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morphology, density and distribution of tyrosine hydroxylase immunoreactive cells in the retina in the gerbil meriones shawi. relationships with horizontal cells.dopamine neurons have been demonstrated with the use of tyrosine hydroxylase (th)-immunohistochemistry in the retina of meriones shawi, a wild species of pigmented sand rat, in order to compare their morphology, density, and distribution with those in albino laboratory rat. the morphology and density of th-immunoreactive cells were quite comparable in the two species: the dopamine cell population was composed of amacrine cells, displaced amacrine cells, and interplexiform cells, these latter bei ...19911685740
anti-leishmanial antibodies during natural infection of psammomys obesus and meriones shawi (rodentia, gerbillinae) by leishmania major.sera from 77 rodents (psammomys obesus: 64; meriones (m.) shawi: 10; m. libycus: 3) trapped in a focus of zoonotic cutaneous leishmaniasis (zcl) (leishmania (l.) major) were examined for the presence of anti-leishmanial antibodies by the indirect fluorscence antibody technique (ifat) (l. major antigens) using homologous antiglobulins and/or anti-rattus conjugates. sera from 21 animals were positive with titres that ranged from 1: 20 up to 1: 640. the investigation revealed that a good correlatio ...19892658879
[isolation of leishmania major yakimoff and shokhor, 1914 (kinetoplastida-trypanosomatidae) in meriones shawi-shawi (duvernoy, 1842) (rodentia-gerbillidae) in tunisia].leishmania major, agent of zoonotic cutaneous leishmaniasis, has been isolated from the rodent meriones shawi shawi in central tunisia. as a result, the north saharan arid mediterranean area can be considered as epidemiologically homogeneous.19863729234
[meriones shawi (duvernoy, 1842) [rodentia, gerbillidae] a reservoir of leishmania major, yakimoff and schokhor, 1914 [kinetoplastida, trypanosomatidae] in south morocco (author's transl)].for the first time a report is made of meriones shawi (duvernoy, 1842) infected by leishmania major yakimoff and shokhor, 1914. the parasite was observed in two of 28 meriones captured in the immediate vicinity of the tata administrative center (south morocco). m. shawi, because it is sub-commercial with man and abundant, is very likely one of the reservoirs of human cutaneous leishmaniasis in this area.19826807510
experimental efficiency of phlebotomus papatasi in maintaining development of four species of leishmania.experimental infections were carried out to evaluate the capability of 3 species of phlebotomus to acquire and allow development of 4 species of leishmania. the sand-flies were allowed to feed on infective blood by a membrane feeding technique and infected vertebrate hosts. the species of phlebotomus experimented with were p. papatasi (egyptian and indian strains), p. dubosqi (sinegal strain), and p. perniciosus (french strain). the species of leishmania used were l. tropica (afganistanian strai ...19921578171
histopathological observations in new and classic models of experimental schistosoma haematobium infections.the authors present marsh rat holochilus brasiliensis, jirds meriones shawi and m. unguiculatus as new models of schistosoma haematobium infection. histological findings were compared with those of classic models mouse mus and hamster mesocricetus. in new models, embryonated eggs were seen in the stool from 90 days post infestation (dpi) and active disease developed from 117 to 175 dpi. seven out of 10 rodents presented granulomatous and/or chronic cystitis, fibrosis, polyps and urothelial chang ...19968673838
[organization of the primary visual system of 2 rodents arvicola terrestris and meriones shawi].radio-autography and fink-heimer technique were performed in two rodents, the nocturnal meriones shawi (cricetidae, gerbillidae) and the subterranean arvicola terrestris (arvicolidae) in order to investigate the organization of the primary visual system. in general the whole visual system is poorly developed in arvicola. in two species, contralaterally, visual inputs project to nuclei geniculatus dorsalis and ventralis, pretectum and colliculus anterior (at the level of stratum opticum and the s ...19836345658
