| in-vitro activity of new carbapenem antibiotics: comparative studies with meropenem, l-627 and imipenem against pathogenic nocardia spp. | mics of two new carbapenems, meropenem and l-627, and imipenem were determined against 98 strains of the nocardia asteroides group (i.e. n. asteroides sensu stricto, nocardia farcinica and nocardia nova), 46 strains of nocardia brasiliensis and 17 strains of nocardia otitidiscaviarum. meropenem and l-627 were less active against the n. asteroides group than imipenem. among the three species of the n. asteroides group, n. nova was the most sensitive to all the carbapenems. meropenem was more acti ... | 1992 | 1506332 |
| clinical and laboratory features of nocardia nova. | recent studies have shown that nocardia asteroides isolates have five major antibiotic resistance patterns; one of these patterns identifies isolates of nocardia farcinica. in the current study, we investigated a second pattern characterized by susceptibility to ampicillin and erythromycin. this pattern was seen in 17% of 223 clinical isolates identified by standard techniques as n. asteroides and associated with diseases typical for nocardiae. biochemically, isolates with this drug pattern were ... | 1991 | 1774244 |
| [in vitro susceptibility of pathogenic nocardia to beta-lactam antibiotics, especially imipenem, a carbapenem antibiotic]. | in vitro antibacterial activity of 30 beta-lactam antibiotics including 2 beta-lactamase inhibitors (clavulanic acid and sulbactam) against 2 major pathogenic nocardia, i.e. nocardia asteroides group and nocardia brasiliensis was studied. among the antibiotics tested, a newly developed carbapenem antibiotic, imipenem (ipm), was found to be the most active, followed by oxacephem group antibiotic flomoxef (fmox). ipm exhibited activity against only n. asteroides group (n. asteroides, nocardia farc ... | 1989 | 2695658 |
| numerical analysis of the taxonomy of nocardiae and rhodococci. | the genera nocardia and rhodococcus were clearly differentiated in the present study. eleven characteristics were shown to be useful for differentiation between these two genera. nocardia asteroides sunsu stricto previously defined by tsukamura was divided into two taxa. one contained the type strain and was considered to retain the name nocardia asteroides in a new sense. another was named in the present study as nocardia nova sp. nov. tsukamura. the type strain of this species is atcc 33726. t ... | 1982 | 6763136 |
| use of yeast killer system to identify species of the nocardia asteroides complex. | we evaluated the ability of the yeast killer system to differentiate members belonging to the nocardia asteroides complex (nocardia asteroides, nocardia farcinica, and nocardia nova). nocardia strains were selected randomly from clinical isolates. type strains of each nocardia species and recognized killer yeasts were taken from different collections. a clear area of inhibition surrounding the yeast cells demonstrated a positive killer effect on nocardia spp. two yeast strains, pichia mrakii (k9 ... | 1995 | 7699072 |
| catheter-associated bacteremia with nocardia nova with secondary pulmonary involvement. | | 1994 | 7726895 |
| pneumonia caused by nocardia nova and aspergillus fumigatus after cardiac transplantation. | nocardia nova, a newly established species of the nocardia asteroides complex, has recently been characterized as a human pathogen. this report of a case of pneumonia caused by nocardia nova and aspergillus fumigatus in a patient after cardiac transplantation is the first reported infection caused by nocardia nova following its detailed description. accurate identification and susceptibility testing of the nocardia nova isolate allowed successful oral therapy with clarithromycin when therapy wit ... | 1993 | 8500477 |
| cutaneous nocardiosis caused by nocardia nova occurring in an hiv-infected individual: a case report and review of the literature. | | 1993 | 8509986 |
| nocardia pseudobrasiliensis sp. nov., a new species of nocardia which groups bacterial strains previously identified as nocardia brasiliensis and associated with invasive diseases. | we studied five strains of a new nocardia taxon recently identified among nocardia brasiliensis strains associated with invasive diseases (r. j. wallace, jr., b. a. brown, z. blacklock, r. ulrich, k. jost, j. m. brown, m. m. mcneil, g. onyi, v. a. steingrube, and j. gibson, j. clin. microbiol. 33:1528-1533, 1995) to determine their taxonomic status. several characteristics of these organisms, including the presence of chemotype iv cell walls, nocardomycolic acids, a predominant menaquinone simil ... | 1996 | 8573505 |
| maxillary sinusitis caused by nocardia nova. | | 1996 | 8816154 |
| activities of the glycylcyclines n,n-dimethylglycylamido-minocycline and n,n-dimethylglycylamido-6-demethyl-6-deoxytetracycline against nocardia spp. and tetracycline-resistant isolates of rapidly growing mycobacteria. | susceptibilities to the new semisynthetic tetracycline (tet) compounds n,n-dimethylglycylamido-minocycline (dmg-mino) and n,n-dimethylglycylamido-6-demethyl-6-deoxytetracycline (dmg-dmdot) were compared with those to doxycycline, minocycline, and tet for 198 tet-resistant (tetr) and 33 tet-susceptible (tets) clinical isolates of rapidly growing mycobacteria (rgm) including the mycobacterium fortuitum group, mycobacterium abscessus, mycobacterium chelonae, and mycobacterium mucogenicum and 68 iso ... | 1996 | 8849243 |
| [pseudotumor form of pulmonary nocardia infection (nocardia nova) in a renal transplant patient]. | the authors report a case of pulmonary nocardiosis due to nocardia nova occurring in a smoker who had a renal transplant. a pseudo-tumour was found on a standard x-ray and computerised tomography did not suggest the diagnosis. needle aspiration under computerised tomographic control enabled a diagnosis to be made. | 1996 | 8999479 |
