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[the in vitro action of plants on vibrio cholerae].natural products of several plants, according to the geographic location, are used by peruvian people in the popular treatment of diarrhea, with good success. when cholerae cases appeared in peru, we were interested to know the "in vitro" effect against vibrio cholerae 01, of these useful plants to treat diarrhea. the following plants were tested: cichorium intybus, althaea officinalis, psorela glandulosa, geranium maculatum, punica granatum, malus sativa, cydonia oblonga, chenopodium ambrosoide ...19948018898
incidence of aflatoxin producing strains and aflatoxin contamination in dry fruit slices of quinces (cydonia oblonga mill.) from the indian state of jammu and kashmir.an investigation was undertaken to obtain data on the occurrence of aflatoxins and the aflatoxin producing potential of aspergillus flavus strains isolated from dry fruit slices of quinces produced in jammu and kashmir, india. a total of 147 a. flavus isolates recovered from dr fruit slices were grown in liquid rice flour medium and screened for the production of various aflatoxins by thin layer chromatography. the results showed that 23.14% of the tested isolates were aflatoxigenic, producing a ...199911189744
plant antimutagens and their mixtures in inhibition of genotoxic effects of xenobiotics and aging processes.the antimutagenic effect of the bioactive compounds from fruits of morus alba l. (ma), punica granatum l. (pg), diospyros kaki l. (dk), cydonia oblonga mill. (co) and roots of glycyrrhiza glabra (gg) were investigated. the antimutagenic effects of compounds separately as well as their action in complex mixtures were studied on mutations induced by genotoxicants (x-rays, n-methylnitrosourea, cyclophosphamide, naf) and aging in bone marrow cell chromosomes from mice and rats. when tested separatel ...200212570329
purification and characteristics of sorbitol-6-phosphate dehydrogenase from loquat leaves.to study the role of sorbitol-6-phosphate dehydrogenase in sorbitol synthesis in leaves of rosaceous plants, properties of the enzyme and its presence in several plants in the family was investigated. the activity of the enzyme, which catalyzes an nadp-dependent oxidation of the substrate to glucose-6-phosphate, was detected in leaves of prunus mume, prunus persica, rhaphiolepsis indica, sorbus aucuparia, cydonia oblonga, photinia glabra, sorbaria kirilowii, and spiraea thunbergii.the enzyme was ...198116661650
medicinal plants used in kirklareli province (turkey).in this paper, 126 traditional medicinal plants from kirklareli province in turkey have been reported. one hundred and twenty six plant species belonging to 54 families and among them 100 species were wild and 26 species were cultivated plants. most used families were rosaceae, labiatae, compositae and the most used plants were cotinus coggyria, sambucus ebulus, achillea millefolium subsp. pannonica, hypericum perforatum, matricaria chamomilla var. recutita, melissa officinalis subsp. officinali ...200717257791
evaluation of free radical-scavenging and antihemolytic activities of quince (cydonia oblonga) leaf: a comparative study with green tea (camellia sinensis).this study aimed to determine the phenolic profile and to investigate the antioxidant potential of quince (cydonia oblonga) leaf, comparing it with green tea (camellia sinensis). for these purposes, methanolic extracts were prepared and phenolics content of quince leaf was determined by hplc/uv. the antioxidant properties were assessed by folin-ciocalteu reducing capacity assay and by the ability to quench the stable free radical 2,2'-diphenyl-1-picrylhydrazyl (dpph) and to inhibit the 2,2'-azob ...200919271320
protective effect of quince (cydonia oblonga miller) fruit against oxidative hemolysis of human erythrocytes.the aim of this study was to determine the phenolic content and evaluate the antioxidant activity of quince (cydonia oblonga) fruit. for this purpose, fruits were separated into pulps, peels and seeds and methanolic extracts were prepared. the phenolic profiles were determined by hplc/uv and antioxidant properties were studied for their ability to quench the stable free radical 2,2'-diphenyl-1-picrylhydrazyl (dpph) and to inhibit the 2,2'-azobis(2-amidinopropane) dihydrochloride (aaph)-induced o ...200919306906
anti-allergic effect of a hot-water extract of quince (cydonia oblonga).we examined the effect of a crude hot-water extract (hw) of quince (cydonia oblonga miller) fruit on type i allergy in vivo and in vitro. the oral administration of the quince hw-added diet to nc/nga mice for 63 d showed a significant decrease in the development of atopic dermatitis-like skin lesions under conventional conditions. the concentration of ige in the serum collected from mice fed with quince hw was also lowered in a dose-dependent manner. moreover, we found that quince hw inhibited t ...200919661701
hypoglycemic activity and antioxidant potential of some medicinal plants traditionally used in turkey for diabetes.cydonia oblonga mill. (rosaceae) leaves, helianthus tuberosus l. (asteraceae) tubers, and allium porrum l. (liliaceae) bulbs are used as a folk remedy for the treatment of diabetes and they are also consumed as food in turkey. in the present study, the antidiabetic and antioxidant activities of the ethanol extracts of these plants were studied in normal and streptozotocin-induced diabetic rats for 5 days. all extracts were administrated orally to rats at the doses of 250 and 500 mg/kg. blood glu ...201020100559
first report on cydonia oblonga miller anticancer potential: differential antiproliferative effect against human kidney and colon cancer cells.the present study reports the phenolic profile and antiproliferative properties of quince (cydonia oblonga miller) leaf and fruit (pulp, peel, and seed) against human kidney and colon cancer cells. the phenolic profiles of quince methanolic extracts were determined by high-performance liquid chromatography (hplc)/diode array detector (dad). 5-o-caffeoylquinic acid was always one of the two major phenolic compounds present in all extracts, except for seed. our results revealed that quince leaf an ...201020192210
immunomodulatory properties of a lemon-quince preparation (gencydo®) as an indicator of anti-allergic potency.gencydo®, a combination of lemon (citrus limon) juice and aqueous quince (cydonia oblonga) extract has been used traditionally in anthroposophical medicine for treating patients with allergic rhinitis or asthma. because there are no reports about the mode of action, we investigated the anti-allergic effects of this preparation in vitro by using cell lines and primary cells in various biological and immunological endpoints.201121256726
