| constituents of eriobotrya japonica. a study of their antiviral properties. | the chcl3 extract of eriobotrya japonica from an italian source was shown to contain four new triterpene esters, namely, 23-trans-p-coumaroyltormentic acid [1], 23-cis-p-coumaroyltormentic acid [2], 3-o-trans-caffeoyltormentic acid [3], and 3-o-trans-p-coumaroylrotundic acid [4], in addition to three common ursolic acid derivatives 5, 6, and 7. an investigation of the antiviral properties of compounds 1-7 revealed that only 3 significantly reduced rhinovirus infection. the compounds were ineffec ... | 1992 | 1279126 |
| hypoglycemic effects of sesquiterpene glycosides and polyhydroxylated triterpenoids of eriobotrya japonica. | the effects of the constituent sesquiterpene glycosides 1-3 and polyhydroxylated triterpenoids 5-6 isolated by meoh extraction of eriobotrya japonica were studied in genetically diabetic mice (c57bl/ks-db/db/ola) and normoglycemic rats. the sesquiterpene glycoside 3 and the polyhydroxylated triterpenoids 5 and 6 produced a marked inhibition of glycosuria. furthermore, 5 and 6 were able to reduce blood glucose levels in normoglycemic rats. while there are already some data reported on hypoglycemi ... | 1991 | 1798792 |
| experimental study of the hypoglycemic effect of some antidiabetic plants. | the purpose of this work is to look for the hypoglycemic effect of 12 plants most used in mexico for controlling diabetes mellitus. the studies were realized in 27 rabbits submitted weekly to glucose tolerance tests after gastric administration of water, tolbutamide or a preparation of the plant. the results showed that tolbutamide and studied plants (except aloe barbadensis) decreased significantly (p less than 0.05) the area under glucose tolerance curve, in relation with the water control. th ... | 1991 | 1819981 |
| [loquat canker: a new disease for argentina]. | a stem canker disease caused by pseudomonas syringae pv. eriobotryae (takimoto) young, dye y wilkie on loquat (eriobotrya japonica [thumb] lindl) was recorded for the first time in argentina. symptoms of the disease appeared as dry stem cankers which in advanced stages surrounded the stems. similar cankers were noticeable on leaves midribs. seven bacterial strains were isolated from diseased loquats and their identification was based on disease symptoms, pathogenicity and cultural and biochemica ... | 1990 | 2102015 |
| effect of eriobotrya japonica on blood glucose levels of normal and alloxan diabetic rabbits. | | 1988 | 3138460 |
| effect of eriobotrya japonica on blood glucose levels of normal and alloxan-diabetic rabbits. | | 1988 | 3174854 |
| anti-inflammatory constituents of topically applied crude drugs. i. constituents and anti-inflammatory effect of eriobotrya japonica lindl. | | 1986 | 3769076 |
| ursolic acid inhibits aflatoxin b1-induced mutagenicity in a salmonella assay system. | an attempt was made to isolate the active component of eriobotrya japonica, which inhibits aflatoxin b1-induced mutagenicity in the salmonella assay system. the number of revertants per plate was significantly decreased when a meoh extract of eriobotrya japonica was added to the assay system using salmonella typhimurium ta100 or ta98. furthermore, we examined the effect of each fraction purified from the meoh extract, and an etoac fraction was found to be the most effective. ursolic acid isolate ... | 1994 | 8000393 |
| antioxidant flavonoids and chlorogenic acid from the leaves of eriobotrya japonica. | the antioxidant activity of eriobotrya japonica was determined by measuring the radical scavenging effect on dpph (1,1-diphenyl-2-picrylhydrazyl) radical and lipid peroxidation produced when mouse liver homogenate was exposed to the air at 37 degrees c, using 2-thiobarbituric acid (tba). the methanol extract and its fractions of eriobotrya japonica leaves showed strong antioxidant activity. the antioxidant activity of etoac and n-buoh soluble fractions were stronger than the others, and were fur ... | 1999 | 10230515 |
| immunological and molecular comparison of polyphenol oxidase in rosaceae fruit trees. | an antibody raised against apple polyphenol oxidase (ppo) cross-reacted with ppos from japanese pear (pyrus pyrifolia), pear (pyrus communis), peach (prunus persica), chinese quince (pseudocydonia sinensis) and japanese loquat (eriobotrya japonica). core fragments (681 bp) of the corresponding ppo genes were amplified and characterized. the deduced protein sequences showed identities of 85.3 to 97.5%. chlorogenic acid oxidase activity of these ppos showed higher activities when assayed at ph 4 t ... | 1999 | 10385997 |
| polyphenols from eriobotrya japonica and their cytotoxicity against human oral tumor cell lines. | three new flavonoid glycosides, together with 15 known flavonoids, have been isolated from the leaves of eriobotrya japonica, and characterized as (2s)- and (2r)-naringenin 8-c-alpha-l-rhamnopyranosyl-(1-->2)-beta-d-glucopyranosides, and cinchonain id 7-o-beta-d-glucopyranoside, respectively, based on spectral analyses including two dimensional (2d) nmr techniques. higher proanthocyanidin fraction in the water-soluble portion of the extract was characterized as a procyanidin oligomer mixture mai ... | 2000 | 10823708 |
| inhibition of nfkappab by methyl chlorogenate from eriobotrya japonica. | methylchlorogenic acid (mc) is one of the main components in the leaves of eriobotrya japonica. we previously reported that mc is the most potent antioxidant among several components of eriobotrya japonica, and its antioxidant activity is stronger than that of chlorogenic acid. antioxidants are expected to inhibit redox-sensitive nfkappab activation since nfkappab is readily influenced by cellular oxidative state. based on these findings, in vivo experiments with mc were conducted to determine i ... | 2000 | 10901160 |
| physiological and antagonistic potential of actinomycetes from loquat rhizosphere. | the microflora of eriobotrya japonica (loquat) was studied by the serial dilutions-spread plate method. a variety of bacteria, fungi and actinomycetes was detected. the genus steptomyces dominated in the population (83%). a great species diversity was found among streptomycetes. some of the actinomycetes possessed antibacterial activity (47%), others produced different exo-enzymes. | 2000 | 10950197 |
| production of bioactive triterpenes by eriobotrya japonica calli. | callus tissue cultures induced from an axenic leaf of eriobotrya japonica (rosaceae) produced triterpenes in large amounts (ca. 50 mg/g dry wt). nine triterpenes were characterized as ursolic acid, oleanolic acid, 2alpha-hydoxyursolic acid, maslinic acid, tormentic acid, 2alpha, 19alpha-dihydroxy-3-oxo-urs-12-en-28-oic acid, hyptadienic acid and a mixture of 3-o-cis-p-coumaroyltormentic acid and 3-o-trans-p-coumaroyltormentic acid. the triterpene composition in the callus tissues was noticeably ... | 2002 | 11830140 |
| antitumor activity of compounds isolated from leaves of eriobotrya japonica. | in a search for possible antitumor agents from natural sources, megastigmane glycosides and polyphenolic constituents isolated from the leaves of eriobotrya japonica (rosaceae) were found to inhibit the 12-o-tetradecanoylphorbol-13-acetate (tpa)-induced activation of epstein-barr virus early antigen in raji cells. roseoside and procyanidin b-2 were among the active compounds found in an in vitro assay; these compounds were further assessed for antitumor activity in vivo in a two-stage carcinogen ... | 2002 | 11929303 |