| western blot monitoring of disseminated nocardia nova infection treated with clarithromycin, imipenem, and surgical drainage. | a case of disseminated infection due to nocardia nova with subcutaneous popliteal and retrosternal abscesses and lung involvement in an immunocompromised patient is reported. the patient did not respond to sulfonamide therapy. clinical recovery was obtained upon treatment with imipenem then clarithromycin. western blot studies revealed an antibody response to a known nocardia-specific 55-kda antigen in four successive sera samples collected in the period from the time of admission to seven month ... | 1996 | 9031879 |
| comparison of agar dilution, broth microdilution, disk diffusion, e-test, and bactec radiometric methods for antimicrobial susceptibility testing of clinical isolates of the nocardia asteroides complex. | an evaluation was undertaken to determine the optimal method for the in vitro susceptibility testing of 26 nocardia asteroides complex isolates to the following antimicrobial agents: amikacin, ampicillin, amoxicillin-clavulanate, ceftriaxone, ciprofloxacin, erythromycin, imipenem, minocycline, and trimethoprim-sulfamethoxazole. five testing methods were studied including the agar dilution, broth microdilution, and disk diffusion methods, the epsilometer test (e-test), and the bactec radiometric ... | 1997 | 9157140 |
| [nocardia nova pulmonary infection under treatment with fludarabine]. | | 1997 | 9246103 |
| nocardia nova causing pulmonary nocardiosis of black crakes (limnocorax flavirostra). | natural nocardial infection has been reported in many different species including mammals and fish, but reports in birds remain uncommon. eight juvenile black crakes (limnocoraxflavirostra) died unexpectedly at the basle zoo. necropsy revealed disseminated white, firm nodules, 1-3 mm in diameter, throughout the lung parenchyma. histologically, the lungs contained multiple, often confluent granulomas with central necrosis. delicate, gram-positive, 0.5- to 1.0-microm-wide, branching, occasionally ... | 1999 | 10421104 |
| antimicrobial susceptibility of nocardia nova isolated from five cats with nocardiosis. | from 1992 through 1997, 5 cats were admitted to the hospital because of chronic, nonhealing lesions containing draining tracts. exudate from 2 of the 5 cats contained macroscopically visible granules. on the basis of cytologic findings, lesions were described as pyogranulomatous. degenerative neutrophils and activated macrophages, along with slender, branching, gram-positive, partially acid-fast microorganisms, were observed in stained smears of exudates obtained from all 5 affected cats. nocard ... | 1999 | 10496134 |
| identification of nocardia species by restriction endonuclease analysis of an amplified portion of the 16s rrna gene. | identification of clinical isolates of nocardia to the species level is important for defining the spectrum of disease produced by each species and for predicting antimicrobial susceptibility. we evaluated the usefulness of pcr amplification of a portion of the nocardia 16s rrna gene and subsequent restriction endonuclease analysis (rea) for species identification. unique restriction fragment length polymorphism (rflp) patterns were found for nocardia sp. type strains (except for the n. asteroid ... | 2000 | 10618080 |
| nocardia infection of a joint prosthesis complicating systemic lupus erythematosus. | the authors report the case of a 43-year-old woman suffering from severe systemic lupus erythematosus treated with long-term prednisone, who developed nocardia nova infection on a hip prosthesis. sepsis occurred about two years after an episode of pulmonary nocardiosis with the same nocardia species, that was successfully treated by 12 months of antibiotics. a good outcome of the joint infection was observed in response to antibiotics and removal of the prosthesis. nocardiosis is a rare infectio ... | 2000 | 10866103 |
| [pneumonia from nocardia nova in lung cancer]. | the clinical and radiographic manifestations of pulmonary nocardiosis are nonspecific. the diagnosis depends of the clinical suspicion for alerting the microbiology laboratory to use special culture and identification methods to initiate the appropriate therapy early. a nocardia pneumonia in a locally advanced non small cell lung cancer patients is present. even after initiate the treatment the patient died. it is important to suspect the diagnosis of uncommon infection to begin the therapy. | 2000 | 11100536 |
| nocardia nova infection in a hiv-positive man. | | 2001 | 11368812 |
| madura foot: treatment of nocardia nova infection with antibiotics alone. | this case report documents the presentation of a 29-year-old woman with a deep nocardia nova infection of the foot involving the bones. the patient responded well to prolonged antibiotic therapy, with essentially complete resolution of her symptoms. the results suggest that surgical intervention in these unusual cases may be unnecessary and that good clinical results can be obtained pharmacologically. | 2001 | 11411876 |
| primary cutaneous nocardiosis due to nocardia nova in a healthy woman. | we describe a 68-year-old healthy woman with an unusual skin manifestation of mycetoma. a dark reddish erythematous plaque was present on the dorsum of the left hand for over 10 years. a skin biopsy revealed sulphur granules in the abscess, and nocardia nova was identified from the specimen. treatment with dapsone resulted in significant improvement. we review the clinical features of cutaneous n. nova infections. | 2001 | 11453927 |
| [pneumonia caused by nocardia nova]. | this is the first clinical report of a case of pneumonia caused by nocardia nova in japan. a 52 year-old woman who had received steroids and cyclophosphamide for six years because of polymyositis was admitted to our hospital for further examination. on admission she had a mild cough, and her chest radiography and computed tomography revealed bilateral multiple nodules, some of which were cavitated. she developed a cough productive of yellow sputum and fever up to 38 degrees c. examination of the ... | 2001 | 11579529 |
