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pyogenic liver abscess caused by streptococcus milleri.three clinically typical cases of multiple pyogenic liver abscesses are presented. in all three cases streptococus milleri was isolated from the pus and in two cases it was isolated from blood cultures also. the patients were successfully treated by surgical drainage and antibiotics.197547082
letter: streptococcus milleri liver abscesses. 197655933
interactions between human serum proteins and oral streptococci reveal occurrence of receptors for aggregated beta 2-microglobulin.a total of 31 strains of oral streptococci representing streptococcus mutans, streptococcus sanguis, streptococcus mitior, streptococcus salivarius, and streptococcus milleri were tested for possible binding of human immunoglobulins g, g1, g2, g3, g4, a1, a2, m1, and m2 and haptoglobin, hemoglobin, fibrinogen, and aggregated beta 2-microglobulin. radiolabeled beta 2-microglobulin in aggregated form showed affinity for 20 of the 31 strains tested. binding activity for the protein was found in str ...197990015
dental caries induced by streptococcus milleri. 1977270502
streptococcus milleri (guthof) and streptococcus mutans in the mouths of infants before and after tooth eruption. 1978299020
bacteriology of abscesses of the central nervous system: a multicentre prospective study.pus from 46 patients with abscesses of the central nervous system (cns) was examined for bacteria; bacteria were found in all patients. streptococci were isolated from 36 patients and most isolates were streptococcus milleri, lancefield group f, ottens and winkler type o iii. staphylococci were isolated from nine patients, organisms of the bacteroides group from 11, proteus spp from seven, klebsiella aerogenes from one, and haemophilus aphrophilus from one. pure cultures predominated over mixed ...1977336141
occurrence and cultural features of streptococcus milleri in various body sites.an investigation was made into the habitat of commensal strains of streptococcus milleri. these showed distinctive patterns of cultural features, dependent on their sites of origin, which were compared with those prevalent in strains grown from the appendix, 'anal' lesions, and bartholin's abscesses. a biotype, which showed a marked affinity for the vagina and produced acid from raffinose and melibiose, was identified.1979512036
mycotic aneurysm of the abdominal aorta due to streptococcus milleri. 1979582607
serious infections caused by streptococcus milleri.viridans streptococci continue to be the most common etiologic agents in bacterial endocarditis. the spectrum of diseases other than endocarditis caused by these organisms, however, has received sparse attention. moreover, little clinical information is available concerning the individual viridans streptococcal species. during the 16 months of this study, one species of viridans streptococci, streptococcus milleri, caused a surprising number of clinically significant suppurative infections. clin ...1978645741
brain abscess due to streptococcus mg-intermedius (streptococcus milleri).three cases of brain abscesses due to streptococcus mg-intermedius are reported, and the literature pertaining to this subject is reviewed. the importance of careful and complete identification of these etiological agents of infection is stressed. the clinical presentation, the origin of s. mg-intermedius producing brain abscess, and its relation to hepatic abscesses and endocarditis are discussed.1978670377
expression of streptococcus mutans gtf genes in streptococcus milleri.the streptococcus mutans glucosyltransferase (gtf) genes gtfb and gtfc were ligated into escherichia coli-streptococcus shuttle plasmids and introduced into streptococcus milleri. gtfb transformant ksb8 formed an s. mutans-like rough colony on mitis salivarius agar and expressed an extracellular gtf-i, of 158 kda, and two cell-bound gtf-is, of 158 and 135 kda. gtfc transformant ksc43 formed a semirough colony on mitis salivarius agar and expressed primarily an extracellular gtf-si, of 146 kda, a ...19921377183
primary abscess of the psoas muscle caused by streptococcus milleri. 19921445991
detection of diacetyl (caramel odor) in presumptive identification of the "streptococcus milleri" group.the caramel odor associated with the "streptococcus milleri" group was shown to be attributable to the formation of the metabolite diacetyl. levels of diacetyl in the 22- to 200-mg/liter range were produced by 68 strains of the "s. milleri" group; apart from one strain of streptococcus mutans, all 92 other strains of streptococci belonging to 12 species produced < 13 mg of diacetyl per liter. quantitation of diacetyl levels from cultures of streptococci is suggested as a rapid presumptive test f ...19921452678
susceptibility of sixty-five non-oral clinical isolates of the streptococcus milleri group to seven antimicrobial agents.antimicrobial susceptibilities of sixty-five non-oral streptococcus milleri group clinical isolates to penicillin, gentamicin, lincomycin, ampicillin, chloramphenicol, tetracycline and erythromycin were determined by an agar dilution method. all strains were penicillin-sensitive (mic < or = 0.031 microgram/ml) and the majority (64/65) were susceptible to erythromycin (mic < or = 0.125 microgram/ml). low-level resistance to gentamicin was observed, and the majority of strains possessed an mic of ...19921453983
the endodontic microflora revisited.the microbial flora of 35 dental root canals were examined, taking care to maintain the viability of obligate anaerobes which accounted for 45% of total isolations, while streptococcal species accounted for 24% of the total species isolated. individual root canals yielded a maximum of eight bacterial species. a total of 40 different species was isolated of which the most prevalent were the facultative anaerobe streptococcus sanguis and the obligate anaerobe, peptostreptococcus micros (both in 23 ...19921479923
