| b-lymphocyte activation with an extract of nocardia brasiliensis. | an extract from the pathogenic actinomycete nocardia brasiliensis was mitogenic for murine lymphocytes. this deoxyribonucleic acid-synthetic response of whole spleen cells peaked after 48 h in culture at concentrations of nocardia extract ranging from 10 to 200 micrograms/ml. the extract appeared to be a mitogen for b lymphocytes since cultures of spleen cells from congenitally athymic nude (nu/nu) mice and of antithymocyte serum plus complement-treated spleen cells from conventional (+/+) mice ... | 1979 | 314931 |
| nocardia infections in congenitally athymic (nude) mice and in other inbred mouse strains. | the mortality rate and histopathological features of nocardia asteroides and nocardia brasiliensis infections in congenitally athymic (nude) mice of icr and c3h/eb origins were quite different from what we found for swiss white mice and other inbred mouse strains (namely, c57/bl/6j, new zealand black, balb/c, cba/lac, and c3h/eb). the immunocompetent littermates of the congenitally athymic mice occupied an intermediate position between their athymic siblings and swiss white mice in terms of thei ... | 1977 | 336547 |
| preliminary investigation of the use of the enzyme linked immunosorbent assay (elisa) in the serodiagnosis of mycetoma. | antibody levels in a small group of sudanese patients with clinically diagnosed mycetoma, and control groups were measured by countercurrent immunoelectrophoresis (cie) and enzyme linked immunosorbent assay (elisa). antigens were prepared from the following organisms: streptomyces somaliensis, actinomadura madurae, a. pelletieri, nocardia brasiliensis and madurella mycetomi. positive reactions were obtained in clinical cases against the homologous antigens in both cie and elisa; all heterologous ... | 1978 | 360443 |
| primary cutaneous nocardiosis. | seven patients with primary cutaneous nocardiosis were seen during a 20-month period. six patients had a history of local trauma to an extremity or did frequent yard work. the spectrum of clinical disease included cellulitis, pustules,pyoderma, or lymphocutaneous syndrome mimicking sporotrichosis. evidence of nocardia infection elsewhere was absent, and no patient had a serious underlying disease. nocardia brasiliensis was isolated from four cases, and n asteroides was identified in the other th ... | 1979 | 376887 |
| changes in host resistance caused by nocardia brasiliensis in mice: cross-protection against listeria monocytogenes. | listeria monocytogenes was used to study the rate of development, magnitude, and persistence of the antimicrobial resistance engendered by nocardia brasiliensis infection in mice. the growth of listeria in the liver and spleen was more effectively restricted in nocardia-infected mice than in noninfected animals. the development of delayed-type hypersensitivity to the nocardia antigen was closely correlated to the increased resistance to listeria, suggesting that both properties are the consequen ... | 1978 | 640748 |
| nocardia asteroides and nocardia brasiliensis infections in mice. | a model for nocardia asteroides and nocardia brasiliensis infections in swiss white mice has been established without the addition to the inocula of any form of adjuvant. serial histopathological studies revealed that these two actinomycetes cause lesions that are quite different in their features. an acute suppurative abscess characterizes the lesions of n. asteroides. in the case of n. brasiliensis infections a granuloma is produced in which a striking feature is the presence of large numbers ... | 1976 | 773837 |
| different degrees of morbidity, in the white mouse, induced by nocardia brasiliensis, nocardia asteroides and nocardia caviae. | the respective degrees of morbidity induced by 6 strains each of nocardia brasiliensis, n. asteroides and n. caviae were investigated by the method of inoculation in the plantar pad of the white mouse, using a suspension of these nocardiae at a concentration of 10 mg/0-1 ml., and inspecting the animals one month, two months and three months following inoculation. all of the strains of n. brasiliensis produced attack greater and more consistent than that of the other species, n. caviae and n. ast ... | 1976 | 793053 |
| lymphocutaneous nocardiosis due to nocardia brasiliensis. | a farmer had chaining lymphocutaneous granuloma on the right hand and arm. clinically the syndrome seemed typical for sporotrichosis. bacteriological examination revealed nocardia brasiliensis as the only etiologic agent. since 1920, eight similar cases of sporotrichoid nocardiosis have been reported from various parts of the world. to our knowledge, isolation of n brasiliensis has not been reported previously in this geographical area. | 1977 | 856052 |
| amyloidosis developing in experimental nocardia infections. | swiss white and c57/bl/6j mice inoculated repeatedly with either nocardia asteroides or nocardia brasiliensis organisms developed amyloidosis over a 7-month period. amyloidosis also developed in these mice within 6 weeks following a single large inoculum of either organism, but not in other in-bred mouse strains, suggesting a genetic influence in the pathogenesis of this form of secondary amyloidosis. | 1977 | 861163 |