| nocardia pseudovaccinii sp. nov. | comparative 16s rdna studies of nocardia type and reference strains revealed that strain dsm 43406t, identified as nocardia vaccinii, was wrongly classified. the strain was aerobic, gram-positive and produced scarce, white, branched aerial mycelium and a beige-red substrate mycelium. the reverse side of the colonies was yellow-orange. it showed chemotaxonomic markers that were consistent with its classification in the genus nocardia. the mycolic acids had chain lengths from 50 to 58 carbon atoms ... | 2002 | 12361293 |
| the first isolation of nocardia nova from an hiv-1 infected individual in japan. | nocardia species are opportunistic pathogens of immunocompromised patients. we report a case of nocardia nova infection complicating pneumocystis carinii pneumonia (pcp) in an hiv-1 infected individual. a 27-year-old man with hemophilia a was admitted on october 17, 2000, with fever and dyspnea. cd4 cell counts were 5/microl on admission. prophylaxis against pcp was administered by inhalation of pentamidine isethionate because he was allergic to sulfamethoxazole-trimethoprim (smz-tmp). he was di ... | 2002 | 12525899 |
| nocardia veterana as a pathogen in north american patients. | the molecular methodologies used in our laboratories have allowed us to define a group of nocardia isolates from clinical samples which resemble the type strain of nocardia veterana. three patient isolates and the type strain of n. veterana gave identical and distinctive restriction fragment length polymorphisms (rflps) for an amplified portion of the 16s rrna gene. these three isolates and the n. veterana type strain also gave identical rflps for an amplified portion of the 65-kda heat shock pr ... | 2003 | 12791881 |
| [pulmonary infection due to nocardia nova]. | | 2003 | 14533999 |
| implantable defibrillator pocket infection and bacteremia caused by nocardia nova complex isolate. | nocardia spp. are common environmental organisms that, to our knowledge, have never been implicated as causing an implantable defibrillator or pacemaker infection. we describe a 70-year-old male with a recent implantable cardiac defibrillator revision and subsequent device infection and bacteremia caused by a nocardia nova complex isolate. | 2003 | 14605196 |
| nocardia kruczakiae sp. nov., a pathogen in immunocompromised patients and a member of the "n. nova complex". | molecular methodologies have become useful techniques for the identification of pathogenic nocardia species and for the recognition of novel species that are capable of causing human disease. two isolates recovered from immunocompromised patients were characterized as nocardia nova by biochemical and susceptibility testing results. the restriction fragment length polymorphism (rflp) patterns obtained by restriction endonuclease analysis (rea) of an amplified portion of the heat shock protein gen ... | 2004 | 15528707 |
| sporotrichoid nocardiosis caused by nocardia nova in a patient infected with human immunodeficiency virus. | | 2004 | 15533065 |
| multiple copies of the 16s rrna gene in nocardia nova isolates and implications for sequence-based identification procedures. | molecular investigation of two nocardia patient isolates showed unusual restriction fragment length polymorphism patterns with restriction endonuclease assays (rea) using an amplified portion of the 16s rrna gene. patterns typical of nocardia nova were obtained with rea of an amplified portion of the 65-kda heat shock protein gene. subsequent sequence analysis of the 16s rrna gene regions of these isolates showed the presence of ambiguous bases within an expected restriction endonuclease recogni ... | 2005 | 15956412 |
| nocardia jiangxiensis sp. nov. and nocardia miyunensis sp. nov., isolated from acidic soils. | the taxonomic positions of two soil actinomycetes, strains 117(t) and 43401(t), provisionally assigned to the genus nocardia were determined in a polyphasic study. the organisms were found to have phenotypic properties typical of members of the genus nocardia, and formed a distinct branch in the nocardia 16s rrna gene tree. it was evident from the phylogenetic data that the isolates were most closely, albeit loosely, associated with the type strains of nocardia nova and nocardia pseudobrasiliens ... | 2005 | 16166688 |
| nocardimicins g, h and i, siderophores with muscarinic m3 receptor binding inhibitory activity from nocardia nova jcm 6044. | in the screening for muscarinic m3 receptor binding inhibitors from microbial secondary metabolites, the extract of nocardia nova jcm 6044 was found to be highly active. bioassay-guided isolation led to the identification of three siderophores, nocardimicins g (1), h (2) and i (3). their chemical structures were determined by spectroscopic analysis using nmr and ms. 1 and 2 inhibited the binding of tritium-labeled n-methylscopolamine to the muscarinic m3 receptor with ki values of 0.44 microm an ... | 2005 | 16320761 |
| nodular non-necrotising anterior scleritis due to nocardia nova infection. | | 2007 | 16878113 |
| nocardia nova as the causative agent in spondylodiscitis and psoas abscess. | we describe here the first case of nocardia nova spondylodiscitis accompanied by a psoas abscess due to spreading from pulmonary nocardiosis. nocardia was cultured from all affected sites. after 1 year of an appropriate antimicrobial therapy and a surgical drainage of the abscess that was required, the patient's clinical condition had improved. | 2007 | 17197647 |
| bacterial degradation of poly(trans-1,4-isoprene) (gutta percha). | gutta percha, the trans-isomer of polyisoprene, is being used for several technical applications due to its resistance to biological degradation. in the past, several attempts to isolate micro-organisms capable of degrading chemically pure poly(trans-1,4-isoprene) have failed. this is the first report on axenic cultures of bacteria capable of degrading gutta percha. from about 100 different habitats and enrichment cultures, six bacterial strains were isolated which utilize synthetic poly(trans-1 ... | 2007 | 17259606 |
