| annual variations in the plasma thyroxine level in microcebus murinus. | there is a great annual variation of plasma thyroxine (t4) in microcebus murinus. the averages range between 30 and 68 ng/ml from february to july, and fall to 6 ng/ml in november. long photoperiods seem to be the environmental factor responsible for the summer increase in plasma t4 as they are for testosterone. there is no apparent phase opposition with annual testosterone variation. | 1984 | 6468919 |
| evidence on primate phylogeny from epsilon-globin gene sequences and flanking regions. | phylogenetic relationships among various primate groups were examined based on sequences of epsilon-globin genes. epsilon-globin genes were sequenced from five species of strepsirhine primates. these sequences were aligned and compared with other known primate epsilon-globin sequences, including data from two additional strepsirhine species, one species of tarsier, 19 species of new world monkeys (representing all extant genera), and five species of catarrhines. in addition, a 2-kb segment upstr ... | 1995 | 7714911 |
| hematology of the lesser mouse lemur (microcebus murinus). a preliminary study. | some blood values of 86 lesser mouse lemurs (microcebus murinus) maintained in captivity are presented. these are comparable with those of other prosimians: pcv 51.7%, rbc 9.2 x 10(6)/mm3, mcv 57.5 micron3, wbc 12,900/mm3, lymphocytes 59.7%, neutrophils 30.7%, monocytes 4.8%, eosinophils 4.2%, basophils 0.6%. we noted no significant difference between the sexes except that the percentage of lymphocytes was slightly lower in the females (with a corresponding percentage of neutrophils slightly hig ... | 1983 | 6418625 |
| plasma testosterone-binding globulin-binding capacity in the male lesser mouse lemur (microcebus murinus): relationship to seasonal and social factors. | plasma testosterone-binding globulin (tebg)-binding capacity was determined by equilibrium dialysis in the lesser mouse lemur (microcebus murinus), a prosimian which exhibits a clear photoperiod-dependent sexual cycle. plasma tebg-binding capacity showed significant seasonal changes which were inversely correlated to those of plasma testosterone concentrations. the capacity of tebg was at its maximum (1.72 +/- 0.4 mumol/l) during the sexual rest period and decreased to 0.98 +/- 0.24 mumol/l duri ... | 1986 | 3734676 |
| [the occupation of space and interindividual relations of a nocturnal madagascan prosimian (microcebus murinus)]. | five male and four female grey lesser mouse lemurs, microcebus murinus, were trapped with sherman traps in the forestry reserve of ampijoroa, near majunga, n.w.-madagascar and equipped with individual radio-transmitters with a range of 220-300 m. these 9 individuals were then followed and observed (alternatively or simultaneously) for a total of 30 nights spread over a period of 6 weeks (26 september to 11 november 1985). in this dry deciduous forest zone, the subpopulation of 9 m. murinus obser ... | 1988 | 3240913 |
| developmental morphology of the solum nasi in the mouse lemur (microcebus murinus). | the solum nasi of microcebus murinus is characterized by the presence of a zona annularis, continuity between the anterior transverse lamina and the paraseptal cartilage, a continuous paraseptal cartilage, a palatine cartilage and a posterior transverse lamina. it lacks a fibula reuniens and possibly a cartilage of the nasopalatine duct as well as a palatine papillary cartilage. the morphology in m. murinus closely resembles that seen in tupaia and galago. this affinity results from the retentio ... | 1989 | 2600973 |
| [comparative anatomic studies of the tongue of pan troglodytes (blumenbach, 1799) and other primates. i. the chimpanzee tongue]. | this study was carried out on a comprehensive collection of tongues of pan troglodytes. material of tongues of tupaia glis, microcebus murinus, chirogaleus major, lemur catta, galago crassicaudatus, cebus apella, and macaca mulatta were used for comparison of the different stages of the development of the papilla foliata. the tongue of pan exhibits longitudinal growth correlated with the growth of length of the jaws and individual age. a typical foramen caecum as it occurs in man was gross anato ... | 1990 | 2242823 |
| vomeronasal activation by urine in the primate microcebus murinus: a 2 dg study. | the vomeronasal system (vns) seems to be functional in some primates and involved in the detection of urinary signals. anterograde tracing (wga-hrp) and evoked metabolic activity (2-dg method) were used in order to clarify the conditions under which the vns is activated in the prosimian mouse lemur. after wga-hrp deposition at one of the oral entries of the nasopalatine duct, reaction product was observed within the accessory bulb (aob). 2-dg experiments show that urine in the volatile phase sti ... | 1990 | 2226693 |
| localization and characterization of neuropeptide y in the brain of microcebus murinus (primate, lemurian). | the distribution of neuropeptide y (npy) in the brain of the lemur microcebus murinus was determined by immunocytochemistry with the aid of a highly specific antiserum against synthetic porcine npy. when compared with previous immunohistochemical data obtained in primates and other mammalian species, the localization of npy-immunoreactive (ir) structures in the microcebus murinus brain revealed particular features. (1) numerous npy-ir perikarya and a dense network of ir nerve terminals were foun ... | 1990 | 2212108 |
| prosimian hemoglobins--v. the primary structures of the alpha-i, alpha-ii and beta-hemoglobin chains of hapalemur griseus, with a note on the classification of microcebus. | 1. the duplicated adult hemoglobins were isolated from a mature hapalemur griseus and the constituent chains prepared. sequence analysis of the isolated alpha-globins showed that the alpha-i and alpha-ii chains differed by a glycine for lysine substitution at position 15. 2. the complete amino acid sequence of the single adult beta-globin of hapalemur griseus was determined. the beta-globin sequence of hapalemur griseus clusters with those of other authentic lemurs, and is clearly separated from ... | 1990 | 2123766 |
| [presence of neuritic plaques and neurofibrillary changes in the cerebral cortex of an aged lemuride primate]. | some aged microcebus murinus brains (8 to 11-years old animals) displayed a dramatic atrophy particularly in the neocortex, hippocampus, basal ganglia, hypothalamus, brainstem and cerebellum, associated with a conspicuous increase in the size of the cerebral ventricles. these morphological changes were accompanied by certain histological profiles indicative of pathology. in the cortex, these histological changes consisted of (1) a large number of neuritic plaques formed by degenerated neurites s ... | 1991 | 1913260 |
| senile plaques and neurofibrillary changes in the brain of an aged lemurian primate, microcebus murinus. | in some aged microcebus brains (8- to 11-year-old animals) dramatic atrophy is found, particularly of the cortex, the hippocampus, the basal ganglia, the brainstem and the cerebellum, associated with a conspicuous increase in the size of the cerebral ventricles. these morphological changes are accompanied by certain histological profiles indicative of pathology. in the cortex, these histological changes consist of 1) a large number of senile plaques composed of degenerated neurites sometimes sur ... | 1992 | 1542387 |
