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[a case of the imported plasmodium ovale malaria (author's transl)]. 1979112198
[plasmodium ovale malaria in france. probability of of genetic control of the incubation period (author's transl)].plasmodium ovale as the causative parasite in attacks of malaria is rare. nevertheless, the number of cases seen in france would seem to be on the increase. in 137 attacks of malaria collected between 1967 and 1978, plasmodium ovale was found on 13 occasions. the main characteristics of this form of malaria are, apart from its benign nature, the usual absence of any recurrence and a very variable incubation period, ranging from fifteen days to several months or even a year (with an average of 3. ...1979400010
plasmodium ovale malaria in canada following transfusion. 1977912619
plasmodium ovale in the highlands of irian jaya, indonesia. 19921449279
prophylaxis for malaria. helping world travelers come home healthy.malaria is largely preventable, so travelers should be taught general protective measures and given appropriate chemoprophylaxis before they leave on their trip. chloroquine phosphate (aralen) is still the drug of choice in locations where malaria remains chloroquine-sensitive. however, chloroquine-resistant areas infested with plasmodium falciparum are becoming more numerous. in such areas, mefloquine hydrochloride (lariam), doxycycline, or proguanil (paludrine) (obtainable outside the united s ...19921518752
spontaneous splenic rupture due to plasmodium ovale malaria. 19911681259
late plasmodium ovale malaria. 19911682724
recurrent plasmodium ovale infection from papua new guinea--chloroquine resistance or inadequate primaquine therapy? 19911753151
plasmodium ovale in indonesia.we report 34 infections by plasmodium ovale found among 15,806 blood film examinations taken between 1973 and 1989 from several sites in indonesia. twenty five of the p. ovale infections occurred in a single sample of 514 people living in owi, irian jaya. we detected five additional infections at 3 other sites in irian jaya. other infections by p. ovale occurred at two sites in west flores. another infection has already been reported from east timor. despite relatively frequent sampling of popul ...19902151542
[imported malaria at hospitals in bordeaux (france) in 1987 and 1988. report of 185 cases].100 cases of imported malaria were registered in hospitals of bordeaux in 1987 and 85 in 1988. origin of infestation is africa in 88 p.c. of the cases mainly from central africa (50 p.c.) in 1987 and western africa (67 p.c.) in 1988. the most frequent species was plasmodium falciparum 73 p.c. in 1987 and 82 p.c. in 1988. admitted cases in bordeaux were mainly french (81 p.c.) with a significant male prevailing and young adults. mean age was 29 for europeans and 19 for the others mainly africans. ...19902195286
cloning and characterization of an abundant plasmodium knowlesi antigen which cross reacts with gambian sera.a 110 kda plasmodium knowlesi antigen, termed pk110, has been identified on the basis of messenger rna abundance in late schizonts. most plasmodium genes previously cloned have been identified by immune sera, which have selected immunodominant antigens composed of repeating epitopes. although pk110 was not selected by immune sera, it also contains amino acid repeats, indicating that this structure may be a common feature of malarial proteins. determination of 296 codons in the pk110 gene reveale ...19872444886
detection of plasmodium ovale in koraput district, orissa state.we report for the first time the detection of p. ovale infection in three patients in two hilly villages of koraput district, orissa state, india. the identification of the parasite was confirmed by the imperial colleage of science and technology, london.19892737703
[anemic plasmodium ovale malaria after 45 months' incubation]. 19872950492
[transfusion malaria caused by plasmodium ovale. a case]. 19882968562
concentration of plasmodium ovale- and plasmodium vivax-infected erythrocytes from nonhuman primate blood using percoll gradients.plasmodium vivax and plasmodium ovale schizont-infected erythrocytes were separated from peripheral blood by centrifugation using discontinuous percoll (colloidal silica) gradients. infected aotus monkey or chimpanzee blood was diluted and placed on a discontinuous gradient containing 30%, 40%, 45%, and 50% percoll (v/v in media) layers before centrifugation at 1,450 x g. parasitized erythrocytes were concentrated to greater than 95% schizont-infected cells in two bands that contained an average ...19863006527