historadioautographic localisation of oxytocin and vasopressin binding sites in the central nervous system of the merione (meriones shawi).the distribution of vasopressin and oxytocin binding sites in the central nervous system of the merione (meriones shawi), a rodent adapted to desert life, was studied by means of conventional film radioautography at macroscopic scale and historadioautography at cellular level using radioiodinated ligands highly selective for either oxytocin or type v1 a vasopressin receptors. both types of binding sites exhibited the same selectivity for endogenous peptides as in the rat. distribution of oxytoci ...199910230706
photoperiod, but not a high-fat diet, alters body fat in shaw's jird.many animal species living in temperate zones show annual body fat cycles. in an apparent regulation of total body fat, species showing naturally occurring decreases in adiposity in the fall (e.g., meadow voles and siberian hamsters) are resistant to high-fat diet (hfd)-induced obesity in short, "winter-like" days (sds), and in long, "summer-like" days (lds) at their peak adiposity. sd-exposed shaw's jirds (meriones shawi) show sd-induced decreases in body fat; therefore, we predicted they also ...199910627066
hypolipidemic and hypocholesterolemic effect of argan oil (argania spinosa l.) in meriones shawi rats.the potential health benefits of various dietary oils in relation to cardiovascular disease and cancer are recently receiving considerable attention. the main proposal of this study is to investigate the effect of dietary argan oil, obtained from seeds of argania spinosa l. (sapotaceae) endemic from morocco, on serum lipids composition. hyperlipidemia was induced by high calorie and cholesterol (hcc) diet administration in 16 rats (meriones shawi, a rodent of the gerbillideae family). eight rats ...200314522427
[experimental evidence of an antihypertensive and hypocholesterolemic effect of oil of argan, argania sideroxylon].the chronic ingestion of 5 ml/kg/d of argan oil by spontaneously hypertensive rats restores normal blood pressure and induces hypocholesterolaemia. in order to confirm these results meriones shawi, a rodent of the gerbillideae family, was tested as a second animal model. meriones submitted to a hypercaloric diet and physical inactivity became fat, and exhibited hypertension, dyslipidaemia and hyperinsulinaemia. when treated for two months with the same dosage regimen, decreases in glycaemia, tot ...200010967715
control of reproductive and energetic status by environmental cues in a desert rodent, shaw's jird.the photoperiod is the controller of reproductive cycles in temperate climates for most mammalian species. several nonphotoperiodic cues appear to control reproductive status at lower latitudes. we tested the roles of the photoperiod or water availability on the reproductive status of the desert-dwelling shaw's jird (meriones shawi) trapped from a moderately temperate climate (approximately 30 degrees n in egypt). males and females were transported to the laboratory and, in experiment 1, were ho ...199910386911
[human leishmaniases in morocco: a nosogeographical diversity.]leishmaniases in morocco are endemic diseases. three forms of leishmaniasis are reported, visceral leishmaniasis, cutaneous leishmaniasis caused by leishmania tropica and cutaneous lesions due to leishmania major. leishmania infantum, a common parasite inducing visceral leishmaniasis, was observed thereafter in cutaneous lesions. the first case of cutaneous leishmaniasis due to l. tropica was isolated since 1987. but, this parasite was shown to be more polymorphic with almost 8 zymodemes. howeve ...200919942371
[action of cortisone and pilocarpine on the development of the salivary virus in the field-mouse (apodemus sylvaticus), the gerbil (meriones shawi) and the jerboa (dipodillus campestris)]. 196414190402
[on the virulence of plasmodium berghei, hemosporidia of a rodent of central africa to the north african rodent meriones shawi]. 195014800475
[not available]. 194718896585
leishmania major infection among psammomys obesus and meriones shawi: reservoirs of zoonotic cutaneous leishmaniasis in sidi bouzid(central tunisia).a study was undertaken between november 2008 and march 2010, in the focus of cutaneous leishmaniasis of central tunisia, to evaluate the role of psammomys obesus (n=472) and meriones shawi (n=167) as reservoir hosts for leishmania major infection. prevalence of l. major infection was 7% versus 5% for culture (p=not signifiant [ns]), 19% versus 16% for direct examination of smears (p=ns), and 20% versus 33% (p=ns) for indirect fluorescent antibody test among p. obesus and m. shawi, respectively. ...201121919726