| carotenol fatty acid esters: easy substrates for digestive enzymes? | to study the specificity of gastric lipases on carotenoid mono- and diesters, an enzymatic assay was applied. digestions were carried out in phosphate buffer at ph 7.4 and 37 degrees c. as substrates we employed oleoresins from marigold (tagetes erecta l.; lutein diesters), red paprika (capsicum annuum l., mainly capsanthin diesters), papaya (carica papaya l.; beta-cryptoxanthin esters), and loquat (eriobotrya japonica lindl.; beta-cryptoxanthin esters) as well as retinyl palmitate. these were r ... | 2002 | 12128058 |
| effects of extract derived from eriobotrya japonica on liver function improvement in rats. | eriobotrya japonica is considered a medicinal plant, and its leaves (eriobotrya folia) have been used to treat skin diseases, as well as to relieve inflammation, pain, coughing, and sputa. in our evaluation of the pharmacological efficacy of the seed extracts, constituents of the seeds were found to contain the unsaturated fatty acids linolenic and linoleic acids and the sterol beta-sitosterol in the 70% etoh and the meoh extracts. the seed extracts were orally administered to rats with dimethyl ... | 2002 | 12186409 |
| native and introduced host plants of anastrepha fraterculus and ceratitis capitata (diptera: tephritidae) in northwestern argentina. | wild or commercially grown, native and exotic fruit were collected in 30 localities in the tucumán province (nw argentina) from january 1990 to december 1995 to determine their status as hosts of anastrepha fraterculus (wiedemann) and/or ceratitis capitata (wiedemann), the only two fruit fly species of economic and quarantine importance in argentina. a total of 84,094 fruit (3,466.1 kg) representing 33 species (7 native and 26 exotic) in 15 plant families were sampled. we determined the followin ... | 2003 | 14503581 |
| tissue factor inhibitory sesquiterpene glycoside from eriobotrya japonica. | tissue factor (tf, tissue thromboplastin) is a membrane bound glycoprotein, which accelerates the blood clotting, activating both the intrinsic and the extrinsic pathways to serve as a cofactor for activated factor vii (viia). the tf-factor viia complex (tf/viia) proteolytically activates factors ix and x, which leads to the generation of thrombin and fibrin clots. in order to isolate tf inhibitors, by means of a bioassay-directed chromatographic separation technique, from the leaves of eriobotr ... | 2004 | 15283463 |
| the effect of eriobotrya japonica seed extract on oxidative stress in adriamycin-induced nephropathy in rats. | eriobotrya japonica has been used as a medicinal plant for a long time, and its leaves are known to have many physiological actions such as anti-inflammatory, antitussive, and expectoran. in contrast, eriobotrya japonica seeds are only known to contain amygdalin, and almost no investigations of its pharmacological action have been performed. moreover, some anticancer agents such as adriamycin cause renal disorders as an adverse effect, and the mechanism of the adverse effect is considered to inv ... | 2004 | 15577213 |
| anti-inflammatory and antitumor-promoting effects of the triterpene acids from the leaves of eriobotrya japonica. | sixteen triterpene acids, viz., five of the oleanane-type (1-5), nine of the ursane-type (6-14), and two of the lupane-type (15, 16), were isolated and identified from the ethyl acetate-soluble fraction of the methanol extract of the leaves of loquat, eriobotrya japonica lindl. (rosaceae). twelve of these compounds, 1-4, 6, 8-13, and 15, were evaluated for their inhibitory effects on 12-o-tetradecanoylphorbol-13-acetate (tpa)-induced inflammation (1 microg/ear) in mice. all the compounds tested ... | 2005 | 16204964 |
| anti-oxidative effect of triterpene acids of eriobotrya japonica (thunb.) lindl. leaf in chronic bronchitis rats. | the study was to evaluate the effect of triterpene acids of eriobotrya japonica (thunb.) lindl. leaf (tal) on expression of antioxidative mediators by alveolar macrophages (am) in rats with chronic bronchitis (cb), cb was induced by endotracheal instillation of lipopolysaccharedes (lps) followed by bacillus calmette-guérin (bcg) injection through caudal vein 1 week later. treatment groups received tal at there different doses (50, 150, or 450 mg/kg daily, intragastrically (i.g.)) or dexamethason ... | 2006 | 16352318 |
| scavenging of reactive oxygen species by eriobotrya japonica seed extract. | we have clarified that eriobotrya japonica seed extract has strong antioxidative activity, and is effective for the prevention and treatment of various diseases, such as hepatopathy and nephropathy. in this study, to investigate the influences of components of eriobotrya japonica seed extract on its antioxidative activity, extracts were prepared using various solvents (n-hexane (hex), ethyl acetate (etoac), n-butanol (n-buoh), methanol (meoh) and h2o) and the antioxidative activity of the solven ... | 2006 | 16508147 |
| screening of traditional antidiabetic medicinal plants of mauritius for possible alpha-amylase inhibitory effects in vitro. | in this study, seven exotic/indigenous medicinal plants of mauritius, namely coix lacryma-jobi (poaceae), aegle marmelos (rutaceae), artocarpus heterophyllus (moraceae), vangueria madagascariensis (rubiaceae), azadirachta indica (meliaceae), eriobotrya japonica (rosaceae) and syzigium cumini (myrtaceae) were studied for possible effects on starch breakdown by alpha-amylase in vitro. the results showed that only artocarpus heterophyllus significantly (p < 0.05) inhibited alpha-amylase activity in ... | 2006 | 16521114 |
| purification and characteristics of sorbitol-6-phosphate dehydrogenase from loquat leaves. | to study the role of sorbitol-6-phosphate dehydrogenase in sorbitol synthesis in leaves of rosaceous plants, properties of the enzyme and its presence in several plants in the family was investigated. the activity of the enzyme, which catalyzes an nadp-dependent oxidation of the substrate to glucose-6-phosphate, was detected in leaves of prunus mume, prunus persica, rhaphiolepsis indica, sorbus aucuparia, cydonia oblonga, photinia glabra, sorbaria kirilowii, and spiraea thunbergii.the enzyme was ... | 1981 | 16661650 |
| evaluation of oriental medicinal herbs for estrogenic and antiproliferative activities. | herb extracts commercially used in asia were screened for their estrogenic activity with a recombinant yeast system with both a human estrogen receptor (er) expression plasmid and a reporter plasmid. pueraria lobata (flower) had the highest estrogenic relative potency (rp, 17-estradiol = 1.00) (7.8e-3) (rp for + control), followed by amomum xanthioides (1.3e-3), glycyrrhiza uralensis, zingiber officinale, rheum palmatum, curcuma aromatica, eriobotrya japonica, sophora flavescens, anemarrhena asp ... | 2006 | 16906642 |
| hypoglycemic effects of a sesquiterpene glycoside isolated from leaves of loquat (eriobotrya japonica (thunb.) lindl.). | sesquiterpene glycoside, nerolidol-3-o-alpha-l-rhamnopyranosyl(1-->4)-alpha-l-rhamnopyranosyl(1-->2)-[alpha-l-rhamnopyranosyl(1-->6)]-beta-d-glucopyranoside was isolated from dried leaves of loquat [eriobotrya japonica (thunb.) lindl., rosaceae]. hypoglycemic effects of this natural product were assessed in normal and alloxan-diabetic mice model. animals received orally administration of the sesquiterpene glycoside in dose of 25 and 75 mg/kg. the anti-hyperglycemic effect was compared with glicl ... | 2008 | 17291739 |