| pulmonary nocardia nova infection. | | 2007 | 17338975 |
| clinical and microbiological features of nocardiosis 1997-2003. | nocardiosis has been believed to be caused by the members of the nocardia asteroides complex and the nocardia brasiliensis species. however, recent advances in genotypic identification have shown that the genus exhibits considerable taxonomic complexity and the phenotypic markers used in the past for its identification can be ambiguous. the aim of this study was to assess the species distribution of nocardia isolates and to determine whether there are differences in pathogenicity or antimicrobia ... | 2007 | 17374898 |
| risk factors, clinical characteristics, and outcome of nocardia infection in organ transplant recipients: a matched case-control study. | risk factors for nocardia infection in organ transplant recipients have not been formally assessed in the current era of transplantation. | 2007 | 17443467 |
| nocardia nova aortitis after coronary artery bypass surgery. | cardiac nocardiosis is a rare disease that is nearly always associated with cardiac operation. we report the case of a patient with a 10-month history of intermittent fevers after coronary artery bypass operation who presented with progressive shortness of breath and fever. he was found to have a large aortic aneurysm secondary to nocardia nova infection likely transmitted during his original bypass operation. this is the first reported case of nocardia aortitis after coronary bypass operation a ... | 2007 | 17484997 |
| nocardia acidivorans sp. nov., isolated from soil of the island of stromboli. | a gram-positive, non-spore-forming bacterium (strain gw4-1778(t)) was isolated from soil of the italian island of stromboli. 16s rrna gene sequence similarity studies showed that strain gw4-1778(t) is a member of the genus nocardia, most closely related to nocardia pseudobrasiliensis (genbank accession no. dq659914; 98.6 %), nocardia nova (z36930; 98.6 %), nocardia niigatensis (ab092563; 98.4 %), nocardia jiangxiensis (ay639902; 98.0 %), nocardia uniformis (z46752; 98.0 %) and nocardia miyunensi ... | 2007 | 17551026 |
| successful treatment of nocardia nova bacteremia and multilobar pneumonia with clarithromycin in a heart transplant patient. | nocardia is an opportunistic pathogen in solid organ transplantation for which long-term sulfonamide therapy is considered the treatment of choice. we report a patient 7 months status post-orthotopic heart transplantation with nocardia nova bacteremia and pneumonia. initial treatment consisted of intravenous trimethoprim-sulfamethoxazole, which cleared blood cultures, but the patient subsequently went into renal failure and required alternative therapy. this report describes the first case of n ... | 2007 | 17580232 |
| nocardia terpenica sp. nov., isolated from japanese patients with nocardiosis. | two bacterial strains isolated from different hospitals in japan were subjected to a polyphasic analysis. strains ifm 0406 and ifm 0706(t), producers of novel terpenoid antibiotics, were found to have morphological, biochemical, physiological and chemotaxonomic properties consistent with their classification in the genus nocardia, except for the presence of mk-8(h(4)) as one of the predominant menaquinones in addition to the major menaquinone mk-8(h(4 omega-cyc)). the 16s rrna gene sequence simi ... | 2007 | 17625175 |
| brain abscess caused by nocardia nova. | nocardia nova is a newly identified species of the nocardia asteroides group and has recently been characterized as a human pathogen. to date, a few cases of n. nova pneumonia or subcutaneous abscess have been reported. we describe a patient with a brain abscess caused by n. nova in a patient receiving prednisolone and cyclophosphamide for nephrosis. surgical excision and antibiotic treatment of the brain abscess were successful. this is the first detailed report of central nervous system infect ... | 2008 | 18068051 |
| nocardia nova septic arthritis following total knee replacement: a case report. | we describe a case of nocardia nova septic arthritis following a total knee replacement. a 55-year-old obese woman was admitted to hospital 5 months after knee surgery with a 3-week history of pain, swelling, and restricted mobility in her left knee but no preceding trauma/injury. 30 ml of cloudy joint fluid was aspirated and an arthroscopic examination showed extensive fibrin formation and synovitis. an arthroscopic washout was carried out using 16 litres of saline, followed by total synovectom ... | 2007 | 18162695 |
| [disseminated nocardiosis in a child with acute lymphoblastic leukemia]. | nocardiosis is a rare infectious disease in children. we report here a disseminated nocardiosis in a child with acute lymphoblastic leukemia. the patient presented prolonged febrile neutropenia and nodular pneumopathy. based on the amplification of a 16s rdna, a pcr assay detected nocardia sp. in the patient's bronchoalveolar lavage (bal) fluid. culture of bal samples yielded nocardia nova colonies after 2 weeks of incubation. hepatic, splenic, renal and cerebral localisations were detected on e ... | 2008 | 18321687 |
| microbial degradation of 7-ketocholesterol. | 7-ketocholesterol (7kc) is an oxidized derivative of cholesterol suspected to be involved in the pathogenesis of atherosclerosis and possibly alzheimer's disease. while some oxysterols are important biological mediators, 7kc is generally cytotoxic and interferes with cellular homeostasis. despite recent interest in preventing the accumulation of 7kc in a variety of matrices to avoid adverse biological effects, its microbial degradation has not been previously addressed in the peer-reviewed liter ... | 2008 | 18344006 |