| environmental and social determinants of sexual function in the male lesser mouse lemur (microcebus murinus). | environmental factors that regulate the sexual activity of male lesser mouse lemurs have been studied experimentally with more than 60 captive animals over an 8-year period. in this nocturnal malagasy prosimian, variation in day length is the primary factor controlling seasonal sexual activity. plasma testosterone concentrations were low (= 9 ng/ml) during short days and reached 60 ng/ml during long days (> 12-hour day). this cyclic pattern persists unchanged when artificial photoperiodic rhythm ... | 1992 | 1473776 |
| chromosomal evolution in malagasy lemurs. i. chromosome banding studies in the genuses lemur and micrcebus. | the successive use of several banding methods permitted us to compare the karyotypes of six malagasy lemurs: microcebus murinus, lemur fulvus fulvus, l. f. collaris, l. f. albocollaris, l. macaco, and l. mongoz. a correspondence can be found among all clearly identifiable chromosomes. based on rearrangements of some of the chromosomes, the karyotype of m. murinus seems to be closest to that of the hypothetical common ancestor. the karyotype of l. f fulvus, which is nearly identical to that of m. ... | 1976 | 828095 |
| chromosomal evolution in primates: tentative phylogeny from microcebus murinus (prosimian) to man. | the karyotypes of more than 60 species of primates are studied and compared, with the use of almost all existing banding techniques. there is a very close analogy of chromosome banding between the simians studied and man. the quantitative or qualitative variations detected all involve the heterochromatin. it is very likely that all the euchromatin (nonvariable r and q bands) is identical in all the species. approximately 70% of the bands are common to the simians and to the lemurs (prosimians). ... | 1979 | 112030 |
| seasonal and social determinants of urinary catecholamines in the lesser mouse lemur (microcebus murinus, cheirogaleinae, primates). | | 1979 | 38043 |
| immunocytochemical characterization of tau proteins during cerebral aging of the lemurian primate microcebus murinus. | the immunocytochemistry of tau proteins in the cortical pyramidal neurons of the adult microcebes has been studied, using antibodies against human normal and pathological tau proteins. some changes related to the age and to some pathologies were observed. in fact, during the adult life, tau proteins appeared as very thin granulations scattered in the whole neuronal cytoplasm. with age, a part of these proteins aggregated and became like thick granules at the neuron periphery; the distribution wa ... | 1995 | 7757807 |
| effects of aging upon recent memory in microcebus murinus. | four young (2 to 4-year-old) and four aged (9 to 10-year-old) grey mouse lemurs (microcebus murinus) were given a simple visual discrimination task, and a delayed response visual discrimination task with variable retention delay. the response to the test is a motor one, that consists of choosing one out of four corridors of an apparatus based upon the degree of illumination. the aged animals did not show any learning deficiency, and were capable of memorizing the task for several months. however ... | 1995 | 7599242 |
| immunocytochemical characterization of tau proteins during cerebral aging of the lemurian primate microcebus murinus. | the immunocytochemistry of tau proteins in the cortical pyramidal neurons of the adult microcebes has been studied, using antibodies against human normal and pathological tau proteins. some changes related to the age and to some pathologies were observed. in fact, during the adult life, tau proteins appeared as very thin granulations scattered in the whole neuronal cytoplasm. with age, a part of these proteins aggregated and became like thick granules at the neuron periphery; the distribution wa ... | 1995 | 7583762 |
| the early development of the nervous system in staged insectivore and primate embryos. | the early development of the nervous system was studied in stage embryos of hemicentetes semispinosus, microcebus murinus, alouatta seniculus, cebus appella, cebus albifrons, macaca mulatta, and homo sapiens. the specimens were assigned to carnegie stages 11-13. serial transverse sections were examined and graphic reconstructions were prepared. the early development of the neural tube is basically similar in all the species investigated but differences in detail are noticeable. the mesencephalic ... | 1980 | 7440789 |
| stress-effects in microcebus murinus. | histological investigations were made over a 10-year period on 164 lesser mouse lemurs that died spontaneously in captivity. the principal lesions found were chronic nephrosis with nephritis which affects 90% of the animals, myocardial necrosis, respiratory insufficiency induced by interstitial pneumonia, fatty changes in the liver, and splenic and gastric lesions. the following are associated with these pathologies: progressive hypothyroidism, stable hypercorticism, slight medulloadrenal hypera ... | 1982 | 7141352 |
| gene mapping of microcebus murinus (lemuridae): a comparison with man and cebus capucinus (cebidae). | the karyotype of microcebus murinus (mim) (lemuridae) is considered by dutrillaux (1979) as the closest to the karyotype ancestral to all primates. a large number of homoeologies exists between the banding patterns of mim chromosomes and those of man (hsa). we report a comparison of the gene maps of these two species which confirms most of these homoeologies. fifteen cell hybrids were obtained by fusing mim fibroblasts and an hprt- chinese hamster cell line. twenty-seven enzyme markers were inve ... | 1982 | 6957281 |
| chromosome banding analogies between a prosimian (microcebus murinus), a platyrrhine (cebus capucinus), and man. | the comparative study of the karyotypes of microcebus (lemur, cheirogaleid) and cebus (platyrrhini, ceboid) shows important similarities between nearly all large chromosomes of these two genera. since a relationship has been previously found between the karyotypes of homo and cebus, a correspondence may be found between many chromosomes of man and those of lemurs. this study enlarges the field of comparative cytogenetics at the level of the primate order. | 1980 | 6768303 |
| new gene assignments in the rabbit (oryctolagus cuniculus). comparison with other species. | nineteen cell hybrids were obtained by fusing rabbit (oryctolagus cuniculus, ocu) fibroblasts and a chinese hamster cell line hgprt-. eleven enzymatic markers were previously investigated (soulié and grouchy 1982); seven of these could be assigned (ldha, ldhb, tpi, pepb, np, itp, and g6pd). two assignments were uncertain (mdh2 and guk). two markers could not be assigned (mdh1 and pgd). seven further markers were investigated and are the subject of this report. six could be assigned: galt to chro ... | 1983 | 6572613 |
| effects of long-term grouping on serum cortisol levels in microcebus murinus (prosimii). | the influence of social interactions on plasma cortisol was studied in captive microcebus murinus, a prosimian primate. regardless the group composition, there is an annual variation in cortisol levels characterized by an autumn peak that coincides with the fattening and sexual resting period. the beginning of activity, early in january, is accompanied by a fall in cortisol levels. cortisol levels are higher in females than in males both in pairs and in heterosexual groups. in paired animals, me ... | 1984 | 6489945 |
| biochemical characterization of tau proteins during cerebral aging of the lemurian primate microcebus murinus. | tau proteins extracted from the brain of 12 adult microcebes ranging from 2 to 9 years old were characterized by western blots, using immunological probes against normal and pathological human tau proteins. in microcebes, the molecular weight of tau proteins increases during aging, with variants of 52-54, 64, 67 kda in the young adult and variants of 60 and 70 kda in the oldest animal studied. the increase of the apparent molecular weight is due to a change of conformation and a stabilization in ... | 1995 | 7757808 |