seven patients with relapses of plasmodium vivax or p. ovale despite primaquine treatment.seven relapses of plasmodium vivax or plasmodium ovale despite standard treatment with primaquine (3.0 mg kg-1) daily for fourteen days are presented. the majority of patients came from areas outside the countries where resistance to primaquine is well known. the various possibilities of reasons for relapses are discussed.19873299660
relapsing malaria infection acquired in kenya.an american physician-traveler to east africa presented with manifestations of cerebral malaria and was treated with intravenous quinidine for chloroquine-resistant falciparum malaria. he later relapsed with plasmodium ovale infection, despite previous primaquine therapy. treatment of chloroquine-resistant malaria is discussed. the difficulty in diagnosing p. ovale infections and the predominance of this malaria species over p. vivax in east africa are reviewed.19873300055
circumsporozoite protein of the human malaria parasite plasmodium ovale identified with monoclonal antibodies.monoclonal antibodies (mabs) have been produced against plasmodium ovale sporozoites and used to characterize the circumsporozoite (cs) protein. six mabs were produced, and all were species specific. by using western blot (immunoblot) analysis, three polypeptides were detected: a predominant 51,000-mr polypeptide and two presumed precursor 57,000- and 67,000-mr molecules. the presence of a repeating epitope in the cs protein of p. ovale was demonstrated by using one of the mabs in a single-antib ...19883338845
stage-specific and species-specific antigens of plasmodium vivax and plasmodium ovale defined by monoclonal antibodies.monoclonal antibodies (mabs) were produced against the asexual blood stages of plasmodium vivax and plasmodium ovale and used to define antigens of plasmodial parasites in an indirect fluorescent antibody assay. the anti-p. vivax mabs produced two distinct patterns in the indirect fluorescent antibody assay. four patterns were found with the anti-p. ovale mabs. species-specific epitopes were defined for p. vivax and p. ovale; epitopes shared among all four species of human malaria parasites were ...19863536743
plasmodium ovale: in vitro development of hepatic stages.primary cultures of human hepatocytes, a culture-derived clone from the human hepatoma hep g2 line, and cultured rat hepatocytes were inoculated in vitro with plasmodium ovale sporozoites extracted from anopheles stephensi, an. gambiae, and an. dirus mosquitoes. penetration and differentiation of p. ovale sporozoites into trophozoite stage parasites occurred in all three cell types, but with a lower transformation rate in the hep g2 cell line than in the primary cultured hepatocytes. further mat ...19873678445
localization of circumsporozoite protein of plasmodium ovale in midgut oocysts.circumsporozoite (cs) proteins are the major proteins found on the surface of salivary gland sporozoites and are the protective antigens of several species of malaria parasites. little is known about the distribution of cs proteins in developing oocysts, however. immunoelectron microscopy with protein a-gold and a monoclonal antibody specific for the cs protein of plasmodium ovale was performed to investigate the distribution of cs protein within developing p. ovale oocysts. there was an almost ...19873679537
plasmodium ovale infections in natal. 19873686286
infection of chimpanzees with nigerian i/cdc strain of plasmodium ovale.seven splenectomized chimpanzees were infected with the nigerian i/cdc strain of plasmodium ovale. two of the animals had no history of previous malarial infection whereas three had been infected with p. vivax, one with p. malariae, and one with p. vivax and p. malariae. the two animals with no previous malarial experience had maximum parasitemias of 88,700 and 127,000 per mm3 while the other animals had maximum parasitemias ranging from 10,100 to 60,600 per mm3. anopheles freeborni, an. dirus, ...19873688304
ultrastructure of erythrocytic stages of plasmodium ovale in humans.an electron microscopic study of plasmodium ovale in humans supplied information on the fine structure of erythrocytic trophozoites, presegmenting schizonts and gametocytes. ultrastructural features of p. ovale appeared quite similar to those described in other mammalian malarial parasites. however, some minor structural variations were observed. the parasite was a fairly compact cell of an oval shape. however, occasionally trophozoites had slender cytoplasmic protrusions. ingestion of host cell ...19863728791