| nocardia infection in lung transplant recipients. | nocardia is a well-recognized pathogen in immunocompromised hosts, but the incidence of nocardia infections in lung transplant recipients is not well defined. a chart review from 1990 to 2007 at clarian hospital lung transplant center and indiana university medical center revealed nocardia infections in four of 410 lung transplant recipients despite prophylaxis. all infections were confined to lung and occurred at a median time of 315 d after transplantation. nocardia nova was isolated in two pa ... | 2008 | 18435787 |
| cerebral abscess caused by nocardia nova. | primary cerebral nocardiosis is very rare and the subgroup of the isolate has usually been defined as nocardia asteroides. we report an unusual patient with a cerebral abscess whose cultures were typical for n. nova. it was first isolated from an hiv-1 infected individual and has a distinctive antibiotic susceptibility among the species of n. asteroides. aggressive surgical and medical intervention is a must for these unusual pathogens. although our surgical strategy was successful, treatment of ... | 2008 | 18512172 |
| nocardiosis: an overview and additional report of 28 cases in cattle and dogs. | phenotypic characteristics, antimicrobial susceptibility profile, and clinical-epidemiological features of 28 nocardia strains isolated from 19 cases of bovine mastitis, eight cutaneous-subcutaneous lesions and one case of pneumonia in dogs were evaluated. microbiological, biochemical, cytological and scanning electron microscopy methods were used in diagnosis. nocardia asteroides type iv, nocardia otitidiscaviarum,nocardia nova (type iii) and nocardia farcinica (type v) were isolated from bovin ... | 2008 | 18516465 |
| primary sternal osteomyelitis caused by nocardia nova: case report and literature review. | a 51 year old woman without significant past medical history or risk factors for nocardia infection developed primary nocardia nova sternal osteomyelitis with mediastinal abscess, diagnosed with open biopsy. she required prolonged antibiotic therapy and had a favorable outcome. primary sternal osteomyelitis develops in the absence of a contiguous focus of infection, as opposed to secondary sternal osteomyelitis, which is usually a complication of sternotomy. staphylococcus aureus probably still ... | 2008 | 18833413 |
| comparative in vitro activities of nemonoxacin, doripenem, tigecycline and 16 other antimicrobials against nocardia brasiliensis, nocardia asteroides and unusual nocardia species. | the aim of this study was to assess the in vitro activities of nemonoxacin (a novel non-fluorinated quinolone), doripenem, tigecycline and 16 other antimicrobial agents against the nocardia species. | 2009 | 19398458 |
| assignment of reference 5'-end 16s rdna sequences and species-specific sequence polymorphisms improves species identification of nocardia. | 16s rdna sequence analysis is the most accurate method for definitive species identification of nocardiae. however, conflicting results can be found due to sequence errors in gene databases. this study tested the feasibility of species identification of nocardia by partial (5'-end 606-bp) 16s rdna sequencing, based on sequence comparison with "reference" sequences of well-annotated strains. this new approach was evaluated using 96 american type culture collection (n=6), and clinical (n=90) nocar ... | 2009 | 19639036 |
| nocardia callitridis sp. nov., an endophytic actinobacterium isolated from a surface-sterilized root of an australian native pine tree. | a novel actinobacterium strain, cap 290(t), was isolated from a surface-sterilized root of an australian native pine tree, callitris preissii. comparative 16s rrna gene sequence analysis showed that the strain belongs to the family nocardiaceae. strain cap 290(t) was most closely related to nocardia nova jcm 6044(t) (97.4 % 16s rrna gene sequence similarity) and nocardia terpenica ifm 0706(t) (96.7 %); similarity to other type strains of the genus nocardia ranged from 95 to 97 %. chemotaxonomic ... | 2010 | 19684327 |
| nocardia nova infection after primary anterior cruciate ligament reconstruction with tibialis anterior allograft. | | 2010 | 20375367 |
| seca1 gene sequence polymorphisms for species identification of nocardia species and recognition of intraspecies genetic diversity. | sequence analysis of the nocardia essential secretory protein seca1 gene (seca1) for species identification of 120 american type culture collection (atcc) and clinical isolates of nocardia (16 species) was studied in comparison with 5'-end 606-bp 16s rrna gene sequencing. species determination by both methods was concordant for all 10 atcc strains. seca1 gene sequencing provided the same species identification as 16s rrna gene analysis for 94/110 (85.5%) clinical isolates. however, 40 (42.6%) is ... | 2010 | 20810768 |
| nocardia endophytica sp. nov., a novel endophytic actinomycete isolated from oil-seed plant jatropha curcas l. | a novel actinomycete, designated strain klbmp 1256t, was isolated from the surface-sterilized stem of oil-seed plant jatropha curcas l. collected from sichuan province, south-west china, and was characterized in order to determine its taxonomic position. phylogenetic analyses based on 16s rrna gene sequences indicated that the isolate was closely related to members of the genus nocardia in the family nocardiaceae, being most closely related to nocardia callitridis cap 290t (98.4%) and nocardia n ... | 2010 | 20817835 |
| clinical disease caused by klebsiella in 2 unrelated patients with interleukin 12 receptor beta1 deficiency. | patients with interleukin 12 (il-12)p40 or il-12 receptor β1 (il12rβ1) deficiencies are prone to develop infections caused by mycobacteria and salmonella; other infections have only been rarely observed. in this report we describe 2 unrelated patients with complete autosomal recessive il12rβ1 deficiency who suffered from sepsis attributable to klebsiella pneumoniae. a mexican boy suffered from disseminated bacille calmette-guérin disease and infections caused by k pneumoniae and candida albicans ... | 2010 | 20855390 |