restricted distribution of streptococcus milleri carbohydrate type antigens amongst other viridans streptococci.the distribution of oral streptococcus milleri carbohydrate type antigens in other viridans streptococcus species was examined. rantz-randall extracts of cells of the test strains grown in broth containing glucose were allowed to react with typing or grouping antisera for s. milleri serotypes a-k, or lancefield groups a-g and k. of 93 strains comprising more than 12 streptococcal species that included s. mutans and s. sanguis complexes, only 15 s. salivarius strains and one s. mitis strain were ...19921518038
effects of arginine and arginyl-l-arginine on the glucose-mediated ph fall of streptococcus rattus and streptococcus milleri (short communication). 19921521307
streptococcus milleri group: renewed interest in an elusive pathogen.the following review examines the bacteriological characteristics, epidemiology, pathogenicity and antimicrobial susceptibility of the "streptococcus milleri group". "streptococcus milleri group" is a term for a large group of streptococci which includes streptococcus intermedius, streptococcus constellatus and streptococcus anginosus. usually considered commensals, these organisms are often associated with various pyogenic infections including cardiac, abdominal, skin and central nervous system ...19921526231
differentiation of species in human beta-haemolytic group g streptococci using immunoglobulin fc fragment receptor.to assess the ability of human immunoglobulin fc fragment binding activity to differentiate human biotype large colony group g streptococci from the group g "streptococcus milleri group".19921556232
septic streptococcus milleri prepatellar bursitis.the osteoarticular affinity of streptococcus milleri has only recently been recognized. we report a case of septic prepatellar bursitis caused by this pathogen. the recent literature concerning osteoarticular involvement by s. milleri is reviewed.19921582108
etiology and antibiotic susceptibility of bloodstream streptococcus sp.249 episodes of streptococcus bacteraemia in hospitalized patients were evaluated for both clinical and microbiological features. specification of the isolates demonstrated that infective endocarditis was predominantly associated with streptococcus sanguis and streptococcus bovis whereas streptococcus pyogenes and streptococcus milleri were the most common cause of local and/or systemic infections. in vitro-susceptibility tests towards 9 selected antibiotics proved that beta-lactam antibiotics a ...19921611209
[pansinusitis of the face caused by streptococcus milleri with cerebral thrombophlebitis after naso-sphenoid surgery of the pituitary gland].the authors report a patient operated on trans-nasosphenoidally for a pituitary adenoma (cushing's disease) in whom a severe infection occurred with cavernous thrombophlebitis responsible for neurological complications.19921620434
fatal basilar vasculopathy complicating bacterial meningitis.bacterial meningitis complicated by thrombosis, vasculitis, and aneurysm formation affecting both small and distal branches of cerebral vessels has been well described. involvement of major cerebral vessels is rare and has only been documented late in the course of disease.19921636194
[severe infections due to streptococcus milleri in children].streptococcus milleri (s. milleri) is found in healthy individuals in the mouth, nasopharynx, throat, vagina and in feces, and has been reported to be isolated from several infectious diseases in man, particularly from abscess in various parts of the body. we report two cases of severe infections due to s. milleri isolated from subdural abscess and pleural empyema. [case 1] 13 year old boy who had been healthy until he was noticed to have meningeal signs and was diagnosed as left subdural absces ...19911680938
spinal sepsis due to streptococcus milleri: two cases and review.we have recently cared for two patients with spinal sepsis secondary to infection with streptococcus milleri. one patient had a spinal epidural abscess and the other had meningitis as well as a spinal subdural empyema. a review of the english-language literature revealed only two previously reported cases of spinal epidural abscess due to s. milleri and no cases of spinal subdural empyema due to s. milleri. we report two cases of spinal sepsis due to s. milleri and discuss pertinent literature.19911681578
glucanase-producing organisms in human dental plaques.selective media were used to isolate a wide range of bacteria from sixty human dental plaques. glucanase activities of the isolates were determined on dextran- and starch-containing media. all sixty samples of dental plaque yielded some colonies showing amylolytic and dextranolytic activities. the glucanase-producing organisms comprised 20% of the isolates. of these 38% were gram-positive rods, 27% gram-positive cocci, 28% gram-negative rods and 7% were gram-negative cocci. the cultural groups m ...19901691432
streptococcus intermedius, streptococcus constellatus, and streptococcus anginosus (the streptococcus milleri group): association with different body sites and clinical infections.the associations of streptococcus intermedius, s. constellatus, and s. anginosus (the three species of the s. milleri group) with clinical infections and sites of isolation were investigated by using a simple biochemical scheme to identify a collection of 153 clinical isolates. s. intermedius was associated with abscesses of the brain and liver, while both s. anginosus and s. constellatus were isolated from a wider range of sites and infections. s. anginosus strains predominated in both genitour ...19921734062
epidural abscess due to streptococcus milleri and bifidobacterium species. 19911753128
[bacteriological examination of infections in the field of oral surgery].etiology of bacterial infections in the field of oral surgery was studied. a total of 270 samples collected from patients with encapsulated abscess in their oral cavities was examined and bacteria were isolated from the 244 samples (90.4%). the following results were found; 1) organisms more than one from one sample were frequently isolated from cases with parodontitis, pericoronitis and gnathitis. isolation of anaerobic bacteria was common (54.2%). 2) streptococcus milleri and streptococcus san ...19911791332