| [similarities between cerebral amyloid plaques in aged lemurian and in human with alzheimer's disease]. | microcebus cerebral cortex has been investigated using various technics: amyloid beta-a4 protein, alpha-1 antichymotrypsin and ubiquitin immunocytochemistry, thioflavin s staining for amyloid deposition and bodian's silver impregnation not only for amyloid plaques but also for degenerated neurites; glial fibrillary acidic protein (gfap) immunocytochemistry has been also used for astrocytes. parenchymal beta-a4 amyloid is observed to be deposited in some aged microcebus cerebral cortex in three f ... | 1993 | 8019922 |
| removal of the olfactory bulbs modifies the gonadal responses to photoperiod in the lesser mouse lemur (microcebus murinus). | the sexual activity of the lesser mouse lemur, unlike that of most living primates, is clearly dependent on photoperiod. males responded to long daylengths (> 12 h light/day) by rapid testicular development and an increase in testosterone levels reaching 65.8 +/- 1.5 ng/ml (n = 12) after 3 wk of inductive photoperiod. levels were maintained unchanged until 14 wk of exposure to long photoperiod, when spontaneous gonadal regression was observed. under short daylengths, intact males exhibited regre ... | 1993 | 8353190 |
| social influences on oestrous cycle length and plasma progesterone concentrations in the female lesser mouse lemur (microcebus murinus). | plasma progesterone concentrations were recorded during one breeding season in 19 lesser mouse lemur females living in different social conditions. the oestrous cycle length and the progesterone profile mainly depended on the social environment of the female. for totally isolated females, the oestrous cycle lasted 38 +/- 5.7 days and included a 25-30-days spontaneous luteal phase with a progesterone peak about 100 ng/ml between the 20th and 25th days after oestrus, and a prolonged preovulatory p ... | 1986 | 3723475 |
| castration affects the emission of an ultrasonic vocalization in a nocturnal primate, the grey mouse lemur (microcebus murinus). | male primates have evolved particular displays to advertise male fitness. in nocturnal prosimians it was assumed that such displays (vocal advertisement, marking behaviour) are hormonally dependent and influenced by olfactory cues of a receptive female. to test this assumption mouse lemur males of different gonadal status (males castrated as adults, normal males), or of varying olfactory input (males vomeronasalectomized or bulbectomized as adults) were paired with intact "stimulus" preoestrous ... | 1996 | 8873238 |
| cholinergic axonal dystrophy and mitochondrial pathology in prosimian primates. | progressive cholinergic axonal dystrophy, cholinergic denervation, and generalized gliosis begin in the prosimian primate species otolemur at 10% of maximum life span. in these same animals, extensive cerebral beta-amyloidosis follows relatively more abruptly at 50% of maximum life span. in contrast, even at maximum life span, the prosimian primate species galago senegalensis moholi, microcebus murinus, and eulemur fulvus collaris and insectivore species t. belangeri are either spared or much le ... | 1996 | 8912903 |
| molecular cloning, sequencing, and brain expression of the presenilin 1 gene in microcebus murinus. | the cdna encoding the microcebus murinus presenilin 1 protein (psi) was cloned by rt-pcr from a brain cdna library using various combinations of oligonucleotide primers designed on the basis of the human nucleotide sequence. analysis of five clones isolated from two positive combinations revealed that the deduced open reading frame encodes two protein isoforms of 467 and 463 amino acid residues. the shorter isoform lacked the four residues vrsq in the n-terminal region and like the 467 amino aci ... | 1996 | 8920931 |
| beta-amyloid protein precursor in microcebus murinus: genotyping and brain localization. | senile plaques characterized by beta-amyloid protein (a beta) deposits around dystrophic neurites and glial cells are more abundant in the cerebral cortical parenchyma of alzheimer's disease (ad) patients than in the aged population. four different mutations in the amyloid precursor protein (app) gene have been directly involved in a few cases of familial ad with early onset (before 60 years). previous studies have shown that microcebus murinus, a nonhuman primate, also develops analogous deposi ... | 1996 | 8980017 |
| change in photoperiodic cycle affects life span in a prosimian primate (microcebus murinus). | the lesser mouse lemur, a small prosimian primate, exhibits seasonal rhythms strictly controlled by photoperiodic variations. exposure to day lengths shorter than 12 h results in complete sexual rest, fattening, lethargy, and reduced behavioral activities; whereas exposure to day lengths greater than 12 h induces sexual activity, an increase in behavioral activities, and high hormonal levels. the objective of this study was to test whether long-term acceleration of seasonal rhythms may affect su ... | 1997 | 9090567 |
| quantitative analysis of tau protein-immunoreactive accumulations and beta amyloid protein deposits in the cerebral cortex of the mouse lemur, microcebus murinus. | recent studies have revealed the presence of tau protein-immunoreactive accumulations and beta amyloid protein (a beta) deposits in the cerebral cortex of the aged mouse lemur, microcebus murinus. to examine the age-related evolution of these changes and compare their regional distribution to that reported for humans and nonhuman primates with alzheimer's disease lesions, we performed a quantitative analysis of a large series of mouse lemurs aged from 1 to 13 years. the prevalence and density of ... | 1997 | 9255387 |
| diurnal variations in plasma testosterone concentrations in the male lesser mouse lemur (microcebus murinus). | in 6 isolated adult male lesser mouse lemurs, concentrations of testosterone in plasma were determinated at 6-h intervals over a 24-h period. blood samples were collected at monthly intervals and for a period of 12 months under natural photoperiod. in this nocturnal prosimian, there were no apparent diurnal changes in testosterone concentrations during the non-breeding season (autumn). during seasonal sexual activity (january-august), diurnal changes in testosterone concentrations were character ... | 1985 | 4040572 |
| effect of vomeronasal organ removal on male socio-sexual responses to female in a prosimian primate (microcebus murinus). | in most mammals, olfactory cues play an important role in regulating socio-sexual behaviors, but the relative contributions of the main olfactory system and the vomeronasal system remain unclear. the lesser mouse lemur, a nocturnal prosimian, possesses well-developed chemosensory structures, including a functional vomeronasal organ (vno). in this primitive primate, social communication and competition between males for priority access to receptive females includes reliance on urinary chemical cu ... | 1997 | 9333193 |
| age dependence of the t2-weighted mri signal in brain structures of a prosimian primate (microcebus murinus). | mouse lemurs (microcebus murinus) are prosimian primates described to be convenient models of brain aging. we observed very high correlations between the t2-weighted magnetic resonance imaging (mri) signal decrease and the natural logarithm of age in the basal ganglia. the correlation coefficient was higher for the pallidum (r = 0.95, p < 0.0001) than for other structures. we suggest that the ratio of the pallidum intensity divided by the amygdala and temporal lobe intensity should be a valuable ... | 1997 | 9453221 |
