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[epidermophyton floccosum (harz) langeron et milochevitch in eastern bohemia (author's transl)]. 1975124225
[epidemiology and clinical aspects of a mycosis caused by epidermophyton floccosum]. 1976139790
fungal diseases in shiraz.in 122 patients with fungal diseases studied over a six month period, sixty were seen with dermatophyte infections. tinea pedis, cruris and ungruium occurred mainly in adult males attending the private hospital and tinea corporis and capitis children attending the university hospital. the organisms found were trichophyton rubrum, t. mentagrophytes, t. schonleinii, t. tonsurans, epidermophyton floccosum and microsporum canis. infections with candida albicans occurred both in the urban and rural p ...1978148630
[randomised investigations of some tyrolean swimming pools for the presence of trichomonas vaginalis and pathogenic fungi (author's transl)].trichomonads were not demonstrated either microscopically or by culture in water samples from 15 public open air swimming pools in the tyrol. on the other hand, a small number of pathogenic fungi (candida albicans, trichophyton mentagrophytes, tr. verrucosum) were cultured from pool water with a free chlorine content of less than 0.35 mg/l (dpd 1). dermatophytes could also be demonstrated by cultures of the coatings on the surfaces of tiles in the showers, and of pool surrounding-and cabin tract ...1975239503
epidemiologic study of dermatophytoses in salamanca (spain).an epidemiologic study of the dermatophytoses in salamanca (spain) from 1973 to 1976 was performed. dermatophyte species were identified in 224 patients with clinical tinea infections; 31 bovines, 18 rodents and 70 soil samples. the prevalence of trichophyton verrucosum and epidermophyton floccosum was strikingly high in relation to other statistics. the most common clinical forms were tinea corporis and tinea cruris. tinea capitis by anthropophilic species was uncommon.1979542885
storage of epidermophyton floccosum at-22 c. 1978723916
isolation of ethyl p-methoxycinnamate, the major antifungal principle of curcumba zedoaria.an antifungal principle of the dried rhizomes of curcuma zedoaria was extracted with hot ethanol. by successive chromatography on neutral alumina and silica gel, three antibiotic compounds a, b, and c, all active against trichophyton rubrum, aspergillus niger and saccharomyces cerevisiae, were obtained in chemically pure form. by uv, ir, pmr and ms analysis, the structure of the most abundant one of these compounds (c, 69.8%; h, 6,8%; and 0.23.4%) was assigned as ethyl p-methoxycinnamate (epmc). ...1976785141
lymphocyte transformation in vitro in dermatophytosis.peripheral blood lymphocytes from 59 patients with dermatophytosis and from nine young healthy women were studied by the lymphocyte transformation test (lt) using mitogens and bacterial as well as fungal antigens. the latter included candida albicans (ca) and four dermatophyte species, viz. trichophyton rubrum (tr), trichophyton mentagrophytes (tm), epidermophyton floccosum (ef) and microsporum canis (mf). most of the patients showed normal transformation in response to mitogens and non-dermatop ...1976793301
studies on the biological effects of deuteriated organic compounds. i. antifungal activity of perdeuteriated fatty acids on dermatophytes in vitro.the antifugal activity of some perdeuteriated fatty acids, with normal chain 11 to 18 carbon atoms, was investigated on common dermatophytes epidermophyton floccosum, microsporum canis, trichophyton mentagrophytes and t. rubrum under in vitro conditions. these studies were performed by dilution technique and with respiratory measurements, perdeuteriation of some fatty acids increases their inhibitory effect on the dermatophyte growth. perdeuteriated n-hendecanoic acid proved to be the most activ ...1976967223
carbohydrate composition of the isolated cell walls of dermatophytes.in an attempt to evaluate taxonomic character of sugar composition of dermatophytes, the purified cell walls from 13 species are analyzed on neutral sugar composition by gas liquid chromatography. the results were principally compatible with those obtained by conventional morphological examination. neutral sugar components of dermatophytes cell walls were mannose and glucose in the ratio of 1:2.7 for epidermophyton and 1:1.4 for microsporum. there were two types in trichophyton, in which the rat ...19751128648
isolation of a peptido-polysaccharide from the dermatophyte epidermophyton floccosum and a study of its reaction with human c-reactive protein and a mouse anti-phosphorylcholine myeloma serum.culture filtrate extracts from a number of dermatophyte and aspergillus species precipitate with human c-reactive protein (crp) and the lectin con a. using immobilized con a, a peptidopolysaccharide (pps) has been isolated from epidermophyton floccosum culture filtrate by affinity chromatography and shown to precipitate with con a, human crp sera and a mouse myeloma serum with specificity for phosphorylcholine (pc). the pps contains carbohydrate (60%), protein (35%), choline and phosphate. the c ...1977885587
aflatoxin-like compounds produced by dermatophytes.using the method of thin-layer chromatography there were investigated the chloroform extracts of 30 dermatophyte mycelia. it was found the presence of aflatoxin-like compounds in six mycelium extracts only, which chromatograms showed the equal rf and the colour of the strains to the strains to the standard aflatoxin extract of bruished peanuts grain rossetti. those six mycelia were: epidermophyton floccosum, nannizzia fulva, n. persicolor, arthroderma gloriae, trichophyton concentricum and t. ga ...19751170494
tinea cruris: diagnostic confusion due to isolation of candida albicans alone.the diagnostic importance of the isolation of candida albicans from a skin lesion is often uncertain. in a 68-year-old man from whose lesions only c. albicans was originally isolated trichophyton rubrum and epidermophyton floccosum were also isolated when the growth of the yeast was inhibited in a selective medium. the use of this selective medium, casamino acids erythritol albumin agar, ensures the proper interpretation of the significance of the presence of c. albicans in skin lesions.1976773524