ultrastructure of human erythrocytes infected with plasmodium ovale.ultrastructural changes of the human erythrocytes infected with plasmodium ovale were studied, and differences of p. ovale from other human malarial parasites were discussed. four characteristic morphological alterations were observed on the host cells: caveola-vesicle complex, excrescence, nodule, and cytoplasmic cleft. caveola-vesicle complexes consisted of caveolae surrounded by vesicles in an alveolar fashion and were formed along the host cell plasmalemma. similar complexes have been report ...19863728792
haemostatic alterations in malaria correlate to parasitaemia.fibrin(ogen) degradation products, platelet counts, antithrombin iii, and the components of the factor viii complex were studied in a total of 80 patients with plasmodium falciparum, plasmodium vivax or plasmodium ovale infections. the haemostatic findings were correlated to the numbers of parasitized erythrocytes and to each other. the results indicate that haemostatic changes in malaria correlate with the degree of parasitaemia. evidence for moderate hyperfibrinolysis was found in patients wit ...19853933596
[plasmodium ovale malaria]. 19734204333
plasmodium ovale malaria acquired in viet-nam.four cases of plasmodium ovale malaria are reported among us servicemen stationed in viet-nam between january 1966 and march 1969. taken together with other cases cited by the authors, these provide strong evidence of the existence (sometimes disputed) of this plasmodium in continental south-east asia.none of the men had served in any other area of endemic malaria and their travel and medical histories suggest that all 4 infections were acquired by mosquito transmission. they constitute only 0.0 ...19704392940
[tertian malaria caused by plasmodium ovale. report of 2 cases]. 19744411108
[detection of plasmodium ovale in moscow in a patient infected in melanesia]. 19734805414
[plasmodium ovale (stephens 1922)]. 19694905936
malaria due to plasmodium ovale and vivax. 19714944666
fluorescent antibodies in human malaria, especially in plasmodium ovale. 19664961601
malaria due to plasmodium ovale in rhodesia. 19715111356
relapse activity in sporozoite-induced infections with a west african strain of plasmodium ovale. 19715131690
distribution of plasmodium ovale in the eastern, western and northern regions of uganda. 19675301742
plasmodium ovale infections in the philippines. 19685303913
plasmodium ovale in zambia. 19685306106
an analysis of the geographical distribution of plasmodium ovale.for a long time plasmodium ovale was considered a very rare causal agent of malaria, but recently it has been shown to be a fairly common parasite in africa. the authors analyse all the findings of p. ovale outside tropical africa and describe its distribution. this species is distributed in 2 areas, the first confined to tropical africa and the second to islands in the western pacific. the authors make a medico-geographical analysis of the distribution of p. ovale, and attempt to explain partic ...19695306622
[plasmodium ovale]. 19695369086
[does plasmodium ovale exist in madagascar?]. 19705537812
plasmodium ovale endemic in ethiopia. 19695794462
two cases of plasmodium ovale malaria from central thailand. 19695824291
a recently isolated west african strain of plasmodium ovale. 19665901625
the transmission of a west african strain of plasmodium ovale by anopheles freeborni and anopheles maculatus. 19665917627
[on a case of malaria due to plasmodium ovale contracted in guinea]. 19665976369
a case of plasmodium ovale infection. 19665981462
a case of plasmodium ovale malaria acquired in burma. 19836227111
monoclonal antibody identifies circumsporozoite protein of plasmodium malariae and detects a common epitope on plasmodium brasilianum sporozoites.we produced a hybridoma secreting an immunoglobulin g1 monoclonal antibody against the circumsporozoite protein of the human malaria parasite plasmodium malariae (uganda 1/cdc). the monoclonal antibody produces a circumsporozoite precipitation reaction when incubated with viable sporozoites of p. malariae and reacts at high titers with heat-fixed sporozoites in an indirect immunofluorescent antibody test. using the purified monoclonal antibody and western blot analysis, we identified two polypep ...19846381308
[late relapses in malaria caused by plasmodium ovale (stephens, 1922)]. 19846390576
a case of imported plasmodium ovale infection in trinidad, west indies. 19836868574
