| immunologic relationship between rinderpest and peste des petits ruminants viruses. | | 1975 | 86993 |
| experimental infection of nigerian sheep and goats with bovine virus diarrhoea virus. | apart from leucopenia and a low grade pyrexia nigerian goats showed no ill effects following inoculation with bovine virus diarrhoea virus. sheep showed a variable leucopenia without pyrexia. no difficulty should arise in differentiating bvd infections from peste des petits ruminants. | 1977 | 202049 |
| the isolation of adenoviruses from goats affected with peste des petits ruminants in nigeria. | mucosal scrapings from the large intestine of two goats that had died from peste des petits ruminants (ppr) in separate outbreaks in nigeria were examined for viruses. a mixed viral infection of ppr virus (morbillivirus) and adenovirus was confirmed in both goats. the adenoviruses did not conform to any of the ovine and bovine serotypes recognised; the two isolates were considered different serotypes. it is concluded that, although the role of adenoviruses in the epizootiology of ppr in nigeria ... | 1977 | 203986 |
| susceptibility of mink to certain viral animal diseases foreign to the united states. | mink (mustela vison) were inoculated with viruses: african horse sickness (ahs), african swine fever (asf), bovine herpes virus ii (bhv2), foot-and-mouth disease (fmd), goat pox (gp), hog cholera (hc), peste des petits ruminants (ppr), rinderpest (rp), swine vesicular disease (svd), vesicular exanthema of swine (ves) and vesicular stomatitis (vs). their susceptibility was measured by development of clinical signs, virus isolation and detection of precipitin and/or virus neutralizing antibodies. ... | 1979 | 228092 |
| serological studies with the virus of peste des petits ruminants in nigeria. | it was possible to distinguish separate serological responses when experimental goats were inoculated with either rinderpest virus or peste des petits ruminants virus. examination of field samples established that peste des petits ruminants occur commonly in nigerian sheep and goats although some villages have escaped recent infection. there was no evidence of infection with rinderpest in these animals. | 1979 | 262608 |
| classification of peste des petits ruminants virus as the fourth member of the genus morbillivirus. | peste des petits ruminants (ppr) is a virus disease of sheep and goats in west africa. when first described, the virus was considered a variant of rinderpest virus. the biological and physicochemical characteristics of the virus indicate that it is closely related to measles, rinderpest and canine distemper viruses. these three viruses form the genus morbillivirus of the paramyxoviridae. ppr virus is sufficiently distinct from these 3 viruses to justify considering it as the fourth member of the ... | 1979 | 457363 |
| experimental infection of domestic pigs with the virus of peste des petits ruminants. | pigs could be subclinically infected with pprv by inoculation or contact with infected goats. there was no evidence that the virus could spread to uninfected pigs or goats and pigs are not considered important in the epidemiology of pprv. | 1979 | 462558 |
| the isolation of peste des petits ruminants virus from nigerian sheep and goats. | four isolates of peste des petits ruminants virus were obtained from sick nigerian sheep and goats. one was identical antigenically with the prototype senegalese strain. a cross relationship was found between peste des petits ruminants virus and rinderpest virus based on neutralisation in vitro. | 1979 | 472495 |
| protection of goats against peste-des-petits-ruminants with attenuated rinderpest virus. | goats vaccinated with attenuated rinderpest were protected from peste-des-petits-ruminants virus for at least 12 months; vaccinated animals were unable to transmit the challenge virus. before challenge neutralising antibodies were directed primarily against rinderpest but following exposure to peste-des-petits-ruminants, a high antibody level to both viruses was found. | 1979 | 542719 |
| orf in sheep and goats in nigeria. | orf virus was demonstrated in biopsy material taken from lambs during an outbreak of the disease on the university of ibadan teaching and research farm. clinical cases were also seen in goats. the confirmation of orf in nigeria is discussed in relation to peste des petits ruminants, an important virus disease of small ruminants in west african countries. | 1978 | 746590 |
| etiology of the stomatitis pneumoenteritis complex in nigerian dwarf goats. | the causative agent of stomatitis pneumoenteritis complex was isolated in domesticated goats and vero cell culture. it was identified immunologically and morphologically as identical with the "peste des petits ruminants" virus. there were cross reactions between stomatitis pneumoenteritis complex virus isolate and rinderpest virus by immunodiffusion and complement fixation tests but no cross neutralization. goats recovered from stomatitis pneumoenteritis complex were protected against a challeng ... | 1976 | 826310 |
| haemagglutination-inhibition technique for definitive diagnosis of rinderpest-virus-specific antibody. | a simple and rapid serological method for the definitive diagnosis of rinderpest-specific antibody is described. the technique is based on adsorbing out the cross reacting antibodies to peste des petits ruminants antigens from a rinderpest immune serum, thereby leaving active the specific antibody to rinderpest which is determined by haemagglutination-inhibition test. | 1992 | 1298202 |
| serological survey for bovine bacterial and viral pathogens in captive arabian oryx (oryx leucoryx pallas, 1776). | tests for antibodies to bovine bacterial and viral pathogens were conducted on 239 sera from 128 arabian oryx (oryx leucoryx) from seven locations (taif, riyadh and mahazat as said, saudi arabia; san diego, united states of america [usa]; shaumari, jordan; qatar; and bahrain). no antibodies to pasteurella multocida type e or epizootic haemorrhagic disease 1 virus were found. antibodies to brucella abortus, p. multocida type b, p. multocida type d, lumpy skin disease virus and akabane virus were ... | 1992 | 1305861 |
