| concentric lamellated psammoma-like bodies in the third ventricle of the european mole rat (spalax leucodon, nordmann 1840). | concentric lamellated bodies are described in the third ventricle of the european mole rat. these bodies show most staining characteristics of true psammoma bodies found in humans but were never calcified in the mole rat. | 1978 | 80912 |
| different populations of pinealocytes in the pineal gland of the mole-rat (spalax leucodon, nordmann). | | 1979 | 549081 |
| coccidia (protozoa: eimeridae) of the herbivorous mole-rat, spalax leucodon nordmann. | a survey of 96 herbivorous mole-rats, spalax leucodon nordmann, in lalahan district of ankara, turkey, revealed the presence of 6 new species of coccidia. the species found, the shape and average length-width dimensions (in micrometers) of their oocysts, and the numbers of animals from which they were isolated were as follow: eimeria lalahanensis sp. n., subspherical to ellipsoidal (20.3 x 12.5), from 10; eimeria tuzdili sp. n., spherical to subspherical with radially striated oocyst wall, (20.5 ... | 1977 | 881650 |
| limited polymorphism of both classes of mhc genes in four different species of the balkan mole rat. | we analyzed the restriction fragment length polymorphism of class i and class ii mhc genes in dna from 20 individuals belonging to the four different species of the complex of species of balkan mole rats spalax leucodon captured at four different localities in yugoslavia. all populations were tested with four restriction enzymes and one conserved mouse probe for each of the two classes of mhc genes. the probes employed detect either limited polymorphism of class i genes or lack of polymorphic ba ... | 1988 | 2899548 |
| immunological responses in the mole rat (spalax leucodon). ii. serum proteins of nonimmunized mole rats. | | 1973 | 4201053 |
| immunological responses in the mole rat (spalax leucodon). i. antibody production, delayed hypersensitivity and lymphatic tissue. | | 1973 | 4269227 |
| ultrastructural study of the optic nerve in blind mole-rats (spalacidae, spalax). | the optic nerve in two species of subterranean mole-rats (spalacidae) has been examined at the ultrastructural level. the axial length of the eye and the diameter of the optic nerve are 1.9 mm and 52.5 microns in spalax leucodon, and 0.7 mm and 80.8 microns in spalax ehrenbergi, respectively. an anti-glial fibrillary acidic protein postembedding procedure was used to distinguish glial cell processes from axons. in both species, the optic nerve is composed exclusively of unmyelinated axons and a ... | 1995 | 7786846 |
| chromosomal speciation and adaptive radiation of mole rats in asia minor correlated with increased ecological stress. | the evolutionary forces causing chromosomal speciation and adaptation are still enigmatic. here we tested the israel evolutionary model of positive association of diploid chromosome number (2n) and genetic diversity with aridity stress in subterranean mole rats, on a 30-times-larger scale in asia minor. we analyzed both karyotype and allozyme diversity across turkey, based on 37 allozymic loci in 20 localities of the spalax leucodon and 4 localities of the spalax ehrenbergi superspecies. we foun ... | 1994 | 8058774 |
| the primary structure of pancreatic ribonuclease from mole rat superspecies spalax leucodon. | the primary structure of pancreatic ribonuclease of the superspecies spalax leucodon has been determined. only one difference with the previously determined sequence of the superspecies spalax ehrenbergi was detected; the proline residue at position 42 has been replaced by alanine. proline-42 is a well-conserved residue in mammalian pancreatic ribonucleases; the only other species with alanine at this position is the three-toed sloth. as the muridae and the spalacidae diverged 20-40 million year ... | 1993 | 8136926 |
| variations in ribosomal dna and mitochondrial dna among chromosomal species of subterranean mole rats. | restriction site variations in nuclear ribosomal dna (rdna) spacers and mitochondrial dna (mtdna) were examined in several populations of mole rats with variable numbers of chromosomes, which represented the two superspecies spalax leucodon (2n = 38, 54, or 62) and spalax ehrenbergi (2n = 52, 54, 58, or 60). sequence divergence of rdna spacers between the members of the superspecies was approximately 8%, while the variation within each superspecies was 4% on average. the intrasuperspecies differ ... | 1996 | 8583910 |
| morphological investigations on the circulus arteriosus cerebri in mole-rats (spalax leucodon). | the aim of the present study is to investigate the circulus arteriosus cerebri in mole-rats (spalax leucodon). six adult mole-rats were used for this purpose. coloured latex was injected into the left ventriculus of the hearts of all the animals. after careful dissection, the circulus arteriosus cerebri (the circle of willis) was investigated. the cerebrum and the cerebellum were supplied by the internal carotid- and the basilar arteries respectively forming the circulus arteriosus cerebri in mo ... | 2008 | 18215205 |