plasmodium: genus-conserved primers for species identification and quantitation.stable rnas have regions of primary sequence that are nearly identical in every member of the plasmodium genus and not found in the host or in other common pathogens. several "genus-conserved" sequences, which flank hypervariable regions, were identified within the small subunit ribosomal rna of plasmodium species. primers based on these conserved sequences permit amplification of species- or possibly even strain-specific sequences from samples of unknown composition. as an example of this appro ...19957556560
[a case of plasmodium ovale malaria with thrombocytopenia and an abnormality grade in fdp concentration despite the use of chloroquine as a malaria prophylaxis].a 45-year-old japanese male, who had been to the central african republic, was admitted to our hospital because of high fever with chills on july 29, 1994. he used chloroquine as a malaria prophylaxis during his stay and for 6 weeks after his return to japan. on admission, plasmodium ovale was detected in his blood smears and in the dna analysis. he was treated successfully with chloroquine (1500 mg over 3 day period) and primaquine (15 mg/day for 14 days beginning day 4). disappearance of malar ...19957751755
inoculum size and severity of malaria induced with plasmodium ovale.although it might be expected that the size of the infecting inoculum would influence the severity of the consequent malaria, evidence that it does so is scarce. using records from 80 non-immune neurosyphilis patients who received malaria therapy with a single strain of plasmodium ovale by blood inoculation, the relationships between the number of trophozoites inoculated, the prepatent period, and measures of severity of the resulting malaria were examined. the number of trophozoites was not rel ...19957785527
accuracy of routine laboratory diagnosis of malaria in the united kingdom.to study the accuracy of routine laboratory diagnosis of malaria with the aim of improving accuracy in diagnosis in the future.19947962629
pharmacokinetics and kinetic-dynamic modeling of an 8-aminoquinoline candidate anticyanide and antimalarial drug (wr242511).malaria is a major cause of health problems in a large portion of the world. the 8-aminoquinoline compound, primaquine, is one of the only compounds useful for relapses of plasmodium vivax and plasmodium ovale malaria. primaquine has several toxicities that include methemoglobinemia and hemolytic anemia. the induction of methemoglobinemia is a treatment for cyanide poisoning. we studied the pharmacokinetics and pharmacodynamics (percentage methemoglobin) for wr242511, an 8-aminoquinoline primaqu ...19948070311
in vitro cultivation of exoerythrocytic stages of the simian malaria parasites plasmodium fieldi and plasmodium simiovale in rhesus monkey hepatocytes.exoerythrocytic stage parasites of plasmodium fieldi and plasmodium simiovale, 2 simian malaria parasites related to the human malaria parasite plasmodium ovale, were cultured in vitro by inoculating primary cultures of hepatocytes from rhesus monkeys (macaca mulatta) with sporozoites. less than 1% of sporozoites developed into schizonts for either species. structure and size of the liver stages in both species were similar to previous in vivo descriptions, and the time required for in vitro mat ...19948195940
plasmodium ovale: observations on the parasite development in saimiri monkey hepatocytes in vivo and in vitro in contrast with its inability to induce parasitemia.exoerythrocytic stage parasites of the human malaria parasite plasmodium ovale were cultured in vitro by inoculating primary cultures of hepatocytes from saimiri sciureus boliviensis monkeys with sporozoites. morphology and size of the liver stages were similar to previous in vivo descriptions in humans and chimpanzees. saimiri monkeys did not develop parasitemia after repeated inoculations with p. ovale sporozoites. however, liver-stage parasites were observed in liver biopsies performed 7 days ...19948206138
post-transfusion acquired malaria complicating orthotopic liver transplantation.early infectious complications within the first 3 months of orthotopic liver transplantation are common and are associated with significant morbidity and mortality. here we report the first case of transfusion-acquired malaria in an orthotopic liver transplantation recipient. the patient was found to have plasmodium ovale malaria during evaluation of a severe febrile illness. the infection was traced to a platelet transfusion and responded to treatment with chloroquine. risk factors associated w ...19968607511