| improved isolation of rinderpest virus in transformed bovine t lymphoblast cell lines. | bovine t lymphoblast cell lines transformed by the protozoan theileria parva were compared with bovine kidney (bk) and vero cells for their ability to isolate various strains of rinderpest virus from tissues and infected secretions. all of the strains of rinderpest virus that were tested, including attenuated cell-culture, caprinised and lapinised vaccines, and both mild and virulent pathogenic strains, readily induced syncytial cytopathic effect (cpe) in t lymphoblasts. the cpe could often be d ... | 1992 | 1410806 |
| round table on morbilliviruses in marine mammals. | since 1988 morbilliviruses have been increasingly recognized and held responsible for mass mortality amongst harbour seals (phoca vitulina) and other seal species. virus isolations and characterization proved that morbilliviruses from seals in northwest europe were genetically distinct from other known members of this group including canine distemper virus (cdv), rinderpest virus, peste des petits ruminants virus and measles virus. an epidemic in baikal seals in 1987 was apparently caused by a m ... | 1992 | 1481361 |
| phocine distemper virus, the agent responsible for the 1988 mass mortality of seals. | the biochemical characterisation of phocine distemper virus (pdv) has shown that pdv is related to but clearly distinct from canine distemper virus (cdv) and relative to its relationship with cdv is only remotely related to the other morbilliviruses, namely measles virus (mv) or rinderpest virus (rpv) and peste-des-petits-ruminants virus (pprv). comparative studies with monoclonal antibodies indicate that the virus is serologically closely related to cdv with many conserved epitopes, particularl ... | 1992 | 1594934 |
| a competitive elisa using anti-n monoclonal antibodies for specific detection of rinderpest antibodies in cattle and small ruminants. | a competitive elisa (c-elisa) using monoclonal antibodies (mabs) which bind to the nucleo-protein (np) of rinderpest virus (rpv) for detection of rpv antibodies in cattle and small ruminant sera is described. unlike virus neutralisation test (vnt), this test using mab ivb2-4, can detect specific rpv antibodies without showing a cross-reaction with antibodies to peste-des-petits ruminants-virus (pprv); by contrast, when mab ve4-1 is used the test detects both rpv and pprv antibodies, including lo ... | 1992 | 1626365 |
| identification of epitope(s) on the internal virion proteins of rinderpest virus which are absent from peste des petits ruminants virus. | monoclonal antibodies (mab) raised against the rbok vaccine strain of rinderpest virus were characterized by radio-immunoprecipitation (ripa) and in the indirect elisa using measles (mv), distemper (cdv), rinderpest (rpv) and peste des petits ruminants viruses (pprv). those found to be specific for the matrix (m) protein and the nucleocapsid (n) protein could be classified into different groups on the basis of the anti-morbillivirus mab classification scheme; a number of these mab showed a selec ... | 1991 | 1709543 |
| [serological survey of small ruminants in 4 districts of niger]. | in 1990, a serosurvey on 1,474 small ruminants was conducted in four districts of niger (maradi, zinder, diffa and dosso). the epidemiology and seroprevalence of eight diseases were studied: brucella melitensis and b. ovis brucellosis, chlamydiosis, coxiellosis, contagious caprine pleuropneumonia, type a pasteurellosis, peste des petits ruminants, rift valley fever, crimée-congo haemorragic fever. the main health problem for the development of small ruminants farming, seems to be both pasteurell ... | 1991 | 1843821 |
| rapid isolation of monoclonal hybridoma cultures by a 'fusion-cloning' method: the requirement for aminopterin. | hybridomas were generated by fusing the balb/c sp2/0 myeloma-like cell line with either: (i) splenocytes from balb/c mice immunized with foot-and-mouth disease virus (fmdv), rinderpest virus (rpv), peste des petits ruminants virus (pprv), african swine fever virus (asfv) or pig thymocytes; or (ii) lymph node cells from cattle immunized with fmdv. if the fusion mixtures were plated in cloning medium of methyl cellulose and hat medium, small hybridoma colonies developed which rarely survived. fusi ... | 1991 | 1954000 |
| aerobic bacteria from nasal discharge of goats suffering from clinical ppr: isolation and identification. | bacteriological isolation of aerobic bacteria from nasal discharge of achondroplastic west african dwarf goats showing clinical signs of peste des petits ruminants (ppr), and the laboratory procedures carried out for the identification of the isolates are described. from a total of forty nasal swabs obtained seventy five isolates were recovered. the percentage frequency of isolation of different organisms in descending order of occurrence is as follows: staphylococcus 44.0%; streptococcus 22.67% ... | 1991 | 2023545 |
| serological evidence of peste des petits ruminants in jordan. | | 1991 | 2024417 |
| an immunohistochemical study of the pneumonia caused by peste des petits ruminants virus. | ten goats were inoculated with peste des petits ruminants virus, a paramyxovirus closely related to rinderpest virus. all goats developed severe clinical disease, 8/10 having coughing or dyspnea as prominent clinical signs. in addition, all of the goats had stomatitis and diarrhea. histopathologic and immunohistochemical studies were done only on the respiratory tracts. pathologic changes ranged from mild multifocal bronchiolitis and bronchitis to severe bronchointerstitial pneumonia. lesions we ... | 1991 | 2063517 |