| effect of triterpene acids of eriobotrya japonica (thunb.) lindl. leaf on inflammatory cytokine and mediator induction from alveolar macrophages of chronic bronchitic rats. | the study was to evaluate the effect of triterpene acids of eriobotrya japonica (thunb.) lindl. leaf (tal) on inflammatory cytokine and mediator expression in alveolar macrophages (am) of chronic bronchitic (cb) rats. | 2007 | 17431744 |
| pharmacological studies on anti-hyperglycemic effect of folium eriobotryae. | folium eriobotryae, dried leaves of eriobotrya japonica (thunb.) lindl. is a traditional chinese medicine with rich resources in china. this research investigated the anti-hyperglycemic effect of folium eriobotryae on normal and alloxan-diabetic mice. the 70% ethanol extract of folium eriobotryae (eja-0) in doses of 15, 30 and 60 g (crude drug)/kg exerted a significant hypoglycemic effect on alloxan-diabetic mice, among which 30 g/kg of eja-0 was more effective than 100 mg/kg of phenformin. the ... | 2007 | 17708636 |
| effect of orally administered eriobotrya japonica seed extract on allergic contact dermatitis in rats. | the anti-allergic activity of eriobotrya japonica seeds extract (ese) was investigated. oral administration of ese dramatically inhibited ear swelling due to allergic contact dermatitis caused by repeated application of two antigens, 4-ethoxymethylene-2-phenyl-2-oxazolin-5-one (oxazolone) and dinitrofluorobenzene (dnfb), respectively. the increase of histamine content in inflamed ear tissue induced by oxazolone and dnfb was significantly antagonized by orally administered ese. eosinophil peroxid ... | 2007 | 17910816 |
| the differential effect of eriobotrya japonica hydrophilic leaf extract on cytokines production and modulation. | stimulating or modulating the release of cytokines by immunomodulators or immunostimulating agents is an attractive mode for treating several diseases such as viral infections. for instance, patients with viral infections may be in need of increasing or inducing t helper 1 (th1) or proinflammatory cytokines, which ultimately activate t cytotoxic and natural killer lymphocytes to kill virally infected cells. of these agents, we found that eriobotrya japonica hydrophilic leaf extract (ejhe) can in ... | 2007 | 18036829 |
| hypoglycemic activity of eriobotrya japonica seeds in type 2 diabetic rats and mice. | the hypoglycemic effects of eriobotrya japonica seeds were investigated in type 2 diabetic otsuka long-evans tokushima fatty (oletf) rats and kk-a(y) mice. the rats and mice were fed on a diet containing 10% powdered eriobotrya japonica seeds with the coat intact for 4 months. although the blood glucose concentration in the oletf rats fed on the control diet without eriobotrya japonica seeds was increased with time, the concentration in the oletf rats fed on the diet with eriobotrya japonica see ... | 2008 | 18323632 |
| gastroprotective activity of eriobotrya japonica seed extract on experimentally induced gastric lesions in rats. | the effect of eriobotrya japonica seed extract (ese) prepared with 70% ethanol on gastric mucosal injury was investigated. six experimental models with different action mechanisms were used for the evaluation. three concentrations of ese were prepared for each model. ese administration was initiated 14 days before induction of gastric mucosal injury, and its effect was investigated. ese inhibited formation of gastric mucosal injury. | 2008 | 18404352 |
| purification and characterization of a novel (r)-hydroxynitrile lyase from eriobotrya japonica (loquat). | a hydroxynitrile lyase was isolated and purified to homogeneity from seeds of eriobotrya japonica (loquat). the final yield, of 36% with 49-fold purification, was obtained by 30-80% (nh(4))(2)so(4) fractionation and column chromatography on deae-toyopearl and concanavalin a sepharose 4b, which suggested the presence of a carbohydrate side chain. the purified enzyme was a monomer with a molecular mass of 72 kda as determined by gel filtration, and 62.3 kda as determined by sds-gel electrophoresis ... | 2008 | 18540101 |
| improved control of anthracnose rot in loquat fruit by a combination treatment of pichia membranifaciens with cacl(2). | the beneficial effect of 2% cacl(2) (w/v) on the antagonistic yeast pichia membranifaciens for control of anthracnose rot caused by colletotrichum acutatum in postharvest loquat fruit (eriobotrya japonica l.) and the possible mechanisms involved were investigated. the results showed that treatment with p. membranifaciens at 1x10(8) cfu ml(-1) or 2% cacl(2) alone both resulted in significantly smaller lesion diameter and lower disease incidence of anthracnose rot on loquat fruit wounds compared w ... | 2008 | 18590937 |
| eriobotrya japonica leaf and its triterpenes inhibited lipopolysaccharide-induced cytokines and inducible enzyme production via the nuclear factor-kappab signaling pathway in lung epithelial cells. | pulmonary inflammation is a characteristic of many lung diseases. increased levels of inducible nitric oxide synthase (inos), cyclooxygenase-2 (cox-2), and proinflammatory cytokines, such as interleukin-1beta (il-1beta), tumor necrosis factor-alpha (tnf-alpha) and il-8, have been correlated with lung inflammation. in this study, we used lipopolysaccharide (lps) to induce inos, cox-2, and cytokines (tnf-alpha, il-1beta, and il-8) productions in human lung epithelial cells (a-549). leaf of eriobot ... | 2008 | 19051345 |
| in vitro fasciolicide activity of some plant extracts against newly excysted flukes. | the aim of the present study was to evaluate, under in vitro conditions, the activity of 20 plant extracts against newly excysted fasciola hepatica metacercariae. the plants were selected on the basis of anthelmintic activity, traditional use, availability, solubility, and permanence in the liver. for the in vitro evaluation, 24-well nunc-immunoplates containing rpmi-1640 culture medium bovine sera plus antibiotics were used. extract concentrations of 500 and 50 mg/ml were placed in triplicate. ... | 2008 | 19120205 |
| animal studies supporting the inhibition of mast cell activation by eriobotrya japonica seed extract. | the potent antioxidant activity of eriobotrya japonica seed extract (ese) and its usefulness in the prevention and treatment of various disorders has been reported previously. its antioxidant activity associated with beta-sitosterol and polyphenols contained in the extract was also validated. in this study, anti-allergic activity of eriobotrya japonica seed extract was investigated. | 2009 | 19178772 |
| cinchonain ib isolated from eriobotrya japonica induces insulin secretion in vitro and in vivo. | eriobotrya japonica leaves had been used traditionally for the treatment of diabetes mellitus by immersing the dried leaves in a hot water drink. few studies have shown the hypoglycemic effect of eriobotrya japonica using crude alcoholic extract and isolated methanolic compounds. these studies proposed that the mechanism of action could be by stimulating the beta-islets of langerhans to secrete insulin, however with no scientific evidence. | 2009 | 19397981 |
