clarithromycin, josamycin, lincomycin, pristinamycin, and quinupristin-dalfopristin) as well as those of benzylpenicillin, doxycycline, vancomycin, teicoplanin, levofloxacin, and rifapentine against 247 aerobic and facultative non-spore-forming gram-positive bacilli were determined by an agar dilution met ...19989593121
coryneform bacteria in throat cultures of healthy individuals.throat swabs from 113 healthy individuals from hamburg, germany, and zurich, switzerland, were investigated for coryneform bacteria with nonselective and selective media. ninety specimens contained 123 strains. surprisingly, 76% of them were strains of corynebacterium durum (47%) and rothia dentocariosa (29%). only two were strains of corynebacterium pseudodiphtheriticum, and none were strains of c. striatum, c. amycolatum, or c. diphtheriae.19989650969
corynebacterium pseudodiphtheriticum: an easily missed respiratory pathogen in hiv-infected patients.despite being a well-known respiratory pathogen for immunocompromised patients, corynebacterium pseudodiphtheriticum has uncommonly been reported to occur in persons with infection attributable to hiv virus. we report three cases of respiratory tract infection attributable to c. pseudodiphtheriticum in hiv-infected patients and review the four previous cases from the medical literature. all of them were male with a median cd4 lymphocyte count of 110 cells/mm3 (range, 18-198/mm3); five of the sev ...199910212746
corynebacterium pseudodiphtheriticum pneumonia in an immunocompetent patient.corynebacterium pseudodiphtheriticum is a coryneform and diphtheromorphic bacteria rarely found as a cause of pneumonia in immunocompetent hosts. a case of an immunocompetent patient with c. pseudodiphtheriticum pneumonia is presented. this infection responded well to initial empirical treatment with cefotaxime. very few cases of pneumonia associated with c. pseudodiphtheriticum have been described in the medical literature, this organism mainly being found in immunocompromised hosts. we report ...199910546474
corynebacterium pseudodiphtheriticum--a skin pathogen. 199910589918
a case of corynebacterium pseudodiphtheriticum nosocomial pneumonia. 199910610204
corynebacterium pseudodiphtheriticum keratitis and conjunctivitis: a case report.a case of keratitis and conjunctivitis in an 86-year-old man caused by corynebacterium pseudodiphtheriticum is reported. corynebacteria are uncommon causes of ocular surface infections. however, the presence of corneal and conjunctival epithelial defects in an immunocompromised patient can result in severe infection by a commensal organism such as c. pseudodiphtheriticum. the significance of a positive culture in these settings should not be overlooked.200011345349
[pneumonia caused by corynebacterium pseudodiphteriticum, an entity worth knowing].respiratory infections are challenging for clinicians and new microbes or those considered previously as normal flora or less virulent forms seen responsible for some cases. thus, the case reported here is a nosocomial pneumonia caused by corynebacterium pseudodiphteriticum in a man suffering chronic obstructive pulmonary disease and resolved with cefotaxime. this microorganism is part of the oropharingeal bacterial flora and is therefore associated mainly with respiratory disease an less common ...200212420632
in vitro activities of daptomycin, vancomycin, quinupristin- dalfopristin, linezolid, and five other antimicrobials against 307 gram-positive anaerobic and 31 corynebacterium clinical isolates.the activities of daptomycin, a cyclic lipopeptide, and eight other agents were determined against 338 strains of gram-positive anaerobic bacteria and corynebacteria by the nccls reference agar dilution method with supplemented brucella agar for the anaerobes and mueller-hinton agar for the corynebacteria. the daptomycin mics determined on ca(2+)-supplemented (50 mg/liter) brucella agar plates were one- to fourfold lower than those determined in unsupplemented media. daptomycin was highly active ...200312499210
[endocarditis due to corynebacterium pseudodiphtheriticum]. 200312586039
activities of abt-773 against listeria monocytogenes and coryneform bacteria of clinical interest.the in vitro activities of abt-773 were evaluated against 15 listeria monocytogenes strains and 196 coryneform bacteria isolated from clinical samples. one hundred percent of the l. monocytogenes strains were inhibited by </=0.015 micro g of abt-773/ml. mics of abt-773 ( micro g/ml) at which 50% of the isolates tested were inhibited (mic(50)s) and mic(90)s for other organisms were 0.125 and 0.5 (corynebacterium amycolatum), 1 and >32 (corynebacterium jeikeium), 0.03 and >32 (corynebacterium minu ...200312654678
[microflora of the nasal mucosa in allergic perennial and infectious rhinitis].the microbiological study of 69 patients with allergic annual rhinitis (aar) and infectious rhinitis (ir) was carried out. in aar the isolated representatives of 15 genera and 40 species were distributed in 2 to 7 component; in ir the isolated representatives of 16 genera and 25 species were grouped in 2 to 4-component associations. in aar staphylococcus aureus was found to belong to the main species and in ir, s. aureus and s. epidermidis, while the number of species regarded as occasional in a ...200312886636