antibacterial activity of cefpodoxime in comparison with cefixime, cefdinir, cefetamet, ceftibuten, loracarbef, cefprozil, bay 3522, cefuroxime, cefaclor and cefadroxil.the new oral cephalosporins cefpodoxime, cefixime, cefdinir, cefetamet and ceftibuten demonstrate enhanced activity against enterobacteriaceae susceptible to the established compounds as well (e.g. cefuroxime, cefaclor, cefadroxil). in addition, cefpodoxime, cefixime, cefdinir, cefetamet and ceftibuten include in their spectrum species hitherto resistant to oral cephalosporins (proteus vulgaris, providencia spp., yersinia enterocolitica). besides, the majority of these compounds demonstrate rele ...19911800377
clinical and bacterial features of infections caused by streptococcus milleri.the clinical and bacteriological features of 51 infections due to streptococcus milleri observed in 43 patients over a 2-year period were reviewed. clinical syndromes included bacteremia in 6 cases, endocarditis in 4 cases, cellulitis and subcutaneous abscesses in 8 cases, pleural empyema in 8 cases, brain abscesses in 5 cases, abdominal infections in 5 cases, and other miscellaneous infections in 15 cases. an underlying condition was associated with infection in 33/43 patients (77%). s. milleri ...19911815325
a modified mitis salivarius medium for a caries diagnostic test.a new medium, mskb, composed of mitis salivarius agar base, sorbitol, kanamycin sulfate and bacitracin, has been developed that is more selective for recovery of mutans streptococci (mutans) than the so called mitis salivarius bacitracin (msb) medium. msb and mskb were compared for recovery and selectivity of mutans by plating saliva samples as well as pure cultures on both media. sixty saliva samples were plated and counted for mutans and non-mutans colonies. thirty-six samples had greater numb ...19911820563
[studies on clinical significance of "streptococcus milleri group" in respiratory infections]."streptococcus milleri group" are the part of the indigenous oral flora, and they are proposed to contain three distinct species: streptococcus anginosus, streptococcus constellatus, and streptococcus intermedius. though not included in the approved lists of bacterial names, "s. milleri group" are regarded as the causative organisms of suppurative infections, such as oral abscess, brain abscess, lung abscess and empyema. i have studied the clinical significance of the "s. milleri group" in respi ...19911791343
[a case of remarkable effect of clindamycin in nasal septum abscess caused by streptococcus milleri].we encountered a 14-year-old male patient with a destructive abscess of nasal septum, caused by streptococcus milleri. he was successfully treated with clindamycin in combination with surgical intervention. we emphasized the significance of streptococcus milleri as a causative agent for abscess formation, and clindamycin should be considered as a first choice of antibiotics against streptococcus milleri infection.19911791336
pyogenic arthritis caused by streptococcus milleri in a nonimmunocompromised host.we describe a case of pyogenic arthritis caused by s. milleri (s. anginosus) in a non-immunocompromised host. no other septic focus was found. s. milleri is now widely recognized as an important cause of pyogenic infection, though it eluded suspicion for many years. the rarity of reports of articular infections by s. milleri might be due to problems associated with its recognition.19911856820
frequent hospital admissions for bacterial infections among aboriginal people with diabetes in central australia.to determine hospital-based morbidity and mortality from bacterial infections among aboriginal people with diabetes in central australia.19911875833
effects of pulsing with xylitol on mixed continuous cultures of oral streptococci.continuous culture is a means whereby organisms can be grown at rates approaching those occurring naturally. moreover, the effect of adding transient excesses of various nutrients to the culture vessel ('pulsing') simulates the effect of dietary challenge on dental plaque organisms. mixed cultures of streptococcus mutans t8 and streptococcus milleri b448 were grown glucose-limited in a chemically defined medium under an atmosphere of 5 per cent carbon dioxide in nitrogen, at a dilution rate of d ...19911877919
thoracic empyema due to streptococcus intermedius.with improved laboratory identification procedures, streptococcus milleri (intermedius) is becoming recognized as an important human pathogen with the potential to form abscesses in a wide range of organs. the occurrence of a rapidly progressive and toxic empyema due to this organism in an otherwise healthy young adult without a predisposing lower respiratory tract infection allows us to examine the possibility that this microbe may be a significant but frequently unrecognized cause of adult emp ...19911748832
subdural and epidural empyema: diagnostic and therapeutic problems.a clinical and microbiological review of cases of subdural and epidural empyema.19911674582
[fever, headache and paralysis of the left leg].a 17 year old man was hospitalized because of fever, headache and a paresis of his left leg. radiologic findings demonstrated a subdural interhemispheric empyema on the right side as a complication of ipsilateral pansinusitis. streptococcus milleri was cultured as the only pathogen from maxillary sinus suppuration. pathogenesis and therapy of subdural empyema are discussed. cure was achieved with ceftriaxone, flucloxacilline and ornidazole during one week followed by ceftriaxone as monotherapy d ...19911674167
a numerical taxonomic study of the "streptococcus milleri" group based upon conventional phenotypic tests and pyrolysis mass spectrometry.clinical strains presumptively identified as streptococcus milleri (60), and blind coded collection strains (21) were characterised in conventional tests and pyrolysis mass spectrometry. comparison of the clusters found by these two approaches revealed five clearly distinct centres of variation. three corresponded to the dna homology groups suggested by whiley and hardie (1989) as representing the species s. anginosus, s. intermedius and s. constellatus; a fourth comprised three lancefield group ...19921548689