| hypoglycemic effect of the total flavonoid fraction from folium eriobotryae. | the antidiabetic effect of the total flavonoids fraction from leaves of eriobotrya japonica (ejf) was evaluated through normal and streptozotocin-induced diabetic mice with graded oral doses of 150, 300, 450 mg/kg for 7 days or 14 days. the result showed that the dose of 300 mg/kg and 450 mg/kg resulted significant hypoglycemic effect on normal mice, the dose of 300 mg/kg induced significant decrease in plasma glucose concentration (pgc), glycosylated serum protein (gsp), total cholesterol (tc) ... | 2009 | 19427773 |
| hypoglycemic and hypolipidemic effects of the total triterpene acid fraction from folium eriobotryae. | for seeking the good natural material to develop new agent to treat diabetes, the total triterpene acid (tta) fraction extracted from folium eriobotryae [leaves of eriobotrya japonica (thunb.) lindl.] was evaluated for its hypoglycemic and hypolipidemic potential through normal, alloxan and streptozotocin-induced diabetic mice administered with graded oral doses (100, 200, 300 mg/(kg day)) for 7 or 14 days. the results showed that a dose of 300 mg/kg of tta is the most effective dose to cause si ... | 2009 | 19429317 |
| anti-inflammatory effect of triterpenoic acids of eriobotrya japonica (thunb.) lindl. leaf on rat model of chronic bronchitis. | this study was designed to investigate the anti-inflammatory effect of triterpenoic acids from eriobotrya japonica (thunb.) lindl. (tal) on chronic bronchitis (cb) in rats. cb model was established by combination of bacillus calmette-guerin (bcg, 5 mg/kg, injected through the caudal vein) and lipopolysaccharide (lps, 1 g/l, injected through endotracheal intubation). rats with cb model were treated with tal (50, 150 and 450 mg/kg) for 3 weeks. the leukocytes in bronchoalveolar lavage fluid (balf) ... | 2009 | 19507274 |
| effect of leaves of eriobotrya japonica on anaphylactic allergic reaction and production of tumor necrosis factor-alpha. | leaves of eriobotrya japonica lindl. (rosaceae) (lejl) have been used as traditional medicines for inflammatory diseases and chronic bronchitis. however, its effect on mast cell-mediated anaphylactic reaction is not known. the anaphylactic allergic reaction is involved in many allergic diseases such as asthma and allergic rhinitis. in this report, we investigate the effect of lejl on the anaphylactic allergic reaction and studied its possible mechanisms of action. lejl inhibited compound 48/80-i ... | 2009 | 19514997 |
| anti-inflammatory effect of leaves of eriobotrya japonica correlating with attenuation of p38 mapk, erk, and nf-kappab activation in mast cells. | mast cell-mediated allergic inflammation is involved in many diseases such as asthma and sinusitis. mast cells induce synthesis and production of pro-inflammatory cytokines including tumor necrosis factor (tnf)-alpha, interleukin (il)-6, and il-8 with immune regulatory properties. in the present study, we investigate the effect an unspecified aqueous extract from leaves of eriobotrya japonica lindl. (rosaceae) (lejl) on the expression of pro-inflammatory cytokines and its possible mechanisms of ... | 2009 | 19665545 |
| flame atomic absorption spectrometric determination of pb, cd, and cu in pinus nigra l. and eriobotrya japonica leaves used as biomonitors in environmental pollution. | the assessment of trace metal pollution in gaziantep city-turkey has been studied using plant leaves of pinus nigra l. and eriobotrya japonica as biomonitor. the concentrations up to 3,056 mg pb kg(-1) in the needles of pinus nigra l., and 367 ng cd g(-1) in the leaves of eriobotrya japonica were determined. the observed cu concentrations were in range of 1.6-7.1 mg kg(-1). the pb, cd, and cu levels in soils were determined to be in the range of 17-602, 0.142-0.656, and 12-38 mg kg(-1), respecti ... | 2010 | 19784536 |
| effect of triterpene acids of eriobotrya japonica (thunb.) lindl. leaf and mapk signal transduction pathway on inducible nitric oxide synthase expression in alveolar macrophage of chronic bronchitis rats. | the goal of this study was to investigate the possible therapy mechanism of triterpene acids of eriobotrya japonica (thunb.) lindl. leaf (tal) in alveolar macrophage (am) of chronic bronchitis (cb) rats. cb model was established by injection of bacillus calmette guein (bcg) plus lipopolisacharide (lps) in rats. tal significantly inhibited the increased no concentration, inos expression and phosphorylation of p38 mapk in alveolar macrophages (ams) of cb rats. using in vivo test, we found that sb2 ... | 2009 | 19938219 |
| loquat (eriobotrya japonica) extracts suppress the adhesion, migration and invasion of human breast cancer cell line. | we examined the inhibitory effects of loquat methanol extract on the adhesion, migration, invasion and matrix metalloproteinase (mmp) activities of mda-mb-231 human breast cancer cell line. cells were cultured with dmso or with 10, 25, or 50 microg/ml of loquat methanol extract. both leaf and seed extracts significantly inhibited growth of mda-mb-231 cells in a dose-dependent manner, although leaf extract was more effective. adhesion and migration were significantly inhibited by loquat extracts ... | 2009 | 20098577 |
| ecology and behavior of pezothrips kellyanus (thysanoptera: thripidae) on citrus. | the most common thrips species found in cyprus citrus orchards between 2003 and 2008 were pezothrips kellyanus (bagnall) (thysanoptera: thripidae), frankliniella occidentalis (pergande) (thysanoptera: thripidae), and thrips tabaci (lindeman) (thysanoptera: thripidae). only pezothrips kellyanus, kelly's citrus thrips (kct) causes feeding damage on citrus fruits in cyprus. kct adults prefer to concentrate mostly in the northern and eastern sides of both lemon and grapefruit canopies. the attractiv ... | 2010 | 20214367 |
| suppression of blood glucose level by a new fermented tea obtained by tea-rolling processing of loquat (eriobotrya japonica) and green tea leaves in disaccharide-loaded sprague-dawley rats. | in the field of food science, much interest has been focused on the development of alternative medicinal foods with the ability to regulate excess blood glucose level (bgl) rise. the authors have successfully developed a new fermented tea product (lg tea) by co-fermentation of loquat (eriobotrya japonica) leaf and summer-harvested green tea leaf. the objective of this study was to examine the acute suppression effect of lg tea on bgl rise in disaccharide-loaded sprague-dawley (sd) rats and to ev ... | 2010 | 20355112 |
| effects of eriobotrya japonica seed extract on oxidative stress in rats with non-alcoholic steatohepatitis. | non-alcoholic steatohepatitis is associated with the deposition of lipid droplets in the liver, and is characterised histologically by the infiltration of inflammatory cells, hepatocellular degeneration and liver fibrosis. oxidative stress may play an important role in the onset and deterioration of non-alcoholic steatohepatitis. we previously reported that an eriobotrya japonica seed extract, extracted in 70% ethanol, exhibited antioxidant actions in vitro and in vivo. in this study, we examine ... | 2010 | 20487204 |