epidemiology of tick-borne borreliosis in morocco.the presence in morocco of argasid ticks of the ornithodoros erraticus complex, the vector of tick-borne relapsing fever (tbrf) in north africa, has been known since 1919, but the disease is rarely diagnosed and few epidemiological data are available.201223029574
coarse-resolution ecology of etiological agent, vector, and reservoirs of zoonotic cutaneous leishmaniasis in libya.cutaneous leishmaniasis ranks among the tropical diseases least known and most neglected in libya. world health organization reports recognized associations of phlebotomus papatasi, psammomys obesus, and meriones spp., with transmission of zoonotic cutaneous leishmaniasis (zcl; caused by leishmania major) across libya. here, we map risk of zcl infection based on occurrence records of l. major, p. papatasi, and four potential animal reservoirs (meriones libycus, meriones shawi, psammomys obesus, ...201626863317
hypoglycemic and hypolipidemic effects of an aqueous extract of chamaerops humilis leaves in obese, hyperglycemic and hyperlipidemic meriones shawi rats.ethnopharmacological relevance: an aqueous concoction made from the leaves of chamaerops humilis (l.) (dwarf fan palm), is used in the moroccan traditional medicine for the treatment of diabetes, as well as a number of other diseases. the aim of the study was to experimentally validate the use of c. humilis in the folk treatment of diabetes as well as to determine if the aqueous leaf extract of this plant has hypolipidemic properties in an animal model of obesity, hyperglycemia and hyperlipidemi ...201020363702
hypoglycemic and hypolipidemic effects of coriandrum sativum l. in meriones shawi rats.the use of an aqueous extract of coriander (coriandrum sativum l.; apiaceae, umbelliferae) seeds (cs-extract) in moroccan traditional treatment of diabetes remains to be experimentally validated.201121718774
electrophoretic pattern of haemoglobins in two gerbil species: meriones shawi and meriones unquiculatus. 20134435262
control of cutaneous leishmaniasis caused by leishmania major in south-eastern morocco.the incidence of cutaneous leishmaniasis (cl) caused by leishmania major has increased in morocco over the last decade, prompting the ministry of health to take intersectoral response measures including vector and reservoir control. the aim of this article was to describe the cl outbreak response measures taken in the province of errachidia, where the reservoir of l. major, a sand rat (meriones shawi), was targeted using strychnine-poisoned wheat baits from 2010 to 2012.201525975767
laboratory and field evaluation of rodent bait treated with fipronil for feed through and systemic control of phlebotomus papatasi.the sand fly phlebotomus papatasi is the main vector of leishmania major, etiologic agent of zoonotic cutaneous leishmaniasis (zcl), which is endemic in north africa, the middle east, and asia. in north africa, meriones shawi is one of the two main reservoir hosts of l. major. p. papatasi populations are maintained in borrowing rodents such as m. shawi. three fipronil-treated rodent baits were evaluated for systemic and feed through insecticidal activity against p. papatasi feeding on m. shawi. ...201424681222
[laboratory and field evaluation of an imidacloprid treated rodent oral bait for a systemic control of phlebotomus papatasi scopoli, 1786 (dipetra: psychodidae)].the objective of this study was to evaluate the systemic insecticidal activity of an imidacloprid-treated rodent oral bait, against phlebotomus papatasi scopoli, 1786 vector of leishmania major yakimoff & schokhor, 1914 (kinetoplastida: trypanosomatidae), etiologic agent of zoonotic cutaneous leishmaniasis (zcl). shaw's gerbil meriones shawi duvernoy, 1842 (rodentia, gerbillidae) were treated with imidacloprid-treated bait (0.05%). in the laboratory, effects on adult and larval of phlebotomus pa ...201323299949
molecular detection of leishmania infantum and leishmania tropica in rodent species from endemic cutaneous leishmaniasis areas in morocco.leishmaniasis remains a major public health problem in african nations, including morocco, where little is known about the vertebrate reservoirs involved in the causal parasites' transmission cycles. the present study investigates the role of rodent species as potential reservoirs of leishmania spp. in central morocco, where both l. tropica and l. infantum have been reported.201728969710