[differentiation of corynebacterium diphtheriae from hofman-wellenhof's corynebacterium pseudodiphthericum by the detection of gas in a dextrose-urea tube]. 195313091064
mitosis-like figures in corynebacterium pseudodiphtheriticum. 195413221759
[variability of corynebacterium pseudodiphtheriticum in organisms of experimental animals]. 195513257812
identification of species of brucella using fourier transform infrared spectroscopy.fourier transform infrared spectroscopy (ftir) is a technique that has been used over the years in chemical analysis for the identification of substances and is one that may be applied to the characterisation of microorganisms. the marked tendency of brucella towards variation in the smooth rough phase, together with the laboriousness and risk involved in the methods used in their identification, make their classification difficult. we studied the type strains of the different species and biovar ...200314500003
[three adult cases with corynebacterium propinquum respiratory infections in a community hospital].corynebacterium propinquum, which is included in corynebacterium group anf-3, exists as a commensal in the oral flora. this organism has not yet been fully recognized as a respiratory pathogen. we previously reported that the first case with respiratory infection caused by c. propinquum. on the other hand, corynebacterium pseudodiphtheriticum is recognized as a causative organism in respiratory infections. recently we experienced two cases with c. propinquum respiratory infections in our hospita ...200415103912
the role of opportunistic species of corynebacterium pseudodiphtheriticum in the pathogenesis of cap (community acquired pneumonia).the analysis of eight cases of cap (community acquired pneumonia) was performed. the clinical samples of sputum were obtained from patients at which c. pseudodiphtheriticum strains were isolated in the quantity indicating the etiologic agent of infection. in two patients, k. pneumoniae and s. aureus were isolated simultaneously. they were considered as coexisting in the infection. c. pseudodiphtheriticum strains were highly susceptible to antibiotics. they were resistant to erythromycin (87.5%), ...200315314974
microbial etiologies in community acquired pneumonia (cap).the objective of the study was determination of bacterial etiologic factors, including antibiotic atypical pathogens, of community acquired pneumonia (cap) in adults and of sensitivity of isolated strains. the examined group comprised 50 patients with clinical and x-ray image of pneumonia. patients' expectoration sputum was analyzed. amongst all isolated bacteria, the most frequent were staphylococcus aureus - 17.9%, haemophilus parainfluenzae - 12.5% and h. influenzae - 8.9%. identification of ...200315315033
[subacute bacterial endocarditis, probably caused by corynebacterium pseudodiphthericum (hofmann's bacillus)]. 195015439426
demonstration by pcr and dna sequencing of corynebacterium pseudodiphtheriticum as a cause of joint infection and isolation of the same organism from a surface swab specimen from the patient.a case of infectious arthritis following arthroscopy is described. real-time pcr, using universal bacterial primers targeting the 16s rrna gene, and subsequent dna sequencing of the pcr product demonstrated the presence of dna from corynebacterium pseudodiphtheriticum in the synovial fluid from the affected knee. culture from a surface swab from the site of purulent discharge from the knee was initially reported as growing normal skin microbiota. knowing the result of the dna analysis, the speci ...200515947436
species identification of corynebacteria by cellular fatty acid analysis.we evaluated the usefulness of cellular fatty acid analysis for the identification of corynebacteria. therefore, 219 well-characterized strains belonging to 21 corynebacterium species were analyzed with the sherlock system of midi (newark, de). most corynebacterium species have a qualitative different fatty acid profile. corynebacterium coyleae (subgroup 1), corynebacterium riegelii, corynebacterium simulans, and corynebacterium imitans differ only quantitatively. corynebacterium afermentans afe ...200616423489
[pneumonia by corynebacterium pseudodiphteriticum: an infection to consider].corynebacterium pseudodiphteriticum has been considered a very infrequent respiratory pathogen. we report three cases of pneumonia due to c. pseudodiphteriticum, describing their clinical and microbiological features. there were two patients with pre-existing chronic respiratory disease, one of their with steroidal therapy, and other associated with endotracheal intubation. the diagnostic was made by gram stain and quantitative cultures from respiratory tract specimens. all patients were cured a ...200616737433
[evaluation of api coryne system, version 2.0, for diphteroid gram-positive rods identification with clinical relevance].the ability of the api coryne system, version 2.0, to identify 178 strains of gram-positive rods was evaluated. seventy eight isolates belonged to genus corynebacterium and one hundred to related genera, all strains were isolated from clinical samples at the laboratory of bacteriology, hospital de clínicas josé de san martin (uba) between 1995 and 2004. the isolates were identified according to von graevenitz and funke's scheme. one hundred and sixty two out of 178 strains (91%) were correctly i ...200617370571