[malaria and drug resistance].drug resistance is a major problem in malaria. the resistance mechanism remains unresolved but contributing factors are probably heavy drug use, parasite selection, cross resistance and genetic influences of drugs. plasmodium ovale en p. malariae are sensitive to the current antimalarial drugs. p. vivax has some chloroquine resistant strains, notably on papua new guinea, irian jaya and other islands in the pacific. the geographical distribution of p. falciparum strains resistant to proguanil and ...19968618636
the nigerian i/cdc strain of plasmodium ovale in chimpanzees.the chimpanzee is the only animal host currently available that can support the development of the human malaria parasite plasmodium ovale. thirty-one infections with the nigerian i/cdc strain were induced in splenectomized chimpanzees. maximum parasite counts ranged from 1,240 to 127,224/microliters. infections were transient and unpredictable. anopheles stephensi, anopheles gambiae, anopheles freeborni, and anopheles dirus mosquitoes were infected by feeding through parafilm membranes on hepar ...19968636850
dna diagnosis of malaria using microtiter plate-hybridization.we have developed a new diagnostic method "microtiter plate-hybridization" (mph) for the detection of human malaria parasite in which the target dna sequence of the 18s ribosomal rna gene is amplified by polymerase chain reaction and hybridized with the species-specific probes immobilized on a microtiter well. the pcr products bound on a well are visualized by the biotin-streptavidin system and the following chromogenic reaction. this method has allowed us to detect and identify the four species ...19958841641
sequence variation in the 18s rrna gene, a target for pcr-based malaria diagnosis, in plasmodium ovale from southern vietnam.field surveys of malaria were performed in southern vietnam by using an acridine orange staining method for rapid diagnosis and a pcr-based, microtiter plate hybridization method for accurate diagnosis. a total of three patients of plasmodium ovale infection were detected, but pcr-amplified dna of the p. ovale isolates from two of the patients did not hybridize with the p. ovale-specific probe. analysis of the target sequence in the 18s rrna gene indicated that in the dna of isolates from both p ...19968862600
short report: rosette formation in plasmodium ovale infection.red blood cells infected by mature stages of plasmodium ovale obtained from a 56-year-old thai patient formed rosettes readily with uninfected erythrocytes. ex vivo, the ring stage-infected erythrocytes matured well under the in vitro conditions used for p. falciparum culture, and the infected erythrocytes formed rosettes when the parasites became mature trophozoites. these rosettes were stable and remained intact until completion of schizogony. plasmodium ovale rosettes were similar to those fo ...19968940990
atovaquone plus proguanil is an effective treatment for plasmodium ovale and p. malariae malaria. 19969015517
pyronaridine for treatment of plasmodium ovale and plasmodium malariae infections.the clinical efficacy of oral pyronaridine was assessed in 22 symptomatic cameroonian patients infected with plasmodium ovale or plasmodium malariae. all patients were cured on or before day 4. in vitro drug assays confirmed the sensitivity of p. ovale and p. malariae isolates to chloroquine and pyronaridine.19979333075
detection of plasmodium ovale malaria parasites by species-specific 18s rrna gene amplification.a polymerase chain reaction (pcr) assay was developed for the specific detection of plasmodium ovale, one of the four malaria parasites that infect humans. on the basis of sequence variation of the plasmodium 18s ribosomal rna (rrna) gene, oligonucleotide primers for pcr were designed to amplify various fragments of the p. ovale gene. using a recombinant plasmid with the complete p. ovale 18s rrna gene as target, 59 primer combinations were tested so that at least one of the pairs was species-sp ...19979500806
a variant of plasmodium ovale; analysis of its 18s ribosomal rna gene sequence.we report here a new variant of human malaria parasite found by comparison of diagnostic results obtained from a new dna diagnostic method named microtiter plate-hybridization (mph) and traditional microscopic method. total five cases of malaria were diagnosed as microscopy-positive but mph-negative; one case was found in epidemiological research in vietnam and four cases were obtained from imported malaria in japan. although they were quite similar to typical p. ovale morphologically in microsc ...19979586115
