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sequence diversity of hepatitis c virus 6a within the extended interferon sensitivity-determining region correlates with interferon-alpha/ribavirin treatment outcomes.studies on the association between sequence variability of the interferon sensitivity-determining region (isdr) of hepatitis c virus and the outcome of treatment have reached conflicting results. in this study, 25 patients infected with hcv 6a who had received interferon-alpha/ribavirin combination treatment were analyzed for the sequence variations. 14 of them had the full genome sequences obtained from a previous study, whereas the other 11 samples were sequenced for the extended isdr (eisdr). ...201020624431
a possible geographic origin of endemic hepatitis c virus 6a in hong kong: evidences for the association with vietnamese immigration.hepatitis c virus (hcv) 6a accounts for 23.6% of all hcv infections of the general population and 58.5% of intravenous drug users in hong kong. however, the geographical origin of this highly predominant hcv subgenotype is largely unknown. this study explores a hypothesis for one possible transmission route of hcv 6a to hong kong.201121931867
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