expression of a functional single-chain antibody via corynebacterium pseudodiphtheriticum.antibody-based therapeutics are effective against conditions ranging from acute infections to malignancy. they may prove crucial in combating bioterrorism and responding to drug-resistant and emerging pathogens. at present the cost of producing therapeutic monoclonal antibodies is between $1,000 to $6,000 per gram. the need to administer antibodies parenterally at frequent intervals further drives the cost of this treatment. here we present an antibody delivery system, termed paratransgenesis, w ...200818322717
cutaneous infection caused by corynebacterium pseudodiphtheriticum: a microbiological report.we report here a rare case of cutaneous infection due to corynebacterium pseudodiphtheriticum. the patient presented to the clinical laboratory with a skin ulcer on his left leg. gram-stained preparation of the purulent secretion revealed the presence of numerous rod-shaped gram-positive organisms in the absence of any other species. the organism was grown in pure culture on sheep blood agar and was further identified as c. pseudodiphtheriticum using a commercial identification system (api-coryn ...200818327488
corynebacterium pseudodiphtheriticum isolated from relevant clinical sites of infection: a human pathogen overlooked in emerging countries.to examine the occurrence of and to determine the antimicrobial susceptibility of corynebacterium pseudodiphtheriticum among patients with bacterial infections at a teaching hospital.200919228291
the reactions between bacteria and animal tissues under conditions of artificial cultivation.this report gives an outline of the results of observations on over 1,100 tissue cultures made during the fall, winter, and spring of 1913 to 1914. the work has been resumed in the fall of 1914 and will be continued along the same and allied lines, confirming the above results with other strains of the same organisms and with other bacteria and bacterial products. tests should be made with tissue and plasma from other animals, and the known pathogenicity of the organism for the animal and tissue ...191519867854
microbiological and host features associated with corynebacteriosis in cancer patients: a five-year study.during a five-year period, 932 clinical isolates from cancer patients treated in a brazilian reference centre were identified as corynebacteria; 86% of the cultures came from patients who had been clinically and microbiologically classified as infected and 77.1% of these patients had been hospitalised (71.1% from surgical wards). the adult solid tumour was the most common underlying malignant disease (66.7%). the univariate and multivariate analyses showed that hospitalised patients had a six-fo ...200919876565
[two cases of corynebacterium pseudodiphtheriticum respiratory tract infection].corynebacterium pseudodiphtheriticum, one cause of respiratory tract infection, is rarely considered as a pathogen because it is among normal bacterial flora colonizing the oral cavity. we report two cases of c. pseudodiphtheriticum causing respiratory tract infection--an exacerbation of chronic obstructive pulmonary disease and pneumonia--, both in the presence of underlying respiratory disease. both required antibiotics after first-line chemotherapy failed. isolates were susceptible to beta-la ...201020170017
macrolide, lincosamide, and streptogramin b-constitutive-type resistance in corynebacterium pseudodiphtheriticum isolated from upper respiratory tract specimens.corynebacterium pseudodiphtheriticum is commonly found in normal upper respiratory tract flora in humans. in certain conditions it can cause the opportunistic infections, especially in immunocompromised patients. in certain strains of corynebacterium sp., the macrolide, lincosamide, and streptogramin b (mlsb) resistance mechanism related to the presence of the erm(x) gene was discovered; hence, the need appeared for further investigation to confirm the existence of this gene among c. pseudodipht ...201020438346
outbreak of corynebacterium pseudodiphtheriticum infection in cystic fibrosis patients, france.an increasing body of evidence indicates that nondiphtheria corynebacteria may be responsible for respiratory tract infections. we report an outbreak of corynebacterium pseudodiphtheriticum infection in children with cystic fibrosis (cf). to identify 18 c. pseudodiphtheriticum strains isolated from 13 french children with cf, we used molecular methods (partial rpob gene sequencing) and matrix-assisted laser desorption ionization time-of-flight (maldi-tof) mass spectrometry. clinical symptoms wer ...201020678316
[corynebacterium pseudodiphtheriticum causing severe pneumonia in secondary immunoglobulin deficiency].corynebacterium pseudodiphtheriticum is of increasing importance because of the rising number of immunocompromised patients. pneumonia, but also endocarditis, urinary tract infections or keratitis can be caused by this bacteria in case of immunosuppression. taking corynebacterium pseudodiphtheriticum into consideration as causitive agent provides for a fast onset of targeted antibiotic therapy.201122109586