| immunomodulatory effect of eriobotrya japonica seed extract on allergic dermatitis rats. | we examined the immunomodulatory effect of eriobotrya japonica seed extract (ese) on rat allergic dermatitis elicited by repeated dinitrofluorobenzene (dnfb) application on the ear. oral administration of ese significantly inhibited development of allergic dermatitis based on lower ear thickness and serum immunoglobulin e (ige) levels. th1 cytokine interferon-gamma (ifn-gamma) and interleukin-2 (il-2), th2 cytokine interleukin-4 (il-4) and interleukin-10 (il-10) in the lesional skin were determi ... | 2010 | 20495297 |
| determining total phenolic content and total antioxidant capacity of loquat cultivars grown in hatay. | several fruit characteristics of five loquat (eriobotrya japonica (thunb.) lindl.) cultivars/selections grown in dörtyol, hatay, turkey were investigated in 2008. the cultivars/selections included 'baduna 5', güzelyurt 1, 'hafif cukurgöbek', 'ottaviani,' and type 1. the characteristics evaluated included fruit weight, width, length, seed number and weight, flesh/seed ratio, total soluble solids (tss), ph, acidity, total phenolic (tp) content, and total antioxidant capacity (tac), determined by t ... | 2010 | 20548929 |
| identification of alpha-glucosidase inhibitors from a new fermented tea obtained by tea-rolling processing of loquat (eriobotrya japonica) and green tea leaves. | a new fermented tea produced by tea-rolling processing of loquat (eriobotrya japonica) leaf with green tea leaf (denoted as lg tea) showed a potent antihyperglycaemic effect in maltose-loaded rats. the aim of this study, therefore, was to identify alpha-glucosidase inhibitors in the antihyperglycaemic tea product. | 2010 | 20549810 |
| eriobotrya japonica improves hyperlipidemia and reverses insulin resistance in high-fat-fed mice. | the effect of eriobotrya japonica lindl. (loquat) on insulin resistance was examined in mice fed a high-fat (hf) diet. first, the mice were divided randomly into two groups: the control (con) group was fed a low-fat diet, whereas the experimental group was fed with a 45% hf diet for 10 weeks. after 6 weeks of induction, the hf group was subdivided into five groups and was given orally loquat or not for 4 weeks afterward. it was demonstrated that loquat was effective in ameliorating the hf diet-i ... | 2010 | 20564460 |
| eriobotrya japonica seed extract and deep sea water protect against indomethacin-induced gastric mucosal injury in rats. | we have previously reported that eriobotrya japonica seed extract (ese) is effective for the treatment of various gastric mucosal injuries. for the pharmaceutical preparation of ese, we are evaluating deep sea water (dsw), which contains trace elements and has a homeostasis-enhancing effect, as the solvent. in this study, we prepared dsw containing ese (ese + dsw) and evaluated its usefulness for the prevention of gastric mucosal injuries using non-steroidal anti-inflammatory drug-induced acute ... | 2011 | 20640522 |
| effect of 1-methylcyclopropene on anthracnose rot caused by colletotrichum acutatum and disease resistance in loquat fruit. | backgound: loquat (eriobotrya japonica lindl.) fruit are susceptible to fungal decay during postharvest storage at ambient temperature. the control of postharvest diseases of loquat is based primarily on the use of synthetic fungicides. to look for an alternative method for disease control, we investigated the effect of 1-methylcyclopropene (1-mcp) on controlling anthracnose rot caused by colletotrichum acutatum of loquat fruit. results: 1-mcp treatment significantly reduced decay incidence of l ... | 2010 | 20648530 |
| hypotriacylglycerolemic and antiobesity properties of a new fermented tea product obtained by tea-rolling processing of third-crop green tea (camellia sinensis) leaves and loquat (eriobotrya japonica) leaves. | we manufactured a new fermented tea by tea-rolling processing of third-crop green tea (camellia sinensis) leaves and loquat (eriobotrya japonica) leaves. the mixed fermented tea extract inhibited pancreatic lipase activity in vitro, and effectively suppressed postprandial hypertriacylglycerolemia in rats. rats fed a diet containing 1% freeze-dried fermented tea extract for 4 weeks had a significantly lower liver triacylglycerol concentration and white adipose tissue weight than those fed the con ... | 2010 | 20699580 |
| repeated-dose (28 days) oral toxicity study in rats of an antiacne formula (bc-af) derived from plants. | to evaluate the safety of a formula (bc-af) consisting of the extracts of danshen (salvia miltiorrhiza), loquat leaf (glycyrrhiza uralensis), and licorice (eriobotrya japonica), a preliminary 28-day, repeated-dose oral toxicity study was performed in sprague-dawley rats. eighty animals were divided into four groups, with each group comprising 10 male and 10 female rats. bc-af was administered once-daily by oral gavage at doses of 0 (control), 2.5 (low), 5 (middle), and 10 (high) g/kg body weight ... | 2010 | 20954811 |
| neuroprotective effects of eriobotrya japonica against β-amyloid-induced oxidative stress and memory impairment. | the generation of oxygen free radicals and oxidative damage is believed to be involved in the pathogenesis of neurodegenerative disorders. eriobotrya japonica has been used to treat several diseases in east asia. in this study, we investigated the protective effect of an e. japonica extract against aβ peptide-induced oxidative stress. the 1,1-diphenyl-2-picrylhydrazyl (dpph) assay demonstrated that the e. japonica extract scavenged approximately 40% of dpph radicals. also, treatment of the e. ja ... | 2010 | 21168467 |
| anti-inflammatory and antinociceptive properties of the leaves of eriobotrya japonica. | the leaves of eriobotrya japonica lindl. have been widely used as a traditional medicine for the treatment of many diseases including coughs and asthma. the present study was designed to validate the anti-inflammatory and antinociceptive properties of the n-buoh fraction of e. japonica (lej) leaves. | 2010 | 21182921 |
| ameliorative effects of eriobotrya japonica seed extract on cellular aging in cultured rat fibroblasts. | to investigate the effects of eriobotrya japonica seed extract (ese) on cellular aging, intracellular calcium homeostasis in young and senescent cells was analyzed using a rat fibroblast culture as an in vitro model system and a calcium imaging technique. the application of bradykinin (bk) transiently elicited intracellular calcium ion (ca(2+)) increased in most of the young fibroblasts, whereas these responses were scarcely observed or were significantly attenuated in senescent cells. however, ... | 2010 | 21188645 |
| eriobotrya japonica hydrophilic extract modulates cytokines in normal tissues, in the tumor of meth-a-fibrosarcoma bearing mice, and enhances their survival time. | cytokines play a key role in the immune response to developing tumors, and therefore modulating their levels and actions provides innovative strategies for enhancing the activity of antigen presenting cells and polarizing towards t helper 1 type response within tumor microenvironment. one of these approaches could be the employment of plant extracts that have cytokine immunomodulation capabilities. previously, we have shown that the eriobotrya japonica hydrophilic extract (ejhe) induces proinfla ... | 2011 | 21294856 |