inhibitory effect of hot-water extract of quince (cydonia oblonga) on immunoglobulin e-dependent late-phase immune reactions of mast cells.we evaluated the effect of a crude hot-water extract (hw) of quince (cydonia oblonga miller) fruit on immunoglobulin e (ige)-dependent late-phase immune reactions of mast cells using in vitro system. mast cell-like rbl-2h3 cells were treated with quince hw and late-phase reaction was then induced by stimulation with ige + antigen. quince hw reduced the elevation of interleukin-13 and tumor necrosis factor-a expression level. furthermore, quince hw suppressed these cytokine expressions of mouse b ...201121264509
oxidative stress responses and root lignification induced by fe deficiency conditions in pear and quince genotypes.we analysed pyrus communis cv. conference and cydonia oblonga ba29, differently tolerant to lime-induced chlorosis, to identify the key mechanisms involved in their different performance under fe deficiency induced by the absence of fe (-fe) or by the presence of bicarbonate (+febic). under our experimental conditions, a decrease in root elongation was observed in ba29 under bicarbonate supply. superoxide dismutase (sod) and peroxidase (pod) activities were analysed and the relative isoforms wer ...201121389006
oviposition site preferences and performance in natural resources in the human commensals drosophila melanogaster and d. simulans.the choice of egg laying site and progeny's performance in a rearing site are important components of habitat selection. despite the huge amount of genetic, morphological, behavioral and physiological data regarding drosophila melanogaster meigen and d. simulans sturtevant, oviposition site preferences remain poorly known. we investigated resource preference (acceptance and choice) and performance (measured as larval viability, developmental time and wing size) in vitis vinifera linneo (grape) a ...201121540639
In Vitro Antiallergic Effects of Aqueous Fermented Preparations from Citrus and Cydonia fruits.This study aimed to investigate the immunomodulatory and antiallergic properties of preparations from lemon, CITRUS MEDICA L. ( CITRUS), and quince, CYDONIA OBLONGA Mill. ( CYDONIA), which are used in pharmaceutical products to treat patients suffering from allergic disorders. Preparations were analyzed with respect to their impact on the degranulation capacity from basophilic cells as well as mediator release from activated human mast cells IN VITRO, including IL-8 and TNF- a secretion. The ...201122193979
quince (cydonia oblonga miller) peel polyphenols modulate lps-induced inflammation in human thp-1-derived macrophages through nf-κb, p38mapk and akt inhibition.chronic inflammation is a hallmark of several pathologies, such as rheumatoid arthritis, gastritis, inflammatory bowel disease, atherosclerosis and cancer. a wide range of anti-inflammatory chemicals have been used to treat such diseases while presenting high toxicity and numerous side effects. here, we report the anti-inflammatory effect of a non-toxic, cost-effective natural agent, polyphenolic extract from the tunisian quince cydonia oblonga miller. lipopolysaccharide (lps) treatment of human ...201222252293
identification and characterization of an isolate of apple green crinkle associated virus involved in a severe disease of quince (cydonia oblonga, mill.).a quince tree showing severe symptoms of a previously undescribed viral disease occurring in northern apulia (italy) was analysed using high-throughput sequencing of small rna libraries, leading to the identification of a new strain of apple green crinkle associated virus (isolate agcav-cyd) showing peculiar traits. rt-pcr with specific primers detected agcav-cyd in consistent association with symptoms in the surveyed orchards. molecular characterization of the reconstructed genome, together wit ...201727709400
use of atomic absorption spectrometry in assessment of biomonitor plants for lead, cadmium and copper pollution.eleven plant species were collected from the vicinity of lead-battery plant in the city of gaziantep, turkey. lead, cadmium and copper concentrations in the soil and leaves of plants were determined by atomic absorption spectrometry. lead, cd and cu concentrations in the soil samples taken from battery area were found to be in the ranges of 304-602, 0.4-0.44 and 31-37 mg x kg(-1), respectively. significantly increased lead concentration up to 2 750 mg x kg(-1) was found in the leaves of eleagnus ...201222497165
chinese vegetative materia medica in a venereological treatise by jean astruc from 1740.historical medical sources can be still queried for forgotten cures and remedies. traditional chinese medicine has dealt with lues venerea (syphilis) since the five dynasties period (10th century). chinese indigenous materia medica and remedies recorded, studied or imported by the europeans can reveal known or quite unknown medicinal plants. the studied jean astruc's work is a published ethnopharmacological survey carried out in beijing in the 1730s and it deserves a modern interpretation.201627132716
uptake of sodium in quince, sugar beet, and wheat protoplasts determined by the fluorescent sodium-binding dye benzofuran isophthalate.the uptake of sodium into protoplasts of quince (cydonia oblonga mill, clone ba29), sugar beet (beta vulgaris l. cv. monohill), and wheat (triticum aestivum l. cv. kadett) was determined by use of the acetoxy methyl ester of the fluorescent sodium-binding benzofuran isopthalate (sbfi-am). in the presence of 1 mm cacl2, little sodium was taken up in the cytosol of quince mesophyll cells compared to cytosols of sugar beet and wheat. upon addition of 40 mm nacl, approximately the same amount of sod ...200515900884
laūq: a sustained-release dosage form for respiratory disorders in traditional persian medicine.laūq is a pharmaceutical dosage form that had been mainly used for the treatment of various respiratory disorders in traditional persian medicine. it is important from 2 aspects: a dosage form with efficient and optimum delivery of drugs to the respiratory tract and biological effects of its ingredients. natural medicine in laūq has been demonstrated to act in respiratory disorders by their antitussive, antiallergic, anti-inflammatory, antioxidant, spasmolytic, and antibacterial activities. some ...201626008751
medicinal plants for management of gastroesophageal reflux disease: a review of animal and human studies.gastroesophageal reflux disease (gerd) is a prevalent gastrointestinal disease that causes troublesome symptoms and/or complications. the major therapeutic strategy for gerd focuses mainly on symptom alleviation using proton pump inhibitors (ppis), which does not produce a perfect response in all patients. an approach with new therapeutic agents for gerd seems to be essential. the aim of this study was to review animal and human studies investigating the effect of medicinal plants in gerd as wel ...201727996295