| pathogenicity of peste des petits ruminants virus isolated from egyptian goats in egypt. | 2 egyptian goats and boscat rabbits were experimentally inoculated with peste des petits ruminants (ppr) local egyptian strain (ppr, egypt 87). the inoculated animals contracted the disease with minor clinical manifestations, accompanied by rise of neutralizing antibodies to ppr virus. virus was isolated from ocular and nasal secretions, buffy coat, spleen, and liver. no contact infection was observed between inoculated and healthy goats. | 1990 | 2096796 |
| the epidemiology of peste des petits ruminants in the sultanate of oman. | virological and serological evidence was obtained to show that peste des petits ruminants virus was widely distributed in omani sheep and goats. there was no evidence for the concomitant presence of rinderpest virus in these species. two virus isolates were classified as peste des petits ruminants virus on the basis of their pathogenicity in experimental animals and their specific hybridisation with nucleic acid probes. however, neutralisation tests and polyacrylamide gel analysis of their nucle ... | 1990 | 2114052 |
| peste des petits ruminants. | the peste des petits ruminants (ppr) is proving to be a disease which has an increasingly significant economic impact on a number of countries in africa and the middle east, and possibly also on the indian sub-continent. the antigenic relationships which exist between the ppr and rinderpest viruses pose problems for diagnosis which complicates rinderpest control and eradication programmes. progress has recently been made in regard to diagnosis (specific nucleic probes and monoclonal antibodies), ... | 1990 | 2132714 |
| optimal time for vaccination against peste des petits ruminants (ppr) disease in goats in humid tropical zone in southern nigeria. | investigation of the incidence of peste des petits ruminants (ppr) disease in goats revealed seasonality in the natural occurrence of ppr disease in the environment. tissue culture rinderpest vaccine was shown effective in protecting goats against the disease. the optimal time for vaccinating goats against ppr disease was when the least number of animals were incubating the disease. in the tropical humid zone, as in west africa, the optimal time for vaccination against the ppr disease is from la ... | 1990 | 2134153 |
| isolation of peste des petits ruminants from goats in saudi arabia. | | 1990 | 2238415 |
| evidence of identification of peste des petits ruminants from goats in egypt. | peste des petits ruminants virus was isolated from young goats in an outbreak of the disease for the first time in egypt. affected goats showed symptoms simulating rinderpest, disease in cattle. the mortality rate was about 30%, and morbidity reached 90%. history, clinical symptoms, postmortem lesions, and diagnosis were discussed. | 1990 | 2241482 |
| comparison of rinderpest and peste des petits ruminants viruses using anti-nucleoprotein monoclonal antibodies. | monoclonal antibodies (mabs) were obtained using a purified preparation of the rbok strain of a rinderpest vaccine virus. the cytoplasmic immunofluorescent staining test showed that these clones had specificity for the nucleoprotein (n) of the virus. six clones which immunoprecipitated the n protein corroborated these results. thirteen anti-n mabs were used to compare geographically widespread rinderpest viruses (rpv) and peste des petits ruminants viruses (pprv) to two other morbilliviruses, me ... | 1990 | 2247932 |
| pathogenicity of attenuated peste des petits ruminants virus in sheep and goats. | progressive loss of virulence for goat kids was noticed when peste des petits ruminants (ppr) virus was passaged in vero cells. while goats inoculated with the 60th passage suffered from the clinical ppr disease and mortality, goats inoculated with the 80th passage did not show any sign of the disease. if the progressive loss of virulence of the virus with passage continues, it will not be long before a homologous ppr vaccine will be obtained at the national veterinary institute, vom. | 1990 | 2263739 |
| the production of peste des petits ruminants hyperimmune sera in rabbits and their application in virus diagnosis. | hyperimmune sera were produced by serial inoculation of rabbits with vero cell-adapted, sucrose gradient-purified nigerian peste des petits ruminants virus (pprv) isolate. two antisera produced, neutralized the homologous pprv but not the heterologous rinderpest kabette "o" virus. the antisera gave strong precipitin lines with purified pprv antigens and were used to detect pprv and rinderpest virus antigens from ante-mortem secretions and post-mortem tissue homogenates from ppr and rinderpest vi ... | 1990 | 2396483 |
| characterisation of the european seal morbillivirus. | the elisa test originally developed for the detection of serum antibodies to rinderpest virus has been shown to detect cross-reacting antibodies in sera of diseased common and grey seals. analysis of sera collected from various seal populations is in progress to establish the correlation between different morbillivirus neutralisation tests, elisa tests and the disease status of the animals. rna purified from post-mortem tissues removed from diseased seals has been analysed by hybridisation with ... | 1990 | 2402877 |
| microneutralisation systems for use with different strains of peste des petits ruminants virus and rinderpest virus. | comparative studies were made to determine the most suitable microtitration system for assaying strains of peste des petits ruminants virus (pprv) and rinderpest virus (rv). infectivity titres did not differ significantly when assayed in either calf kidney, sheep kidney or vero cells. however, cytopathic effects were much easier to detect in the latter making them the cell of choice. addition of small amounts of virus to preformed cell monolayers in microplates with the subsequent addition of ma ... | 1985 | 2411037 |
| [attenuation of a strain of rinderpest virus: potential homologous live vaccine]. | peste des petits ruminants (ppr) is a highly contagious disease of small ruminants frequently associated with severe mortality in these hosts. in countries where it occurs, ppr represents an important constraint to the improved productivity of sheep and goats. until now the only way to combat this plague has been the use of heterologous rinderpest vaccine; all attempts to develop a homologous vaccine have ended in failure. the present communication describes the attenuation of the nigerian strai ... | 1989 | 2485537 |