| lymphocutaneous nocardia brasiliensis infection simulating sporotrichosis. | | 1977 | 906457 |
| serological reactions to nocardia antigens. | sera from 23 patients with nocardiosis were tested for the presence of precipitating antibodies against an extract of nocardia asteroides. sera from nine of 20 patients infected with nocardia asteroides and one of three sera from patients with nocardia brasiliensis produced one to three precipitin lines with the antigen. sera from eight of 55 patients with tuberculosis and 11 of 13 patients with leprosy also contained nocardia precipitins. none of 33 sera from patients with cryptococcosis, blast ... | 1975 | 1098461 |
| letter: nocardia brasiliensis mycetoma: treatment with co-trimoxazole. | | 1975 | 1130811 |
| sporotrichoid nocardia brasiliensis infection. response to potassium iodide. | a lymphocutaneous infection due to nocardia brasiliensis occurred in a maryland gardener. this infection responded rapidly and completely to potassium iodide therapy. | 1975 | 1190621 |
| proceedings: nocardia brasiliensis mycetoma. | | 1975 | 1190808 |
| disseminated nocardia brasiliensis infection. | we report a 40-year-old man with advanced hodgkin disease who received combination chemotherapy and developed disseminated nocardia brasiliensis infection. we discuss opportunistic infections in the compromised host, with particular reference to nocardial disease and certain biologic characteristics of that organism. | 1976 | 1259450 |
| [epidemiology of mycetoma in mexico: study of 2105 cases]. | a survey was carried out in mexico to determine the incidence and epidemiological characteristics of mycetoma. data was collected from a total of 2105 cases of mycetoma throughout a 30 year period (1956-1985), with an average incidence of 70 cases per year. results showed a sex distribution of 76.1% male and 23.9% females. age distribution indicated a 35% between 16 to 30 and 23% between 31 to 40 year old population. most cases occurred in land-workers (60.2%) and in housewives with rural reside ... | 1992 | 1308000 |
| lymphocutaneous nocardia brasiliensis infection acquired from a cat scratch: case report and review. | nocardia brasiliensis is a bacterium that is most commonly found in the soil. traumatic inoculation of n. brasiliensis into the skin is the most typical mode of acquisition of infection due to this organism. to the best of my knowledge, i report the first case of lymphocutaneous n. brasiliensis disease from a penetrating cat scratch of the skin, thereby establishing cats as vehicles for the transmission of this infection. treatment with penicillin produced a rapid resolution of all signs and sym ... | 1992 | 1420688 |
| cutaneous nocardiosis associated with insect bites. | we report the first case of cutaneous nocardiosis associated with insect bites. the patient received these insect bites while camping a few days before he presented to the emergency room. the patient was a healthy twenty-six-year-old man, who was asplenic as a result of a motor vehicle accident. he presented to the emergency room with fever, multiple insect bites to his left lower extremity with pustules, lymphangitis, and left inguinal adenopathy. he was hospitalized but his condition failed to ... | 1992 | 1424798 |
| review of nocardial infections in france 1987 to 1990. | on the basis of the numbers of nocardia strains referred to the national reference center for mycoses and antifungal agents (nrc), institut pasteur, paris, in the period from 1987 to 1990, it was estimated that between 150 and 250 cases of nocardiosis are diagnosed in france each year. a total of 63 clinical isolates were referred to the nrc and identified as nocardia asteroides (66.7%), nocardia farcinica (23.8%), nocardia brasiliensis (3.2%), nocardia otitidiscaviarum (4.8%) and nocardia carne ... | 1992 | 1425729 |
| properties of a partially purified acid phosphatase from pathogenic nocardia brasiliensis. | like many other bacteria, nocardia sp. possess acid phosphatase activity. in n. brasiliensis, a human and animal pathogen, this activity was resolved into two enzyme forms by native gel electrophoresis. one (isozyme i) was partially purified and characterized. it exhibited an estimated molecular weight on sds-page of 50 kda, a ph optimum of 5.2, and a km value of 1.25 mm for p-nitrophenylphosphate. the n. brasiliensis enzyme was stable at 4 degrees c for at least 24 h, but readily inactivated at ... | 1992 | 1435947 |
| the producer and biological activities of so-75r1, a new mutactimycin group antibiotic [corrected]. | the producer of so-75r1, a new anthracycline group antibiotic was identified as nocardia brasiliensis. so-75r1 was active against gram-positive bacteria, but not active against gram-negative bacteria or fungi. all tested nocardia brasiliensis strains as well as the producer itself were resistant to so-75r1, although four other pathogenic nocardia, i.e. n. asteroides, n. nova, n. farcinica and n. otitidiscaviarum were sensitive [corrected]. | 1992 | 1490875 |