| acoustically dimorphic advertisement calls separate morphologically and genetically homogenous populations of the grey mouse lemur (microcebus murinus). | sexual advertisement calls of male mouse lemurs from two neighbouring demes in a dry deciduous forest of western madagascar were recorded during the breeding season. demes were located about 1.5 km apart with no geographic barrier between them. they were characterised morphometrically and genotyped by rapd fingerprinting. according to univariate and multivariate statistical analysis, demes differed neither in body measurements, nor in the banding patterns produced by rapd fingerprinting. the aco ... | 1998 | 9595693 |
| astroglial interlaminar processes in the cerebral cortex of prosimians and old world monkeys. | previous observations have shown that astrocytes with interlaminar processes are present in the cerebral cortex of humans and new and old world monkeys, but not in the rodent. the present report furthers the analysis of possible evolutionary aspects regarding the expression of such astroglial features. a comparison between young and adult microcebus murinus, a prosimian, and old world monkeys (macaca mulatta and papio hamadryas) is presented. brain samples were processed for glial fibrillary aci ... | 1998 | 9623670 |
| a stereotaxic atlas of the grey lesser mouse lemur brain (microcebus murinus). | in response to the growing interest in the prosimian microcebus murinus for studies on cerebral aging, the stereotaxic atlas of its brain was carried out in view of further anatomical, biochemical, electrophysiological, and behavioral investigations as well as for therapeutic experiments. this primate, which could be a valuable model for neuroscientific studies in various domains, presents numerous physiological advantages (e.g., size, cost, and ability to breed) compared to rodents, which can b ... | 1998 | 9639030 |
| topographical localization of iron in brains of the aged fat-tailed dwarf lemur (cheirogaleus medius) and gray lesser mouse lemur (microcebus murinus). | iron deposits in the human brain are characteristic of normal aging but have also been implicated in various neurodegenerative diseases. among nonhuman primates, strepsirhines are of particular interest because hemosiderosis has been consistently observed in captive aged animals. in particular, the cheirogaleids, because of their small size, rapid maturity, fecundity, and relatively short life expectancy, are a useful model system for the study of normal and pathological cerebral aging. this stu ... | 1998 | 9651651 |
| sex-specific usage patterns of sleeping sites in grey mouse lemurs (microcebus murinus) in northwestern madagascar. | sleeping sites are a potentially important resource for grey mouse lemurs since they are confronted with high daily temperature fluctuations and a high predation pressure. in order to determine the existence and degree of resource competition, sleeping site characteristics, locations, and usage patterns as well as sleeping group compositions were investigated in a 3 month field study in a dry deciduous forest of northwestern madagascar. the daily sleeping sites of females were on average better ... | 1998 | 9730214 |
| age-related effects on reproductive function and sexual competition in the male prosimian primate, microcebus murinus. | in the male lesser mouse lemur (microcebus murinus), a polygamous long-day breeder of which the life span may reach 12-14 years, the effects of aging on socio-sexual relationships were studied on 44 captive animals of various ages. in this primate, new dominance relationships must be established at the beginning of each breeding season. during the breeding season induced by exposure to artificial long days, preoestrous females were introduced into cages of paired males to elicit sexual competiti ... | 1998 | 9761226 |
| cloning of the presenilin 2 cdna and its distribution in brain of the primate, microcebus murinus: coexpression with betaapp and tau proteins. | a 1340-bp cdna fragment encoding the lemurian presenilin 2 protein (ps2) was isolated from a microcebus murinus brain cdna library by pcr using oligonucleotide primers based on the nucleotide sequence of the human gene. analysis of five isolated clones showed that the sequence encoded a 448-amino-acid open reading frame, 95.5% identical to the human and 93.5% identical to the mouse presenilin 2 sequences. however, neither the localization of the 2 positions in ps2 nor that of the 43 positions in ... | 1998 | 10069575 |
| topographical localization of lipofuscin pigment in the brain of the aged fat-tailed dwarf lemur (cheirogaleus medius) and grey lesser mouse lemur (microcebus murinus): comparison to iron localization. | the present study was undertaken to explore the distribution of lipofuscin in the brain of cheirogaleids by autofluorescence and compare it to other studies of iron distribution. aged dwarf (cheirogaleus medius) and mouse (microcebus murinus) lemurs provide a reliable model for the study of normal and pathological cerebral aging. accumulation of lipofuscin, an age pigment derived by lipid peroxidation, constitutes the most reliable cytological change correlated with neuronal aging. brain section ... | 1999 | 10466576 |
| "rodent-like" and "primate-like" types of astroglial architecture in the adult cerebral cortex of mammals: a comparative study. | previous observations disclosed that astroglia with interlaminar processes were present in the cerebral cortex of adult new and old world monkeys, but not in the rat, and scarcely in the prosimian microcebus murinus. the present report is a more systematic and comprehensive comparative analysis of the occurrence of such processes in the cerebral cortex of several mammalian species. brain samples were obtained from adult individuals from the following orders: carnivora (canine), rodentia (rat and ... | 2000 | 10672363 |
| mri description of cerebral atrophy in mouse lemur primates. | we assessed cerebral atrophy in mouse lemur primates (microcebus murinus) by estimating csf volume in their brains from 4.7 tesla t2-weighted magnetic resonance images. thirty animals aged from 1 to 10.3 years were imaged, 14 of them were followed for up to 2 years. seven of these animals were examined for neuropathology. in 12 out of 17 animals older than 3.5 years, csf volumes were increased. a subgroup of six animals had severe atrophy of the temporal lobe. another subgroup of five animals di ... | 2000 | 10794852 |
| sociality in the gray mouse lemur (microcebus murinus) in northwestern madagascar. | the mating system and social organization of the gray mouse lemur (microcebus murinus) was investigated in two three-month field studies (covering a period before, during, and after the first mating season) in ampijoroa, northwestern madagascar. the spatial and temporal distribution of the sexes within a population was studied using mark/recapture techniques and radiotelemetry to assess possible contest or scramble competition between the males. sociality was inferred from the occurrence and pro ... | 2000 | 10811438 |
| a preliminary study of spatial distribution and mating system of pygmy mouse lemurs (microcebus cf. myoxinus). | according to current hypotheses on the evolution of life history traits and social systems of malagasy lemurs, nocturnality is associated with a solitary lifestyle and a polygynous or promiscuous mating system. recent studies, however, have indicated that this may not be true of all lemurs. the goal of this study was to investigate the sociality and the mating system of pygmy mouse lemurs (microcebus cf myoxinus), which are the smallest known primates, and which retain characteristics of the mos ... | 2000 | 10811439 |