| etiologic studies on the association of goat pox with peste des petits ruminants (ppr) disease in nigeria. | | 1989 | 2552956 |
| peste des petits ruminants of sheep in india. | | 1989 | 2609485 |
| management of clinical cases of peste des petits ruminants (ppr) disease in goats. | clinical cases of peste des petits ruminants (ppr) disease in goats were treated symptomatically. broad spectrum antibiotics, intestinal sedatives and fluid therapy were used for the treatment of pneumonia, diarrhoea and the restoration of the body fluid ionic balance. good feeding and nursing in warm, draught-free pens are necessary. lemon fruit and citrus aurantium proved to be effective for the treatment of the orf-like labial scabs. this treatment raised the survival rate of goats by 13.3%. | 1989 | 2619704 |
| dot enzyme immunoassay for visual detection of peste-des-petits-ruminants virus antigen from infected caprine tissues. | an enzyme-linked immunosorbent microassay using nitrocellulose paper as the solid-phase support was developed for the detection of peste-des-petits-ruminants virus antigens in infected caprine tissue homogenates. dots of tissue homogenates were applied to nitrocellulose papers, and any unreacted sites were blocked with 5% skim milk powder in triethanolamine-buffered saline. after incubation of the papers in tissue culture supernatant monoclonal antibody against the peste-des-petits-ruminants vir ... | 1989 | 2674200 |
| differentiation of rinderpest and peste des petits ruminants viruses using specific cdna clones. | the morbilliviruses which infect ruminants, rinderpest (rpv) and peste des petits ruminants (pprv), are difficult to distinguish serologically. they can be distinguished by differential neutralisation tests and by the migration of the major virus structural protein, the nucleocapsid protein, on polyacrylamide gels. both these methods are time consuming and require the isolation of live virus for identification; they are not suitable for analysis of material directly from post-mortem specimens. w ... | 1989 | 2723018 |
| duration of maternal immunity to peste des petits ruminants. | | 1989 | 2773199 |
| correlation of humoral immune response with clinical presentation, pulmonary lesions and mortality patterns of goats experimentally infected with peste des petits ruminants virus. | the patterns of humoral immune response, measured by enzyme-linked immunosorbent assay and the development of clinical signs, pulmonary lesions and mortality patterns were studied in goats experimentally infected with peste des petits ruminants virus (pprv) or kata virus. it was possible to classify the animals into high and low responders according to the pattern of humoral immune response. the high responders had a prolonged, chronic infection characterized by a giant cell pneumonia which was ... | 1989 | 2776471 |
| fluid, electrolyte and haematological changes in experimental peste des petits ruminants virus infection in west african dwarf goats. | the changes in plasma volume, blood volume, erythrocyte indices, leucocyte indices and serum biochemical values during experimental pestes des petits ruminants (ppr) virus infection of west african dwarf goats (fouta djallon) were investigated. there was a progressive decline of the plasma volume and serum sodium and potassium values in all the infected goats as from day 5 post-infection and this became quite marked between days 10 and 23 post-infection. the fall was severest in those animals wh ... | 1989 | 2791649 |
| disease and mortality in small ruminants in the north west province of cameroon. | mortality rates and the prevalence of disease were assessed in 115 flocks of traditionally managed sheep and goats in two divisions of the north west province of cameroon by means of a questionnaire to the owners. the mortality rate was significantly higher in sheep than in goats and also higher in young stock than in adults. tethering the animals during the day resulted in significantly lower mortality in both adult and young sheep and also in kids. disease problems of small ruminants, identifi ... | 1989 | 2799946 |
| peste des petits ruminants and cost effectiveness of its prevention in niger. | | 1988 | 3148274 |
| experimental peste des petits ruminants (goat plague) in goats and sheep. | in order to study the pathomorphology and immunohistochemistry of peste des petits ruminants, four goats and two sheep were inoculated intranasally with the malig-yemen strain of peste des petits ruminants virus. the animals developed fever, nasal discharge, oral erosions, cough and diarrhea. one goat and one sheep died and one moribund goat was killed. three animals survived the infection. at necropsy, erosive stomatitis, pneumonia and gastroenteritis were found. histopathologically the pneumon ... | 1988 | 3280108 |
| the molecular biology of the morbillivirus (measles) group. | the morbilliviruses are a closely related group of important human and animal pathogens. the best known members of the group are measles virus in man and canine distemper virus in dogs. the group also includes two other serious animal diseases, rinderpest or cattle plague and peste des petits ruminants in sheep and goats. the latter viruses are of great economic importance in africa, asia and the middle east. persistence of these viruses in some form is a possible mechanism whereby life-long imm ... | 1987 | 3332767 |
| an outbreak of peste des petits ruminants in a zoological collection. | peste des petits ruminants virus was suspected to be the cause of a disease outbreak in a zoological collection at al ain in the arabian gulf. clinically the outbreak affected gazelles (gazellinae), ibex and sheep (caprinae) and gemsbok (hippotraginae); subclinical involvement of nilgai (tragelaphinae) was suspected. a morbillivirus was isolated and using monoclonal antibodies and biological tests in cattle, sheep and goats the virus of peste des petits ruminants was identified. | 1987 | 3424615 |