| nocardia brasiliensis meningitis. | | 1992 | 1494536 |
| tumor necrosis factor and macrophage activation are important in clearance of nocardia brasiliensis from the livers and spleens of mice. | the roles of tumor necrosis factor (tnf) and macrophage activation in clearance of nocardia brasiliensis from balb/c mouse livers and spleens were evaluated. tnf activity was detectable in sera from animals at all stages of infection. treatment of infected mice with an antiserum against tnf significantly enhanced the experimental infection as judged by enumeration of cfu in the spleens and livers of infected mice. in another set of experiments, a population of activated macrophages from the peri ... | 1992 | 1500164 |
| sf2457, a new antibiotic related to amicetin. | a novel nucleoside antibiotic, sf2457, was isolated from the fermentation broth of nocardia brasiliensis sf2457. the structure of sf2457 was determined by degradation studies using alkaline hydrolysis and methanolysis. sf2457 is closely related to the amicetin group antibiotics. the antibiotic exhibited inhibitory activity against gram-positive and gram-negative bacteria. | 1992 | 1500349 |
| so-75r1, a new mutactimycin derivative produced by nocardia brasiliensis. | | 1992 | 1500368 |
| in-vitro activity of new carbapenem antibiotics: comparative studies with meropenem, l-627 and imipenem against pathogenic nocardia spp. | mics of two new carbapenems, meropenem and l-627, and imipenem were determined against 98 strains of the nocardia asteroides group (i.e. n. asteroides sensu stricto, nocardia farcinica and nocardia nova), 46 strains of nocardia brasiliensis and 17 strains of nocardia otitidiscaviarum. meropenem and l-627 were less active against the n. asteroides group than imipenem. among the three species of the n. asteroides group, n. nova was the most sensitive to all the carbapenems. meropenem was more acti ... | 1992 | 1506332 |
| disseminated nocardia brasiliensis infection with septic arthritis. | an unusual case of disseminated nocardia brasiliensis infection is presented. the patient, who had been receiving chronic dexamethasone therapy for 4 years, had pneumonia and septic arthritis of the left knee due to n. brasiliensis. to our knowledge, this is the first report from the united states of a synovial joint infection with this organism. disseminated disease due to n. brasiliensis is infrequently reported; it is most often seen in the immunocompromised patient and is often unresponsive ... | 1992 | 1520795 |
| preseptal cellulitis caused by nocardia brasiliensis. | | 1992 | 1524136 |
| mini-mycetoma due to nocardia brasiliensis. | | 1992 | 1568813 |
| nocardia brasiliensis infection in patients with aids. | | 1992 | 1576299 |
| antibody response to nocardia brasiliensis antigens in man. | a crude extract from n. brasiliensis cells grown in brain heart infusion culture was analyzed. it showed a complex mixture of at least 37 bands when resolved with the discontinuous buffer system of laemmli in a gradient sds-page. western blot analysis of 16 sera from n. brasiliensis-infected individuals always showed the recognition of six bands of 61, 49, 45, 42, 26, and 24 kilodaltons (kda). some other bands also reacted but with less intensity. sera from tuberculosis and leprosy patients reac ... | 1992 | 1576408 |
| isolation and purification of two immunodominant antigens from nocardia brasiliensis. | two immunogenic proteins from a crude extract of nocardia brasiliensis were purified to homogeneity. a 61-kda protein (p61) was isolated from a 50% ammonium sulfate precipitate in two steps. initially, p61 was obtained by electroelution in a 10% nondenatured preparative polyacrylamide gel electrophoresis (page). in a second step, the eluate from the nondenatured gel was run in a 12% sodium dodecyl sulfate (sds) preparative polyacrylamide gel. after elution, a single band was demonstrated by sds- ... | 1992 | 1583118 |
| nocardia brasiliensis soft tissue infection in an immunocompromised host. | | 1992 | 1641216 |
| beneficial effects of hyperbaric oxygen therapy in nocardia brasiliensis soft-tissue infection. | to report the success of hyperbaric oxygen therapy in the treatment of nocardia brasiliensis mycetoma. we believe this to be only the second report in the medical literature of hyperbaric oxygen therapy used in the therapy of nocardial disease. | 1991 | 1857290 |
| community acquired pneumonia: aetiology and prognostic index evaluation. | a 10 month prospective study of all adults admitted to waikato hospital with community acquired pneumonia was performed to assess aetiology, mortality, hospital stay, and the value of a prognostic index based on that obtained from a british thoracic society study. the 92 patients in the survey had a mean age of 56 (range 13-97) years. a microbiological diagnosis was established in 72%; streptococcus pneumoniae (33%), mycoplasma pneumoniae (18%), and influenza a virus (8%) were the most common mi ... | 1991 | 1907034 |