| melatonin and methimazole mimic short-day-induced fattening in gray mouse lemurs. | short-day-induced fattening was investigated in the small nocturnal primate microcebus murinus. animals were either transferred from long photoperiod (lp) to short photoperiod (sp) or maintained in lp and submitted to various treatments. animals fed daily on 40 microg of melatonin (mel) at two different times showed a significant increase in body mass compared to lp-exposed animals. this weight gain was more marked in animals fed with mel 2 h before night onset, suggesting a critical period arou ... | 2003 | 12954394 |
| comparative morphology and histochemistry of glands associated with the vomeronasal organ in humans, mouse lemurs, and voles. | the vomeronasal organ (vno) is a chemosensory structure of the vertebrate nasal septum that has been recently shown to exist in nearly all adult humans. although its link to reproductive behaviors has been shown in some primates, its functionality in humans is still debated. some authors have suggested that the human vno has the capacity to detect pheromones, while others described it as little more than a glandular pit. however, no studies have utilized histochemical techniques that would revea ... | 2000 | 10967540 |
| comparative distribution of mrna encoding the growth hormone secretagogue-receptor (ghs-r) in microcebus murinus (primate, lemurian) and rat forebrain and pituitary. | the forebrain and pituitary sites of synthesis of growth hormone secretagogue-receptor mrna were identified in four adult lemurs (microcebus murinus) by in situ hybridisation performed with a radiolabeled crna probe transcribed from human growth hormone secretagogue-receptor cdna. the crna sense and antisense probes were hybridised to cryostat sections containing structures extending from the rostral hypothalamus to its caudal limit as defined by the mammillary bodies. the pituitary gland and ar ... | 2001 | 11116232 |
| photoperiod-induced changes in energy balance in gray mouse lemurs. | to cope with the 6-month dry winter occurring in its natural habitat, the gray mouse lemur (microcebus murinus), a malagasy prosimian primate, exhibits a pre-wintering fattening phase that has been previously demonstrated to be dependent on the photoperiod. to assess early changes in energy balance following a photoperiodic shift, food intake (fi), resting metabolic rate (rmr), plasma triglycerides, plasma thyroxine and urinary excretion of cortisol were measured in 12 males and 12 females for 8 ... | 2000 | 11150563 |
| daily energy expenditure of the grey mouse lemur (microcebus murinus): a small primate that uses torpor. | we aimed to investigate the pattern of utilisation of torpor and its impact on energy budgets in free-living grey mouse lemurs (microcebus murinus), a small nocturnal primate endemic to madagascar. we measured daily energy expenditure (dee) and water turnover using doubly labelled water, and we used temperature-sensitive radio collars to measure skin temperature (tsk) and home range. our results showed that male and female mouse lemurs in the wild enter torpor spontaneously over a wide range of ... | 2000 | 11192269 |
| the existence of the vomeronasal organ in postnatal chimpanzees and evidence for its homology with that of humans. | it is currently thought that new world monkeys, prosimians, and humans are the only primates to possess vomeronasal organs (vnos) as adults. recent studies of the human vno suggest that previous investigations on old world primates may have missed the vno. we examined nasal septa from the chimpanzee (pan troglodytes) grossly and histologically for comparison with nasal septa from humans, old world monkeys (macaca fascicularis, m. nemistrina) and prosimian primates (microcebus murinus, otolemur g ... | 2001 | 11215770 |
| identification of a unique apolipoprotein e allele in microcebus murinus; apoe brain distribution and co-localization with beta-amyloid and tau proteins. | this report is devoted to the characterization of the apolipoprotein e (apoe) in microcebus murinus. only one allele homologous to the human apoe4 allele was evidenced. the distribution of the corresponding apoe protein in the brain was found in association with the pathological proteins characteristic of alzheimer's disease (ad). immunocytochemistry revealed brain deposits of apoe in: (1) the cortical amyloid plaques; (2) the neurones of the various cortical lobes, the hippocampus and the brain ... | 1995 | 9174000 |
| response to urinary volatiles and chemosensory function decline with age in a prosimian primate. | the age-related decline in olfaction is well documented in humans. however, no data are available to date on changes in olfactory sensitivity with age in nonhuman primates. in the male gray mouse lemur (microcebus murinus), a prosimian primate, the sense of smell is of high relevance for the modulation of both behavioral and physiological functions. we first assessed the effect of aging on physiological responses to urinary cues by measuring reproductive function in adult and aged males exposed ... | 2004 | 15178157 |
| cerebral t2-weighted signal decrease during aging in the mouse lemur primate reflects iron accumulation. | 4.7 tesla t2-weighted magnetic resonance images showed a highly significant signal decrease in the pallidum, substantia nigra, putamen, and a less significant decrease in the thalamus and the caudate of aging mouse lemurs (microcebus murinus). we evaluated the contribution of iron deposits to the signal decrease comparing perls' stained histological sections of six mouse lemurs brains aged 1 to 10 years to magnetic resonance images. in young animals, none of the brain structures was stained. a l ... | 1998 | 9562505 |
| prion immunoreactivity in brain, tonsil, gastrointestinal epithelial cells, and blood and lymph vessels in lemurian zoo primates with spongiform encephalopathy. | we report on two animals of a non-human primate species eulemur fulvus mayottensis, housed in the local zoo and fed over a number of years with a food containing cattle meat, that developed serious neurological symptoms associated with prion immunoreactivity in brain and various viscera. microscopy of the brains showed neuronal vacuolation with patchy/perivacuolar immunolabelling with an abnormal isoform of prion protein (ir-prp), an important characteristic of spongiform encephalopathy. for the ... | 1997 | 9587475 |
| changes in olfactory inputs modify the energy balance response to short days in male gray mouse lemurs. | the role of olfaction/olfactory cues on photoperiodic responses was assessed in malagasy primate, the gray mouse lemur. when exposed to short photoperiod (sp), this primate demonstrates rapid changes in energy balance as adaptive anticipatory response for winter survival. to follow early changes induced by sp exposure, body mass, food intake, resting metabolism (rmr) and free thyroxin levels in plasma (t4) were measured in males abruptly transferred to sp: six intact males (controls), eight male ... | 2004 | 15642603 |
| comparison of the genetic diversity of wild and captive groups of microcebus murinus using the random amplified polymorphic dna method. | continued survival of most animal species depends on population management and active protection. it is generally agreed that, in order to avoid extinction of endangered species, ex situ and in situ conservation must be developed in tandem. however, even though many recommendations have been put forward to promote the survival of captive populations, some rapidly become extinct due to loss of genetic diversity (drift effect). genetic markers, such as random amplified polymorphic dna (rapd) marke ... | 1998 | 9595690 |