scientific evaluation of medicinal plants used for the treatment of abnormal uterine bleeding by avicenna.abnormal uterine bleeding (aub) is one of the prevalent gynecological disorders that cause considerable morbidity and management of that plays an important role in protecting women's health. this review focuses on medicinal plants mentioned by avicenna, a great iranian philosopher and physician (a.d. 980-1037), in his book canon for treatment of aub.201525637505
efficacy of a nasal spray from citrus limon and cydonia oblonga for the treatment of hay fever symptoms-a randomized, placebo controlled cross-over study.nasal spray from lemon and quince (lqns) is used to treat hay fever symptoms and has been shown to inhibit histamine release from mast cells in vitro. forty-three patients with grass pollen allergy (gpa) were randomized to be treated either with placebo or lqns for one week, respectively, in a cross-over study. at baseline and after the respective treatments patients were provoked with grass pollen allergen. outcome parameters were nasal flow measured with rhinomanometry (primary), a nasal sympt ...201627282490
[the effect of a nasal spray consisting of a standardized mixture of citrus limon (succus) and an aqueous extract of cydonia oblongata (fructus) on nasal mucociliary clearance].in a three-way-crossover study in 18 healthy male and female subjects aged from 20 to 49 years the influence of a 1% and 3% solution of a standardized composition of citrus limon, succus, and extract from cydonia oblonga, fructus (gencydo) on the intranasal mucociliar clearance was investigated after multiple administration. the ph of the solution was about ph 2.3-3.2. the dose regimen consisted of 20 puffs (0.13 ml per puff) in each nostril within 24 h, which was by factor 3-10 higher than the ...200010683714
endocrine disruption, oxidative stress, and testicular damage induced by 4-nonylphenol in clarias gariepinus: the protective role of cydonia oblonga.exposure to xenoestrogens like 4-nonylphenol (np) is recognized by disrupting endocrine functions and causes reproductive dysfunction in male fish. the present study aimed at investigating the 4-nonylphenol propensity to induce oxidative stress and hormonal disturbances in male catfish and at studying the protective role of quince (cydonia oblonga). to fulfill this aim, catfish clarias gariepinus were exposed to pure 100 μg/l 4-np and to quince the leaf extract added to 4-np, both for 15 days. t ...201728285354
induction of apoptosis and dna damage by 4-nonylphenol in african catfish (clarias gariepinus) and the antioxidant role of cydonia oblonga.in this study, we assessed the toxic effects of sub lethal concentration (0.1mgl(-1)) 4-nonylphenol (4-np) on serum biochemical parameters, liver lipid peroxidation (lpo) and antioxidant enzymes of the african catfish clarias gariepinus for 14 days and the ability of the quince leaf extract to alleviate the effects of (4-np). fish were categorized into four groups: control, exposure to 0.1mgl(-1) 4-np, exposure to 0.1mgl(-1) 4-np with quince leaf extract (10ml/30l water), and exposure to 0.1mgl( ...201728113117
use of hematological parameters to assess the efficiency of quince (cydonia oblonga miller) leaf extract in alleviation of the effect of ultraviolet--a radiation on african catfish clarias gariepinus (burchell, 1822).the present study aimed to elucidate the negative impacts of uva on some biochemical and hematological variables of the economically important african catfish, clarias gariepinus and investigates the putative role of quince (cydonia oblonga miller) leaf extract in protection and/or alleviation of such negative impacts. changes in the hematological and blood biochemical values often reflect alteration of physiological state. blood parameters can be useful for the measurement of physiological dist ...201020206545
mitochondria as a target for the cardioprotective effects of cydonia oblonga mill. and ficus carica l. in doxorubicin-induced cardiotoxicity.quince (cydonia oblonga mill.) and fig (ficus carica l.) exhibit a broad spectrum of pharmacological activities. regarding the cardiotoxic effect of doxorubicin (dox) is mediated mainly through mitochondrial oxidative stress and dysfunction; the present study evaluated the cardioprotective effects of the aqueous extracts of cydonia oblonga mill. fruit (aco) and ficus carica l. fruit (afc) against dox-induced cardiotoxicity. cardiomyocytes toxicity was induced in male sprague dawley rats by intra ...201728320040
effect of the topical application of an ethanol extract of quince seeds on the development of atopic dermatitis-like symptoms in nc/nga mice.quince (cydonia oblonga miller) is a deciduous shrub belonging to the rosaceae family. quince seed extract has long been used as a cosmetic ingredient for its moisturizing effect. however, little is known about whether quince seed extract has therapeutic effects on keratinocyte-associated skin inflammation.201728137259
cydonia oblonga m., a medicinal plant rich in phytonutrients for pharmaceuticals.cydonia oblonga m. is a medicinal plant of family rosaceae which is used to prevent or treat several ailments such as cancer, diabetes, hepatitis, ulcer, respiratory, and urinary infections, etc. cydonia oblonga commonly known as quince is rich in useful secondary metabolites such as phenolics, steroids, flavonoids, terpenoids, tannins, sugars, organic acids, and glycosides. a wide range of pharmacological activities like antioxidant, antibacterial, antifungal, anti-inflammatory, hepatoprotectiv ...201627445806
news from tartary: an ethnopharmacological approach to drug and therapeutic discovery.ethnopharmacology aims to identify new therapeutic agents based on their traditional use. it begins by the identification of disease states, and of the traditional therapies for these, most commonly herbals. herbals of interest are selected from ethnopharmacological surveys, and tested on experimental models of the diseases of interest. once the activity of the traditional remedy is demonstrated, including dose-dependence, if possible comparatively to reference medications, the active ingredient ...201727297624
antioxidant bioactive compounds changes in fruit of quince genotypes over cold storage.quince fruit has many benefits to human health and is excellent source of bioactive compounds. the fruit of 15 quince genotypes stored at 2 °c for 5 mo to study fruit quality changes during cold storage. fruit were sampled monthly and stored at 20 °c for 24 h. fruit ascorbic acid (aa), total phenol (tp), and total flavonoid (tf) concentrations, total antioxidant activity (taa), flesh browning (fb) incidence, polyphenol oxidase (ppo), peroxidase (pox), and superoxide dismutase (sod) activities we ...201627273124