high prevalence of plasmodium malariae and plasmodium ovale in malaria patients along the thai-myanmar border, as revealed by acridine orange staining and pcr-based diagnoses.the prevalence of the four human malaria parasites was investigated among malaria patients at northern, central and southern towns in thailand along the border with myanmar between september 1995 and may 1996. thin smears obtained from 548 thai and burmese patients were reviewed by an acridine orange staining method, and many mixed infections with two to four species, including p. malariae and p. ovale, were detected. these diagnostic results were compared with those by two pcr-based diagnoses, ...19989623932
plasmodium ovale in lao pdr. 19979656397
non-immune patients in the democratic republic of são tomé e principe reveal a high level of transmission of p. ovale and p. vivax despite low frequency in immune patients.malaria parasite species circulating in immune inhabitants of the democratic republic of são tomé e principe (drstp) and those acquired by non-immune travellers returning from this country have been compared. using sensitive detection and species identification by pcr, plasmodium parasites were found in the blood of 16 of the 43 travellers, who reported during the first 8 months of 1995 to a clinical diagnosis laboratory in lisbon. plasmodium vivax was found in four (25%) and plasmodium ovale in ...19989698266
current status and prospects of malaria vaccines.malaria is a parasitic disease caused by four plasmodium species infecting humans, plasmodium falciparum, plasmodium vivax, plasmodium ovale, and plasmodium malariae. the parasite is transmitted by the anopheles mosquitoes that flourish in warm climates. these vectors thus are present in many tourist areas of the world, including africa, asia, and south america. known in china, as far back as 2700 bc, malaria was controlled by medicinal plants or drugs. this was until drug resistance occurred, b ...19959815369
plasmodium ovale in a highly malaria endemic area of senegal.during 4 months, from june to september 1990, the population of dielmo village, senegal, an area of intense and perennial malaria transmission, was enrolled in a follow-up study including daily clinical surveillance and bi-weekly malaria parasitaemia monitoring. thick blood film examinations indicated that 48.5% of children (49/101) and 32.4% of adults (34/105) were infected at least once by plasmodium ovale during the study period; 148 distinct episodes of patent parasitaemia were observed, wit ...19989861368
plasmodium ovale in south africa. 19989861386
retrospective study of malaria cases treated in newcastle general hospital between 1990 and 1996.malaria, in particular falciparum malaria, continues to pose a substantial risk to travelers to endemic areas.19989876194
multispecies plasmodium infections of humans.we analyzed point-prevalence data from 19 recent studies of human populations in which either plasmodium ovale or plasmodium vivax co-occur with plasmodium falciparum and plasmodium malariae. although the only statistical interactions among, sympatric congeners are pairwise, the frequencies of mixed-species infections relative to standard hypotheses of species sampling independence show no strong relation to overall malaria prevalence. the striking difference between the p. falciparum-p. malaria ...199910207356
malaria prevention in travelers.the prevention of malaria in travelers is becoming a more challenging clinical and public health problem because of the global development of drug-resistant plasmodium strains of malaria and the increasing popularity of travel to exotic locales. travelers can reduce their risk of acquiring malaria by using bed netting, wearing proper clothing and applying an insect repellent that contains n,n-diethyl-meta-toluamide. chloroquine, once the standard agent for weekly malaria prophylaxis, is no longe ...199910323359
rare quadruple malaria infection in irian jaya indonesia.we report an exceptional finding from a blood slide collected in a remote area in the western half of new guinea island (irian jaya province, indonesia). one adolescent patient was found patently coinfected with all 4 known human malaria species, plasmodium falciparum, plasmodium vivax, plasmodium malariae, and plasmodium ovale. diagnostic erythrocytic stages of all 4 species were clearly seen in the peripheral blood. a nested polymerase chain reaction, using species-specific primer pairs to det ...199910386460