| application of a precipitinogen inhibition test in the detection of antibody to peste des petits ruminants virus. | | 1987 | 3444960 |
| comparison of proteins induced in cells infected with rinderpest and peste des petits ruminants viruses. | the two morbilliviruses rinderpest virus (rpv) and peste des petits ruminants virus (pprv) are closely related and cause severe disease in large and small ruminants, respectively. they show distinct epidemiological patterns and are distinguishable by reciprocal cross-neutralization tests. we have analysed the proteins induced by these viruses in infected cells and have shown that they can be distinguishable by a very marked difference in the apparent mol. wt. of the nucleocapsid (n) protein. the ... | 1987 | 3598564 |
| clinical and epidemiological features of peste des petits ruminants in sokoto red goats. | | 1986 | 3659476 |
| haematological changes in natural and experimental peste des petits ruminants virus infection in goats. | | 1985 | 3837920 |
| the differential growth of virulent and avirulent strains of rinderpest virus in bovine lymphocytes and macrophages. | rinderpest virus (rv) grew readily in cultures of purified bovine peripheral blood lymphocytes and udder macrophages. the growth of three strains of rv was compared and there appeared to be a relationship between increasing virulence and increased ability to infect lymphocytes and macrophages. the proportion of infected cells as determined by the presence of virus antigens was a better indicator of affinity between a strain and cell type than production of new infectious virus. rv grew better in ... | 1985 | 3873515 |
| comparison of messenger rnas induced in cells infected with each member of the morbillivirus group. | virus-specific mrnas radiolabelled with [32p]orthophosphate in the presence of actinomycin d were extracted from the cytoplasm of vero cells infected with each of the known morbilliviruses: measles virus, canine distemper virus, rinderpest virus, and peste des petits ruminants virus. when analysed on denaturing agarose-formaldehyde gels the major rna species from all viruses in the group were identical, except for canine distemper virus where one of the virus-specific mrnas (mrna 5), which proba ... | 1985 | 4013082 |
| hyperimmune serum in the control of peste des petits ruminants. | the value of administration of hyperimmune serum in the control of peste des petits ruminants was investigated in goats at different stages of the disease. a group of the goats was given hyperimmune serum intravenously at the fever stage of temperature of 40.5 degrees c or above; another group showing no elevation of temperature but with other clinical signs of the disease were also given hyperimmune serum. results indicated that hyperimmune serum was very effective in reversing the process of t ... | 1985 | 4024266 |
| the ultrastructure of peste des petits ruminants virus. | | 1985 | 4050210 |
| village production of west african dwarf goats and sheep in nigeria. | results from a 41 month study of west african dwarf goats and sheep under village conditions in south-west nigeria are reported. even at a very low level of management these trypanosomiasis-tolerant animals produced 2.01 kids or 1.51 lambs per dam per year. mortality of young particularly kids and low growth rates limit production. of these mortality is probably the first constraint to increased productivity and profitability. control of peste des petits ruminants appears to significantly reduce ... | 1985 | 4060235 |
| outbreaks of peste des petits ruminants in village goat flocks in nigeria. | peste des petits ruminants (ppr) is a major disease constraint of goat production in nigeria. investigation of three outbreaks in village goat populations in south-west nigeria showed overall attack rates of 42.4%, 13.7% and 37.1% and case fatality rates of 86.9%, 41% and 63.9% respectively. statistically significant differences were observed between attack rates in different age groups in each of the outbreaks. based on the mortalities suffered the estimated average loss per goat in each of the ... | 1985 | 4089968 |
| the histological relationship between "peste des petits ruminants" and kata in west africa. | | 1970 | 4323414 |
| a diseases of sokoto goats resembling "peste des petits ruminants". | | 1972 | 4366855 |
| a comparative study of peste des petits ruminants and kata in west african dwarf goats. | | 1971 | 5006087 |
| isolation of peste des petits ruminants virus from the sudan. | based on clinical signs, the presence of a rinderpest related antigen and the ability of rinderpest immune serum to prevent virus isolation, rinderpest was diagnosed in two outbreaks in goats in central sudan during 1971 and 1972. two viruses isolated from these goats have been re-examined both serologically and by the inoculation of experimental cattle, sheep and goats. each is now considered to represent the virus of peste des petits ruminants, thereby extending the geographical range of this ... | 1984 | 6200906 |
| some virus diseases of domestic animals in the sultanate of oman. | little is known of the occurrence of animal virus diseases in the sultanate of oman. this paper reports the results of a countrywide survey carried out in 1978 to establish the prevalence of some important viral pathogens of domestic animals with the dual purpose of providing baselines for future investigations and guidelines for those entrusted with disease control. foot-and-mouth disease virus type o, previously identified in oman in 1976, was isolated from clinically affected animals. in addi ... | 1980 | 6251586 |
| serological studies with peste des petits ruminants and rinderpest viruses in nigeria. | one hundred and ninety-five goat and 67 sheep sera collected from various parts of southern nigeria were screened for neutralising antibodies to both the peste des petits ruminants (ppr) and rinderpest viruses. neutralising antibodies against both viruses were found in the sheep and goat sera examined. parallel titration of samples which neutralised both viruses indicated a primary infection with the ppr virus (pprv). however, some samples which failed to neutralise pprv neutralised the rinderpe ... | 1984 | 6485096 |