[leishmania major yakimoff et schokhor, 1914 (kinetoplastida: trypanosomatidae) in meriones shawi duvernoy, 1842 (rodentia: gerbillidae): persistence of the infection in meriones and its infectivity for the sand fly vector (phlebotomus) papatasi scopoli, 1786 (diptera: psychodidae)].the ability of the sand fly phlebotomus papatasi to transmit leishmania major, the etiologic agent of zoonotic cutaneous leishmaniasis, to meriones shawi, the natural reservoir host of this parasite, was studied under laboratory conditions. sand flies became infected with l. major after feeding on a lesion of needle-inoculated m. shawi. moreover, p. papatasi, previously infected with l. major, transmitted the parasite to m. shawi by bite during a second bloodmeal. two months after the blood-meal ...201223055379
meggittina numida n. sp. (cyclophyllidea: catenotaeniidae), a parasite of the shaw's jird meriones shawi (duvernoy) (rodentia: gerbillinae) in tunisia.meggittina numida n. sp. (cyclophyllidea: catenotaeniidae: skrjabinotaeniinae) is described from the small intestine of the shaw's jird meriones shawi (duvernoy) (rodentia, muridae, gerbillinae) trapped in central tunisia. the new species can be distinguished from the four other members of meggittina lynsdale, 1953 by the high number of proglottids (8-25 vs max. 6) and by the elongated strobila (8.2-60 mm in length vs max. 5.6 mm). m numida n. sp. further differs from m. cricetomydis (hockley, 1 ...201424832187
[importance of shaw's jird meriones shawii within the trophic components of the barn owl tyto alba in steppic areas of algeria].the study of the diet of the barn owl in two steppic regions (m'sila and djelfa) located in the algerian highlands is based on the analysis of the pellets of rejections collected in six stations. the analysis of 706 pellets resulting from the various stations made it possible to count 1380 individuals, represented by seven classes, 12 orders, 32 families, and 76 species of preys. the mammals are consumed with variable abundance rates between 59.1 % and 90.0 % whose predominance is assigned to th ...201424961561
hybridization in the rodent genus meriones. i. breeding and cytological analyses of meriones shawi (female) crossed meriones libycus (male) hybrids. 19695770277
study of retinal neurodegeneration and maculopathy in diabetic meriones shawi: a particular animal model with human-like macula.the purpose of this work was to evaluate a potentially useful animal model, meriones shawi (m.sh)-developing metabolic x syndrome, diabetes and possessing a visual streak similar to human macula-in the study of diabetic retinopathy and diabetic macular edema (dme). type 2 diabetes (t2d) was induced by high fat diet administration in m.sh. body weights, blood glucose levels were monitored throughout the study. diabetic retinal histopathology was evaluated 3 and 7 months after diabetes induction. ...201728542922
study of retinal alterations in a high fat diet-induced type ii diabetes rodent: meriones shawi.diabetic retinopathy is a common complication of type 2 diabetes and the leading cause of blindness in adults of working age. the aim of this work was to study the repercussions of high fat diet (hfd) induced diabetes on the retina of meriones shawi (m.sh). two groups of six m.sh each was studied. group i was a normal control, fed with standard laboratory granules. in group ii, rodents received a hfd of enriched laboratory granules, for a period of 3 months. body weight and plasma glucose were d ...201727265809
alteration of dopaminergic innervation and voluntary movements after long period of thirst in a semi-desert rodent, meriones shawi: behavioral and immunohistochemical studies.dehydration is a powerful stimulus causing disequilibrium in homeostasis of water and electrolytes resulting from depletion in total body water. most studies have focused on domestic and laboratory animals; however, the study of desert animals allows improved understanding about water balance and resistance to dehydration and associated behavioral changes, including those related to voluntary movements. meriones shawi (shaw's jird) is a desert rodent characterized by its resistance to long perio ...201222847013
effects of dietary cadmium exposure on osmoregulation and urine concentration mechanisms of the semi-desert rodent meriones shawi.contamination by cadmium in the environment is of great concern because of its toxicity and threats to human and animal health. the current study was conducted to investigate the effects of a cadmium contaminated diet on the osmoregulation and urine concentration mechanisms of the semi-desert rodent meriones shawi and eventual accumulation of this metal in vital organs such as the kidneys, which are directly implicated in water regulation. originally, we used differential pulse anodic stripping ...201222696068