| disseminated nocardia nova infection. | we report the case of a 61-year-old female with ulcerative colitis on therapy with prednisone and azathioprine. the patient presented with fever, dry cough, a swollen lower extremity, and nodules on the right wrist and the scalp. computed tomography scans of the head, chest, abdomen, and pelvis revealed multiple lesions. aspirates and biopsies of the lower extremity cystic lesion, the wrist nodule, and the scalp nodule all grew out nocardia nova. the patient was treated with high-dose trimethopr ... | 2010 | 21037519 |
| susceptibility of 186 nocardia sp. isolates to 20 antimicrobial agents. | this study determined the antimicrobial susceptibilities of 186 clinical isolates of nocardia spp. isolated in gipuzkoa, northern spain, between 1998 and 2009. most isolates were recovered from respiratory samples, nocardia nova, n. farcinica, n. cyriacigeorgica, n. abscessus, and n. carnea being the species most frequently isolated. linezolid and amikacin were the only two antimicrobials to which all isolates were susceptible. the majority of n. flavorosea, n. carnea, and n. farcinica isolates ... | 2011 | 21402847 |
| susceptibility of rapidly growing mycobacteria and nocardia isolates from cats and dogs to pradofloxacin. | rapidly growing mycobacteria (rgm) and nocardiae can cause severe or refractory infections in cats and dogs. prolonged antibacterial therapy is required to cure these infections. as fluoroquinolones have been used in combination therapy for treating rgm infections, isolates from the mycobacterium smegmatis cluster (n=64), mycobacterium fortuitum cluster (n=17), and m. mageritense cluster (n=2), collected from feline and canine patients, underwent susceptibility testing to pradofloxacin. the mic( ... | 2011 | 21726965 |
| Genome Sequences and Characterization of the Related Gordonia Phages GTE5 and GRU1 and Their Use as Potential Biocontrol Agents. | Activated sludge plants suffer frequently from the operational problem of stable foam formation on aerobic reactor surfaces, which can be difficult to prevent. Many foams are stabilized by mycolic acid-containing Actinobacteria, the mycolata. The in situ biocontrol of foaming using phages is an attractive strategy. We describe two polyvalent phages, GTE5 and GRU1, targeting Gordonia terrae and Gordonia rubrupertincta, respectively, isolated from activated sludge. Phage GRU1 also propagates on No ... | 2012 | 22038604 |
| terrestrial actinomycetes from diverse locations of uttarakhnad, india: isolation and screening for their antibacterial activity. | uttarakhand region is less explored, but possess a great biodiversity. this diversity can be explored for isolation and characterization of new actinomycetes strains for seeking antimicrobial molecules. it can therefore be predicted that novel bioactive metabolite producing actinomycetes can be discovered to combat multidrug resistant bacterial pathogens. | 2013 | 24475340 |
| epidemiology and susceptibility to antimicrobial agents of the main nocardia species in spain. | the aims of this study were to explore the clinical distribution, by species, of the genus nocardia and to assess the antimicrobial susceptibilities of the 10 most prevalent species identified in spain. | 2017 | 27999029 |
| nocardiosis in 132 patients with cancer: microbiological and clinical analyses. | to correlate the microbiological and clinical features of infections caused by nocardia species. | 2014 | 25239419 |
| comparison of restriction enzyme pattern analysis and full gene sequencing of 16s rrna gene for nocardia species identification, the first report of nocardia transvalensis isolated of sputum from iran, and review of the literature. | nocardial infections occur in different organs of the body and are common in immune disorder diseases of individuals. the aim of this study was to assess nocardia species identification by phenotypic tests and molecular techniques applied to nocardiosis in iranian patients. in the current study, various clinical samples were collected and cultured on conventional media and using the paraffin baiting method. various phenotypic tests were performed. for accurate identification at the species level ... | 2016 | 27613736 |
| uncommon mandibular osteomyelitis in a cat caused by nocardia africana. | nocardiosis is an unusual infection in companion animals characterized by suppurative to pyogranulomatous lesions, localized or disseminated. cutaneous-subcutaneous, pulmonary and systemic signs are observed in feline nocardiosis. however, osteomyelitis is a rare clinical manifestation in cats. nocardia cyriacigeorgica (formerly n. asteroides sensu stricto), nocardia brasiliensis, nocardia otitidiscaviarum, and nocardia nova are the most common pathogenic species identified in cats, based on rec ... | 2012 | 23216681 |
| multisite reproducibility of the broth microdilution method for susceptibility testing of nocardia species. | antimicrobial susceptibility testing (ast) of clinical isolates of nocardia is recommended to detect resistance to commonly used antimicrobial agents; such testing is complicated by difficulties in inoculum preparation and test interpretation. in this study, six laboratories performed repetitive broth microdilution testing on single strains of nocardia brasiliensis, nocardia cyriacigeorgica, nocardia farcinica, nocardia nova, and nocardia wallacei. for each isolate, a total of 30 microdilution p ... | 2012 | 22219309 |
| molecular identification of nocardia isolates from clinical samples and an overview of human nocardiosis in brazil. | nocardia sp. causes a variety of clinical presentations. the incidence of nocardiosis varies geographically according to several factors, such as the prevalence of hiv infections, transplants, neoplastic and rheumatic diseases, as well as climate, socio-economic conditions and laboratory procedures for nocardia detection and identification. in brazil the paucity of clinical reports of nocardia infections suggests that this genus may be underestimated as a cause of human diseases and/or either ne ... | 2013 | 24340116 |