non-diphtheriae corynebacterium species: an emerging respiratory pathogen.the purpose of the study was to describe the microbiological and clinical features of ten cases of lower respiratory tract infection due to corynebacterium striatum, corynebacterium propinquum and corynebacterium pseudodiphtheriticum. respiratory samples were recovered from hospitalised patients who were diagnosed of pneumonia and exacerbations of chronic respiratory infections. the samples were gram-stained and seeded on conventional bacterial growing media. bacteria were identified by matrix-a ...201223271676
development of upper respiratory tract microbiota in infancy is affected by mode of delivery.birth by caesarian section is associated with short- and long-term respiratory morbidity. we hypothesized that mode of delivery affects the development of the respiratory microbiota, thereby altering its capacity to provide colonization resistance and consecutive pathobiont overgrowth and infections. therefore, we longitudinally studied the impact of mode of delivery on the nasopharyngeal microbiota development from birth until six months of age in a healthy, unselected birth cohort of 102 child ...201627333043
diphtheroids-important nosocomial pathogens.diphtheroids are defined as aerobic, non-sporulating, pleomorphic gram-positive bacilli which are more uniformly stained than corynebacterium diphtheriae, lack the metachromatic granules and are arranged in a palisade manner. they are usually commensals of the skin and mucous membranes. they differ from c.diphtheriae in biochemical rea-ctions as well as in toxin production. since, they are usually found as commensals on the skin, they are often considered as mere contaminants when isolated from ...201628208859
candida albicans mucin msb2 is a broad-range protectant against antimicrobial peptides.the human fungal pathogen candida albicans releases a large glycofragment of the msb2 surface protein (msb2*) into the growth environment, which protects against the action of human antimicrobial peptides (amps) ll-37 and histatin-5. quantitation of msb2*/ll-37 interactions by microscale thermophoresis revealed high-affinity binding (dissociation constant [kd] = 73 nm), which was lost or greatly diminished by lack of o-glycosylation or by msb2* denaturation. msb2* also interacted with human α- a ...201323733470
[macrophage apoptosis as a mechanism of pathogenic effect of diphtheria infectious agent].study of the apoptogenic effect of corynebacterium diphtheriae toxigenic strains on mice peritoneal macrophages in vitro.201223163039
emendation of the description of the species corynebacterium propinquum to include strains which produce urease.corynebacterium propinquum is a gram-positive rod occasionally recovered from clinical infections which, according to 16s rrna gene sequencing, is most closely related (>99% sequence similarity) to corynebacterium pseudodiphtheriticum. the two species are very similar biochemically, commonly differentiated by a single test, the detection of urease, where strains of c. propinquum are described as being urease-non-producing and strains of c. pseudodiphtheriticum are described as urease-producing. ...201323104363
corynebacterium pseudodiphtheriticum septic arthritis secondary to intra-articular injection--a case report and literature review.this is believed to be the first report of a case of septic arthritis, secondary to intra-articular injection, caused by corynebacterium pseudodiphtheriticum - a skin commensal micro-organism. review of the literature highlights the rarity of this pathogen in osteoarticular infections and a potential for delayed diagnosis and inadequate treatment due to subtle initial presentation.201222361458
aggregative adherent strains of corynebacterium pseudodiphtheriticum enter and survive within hep-2 epithelial cells.corynebacterium pseudodiphtheriticum is a well-known human pathogen that mainly causes respiratory disease and is associated with high mortality in compromised hosts. little is known about the virulence factors and pathogenesis of c. pseudodiphtheriticum. in this study, cultured human epithelial (hep-2) cells were used to analyse the adherence pattern, internalisation and intracellular survival of the atcc 10700 type strain and two additional clinical isolates. these microorganisms exhibited an ...201222666859
bronchopneumonia caused by corynebacterium pseudodiphtheriticum. 201323955623
corynebacterium endocarditis of a percutaneously placed transcatheter pulmonary valve.we report a case of endocarditis of a transcatheter pulmonary valve-in-valve in a 14-year-old boy with tetralogy of fallot. he presented with recurrent low-grade fevers, lethargy, and anorexia. multiple blood cultures grew a gram-positive rod, corynebacterium pseudodiphtheriticum. he was taken to the operating room for removal of the vegetative endocarditis and pulmonary valve replacement.201424103793
draft genome sequence of corynebacterium pseudodiphtheriticum strain 090104 "sokolov".this report describes the first draft genome sequence of a corynebacterium pseudodiphtheriticum strain. the information on the genome organization and putative gene products will assist in better understanding of the molecular mechanisms involved in the beneficial probiotic effects of this bacterium.201324201200
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