| 3-o-(e)-p-coumaroyl tormentic acid from eriobotrya japonica leaves induces caspase-dependent apoptotic cell death in human leukemia cell line. | eleven triterpene acids, 1-11, isolated from the leaves of eriobotrya japonica, were evaluated for inhibition of dna topoisomerase (topo) i and cytotoxicity against human leukemia (hl60) and melanoma cell lines (crl1579). among the compounds tested, four compounds, d-oleanolic acid (4), ursolic acid (5), 3-o-(e)-p-coumaroyl tormentic acid (8), and betulinic acid (10), exhibited potent topo i inhibitory activity (ic(50) 20.3-36.5 µm) and cytotoxicity against hl60 (ec(50) 5.0-8.1 µm). upon assessi ... | 2011 | 21372421 |
| protective changes of inflammation-related gene expression by the leaves of eriobotrya japonica in the lps-stimulated human gingival fibroblast: microarray analysis. | the leaf of eriobotrya japonica (ej) has been used for a long time as an oriental medicine to treat pulmonary inflammatory diseases. this study investigated the gene expression changes by lipopolysaccharide (lps) stimulation in the cultured human gingival fibroblast and the anti-inflammatory changes of the genes by the leaves of ej when challenged with lps using a microarray chip. | 2011 | 21473904 |
| anti-metastatic properties of the leaves of eriobotrya japonica. | the leaves of eriobotrya japonica lindl. have been widely used as a traditional medicine for the treatment of many diseases including gastroenteric disorders, diabetes mellitus, chronic bronchitis and asthma. in the present study, the anti-metastatic action of the etoac fraction of the leaves of e. japonica (lej) was investigated. lej showed potent inhibitory effects on mmp-2 and mmp-9 activities and expressions via down-regulation of nf-κb translocation to the nucleus in b16f10 cells. in additi ... | 2011 | 21547674 |
| screening of estrogenic and antiestrogenic activities from medicinal plants. | the medicinal plant extracts commercially used in asia were screened for their estrogenic and antiestrogenic activities in a recombinant yeast system featuring both a human estrogen receptor (er) expression plasmid and a reporter plasmid. pueraria lobata (flower) had the highest estrogenic relative potency (rp, 7.75+ù10(-3); rp of 17+¦-estradiol=1), followed by amomum xanthioides (1.25+ù10(-3)). next potent were a group consisting of glycyrrhiza uralensis, zingiber officinale, rheum undulatum, c ... | 2008 | 21783839 |
| enhancement of eriobotrya japonica extracts on non-specific immune response and disease resistance in kelp grouper epinephelus bruneus against vibrio carchariae. | the present study investigated the effect of eriobotrya japonica extracts at 0%, 0.1%, 1.0%, and 2.0% doses supplementation with feed on non-specific immune response, hematological and biochemical profile, and disease resistance against vibrio carchariae in kelp grouper epinephelus bruneus at weeks 1, 2, and 4. the white blood cell (wbc) significantly increased in fish fed with 0.1%, 1.0%, and 2.0% diets on weeks 1 and 2 when compared to the control. however, the glucose always decreased from th ... | 2011 | 22032903 |
| isolation and antimicrobial and antioxidant evaluation of bio-active compounds from eriobotrya japonica stems. | the present study was carried out to evaluate antimicrobial and antioxidant activities from eriobotrya japonica stems as well investigation of its chemical composition. | 2014 | 24409413 |
| characterization of an o-methyltransferase specific to guaiacol-type benzenoids from the flowers of loquat (eriobotrya japonica). | volatile benzenoids, including methyl p-methoxybenzoate, p-anisaldehyde, and p-anisalcohol, are responsible for the sweet and characteristic fragrance of loquat (eriobotrya japonica, rosaceae) flowers. although the full pathway of volatile benzenoid synthesis has yet to be elucidated, their chemical structures suggest that o-methyltransferases are present in loquat and function in the methylation of the para-oh groups. in the present study, we used rna-sequencing to identify four loquat genes (e ... | 2016 | 27473288 |
| benzenoid biosynthesis in the flowers of eriobotrya japonica: molecular cloning and functional characterization of p-methoxybenzoic acid carboxyl methyltransferase. | p -methoxybenzoic acid carboxyl methyltransferase (mbmt) was isolated from loquat flowers. mbmt displayed high similarity to jasmonic acid carboxyl methyltransferases, but exhibited high catalytic activity to form methyl p -methoxybenzoate from p -methoxybenzoic acid. volatile benzenoids impart the characteristic fragrance of loquat (eriobotrya japonica) flowers. here, we report that loquat produces methyl p-methoxybenzoate, along with other benzenoids, as the flowers bloom. although the adaxial ... | 2016 | 27146420 |
| ejodo1, a myb transcription factor, regulating lignin biosynthesis in developing loquat (eriobotrya japonica) fruit. | lignin is important for plant secondary cell wall formation and participates in resistance to various biotic and abiotic stresses. loquat undergoes lignification not only in vegetative tissues but also in flesh of postharvest fruit, which adversely affects consumer acceptance. thus, researches on lignin biosynthesis and regulation are important to understand loquat fruit lignification. in loquat, a gene encoding an enzyme in the lignin biosynthesis pathway, ej4cl1, was reported to be regulated b ... | 2016 | 27695460 |
| regulation of loquat fruit low temperature response and lignification involves interaction of heat shock factors and genes associated with lignin biosynthesis. | transcriptional regulatory mechanisms underlying lignin metabolism have been widely studied in model plants and woody trees, as well as fruit, such as loquat (eriobotrya japonica). unlike the well-known nac, myb and ap2/erf transcription factors, the roles of heat shock factors (hsfs) in lignin regulation have been rarely reported. two treatments (heat treatment, ht; low temperature conditioning, ltc) were applied to alleviate low temperature-induced lignification in loquat fruit. gene expressio ... | 2016 | 27006258 |
| ejap2-1, an ap2/erf gene, is a novel regulator of fruit lignification induced by chilling injury, via interaction with ejmyb transcription factors. | lignin biosynthesis is regulated by many transcription factors, such as those of the myb and nac families. however, the roles of ap2/erf transcription factors in lignin biosynthesis have been rarely investigated. eighteen ejap2/erf genes were isolated from loquat fruit (eriobotrya japonica), which undergoes postharvest lignification during low temperature storage. among these, expression of ejap2-1, a transcriptional repressor, was negatively correlated with fruit lignification. the dual-lucifer ... | 2015 | 25778106 |
| chemical composition of different botanical origin honeys produced by sicilian black honeybees (apis mellifera ssp. sicula). | in 2008 a slow food presidium was launched in sicily (italy) for an early warning of the risk of extinction of the sicilian native breed of black honeybee (apis mellifera l. ssp sicula). today, the honey produced by these honeybees is the only sicilian honey produced entirely by the black honeybees. in view of few available data regarding the chemical composition of a. mellifera ssp. sicula honeys, in the present investigation the chemical compositions of sulla honey (hedysarum coronarium l.) an ... | 2015 | 25730368 |