[anti-hypertensive effect of total flavonoids of cydonia oblonga leaves and its mechanism based on anti-inflammatory function].to study the anti-hypertensive effect of total flavonoids of cydonia oblonga leaves in spontaneously hypertensive rats, then to preliminarily investigate the mechanism of action based on anti-inflammatory function.201527254930
quince peel polyphenolic extract blocks human colon adenocarcinoma ls174 cell growth and potentiates 5-fluorouracil efficacy.development of alternative cancer-specific drugs would be of paramount importance to overcome toxicity toward normal tissues and tumor resistance. here, we investigated the potential anti-tumoral effect of peel (peph) and pulp polyphenolic extracts from the tunisian quince cydonia oblonga miller on both no-tumorigenic cells nih 3t3 fibroblasts and hek 293 cells and human colon adenocarcinoma ls174 cells.201526839513
hypolipidemic, hepatoprotective and renoprotective effects of cydonia oblonga mill. fruit in streptozotocin-induced diabetic rats.diabetes mellitus is associated with complications in several different systems of the body, and the incidence of diabetes is rapidly increasing worldwide. the objective of the present study was to evaluate the effect of aqueous extract of cydonia oblonga mill. fruit on lipid profile and some biochemical parameters in streptozotocin-induced diabetic rats. the extract showed anti hyper lipidemic activity as evidenced by significant decreases in serum triglyceride, total cholesterol, and low densi ...201526664388
effects of quince syrup on clinical symptoms of children with symptomatic gastroesophageal reflux disease: a double-blind randomized controlled clinical trial.the aim of this study was to evaluate the efficacy of quince syrup in pediatrics with symptomatic gastroesophageal reflux disease (gerd).201526573454
effects of cydonia oblonga miller leaf and fruit flavonoids on blood lipids and anti-oxydant potential in hyperlipidemia rats.to study the effects of cydonia oblonga miller (com) total flavonoids (tf) from leaves and fruit on the blood lipid and antioxidant potentials using hyperlipidaemic rat models.201525934516
influence of rootstocks on growth, yield, fruit quality and leaf mineral element contents of pear cv. 'santa maria' in semi-arid conditions.rootstocks play an essential role to determining orchard performance of fruit trees. pyrus communis and cydonia oblonga are widely used rootstocks for european pear cultivars. the lack of rootstocks adapted to different soil conditions and different grafted cultivars is widely acknowledged in pear culture. cydonia rootstocks (clonal) and pyrus rootstocks (seedling or clonal) have their advantages and disadvantages. in each case, site-specific environmental characteristics, specific cultivar resp ...201425723734
botanicals: an alternative remedy to radiotherapy-induced dysuria.everyday, many patients get radiotherapy for prostatic, rectal, uterine cervix and other pelvic organs cancer. dysuria is common in pelvic, especially prostate radiotherapy, but there is not any established and confirmed treatment for this therapeutic side effect. therefore, an alternative therapeutic method, using herbal preparation, may be an effective solution. this study seeks a defensible suggestion in iranian traditional medicine (itm). in itm, a few medicinal herbs such as plantago psylli ...201525637157
oxidative stress associated with rootstock-scion interactions in pear/quince combinations during early stages of graft development.exposing a plant to stress situations, such as grafting, generally triggers antioxidant defense systems. in fruit tree grafting, quince (cydonia oblonga) is widely used as a rootstock for pear (pyrus communis l.), but several economically important pear cultivars are incompatible with available quince rootstocks. in this study, grafts were established using an in vitro callus graft system mimicking the events taking place in fruit trees. in vitro grown callus from pear [p. communis l. cv. 'confe ...201525543953
technological aspects as the main impact on quality of quince liquors.phytochemical profiles of 24 quince liquors were studied as the combination of technologically variant. liquors were obtained after macerating quinces from three varieties (vranja, alm3 and zm2), with or without skin, at two ratios of quince:ethanol (50:50 and 25:75), and at two alcohol content (60% and 30%). polyphenols were identified by lc-pda-qtof/ms and quantified by uplc-pda and uplc-fl. a total of 18 polyphenolic compounds were identified and classified as 5 flavan-3-ols, 5 phenolic acids ...201525149002
cryopreservation of quince (cydonia oblonga mill.).quince (cydonia oblonga mill.) has great potential for utilisation in pharmaceutical and food industries.201424997836
drying method effects on the antioxidant activity of quince (cydonia oblonga miller) tea.quince has many health benefits. dried quince has been used as a tea for centuries. the aim of this study was to investigate the influences of two drying methods on the antioxidant activity of the quince.201424876308
effects of cydonia oblonga miller extracts on blood hemostasis, coagulation and fibrinolysis in mice, and experimental thrombosis in rats.cydonia oblonga miller (com) is traditionally used in uyghur medicine for the prevention of cardiovascular disease. the present study is designed to explore the effects of com extracts on models and markers of thrombosis and related biomarkers.201424704668
effect of cydonia oblonga mill. leaf extracts or captopril on blood pressure and related biomarkers in renal hypertensive rats.cydonia oblonga mill. (com) is used in traditional uyghur medicine to treat or prevent cardiovascular disease. in a previous study com leaf extracts were found to be active in renal hypertensive rats (rhr). the present study tests the dose-dependence of the effect of ethanol leaf extracts on hypertension and on biomarkers associated with blood pressure control, such as angiotensin-ii (aii), plasma renin activity (pra), apelin-12 (a), endothelin (et) and nitric oxide (no), compared to captopril.201424661965
effect of hydroalcoholic extract of cydonia oblonga miller (quince) on sexual behaviour of wistar rats.cydonia oblonga miller (quince) is regarded as a potent libido invigorator in tib-e-nabvi and unani system of medicine. this study was carried out to evaluate the aphrodisiac activity of the hydroalcoholic extract of the fruits of cydonia oblonga miller (quince) in wistar rats. the extract was administered orally by gavage in the dose of 500 mg/kg and 800 mg/kg body weight per day as a single dose for 28 days. the observed parameters were mounting frequency, assessment of mating performance, and ...201424648836
