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a human adenovirus species b subtype 21a associated with severe pneumonia.between 2005 and 2013 six severe pneumonia cases (all requiring mechanical ventilation, two fatal outcomes) caused by human adenovirus type 21 (hadv-b21) were observed in germany. so far, hadv-b21 was mainly associated with non-severe upper and lower respiratory tract infections. however, a few highly virulent hadv types, e.g. hadv-b14p1, were previously associated with severe, fatal pneumonia. complete genomic sequences of the german hadv-b21 pneumonia isolates formed a single phylogenetic clus ...201424975176
molecular epidemiology of adenovirus type 21 respiratory strains isolated from us military trainees (1996-2014).the circulation of human adenovirus type 21 (hadv21) in the united states has been documented since the 1960s in association with outbreaks of febrile respiratory illness (fri) in military boot camps and civilian cases of respiratory disease.201525748322
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