| serum-virus simultaneous method of immunisation against peste des petits ruminants. | peste des petits ruminants (ppr) hyperimmune serum was prepared in cattle and used to protect goats against ppr. the serum was well tolerated by goats and 8 ml of serum was found to protect goats against 4 ml of pooled virulent ppr virus. a durable active immunity was conferred on goats when serum and virulent ppr virus were given simultaneously. passive immunity lasted for 15 days. | 1984 | 6485097 |
| rapid diagnosis of peste des petits ruminants (ppr) infection, application of immunoelectroosmophoresis (ieop) technique. | | 1984 | 6494531 |
| experimental infection of goats with mycoplasma capri and "peste des petits ruminants" virus. | | 1984 | 6494532 |
| the detection of peste des petits ruminants (ppr) virus antigen by agar gel precipitation test and counter-immunoelectrophoresis. | the detectability of peste des petits ruminants (ppr) viral antigen in both ante-mortem secretions and necropsy samples from experimentally infected goats was investigated by both the agar gel precipitation test (agpt) and counter-immunoelectrophoresis (cie). viral antigen was detected from 42.6% of the samples tested by the agpt and 80.3% by cie. the detection of viral antigen in a high proportion of the ocular and nasal secretions as well as the faeces and buccal scrapings, particularly from t ... | 1984 | 6512258 |
| application of countercurrent immuno-electro-osmo-phoresis to the serology of peste des petits ruminants. | | 1984 | 6536999 |
| peste des petits ruminants (ppr) in goats in nigeria: clinical, microbiological and pathological features. | | 1983 | 6670423 |
| paramyxoviruses of the morbilli group in the wild hedgehog erinaceus europeus. | dead and sick hedgehogs (erinaceus europeus) were examined, together with apparently healthy individuals, and paramyxo virus of the morbilli group was isolated. one animal's symptoms were similar to those caused by canine distemper and the virus isolate from faecal suspensions from this animal were antigenically related in various degrees to measles, canine distemper, rinderpest and pprv viruses. isolates from normal hedgehogs were found to belong to the same group. the variability and host spec ... | 1981 | 7013778 |
| precipitating antibody in sera of goats naturally affected with peste des petits ruminants. | | 1982 | 7101469 |
| the nucleotide sequence of the fusion protein gene of the peste des petits ruminants virus: the long untranslated region in the 5'-end of the f-protein gene of morbilliviruses seems to be specific to each virus. | cdna corresponding to the fusion protein (f) gene of the vaccine strain of peste des petits ruminants virus (pprv) was cloned and sequenced. the gene was 2321 nucleotides long excluding the poly(a) tail. as with other morbilliviruses, it had a long g/c rich stretch of about 525 nucleotides. there was no start codon before position 489 in the nucleotide sequence. from the 489th nucleotide to the 549th nucleotide, there were 4 atg codons, two of which were in frame. the fourth atg codon was in the ... | 1995 | 7483819 |
| differential immunohistochemical staining of peste des petits ruminants and rinderpest antigens in formalin-fixed, paraffin-embedded tissues using monoclonal and polyclonal antibodies. | | 1994 | 7516718 |
| differentiation of peste des petits ruminants and rinderpest viruses by neutralisation indices using hyperimmune rinderpest antiserum. | six field isolates believed to be rinderpest viruses and 2 known strains of peste des petits ruminants (ppr) viruses were titrated in the presence of normal rabbit serum and with hyperimmune rinderpest antiserum prepared in rabbits. the known ppr viruses had indices less than 10 whereas 4 of the suspect field isolates had indices greater than a hundred. two suspect field isolates had indices less than 20; both were collected from small ruminant wild life and are probably ppr viruses. | 1995 | 7652944 |
| development of a competitive elisa for detecting antibodies to the peste des petits ruminants virus using a recombinant nucleoprotein. | a competitive elisa based on the reaction between a monoclonal antibody (mab) and a recombinant nucleoprotein of the peste des petits ruminants virus (pprv) was developed. this protein was obtained in large quantities from insect cells infected with a ppr nucleoprotein recombinant baculovirus (n-b). the competitive elisa was compared with the virus neutralisation test (vnt) for detecting specific antibodies to pprv in sheep and goats. the time consuming vnt is the only prescribed test that is ca ... | 1995 | 7709061 |
| cloning and expression of the nucleoprotein of peste des petits ruminants virus in baculovirus for use in serological diagnosis. | peste des petits ruminants (ppr) is a viral disease of goats and sheep characterized by erosive stomatitis, enteritis, and pneumonia. the virus is a member of the family paramyxoviridae and the genus morbillivirus. the disease has high morbidity and mortality rates and has a substantial economic impact in developing countries. we have cloned and sequenced the cdna of the nucleocapsid (n) gene of the nigeria 75/1 strain of ppr virus (pprv). a comparison of its nucleotide and deduced amino acid se ... | 1995 | 7747450 |
| peste des petits ruminants antibodies in east africa. | | 1995 | 7754596 |
| protection of goats against peste des petits ruminants with recombinant capripoxviruses expressing the fusion and haemagglutinin protein genes of rinderpest virus. | goats were protected against a lethal challenge of peste des petits ruminants (ppr) virus following vaccination with a recombinant capripoxvirus containing either the fusion (f) gene of rinderpest virus or the haemagglutinin (h) gene of rinderpest virus. the h gene recombinant produced high titres of neutralizing antibody to rinderpest virus in the vaccinated goats, whereas the f gene recombinant failed to stimulate detectable levels of neutralizing antibody. a similar response to the two recomb ... | 1995 | 7762275 |