imported tertian malaria resistant to primaquine.in plasmodium vivax and plasmodium ovale malaria, some of the liver stage parasites remain dormant. the activation of these dormant forms (called hypnozoite) can give rise to relapse weeks, months or years after the initial infection. to prevent relapses, a course of primaquine may be given as terminal prophylaxis to patients. different strains of plasmodium vivax vary in their sensitivity to primaquine and, recently, cases of relapse of plasmodium vivax after this standard primaquine therapy we ...199910461431
[rapid resolution of plasmodium ovale malarial attacks using artesunate (arsumax)].this randomized, non-comparative clinical trial without placebo was carried out to assess the efficacy and tolerance of artesunate for treatment of acute plasmodium ovale malarial attacks. thirty cameroonese patients were included. all presented acute plasmodium ovale malarial attacks with parasitemia in excess of 500 asexual forms per mm3. four days after treatment with artesunate, all 30 patients were asymptomatic with no parasitemia. reduction rates were 93.9 p. 100 for asexual forms and 75.4 ...199910472581
how prevalent are plasmodium ovale and p. malariae in east asia?plasmodium ovale and plasmodium malariae, two of the four human malaria parasites, are usually found at very low prevalence in east asia, even in areas with intense malaria transmission. in this article, fumihiko kawamoto, qing liu, marcelo ferreira and indah tantular review data obtained in recent field surveys, using alternative diagnostic methods such as acridine orange staining and pcr-based methods, to evaluate the prevalence of these two malaria species in east asia. they argue that these ...199910481157
usefulness of seminested multiplex pcr in surveillance of imported malaria in spain.the use of a new pcr-based method for the diagnosis of malaria in the spanish malaria reference laboratory has promoted an increase in confirmed cases of malaria. from august 1997 to july 1998, a total of 192 whole-blood samples and 71 serum samples from 168 patients were received from the hospitals of the spanish national health system. most of the patients came from west-central african countries (85%). this molecular method showed more sensitivity and specificity than microscopy, detecting 12 ...199910488189
plasmodium ovale in southern africa. 199910492808
cloning and characterization of iron-containing superoxide dismutase from the human malaria species plasmodium ovale, p. malariae and p. vivax.the iron-containing superoxide dismutase (fesod) gene from three human malaria species, namely plasmodium ovale, p. malariae and p. vivax, was amplified by polymerase chain reaction, cloned and then sequenced. comparisons of their deduced amino acid sequences with that of the fesod from p. falciparum revealed a very low polymorphism at the fesod locus in human malaria species. one p. ovale and the p. vivax fesod genes presented the same nucleotide sequence as that of the p. falciparum strain hb3 ...199910599926
erythrocyte fy antigen phenotyping helps differentiate so-called benign tertian malarias.isolated cases of malaria are increasing in frequency in nonendemic countries. blood film examination remains a mainstay of diagnosis of these sporadic cases because immunologic and molecular methods are unavailable, expensive, and problematic. two tertian malarial species, plasmodium vivax and plasmodium ovale, may appear to be similar morphologically. plasmodium ovale infection is infrequent, and misdiagnosis of this species is common. plasmodium vivax infection can be ruled out, however, if a ...200010656744
[increase of malaria among migrants in amsterdam-zuidoost].in a general practice in amsterdam southeast in 1998 a delayed first attack of plasmodium ovale infection was diagnosed in a 13-year-old girl from ghana, malaria tropica with a low parasitaemia index in a 43-year-old ghanaian man and a 8-year-old ghanaian girl, and plasmodium vivax infection in a 44-year-old surinam woman. the ghanaian patients had visited their native country, the surinam woman had contracted the infection during a visit to india. all patients responded well to antimalaria medi ...200010674108
[diagnostic test to identify human plasmodium species by the quantitative buffy coat test].the quantitative buffy coat system (qbc test) was designed for rapid diagnosis of malaria by identifying the presence of hemoparasites. the main drawback of the technique is failure to identify the plasmodium species. the purpose of this study was to attempt to remedy this problem by studying the distribution of the parasites at the bottom of the test tube. indeed since the qbc test is based on gradient centrifugation of blood components, the distribution of the parasites in the test tube depend ...199910701207
