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antiviral activity of petiveria alliacea against the bovine viral diarrhea virus.natural products are a relevant source of antiviral drugs. five medicinal plants used in argentina have been assayed to detect inhibition of viral growth.200212138331
cytotoxic effect of argentine medicinal plant extracts on human hepatocellular carcinoma cell line.methanolic extracts from achyrocline satureioides (dc.) lam, aristolochia macroura gomez, lithraea molleoides (vell.) engl., schinus molle l., unlike those from celtis spinosa spreng, chenopodium ambrosioides l., petiveria alliacea l., and plantago major l. showed cytotoxic activity against a human hepatocellular carcinoma cell line, hep g2. schinus molle l. was the most active (ic50=50+/-7 microg/ml). these results call for further studies of these extracts.200211849838
comparative study of the assay of artemia salina l. and the estimate of the medium lethal dose (ld50 value) in mice, to determine oral acute toxicity of plant extracts.artemia salina l. (artemiidae), the brine shrimp larva, is an invertebrate used in the alternative test to determine toxicity of chemical and natural products. in this study the medium lethal concentrations (lc50 value) of 20 plant extracts, aloe vera (l.) burm. f. (aloeaceae), artemisia absinthium l. (asteraceae); citrus aurantium l. (rutaceae); cymbopogon citratus (dc. ex nees) stapf (poaceae); datura stramonium l. (solanaceae); justicia pectoralis jacq. (acanthaceae); musa x paradisiaca l. (m ...200111695884
cox-2 inhibitory effects of naturally occurring and modified fatty acids.in the search for new cyclooxygenase-2 (cox-2) selective inhibitors, the inhibitory effects of naturally occurring fatty acids and some of their structural derivatives on cox-2-catalyzed prostaglandin biosynthesis were investigated. among these fatty acids, linoleic acid (la), alpha-linolenic acid (alpha-lna), myristic acid, and palmitic acid were isolated from a ch(2)cl(2) extract of the plant plantago major by bioassay-guided fractionation. inhibitory effects of other natural, structurally rel ...200111421736
localization of deposited polycyclic aromatic hydrocarbons in leaves of plantago.after deposition to foliage, polycyclic aromatic hydrocarbons (pahs) may remain on the leaf surface, accumulate in the cuticular wax, or diffuse into the remaining interior of the plant. in a field study, the location of deposited pahs in the leaves of two plantago species was determined. to this aim, leaves of plantago major and plantago media were divided into three fractions. first, the leaves were washed (wash-off fraction), then cuticular wax was extracted (wax fraction). finally, the remai ...200111337876
screening of several indonesian medicinal plants for their inhibitory effect on histamine release from rbl-2h3 cells.twelve alcoholic extracts and 12 hexane extracts of plant materials selected on the basis of medicinal folklore for asthma treatment in indonesia were studied for their activity in inhibiting histamine release from rbl-2h3 cells (rat basophilic leukemia cell line), a tumor analog of mast cells. the results of screening indicated that five alcoholic extracts (plantago major leaves, eucalyptus globulus leaves and fruit, cinnamomum massoiae cortex, vitex trifolia leaves) and two hexane extracts (eu ...200111297859
interaction between human complement and a pectin type polysaccharide fraction, pmii, from the leaves of plantago major l.the interaction between a pectin type polysaccharide fraction, pmii, isolated from the leaves of plantago major, and human complement was tested in two different hemolytic complement-fixation tests and in addition by two elisa methods detecting complement-activation products. sera were used as a complement source of 10 arbitrary human volunteers, individually and as a pool. the complement-fixation tests were designed to measure the concentration of the pectin necessary to inhibit 50% of the hemo ...200011119247
ursolic acid from plantago major, a selective inhibitor of cyclooxygenase-2 catalyzed prostaglandin biosynthesis.a hexane extract of plantago major was investigated by bioactivity-directed fractionation, using an in vitro cyclooxygenase-2 (cox-2) catalyzed prostaglandin biosynthesis inhibition assay, and resulted in the isolation of ursolic acid (1). this triterpenoid showed a significant cox-2 inhibitory effect, directly on the enzyme activity, with an ic50 value of 130 microm and a cox-2/cox-1 selectivity ratio of 0.6. the structural isomer oleanolic acid (2) was found to be less active than 1, with an i ...19989784154
[antioxidant properties of plant extracts].investigation of antioxidant properties of some plants was carried out. a group of plants exhibited antimicrobial activity was studied in detail. efficiency of plants as antioxidants was tested by the influence of their extracts on the yield of photochemiluminescence of gly-trp solutions. antioxidant properties were examined under conditions when their own absorption was minimized. riboflavin as additional sensitizer was used in this experiment for superoxide generation. the antioxidant effect w ...19989591094