clinical evaluation of clotrimazole. a broad-spectrum antifungal agent.the efficacy and safety of the broad-spectrum, topically applied antifungal agent clotrimazole were evaluated in two double-blind, multicentric trials. ten investigators reported on a total of 1,361 cases in which a 1% solution or a 1% cream formulation was compared with its respective vehicle. clotrimazole was therapeutically effective, as confirmed by mycological cure (negative microscopy and culture) and clinical improvement, in tinea pedis, tinea cruris, tinea corporis, pityriasis versicolor ...1976769697
comparison of the in vitro antifungal activities of miconazole and a new imidazole, r41,400.r41,400 is a recently synthesized, water-soluble imidazole. its antifungal properties were compared in vitro with those of miconazole using an agar dilution procedure and 175 isolates of human fungal pathogens. the filamentous forms of histoplasma capsulatum and blastomyces dermatitidis were inhibited by less than or equal to 2 microgram of either drug/ml; coccidioides immitis was inhibited by less than or equal to 0.5 microgram of r41,400/ml. among the yeasts tested, cryptococcus neoformans and ...1978681800
antibiotic production by dermatophyte fungi.thirty-two clinical isolates of anthropophlic dermatophytes were examined for their capacity to produce antibiotics in liquid culture and on human stratum corneum in vitro. antibiotics were detected and classified using agar diffusion bioassays and chromatographic analysis. twenty-four isolates produced antibiotic substances in liquid culture filtrates; some strains produced more than one antibiotic. only four isolates produced detectable levels of antibiotics when grown on stratum corneum unles ...1978632806
membrane ultrastructure of hyphae of epidermophyton floccosum: as observed by freeze-fracture electron microscopy. 1977604412
dermatophytosis survey in lagos state of nigeria.a dermaphytosis survey covering 3,860 schoolchildren was conducted in lagos, nigeria, between january 1973 and january 1974. seven species of dermatophytes, namely, trichophyton mentagrophytes (four isolates), t. rubrum (three isolates), t. soundanense (11 isolates), microsporum canis (five isolates), m. gypseum (two isolates), m audouinii (four isolates), and epidermophyton floccosum (three isolates) were recovered from specimens collected from the hair, skin and scalp scrapings of 81 schoolchi ...1977595081
an unusual lipid in the human pathogenic fungus epidermophyton floccosum.the dermatophyte epidermophyton floccosum contains an unusual lipid characterized as 1(3),2-diacylglyceryl-3(1)-o-4'-(n,n,n-trimethyl)homoserine. its concentration in e. floccosum is approx. 15% of the polar lipids. the role of this lipid in the biosynthesis of polar lipids and fatty acids is not yet known. however, it is interesting from a chemotaxonomic viewpoint that the lipids from two other genera of dermatophyte, microsporum cookei and trichophyton rubrum do not contain this novel lipid.1979486519
dermatophyte species, microscopic and cultural examination.the dermatophytes epidermophyton floccosum, microsporum canis, trichophyton mentagrophytes var. interdigitale, t. rubrum, and t. verrucosum were compared with respect to the direct microscopic examination of a clinical material and the number of colonies obtained by culture. it was found that the results of microscopy as well as of culture depended to a marked extent upon which species were the cause of the mycosis. the extremes were e. floccosum and t. mentagrophytes var. interdigitale which sh ...1979481562
isolation of dermatophytes from clinically normal sites in patients with tinea cruris.sixty patients clinically suspected of tinea cruris were studied by collecting skin scrapings from the site of their lesions and six clinically normal sites including the thighs, scrotum, crural clefts, natal cleft and the web between their 4th and 5th toes. dermatophytes were detected in scrapings in 46 (77%) and by culture in 36 (60%) patients from lesions. trichophyton rubrum was isolated from 32 and epidermophyton floccosum from 4 patients. dermatophytes were also isolated with maximum isola ...19921494358
antifungal activity of allylamines on epidermophyton floccosum: scanning electron microscopy study.the action of allylamine antifungal agents on epidermophyton floccosum was studied using scanning electron microscopy. after 7 days of culture on sabouraud dextrose agar, epidermophyton floccosum samples were brought in contact with concentrations of 0.2 and 2 micrograms ml-1 and 0.01 and 0.1 micrograms ml-1 of naftifine and terbinafine, respectively. lesions observed after 24 h, 3 and 7 days of contact were mainly on the structure and rigidity of the mycelial and macroconidial wall. they were c ...19921494360
phospholipids of epidermophyton floccosum. 1979429049
comparison of in vitro activity of undecylenic acid and tolnaftate against athlete's foot fungi.undecylenic acid and tolnaftate were tested in an in vitro test system to evaluate their relative "killing time" efficacy against trichophyton mentagrophytes, trichophyton rubrum, and epidermophyton floccosum. commercial products containing these active agents were tested similarly. the pure active agents were equivalent in activity. the commercial product containing undecylenic acid appeared to be more effective against the test organisms than did the product containing tolnaftate.1979423138
[in vitro effectiveness of salicylic, benzoic and boric acid and diiodine thymol solutions on various strains of dermatophytes].in order to study the in vitro behavior of the drug used according to our formula cultures of trichophyton mentagrophytes. trichophyton rubrum, trichophyton verrucosum, trichophyton tonsurans, microsporum canis, microsporum gallinae, microsporum audouinii, microsporum gypseum and epidermophyton floccosum were prepared in order to prove its efficacy. it was found no growth in cultures to which the drug was added in different concentrations thus proving its efficacy as a fungistatic element. the i ...1979395583