lactose-sensitive and -insensitive cell surface interactions of oral streptococcus milleri strains and actinomyces.of 158 oral streptococcus milleri strains, 46 exhibited cellular coaggregation with the reagent strains of the actinomyces coaggregation groups a, b, and/or e. all but 1 of the 33 serotype b, e, f/f, and k/g strains belonged to streptococcus coaggregation group 2, and only 14 strains of limited seroclasses (g, i, lancefield group f, or untypeable) appeared to be members of group 5, 3, or 4 (10, 3, and 1 strain, respectively). thus, s. milleri infrequently exhibits lactose-inhibitable coaggregati ...19911987061
serological and biological characteristics of "streptococcus milleri" isolates from systemic purulent infections.ninety-one streptococcus milleri strains isolated from various systemic purulent lesions of 68 patients were examined by physiological and serological tests. most strains formed a smooth colony (66 strains), did not form spontaneous aggregation of cells in bhi broth culture (79), were non-beta-haemolytic (alpha-35 or non-41), and belonged to biotype ia (49) or ib (34) and to api taxa s. milleri i (41) or ii (38). almost all of the beta-haemolytic strains as well as two-fifths of the non-beta-hae ...19921548688
[pyogenic liver abscess caused by streptococcus milleri].streptococcus milleri is a facultative anaerobic pathogen of the viridans group associated with serious suppurative infections, mainly abscesses. we saw 3 cases of liver abscess due to this organism in 1990 in women aged 43, 59 and 67 years, respectively. the coccus was grown from blood cultures in 2 of the cases and from abscess drainage in the 3rd. the importance of prompt diagnosis of liver abscess by means of ct and ultrasonography is stressed. conservative treatment consists of ct-guided pe ...19921526542
[liver abscess caused by streptococcus milleri]. 19921493888
use of rapid carbohydrate utilisation test for identifying "streptococcus milleri group".a short series of biochemical and serological tests were developed for the rapid presumptive identification of "streptococcus milleri group" isolates. one hundred and seventy seven streptococcal isolates were recovered from the mouths of 10 out of 12 healthy adult volunteers by use of a simple sampling procedure and a single selective medium. in all, 127 oral "s milleri group" isolates were identified by biochemical and serological tests, confirming the indigenous nature of these streptococci in ...19912030154
streptococcus milleri and complex groin abscesses in intravenous drug abusers.intravenous drug abuse is an increasing problem. septic complications occur frequently at the injection site, especially in the groin where large abscesses around the femoral vessels can threaten life or limb. we report four patients with extensive or complex groin abscesses following attempted self-injection into the femoral vein. streptococcus milleri was cultured from all of these abscesses and prompted a review of the isolation of this organism in this hospital.19921411480
the bacteriology of brain abscess: a local experience in malaysia.31 cases of intracranial abscess seen over a period of 10 years showed a peak incidence in the second and third decades of life with a male preponderance. tetralogy of fallot and other congenital cyanotic heart diseases were the predominant associated factors (32%). the commonest site of infection was the frontal lobe. gram-stained smears of pus proved to be extremely useful. the majority of the organisms (82%) were either microaerophilic or anaerobic bacteria with streptococcus milleri being th ...19902091359
serogrouping of oral streptococcus intermedius.employing twenty fresh oral isolates of streptococcus intermedius, studies were carried out to characterize serological relations among the isolates and also between the isolates and the strains of bacterial species closely related to s. intermedius. the rantz-randall extracts from the cells were used as antigens. the anti-rabbit serum raised against s. intermedius atcc 27335t reacted with the cell extracts from only three strains of the isolates, which were designated serogroup i strains. the o ...19902111871
immunochemical characterization of type i carbohydrate antigen of "streptococcus milleri" (streptococcus anginosus).type-specific carbohydrate antigen of the serotype i "streptococcus milleri" was extracted with trichloroacetic acid from purified cell walls of the type strain k39k. the extracts were then purified by chromatography on deae-sephadex a-25 and sephadex g-100 columns. the purified serotype i carbohydrate antigen produced a single precipitin band against its homologous type-specific antiserum, which fused with the band produced by the autoclaved extract of the type strain cells. the serotype i anti ...19902124490
is candidiasis the true cause of vulvovaginal irritation in women with diabetes mellitus?vulvovaginitis is common in diabetic women and is often treated with antifungal agents on the assumption that the causative organism is candida albicans. in a survey of 100 consecutive diabetic women attending a diabetes clinic 36 had complained to their general practitioner about vulvovaginal irritation during the past three years and 26 were treated with antifungal agents without a vaginal examination or swabs being taken. in a separate study 27 post-menopausal women with non-insulin dependent ...19902131794
sinusitis-induced subdural empyema.over a 17 year period, 1975-91, 10 children were managed who had sinusitis-induced subdural or extradural empyema. their ages ranged from 6 to 14 years, with a mean of 11 years. all presented with worsening headaches, fever, vomiting, all had neurological abnormalities, and all had symptoms or signs suggestive of sinusitis. initial computed tomography gave normal results in five cases and the empyema was diagnosed on the second or third scan. all patients had symptoms for at least one to two wee ...19921362638