the enzymatic decolorization of textile dyes by the immobilized polyphenol oxidase from quince leaves.water pollution due to release of industrial wastewater has already become a serious problem in almost every industry using dyes to color its products. in this work, polyphenol oxidase enzyme from quince (cydonia oblonga) leaves immobilized on calcium alginate beads was used for the successful and effective decolorization of textile industrial effluent. polyphenol oxidase (ppo) enzyme was extracted from quince (cydonia oblonga) leaves and immobilized on calcium alginate beads. the kinetic proper ...201424587743
genetic variation among quince (cydonia oblonga mill.) genotypes sampled from the coruh valley in turkey.turkey has very rich quince genetic resources, and the country currently dominates world quince production. in particular, the northeastern part of the country has notable cydonia oblonga mill. germplasm. authenticating the identity of germplasm resources of c. oblonga mill. would be of great value for breeding practices. in the present study, genetic variations of 14 c. oblonga mill. genotypes sampled from the coruh valley of turkey were investigated. ten random primers generated 53 dna markers ...201424535871
effect of cydonia oblonga mill. fruit and leaf extracts on blood pressure and blood rheology in renal hypertensive rats.quince, cydonia oblonga mill. (com), is used in traditional uyghur medicine to treat or prevent cardiovascular diseases. uyghur people have greater longevity and lower blood pressure than other central asian populations. we therefore tested com fruit and leaf extracts on blood pressure and rheology in renal hypertensive rats (rhr).201424472663
antioxidant property and storage stability of quince juice phenolic compounds.the aim of this study was to characterise, in depth, 11 quince cultivars to provide data for their industrial processing into high-quality juices. polyphenolic composition analyses (identification and quantification), soluble fraction of procyanidins, antioxidant capacity assays and cluster analysis were measured. a total of 19 kinds of polyphenolic compounds were the following in the juices: before and after 6 month of storage time at 4 and 30 °c. large variations in polyphenolic compounds cont ...201424444935
effect of cydonia oblonga mill. leaf extract on serum lipids and liver function in a rat model of hyperlipidaemia.cydonia oblonga mill. leaves are traditionally used in uyghur medicine to treat or prevent cardiovascular disease. beyond a demonstrated effect on thrombosis, we tested it for an effect on dyslipidemia, in a rat model of hyperlipidemia.201424342780
characterization of anatolian traditional quince cultivars, based on microsatellite markers.we conducted simple sequence repeat (ssr) analyses of 15 traditional quince (cydonia oblonga) cultivars from anatolian gene sources for molecular characterization and investigation of genetic relationships. three pear and two apple cultivars were used as references for ssr locus data analysis and to determine allele profiles between species. eight ssr loci that were developed from apple and pear were used, and a total of 44 alleles were found among quince cultivars. the ch01f02 locus was found t ...201324301958
pectin extraction from quince (cydonia oblonga) pomace applying alternative methods: effect of process variables and preliminary optimization.the objectives of this study were to introduce alternative methods in the process of pectin extraction from quince pomace, to determine the effect of selected process variables (factors) on the obtained pectin, and to perform a preliminary optimization of the process. a fractional factorial experimental design was applied, where the factors considered were six: quince pomace pretreatment (washing vs blanching), drying method (hot air vs lpssd), acid extraction conditions (ph, temperature, and ti ...201423733815
effect of a peat humic acid on morphogenesis in leaf explants of pyrus communis and cydonia oblonga . metabolomic analysis at an early stage of regeneration.plant regeneration is a critical step in most in vitro breeding techniques. this paper studies the effects of a low-molecular-weight humic acid (ha) on morphogenesis from pear and quince leaf explants. variable ha amounts [0 (control), 1, 5, 10, and 20 mg c l(-1)] were added to the regeneration media. a dose-response effect was observed in pear for root and shoot production; it was improved at ha 1 mg c l(-1) and considerably reduced at the highest amounts. ha was, instead, ineffective in quince ...201323627499
polyphenolic composition, antioxidant activity, and polyphenol oxidase (ppo) activity of quince (cydonia oblonga miller) varieties.phytochemical profiles (phenolic compounds, l-ascorbic acid, antioxidant and ppo activities) of 13 different quince varieties and 5 genotypes were studied. polyphenols were identified by lc-pda-qtof/ms and quantified by uplc-pda and uplc-fl. a total of 26 polyphenolic compounds found in quince tissues were identified and presented: 9 flavan-3-ols ((-)-epicatechin, procyanidin b2, 3 procyanidin dimers and trimers, and 1 tetramer); 8 hydroxycinnamates, derivatives of caffeoylquinic and coumaroylqu ...201323461298
a study of the effects of cydonia oblonga miller (quince) on tnbs-induced ulcerative colitis in rats.cydonia oblonga miller (quince) from rosaceae family is a fruit tree cultivated in many countries mainly in iran. this study was carried out to investigate the effect of quince juice (qj) and quince hydroalcoholic extract (qhe) on ulcerative colitis (uc) induced by tnbs (trinitrobenzene sulfonic acid) in rats. rats were grouped (n=6) and fasted for 36 h before colitis induction. tnbs was instilled into the colon with a hydroalcoholic carrier and then treatments were made for 5 days starting 6 h ...201223181087
antioxidant properties and cytotoxic effects on human cancer cell lines of aqueous fermented and lipophilic quince (cydonia oblonga mill.) preparations.in the course of a screening program on quince phytochemicals, two complex preparations were in the focus of the present study, i.e., a lipophilic quince wax extract (qwe) and an aqueous fermented one (qafe). while the phytochemical composition has been described earlier, the intention of the current investigation was to complement these data with an extensive antioxidant screening of these preparations including their radical scavenging and reductive power as well as their antilipoperoxidative ...201223034449