| disseminated nocardia brasiliensis infection: an unusual complication of immunosuppressive treatment for childhood dermatomyositis. | the use of steroids combined with cytotoxic drugs has increased in the last decade. the concomitant increase of opportunistic infections has contributed significantly to morbidity and mortality of patients treated with immunosuppressive agents. we describe a child with dermatomyositis who developed disseminated nocardia brasiliensis infection while receiving steroids and methotrexate. infectious etiology was established by gram stain. the patient was treated successfully. disseminated nocardia b ... | 1991 | 1941833 |
| acquired resistance of nocardia brasiliensis to clavulanic acid related to a change in beta-lactamase following therapy with amoxicillin-clavulanic acid. | previous studies have demonstrated that nocardia brasiliensis is susceptible to amoxicillin-clavulanic acid and that its beta-lactamases are inhibited in vitro by clavulanic acid. a cardiac transplant patient with disseminated infection caused by n. brasiliensis was treated with this drug combination with good response, but relapsed while still on therapy. the relapse isolate was found to be identical to the initial isolate by using genomic dna restriction fragment patterns obtained by pulsed fi ... | 1991 | 2039203 |
| acid and alkali as aids in differentiation of pathogenic nocardia and for their isolation from clinical specimens. | the tolerance of nocardia brasiliensis, nocardia asteroides and nocardia caviae to different concentrations of acids and alkalis was studied in this work. the purpose was to determine their use: (a) in the differentiation of species; (b) for decontamination of clinical materials during the isolation of pathogenic nocardia. the results showed (1) that both 2 m nh3 and 0.05 m h2so4 solutions are useful for differentiating species. they can also be used as a complementary method for identification. ... | 1991 | 2067559 |
| comparison of antigens from agents of actinomycetoma by immunodiffusion and electrophoresis procedures. | antigenic extracts were prepared from culture filtrates of the principal agents known to cause actinomycetoma, namely actinomadura madurae, actinomadura pelletieri, nocardia asteroides, nocardia brasiliensis, nocardia otitidis-caviarum, and streptomyces somaliensis. these antigenic preparations were compared by immunodiffusion (id), counterimmunoelectrophoresis (cie), line immunoelectrophoresis (lie) and rocket line immunoelectrophoresis (rlie), with rabbit antisera prepared against each of the ... | 1990 | 2126557 |
| use of partially purified 54-kilodalton antigen for diagnosis of nocardiosis by western blot (immunoblot) assay. | a western blot (immunoblot) assay is presented for the diagnosis of nocardiosis with a specific immunodominant 54-kilodalton (kda) antigen purified from a culture filtrate of nocardia asteroides by immunoaffinity chromatography. the chromatography column was prepared with immunoglobulin g obtained from sera from patients with lepromatous leprosy. unbound solutes consisted of specific, partially purified n. asteroides antigens, primarily a 54-kda band, accompanied by two others of 31 and 62 kda. ... | 1990 | 2179262 |
| cultivation of a nocardioform acid-fast chemoautotrophic bacterium from armadillo tissues infected with mycobacterium leprae. | a nocardioform bacterium was isolated from the spleen tissue of an armadillo infected with m. leprae and easily propagated in pure culture in mineral salt medium supplemented with only simple c and n sources (e.g., liquid paraffin, tetradecane, ammonium salts, urea, asparagine, gelatin, xanthin, hypoxanthin etc.). complex organic substances, e.g., tyrosin, casein, peptone, meat extract, egg proteins, serum, blood, yeast extract as well as medium 199, did not support the growth of this organism. ... | 1990 | 2188909 |
| nocardia brasiliensis peritonitis in a patient with aids. | | 1990 | 2220750 |
| comparison of species distribution and antimicrobial susceptibility of aerobic actinomycetes from clinical specimens. | to compare the species distribution and antimicrobial susceptibility of aerobic actinomycetes, we evaluated 366 isolates referred to the centers for disease control from october 1985 through february 1988. we used conventional biochemical tests to identify the various species. four species accounted for 191 (52%) of aerobic actinomycete isolates: nocardia asteroides (98 isolates), actinomadura madurae (42 isolates), streptomyces griseus (28 isolates), and nocardia brasiliensis (23 isolates). spu ... | 1990 | 2237117 |
| pulmonary cryptococcus neoformans and disseminated nocardia brasiliensis in an immunocompromised host. case report. | | 1990 | 2342607 |
| nocardia brasiliensis leg ulcer in a child. | | 1990 | 2352823 |
| acute primary cutaneous nocardiosis. | an acute localized, purulent skin lesion developed on the right knee of an 8-year-old girl and was subsequently diagnosed as a primary cutaneous nocardia brasiliensis infection. it was soon accompanied by intense lymphangitis and regional adenopathy. the patient had a history of a minor abrasion contaminated by soil at the site of infection 8 days before the infection became evident. the infection was successfully treated with a combination of minocycline and dapsone. | 1990 | 2394860 |