de novo glucan synthesis by mutants streptococcal glucosyltransferases present in pellicle promotes firm binding of streptococcus gordonii to tooth surfaces.adherence of 3h-labelled cells of streptococcus gordonii and streptococcus milleri to artificial pellicles prepared from saliva supplemented with glucosyltransferases from mutants streptococci was examined using a new assay for sucrose-dependent cell-to-pellicle attachment. results indicate that s. gordonii, but not s. milleri, could attach tightly to hydroxylapatite surfaces through de novo glucan synthesis by mutants streptococcal glucosyltransferases present in the experimental salivary pelli ...19921327954
culture-positive thoracic empyema in adults.twenty-nine adult patients with culture-positive thoracic empyema were seen at the university hospital kuala lumpur from 1984 to 1988. cough, fever, chest pain, dyspnoea and weight loss were the common presenting symptoms. the empyema in 16 patients was associated with primary bronchopulmonary infections, nine occurred following thoracentesis of culture-sterile pleural effusions, two occurred as post-thoracic surgery complications, one following a subdiaphragmatic abscess and one as a result of ...19902152022
interest of gallium hepatic scintigraphy in hepatic abscess: a case study.the interest of 67ga-citrate scintigraphy in the diagnosis of hepatic abscess is illustrated by a study of a 56-year-old man, who was admitted to the hospital for upper abdominal pain. ultrasound (us) and x-ray ct scan examinations suggested the presence of a liquid mass, the origin of which was unclear. liver scintigraphy with 67ga-citrate disclosed a lacunar zone surrounded by a rim of increased uptake, an image strongly suggestive of abscess or necrotic tumor. a us-guided needle aspiration of ...19902173319
the microbiology of periapical granulomas.of the 16 periapical granulomas studied, 14 (88%) yielded a positive growth when homogenized and cultured. the concentration of colony-forming units per milliliter of the suspension ranged from 10(1.3) to 10(4.0) (mean 10(2.2)). a total of 47 isolates comprising 26 (55%) facultative anaerobes and 21 (45%) strict anaerobes were obtained. the organisms most commonly cultured were veillonella species (15%), streptococcus milleri (11%), streptococcus sanguis (11%), actinomyces naeslundii (11%), prop ...19902183126
sialidase activity of the "streptococcus milleri group" and other viridans group streptococci.viridans group streptococci were examined for the production of sialidase (neuraminidase) activity, using the fluorescent substrate 4-methylumbelliferyl-alpha-d-n-acetylneuraminic acid in a simple and rapid (15-min) assay. sialidase was produced by all strains of streptococcus oralis and s. intermedius and by a majority of s. mitis strains. s. mutans, s. sobrinus, s. gordonii, s. sanguis, s. vestibularis, s. salivarius, s. anginosus, s. constellatus, "s. parasanguis," and the "tufted fibril grou ...19902199505
group c streptococcal arthritis: case report and review.streptococci account for approximately 15%-20% of cases of nongonococcal septic arthritis. the majority of these are due to group a streptococci, but group b and group g streptococci are being isolated more frequently. we present a case of group c streptococcal arthritis and summarize nine additional cases reported in the literature. the group c streptococci include the large colony of voges-proskauer-negative bacteria (streptococcus equi, streptococcus equisimilis, streptococcus zooepidemicus, ...19902237126
clinical features of patients suffering from streptococcus milleri infections--a retrospective analysis.we examined the clinical records of patients from whom s. milleri was isolated at kyushu university hospital from january 1987 through december 1988. sixty-one patients were treated in 64 episodes with drainage or antibiotics. oral and nasopharyngeal infections were observed in 27 cases, intrathoracic infections in 13, urogenital infections in 8, intraabdominal infections in 6 and skin and subcutaneous infections in 6. except for acute bronchitis and urogenital infections, all of them were suppu ...19921292963
septic streptococcus milleri spondylodiscitis.we describe 2 patients presenting lumbar spondylitis due to streptococcus milleri. in both cases origin was related to preexistent intestinal pathology. surgical drainage of a collection of pus was necessary in one case. longterm antibiotic therapy led to full recovery. despite confused nomenclature streptococcus milleri must be considered a serious pathogen mainly associated with purulent infection with osteoarticular affinity.19902254907
streptococcus milleri (guthof); an indigenous organism of the human oral cavity. 19751061530
cellular coaggregation of oral streptococcus milleri with actinomyces.oral isolates of streptococcus milleri were examined for their ability to coaggregate with actinomyces. of the 68 s. milleri strains tested, including 3 reference strains, 40 strains coaggregated with actinomyces naeslundii wvu45 (actinomyces coaggregation group b) and 36 strains coaggregated with actinomyces viscosus t14v (actinomyces coaggregation group a). all s. milleri strains of serotypes b (4 strains), e (2 strains), and f (24 strains) coaggregated with both of the actinomyces. the coaggr ...19902294047
characteristics of streptococcus milleri and streptococcus mitior from infected dental root canals.morphological and physiological characteristics of 103 streptococcal isolates obtained from positive routine cultures of material from dental root canals at filling, were studied. the majority of the isolates were those which at a primary identification not fullfilled the criteria of enterococci, strep. sanguis, strep. mutans or strep. salivarius. only a few representative strains of the latter types were included in the study as a control of the method. the resemblance of the 103 isolates to 38 ...19751061026
[brain abscess, caused by streptococcus milleri, in an 11 year old girl]. 19761009850