| bse infection of the small short-lived primate microcebus murinus. | eleven microcebus murinus (lemur) primates were intracerebrally or orally infected by bovine spongiform encephalopathy (bse) or macaque-adapted bse (mbse) brain homogenates. in many bse and mbse infected lemurs, but not in animals inoculated with normal bovine brain, persistent behavioral changes occurred as early as 3 months, and neurological signs as early as 13 months after infection. immunohistochemical examination of animals sacrificed during the incubation period revealed an abnormal accum ... | 2002 | 11862624 |
| quantitative assessment of testicular germ cell production and kinematic and morphometric parameters of ejaculated spermatozoa in the grey mouse lemur, microcebus murinus. | germ cell production and organization of the testicular epithelium in a prosimian species, the grey mouse lemur, microcebus murinus, was investigated to extend knowledge of comparative primate spermatogenesis. in addition, semen samples collected from adult male lemurs (body weight 53-92 g; n = 16) by rectal probe electroejaculation were evaluated using computer-assisted morphometric and kinematic analysis of spermatozoa. epididymidal spermatozoa were collected from six animals after hemicastrat ... | 2002 | 11866700 |
| brain and buffy coat transmission of bovine spongiform encephalopathy to the primate microcebus murinus. | more than 100 cases of variant cjd resulting from infections with bovine spongiform encephalopathy (bse) have accumulated in the united kingdom since 1995. concern about the possibility of secondary transmissions via blood and blood components donated by infected individuals has prompted a variety of international donor deferral policies that will continue until laboratory and epidemiologic evidence provides a consensus about potential risk. | 2002 | 12084158 |
| brown fat and nonshivering thermogenesis in the gray mouse lemur (microcebus murinus). | the gray mouse lemur microcebus murinus is a rare example of a primate exhibiting daily torpor. in captive animals, we examined the metabolic rate during arousal from torpor and showed that this process involved nonshivering thermogenesis (nst). under thermoneutrality (28 degrees c), warming-up from daily torpor (body temperature <33 degrees c) involved a rapid (<5 min) increase of o(2) consumption that was proportional to the depth of torpor (n = 8). the injection of a beta-adrenergic agonist ( ... | 2003 | 12446279 |
| characterization of calbindin-positive cones in primates. | the aim of this study is to characterize calbindin-positive photoreceptors and their opsin content in the retina of nocturnal prosimians (microcebus murinus), new world monkeys (callithrix jacchus), old world monkeys (macaca fascicularis), and humans. to identify the calbindin and opsin content of cones, combined multiple labeling with different fluorescent probes, antibodies directed against calbindin, short, and mid-long wavelength opsins, and lectin peanut agglutinin cytochemistry were used. ... | 2002 | 12453500 |
| social inhibition of seasonal fattening in wild and captive gray mouse lemurs. | due to their differential reproductive investment, males and females often exhibit high differences in energy management. the main hypothesis tested in this study is that short photoperiod-induced fattening in the small primate microcebus murinus is strongly affected by social cues. short photoperiod-induced changes in body mass, lean mass and thyroid hormone t4 plasma levels measurements were investigated in wild and captive animals. individual housing showed that both males and females are abl ... | 2005 | 16085129 |
| characterization and phylogenetic relationship of prosimian mhc class i genes. | mhc class i cdna sequences from the most divergent primate group of extant primates compared to human, the suborder strepsirrhini (prosimians), are described. the sequences are derived from the gray mouse lemur (microcebus murinus) and the ring-tailed lemur (lemur catta), which are members of the malagasy lemuriformes, as well as from the pygmy slow loris (nycticebus pygmaeus), a prosimian from east asia. the m. murinus sequences have been analyzed in detail. analysis of the expression level, g/ ... | 2002 | 12486535 |
| calpain 3 is expressed in astrocytes of rat and microcebus brain. | the calcium-dependent protease calpain is involved in numerous functions, including the control of cell survival, plasticity and motility. whereas the isoforms calpain 1 and 2 have been described as ubiquitously expressed enzymes, calpain 3 has been called "muscle-specific", although trace amounts of calpain 3 mrna have been detected by northern blot in brain homogenates. in this study, we validated antibodies raised either against the peptides that were specific for a given isoform or the pepti ... | 2003 | 12663060 |
| physical activity and balance performance as a function of age in a prosimian primate (microcebus murinus). | physical activity and balance performance were examined in gray mouse lemurs (microcebus murinus) aging from 1 to 10 years of age. home cage spontaneous activity, physical and behavioral activities in an open-field test and balance performance at the rotarod test were evaluated. in this prosimian primate, which life span reaches 8-10 years in captivity, balance performance at the rotarod test showed a clear decrease with age. latency to fall decreased from 154.7+/-13.5s in the youngest group of ... | 2003 | 12670627 |
| species-specific usage of sleeping sites in two sympatric mouse lemur species (microcebus murinus and m. ravelobensis) in northwestern madagascar. | we investigated the sleeping site ecology of two sympatric mouse lemur species (microcebus murinus and m. ravelobensis) in northwestern madagascar during the second half of the dry season with respect to the type, quality, and usage pattern of the sleeping sites, as well as to social sleeping habits and response to potential threats. the type and quality of the sleeping sites differed between the two species. m. murinus used protected wooden shelters (tree holes) more frequently than m. ravelobe ... | 2003 | 12682922 |
| ontogeny of the nasopalatine duct in primates. | ecological explanations have been put forward to account for the precocious or delayed development of patency in ducts leading to the vomeronasal organ (vno) in certain mammals. perinatal function may be related, in part, to the patency or fusion of the vomeronasal and nasopalatine (npd) ducts. however, few studies have focused on npd development in primates, which generally have a prolonged period of dependence during infancy. in this study we examined 24 prenatal primates and 13 neonatal prima ... | 2003 | 12923897 |
| daily hypothermia in captive grey mouse lemurs (microcebus murinus): effects of photoperiod and food restriction. | the grey mouse lemur (microcebus murinus) is a small nocturnal primate exhibiting daily torpor. in constant ambient temperature (22-24 degrees c), body temperature (tb) and locomotor activity were monitored by telemetry in animals exposed to short (sp: 10 h light/day) or long (lp: 14 light/day) photoperiods. they were first fed ad libitum for 8 days and then subjected to 80% restricted feeding for 8 more days. during ad libitum feeding, locomotor activity was significantly lower in sp-exposed an ... | 2003 | 12941640 |