[ultrastructure of hyphal walls of epidermophyton floccosum as observed by freeze-fracture electron microscopy: with special reference to the outer most layer ("exo-layer") of the cell wall (author's transl)]. 1979311868
[localization of solitary dermatophytic lesions in man].the occurrence of three causative organisms of the so called intertriginous dermatophytoses--epidermophyton floccosum, trichophyton mentagrophytes var. interdigitale and t. rubrum--was compared according to the localization of the lesions. the differentiation of invasion into solitary and combined sites showed a prevalence of e. floccosum in solitary lesions and t. rubrum in combined lesions. in t. mentagrophytes var. interdigitale, the frequency of occurrence of both types of the lesions was ap ...1975126977
the clinical significance of cutaneous reactions to trichophytin in dermatophytosis.an intracutaneous test was performed in 114 patients with dermatophytosis verified by culture and in 32 control subjects, unsing purified trichophytin (according to the ethylene glycol method) and commercially available trichophytin. immediate reactions occurred with both trichophytin antigens at a similar frequency in 12-14% of cases. delayed reactions occurred significantly more often to the purified trichophytin in patients with dermatophytosis (36%) but in none of the controls. immediate rea ...197876393
studies of the antigenic structure of trichophyton rubrum, trichophyton mentagrophytes, microsporon canis, and epidermophyton floccosum by crossed immuno-electrophoresis.by means of crossed immuno-electrophoresis, 35 antigens of t. rubrum, 26 of t. mentagrophytes, 35 of m. canis, and 25 of e. floccosum have been demonstrated. tandem crossed immuno-electrophoresis has revealed two antigens common to t. rubrum and the other species, which, however, differ within the species. no common antigens have been demonstrated between t. mentagrophytes, m. canis, and e. floccosum. the technique for preparation of extracts and production of immune serum is described, and the ...197660875
the effect of sodium chloride on the growth and morphology of dermatophytes and some other keratolytic fungi.a study of the influence of various concentrations of nac1 on 21 species of dermatophytes and other keratolytic fungi was made. based on the sensitivity of the species to various concentrations of nac1, it was possible to divide them into five groups. microsporum ferrugineum and trichophyton concentricum and t. tonsurans were the most sensitive to nac1 and were inhibited by 5%. the greatest number of species were inhibited by 12% nac1. the fungi most tolerant to nac1 were m. cookei and m. nanum, ...19751148934
isolation, ultrastructure and chemical composition of the outermost layer ("exo-layer") of the epidermophyton floccosum cell wall.the outer-most layer ("exo-layer") of the wall was isolated from cell walls of epidermophyton floccosum. the pure cell walls, obtained by disruption in a ribi cell fractionator, sonication and centrifugation, were digested with snail enzyme for 12 h. thereafter, the exo-layer preparation was obtained as the fraction resistant to the snail enzyme. electron microscopy showed that the exo-layer is a thin, stranded network structure 10-20 nm thick. chemical analysis of the exo-layer showed that the ...19751148232
isolation of dermatophytes, candida species and systemic fungi from dermatologic specimens in montréal, 1963 to 1973.of 10 057 specimens of scrapings from skin, nails and scalp examined for dermatophytes, yeasts, pityriasis versicolor and systemic mycoses between 1963 and 1973, 30.4 percent were positive for fungi. skin produced the highest proportion (68.6 percent) of positive scrapings, scalp the lowest (4.2 percent). trichophyton rubrum was the predominant species (23.6 percent); of lesser prevalence were microsporum canis (9.3 percent), t. mentagrophytes (8.4 percent) and epidermophyton floccosum (4.8 perc ...19751091342
fatty acids of epidermophyton floccosum (harz) langeron and milochevitch. 19761004524
miconazole in the treatment of superficial mycoses.miconazole nitrate (2%) cream was evaluated in the treatment of superficial mycoses. out of 116 patients having multiple clinical diagnoses, 66 cases were found to be positive by culture. species of trichophyton were the predominant etiological agents (in over 60%) followed by candida species (20%) and epidermophyton floccosum (15%). all the cases selected for study were followed up to a period of 4-18 months. a cure rate of 94.6 per cent was observed in all the cases where causal organisms were ...1976967228
studies on the biological effects of deuteriated organic compounds. ii. morphological changes of epidermophyton floccosum exposed to perdeuteriated n-hendecanoic acid studied with interference contrast and scanning electron microscopy.in order to visualise the morphological changes of epidermophyton floccosum associated with exposure to perdeuteriated n-hendecanoic acid, the architecture of the dermatophyte was investigated by means of interference contrast and scanning electron microscopy. the morphology of mycelia grown on substrate containing perdeuteriated n-hendecanoic acid, or the unlabelled analogue, was compared. the perdeuteriated n-hendecanoic acid produced a characteristic undulant effect of the hyphae. the charact ...1976967224
contribution to the study on fatty acids of epidermophyton floccosum.the total lipid content of a dermatophyte, epidermophyton floccosum, grown under controlled environmental conditions, varies with growth stage and represents 7.0 to 19.8% of the dry weight. the main lipid classes, determined by quantitative thin-layer chromatography, were: triglycerides, free fatty acids, sterols and phospholipids. the fatty acid composition was established with the aid of combined gas chromatography-mass spectrometry. the major components, linoleic, palmitic and stearic acids r ...19751217274