effects of sub-chronic exposure to cadmium on some parameters of calcium and iodine metabolisms in the shaw's jird meriones shawi.in the present work we determined effects of a sub-chronic exposure to cadmium on some parameters of calcium and iodine metabolisms in meriones shawi, a desert rodent species occupying the arid steppes of tunisia and other countries. fourteen jirds of both sex were equally divided into a control group receiving diet without cadmium and a treated group receiving cadmium in the diet during 30, 45, 60 and 90 days. at the end of each period, 5 jirds from each group were sacrificed. in cadmium-treate ...201222516058
structural and neurochemical plasticity in both supraoptic and paraventricular nuclei of hypothalamus of a desert rodent meriones shawi after a severe dehydration versus opposite treatment by rehydration: gfap and vasopressin immunohistochemical study.various lines of evidence indicate that astrocytes can undergo morphological changes that modify their relationship to adjacent neurons in response to physiological stimulation such as dehydration. supraoptic (son) and paraventricular (pvn) nuclei of hypothalamus represent obvious examples of activity-dependent neuro-astrocytic plasticity. in the present study, meriones shawi is used as an animal model. moreover, gfap and vasopressin expressions are used as indicators successively of astrocytes ...201222445884
the anxiogenic-like effects of dehydration in a semi-desert rodent meriones shawi indicating the possible involvement of the serotoninergic system.dehydration is a powerful stimulus causing disequilibrium in homeostasis of water and electrolytes resulting from depletion in total body water. most studies have focused on domestic and laboratory animals; however, the study of desert animals allows improved understanding about water balance and resistance to dehydration and associated behavioral changes, including those related to mood disorders. meriones shawi (shaw's jird) is a desert rodent characterized by its resistance to long periods of ...201222172710
the in vivo antidiabetic activity of nigella sativa is mediated through activation of the ampk pathway and increased muscle glut4 content.the antidiabetic effect of n. sativa seed ethanol extract (nse) was assessed in meriones shawi after development of diabetes. meriones shawi were divided randomly into four groups: normal control, diabetic control, diabetic treated with nse (2 g eq plant/kg) or with metformin (300 mg/kg) positive control, both administered by daily intragastric gavage for 4 weeks. glycaemia and body weight were evaluated weekly. at study's end, an oral glucose tolerance test (ogtt) was performed to estimate insu ...201121584245
cellular plasticity in the supraoptic and paraventricular nuclei after prolonged dehydration in the desert rodent meriones shawi: vasopressin and gfap immunohistochemical study.supraoptic (son) and paraventricular (pvn) nuclei are part of the hypothalamic-neurohypophysial system, they constitute the main source for vasopressin and they represent also obvious examples of activity-dependent neuroglial plasticity. certain physiological conditions such as dehydration are accompanied by a structural remodeling of the neurons, their synaptic inputs and their surrounding glia. in the present work, an adult meriones shawi (a rodent adapted to desert life) is used as an animal ...201120971098
proopiomelanocortin in the arcuate nucleus of the rodent meriones shawi: effects of dehydration.proopiomelanocortin (pomc) is a 36kda glycoprotein implicated in homeostatic balance. we used in situ hybridization histochemistry coupled with quantitative autoradiography to determine the anatomical distribution of pomc mrna-expressing neurons in the arcuate nucleus (an) and to examine the effects of prolonged dehydration on pomc gene expression in a semi-desert rodent, meriones shawi (shaw's jird). in the hypothalamus of control animals, pomc mrna-expressing neurons were exclusively localized ...201120447683
water deprivation affects serotoninergic system and glycoprotein secretion in the sub-commissural organ of a desert rodent meriones shawi.water deprivation is a stress that has been associated with activation of several endocrine systems, including circumventricular organs of the central nervous system. the sub-comissural organ (sco), characterized by its glycoprotein secretion called reissner's fiber has been suggested to play a role in the regulation of body water balance. meriones shawi, a semi-desertic rodent characterized by its resistance to long periods of thirst was subjected to water deprivation for 1 and 3 months. effect ...200919716402