infection with minute-colony-forming beta-haemolytic streptococci.one hundred and thirty-one strains of minute-colony-forming beta-haemolytic streptococci were isolated during the course of routine investigations in clinical bacteriology. each strain was examined for the presence of polysaccharide antigens of lancefield's groups a, c, g, and f and characterized in detail as to biochemical and cultural features. on the results of these tests it is concluded that the strains should be placed in the species streptococcus milleri. the clinical details relevant to ...1976956456
the cultural and biochemical characters of streptococcus milleri strains isolated from human sources.a collection of 346 strains of streptococcus milleri from a variety of human sources was examined culturally and biochemically, and for the presence of lancefield group antigens. most of the strains were non-haemolytic and ungroupable, but 25% were beta haemolytic and 19% were alpha haemolytic; 28% possessed a group antigen (a, 5%; c, 6%, f, 14%, g, 3%). these antigens were present in 69% of beta-haemolytic but in only 13% of alpha-haemolytic or non-haemolytic strains; beta haemolysis occurred i ...1979762404
phenotypic differentiation of streptococcus intermedius, streptococcus constellatus, and streptococcus anginosus strains within the "streptococcus milleri group".a biochemical scheme was developed by which strains of streptococcus constellatus, streptococcus intermedius, and streptococcus anginosus can reliably be distinguished from within the "streptococcus milleri group." strains identified as s. intermedius were differentiated by the ability to produce detectable levels of alpha-glucosidase, beta-galactosidase, beta-d-fucosidase, beta-n-acetylgalactosaminidase, beta-n-acetylglucosaminidase, and sialidase with 4-methylumbelliferyl-linked fluorogenic su ...19902380375
a study of carbon dioxide-dependent strains of streptococcus milleri.forty-four strains of non-haemolytic streptococci, from a variety of sites, that required co2 for aerobic growth were identified as streptococcus milleri. of these strains, 40 (90%) possessed the lancefield group-f antigen, the remainder being non-groupable with antisera to the group antigens a, c, f and g.1978660637
streptococcus milleri in the appendix.the appendix was investigated as a possible habitat of streptococcus milleri. both normal and inflamed appendices were examined and the isolation rates compared. s. milleri was present in a quarter of the normal appendices and more than half of those associated with apendicitis--a difference that was statistically highly significant. the isolation rates throughout were indepencent of age. there was a pronounced connection between the presence of s. milleri in the appendix and the purulent manife ...1977591633
comparative adhesion of seven species of streptococci isolated from the blood of patients with sub-acute bacterial endocarditis to fibrin-platelet clots in vitro.the adhesion to fibrin-platelet clots in vitro of 21 strains of streptococci isolated from the blood of patients with sub-acute bacterial endocarditis (sabe) was measured. the species, in order of greatest adhesion, were streptococcus faecalis, streptococcus mutans, streptococcus milleri, streptococcus sanguis, dextran-positive streptococcus mitior, dextran-negative streptococcus mitior and streptococcus salivarius. individual strains within species, however, cannot be assumed to be representati ...19862422150
surface structures, co-aggregation and adherence phenomena of streptococcus oralis and related species.seven strains of streptococcus oralis were found to possess surface structures. four strains possessed long fimbriae which ranged in length from 266-366 nm, while the remaining three strains possessed shorter peritrichously distributed fibrils which ranged in length from 80-197 nm. the fibrillar strains were morphologically similar to strains of streptococcus sanguis i and ii and streptococcus mitis. no strain of s. oralis produced tufts of fibrils like certain strains of s. sanguis i. strains o ...19892475745
multiple hepatic abscesses caused by streptococcus milleri in association with an intrauterine device.we report a case of streptococcus milleri bacteremia and multiple hepatic abscesses secondary to an intrauterine device and a tuboovarian abscess. hepatic abscess as a complication of an intrauterine device has previously been reported only once, with actinomyces israelii as the causative agent. our patient's hepatic abscesses were cured with medical therapy.19892602778
the relative cariogenicities of streptococcus milleri and other viridans group streptococci in gnotobiotic hooded rats. 1978278551
studies on streptococci resembling streptococcus milleri and on an associated surface-protein antigen.ninety-nine strains of streptococci were isolated from 97 cases of pyogenic infections, most of which involved the teeth. physiological and serological tests were performed on these streptococci and on 37 strains of streptococci from culture collections. the results were used for a numerical classification. seventy-nine of the strains isolated from patients formed a cluster with streptococcus milleri and group-f reference strains, and were therefore considered as streptococci resembling s. mille ...197882618
in-vitro activity of 13 antibiotics against clinical isolates of streptococcus milleri. 19892613609
genetic transformation in some cariogenic streptococcus milleri.only one of six streptococcus milleri strains, known to produce dental caries in gnotobiotic rats, was found to be spontaneously transformable. at optimal competence (after 60 min incubation in transformation medium) dna uptake by this strain, cr 287, was rapid; maximum dna was taken up by cells within 15 min of its addition to give a transformation frequency of 1 x 10(-2) transformants per colony-forming unit (cfu). with post-optimally competent cells, the rate of dna uptake was markedly decrea ...19892615670
[acute osteomyelitis of the femur due to streptococcus milleri]. 19911830149