production of elastase, urease and sulphatase by epidermophyton floccosum (harz) langeron et milochevitch (1930). 1977865508
ringworm on the scalp due to epidermophyton floccosum. 1977862222
[clinical peculiarities of mycoses caused by epidermophyton floccosum]. 19751231370
pattern of dermatophyte infection in singapore.dermatophyte infection is the fourth commonest skin disorder seen in the national skin centre in singapore. a prospective study was carried out from june 1990 to march 1991 to determine the epidemiology and pattern of dermatophyte infections seen in this centre. two hundred patients who had a clinical diagnosis of dermatophyte infection and confirmed by direct microscopy were included into the study. cultures for dermatophyte were done on sabouraud's dextrose agar with chloramphenicol and cycloh ...19921295417
dermatomycoses among industrial workers in cross river state, nigeria.a survey of dermatomycoses was carried out amongst industrial workers in three different factories during the period 1987-1988. a total of 194 workers were screened, out of which 54 proved to be mycologically positive by microscopy and/or culture. incidence was apparently highest amongst workers in a cement factory (calcemco, 33.3%) followed by those in a wood factory (seromwood, 30.8%) and a rubber factory (crel, 26.2%). pityriasis versicolor was the predominant clinical type of dermatomycosis, ...19921302813
occurrence of keratinolytic fungi and related dermatophytes in soils in cairo, egypt.120 soil samples collected from various sites of cairo were processed for the isolation of keratinophilic fungi by "tokava" hair baiting technique. 22 species belonging to 6 genera were isolated viz.: chrysosporium tropicum, c. indicum, c. keratinophilum, c. queenslandicum, c. merdarium, c. anamorph of arthroderma curreyi, c. pannicola, c. lobatum, c. anamorph of renispora flavissima, c. pseudomerdarium, microascus mangini, malbranchea gypsea, ml. state of uncicarpus reesii, ml. state of coccidi ...19921380752
antifungal activity of meridine, a natural product from the marine sponge corticium sp.meridine [1], a polycyclic alkaloid derived from the marine sponge corticium sp., was found to inhibit the growth of candida albicans and cryptococcus neoformans. activity was also observed against trichophyton mentagrophytes and epidermophyton floccosum. studies of the mechanism of action of this agent have shown an inhibition of nucleic acid biosynthesis.19921479383
once-weekly oral doses of fluconazole 150 mg in the treatment of tinea corporis/cruris and cutaneous candidiasis.ninety-five adult out-patients with tinea corporis and/or tinea cruris participated in a multicentre open non-comparative study investigating the safety and efficacy of 1-4 once-weekly doses of oral fluconazole 150 mg. trichophyton rubrum was isolated most frequently (67 of 86 mycologically evaluable patients). a mean of 2.6 doses of fluconazole was administered; patients infected with candida albicans or epidermophyton floccosum required an average of 2 doses compared to 3-4 doses in patients i ...19921486705
[shifts in the species spectrum of mycoses in the netherlands from 1970-1990].a review is presented of yeast and mould infections occurring in humans in the netherlands. the occurrence of the dermatophytes trichophyton rubrum and t. mentagrophytes tends to increase, while microsporum canis and particularly epidermophyton floccosum have become less common. the yeast candida glabrata is particularly often involved in infections of the urinary tract. candida krusei, c. parapsilosis and c. tropicalis have become less significant. remarkable differences are found between the s ...19921557162
dermatophytosis of children in kuwait.five hundred fifty-six children constituted 39.5% of total smear- and culture-positive cases of dermatophytosis and 0.6% of the total new dermatology outpatients seen over a period of five years. males outnumbered females. the youngest child was a 20-day-old neonate (age range 20 days-12 yrs) with a peak of fungal infections seen in patients between 4 and 6 years of age. microsporum canis was the most prevalent (70.5%) species, followed by trichophyton violaceum, microsporum audouinii, trichophy ...19921574472
[in vitro antifungal activity of itraconazole, a new triazole antifungal agent, against clinical isolates from patients with dermatomycoses].in vitro antifungal activities of itraconazole (itz), a triazole antifungal agent, against clinical isolates obtained from patients with superficial and subcutaneous mycoses were examined using the agar dilution method on casitone agar. the clinical isolates tested were 7 species and 263 isolates including trichophyton mentagrophytes (104 isolates), trichophyton rubrum (103 isolates), microsporum canis (3 isolates), epidermophyton floccosum (2 isolates), candida albicans (32 isolates), malassezi ...19911652655
dermatophytoses in cusco (peru).a total of 90 cases of suspected dermatophytoses was observed over a period of 9 months in the city of cusco (peru) and in its environs. the age groups most commonly infected were 1-10 and 11-20 year old. the most common tineae diagnosed were tinea capitis (13.3%) and tinea unguium (11.1%). only four species of dermatophytes were isolated: microsporum canis (52.4%), trichophyton mentagrophytes (35.7%), tr. rubrum (9.5%) and epidermophyton floccosum (2.4%). dry weather, low temperature and high a ...19911749399
15-year survey of tinea faciei in the adult.in a series of 100 adults with tinea faciei various dermatologic manifestations were mimicked, viz.: discoid lupus erythematosus in 52 patients, lymphocytic infiltration in 15, seborrheic dermatitis in 11, rosacea in 8, contacts dermatitis in 7, polymorphous light eruption in 4 and granuloma faciale in 3. trichophyton rubrum was isolated in 78% of the respective cases, other isolated organisms being microsporum canis (13 cases), trichophyton violaceum in 6, trichophyton mentagrophytes (asteroide ...19882971583