| monoclonal antibodies to nocardia asteroides and nocardia brasiliensis antigens. | nocardia asteroides and nocardia brasiliensis whole-cell extracts were used as antigens to generate monoclonal antibodies (mabs). six stable hybrid cell lines secreting anti-nocardia spp. mabs were obtained. these were characterized by enzyme-linked immunosorbent assay, western blot (immunoblot), and immunofluorescence assay. although all the mabs exhibited different degrees of cross-reactivity with n. asteroides and n. brasiliensis antigens as well as with culture-filtrate antigens from mycobac ... | 1990 | 2405017 |
| the efficiency of 1 m nh4cl and 2 m nacl for the isolation of pathogenic nocardia from soil. | the present paper reports an improvement to the classical method of the paraffin bait, by the usage of 1 m nh4cl or 2 m nacl to eliminate contaminant microflora of soil. the purpose is to introduce a change in the paraffin bait method in order to reduce time required to isolate pathogenic strains of nocardia from their natural sources. for this study three main criteria were used: a) determination of the inhibitory effect of different concentrations of salts on soil microflora; b) the tolerance ... | 1989 | 2594047 |
| mycetoma due to nocardia brasiliensis: first case report from the union territory of delhi. | the first case of mycetoma caused by nocardia brasiliensis from the union territory of delhi is reported. the patient, a permanent resident of the union territory of delhi, acquired the disease 10 years ago following an accidental injury to his right hand. the diagnosis of the case was made on the basis of demonstration of the grains in direct microscopy, isolation of the organism in culture directly from the grains, identifying the organism by the conventional tests and through histopathology o ... | 1989 | 2608095 |
| cutaneous abscess caused by nocardia brasiliensis: report of a case. | we report a case of cutaneous nocardia brasiliensis infection. the patient had received radiotherapy and anti-neoplastic chemotherapy for epidermoid carcinoma of the left sphenoid sinus with bone destruction. he developed fever and an ulcer on the dorsal medial surface of the left hand after an intravenous infusion of chemotherapeutic agents in the same site 3 days earlier. needle aspiration of the abscess disclosed polymorphonuclear leukocytes, and a partially acid-fast, gram-positive filamento ... | 1989 | 2636252 |
| [surgical treatment of mycetoma located in the face]. | the first case described in mexico, was studied by cícero in 1900 and 1911 ocaranza, in sonora, reports some cases, pointing out that the first known case dates back to 1874. in usa gonzález ochoa identifies the causative agent of the cases he studied, as the same identified in usa, but he calls attention to the fact that it has already been described under the name of actinomyces brasiliensis, finally, taxonomically it is included among the nocardias. in mexico the micetoma is caused in 90% of ... | 1989 | 2666793 |
| [in vitro susceptibility of pathogenic nocardia to beta-lactam antibiotics, especially imipenem, a carbapenem antibiotic]. | in vitro antibacterial activity of 30 beta-lactam antibiotics including 2 beta-lactamase inhibitors (clavulanic acid and sulbactam) against 2 major pathogenic nocardia, i.e. nocardia asteroides group and nocardia brasiliensis was studied. among the antibiotics tested, a newly developed carbapenem antibiotic, imipenem (ipm), was found to be the most active, followed by oxacephem group antibiotic flomoxef (fmox). ipm exhibited activity against only n. asteroides group (n. asteroides, nocardia farc ... | 1989 | 2695658 |
| physiological and pathogenic characteristics of nocardia brasiliensis isolated from human mycetomas. | a previous analysis of the physiological properties of nocardia brasiliensis strains isolated from soil of tucumán proves that non-pathogenic strains have a different behaviour pattern from the pathogenic strains. in the present paper, 16 nocardia brasiliensis strains isolated from human mycetomas were studied in the same way. the object is to determine if any of the nocardia brasiliensis present in soil can produce human mycetomas. the macro and micromorphological, biochemical (17 tests), physi ... | 1989 | 2747785 |
| [disseminated nocardiosis due to nocardia brasiliensis in an ambulatory patient]. | we report the case of a 76-year-old man with generalized nocardiosis. the microbiologic pattern, the different clinical manifestations and the treatment of nocardiosis are discussed in general. in the particular case of our patient the disease manifested itself primarily as a subcutaneous abscess, a metastasis secondary to pulmonary nocardiosis. the disease was caused by a nocardia brasiliensis, which is rarely seen in europe and which does not usually cause a generalized form of nocardiosis. | 1989 | 2756262 |
| [cerebral manifestation of nocardia brasiliensis infection]. | | 1987 | 3031771 |