| peste des petits ruminants in ethiopian goats. | an outbreak of disease characterised by fever, ocular and nasal discharge, coughing and sneezing, oral necrosis, diarrhoea, enteritis and pneumonia in goats was shown by the use of specific cdna probes to have been peste des petits ruminants, confirmed for the first time in ethiopia. both morbidity and mortality rates were high in goats but sheep were not affected. | 1994 | 7941031 |
| applications of recombinant vaccinia virus for veterinary vaccines. | | 1994 | 7958475 |
| rapid differential diagnosis of rinderpest and peste des petits ruminants using an immunocapture elisa. | an immunocapture elisa for the diagnosis of rinderpest and peste des petits ruminants is described. monoclonal antibodies directed against non-overlapping antigenic domains on the nucleocapsid (n) were used to detect the virus n protein in supernatants from infected cells and in field specimens. the assay, which is very sensitive, can be performed in one hour on pre-coated plates. there was no cross reaction between the two viruses in the test and the n protein could be detected in infected cell ... | 1994 | 8009788 |
| genetically engineered vaccines for animal viral diseases. | | 1994 | 8050940 |
| comparison of monoclonal antibody-based sandwich enzyme-linked immunosorbent assay and virus isolation for detection of peste des petits ruminants virus in goat tissues and secretions. | a monoclonal antibody-based sandwich enzyme-linked immunosorbent assay (s-elisa) was developed for specific detection of peste des petits ruminants virus. compared with virus isolation in vero cell cultures using 89 paired tissue and secretion samples from six experimentally infected goats, s-elisa was significantly more sensitive (71.9% versus 65.2%; p < 0.05). the s-elisa is a suitable alternative to virus isolation. | 1994 | 8051266 |
| cloning of the nucleocapsid protein gene of peste-des-petits-ruminants virus: relationship to other morbilliviruses. | two independent cdna clones, identified as representing the mrna of the nucleocapsid protein gene of peste-des-petits-ruminants virus, were sequenced. the longest insert was 1662 nucleotides, not counting the poly(a) tail, and it was estimated that about 21 nucleotides were missing from the complete gene sequence. the sequence contained one long open reading frame encoding a protein of 525 amino acids with a predicted relative molecular mass of 58,008. comparisons of the nucleic acid and protein ... | 1994 | 8113734 |
| the detection of antibodies against peste des petits ruminants virus in cattle, sheep and goats and the possible implications to rinderpest control programmes. | monoclonal antibody-based competitive elisa (c-elisa) have been used for the specific measurement of antibodies to both rinderpest and peste des petits ruminants (ppr) viruses in cattle, sheep and goats. examination of serum samples from sheep and goats in gambia, before and after vaccination with rinderpest vaccine, suggested that antibodies to ppr virus could prevent an immune response to the rinderpest vaccine. cattle sera from nigeria and ghana showed a high prevalence of antibody against pp ... | 1994 | 8119361 |
| cloning and sequence analysis of the matrix (m) protein gene of rinderpest virus and evidence for another bovine morbillivirus. | we have cloned and sequenced the entire m gene of the vaccine strain of rinderpest virus and that of the virulent kabete "o" strain from which it was derived. the sequences of these two genes are essentially identical (99% at the nucleotide level), but were very different from a previously published kabete o m gene sequence (m. limo and t. yilma, 1990, virology 175, 323-327). inspection of the nucleotide and deduced amino acid sequences of known morbillivirus m genes showed that the earlier sequ ... | 1994 | 8128616 |
| neutralizing antibodies to phocine distemper virus in atlantic walruses (odobenus rosmarus rosmarus) from arctic canada. | the first evidence of phocine distemper virus (pdv) infection in atlantic walruses (odobenus rosmarus rosmarus) from nottingham island, northwest territories, canada, is reported. blood samples were collected from three male walruses killed by inuit hunters in the fall of 1990. differential virus neutralization test for each animal yielded higher titers against pdv than against other members of the morbillivirus genus including canine distemper, peste des petits ruminants, rinderpest and measles ... | 1994 | 8151831 |
| protection of goats against peste des petits ruminants with a vaccinia virus double recombinant expressing the f and h genes of rinderpest virus. | peste des petits ruminants (ppr) is a viral disease of goats and sheep characterized by necrotizing and erosive stomatitis, enteritis and pneumonia. the causative agent, pprv, is a member of the family paramyxoviridae and the genus morbillivirus. other members of the genus include rinderpest (rpv), measles, canine distemper and phocid distemper viruses. ppr has a very high rate of morbidity and mortality, and effective control of this disease is of economic importance in africa, asia and the mid ... | 1993 | 8212844 |
| rinderpest and peste des petits ruminants-like disease in the al-ain region of the united arab emirates. | the author demonstrates that rinderpest prevailed among the cattle population in the al-ain region of the united arab emirates from 1987 to 1989. a total of twenty-four outbreaks of rinderpest were recorded during the study period. similarly, evidence of the peste des petits ruminants (ppr) or a ppr-like disease was regularly encountered in small ruminants in a total of forty-one outbreaks. | 1993 | 8219335 |