liver abscess caused by streptococcus milleri.there is now convincing evidence that streptococcus milleri is an important cause of pyogenic liver abscesses. the clinical course is no different from that of pyogenic infections of the liver arising from other causes. a positive blood culture should alert the clinician to the possibility of hepatic suppuration. treatment consists of drainage by laparotomy or percutaneous aspiration combined with approximately 6 weeks of penicillin administration. patients with liver abscesses who receive metro ...19892649957
[spinal cord abscess caused by streptococcus milleri]. 19911825880
immune response in patients with intraabdominal infections treated with imipenem. swedish study group.in the present investigation the humoral immune response against isolated microorganisms in patients treated with imipenem was studied. sixty-six patients (34 men and 32 women, 18-86 years of age) with suspicion of intraabdominal infections entered the study. five patients were excluded for various reasons and the remaining 61 patients were treated with imipenem/cilastatin 0.5-1.0 g t.i.d. for 5-29 days (median nine days). three serum samples were taken from each patient, the first sample at adm ...19892693357
identification of viridans streptococci by pyrolysis-gas chromatography.an isothermal method of pyrolysis-gas chromatography (py-gc) was used for the identification of viridans streptococci. pyrograms from 104 reference strains were subjected to a discriminant analysis to produce classification coefficients for the identification of 74 test organisms. five groups representing recognised species were discriminated but streptococcus milleri strains could not be distinguished from s. sanguis. if s. milleri and s. sanguis are regarded as a single pyrogroup, only three s ...19892724324
hyaluronidase production in streptococcus milleri in relation to infection.one hundred and seven (41%) of 262 isolates of streptococcus milleri, from human sources, produced hyaluronidase. hyaluronidase production was commoner in beta haemolytic isolates 32 of 39 (82%), many of which were of lancefield group f. but hyaluronidase was also found in alpha and non-haemolytic isolates, and in groups a, c, g, and non-groupable isolates. there was a strong association between hyaluronidase production and isolation from known internal abscesses (48/58, 83%) compared with isola ...19892732345
carbohydrate antigen of serotype g "streptococcus milleri": immunochemical characterization.cell wall carbohydrate antigen of the serotype g "streptococcus milleri" was extracted with cold trichloroacetic acid from purified cell walls of the type strain k1k. the extracts were then purified by a deae-sephadex a-25 column, followed by a sephadex g-100 column. the immunoelectrophoresis revealed that the serotype g carbohydrate antigen preparation displayed a single precipitin band against the crude anti-k1k serum. the purified type g antigen consisted of rhamnose, galactose, glucose and g ...19911820568
[bacteriology of abdominal pus in 43 cases of acute appendicitis and appendiceal abscess at the ivrea-castellamonte hospital, isolation of aerobic and anaerobic bacteria and drug sensitivity].a retrospective study on the microbiology of abdominal pus from acute appendicitis or peritonitis was carried out by the authors. a total of 45 specimens were examined, 38 of them (84.4%) where found to be positive, of which 29 (76.3%) were polymicrobial and 9 (23.7%) were monomicrobial. the most represented species were escherichia coli (28.4%), bacteroides fragilis (7.8%), streptococcus milleri (7.8%), bacteroides oralis (3.9%) and pseudomonas aeruginosa (3.9%). the polymicrobial associations ...19911844922
infective sacroiliac arthritis and psoas abscess caused by streptococcus milleri. 19892778345
gardnerella vaginalis bacteremia from pulmonary abscess in a male alcohol abuser.a case of gardnerella vaginalis bacteremia is reported. this bacteremia occurred in a male alcohol abuser who developed definite signs of pulmonary abscess and empyema. streptococcus milleri grew from another blood culture, but gardnerella vaginalis was also isolated from a bronchoscopic aspirate and pleural drainage sample as part of mixed flora containing anaerobes, streptococcus species, neisseria sicca, and a haemophilus sp. we discuss the possible pathogenic character of g. vaginalis outsid ...19892787333
additional case of liver abscess due to streptococcus milleri. 19892814167
[the relationship between predisposing factors in liver abscesses and the causative bacteria].in order to assess the correlation between bacteria isolated from liver abscesses and factors predisposing to liver abscesses, a retrospective study of clinical and bacteriological data on 21 patients with 27 episodes of pyogenic abscesses was carried out at the university medical centre, amsterdam. out of 27 episodes, 15 (55%) were associated with biliary or pancreatic disease; in seven of these 15 episodes more than one microorganism was cultured. enterobacteriaceae were isolated in 13 (85%) o ...19911922453
adherence of oral "streptococcus milleri" cells to surfaces in broth cultures.cells of representative strains of oral "streptococcus milleri" firmly adhered to glass surfaces when grown in glucose broths as well as in fructose and sucrose broths. cellular adherence occurred on saliva-coated glass surfaces as well as uncoated surfaces, but the cells of only a few (6 of 69) tested adherent strains agglutinated upon the addition of human whole-saliva supernatant. thus, the firm adherence of growing "s. milleri" cells is independent of sucrose and salivary macromolecules. two ...19911937769
cefotaxime lavage in children undergoing appendicectomy.in an attempt to reduce postoperative sepsis, a series of randomised, double-blind studies was begun in 1982, using cefotaxime as backbone therapy. up to 1985 (stages i and ii), the best results were obtained using a combination of cefotaxime (75 mg/kg intravenously in 3 doses at 12-hourly intervals) plus metronidazole (10 mg/kg intravenously in 3 doses), both drugs administered 1 hour before surgery (preoperatively) or at anaesthetic induction (peroperatively). in 300 consecutive cases, the wou ...19882899496