| primary lymphocutaneous nocardia brasiliensis infection: three case reports and a review of the literature. | the occurrence of human nocardiosis is increasing in both immunocompetent as well as immunosuppressed patients. we report three rare cases of primary lymphocutaneous nocardia brasiliensis infection. the mode of inoculation in each case was that of a puncture wound that occurred 1-3 wk prior to the development of the clinically apparent infections. the original clinical diagnosis was erroneous in each case. a review of 16 previously reported cases is presented as well as a discussion of appropria ... | 1988 | 3066569 |
| in vitro susceptibilities of nocardia species to newer antimicrobial agents. | the in vitro activities of various quinolones, two newer cephalosporins, and imipenem against 23 strains of nocardia asteroides, 4 strains of nocardia brasiliensis, and 4 strains of nocardia caviae were determined by an agar dilution method. pd-117558, a newer carboxyquinolone, and imipenem were the most active agents tested, inhibiting 90% of n. asteroides isolates at an mic of 2 micrograms/ml. of the 23 strains of n. asteroides, 15 were susceptible to cefpirome and 10 were susceptible to cipro ... | 1988 | 3190193 |
| acid phosphatase activity in nocardia brasiliensis and nocardia asteroides. | nocardia asteroides and n. brasiliensis strains were found to possess acid phosphatase activity. this enzyme was found to be cell-associated and its activity paralleled the cell mass increase seen during the nocardia growth cycle. of the strains tested, n. brasiliensis exhibited the highest enzymatic activity. implications of these findings are related to current evidence which indicates that other microbial acid phosphatases may constitute potential pathogenic factors for humans. | 1988 | 3287423 |
| [high-dosage cotrimoxazole therapy of disseminated nocardia brasiliensis infection]. | after a scraping injury to the skin a 47-year-old man developed a generalized nocardia brasiliensis infection with cutaneous, pulmonary and cerebral dissemination. there was no predisposing underlying illness. high-dosage cotrimoxazol and short-term intrathecal and systemic gentamycin administration achieved extensive healing. this form of treatment would thus seem capable of reversing the otherwise poor prognosis of generalized n. brasiliensis infection. | 1986 | 3484699 |
| mycetoma due to nocardia caviae. | mycetoma is the most frequent deep mycosis in mexico and is caused by nocardia brasiliensis in 86% of the cases. two cases of mycetoma due to nocardia caviae, the first in mexico, are reported. the strains were identified by their biochemical properties according to the criteria of gordon and mihm (1962). few cases of mycetoma caused by this actinomycete have been reported in the world. one of our cases was unusual: occurring on the trunk as a tumor and diagnosed by finding the "grains" on histo ... | 1987 | 3494691 |
| beta-lactam resistance in nocardia brasiliensis is mediated by beta-lactamase and reversed in the presence of clavulanic acid. | forty clinical isolates and the type strain of nocardia brasiliensis were screened for susceptibility to 20 beta-lactams. isolates exhibited a single pattern of resistance, with large zones of inhibition by disk diffusion and low mics by broth and agar dilutions only to cefotaxime, ceftriaxone, ceftizoxime, augmentin, and timentin. all strains produced beta-lactamase, with five different enzyme patterns by isoelectric focusing. despite the differences in their isoelectric points, the enzymes had ... | 1987 | 3500241 |
| intracerebral nocardia brasiliensis infection. | case report about cerebral infection with the species nocardia brasiliensis in a not immunocompromised host. diagnosis, treatment and neuroradiological findings are shown and compared with current studies. | 1987 | 3506148 |
| lymphocutaneous nocardiosis caused by nocardia asteroides. case report and literature review. | a 22-year-old man developed erythematous nodules and an ulcer mimicking sporotrichosis on his right hand and forearm, which was subsequently diagnosed as lymphocutaneous nocardiosis caused by nocardia asteroides. to our knowledge, 21 cases of lymphocutaneous nocardiosis have been reported, with the majority of those cases, except for a few that remain uncertain, being due to nocardia brasiliensis. the case reported herein, the first known definitive case caused by n asteroides (to our knowledge) ... | 1986 | 3532961 |
| relationships between the physiological characteristics and pathogenicity of nocardia brasiliensis. | the analysis of 19 physiological properties of 28 strains of nocardia brasiliensis isolated from soil reveal differences which could be of great value in distinguishing pathogenic from nonpathogenic strains. | 1987 | 3587331 |
| nocardia brasiliensis skin infections. | nocardia brasiliensis skin infections were diagnosed in three patients (two with mycetoma and one with lymphocutaneous syndrome) in our hospital during the last 6 years. the mycetomas were detected in otherwise healthy yemenite immigrants who had acquired their infection while in yemen. the patient with the lymphocutaneous syndrome--a man with well-controlled diabetes mellitus--acquired his illness in israel. n. brasiliensis appears to be more common in our region than previously believed. this ... | 1986 | 3744789 |