a study of the urban malaria transmission problem in khartoum.a study of malaria prevalence and transmission was carried out in khartoum, the capital of sudan. the sentinel sites were el manshia, an urban area on the blue nile and ed dekheinat, a lower-income peri-urban area bordering the white nile. anopheles arabiensis, the only malaria vector encountered, was present throughout the year although vector density varied seasonally. plasmodium falciparum was the only species found in el manshia. in ed dekheinat p. falciparum, plasmodium ovale and plasmodium ...200010708656
plasmodium ovale malaria in delhi.a case of ovale malaria in a child from delhi is reported. urban malaria ecotypes caused by p. ovale has never been seen before. characteristic morphological features of the parasite in stained blood film confirmed its identification.199910798048
"plasmodium ovale infection in delhi" published in indian journal of pediatrics jan-feb 1999; vol. 66 (1): 143-145. 199910798097
plasmodium ovale infections detected by pcr assay in lao pdr.plasmodium ovate infection was demonstrated in 5 out of 143 inhabitants in a village in lao pdr by blood microscopy and pcr assay. although the specimen confirmed to be positive for p. ovale by microscopical examination was only one, the target sequences in the 18s rrna genes of malaria parasite detected in all of the five cases were consisted with those of p. ovale by the pcr assay. this is the first report concerning the presence of so many cases with p. ovale infection in lao pdr.199910928349
plasmodium ovale species in papua new guinea--lest we forget.the microscopical diagnosis of plasmodium ovale infection is reviewed and its similarity to plasmodium vivax emphasized. its presence in papua new guinea has been recognized for many years, from a time not long after stephens first described the species in 1922, but it is rarely reported. there is no doubt of its presence in papua new guinea, together with p. falciparum, p. vivax and p. malariae, but its exact prevalence and distribution has not been determined.199810934553
difficulties in the prevention, diagnosis, and treatment of imported malaria.imported malaria is quite common in the united states. increasing antimalarial drug resistance and changes in travel patterns may have important implications for the prevention, clinical presentation, and management of this disease.200010979063
malaria epidemiological situation in italy and evaluation of malaria incidence in italian travelers.malaria was endemic throughout the country until it was eradicated nearly 50 years ago. since then, mainly imported malaria cases have been reported to the national health service, with an increasing trend. the aim of this study was to present a detailed analysis of the current epidemiological situation of malaria in italy, and to make a first attempt to calculate the incidence of malaria in italian international travelers.200111182603
authors' reply to "plasmodium ovale infection". 200011262998
imported malaria treated in melbourne, australia: epidemiology and clinical features in 246 patients.imported malaria is increasing in nonendemic countries, including australia. the objective of this study was to describe the epidemiology and clinical features of travelers with imported malaria presenting to a specialist infectious diseases hospital.200111285166
presence of three distinct ookinete surface protein genes, pos25, pos28-1, and pos28-2, in plasmodium ovale. 200111295191
parasitic procrastination: late-presenting ovale malaria and schistosomiasis.a 29-year-old woman with ovale malaria (most likely contracted, together with asymptomatic schistosomiasis, in east africa two years previously) had fever, nausea and confusion, jaundice, anaemia, thrombocytopenia, hyponatraemia and hypokalaemia. she was initially diagnosed with and treated for blood-smear-positive vivax malaria. because of the unusual clinical presentation, blood was analysed by a malaria species-specific nested polymerase chain reaction (pcr) assay which identified plasmodium ...200111548081
[malaria in georgian republic].due to the prevailing natural conditions, georgia is an endemic country for malaria. all types were widespread in the country, with the exception of plasmodium ovale malaria. a campaign of large-scale and comprehensive measures undertaken by the authorities lead to complete elimination of malaria as an indigenous disease in 1970.200111548306
detection of plasmodium ovale by the ict malaria p.f/p.v. immunochromatographic test. 200111700187
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