enumeration of oral streptococci on media containing different concentrations of sodium and potassium ions.laboratory "type" strains of oral streptococci were screened for their ability to grow on mitis-salivarius agar (msa) in the presence of increasing concentrations of either na+ or k+ up to 500 mmol/l. strains were generally better able to withstand increasing concentrations of na+ than k+, although low numbers of colony-forming units (cfus) were seen with the highest concentration of either cation. two strains of streptococcus mutans, ingbritt 162 and ingbritt 175, behaved differently when the c ...19911939833
open study of teicoplanin in gram-positive infections.eighteen patients with documented gram-positive infections which included osteomyelitis, prosthetic infections, endocarditis, skin and soft tissue, and urinary tract infections were treated with teicoplanin. the organisms involved included staphylococcus aureus (15 isolates of which six were methicillin-resistant-mrsa), staphylococcus epidermidis (two), streptococcus faecalis (one) and streptococcus milleri (one). clinical success occurred in all seven patients with skin and soft tissue streptoc ...19882967801
beta-d-glucuronidase activity assay for rapid differentiation of species within beta-haemolytic group c and g streptococci.methylumbelliferyl-conjugated enzyme substrates were assessed for their ability to differentiate beta haemolytic streptococci in lancefield groups c and g. both streptococcus equisimilis (group c) and large colony human biotype group g strains were consistently differentiated from group c and g "streptococcus milleri group" bacteria by their ability to hydrolyse the beta-d-glucuronide substrate. the test was completed in less than one hour.19911960215
emended descriptions and recognition of streptococcus constellatus, streptococcus intermedius, and streptococcus anginosus as distinct species.strains currently classified as streptococcus anginosus include strains previously identified as streptococcus constellatus (prevot 1924) holdeman and moore 1974, streptococcus intermedius (prevot 1925), and "streptococcus milleri" (guthof 1956) because these specific epithets were argued to be later synonyms of streptococcus anginosus (andrewes and horder 1906) smith and sherman 1938 by coykendall et al. (int. j. syst. bacteriol. 37:222-228, 1987). however, recent data from dna-dna hybridizatio ...19911995029
streptococcus milleri group (streptococcus anginosus): recovery from intra-abdominal and soft tissue sites.one hundred thirty-three streptococcus milleri group (s. anginosus) isolates were recovered from 487 surgical patients. the streptococci were recovered from 33 percent of intra-abdominal infection cultures (84/257). 22 percent of samples from penetrating visceral trauma (19/86), 52 percent of perirectal abscess specimens (13/25), 13 percent of nonpuerperal breast abscess cultures (8/60), and 15 percent of diabetic foot lesions (9/59). ninety-eight percent of the s. milleri (131/133) were recover ...19912012380
streptococcus anginosus ("streptococcus milleri"): the unrecognized pathogen."streptococcus milleri" is an unofficial name that has been applied to a group of streptococci which, although basically similar, show various hemolytic, serological, and physiological characteristics. the species name streptococcus anginosus has recently been recognized as the approved name for these organisms. streptococci known as "s. milleri" have been implicated as etiologic agents in a variety of serious purulent infections, but because of their heterogeneous characteristics, these organis ...19883060239
a case of effusive constrictive pericarditis caused by streptococcus milleri.a 55-year-old male presented with hypotension and marked elevation of jugular venous pressure suggesting impaired ventricular filling. echocardiography demonstrated a moderate amount of pericardial effusion and dense and shaggy fibrinous strands attached to the pericardia. pericardiocentesis was performed under the diagnosis of cardiac tamponade, but normal ventricular filling could not be restored even after pericardiocentesis. hemodynamic evaluation after pericardiocentesis revealed persisting ...19912020085
subperiosteal abscesses of the orbit due to sinusitis in childhood.this paper reports 16 cases of subperiosteal abscesses of the orbit due to acute sinusitis in childhood. they comprise 12.4% of 129 patients presenting with an 'acute orbit'. acute ethmoidal sinusitis was the predominant cause. the typical clinical features, as well as ct scanning of the paranasal sinuses, orbit and brain, should assist in early diagnosis. if possible, the subperiosteal abscess and sinuses should be drained before loss of visual acuity or intracranial complications occur. strept ...19912039621
[gangrenous and perforating appendicitis in a provincial hospital: a 48-month retrospective study. clinical and microbiological aspects, course and postoperative morbidity].the appendectomy for gangrenous or perforated appendicitis is made more serious by a very high frequency of infection. the antibiotic prophylaxis should be able to reduce the frequency of such complications. we have considered retrospectively the patients who underwent appendectomy for gangrenous and perforated appendicitis in the period from june 1st, 1986 to may 31st 1990 in the ivrea-castellamonte hospital (province of turin), focusing our attention on certain microbiological and clinical var ...19902133325
[studies on suppurative lesion and bone distribution of peroral antimicrobial agents (lapc and tflx) to experimental infected rabbits].the models of infection in the rabbits mandible using streptococcus milleri and bacteroides fragilis by the method of satoh-heimdahl were prepared. a penicillic peroral antimicrobial agent, lenamipicillin (lapc), and pyridone carboxylic acid peroral antimicrobial agent, tosufloxacin tosilate (tflx), were administered to infected and healthy groups. drug concentrations in the serum, pus, mandible, maxilla, humerus, sternum, costa, ilium, femur, tibia, liver, and kidney were determined by a biolog ...19902134803
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