| olfactory bulbectomy modifies photic entrainment and circadian rhythms of body temperature and locomotor activity in a nocturnal primate. | studies on rodents have emphasized that removal of the olfactory bulbs modulates circadian rhythmicity. using telemetric recordings of both body temperature (tb) and locomotor activity (la) in a male nocturnal primate, the gray mouse lemur, the authors investigated the effects of olfactory bulbectomy on (1) the circadian periods of tb and la in constant dim light condition, and (2) photic re-entrainment rates of circadian rhythms following 6-h phase shifts of entrained light-dark cycle (ld 12:12 ... | 2003 | 14582855 |
| regional atrophy in the brain of lissencephalic mouse lemur primates: measurement by automatic histogram-based segmentation of mr images. | age-related regional cerebral atrophy was evaluated in a small lissencephalic primate, model of cerebral aging. twelve mouse lemurs (microcebus murinus), ages 1.9-10.9 years (maximum life span: 12 years), were studied. 3d inversion-recovery fast spin-echo mr images (isotropic resolution = 234 mum) were recorded at 4.7 t with a surface coil actively decoupled from the transmitting birdcage probe. the surface coil-related sensitivity gradient was corrected by normalization with images from an agar ... | 2003 | 14587009 |
| mating system in mouse lemurs: theories and facts, using analysis of paternity. | among nocturnal malagasy prosimians, the grey mouse lemur (microcebus murinus) is considered a solitary species which has a promiscuous mating system. indirect indicators, such as the lack of sexual dimorphism, the overlapping of male and female home ranges with each other, the synchronism of seasonal oestrus and the high relative testes size of males, support the presence of sperm competition. in captivity, an intense sexual precopulatory competition develops among males, leading to the emergen ... | 2003 | 14605478 |
| behavioral study in the gray mouse lemur (microcebus murinus) using compounds considered sweet by humans. | this study presents the results from two-bottle preference (tbp) tests performed on the gray mouse lemur (microcebus murinus), a small malagasy primate. we found that of 18 compounds considered sweet by humans, m. murinus preferred only six: d-tryptophan, dulcin, fructose, sucrose, sc45647, and xylitol. the animals neither preferred nor rejected acesulfame-k, alitame, aspartame, n-4-cyanophenyl-n'-cyanoguanidineacetate (ccga), cyanosuosan, cyclamate, monellin, saccharin, suosan, super-aspartame, ... | 2004 | 14752812 |
| are age-related deficits in balance performance mediated by time of day in a prosimian primate (microcebus murinus)? | we examined the effects of age and time of day on balance performance in the gray mouse lemur (microcebus murinus) in relation to body temperature variations. groups of young, adult and aged animals were entrained to either short (sp, l/d 10/14) or long photoperiod (lp, l/d 14/10) and tested in the accelerating rotarod at three phases of their light/dark cycle (beginning and end of the light phase, beginning of the dark phase). in addition, for each test, rectal temperature (tr) was measured. un ... | 2004 | 15130679 |
| multiple groups of endogenous betaretroviruses in mice, rats, and other mammals. | betaretroviruses exist in endogenous and exogenous forms in hosts that are widely distributed and evolutionarily distantly related. here we report the discovery and characterization of several previously unknown betaretrovirus groups in the genomes of mus musculus and rattus norvegicus. each group contains both mouse and rat elements, and several of the groups are more closely related to previously known betaretroviruses from nonmurine hosts. some of the groups also include members from hosts wh ... | 2004 | 15140976 |
| female dominance in captive gray mouse lemurs (microcebus murinus). | female dominance or female feeding priority seem to be characteristic for many lemur species, but are rare traits in other primates and mammals in general. the nocturnal lemur species, however, are underrepresented in the quantitative studies on social dominance. the aim of this study is to investigate the pattern of intersexual dominance relationships in the gray mouse lemur (microcebus murinus), a species that is generally thought to possess a number of ancestral lemur traits. the context, dis ... | 2001 | 11468749 |
| first experimental evidence for female mate choice in a nocturnal primate. | female mate choice can be hypothesised in most nocturnal primates, since females show a higher investment in their offspring than males. the aim of this experimental study was to investigate if female grey mouse lemurs perform mate choice and whether age, relatedness (to the male), or male advertisement call activity systematically influence their decisions. a two-way mate choice design was developed in which females could choose between two males. mate choice was deduced from the time spent in ... | 2004 | 15241637 |
| short and mid-wavelength cone distribution in a nocturnal strepsirrhine primate (microcebus murinus). | strepsirrhines are of considerable interest for understanding the evolution of cone photoreceptors because they represent the most ancestral living primates. the retina of nocturnal strepsirrhines is reported to contain a single population of medium/long wavelength (mw/lw) cones whereas short wavelength (sw) cones are totally absent. the area centralis of nocturnal strepsirrhines also lacks the degree of central specialization seen in the fovea of diurnal primates. in this study of a nocturnal s ... | 2001 | 11559903 |
| artificially accelerated aging by shortened photoperiod alters early gene expression (fos) in the suprachiasmatic nucleus and sulfatoxymelatonin excretion in a small primate, microcebus murinus. | in mammals, a number of anatomical and functional changes occur in the circadian timing system with aging. in certain species, aging can be modified by various factors which induce a number of pathological changes. in a small primate, the gray mouse lemur (microcebus murinus), long-term acceleration of seasonal rhythms by exposing the animals to a shortened photoperiodic regime (up to 2.5 times the natural photoperiodic regime) alters longevity, based on survival curves and morphological changes ... | 2001 | 11672607 |
| daily hypothermia and torpor in a tropical primate: synchronization by 24-h light-dark cycle. | to study the temporal organization of daily hypothermia and torpor in a nocturnal malagasy primate, the gray mouse lemur, body temperature (t(b)) and locomotor activity were recorded using telemetry on 39 males held in 24-h light-dark cycles of different photoperiods. under free-running condition, the circadian t(b) and locomotor activity rhythms had a period shorter than 24 h. circadian daily hypothermia started by a rapid drop in t(b) (0.24 degrees c/10 min) at the end of subjective night (13 ... | 2001 | 11705779 |
| age effect on olfactory discrimination in a non-human primate, microcebus murinus. | in order to characterize age-related cognitive changes, olfactory discrimination was assessed in microcebus murinus, a prosimian primate. we compared young (n = 10) and old (n = 8) animals for individual performance on three olfactory tasks. animals had to perform a detection, a transfer, and a reversal learning task using a go, no go conditioning procedure. no differences were observed between the two groups, indicating that aging is not inevitably associated with a decline in cognitive functio ... | 2006 | 15955599 |
| microsatellite analyses reveal fine-scale genetic structure in grey mouse lemurs (microcebus murinus). | information on genetic structure can be used to complement direct inferences on social systems and behaviour. we studied the genetic structure of the solitary grey mouse lemur (microcebus murinus), a small, nocturnal primate endemic to western madagascar, with the aim of getting further insight on its breeding structure. tissue samples from 167 grey mouse lemurs in an area covering 12.3 km2 in kirindy forest were obtained from trapping. the capture data indicated a noncontinuous distribution of ... | 2005 | 15969720 |