| primary lymphocutaneous nocardia brasiliensis infection. | we report a rare case of primary lymphocutaneous nocardia brasiliensis infection occurring in an elderly diabetic man maintained on long-term therapy with prednisone. the mode of inoculation was that of a puncture wound caused by a contaminated needle that occurred one month prior to the development of the clinically apparent infection. the course of this patient's infection was protracted and required two surgical procedures and several months of antibiotic therapy. a review of 15 previously re ... | 1986 | 3767403 |
| disseminated nocardia brasiliensis infection following cryptococcal disease. | nocardiosis is an increasing clinical problem, especially in immunocompromised patients. the offending species is almost always nocardia asteroides. cryptococcosis is also an increasing problem in the immunosuppressed. we describe a patient with probable disseminated cryptococcosis followed by disseminated nocardia brasiliensis infection. only eight patients with disseminated n brasiliensis infection have been described, to our knowledge, in the united states. | 1986 | 3767404 |
| mouse toxicity induced by lipids and cell walls isolated from actinomycetes. | the possibility was examined that the toxicity induced in mice by actinomadura madurae, 'streptomyces pelletieri' and nocardia brasiliensis was due to lipid and cell-wall constituents. mice were inoculated intraperitoneally with heat-killed bacteria, lipid extracts and cell-wall preparations emulsified in mineral oil: toxicity was evaluated by recording weight loss and deaths. killed cells and cell-wall preparations of all three actinomycetes produced a pronounced loss of body weight, tissue nec ... | 1986 | 3794660 |
| studies on the pathogenesis of actinomycotic mycetoma in animals injected with fractions isolated from nocardia brasiliensis. | in the present study the participation was evaluated of isolated fractions of nocardia brasiliensis in the genesis of the inflammatory response observed in actinomycotic mycetoma. subcutaneous injection in mice of a suspension containing a polysaccharide fraction f1 obtained by treating cell walls with sodium hydroxide induced an inflammatory response at the inoculation site which was characterized by a large influx of polymorphonuclear (pmn) and mononuclear (mn) leucocytes between the 2nd and 4 ... | 1987 | 3814496 |
| detection of metabolites by frequency-pulsed electron capture gas-liquid chromatography in serum and cerebrospinal fluid of a patient with nocardia infection. | serum (sr) and cerebrospinal fluid (csf) from a patient suspected of having tuberculous meningitis were submitted to our laboratory for analysis by frequency-pulsed electron capture gas-liquid chromatography (fpec glc). the samples were tested for the presence of carboxylic acids, alcohols, hydroxy acids, and amines by methods described previously (c. c. alley, j. b. brooks, and d. s. kellogg, jr., j. clin. microbiol. 9:97-102, 1977; j. b. brooks, c. c. alley, and j. a. liddle, anal. chem. 46:19 ... | 1987 | 3818936 |
| subcutaneous abscesses caused by nocardia brasiliensis complicated by malignant lymphoma. a survey of cutaneous nocardiosis reported in japan. | a 47-year-old japanese man suffering from t-cell leukemia was examined for multiple subcutaneous abscesses followed to abrasion wound on his right knee. the causative organism was clustered, fine-branched filaments in pus aspirated from the lesions, identified as nocardia brasiliensis. most of the lesions regressed from the combined therapy of sulfamethoxazole and trimethoprim, leaving an ulcer on the patient's left leg. the nocardiosis cases in japan until 1984, including this one, were briefly ... | 1985 | 3877005 |
| septic arthritis due to nocardia brasiliensis. | | 1985 | 3910830 |
| fusion of normal rabbit alveolar macrophages induced by supernatant fluids from bcg-sensitized lymph node cells after elicitation by antigen. | cell-free supernatant fluids obtained from bcg-sensitized lymph node cells (6 x 10(6) cell/ml) incubated in tissue culture flasks containing heat-killed bcg (5 mug/ml) induced extensive development of multinucleated giant cells when incubated with normal alveolar macrophages. in contrast, supernatant fluids obtained after incubation of similar samples of the same lymph node cell population in flasks with (i) no mycobacteria, (ii) heat-killed escherichia coli, or (iii) heat-killed bacillus subtil ... | 1974 | 4131544 |
| [nocardia brasiliensis in czechslovakia. comparative studies of 2 strains isolated from mycetomas]. | | 1968 | 4234462 |
| [in vitro sensitivity of nocardia brasiliensis to various antibiotics and therapeutic drugs]. | | 1974 | 4468453 |
| fatal infection by nocardia brasiliensis in an armadillo. | | 1972 | 4553716 |
| chemotherapeutic sensitivity and viability of nocardia asteroides and nocardia brasiliensis in drugs. | | 1973 | 4584078 |
| mycetomas caused by curvularia lunata, madurella grisea, aspergillus nidulans, and nocardia brasiliensis in sudan. | | 1973 | 4584205 |
| mycetoma of the foot caused by nocardia brasiliensis. | | 1972 | 4624524 |