identification and quantitation of carotenoids and tocopherols in seed oils recovered from different rosaceae species.seed oils recovered from rosaceae species such as dessert and cider apples (malus domestica borkh.), quince (cydonia oblonga mill.), and rose hip (rosa canina l.) were analyzed for their tocopherol and carotenoid contents using hplc-dad-ms(n) following saponification. qualitative and quantitative tocopherol and carotenoid compositions significantly differed, not only among the different genera but also among cultivars of one species. in particular, seed oils of cider apples were shown to contain ...201223020156
comparison of supercritical fluid extraction and ultrasound-assisted extraction of fatty acids from quince (cydonia oblonga miller) seed using response surface methodology and central composite design.fatty acids of cydonia oblonga miller cultivated in iran were obtained by supercritical (carbon dioxide) extraction and ultrasound-assisted extraction methods. the oils were analyzed by capillary gas chromatography using mass spectrometric detections. the compounds were identified according to their retention indices and mass spectra (ei, 70ev). the experimental parameters of sfe such as pressure, temperature, modifier volume, static and dynamic extraction time were optimized using a central com ...201222824221
activity, polypeptide and gene identification of thylakoid ndh complex in trees: potential physiological relevance of fluorescence assays.three evergreen (laurus nobilis, viburnum tinus and thuja plicata) and two autumnal abscission deciduous trees (cydonia oblonga and prunus domestica) have been investigated for the presence (zymogram and immunodetection) and functionality (post-illumination chlorophyll fluorescence) of the thylakoid ndh complex. the presence of encoding ndh genes has also been investigated in t. plicata. western assays allowed tentative identification of zymogram nadh dehydrogenase bands corresponding to the ndh ...201222324908
the effect of quince leaf (cydonia oblonga miller) decoction on testes in hypercholesterolemic rabbits: a pilot study.current medical literature lacks any evidence of the protective effects of quince leaf on testes. therefore, the aim of the present study was to assess the effect of quince (cydonia oblonga miller) leaf decoction on testicular injury and impaired spermatogenesis induced by hypercholesterolemia in rabbits. eleven mature new zealand white male rabbits were randomly divided into three groups: group 1 (hypercholesterolemia, n=3), group 2 (hypercholesterolemia plus quince treatment, n=6), and group 3 ...201324146451
assessing molecular and morpho-agronomical diversity and identification of issr markers associated with fruit traits in quince (cydonia oblonga).quince is a deciduous tree known to the countries around the mediterranean since antiquity. nowadays, quince is used as an ornamental plant, and as a rootstock for pear trees, with its fruit being appreciated mainly for production of jam and sweets rather than for raw consumption. quince leaves contain compounds with antioxidant, antimicrobial and anticancerous properties that have been the focus of recent research on pharmaceutical and medical uses as well as for food preservatives. an orchard ...201122095599
erratum to: inhibitory effect of hot-water extract of quince (cydonia oblonga) on immunoglobulin e-dependent late-phase immune reactions of mast cells. 201121779904
oxidative stress and senescence-like status of pear calli co-cultured on suspensions of incompatible quince microcalli.this work presents a simple in vitro system to study physiological, biochemical and molecular changes occurring in a pear callus (pyrus communis l., cv. beurré bosc) grown in close proximity to spatially separated undifferentiated homologous (pear) or heterologous (quince; cydonia oblonga mill., east malling clone c) cells in its neighboring environment. after a 7-day co-culture period, the presence of heterologous cells produced negative effects on the pear callus, whose relative weight increas ...201020190345
concentration dependent effects of commonly used pesticides on activation versus inhibition of the quince (cydonia oblonga) polyphenol oxidase.polyphenol oxidase (ppo) catalyzes the oxidation of o-diphenols to their respective quinones which undergo autopolymerization and form dark pigments. the interaction of ppo with various substrates and effectors remains the focus of intensive investigations due to the enzyme's key role in pigments biosynthesis including animal melanogenesis and fruit/fungi enzymatic browning. in this study, the effect of a range of commonly used pesticides on the enzyme activity has been evaluated using the purif ...201020060877
sodium induces simultaneous changes in cytosolic calcium and ph in salt-tolerant quince protoplasts.previous experiments with salt-resistant quince ba29 (cydonia oblonga cv. mill.) have shown that this cultivar takes up sodium transiently into the cytosol of shoot protoplasts only in the absence of calcium chloride, or at <1mm calcium chloride. addition of nacl > or =100mm to single protoplasts from in vitro-cultivated quince in the presence of 1.0mm calcium induced instant changes in the cytosolic concentrations of calcium and protons. these changes were investigated by use of tetra [acetoxym ...200919556023
differential responses in pear and quince genotypes induced by fe deficiency and bicarbonate.most of the studies carried out on fe deficiency condition in arboreous plants have been performed, with the exception of those carried out on plants grown in the field, in hydroponic culture utilizing a total iron depletion growth condition. this can cause great stress to plants. by introducing fe deficiency induced by the presence of bicarbonate, we found significant differences between pyrus communis l. cv. conference and cydonia oblonga mill. ba29 and ma clones, characterized by different le ...200919269060
organic acids composition of cydonia oblonga miller leaf.organic acid profiles of 36 cydonia oblonga miller leaf samples, from three different geographical origins of northern (bragança and carrazeda de ansiães) and central portugal (covilhã), harvested in three collection months (june, august and october of 2006), were determined by hplc/uv (214nm). quince leaves presented a common organic acid profile, composed of six constituents: oxalic, citric, malic, quinic, shikimic and fumaric acids. c. oblonga leaves total organic acid content varied from 1.6 ...200826047441
natural wax constituents of a supercritical fluid co(2) extract from quince (cydonia oblonga mill.) pomace.the chemical constituents of a lipophilic extract from quince (cydonia oblonga mill.), obtained by supercritical fluid co(2) extraction of the dried fruit pomace were investigated. solvent partition of quince wax with n-hexane or acetone yielded an insoluble (crystalline) and a soluble (oily) fraction. both fractions were analyzed separately using gas chromatography/mass spectrometry (gc/ms). the insoluble fraction consisted of saturated n-aldehydes, n-alcohols and free n-alkanoic acids of carbo ...200818418588