| molecular identification and antimicrobial susceptibility of nocardia spp. isolated from bovine mastitis in brazil. | nocardia spp. infections can cause severe damage to the mammary gland due to suppurative pyogranulomatous lesions and lack of clinical cure in response to conventional antimicrobial therapy. although nocardia infections are considered relatively uncommon in cows, there has been an apparent worldwide increase in the incidence of bovine mastitis caused by nocardia spp, perhaps due to environmental transmission of this ubiquitous pathogen. the objectives of present study were to determine: (i) spec ... | 2013 | 24060098 |
| molecular identification and antimicrobial resistance pattern of seven clinical isolates of nocardia spp. in brazil. | nocardia is a ubiquitous microorganism related to pyogranulomatous infection, which is difficult to treat in humans and animals. the occurrence of the disease is on the rise in many countries due to an increase in immunosuppressive diseases and treatments. this report of cases from brazil presents the genotypic characterization and the antimicrobial susceptibility pattern using the disk-diffusion method and inhibitory minimal concentration with e-test® strips. in summary, this report focuses on ... | 2015 | 26200967 |
| nocardia rayongensis sp. nov., isolated from thai peat swamp forest soil. | an actinomycete strain, ry45-3t, isolated from a peat swamp forest soil in rayong province, thailand, was characterized using a polyphasic approach. the strain belonged to the genus nocardia on the basis of morphological, physiological, biochemical and chemotaxonomic properties. cell-wall peptidoglycan contained meso-diaminopimelic acid. the n-acyl group of muramic acid in the cell wall was glycolyl type. the diagnostic sugars in whole-cell hydrolysates were galactose and arabinose. mk-8 (h4ω-cy ... | 2016 | 26873179 |
| disseminated nocardiosis associated with the isolation of nocardia nova in a longsnout seahorse hippocampus reidi (ginsburg). | | 2017 | 28084628 |
| clinical characteristics of pulmonary nocardiosis in immunocompetent patients. | pulmonary nocardiosis is a rare but potentially serious infection typically in immunosuppressed patients (isps). it is also known to occur in immunocompetent patients (icps). however, little is currently known regarding the clinical characteristics and radiographic findings of pulmonary nocardiosis specifically in icps. in this study, 30 patients with pulmonary nocardiosis were identified and 10 were considered to be colonized. of all patients with pulmonary nocardiosis, 12 patients were icps an ... | 2016 | 27615155 |
| nocardia nova causing empyema necessitatis afterlung re-transplantation: a case report. | we report herein a case of thoracic infection due to nocardia nova following lung re-transplantation performed for emphysema related to alpha-1-antitrypsin deficiency. the infection extended from the lung into the pleural space, thoracic wall, and mediastinum, presenting as pericarditis and empyema necessitatis. nocardia nova was identified by 16s ribosomal deoxyribonucleic acid (rdna) sequencing and phylogenetic analysis. according to a literature search of pubmed, lilacs and medline databases, ... | 2017 | 27598645 |
| keratitis due to nocardia nova after cataract surgery. | | 2017 | 27448807 |
| nocardiosis following hematopoietic stem cell transplantation. | nocardia species are ubiquitous environmental organisms that can cause a diverse spectrum of disease. clinical manifestations range from localized skin and soft tissue infections to life-threatening pulmonary, central nervous system, and/or disseminated infections. patients with hematologic malignancies undergoing hematopoietic stem cell transplantation (hsct) are at risk for nocardiosis, and further data in regard to characteristics of disease in this population are warranted. | 2016 | 26809666 |
| nocardia nova sphenoid sinusitis and infratemporal fossa abscess. | nocardia sinusitis is exceptional, as a medline search revealed only one published case. the authors report a case of sphenoid sinusitis complicated by infratemporal fossa abscess, which raised several diagnostic problems. | 2016 | 26471040 |
| stool isolation of nocardia nova in two immunomodulated patients with inflammatory bowel diseases. | | 2016 | 26325188 |
| nocardia prosthetic knee infection successfully treated by one-stage exchange: case report and review. | a 64-year-old man with a history of sarcoidosis on corticosteroids and azathioprine was admitted to our hospital with complaints of worsening left knee pain and swelling for the past 3 weeks. his past medical history is also significant for severe osteoarthritis requiring a cemented total left knee arthroplasty 1 year ago. diagnostic investigation during his hospital admission eventually led to the diagnosis of nocardia nova knee prosthetic joint infection in the setting of a disseminated nocard ... | 2015 | 25560058 |
| pulmonary nocardia nova infection after allogeneic hematopoietic stem cell transplantation. | we herein report the case of a 68-year-old man with a history of allogeneic hematopoietic stem cell transplantation for acute myelocytic leukemia in whom graft-versus-host disease (gvhd) developed in the gastrointestinal tract and liver five months after transplantation. in that same period, chest computed tomography showed infiltration in both upper lungs. we performed bronchoscopy to clarify the gvhd and pulmonary infection. nocardia nova was identified in the bronchoalveolar lavage fluid, and ... | 2014 | 24930664 |
| chronic conjunctivitis due to nocardia nova complex formation on a silicone stent: a case report and review of the literature. | nocardial conjunctivitis associated with silicone tubing is an extremely rare finding. the authors present a case of a 52-year-old woman with previous dacryocystorhinostomy and silicone tube placement 3 years prior who presented with od redness and discharge for 1 week. on examination, the patient was noted to have mucoid discharge and crusting surrounding the silicone tube. the tube debris was sampled, and the culture was positive for nocardia nova complex sensitive to trimethoprim/sulfamethoxa ... | 2015 | 24892274 |