prevalence of superficial mycoses in the aosta valley region of italy from 1984 to 1989.this report represents the results of the culture tests for fungi carried out in the aosta valley region of italy from 1984 to 1989. the pathological material consisted of cutaneous scales, hair and nails. it was possible to identify 91.8% of the isolates: out of these, 36.1% were dermatophytes, 21% were aspergillus spp, 15.6% deuteromycetes, 15% yeasts and 4.1% members of the family mucoraceae. the resulting data indicate that microsporum canis was the most wide-spread species (73.7%) among the ...19911795730
dermatophyte feet infection among students enrolled in swimming courses at a university pool.the aim of this study was to determine the prevalence of dermatophyte feet infection among students enrolled in swimming courses at a university swimming pool. tinea pedis infection was determined on two occasions. the first study took place on the first day of classes and the second on day twelve of swimming lessons. culture and koh examination of the interdigital skin scrapings of the left foot showed superficial foot infection with dermatophytes or candida albicans in 13.2% of the students (1 ...19911930469
novel broad-spectrum metal-based antifungal agents. correlations amongst the structural and biological properties of copper (ii) 2-acetylpyridine n4-dialkylthiosemicarbazones.copper(ii) complexes of the type [cu(l)x], where l = tridentate anion of 2-acetylpyridine n4-diethyl thiosemicarbazone and x = c1 or br, were screened against seven fungal strains pathogenic to man viz. aspergillus niger, aspergillus fumigatus, candida albicans, cryptococcus neoformans, tricophyton rubrum, epidermophyton floccosum and microsporum canis. the greater growth inhibition exhibited by the bromo complex can be explained on the basis of its lower cu(ii)/cu(i) redox couple and greater co ...19911931432
[in vitro antifungal activities of amorolfine against fresh isolates from patients with cutaneous mycosis].in vitro antifungal activities of amorolfine (mt-861), a new morpholine antifungal agent, were examined using an agar-dilution method, in comparison with those of 2 other antifungal agents, clotrimazole (ctz) and bifonazole (bfz), against 182 clinical isolates of trichophyton rubrum, trichophyton mentagrophytes, microsporum canis, and epidermophyton floccosum, which had been freshly isolated from a total of 182 cutaneous mycotic patients with various types of dermatophytes or cutaneous candidias ...19911960850
fungal infections of the nail.onychomycoses represent the most frequently seen nail diseases and are the most difficult to treat of all skin mycoses. they are rare in children and increase in incidence with age. most cases are caused by dermatophytes, in particular by trichophyton rubrum, less frequently by t mentagrophytes and epidermophyton floccosum. molds may secondarily infect nails already diseased; however, some are probably capable of primary invasion of nail tissues. yeasts, particularly candida albicans, are mainly ...19912018719
oxiconazole nitrate: pharmacology, efficacy, and safety of a new imidazole antifungal agent.oxiconazole nitrate (1%) cream became available in the united states in 1989 for the once-daily treatment of tinea pedis, tinea cruris, and tinea corporis. it has also proved valuable in the once-daily treatment of tinea (pityriasis) versicolor. in vitro oxiconazole is highly effective against many dermatophytes, including trichophyton rubrum, trichophyton mentagrophytes, trichophyton tonsurans, and epidermophyton floccosum. after application to the skin, oxiconazole is rapidly absorbed into the ...19912029718
review of dermatophytoses in galicia from 1951 to 1987, and comparison with other areas of spain.we have reviewed all the dermatophytoses diagnosed in galicia during four consecutive 9-year periods 1951-86 and 1987. from 4571 patients, we isolated 3351 fungal strains belonging, in decreasing order of frequency, to the following dermatophyte species: microsporum canis (25.5%), trichophyton rubrum (24.6%), t. mentagrophytes (21.4%), epidermophyton floccosum (11.8%), m. gypseum (5.2%), t. tonsurans (3.9%), t. verrucosum (3.1%), t. schoenlenii (2.5%), t. violaceum (1.2%), t. mengninii (0.3%), m ...19912034261
plants used in guatemala for the treatment of dermatophytic infections. 1. screening for antimycotic activity of 44 plant extracts.skin infections are common diseases in developing countries, of which dermatophytoses are of particular concern in the tropics, especially in infants. through ethnobotanical surveys and literature review 100 plants were detected as being used in guatemala for the treatment of dermatophytoses. of these, 44 plants were screened for in vitro activity against the most common dermatophytes (epidermophyton floccosum, microsporum canis, microsporum gypseum, trichophyton mentagrophytes and trichophyton ...19912056755
the growth of epidermophyton floccosum and e. stockdaleae at different temperatures.the ability of 17 strains of genus epidermophyton (15 strains belonging to epidermophyton floccosum, one to e. floccosum var. nigricans and one to e. stockdaleae) to grow at different temperatures (4 degrees c, 25 degrees c, 28 degrees c, 31 degrees c, 34 degrees c, 37 degrees c and 40 degrees c) was stated. the strains were inoculated on sabouraud dextrose agar and regularly controled over a period of 14 days when the plates were incubated at 25 degrees c, 28 degrees c, 31 degrees c, 34 degrees ...19902089257
[dermatophytosis in a urban setting: prospective study of 135 cases].during a period of one year all patients referred to the dermatology department with the diagnosis of dermatophytosis were studied to determine the incidence. etiology, and epidemiology of these infections in the northeast of madrid. we have evaluated the sensitivity and specificity of the direct examination with 10% koh with respect to the culture as well as the correlation between the clinical diagnosis and the result of the mycologic examination. the annual incidence was 8.4 cases per 10,000 ...19902152479