immunohistochemical evaluation of the effect of lead exposure on subcommissural organ innervation and secretion in shaw's jird (meriones shawi).the secretory activity of subcommissural organ cells is controlled by various extrinsic and intrinsic factors. lead has been recognised as a neurotoxic heavy metal, since it induces morphological and functional abnormalities in the brain. in this work, we examined the effect of lead exposure on the subcommissural organ (sco), a brain gland known by its secretion of reissner's fiber (rf) in cerebro-spinal fluid. glycoprotein secretion and serotonin (5ht) innervation of the sco was examined after ...200717707886
lactational transfer of cadmium from meriones shawi shawi mothers to their pups and its effects on calcium homeostasis and bone calcium in pups.cadmium (cd) was given to meriones shawi shawi dams in the diet (1 g cdcl2/1.5 kg of diet) from day 1 to day 21 of lactation. pups were killed at 5, 10, 14 and 21 days of lactation. thereafter, liver, kidney, femur and stomach content were removed and plasma was collected to element analyses. cd in stomach content, kidney, liver and femur and calcium (ca) in stomach content, femur and plasma were determined in pups by atomic absorption spectrophotometer. the results indicate that cd was transfer ...201316088093
postnatal secretion of the subcommissural organ of the meriones shawi: control of serotonin innervation.the postnatal development of the subcommissural organ (sco) glycoprotein secretion in form of reissner's fiber and the putative control of the serotonin innervation upon the sco activity were examined by immunohistochemistry in the semi-desert rodent, meriones shawi. abundant sco secretory material and numerous serotoninergic fibers reaching the sco were observed in newborns meriones. an increase of both secretory material and serotonin fibres density inside the sco was observed during postnatal ...200111172888
effects of food deprivation and metabolic fuel utilization on food hoarding by jirds (meriones shawi).food hoarding plays an important role in the energetic repertoire of a variety of mammalian species. both food hoarding and food intake have been examined in rodents using several energetic challenges including food deprivation, treatment with metabolic fuel blockers, and enhancement of fuel storage. in the present experiment, we examined food hoarding by female jirds (meriones shawi), a desert rodent species occupying the arid steppes and desert regions of egypt. jirds are prodigious hoarders i ...199910477056
identification of two arginase isoenzyme activities along the nephron of meriones shawi.conflicting theories on the existence of several renal arginase isoenzymes remain in debate. because the activity of arginase is high in two embryologically different nephron segments of the meriones shawi kidney, namely the cortical (cpst) and medullary (ospst) proximal straight tubule and the outer medullary collecting duct (omcd), we postulate that these nephron segments may contain different isoforms. isolated nephron segments were dissected from collagenase-treated kidneys. tubules were per ...19999914399
gaba uptake and phenotypic characteristics of the subcommissural ependymocytes of the semi-desertic rodent, meriones shawi: correlation with serotoninergic innervation.many studies have emphasized species differences in the serotoninergic innervation and phenotypic characteristics of the subcommissural organ in mammals. the post-natal distribution patterns of serotonin-containing fibers, the onset of gamma-aminobutyric acid uptake, and glial markers have been studied in the subcommissural organ of the semi-desertic rodent, meriones shawi, by using immunohistochemical and autoradiographic techniques. abundant serotoninergic fibers can be observed in the subcomm ...19968772158
development of the hypothalamic vasopressin system and nephrons in meriones shawi during ontogenesis.this study has evaluated the development of the hypothalamic vasopressin system and nephrons of the kidney in desert rodents, meriones shawi, which effectively retain water by excretion of highly concentrated urine. the vasopressin system was studied immunocytochemically at the 18th fetal day, at the 2nd, 13th, 27th postnatal days and in adulthood. the kidneys were investigated at the 2nd, 13th postnatal days and in adulthood using microdissection technique. occasional vasopressin-immunoreactive ...19968881477