| age effects on pheromone induced fos expression in olfactory bulbs of a primate. | in the gray mouse lemur, a prosimian primate, aging is associated with a reduction of olfactory behaviors and sexual stimulation. to assess the effect of aging on the central response to pheromone stimulation in this primate, we measured the c-fos expression in the main and accessory olfactory bulbs of adult and aged male mouse lemurs, following exposure to the volatile phase of urine from proestrous females. in adults, pheromone exposure increased the number of fos-positive neurons in the main ... | 2005 | 15973154 |
| aging and season affect plasma dehydroepiandrosterone sulfate (dhea-s) levels in a primate. | in humans, plasma concentration of dehydroepiandrosterone sulfate (dhea-s) declines with age and is considered as a potential predictor of longevity. dhea-s is apparently unique to primates but few species of nonhuman primates have been studied for age-related changes in dhea-s. in a short living primate, the grey mouse lemur (longevity 10-13 years), metabolic and physiological parameters exhibit high seasonal changes with age-related decrease in amplitude. from 8 month- to 11-year-old males (n ... | 2005 | 16019179 |
| redistribution of cb1 cannabinoid receptors during evolution of cholinergic basal forebrain territories and their cortical projection areas: a comparison between the gray mouse lemur (microcebus murinus, primates) and rat. | endocannabinoid signaling, mediated by presynaptic cb1 cannabinoid receptors on neurons, is fundamental for the maintenance of synaptic plasticity by modulating neurotransmitter release from axon terminals. in the rodent basal forebrain, cb1 cannabinoid receptor-like immunoreactivity is only harbored by a subpopulation of cholinergic projection neurons. however, endocannabinoid control of cholinergic output from the substantia innominata, coincident target innervation of cholinergic and cb1 cann ... | 2005 | 16129564 |
| shortened seasonal photoperiodic cycles accelerate aging of the diurnal and circadian locomotor activity rhythms in a primate. | the gray mouse lemur (microcebus murinus), a prosimian primate, exhibits seasonal rhythms strictly controlled by photoperiodic variations. previous studies indicated that longevity can be altered by long-term acceleration of seasonal rhythms, providing a model for assessing various aspects of aging. to assess the effect of aging and accelerated aging on the circadian system of this primate, we compared the circadian rhythm of the locomotor activity in adult mouse lemurs (2-4.5 years, n = 9), age ... | 2005 | 16267385 |
| relationship between urinary estrogen levels before conception and sex ratio at birth in a primate, the gray mouse lemur. | | 2005 | 16308334 |
| microcebus murinus: a useful primate model for human cerebral aging and alzheimer's disease? | age-associated dementia, in particular alzheimer's disease (ad), will be a major concern of the 21st century. research into normal brain aging and ad will therefore become increasingly important. as for other areas of medicine, the availability of good animal models will be a limiting factor for progress. given the complexity of the human brain, the identification of appropriate primate models will be essential to further knowledge of the disease. in this review, we describe the features of brai ... | 2006 | 16507003 |
| [aging and biological rhythms in primates]. | all living organisms exhibit rhythmic activities in a wide variety of endocrine and behavioural parameters. these biological rhythms are endogenously generated by a circadian clock, and they are entrained by cyclic variations of environmental factors called synchronizers. aging is associated with changes in amplitude and temporal organization of many daily and seasonal rhythms. in humans, daily rhythms of sleep, thermoregulation and hormonal secretion are severely altered with aging. except in h ... | 2006 | 16527209 |
| non-invasive blood sampling from primates using laboratory-bred blood-sucking bugs (dipetalogaster maximus; reduviidae, heteroptera). | primates are easily stressed by the conventional veterinary blood sampling routine and consequently, measured blood parameters may be biased. in this study, we tested blood-sucking bugs (dipetalogaster maximus) on one lemur and two ape species (microcebus murinus, pongo abelii, pan paniscus) as an alternative, non-invasive technique for bleeding primates. within time periods of between 6 and 62 min we obtained blood volumes of 0.01-2.4 ml in 11 out of 12 trials from all three species. therefore, ... | 2006 | 16741605 |
| the role of survival for the evolution of female philopatry in a solitary forager, the grey mouse lemur (microcebus murinus). | it is widely accepted that natal philopatry is a prerequisite for the evolution of sociality. the life-history hypothesis maintains that longevity of adults results in extended territory tenure and thus limits breeding vacancies for offspring, which makes natal philopatry more likely. here, we tested the importance of longevity for natal philopatry in females of a basal primate, the grey mouse lemur (microcebus murinus). this species is regarded as being solitary due to its foraging habits but w ... | 2006 | 16959645 |
| aging affects executive functions and memory in mouse lemur primates. | the decline of cognitive capacities with age in mouse lemur primates (microcebus murinus) was assessed. eight young adults (2-4 years) and nine aged adults (7-11 years) were examined on tasks designed to measure executive functions, procedural and declarative memory. the mouse lemurs were tested on the go-no go successive discrimination task, set shifting tasks (including extra-dimensional shift and reversal discrimination) and a spatial rule-guided discrimination task. there were four major fin ... | 2007 | 17084573 |
| phylogenetic relationships among the lorisoidea as indicated by craniodental morphology and mitochondrial sequence data. | the phylogeny of the afro-asian lorisoidea is controversial. while postcranial data attest strongly to the monophyly of the lorisidae, most molecular analyses portray them as paraphyletic and group the galagidae alternately with the asian or african lorisids. one of the problems that has bedevilled phylogenetic analysis of the group in the past is the limited number of taxa sampled for both ingroup families. we present the results of a series of phylogenetic analyses based on 635 base pairs (bp) ... | 2007 | 17171677 |
| ocular findings in two colonies of gray mouse lemurs (microcebus murinus). | to determine the incidence and describe the characteristics of cataracts and other ocular lesions found in two colonies of gray mouse lemurs (microcebus murinus). | 2007 | 17204127 |
| first evidence for relocation of stationary food resources during foraging in a strepsirhine primate (microcebus murinus). | field observations suggest that the diet of the malagasy gray mouse lemur consists not only of non-stationary animal prey (invertebrates or small vertebrates), but also of stationary food resources such as gum or homopteran larvae secretions (hls). we studied the foraging behavior of five mouse lemurs radiotelemetrically, each during six consecutive nights in the dry season, to explore to which extent they use these food resources and whether there is evidence for their relocation. we found that ... | 2007 | 17294428 |