| cloning and expression of the nucleocapsid gene of virulent kabete o strain of rinderpest virus in baculovirus: use in differential diagnosis between vaccinated and infected animals. | rinderpest (rp) is a viral disease of ruminants with > 95% morbidity and mortality. we have cloned the cdna of the nucleocapsid (n) gene of the virulent kabete o strain of rinderpest virus (rpvk) and compared its nucleotide and deduced amino acid sequences with those of the n genes of the lapinized strain of rinderpest virus (rpvl), measles virus (mv), and canine distemper virus (cdv). the gene has an open reading frame of 1575 nucleotides and encodes a protein of 525 amino acids with a molecula ... | 1994 | 8259649 |
| biological properties of phocine distemper virus and canine distemper virus. | morbilliviruses constitute a major threat to the health of animal and man. to date the morbillivirus genus in the paramyxoviridae family comprises five established members, namely canine distemper virus (cdv), phocine distemper virus (pdv), measles virus (mv), rinderpest virus (rpv), and peste-des-petits-ruminants virus (pprv). in addition, morbillivirus candidates infecting aquatic mammals were recently discovered. the present review on the biology of morbilliviruses focuses on knowledge gained ... | 1993 | 8268007 |
| morbillivirus infections in aquatic mammals. | infections with morbilliviruses have caused heavy losses among different populations of aquatic mammals during the last 5 years. two different morbilliviruses were isolated from disease outbreaks among seals in europe and siberia: phocid distemper virus-1 (pdv-1) and phocid distemper virus-2 (pdv-2) respectively. pdv-1 was characterized as a newly identified morbillivirus, most related to canine distemper virus (cdv), whereas pdv-2 most probably is a strain of cdv. morbilliviruses were also isol ... | 1993 | 8343804 |
| field diagnostic kits: a solution for developing countries? | an exact assessment of the animal health situation in a country is an essential element in formulating eradication and control programmes, and in regulating international trade in animals and animal products from that country. due to a lack of human and technical resources, veterinary services in developing countries often lack precise knowledge on disease occurrence. since the collection and transmission of reliable information on animal diseases in developing countries are major concerns of th ... | 1993 | 8400385 |
| the use of thermostable vero cell-adapted rinderpest vaccine as a heterologous vaccine against peste des petits ruminants. | the thermostable vero cell-adapted rinderpest vaccine was evaluated in terms of immunogenicity as a heterologous vaccine against peste des petits ruminants. a titration to establish the minimum immunising dose was performed in american mixed breed goats by vaccinating test subjects with dilutions of vero cell-adapted rinderpest vaccine and then challenging 26 days later with virulent peste des petits ruminants virus. all animals were followed for virus neutralising antibodies against both rinder ... | 1993 | 8460262 |
| monoclonal antibody-based blocking enzyme-linked immunosorbent assay for specific detection and titration of peste-des-petits-ruminants virus antibody in caprine and ovine sera. | a blocking enzyme-linked immunosorbent assay (b-elisa), using two neutralizing monoclonal antibodies (mabs), was established and compared with the virus neutralization test (vnt) for detecting specific peste-des-petits-ruminants virus (pprv) antibody in caprine and ovine sera. this technique was developed because vnt, the only available specific serological test for pprv and the cross-reactive rinderpest virus (rpv), is time-consuming and unaffordable for most laboratories in regions where both ... | 1993 | 8501207 |
| prevalence of morbilliviruses among pinniped and cetacean species. | since 1987, morbillivirus infections have caused serious disease outbreaks with high mortality among aquatic mammals. baikal seals (phoca sibirica) in siberia were involved in an outbreak caused by a virus closely related to canine distemper virus (cdv) in 1987. harbour seals (phoca vitulina) and grey seals (halichoerus grypus) in north-western europe were struck by a newly recognised morbillivirus of seals (pdv1). a serological survey has indicated that these morbillivirus infections frequently ... | 1993 | 8518442 |
| protection of goats against rinderpest by vaccination with attenuated peste des petits ruminants virus. | the ability of the attenuated peste des petits ruminants vaccine virus to protect small ruminants against virulent rinderpest virus was investigated. out of four susceptible goats that were infected with the highly virulent saudi strain of rinderpest virus by intranasal ioculation, three developed mild clinical signs of disease and infected susceptible in-contact goats and cattle with rinderpest virus. however, four goats which had been vaccinated with the attenuated peste des petits ruminants v ... | 1995 | 8525096 |
| morbilliviruses and morbillivirus diseases of marine mammals. | in recent years, serious disease outbreaks among seals and dolphins were attributed to infection with established or newly recognized morbilliviruses. the first identification of a morbillivirus as causative agent of mass mortality among marine mammals was in 1988, when the previously unrecognized phocine distemper virus (pdv) caused the death of 20,000 harbor seals (phoca vitulina) in northwestern europe. a similar epizootic among baikal seals (phoca sibirica) in siberia in 1987 was later attri ... | 1995 | 8548190 |
| morbillivirus infection in cetaceans of the western atlantic. | we report serologic evidence of morbillivirus infection in eleven of fifteen species of odontocete cetaceans from the western atlantic since 1986. blood samples were obtained both from free-ranging and stranded animals. virus neutralizing titers were higher against porpoise and dolphin morbilliviruses than against peste des petits ruminants virus, phocine distemper virus or canine distemper virus (cdv). serum from five species, tested in a heterologous immunoprecipitation assay using radiolabell ... | 1995 | 8588318 |