| discrimination of 2n = 60 spalax leucodon cytotypes (spalacidae, rodentia) in turkey by means of classical and molecular cytogenetic techniques. | comparative studies among seven populations of 2n = 60 s. leucodon employing classic cytogenetics (g- bands, c-bands, agnor-staining), fluorochrome staining, and fluorescence in situ hybridization of telomeric and rdna probes are reported here for the first time. the studied specimens were assigned to two cytotypes: 2n = 60w and 2n = 60r. the basic karyotype of both cytotypes consisted of eight pairs of subtelocentric and 21 pairs of acrocentric autosomes, subtelocentric x and acrocentric y chro ... | 2008 | 19096209 |
| macro-anatomical and karyological features of two blind mole rat subspecies (rodentia: spalacidae) from turkey. | the morphometric and karyological analyses of 52 specimens belonging to the two subspecies of nannospalax leucodon were examined from 14 localities in turkey. five karyotypic forms were recorded (2n = 60, the total numbers of chromosomal arms (nf) = 74, the numbers of autosomal arms (nfa) = 70; 2n = 60, nf = 76, nfa = 72; 2n = 60, nf = 82, nfa = 78; 2n = 56, nf = 72, nfa = 68; 2n = 38, nf = 74, nfa = 70). the morphological features of two subspecies were studied using both numerical taxonomy and ... | 2009 | 19183350 |
| existence of serotonin and neuropeptides-immunoreactive endocrine cells in the small and large intestines of the mole-rats (spalax leucodon). | the present study was conducted to clarify the regional distribution and relative frequency of endocrine cells secreting serotonin, substance p (sp), cholecystokinin-8 (cck-8), vasoactive intestinal polypeptide (vip) and neurotensin in the small and large intestine of the mole-rats (spalax leucodon), by specific immunohistochemical methods. in the small and large intestine of mole-rats (spalax leucodon), serotonin, sp and vip were identified with various frequencies, but cck-8 and neurotensin we ... | 2012 | 22608308 |
| exceptional chromosomal evolution and cryptic speciation of blind mole rats nannospalax leucodon (spalacinae, rodentia) from south-eastern europe. | mole rats are exclusively subterranean and highly specialized rodents. their long lifespans, remarkable anti-cancer mechanisms, and various distinctive adaptive features make them a useful research model. moreover, opposing convergence of morphological traits, they have developed extremely high karyotype variability. thus, 74 chromosomal forms have been described so far and new ones are being revealed continuously. these evolved during the process of rapid radiation and occur in different biogeo ... | 2017 | 29068425 |
| immunohistochemical localization of irisin in mole rats (spalax leucodon). | irisin was first identified in skeletal muscle cells. it is an exercise protein that is secreted into the circulation; it causes conversion of white adipose tissue to brown adipose tissue. we investigated irisin immunoreactivity in mole rat (spalax leucodon) tissues. we examined cerebellum, pituitary, heart, liver, pancreas, spleen, uterus, kidney and striated muscle in female adult mole rats. tissues were processed, embedded in paraffin, sectioned at 5 μm and stained immunohistochemically for i ... | 2017 | 28409694 |
| immunohistochemical localization of androgen receptors in female mole rat (spalax leucodon) tissues. | androgens exert their effects through androgen receptors (ar) in tissues. we investigated the distribution of ar in female mole rat tissues. tissues were excised, fixed with 10% formalin and embedded in paraffin. sections were stained after microwave antigen retrieval for immunohistochemistry. immunostaining of ar immunostaining was detected in the nucleus or cytoplasm of the cells in the cerebral cortex, cerebellum, anterior pituitary, lung, liver, uterus and skin. granulosa and some thecal cel ... | 2016 | 27676207 |
| the effects of ultraviolet c radiation on the ultrastructure of the liver cells of mole rats. | the aim of this study was to elucidate the ultrastructural changes in the liver cells of mole rats (spalax leucodon) exposed to ultraviolet radiation (uvr). thirteen mole rats used in this study were caught from nature. they were divided into four groups. the first group was separated as a control and was not given any radiation. the rest were exposed to ultraviolet c (uvc) radiation for 7, 14, and 21 days. the electron microscopic examinations revealed that significant ultrastructural changes o ... | 2016 | 26512906 |