| increase of theaflavin gallates and thearubigins by acceleration of catechin oxidation in a new fermented tea product obtained by the tea-rolling processing of loquat ( eriobotrya japonica ) and green tea leaves. | in a project to produce a new fermented tea product from non-used tea leaves harvested in the summer, we found that kneading tea leaves ( camellia sinensis ) with fresh loquat leaves ( eriobotrya japonica ) accelerated the enzymatic oxidation of tea catechins. the fermented tea obtained by tea-rolling processing of tea and loquat leaves had a strong, distinctive flavor and a plain aftertaste, which differed from usual black, green, and oolong teas. the phenolic constituents were similar to those ... | 2009 | 19507893 |
| study on the mechanisms of the bronchodilator effects of folium eriobotryae and the selected active ingredient on isolated guinea pig tracheal strips. | folium eriobotryae (fe), the dry leaf of eriobotrya japonica (thunb.) lindl. (rosaceae), has been widely used to treat respiratory disorders. | 2016 | 27251608 |
| host susceptibility of citrus cultivars to queensland fruit fly (diptera: tephritidae). | citrus crops are considered to be relatively poor hosts for queensland fruit fly, bactrocera tryoni (froggatt), as for other tephritid species. australian citrus growers and crop consultants have reported observable differences in susceptibility of different citrus cultivars under commercial growing conditions. in this study we conducted laboratory tests and field surveys to determine susceptibility to b. tryoni of six citrus cultivars [(eureka lemon (citrus limon (l.) osbeck); navel and valenci ... | 2013 | 23786078 |
| [effects of different planting modes on the soil permeability of sloping farmlands in purple soil area]. | taking bare land as the control, this paper studied the effects of different planting modes on the soil permeability of sloping farmlands in purple soil area. for the test six planting modes, the soil permeability was in the order of eriobotrya japonica > citrus limon > vetiveria zizanioides hedgerows +corn >leucaena leucocephala hedgerows + corn> hemerocallis fulva > corn> bare land, and decreased with increasing depth. the eigenvalues of soil infiltration were in the order of initial infiltrat ... | 2013 | 23755487 |
| isolation and characterization of a catalase gene "hucat3" from pitaya (hylocereus undatus) and its expression under abiotic stress. | abiotic stresses usually cause h2o2 accumulation, with harmful effects, in plants. catalase may play a key protective role in plant cells by detoxifying this excess h2o2. pitaya (hylocereus undatus) shows broad ecological adaptation due to its high tolerance to abiotic stresses, e.g. drought, heat and poor soil. however, involvement of the pitaya catalase gene (hucat) in tolerance to abiotic stresses is unknown. in the present study, a full-length hucat3 cdna (1870 bp) was isolated from pitaya b ... | 2015 | 25752288 |
| total phenolic contents and antioxidant capacities of selected chinese medicinal plants. | antioxidant capacities of 56 selected chinese medicinal plants were evaluated using the trolox equivalent antioxidant capacity (teac) and ferric reducing antioxidant power (frap) assays, and their total phenolic content was measured by the folin-ciocalteu method. the strong correlation between teac value and frap value suggested that the antioxidants in these plants possess free radical scavenging activity and oxidant reducing power, and the high positive correlation between antioxidant capaciti ... | 2010 | 20640157 |
| acute and subacute oral toxicity evaluation of eriobotrya japonica leaf triterpene acids in icr mice. | the interest focusing on eriobotrya japonica leaf triterpene acid (elta) has increased recently because of its beneficial effects on health. however, there has been a lack of experimental data on its toxicity. the present study therefore was conducted to evaluate its toxicity in icr mice. the results showed that elta produced neither mortality nor toxicity of the main organs in icr male and female mice in both acute (0.30, 0.65, 1.39, and 3.00 g·kg(-1) body weight) and subacute (150, 300, and 60 ... | 2017 | 28400843 |
| bioactive triterpenoids from the leaves of eriobotrya japonica as the natural pde4 inhibitors. | the ethanolic extract of the leaves of eriobotrya japonica exhibited inhibitory activity against phosphodiesterase-4d (pde4d), which is a therapeutic target of inflammatory disease. subsequent bioassay-guided fractionation led to the isolation of a new triterpene (1), together with seven known triterpenoids, methyl corosolate (2), ursolic acid (3), oleanolic acid (4), methyl maslinate (5), α-amyin (6), 3β,19α,23-trihydroxy-urs-12-ene (7) and uvaol (8). the structure of compound 1 was established ... | 2017 | 28281360 |
| ethylene biosynthesis and perception during ripening of loquat fruit (eriobotrya japonica lindl.). | in order to gain insights into the controversial ripening behavior of loquat fruits, in the present study we have analyzed the expression of three genes related to ethylene biosynthesis (acs1, aco1 and aco2), two ethylene receptors (ers1a and ers1b), one signal transduction component (ctr1) and one transcription factor (eil1) in peel and pulp of loquat fruit during natural ripening and also in fruits treated with ethylene (10μll(-1)) and 1-mcp (10μll(-1)), an ethylene action inhibitor. in fruits ... | 2017 | 28088087 |
| transcriptome analysis reveals candidate genes involved in gibberellin-induced fruit setting in triploid loquat (eriobotrya japonica). | the triploid loquat (eriobotrya japonica) is a new germplasm with a high edible fruit rate. under natural conditions, the triploid loquat has a low fruit setting ratio (not more than 10 fruits in a tree), reflecting fertilization failure. to unravel the molecular mechanism of gibberellin (ga) treatment to induce parthenocarpy in triploid loquats, a transcriptome analysis of fruit setting induced by ga3 was analyzed using rna-seq at four different stages during the development of young fruit. app ... | 2016 | 28066478 |
| complete plastid genome of eriobotrya japonica (thunb.) lindl and comparative analysis in rosaceae. | eriobotrya japonica (thunb.) lindl (loquat) is an evergreen rosaceae fruit tree widely distributed in subtropical regions. its leaves are considered as traditional chinese medicine and are of high medical value especially for cough and emesis. thus, we sequenced the complete plastid genome of e. japonica to better utilize this important species. the complete plastid genome of e. japonica is 159,137 bp in length, which contains a typical quadripartite structure with a pair of inverted repeats (ir ... | 2016 | 27995013 |
| biological activities of extracts from loquat (eriobotrya japonica lindl.): a review. | loquat (eriobotrya japonica lindl.) is a subtropical fruit tree with high medicinal value native to china. different organs of loquat have been used historically as folk medicines and this has been recorded in chinese history for thousands of years. research shows that loquat extracts contain many antioxidants, and different extracts exhibit bioactivity capable of counteracting inflammation, diabetes, cancer, bacterial infection, aging, pain, allergy and other health issues. bioactive compounds ... | 2016 | 27929430 |