in vitro susceptibility of dermatophytes from munich to griseofulvin, miconazole and ketoconazole.various recent clinical isolates of trichophyton rubrum, trichophyton mentagrophytes, microsporum canis and epidermophyton floccosum from munich were subjected to antimicrobial susceptibility testing using the microdilution method. both azoles miconazole and ketoconazole were found to be more active than griseofulvin. comparatively high inhibitory concentrations of griseofulvin were especially found with tr. mentagrophytes. on the whole miconazole turned out to be even somewhat more effective th ...19902359418
fungi causing dermatophytosis in lagos, nigeria.dermatophytes of the genera trichophyton, microsporum and epidermophyton were isolated from 162 (41%) of 395 patients with clinical manifestations of ringworm infection reporting at the lagos university teaching hospital, lagos, nigeria between january 1986 and december 1987. of the 162 strains of fungi isolated, 120 (74.1%) were microsporum species and 7 (4.3%) were epidermophyton floccosum. superficial mycosis was most prevalent on the skin (59.3%), followed by that of the hairs (27.2%). infec ...19902364899
ultrastructural alterations in epidermophyton floccosum and trichophyton mentagrophytes exposed in vitro to protoanemonin.protoanemonin (pra) is an antimicrobial agent whose mechanism of action has not been clearly described. some evidence exists which indicates that the compound inhibits growth by interacting with microtubules (mts). in order to confirm this hypothesis, an ultrastructural study was undertaken in vitro on epidermophyton floccosum and trichophyton mentagrophytes, two dermatophytes which proved to be sensitive to the drug. a concentration of 1.25 x 10(-4) m (half-mic dose) for 48 h, caused a series o ...19902373022
[dermatophytosis caused by epidermophyton floccosum in a patient with aids]. 19892490439
forty four years of dermatophytes in a chicago clinic (1944-1988).data are presented on 39,270 cultures taken over a 44 year span (1944-1988) at the university of chicago's dermatology clinic. in the mid 1940's microsporum audouinii accounted for 60-80% of isolates. it gradually decreased over the next two decades and disappeared altogether in the 1970's. trichophyton rubrum, rare in the 1940's accounted for over 60% of isolates in the mid-1960's only to be overtaken by t. tonsurans. this species, not isolated till the mid 1950's, became and remains the domina ...19921406904
dermatophyte fungi in the guinea savannah region of nigeria and the changing phase of dermatophytosis in nigeria.approximately 8,000 patients with various skin diseases were seen at the ahmadu bello university teaching hospital, kaduna, nigeria between january 1983 and december 1986. 174 (2.2%) presented with features in which a clinical diagnosis of superficial fungal infection was made or suspected. 69 out of 190 (36.3%) of specimens taken from skin lesions or nails from these patients were mycologically positive. the fungi isolated were trichophyton rubrum (24.6%), tr. soudanense (13.0%), candida albica ...19892677715
[synthesis and antifungal activity of n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-alpha-substituted -1-(4-substi tuted) naphthalenemethanamines].thirty (e)- or (z)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-alpha-subst itu ted-1-(4-substituted)naphthalenemethanamines were synthesized for searching of more potent and less toxic antimycotic agents. all title compounds and most of the intermediates are new. results of preliminary biological tests showed that most of the title compounds exhibited activity against the common pathogenic fungi such as cryptococcus neoformnas, candida albicans, aspergillus fumigatus, cladosporium carrionii, sporo ...19892700413
clinical examinations with chinofungin spray and chinofungin powder.tolnaftate is effective in the local treatment of dermatophyte infections. it is recommended primarily in infections caused by trichophyton rubrum, trichophyton mentagrophytes, epidermophyton floccosum, microsporum canis and malassezia furfur. it may be useful as an adjuvant local therapy in chronic dermatophyte infections treated with griseofulvin.19892756514
foot infections due to hendersonula toruloidea and scytalidium hyalinum in coal miners.a total of 250 coal miners were screened for mycotic skin infections. sixty-six (34.8%) miners had clinical lesions on their feet which proved to be of mycotic etiology by direct microscopy and culture. hendersonula toruloidea, the commonest etiological agent, was the sole agent recovered from 23 (34.8%) of the positive cases and was also isolated from three (4.5%) cases of mixed infection with dermatophytes (two cases with trichophyton rubrum and one with trichophyton mentagrophytes var. mentag ...19892778576
fungal infection as a cause of skin disease in the eastern province of saudi arabia: prevailing fungi and pattern of infection.a total of 4,294 clinically suspected cases of dermatomycoses belonging to 26 different nationalities were examined between april 1984 and april 1988. fungi were demonstrated in routine potassium hydroxide/dimethyl sulfoxide mount in 3,814 cases (88.8%) and the etiology was determined by culture in 2,458 cases (57.2%). tinea versicolor was the predominant fungal infection (30.9% of all infections). onychomycosis and paronychia ranked second in prevalence (16.8%). candidal onychomycosis was the m ...19911803238
fungal infection as a cause of skin disease in the eastern province of saudi arabia: tinea corporis and tinea cruris.in the period between april 1984 and april 1988 a total of 4,294 clinically suspected cases of dermatomycoses were examined for causative fungi. of these cases 768 (17.9%) were suspected as tinea corporis (427 cases) and tinea cruris (341 cases). twenty two different nationalities were represented. both sexes were involved and the age range was 19 days to 70 years. of the 768 patients examined, 738 (96.1%) had their diagnosis confirmed by direct microscopy and in 631 of these positive cases the ...19911820522