| comparison of the chromosome banding pattern in the 2n = 56 cytotypes of nannospalax leucodon and n. xanthodon from turkey. | we present the karyotype characteristics of five cytotypes of mole rats (nannospalax) with 56 chromosomes revealed by the c-banding and agnor staining analyses. we attempt to investigate if the specific distinction between the populations from thrace (n. leucodon) and anatolia (n. xanthodon) is reflected also in their karyotypic differentiation. the specimens from each of the five populations studied revealed a distinct karyotype which was different from those found in other populations. the fun ... | 2014 | 24587706 |
| macroscopic anatomy of the lower respiratory system in mole rats (spalax leucodon). | the morphologic and morphometric features of the lower respiratory system in mole rats were examined. it was seen that the low respiratory system of this species leading a special life under highly hypoxic/hypercapnic conditions underground is structurally similar to other mammals living on land in terms of the parts examined; trachea was formed by 29.5 ± 4 oval-formed cartilaginous tracheals arranged backwards and became gradually more stenotic diameter from cranial to the caudal of the neck. t ... | 2014 | 24450964 |
| european rodent on the edge: status and distribution of the vojvodina blind mole rat. | recent research of blind mole rats of the species complex nannospalax (superspecies leucodon) identified a small and fragmented population of these rodents on both sides of the hungarian-serbian border. cytogenetic investigations proved that this population karyologically identical with the vojvodina blind mole rat described earlier as nannospalax (leucodon) montanosyrmiensis. based on cytochrome b gene sequences obtained from three specimens originating from separate locations, these blind mole ... | 2013 | 23459680 |
| [ultrastructural analysis of the optic nerve in microphthalmic rodents (spalax leucodon)]. | the optic nerve of a microphthalmic subterranean rodent, spalax leucodon, has been examined at the ultrastructural level. the analysis of the optic nerve reveals only 1,790 unmyelinated axons. the axon diameter varies from 0.05 to 2.3 microns, with a mean of 0.55 micron. we suggest that these axons mainly belong to the w type ganglion cells. | 1993 | 8364764 |
| proetolytic enzymes of citellus citellus and spalax leucodon. | | 1966 | 5915977 |
| liver anatomy, intrahepatic vascular and biliary branching system of the mole rat (spalax leucodon). | there are many studies on the morphology of the liver and its blood vessels in experimental animals, but such studies are lacking in the mole rat (spalax leucodon). the aim of this paper was a detailed basic study on the topography, morphology, vascular and biliary branching systems of the liver in the mole rat. colored gelatine and mixture of colored lead oxide and linseed oil were injection contrast masses used to obtain vascular and biliary branching pattern in the liver. it was revealed that ... | 2020 | 33124033 |
| microbiome and longevity: high abundance of longevity-linked muribaculaceae in the gut of the long-living rodent spalax leucodon. | with a world population living longer as well as marked disparities in life expectancy, understanding the determinants of longevity is one of the priority research agendas in 21st century life sciences. to this end, the blind mole-rat (spalax leucodon), a subterranean mammalian, has emerged as an exceptional model organism due to its astonishing features such as remarkable longevity, hypoxia and hypercapnia tolerance, and cancer resistance. the microbiome has been found to be a vital parameter f ... | 2020 | 32907488 |
| descriptions of two new species and a new subspecies of the genus ctenophthalmus (insecta: siphonaptera: ctenophthalmidae) from turkey. | two new species and a new subspecies of fleas belonging to the genus ctenophthalmus kolenati (siphonaptera: ctenophthalmidae) were described from turkey. ctenophthalmus (spalacoctenophthalmus) beyzanurae n. sp. was collected from nannospalax leucodon nordmann (mammalia: rodentia) in tekirdağ province while ctenophthalmus (euctenophthalmus) kefelioglui n. sp. and ctenophthalmus (euctenophthalmus) teres anatolicus n. ssp. were collected from microtus guentheri (danford & alston) and apodemus urale ... | 2019 | 31245824 |
| blind mole rat (spalax leucodon) masseter muscle: structure, homology, diversification and nomenclature. | it is well known that rodents are defined by a unique masticatory apparatus. the present study describes the design and structure of the masseter muscle of the blind mole rat (spalax leucodon). the blind mole rat, which emer- ged 5.3-3.4 million years ago during the late pliocene period, is a subterranean, hypoxia-tolerant and cancer-resistant rodent. yet, despite these impressive cha- racteristics, no information exists on their masticatory musculature. | 2019 | 30371935 |