| comparative transcriptional analysis of loquat fruit identifies major signal networks involved in fruit development and ripening process. | loquat (eriobotrya japonica lindl.) is an important non-climacteric fruit and rich in essential nutrients such as minerals and carotenoids. during fruit development and ripening, thousands of the differentially expressed genes (degs) from various metabolic pathways cause a series of physiological and biochemical changes. to better understand the underlying mechanism of fruit development, the solexa/illumina rna-seq high-throughput sequencing was used to evaluate the global changes of gene transc ... | 2016 | 27827928 |
| induced parthenogenesis by gamma-irradiated pollen in loquat for haploid production. | successful haploid induction in loquat (eriobotrya japonica (thunb.) lindl.) through in situ-induced parthenogenesis with gamma-ray irradiated pollen has been achieved. female flowers of cultivar 'algerie' were pollinated using pollen of cultivars 'changhong-3', 'cox' and 'saval brasil' irradiated with two doses of gamma rays, 150 and 300 gy. the fruits were harvested 90, 105 and 120 days after pollination (dap). four haploid plants were obtained from 'algerie' pollinated with 300-gy-treated pol ... | 2016 | 27795686 |
| evaluation of antioxidant activity of loquat fruit (eriobotrya japonica lindl.) skin and the feasibility of their application to improve the oxidative stability of soybean oil. | the effects of ultrasound-assisted, supercritical co2 and solvent extraction techniques on antioxidant activity of loqua (eriobotrya japonica lindl.) skin extract in oxidation stability of soybean oil was evaluated. the antioxidant efficacy of extracts was determined using 2, 2-diphenyl-1-picrylhydrazyl (dpph(•)) radical scavenging capacity, β-carotene/linoleic acid, and rancimat test system. results showed that solvent extract of loquat fruit skin at 400 ppm had the highest antioxidant activity ... | 2016 | 27407190 |
| pomological traits, sensory profile and nutraceutical properties of nine cultivars of loquat (eriobotrya japonica lindl.) fruits grown in mediterranean area. | in this paper the diversity of fruit quality within nine loquat cultivars, including five international affirmed cultivars (algerie, golden nugget, peluche, bueno, el buenet) and four local cultivars (sanfilippara, nespolone di trabia, brt20 and claudia), were investigated in order to discriminate the variation in pomological characteristics, sensory profile, and antioxidant properties. finally, to evaluate potential bioactivity, antiproliferative activity of hydrophilic extracts from loquat fru ... | 2016 | 27392960 |
| inhibitory effect of ursolic acid and oleanolic acid from eriobotrya fragrans on a549 cell viability in vivo. | loquat [eriobotrya japonica (lindl.)] is a traditional chinese medicine, which has been used as an anti-inflammatory and for curing chronic bronchitis among other potential applications. extracted ursolic acid (ua) and oleanolic acid (oa) from wild loquat were previously found capable of suppressing the proliferation of a549 cells in vitro. in the current study, nude mice were used to determine the inhibitory effect of ua and oa on tumor formation in vivo. the results demonstrate that ua and oa ... | 2016 | 27323036 |
| eriobotrya japonica water extract characterization: an inducer of interferon-gamma production mainly by the jak-stat pathway. | eriobotrya japonica (thunb.) lindl. (loquat) (ej) has been used as a medicinal plant to treat chronic bronchitis, coughs, phlegm, high fever and gastro-enteric disorders. since the traditional use of ej is related to modulating inflammation processes, our earlier studies on ej leaves were performed on the water extract to investigate specific cytokines' modulation. these earlier studies, however, have shown that ej leaf water extract (we) and the water phase (wp) induce cytokines' production in ... | 2016 | 27271577 |
| loquat (eriobotrya japonica) leaf extract inhibits the growth of mda-mb-231 tumors in nude mouse xenografts and invasion of mda-mb-231 cells. | the present study was conducted to examine the inhibitory effect of loquat leaves on mda-mb-231 cell proliferation and invasion. | 2016 | 27087896 |
| eriobotrya japonica seed biocomposite efficiency for copper adsorption: isotherms, kinetics, thermodynamic and desorption studies. | adsorption techniques are widely used to remove pollutants from wastewater; however, composites are gaining more importance due to their excellent adsorption properties. bentonite composite with eriobotrya japonica seed was prepared and used for the adsorption of copper (cu) metal from aqueous media. the process variables such as ph, cu(ii) ions initial concentration, adsorbent dose, contact time and temperature were optimized for maximum cu(ii) adsorption. at ph 5, adsorbent dose 0.1 g, contact ... | 2016 | 27039361 |
| effects of standardized eriobotrya japonica extract in lp-bm5 murine leukemia viruses-induced murine immunodeficiency syndrome. | folk medicine has long employed leaves from eriobotrya japonica lindl. (rosaceae) (lej) as relieving many diseases including chronic bronchitis and high fever. in this study, we investigated the immunomodulatory effects of leaves from lej water extracts (leje) in lp-bm5 murine leukemia viruses (mulv)-induced immune-deficient animal model. dietary supplementation of leje (100, 300, 500 mg/kg) began on the day of lp-bm5 mulv infection and continued for 12 weeks. dietary supplementation of leje inh ... | 2016 | 26854821 |
| erratum: influence of extraction techniques on antioxidant properties and bioactive compounds of loquat fruit (eriobotrya japonica lindl.) skin and pulp extracts. | [this corrects the article doi: 10.1002/fsn3.201.]. | 2015 | 26788304 |
| erratum: antioxidative effect of loquat (eriobotrya japonica lindl.) fruit skin extract in soybean oil. | [this corrects the article doi: 10.1002/fsn3.193.]. | 2015 | 26788303 |
| an integrated global chemomics and system biology approach to analyze the mechanisms of the traditional chinese medicinal preparation eriobotrya japonica - fritillaria usuriensis dropping pills for pulmonary diseases. | traditional chinese medicine (tcm) herbal formulae provide valuable therapeutic strategies. however, the active ingredients and mechanisms of action remain unclear for most of these formulae. therefore, the identification of complex mechanisms is a major challenge in tcm research. | 2016 | 26742634 |
| analysis of genomic dnas from nine rosaceae species using surface-enhanced raman scattering. | surface-enhanced raman scattering (sers) of genomic dna was used to determine genetic relationships and species identification of nine plants from three subfamilies of rosaceae. genomic dna was extracted, and the sers spectra were obtained by using a nanosilver collosol at an excitation wavelength of 785 nm. adenine and ribodesose were the active sites of genomic dnas in the silver surface-enhanced raman spectra. the strong peak at 714 cm(-1) was assigned to the stretching vibration of adenine, ... | 2015 | 26555541 |
| new sesquiterpene glycosides from the leaves of eriobotrya japonica. | one new sesquiterpene glycoside, named nerolidol-3-o-α-l-rhamnopyranosyl-(1 --> 6)-β-d-glucopyranoside (1), along with one novel natural product nerolidol-3-o-α-l-rhamnopyranosyl-(1 --> 2)-[α-l-rhamnopyranosyl-(1 --> 6)]-β-d-glucopyranoside (2) and two known sesquiterpene glycosides (3-4), were isolated from the leaves of eriobotrya japonica (thunb.) lindl.. their structures were elucidated on the basis of 1d, 2d nmr and hr-ms data. the chemotaxonomic significance of this type of constituents wa ... | 2015 | 26410996 |