sites of arginine synthesis and urea production along the nephron of a desert rodent species, meriones shawi.the distribution of arginine synthase and arginase activities along the successive nephron segments of meriones kidney was measured in vitro with single tubule enzymatic microtechniques making use of either l-[ureido-14c] citrulline (0.108 mm) or l-[guanidino-14c]arginine (0.2 mm) as the respective substrates. arginase activity (fmol urea formed per min per mm of tubule) was very low (5-25 fmol.min-1.mm-1) in most nephron segments including the early portions of proximal convoluted tubules (earl ...19957617438
seasonal variations of androgens and of several sexual parameters in male meriones shawi in southern morocco.seasonal changes of several parameters related to sexual activity were studied in the gerbil (rodentia: gerbillidae). the weight of the testes, seminal vesicles, and adrenals fluctuate throughout the year. plasma androgen levels and histological aspect of the testes also vary throughout the year. spermatogonial and steroid activities are synchronous and are maximal in winter and spring. the relationship between these activities and environmental climatic parameters is discussed: the beginning of ...19921601278
[effect of prolonged water deprivation on weight gain and water metabolism in a gerbillid rodent (meriones shawi shawi)].the effect of prolonged water deprivation, applied progressively since weaning, was studied on body weight in growing sub-desert rodents (meriones shawi). then, water metabolism, food consumption and kidney weight were measured in these adults animals. during partial water deprivation the weight curve was similar to that of controls, whereas with total water deprivation three different stages were noticed: a decrease, a stabilization and an increase in body weight as a function of age. at the en ...19873589137
laboratory tests of seven rodenticides for the control of meriones shawi.the response of meriones shawi to seven rodenticides was investigated in laboratory feeding tests. the species proved to be much less susceptible to anticoagulants than most other species of rodent pests. brodifacoum (at 0.005%), although giving complete mortality after only 8 days' continuous feeding, was more toxic than warfarin (0.025%), coumatetralyl (0.0375%), difenacoum (0.005%) and bromadiolone (0.005%). calciferol (0.1%), though toxic, was significantly unpalatable. zinc phosphide (5.0%) ...19836605985
transgelin: an androgen-dependent protein identified in the seminal vesicles of three saharan rodents.during the breeding season, a major androgen-dependent protein with an apparent molecular weight of 21 kda was isolated and purified from the seminal vesicles of three saharan rodents (mlvsp21 from meriones libycus, msvsp21 from meriones shawi, and mcvsp21 from meriones crassus). the 21-kda protein was isolated and purified from soluble seminal vesicle proteins of homogenate by one-dimensional polyacrylamide gel electrophoresis (sds-page). using polyclonal antibodies directed against posvp21 (ps ...201323906482
random x-chromosome inactivation in interspecific hybrids of meriones libycus (male) x meriones shawi (female) (rodentia: gerbillinae). 19715116146
the underlying physiological basis of the desert rodent meriones shawi's survival to prolonged water deprivation: central vasopressin regulation on peripheral kidney water channels aqps-2.meriones shawi (m. shawi) is a particular semi-desert rodent known by its resistance to long periods of thirst. the aim of the present investigation is to clarify the underlying mechanisms allowing m. shawi to resist to hard conditions of dehydration. for this reason we used two different approaches: i) a morphometric study, which consists in measuring the effect of dehydration on body and kidneys weights as well as the report kidney weight/body weight, ii) by immunohistochemistry, we proceed to ...201729217107
altered nigrostriatal dopaminergic and noradrenergic system prompted by systemic lead toxicity versus a treatment by curcumin-iii in the desert rodent meriones shawi.exposure to lead is a threat factor for neurodegenerative disorders progress as it could trigger dopaminergic deficiency. we aimed herein to assess the effect of acute lead exposure (25mg/kg b.w i.p.) during three continuous days on the dopaminergic and noradrenergic systems together with locomotor performance in meriones shawi (m. shawi), then the neuroprotective potential of curcumin-iii (30mg/kg b.w) by oral gavage. pb-exposed m. shawi exhibited increased tyrosine hydroxylase (th) immunoreact ...201931474522