| insights into the microbial degradation of rubber and gutta-percha by analysis of the complete genome of nocardia nova sh22a. | the complete genome sequence of nocardia nova sh22a was determined in light of the remarkable ability of rubber and gutta-percha (gp) degradation of this strain. the genome consists of a circular chromosome of 8,348,532 bp with a g+c content of 67.77% and 7,583 predicted protein-encoding genes. functions were assigned to 72.45% of the coding sequences. among them, a large number of genes probably involved in the metabolism of xenobiotics and hardly degradable compounds, as well as genes that par ... | 2014 | 24747905 |
| primary cutaneous nocardiosis caused by nocardia nova in a kidney transplant recipient. | nocardia nova is a rare aetiological pathogen for cutaneous nocardiosis. to the best of our knowledge, this is the first case of n. nova primary cutaneous infection in a kidney transplant recipient. identification was performed using 16s rrna and seca1 gene sequence analyses. the patient was not treated successfully by antibiotics alone. surgical debridement was required for successful treatment. | 2014 | 24143007 |
| microbial gutta-percha degradation shares common steps with rubber degradation by nocardia nova sh22a. | nocardia nova sh22a, a bacterium capable of degrading gutta-percha (gp) and natural rubber (nr), was used to investigate the gp degradation mechanism and the relations between the gp and nr degradation pathways. for this strain, a protocol of electroporation was systematically optimized, and an efficiency of up to 4.3 × 10(7) cfu per μg of plasmid dna was achieved. by applying this optimized protocol to n. nova sh22a, a tn5096-based transposon mutagenesis library of this bacterium was constructe ... | 2013 | 23220954 |
| nocardia nova mycetoma over forehead in a lepromatous leprosy patient. | we present a case of a 31-year-old male, a known patient with lepromatous leprosy with a type 2 lepra reaction, who presented with a slowly growing asymptomatic swelling with multiple discharging sinuses over the forehead that developed over 6 months. smears of the serosanguinous discharge on gram staining showed gram-positive branching filamentous bacilli, which on culture on blood agar showed chalky-white colonies. histology of the lesion showed suppurative granulomas with polymorphs surroundi ... | 2012 | 22863625 |
| [nocardia nova brain abscess]. | nocardia nova is an uncommon pathogen for human beings. we describe an immunocompetent patient who acquired multiple cerebral abscesses. a surgical drainage yielded a sulpha-trimethoprim susceptible n. nova strain. the patient recovered uneventfully after a prolonged treatment with sulpha-trimethoprim. | 2012 | 22552522 |
| first case of nocardia nova spinal abscess in an immunocompetent patient. | nocardia are a group of aerobic actinomycetes that are filamentous gram-positive, weakly acid-fast, and cause opportunistic infection in immunocompromised patients. primary nocardia infection mostly involves lung, skin and less commonly, the central nervous system (cns). among nocardia cns infections, spinal infection is extremely rare. we describe the first case of a spinal abscess caused by nocardia nova in an immunocompetent patient who experienced a penetrating facial injury six months earli ... | 2017 | 22552466 |
| [nocardia nova as cause of right sided pectoralis pyomyositis identified by mass spectrometry]. | | 2012 | 22386758 |
| actinomycetoma of the chest wall attributed to nocardia nova after reconstructive surgery. | a 29-year-old man, presented with multiple ulcers, nodules, abscesses, fistulae, and atrophic scars, over the right chest wall. six years prior, the patient had a car accident, which resulted in skin loss of the right arm, shoulder, thoracic wall. in addition, he suffered a supracondylar fracture; orthopedic surgery and skin grafts were required. material discharging from sinus tracts was obtained for mycological and bacteriological studies. direct microscopic examination revealed small white gr ... | 2012 | 22301041 |
| identification of three homologous latex-clearing protein (lcp) genes from the genome of streptomyces sp. strain cfmr 7. | rubber materials have greatly contributed to human civilization. however, being a polymeric material does not decompose easily, it has caused huge environmental problems. on the other hand, only few bacteria are known to degrade rubber, with studies pertaining them being intensively focusing on the mechanism involved in microbial rubber degradation. the streptomyces sp. strain cfmr 7, which was previously confirmed to possess rubber-degrading ability, was subjected to whole genome sequencing usi ... | 2017 | 28711667 |
| pulmonary nocardiosis: a clinical analysis of 30 cases. | objective pulmonary nocardiosis frequently develops as an opportunistic infection in patients with malignant tumor and is treated with steroids. this study was performed to clarify the clinical features of pulmonary nocardiosis in japan. methods the patients definitively diagnosed with pulmonary nocardiosis at our hospital between january 1995 and december 2015 were retrospectively investigated. results nineteen men and 11 women (30 in total) were diagnosed with pulmonary nocardiosis. almost all ... | 2017 | 28626172 |
| cryptic nocardia nova brain abscess postradiation treatment and neurosurgery in a patient with small cell lung cancer: a case report and review of the literature. | | 2017 | 28740899 |
| [disseminated nocardiosis caused by nocardia nova with brain abscesses and osteomyelitis in an immunocompetent patient]. | nocardia is an opportunist bacteria involved in patients with cellular immunodepression or chronic lung disease. the most frequent portals of entry are the respiratory tract by inhalation or direct inoculation through a cutaneous effraction. nocardiosis may be localised or disseminated. | 2017 | 28716481 |