a survey of dermatophytes from human patients in the united states from 1985 to 1987.a survey of dermatophytes isolated from patients seeking medical advice was made from 1985 to 1987 in the united states. the survey included 54 locations with data from 45 cities and one state. listing of the isolated dermatophytes and the frequency given by percentage of the total follows: trichophyton rubrum 54.8%, t. tonsurans 31.3%, t. mentagrophytes 6.0%, microsporum canis 4.0%, epidermophyton floccosum 2.0%, m. gypseum 0.6%, and t. verrucosum 0.2%. out of a total of 14,696 isolates m. audo ...19911875984
screening of some essential oils for their activities on dermatophytes.fifty-three essential oils were tested against three frequently occurring dermatophytes (epidermophyton floccosum, trichophyton mentagrophytes var. interdigitale, t. rubrum) by means of an agar dilution technique. the oils were selected at random and not on the basis of a supposed activity. a number of oils showed interesting activities, expressed as maximum inhibitory dilution values, against the dermatophytes used. at the highest dilution tested (1:3,200, vol/vol), one out of six oils was acti ...19883211701
role of fatty acids in regulation of membrane properties in epidermophyton floccosum. 19883243560
quantitative neutralization assay of fungicidal activity of disinfectants.a quantitative assay using a neutralization medium was developed to evaluate fungicidal activity of disinfectants. concentrated dey-engley neutralizing broth was used in this study and was demonstrated to inactivate various chemical agents within 5 min when disinfectant concentrations were reduced to specific levels. addition of this dey-engley broth to test tubes containing fungal cells and disinfectants permitted control of the various interactions times. subsequent concentration of the disinf ...19873300541
antimycotic effect in vitro of a detergent. fungicidal and fungistatic effect of the detergent and its components on trichophyton mentagrophytes. trichophyton rubrum and epidermophyton floccosum. 19644164955
studies in the epidemiology of tinea pedis. ix. tinea pedis and erythrasma in new patients at a chiropody clinic.the feet of 259 new patients at a chiropody clinic were examined for tinea pedis, onychomycosis, and erythrasma: 23% of men and 4% of women were infected by dermatophytes, and the nails of seven males were infected by non-dermatophytes. of 200 patients examined under wood's light 37% showed the coral-red fluorescence of erythrasma.of the 259 patients, 9.7% were infected by trichophyton interdigitale, 2.7% by t. rubrum, and 1.5% by epidermophyton floccosum. reasons are given, based on the method ...19684234612
a ten year survey of superficial mycoses in the tauranga district, bay of plenty.between 1 january 1976 and 31 december 1985, 4086 patients living in tauranga and its environs were examined mycologically. all were suspected of superficial cutaneous mycoses and the majority were referred by general practitioners. a total of 1085 pathogenic fungi were identified, an isolation rate of 27%. the main pathogens identified in order of frequency were--candida species; microsporum canis; trichophyton rubrum; malassezia furfur; epidermophyton floccosum; t mentagrophytes var interdigit ...19883357624
superficial fungal infections in the transvaal. a contemporary analysis of dermatophytoses in this region.an 8-year survey of patients from hospital clinics and private practices in pretoria seeking specialist dermatological advice for dermatophytoses revealed almost 500 cases, which were confirmed by mycological study. correlation of the data with other localities was made to illustrate the epidemiology for several common dermatophytes in the transvaal. trichophyton rubrum (27%) proved to be the most prominent dermatophyte, followed by t. mentagrophytes (23%), microsporum canis (19%), t. violaceum ...19883375906
[dermatophytes and immigration].an epidemiological study of dermatophytes was achieved during the years 1983-1984 in the mycology laboratory of saint-louis' hospital. immigrants represent an important part of the people who came to consult us: 28 per cent in 1983. the two most important immigrant peoples show different features: black african people, who were mass contaminated by tinea agents (trichophyton soudanense and microsporum langeronii), were not much contaminated by epidermophytic agents (trichophyton rubrum, trichoph ...19883389576
lipids of dermatophytes. iii. sterol-induced changes in the lipid composition and functional properties of epidermophyton floccosum.sterol supplementation, alone or in the presence of cerulenin, resulted in an increase in the total sterol content of epidermophyton floccosum. while the total phospholipid levels of e. floccosum exhibited only marginal changes with sterol supplementation, the fatty acid profiles of these phospholipids were highly varied. in the presence or absence of cerulenin, the oleic acid content of phospholipids were increased significantly by cholesterol supplementation, whereas linoleic acid levels were ...19883412123
epidermophyton floccosum endemic in the sauna of a trade school hostel. 19744437592
epidemiology and clinical features of dermatomycoses and dermatophytoses.dermatophytosis, candidosis and pityriasis versicolor account for the majority of fungal skin diseases in denmark and are seen in 8% of patients with dermato-venerological problems. in children, zoophilic species like microsporum canis (from cats), trichophyton (t) verrucosum (from cattle) and t. mentagrophytes granulare (from rodents) are the common causes of dermatophytosis and are seen in approximately 15% of all cases. anthropophilic species are the main cause of dermatophytosis in adults an ...19863459342
control of tinea pedis in a swimming bath.random samples of the weekly entry of bathers to a swimming pool were examined for tinea pedis and verruca before and at intervals after the supply of individual sachets of foot powder to all bathers.over three and a half years the overall incidence of tinea pedis decreased from 8.5% to 2.1%, and in adult males it decreased from 21.5% to 6.9%. the incidence of infection with trichophyton mentagrophytes var. interdigitale decreased from 5.3% to 0.5%, and the incidence of infection with t. rubrum ...19744833961