phenolic profile of cydonia oblonga miller leaves.cydonia oblonga miller leaves phenolic compounds were analyzed by reversed-phase hplc/dad and hplc/uv. qualitative and quantitative analysis of phenolics were carried out in a total of 36 samples of quince leaves from three different geographical origins of northern (bragança and carrazeda de ansiães) and central portugal (covilhã) and three collection months (june, august, and october of 2006). these leaves presented a common phenolic profile composed by nine compounds: 3- o-, 4- o- and 5- o-ca ...200717711340
antimicrobial activity of tunisian quince (cydonia oblonga miller) pulp and peel polyphenolic extracts.quince (cydonia oblonga miller) fruit aqueous acetone extracts were evaluated. high-performance liquid chromatography-diode array detection and electrospray ionization-mass spectrometry were used for the identification and quantification of the phenolic compounds. the total phenolic content of the pulp and peel parts ranged from 37 to 47 and 105 to 157 mg/100 g of fresh weight, respectively. chlorogenic acid (5-o-caffeoylquinic acid) was the most abundant phenolic compound in the pulp (37%), whe ...200717263500
differentiation and functional connection of vascular elements in compatible and incompatible pear/quince internode micrografts.micrografts of internodes excised from in vitro grown pear plants (pyrus communis l. cv. 'bosc' (b) and cv. 'butirra hardy' (bh)) and quince (cydonia oblonga mill. east malling clone c (emc)), were cultured aseptically to test the effectiveness of their functional vascular reconnection in relation to incompatibility-compatibility relationships that these genotypes exhibit in the field. the incompatible heterograft (b/emc) showed a marked delay in internode cohesion compared with the autografts ( ...200516105809
phenolic profile, antioxidant property, and anti-influenza viral activity of chinese quince (pseudocydonia sinensis schneid.), quince (cydonia oblonga mill.), and apple (malus domestica mill.) fruits.to evaluate the phenolic extracts of chinese quince, quince, and apple fruits, their phenolic profiles, antioxidant properties, and anti-influenza viral activities were investigated. chinese quince had the largest amount of phenolics consisting mainly of high polymeric procyanidins. quince had considerable amounts of hydroxycinnamic derivatives mainly composed of 3-caffeoylquinic acid and 5-caffeoylquinic acid and polymeric procyanidins. apple (cv. fuji) had the lowest amount of phenolics, mainl ...200515713000
composition of quince (cydonia oblonga miller) seeds: phenolics, organic acids and free amino acids.phenolic compounds, organic acids and free amino acids of quince seeds were determined by hplc/dad, hplc/uv and gc/fid, respectively. quince seeds presented a phenolic profile composed of 3-o-caffeoylquinic, 4-o-caffeoylquinic, 5-o-caffeoylquinic and 3,5-dicaffeoylquinic acids, lucenin-2, vicenin-2, stellarin-2, isoschaftoside, schaftoside, 6-c-pentosyl-8-c-glucosyl chrysoeriol and 6-c-glucosyl-8-c-pentosyl chrysoeriol. six identified organic acids constituted the organic acid profile of quince ...200515702641
quince (cydonia oblonga miller) fruit characterization using principal component analysis.this paper presents a large amount of data on the composition of quince fruit with regard to phenolic compounds, organic acids, and free amino acids. subsequently, principal component analysis (pca) is carried out to characterize this fruit. the main purposes of this study were (i) the clarification of the interactions among three factors-quince fruit part, geographical origin of the fruits, and harvesting year-and the phenolic, organic acid, and free amino acid profiles; (ii) the classification ...200515631517
quince (cydonia oblonga miller) fruit (pulp, peel, and seed) and jam: antioxidant activity.to study the antioxidant activity of quince fruit (pulp, peel, and seed) and jam, methanolic extracts were prepared. each extract was fractionated into a phenolic fraction and an organic acid fraction and was analyzed by high-performance liquid chromatography (hplc)/diode array detection and hplc/uv, respectively. antiradical activities of the extracts and fractions were evaluated by a microassay using 1,1'-diphenyl-2-picrylhydrazyl. the phenolic fraction always exhibited a stronger antioxidant ...200415264903
free amino acid composition of quince (cydonia oblonga miller) fruit (pulp and peel) and jam.twenty-one free amino acids present in several samples of quince fruit (pulp and peel) and quince jam (homemade and industrially manufactured) were analyzed by gc/fid. the analyses showed some differences between quince pulps and peels. generally, the highest content in total free amino acids and in glycine was found in peels. as a general rule, the three major free amino acids detected in pulps were aspartic acid, asparagine, and hydroxyproline. for quince peels, usually, the three most abundan ...200414995121
approach to the study of c-glycosyl flavones by ion trap hplc-pad-esi/ms/ms: application to seeds of quince (cydonia oblonga).ion trap hplc-pad-esi/ms/ms has been used to study c-glycosyl flavones in quince seeds. comparative analysis of the ions [(m-h)-60]-, [(m-h)-90]- and [(m-h)-120]- from 6-c- and 8-c-glycosyl flavone isomers, together with their respective retention times, allowed deductions to be made about the nature of the sugar units and the positions of c-glycosylation. vicenin-2 (6,8-di-c-glucosyl apigenin), lucenin-2 (6,8-di-c-glucosyl luteolin), stellarin-2 (6,8-di-c-glucosyl chrysoeriol), isoschaftoside ( ...200614667061
localized graft incompatibility in pear/quince (pyrus communis/cydonia oblonga) combinations: multivariate analysis of histological data from 5-month-old grafts.to characterize the structural events associated with incompatibility of graft development, we conducted a histological study of compatible and incompatible pear/pear and pear/quince grafts that had been grown for five months in a greenhouse. multivariate analysis of histological data describing the structure of the graft union allowed us to discriminate between compatible and incompatible combinations before either macroscopic examination or qualitative microscopic examination differences betwe ...199912651320
phenolic profile of quince fruit (cydonia oblonga miller) (pulp and peel).qualitative and quantitative analyses of phenolic compounds were carried out on quince fruit samples from seven different geographical origins in portugal. for each origin, both pulp and peel were analyzed by reversed-phase hplc-dad and hplc-dad/ms. the results revealed differences between the phenolic profiles of pulps and peels in all studied cases. the pulps contained mainly caffeoylquinic acids (3-, 4-, and 5-o-caffeoylquinic acids and 3,5-dicaffeoylquinic acid) and one quercetin glycoside, ...200212137485