| lymphocutaneous nocardia brasiliensis infection mimicking sporotrichosis. | | 1973 | 4698772 |
| disseminated nocardia brasiliensis infection. | | 1973 | 4701385 |
| nocardia brasiliensis infection in the united states: a report of nine cases and a review of the literature. | | 1973 | 4720402 |
| systemic nocardiosis caused by nocardia brasiliensis. | | 1974 | 4809153 |
| [presence of an antigen in mycobacterium lepraemurium which is also common in mycobacterium leprae and nocardia brasilensis]. | | 1967 | 4971556 |
| mycetoma due to nocardia brasiliensis. | | 1970 | 4989461 |
| rifkind d: nocardia brasiliensis lymphocutaneous syndrome. | | 1971 | 5102581 |
| [treatment of mycetoma caused by nocardia brasiliensis using a new sulfamide administered once a week]. | | 1965 | 5263083 |
| mycetoma by nocardia brasiliensis successfully treated with ethambutol. | | 1969 | 5368017 |
| primary chancriform syndrome caused by nocardia brasiliensis. | | 1966 | 5900706 |
| mycetoma caused by nocardia brasiliensis in missouri. case report. | | 1966 | 5946294 |
| electron microscopic studies on granules of nocardia brasiliensis in man. | | 1966 | 5977763 |
| [action "in vitro" of a sulfonamide, ro-44393, on actinomyces brasiliensis (nocardia brasiliensis)]. | | 1966 | 5997146 |
| sporotrichoid nocardiosis caused by nocardia brasiliensis. | | 1967 | 6023043 |
| sensitivity to capreomycin and prothionamide in strains of mycobacterium, nocardia, rhodococcus, and related taxa for taxonomical purposes. | sensitivity to capreomycin and to prothionamide was analysed for 150 strains belonging to the genera mycobacterium, nocardia, rhodococcus, and related taxa. the analyses showed, e.g., that strains of mycobacterium chelonei and nocardia brasiliensis were more resistant to capreomycin than the other strains tested and that m. farcinogenes differed from m. senegalense concerning sensitivity to this drug. the analysis showed, furthermore, that strains of mycobacterium differ from those of nocardia, ... | 1983 | 6196927 |
| failure of sulfonamides and trimethoprim in the treatment of nocardiosis. | an immunocompromised patient with nocardia brasiliensis pneumonia and empyema acquired disseminated disease due to nocardia asteroides and died. the treatment of choice for pulmonary or disseminated nocardiosis is 6 to 12 g/day of sulfisoxazole (or adjusted dosage to achieve a serum level of 100 to 150 mg/l) continued for six to 18 months. combination therapy may be beneficial in selected patients; if trimethoprim therapy is used with sulfonamides, higher than usual doses of trimethoprim may be ... | 1983 | 6337576 |
| purification and partial characterization of a nocardia brasiliensis extracellular protease. | nocardia brasiliensis possess proteolytic activities that can be readily detected in a variety of media. in a modified formulation of a growth medium originally used for streptomyces aureofaciens, n. brasiliensis was found to secrete proteolytic enzymes, one of which was capable of hydrolyzing casein. this enzyme was purified to homogeneity from cell-free culture filtrates of n. brasiliensis. the purification procedure included ion-exchange chromatography on carboxymethyl-sepharose, gel filtrati ... | 1984 | 6363390 |
| [mycetoma in northern argentina]. | from 1972 to october 1982 we have observed 39 cases of mycetoma in the skin department of the hospital del milagro, salta (argentina). the diagnosis was based on the clinical aspect, mycological studies and in most cases histopathology was done as well. the mayoritary of the patients were farmers. from the clinical point of view there si a true prevalence of nocardia brasiliensis. most of the mycetomas can be found in the lower limbs. some of the patients presented quite severe lesions and eight ... | 1983 | 6366400 |
| preliminary evaluation of a passive hemagglutination assay and enzyme-linked immunosorbent assay for actinomycetoma caused by nocardia brasiliensis. | | 1984 | 6368227 |
| the clinical spectrum of nocardia brasiliensis infection in the united states. | seven cases of infection due to nocardia brasiliensis were identified over a 13-year period at duke university medical center, durham, north carolina. these seven cases and a review of 55 cases in the literature reported from the united states show that n. brasiliensis can cause a wide spectrum of disease. forty-six of the 62 patients had disease of skin and soft tissues. cutaneous manifestations included cellulitis, pustules, ulcerations, pyoderma, subcutaneous abscesses, a lymphocutaneous synd ... | 1984 | 6374833 |
| disseminated cutaneous nocardia brasiliensis infection. | nocardia brasiliensis is an uncommon pathogen in the united states despite its presence in soil samples. it is most frequently seen in patients who are immunosuppressed, but can occur in the immunocompetent host also. usually in a healthy host the infection is localized to one area of the body. disseminated infection was diagnosed in a healthy child who recovered fully after initiation of oral sulfonamide therapy. we suspect that the source was soil to which the patient was exposed during a fami ... | 1984 | 6504778 |