[changes in skin reactivity of guinea pigs following sensitization with antigens of the dermatophytic mold epidermophyton floccosum]. 19674869604
[course of systemic reaction in sensitized and control rabbits following intravenous administration of an antigen isolated from a culture of epidermophyton floccosum]. 19674876357
production of antibiotics by epidermophyton floccosum. 2. microflora in epidermophyton-infected skin and its resistance to antibiotics produced by the fungus. 19684906403
in vitro studies of antidermatophytic activity of juliflorine and its screening as carcinogen in salmonella/microsome test system.juliflorine, an alkaloid from prosopis juliflora, was tested for its antifungal activity against the freshly isolated cultures of dermatophytic fungi and its inhibitory effect was compared with that of griseofulvin. the results indicated that the minimum inhibitory concentration (mic) of juliflorine against trichophyton rubrum, trichophyton violaceum, trichophyton mentagrophytes, trichophyton tonsurans, trichophyton megninii, trichophyton gallinae, microsporum canis, microsporum nanum, microspor ...19863513775
initiation of dermatophyte pleomorphic strain sporulation by increased aeration.a normally asporogenous pleomorphic strain of microsporum gypseum was induced to sporulate by controlled aeration and dehydration. aeration of the pleomorphic strain under optimal cultivation conditions caused the initiation of a sporulation cycle with equivalent growth parameters and percentage intracellular water loss as the wild-type strain. initiation of sporulation was not due to alteration of the medium's nutrient concentration or consistency, concentration of fungal growth by-products, or ...19725086905
[familial infection with epidermophyton floccosum]. 19715136805
[experimental sensitization of guinea pigs and rabbits with antigen prepared from epidermophyton floccosum]. 19675244241
production of antibiotics by epidermophyton floccosum. 5. relation between the "epidermophyton factor" (epf) and some steroid antibiotics, particularly fucidin. 19705273521
[boarding school epidemic of an erythrasma-like inguinal tinea caused by epidermophyton floccosum and trichophyton mentagrophytes]. 19715577537
reversal of cerulenin-induced inhibition of phospholipids and sterol synthesis by exogenous fatty acids/sterols in epidermophyton floccosum.cerulenin, a specific inhibitor of fatty acids and sterol biosynthesis inhibited the growth of epidermophyton floccosum, which was reversed when growth medium was supplemented with palmitic acid and sterols. unsaturated fatty acids partially restored the growth. cerulenin inhibited both phospholipid and sterol biosynthesis (60-70%) at the minimum inhibitory concentration (0.5 microgram/ml) as demonstrated by [32p]orthophosphoric acid and [14c]acetate incorporation into the respective lipids. cer ...19873651491
epidermophyton floccosum infecting the langugo hair. 19655831544
isolation of keratinophilic fungi from floors in roman kindergarten and secondary schools.we examined the dust collected from the floors of forty classrooms, twenty in kindergarten schools (children aged 2-5) and twenty in secondary schools (students aged 11-14) in order to determine the diffusion of keratinophilic fungi in respect to such different factors as human presence and children's age. in the kindergarten schools 268 colonies of keratinophilic fungi were isolated: 50 were microsporum, 6 trichophyton and 212 chrysosporium species. members of the chrysosporium genus were found ...19863724835
antimicrobial activity of protoanemonin, a lactone from ranunculaceous plants.protoanemonin, a component of ranunculus bulbosus, was tested as an antifungal agent on selected strains of dermatophytes and yeasts. the minimum inhibitory concentrations ranged from 2.0 to 7.5 x 10(-4) m and the minimum lethal concentrations from 3.8 x 10(-4) m to greater than 1.0 x 10(-3) m. the most sensitive dermatophyte tested was epidermophyton floccosum, and the most sensitive yeast rhodotorula glutinis. the effects of different culture media and of light on the sensitivity of rhodotorul ...19873587338
[analysis of the occurrence of mycotic infections induced by epidermophyton floccosum (harz) langeron et milochevitch (1930) in the past 20 years]. 19751117890
experimental and clinical investigation on oxiconazole.a new antimycotic imicazole drug, oxiconazole, used both in vitro and in vivo in the treatment of 212 cases of tinea corporis, tinea cruris and tinea pedis is reported. in vitro, it shows marked antimycotic effect against 24 strains of pathogenic fungi except those of wangiella dermatitides and 3 strains of aspergilli. the minimal inhibition concentration (mic) to epidermophyton floccosum and candida guilliermondi are 1 microgram/ml and 0.5 microgram/ml. the cure rate of 2% cream of oxiconazole ...19892517622
[in vitro study of the antifungal activity of two chlorine derivatives to be used in antisepsis].the activity of two chlorine derivates, sodium hypochlorite in water solution with nacl (product a) and electrolytic chloroxidant (product b) has been tested in vitro against potentially human pathogenic fungi (aspergillus niger, aspergillus fumigatus, microsporum gypseum, candida albicans, cryptococcus neoformans, trichophyton mentagrophytes, microsporum canis, epidermophyton floccosum, trichophyton rubrum, sporotrix schenkii). for a. niger, the relation of the two compounds has also been consi ...19892483652
a survey of dermatophytes isolated from human patients in the united states from 1982 to 1984.a survey of dermatophytes isolated from patients seeking medical advice was made from 1982 to 1984 in the united states. the survey included 59 locations with data from 49 cities and one state. listing of the isolated dermatophytes and the frequency given by percentage of total follows: trichophyton rubrum 46.8%, t. tonsurans 33.3%, t. mentagrophytes 10.1%, microsporum canis 4.5%, epidermophyton floccosum 3,5%, m. gypseum and t. verrucosum both 0.7%, m. audouinii and t. terrestre both 0.1%, and ...19873587334
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