synthesis of the glycosidic precursor of isomeric marmelo lactones, volatile components of the quince fruit, cydonia oblonga.the glucosidic precursor of marmelo lactones was synthesized by employing a common intermediate which had been used for the synthesis of the glucosidic precursor of marmelo oxides. the synthesis was performed by modifying the former procedure. monochloroacetyl was adopted to protect both the glucose and aglycon hydroxyl groups for selective transesterification in the presence of the glycosyl ester. glycosylation of the aglycon carboxyl group with 1-alpha-bromopermonochloroacetylglucose and final ...200212036045
isolation of two new ionone glucosides from quince (cydonia oblonga mill.) leaves.the 9-o-beta-d-glucopyranosides of (6r)-3-oxo-4-hydroxy-7,8-dihydro-alpha-ionol 1 and 3-oxo-5,6-epoxy-beta-ionol 2 were isolated from quince leaves. the glycosidic extract was obtained by xad-2 adsorption and meoh elution. after dccc separation and flash chromatography, purification by high performance liquid chromatography was carried out. the novel quince leaf constituents were characterized as peracetates 1a and 2a.200211990428
study of the organic acids composition of quince (cydonia oblonga miller) fruit and jam.the organic acids present in several samples of quince fruit (pulp and peel) and quince jam (homemade and industrially manufactured) were analyzed by hplc. the sample preparation was simple, involving only extraction with methanol (40 degrees c) and filtration through a sep-pack c18 cartridge. the chromatographic separation was achieved using an ion exclusion column, nucleogel ion 300 oa (300 x 7.7 mm), in conjunction with a column heating device at 30 degrees c. an isocratic elution with h(2)so ...200211929290
partial purification and kinetic characterization of a carotenoid cleavage enzyme from quince fruit (cydonia oblonga).for the first time, a cytosolic carotenoid cleavage enzyme isolated from quince (cydonia oblonga) fruit is described. the enzyme was partially purified by using centrifugation, acetone precipitation, ultrafiltration (300 kd, 50 kd), isoelectric focusing (ph 3-10), and sodium dodecyl sulfate polyacrylamide gel electrophoresis (7.5%). in this way, an enzymatically active protein fraction was obtained that contained three similar proteins, all exhibiting molecular weights in the range of 20 kd. usi ...200211879057
plantlet regeneration from cultured leaves of cydonia oblonga l. (quince).adventitious shoots of cydonia oblonga quince a were obtained from leaves cultured on ms-n6 medium containing thidiazuron (tdz) and α-naphthaleneacetic acid (naa). the frequency of regeneration was high (78% of the cultured leaves with 3.2 shoots per regenerating leaf) at 32 μm tdz plus 0.3 μm naa on young leaves obtained from micropropagated shoots. shoots were rooted by culturing them first on medium containing 5 μm naa for one week and then on auxinfree medium for four weeks. the regeneration ...199124221587
liquid crystal-type assembly of native cellulose-glucuronoxylans extracted from plant cell wall.in numerous plant cell walls, the cellulose microfibrils are arranged in a helicoidal pattern which has been considered as an analog to a cholesteric order. here, we report on the spontaneous helicoidal organization which occurs in acellular conditions from aqueous suspensions of cellulose. the cellulosic mucilage of mature seeds of quince (cydonia oblonga l) was studied both in situ (pre-release mucilage) and after water extraction and in in vitro re-assembly (prolonged high speed ultracentrifu ...19911804508
a c13-norisoprenoid gentiobioside from quince fruit.the beta-d-gentiobioside [beta-d-glucopyranosyl(1----6)-beta-d-glucopyranoside] of 3-hydroxy-beta-ionol has been isolated and characterized in quince (cydonia oblonga) fruit through spectral and chemical studies. model experiments carried out with this new natural compound revealed its important role as precursor of a number of c13-norisoprenoid flavour compounds of quince essential oil.19911367795
phenolic profiles and metal ions analyses of pulp and peel of fruits and seeds of quince (cydonia oblonga mill.).six hydroxycinnamic acids were identified and determined quantitatively in methanol and acetone extracts from quince peel and pulp, namely 3-o-caffeoylquinic acid (3-cqa), 4-p-coumaroylquinic acid (hc1), 4-o-caffeoylquinic acid (4-cqa), 5-o-caffeoylquinic acid (5-cqa), derivative of p-coumaroylquinic acid (hc2) and 3,5-dicaffeoylquinic acid (3,5-dicqa). the most abundant hydroxycinnamic acid was 5-cqa (neochlorogenic acid) with 259.12-481.4mg/kgf.w. in peel and 97.33-217.36mg/kg in quince pulp. ...028490099
protective effect of two extracts of cydonia oblonga miller (quince) fruits on gastric ulcer induced by indomethacin in rats.in various studies, cydonia oblonga miller (quince) has been reported to have many properties such as antioxidant and anti-ulcerative effects. this study has aimed to investigate the protective effects of quince aqueous extract (qae) and quince hydroalcoholic extract (qhe) on gastric ulcer caused by indomethacin and the relevant macroscopic, histopathology, and biochemical factors in rats.201728900537
comparison of quince with vitamin b6 for treatment of nausea and vomiting in pregnancy: a randomised clinical trial.this trial was performed to compare quince (cydonia oblonga) fruit with vitamin b6 on 76 pregnant women with a gestational age of 6-14 weeks and mild-to-moderate nausea and vomiting (nvp) (40 in the quince and 36 in the b6 group). the 'pregnancy-unique quantification of emesis' (puqe-24) scale was used to examine the severity of nvp. the quince syrup (1 tablespoon/tds) or vitamin b6 tablets (20 mg/tds) were used as intervention for 1 week. the mean (±sd) age was 27.5 (±5.2) years. the score of t ...201728631509
a superporous and superabsorbent glucuronoxylan hydrogel from quince (cydonia oblanga): stimuli responsive swelling, on-off switching and drug release.current study was designed to investigate micromeritic properties, water absorption capacity, stimuli (ph, ethanol and saline) responsive swelling-deswelling (on-off switching) and controlled drug release from the polysaccharide glucuronoxylan isolated from the seeds of quince. the water retention capacity of quince hydrogel (qh) was found admirable. the hydrogel also exhibited privileged swelling in water and basic buffers (ph 6.8 and 7.4) while insignificant swelling in acidic buffer (ph 1.2). ...201727865952
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