epidemiological features of a recent zoonotic cutaneous leishmaniasis outbreak in zagora province, southern morocco.leishmania major is an endemic vector-borne disease in morocco that causes zoonotic cutaneous leishmaniasis (zcl), especially in arid pre-saharan regions where its unique vector and reservoir are phlebotomus papatasi and meriones shawi, respectively, and may cause epidemics. in late 2017, the zagora province, an endemic focus for zcl in southern morocco, had cl outbreak. the main objective of our investigation was to analyze the epidemiological features of this latest zcl outbreak.201930964864
crocus sativus restores dopaminergic and noradrenergic damages induced by lead in meriones shawi: a possible link with parkinson's disease.lead (pb) is a metal element released into the atmosphere and a major source of environmental contamination. the accumulation and concentration of this metal in a food web may lead to the intoxication of the body, more precisely, the nervous system (ns). in addition, pb-exposure can cause structural and functional disruption of the ns. studies have shown that pb-exposure could be a risk factor in the development of parkinson's disease (pd). the latter is related to dopaminergic deficiency that m ...201930573341
retinal dysfunction parallels morphologic alterations and precede clinically detectable vascular alterations in meriones shawi, a model of type 2 diabetes.diabetic retinopathy is a major cause of reduced visual acuity and acquired blindness. the aim of this work was to analyze functional and vascular changes in diabetic meriones shawi (m.sh) an animal model of metabolic syndrome and type 2 diabetes. the animals were divided into four groups. two groups were fed a high fat diet (hfd) for 3 and 7 months, two other groups served as age-matched controls. retinal function was assessed using full field electroretinogram (ff-erg). retinal thickness and v ...201830009825
characterization of vascular dysregulation in meriones shawi after high-calorie diet feeding.the present study was initiated to characterize vascular dysregulations (contraction and relaxation) associated with metabolic defects in merions shawi, a rodent from the gerbillidae family, submitted to 12 weeks high-calorie diet. this diet induces a type 2 diabetes/metabolic syndrome phenotype with hypertension. in diabetic meriones, body weight increase was associated with hyperglycemia, increased insulinemia, and insulin resistance. compared to lean meriones, diabetic meriones showed decreas ...201829420089
development of acanthocheilonema viteae in meriones shawi: absence of microfilariae and production of active es-62.es-62 is a well-studied anti-inflammatory molecule secreted by l4-adult stage acanthocheilonema viteae. we maintain the life cycle of a viteae using meriones libycus as the definitive host. here, we investigated whether the full life cycle could be maintained, and functional es-62 produced, in a related jird species-meriones shawi.202033091157
neuroprotective effects of oleuropein on retina photoreceptors cells primary culture and olive leaf extract and oleuropein inhibitory effects on aldose reductase in a diabetic model: meriones shawi.aldose reductase (ar) is an enzyme implicated in the development of diabetes complications among them diabetic retinopathy. erythrocyte ar activity was measured in control and diabetic meriones shawi, a type-2 diabetic model. we noticed an increase of ar activity in diabetic meriones by comparison to controls. olive leaf aqueous extract and oleuropein were tested for their inhibitory potential on ar activity. both exerted a partial in-vitro inhibition effect which was higher with the olive leaf ...202031922452
neurobehavioral effects of acute and chronic lead exposure in a desert rodent meriones shawi: involvement of serotonin and dopamine.lead (pb) is a non physiological metal that has been implicated in toxic processes affecting several organs and biological systems, including the central nervous system. several studies have focused on changes in lead-associated neurobehavioral and neurochemical alterations that occur due to pb exposure. the present study evaluates the effects of acute and chronic pb acetate exposure on serotoninergic and dopaminergic systems within the dorsal raphe nucleus, regarding motor activity and anxiety ...201931580902
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