| infection and transmission studies with plasmodium simiovale in the macaca mulatta monkey. | six different anophelines--anopheles freeborni, an. b. balabacensis, an. maculatus, an. stephensi, an. atroparvus, and an. quadrimaculatus--were shown to be susceptible to infection with plasmodium simiovale when fed upon splenectomized macaca mulatta monkeys between the 1st and 26th days of patent parasitemia. transmission was obtained via the bites of an. b. balabacensis and an. maculatus mosquitoes. prepatent periods in m. mulatta monkeys following sporozoite inoculation ranged from 11 to 20 ... | 1979 | 117087 |
| hypnozoites of plasmodium simiovale. | hypnozoites of plasmodium simiovale were detected in liver biopsies from a rhesus monkey (macaca mulatta) inoculated eight days previously with sporozoites from heavily infected anopheline mosquitoes. the tissue forms, 6 mu in diameter, were found within the cytoplasm of hepatic parenchymal cells by immunofluorescence and restained with giemsa. this is the first report of latent, pre-erythrocytic stages from an ovale-type relapsing malaria. | 1991 | 1877716 |
| observations on the relapse activity of plasmodium simiovale in the rhesus monkey. | | 1974 | 4206879 |
| studies on the exoerythrocytic stages of simian malaria. vii. plasmodium simiovale. | | 1972 | 4622280 |
| monoclonal antibodies to the circumsporozoite protein repeats of a plasmodium vivax-like human malaria parasite and plasmodium simiovale. | we have recently described a plasmodium vivax-like human malaria parasite. the circumsporozoite protein of this parasite is identical to that of a simian malaria parasite, p. simiovale, but different from two known types of p. vivax. here, we describe the production of two monoclonal antibodies, pam 172 and pam 135, specific for the circumsporozoite protein repeat sequence apganqeggaa of the p. vivax-like malaria parasite. these two monoclonal antibodies recognized air-dried sporozoites of p. si ... | 1994 | 8168975 |
| in vitro cultivation of exoerythrocytic stages of the simian malaria parasites plasmodium fieldi and plasmodium simiovale in rhesus monkey hepatocytes. | exoerythrocytic stage parasites of plasmodium fieldi and plasmodium simiovale, 2 simian malaria parasites related to the human malaria parasite plasmodium ovale, were cultured in vitro by inoculating primary cultures of hepatocytes from rhesus monkeys (macaca mulatta) with sporozoites. less than 1% of sporozoites developed into schizonts for either species. structure and size of the liver stages in both species were similar to previous in vivo descriptions, and the time required for in vitro mat ... | 1994 | 8195940 |
| global occurrence of plasmodium vivax-like human malaria parasite. | a plasmodium vivax-like human malaria parasite was recently identified from madang, a holoendemic malarious region in papua new guinea. the complete nucleotide sequence of the circumsporozoite (cs) protein gene of this parasite is presented here. the cs protein of this parasite has an 11-mer repeat sequence and is different from the other known cs protein genes of human malaria parasites. however, it is identical to the cs protein gene of a monkey malaria parasite, plasmodium simiovale. this p. ... | 1993 | 8245533 |
| correlation between positive serology for plasmodium vivax-like/plasmodium simiovale malaria parasites in the human and anopheline populations in the state of acre, brazil. | antibodies against the plasmodium vivax-like/p. simiovale malaria parasite circumsporozoite repeat peptide (apganqeggaa)3 were determined by enzyme-linked immunosorbent assay (elisa) in 120 sera randomly collected in 1994 from adults in 3 localities of the malaria endemic area in the state of acre, brazil; antibody was detected in 18 (15%). a 'sandwich' elisa using monoclonal antibody (mab) pam 172, directed against the same peptide, was carried out on 1207 anopheles oswaldoi, 12 of which (1.0%) ... | 1998 | 9764317 |
| malaria epidemiology in low-endemicity areas of the atlantic forest in the vale do ribeira, são paulo, brazil. | we describe a seroepidemiological survey of malaria prevalence in two areas of low endemicity: intervales state park and alto ribeira state tourist park (petar). both are located in the vale do ribeira in the state of são paulo, brazil. in this study, 318 subjects from both areas had their blood analyzed for the presence of malaria parasites by thin and thick blood smears. one hundred and sixty-three (51.2%) of the subjects were from intervales state park and 155 (48.7%) were from petar. we anal ... | 2006 | 17126279 |
| the evolution and diversity of a low complexity vaccine candidate, merozoite surface protein 9 (msp-9), in plasmodium vivax and closely related species. | the merozoite surface protein-9 (msp-9) has been considered a target for an anti-malarial vaccine since it is one of many proteins involved in the erythrocyte invasion, a critical step in the parasite life cycle. orthologs encoding this antigen have been found in all known species of plasmodium parasitic to primates. in order to characterize and investigate the extent and maintenance of msp-9 genetic diversity, we analyzed dna sequences of the following malaria parasite species: plasmodium falci ... | 2013 | 24044894 |
| non-human primate malaria parasites: out of the forest and into the laboratory. | the study of malaria in the laboratory relies on either the in vitro culture of human parasites, or the use of non-human malaria parasites in laboratory animals. in this review, we address the use of non-human primate malaria parasite species (nhpmps) in laboratory research. we describe the features of the most commonly used nhpmps, review their contribution to our understanding of malaria to date, and discuss their potential contribution to future studies. | 2016 | 27748213 |
| identification of a vir-orthologous immune evasion gene family from primate malaria parasites. | the immune evasion gene family of malaria parasites encodes variant surface proteins that are expressed at the surface of infected erythrocytes and help the parasite in evading the host immune response by means of antigenic variation. the identification of plasmodium vivax vir orthologous immune evasion gene family from primate malaria parasites would provide new insight into the evolution of virulence and pathogenesis. three vir subfamilies viz. vir-b, vir-d and vir-g were successfully pcr ampl ... | 2014 | 24477117 |