nutritional and toxic factors in selected wild edible plants.nutritional (ascorbic acid, dehydroascorbic acid and carotenes); antinutritional and toxic components (oxalic acid, nitrate and erucic acid) were determined in sixteen popular species of wild edible plants which are collected for human consumption in southeast spain. ascorbic + dehydroascorbic acids contents were very high in several species, especially in chenopodium album l. (155 mg/100 g). carotenoid content ranged from 4.2 mg/100 g (stellaria media villars) to 15.4 mg/100 g (amaranthus virid ...19979527345
an investigation of some turkish herbal medicines in salmonella typhimurium and in the comet assay in human lymphocytes.medicinal plants play a major role in the life of turkish people and of late medicinal plant usage has increased in many countries. green plants in general contain mutagenic and carcinogenic substances, but there is little information about the biological activities of herbal medicine. in the present study, therefore, various turkish medicinal herbs were investigated for their genotoxic potential in the salmonella typhimurium microsomal activation assay and the alkaline single cell gel electroph ...19968875742
screening of medicinal plants for induction of somatic segregation activity in aspergillus nidulans.knowledge about mutagenic properties of plants commonly used in traditional medicine is limited. a screening for genotoxic activity was carried out in aqueous or alcoholic extracts prepared from 13 medicinal plants widely used as folk medicine in cuba: lepidium virginicum l. (brassicaceae): plantago major l. and plantago lanceolata l. (plantaginaceae); ortosiphon aristatus blume, mentha x piperita l., melissa officinalis l. and plectranthus amboinicus (lour.) spreng. (lamiaceae); cymbopogon citr ...19968771452
plants used in the treatment of leishmanial ulcers due to leishmania (viannia) braziliensis in an endemic area of bahia, brazil.this paper records the plants used in the treatment of cutaneous leishmaniasis due to leishmania (viannia) braziliensis (l(v)b) among the rural population of a cocoa-producing coastal area of bahia state, brazil. an enquiry conducted among a hundred patients identified 49 plants species used to treat skin ulceration caused by this leishmania species. the principal plants used are caju-branco (anacardium occidentale, anacardiaceae), used by 65% of the population, folha-fogo (clidemia hirta,melast ...19968701041
expression of the pmsuc1 sucrose carrier gene from plantago major l. is induced during seed development.a cdna clone of the plasma membrane sucrose-h+ symporter pmsuc1 from plantago major l. has been isolated and expressed in saccharomyces cerevisiae. the pmsuc1 protein was characterized in transgenic yeast and in proteoliposomes with an artificial proton-motive-force (pmf) generator. pmsuc1 catalyzes the active uptake of sucrose or maltose in the presence of pmf and is sensitive to uncouplers. unlike the extremely ph-dependent pmsuc2 sucrose-h+ symporter, pmsuc1 is relatively insensitive to chang ...19968580974
[in vitro effect against giardia of 14 plant extracts].to investigate antigiardiasic activity in plants used in mexico as antidiarrheics and/or antiparasitics.19947839013
ethnoveterinary medicines used for ruminants in british columbia, canada.the use of medicinal plants is an option for livestock farmers who are not allowed to use allopathic drugs under certified organic programs or cannot afford to use allopathic drugs for minor health problems of livestock.200717324258
[a pharmacodynamic investigation of the effect of polyholozidic substances extracted from plantago sp. on the digestive tract].from the leaves and seeds of some plantago species (plantago major, media, lanceolata) the polyholozidic fraction was separated. a statistically significant gastroprotective action was found both in the case of the polyholozide obtained from seeds and leaves in two experimental models. at higher doses a laxative action was also obtained.19902075322
studies on the individual and combined diuretic effects of four vietnamese traditional herbal remedies (zea mays, imperata cylindrica, plantago major and orthosiphon stamineus).herbal remedies are widely used in vietnam alongside modern drugs. we assessed the diuretic effect of four traditional vietnamese herbal remedies from zea mays, imperata cylindrica, plantago major and orthosiphon stamineus, all claimed to produce an increase of diuresis. no influence was recorded for the 12- and 24-h urine output or on the sodium excretion for any of the drugs when tested under standardized conditions in a placebo controlled double-blind crossover model. the present study indica ...19921434681
antiviral activity of plantago major extracts and related compounds in vitro.plantago major l., a popular traditional chinese medicine, has long been used for treating various diseases varying from cold to viral hepatitis. the aim of present study was to examine the antiviral activity of aqueous extract and pure compounds of p. major. studies were conducted on a series of viruses, namely herpesviruses (hsv-1, hsv-2) and adenoviruses (adv-3, adv-8, adv-11). the antiviral activity of ec50 was defined as the concentration achieved 50% cyto-protection against virus infection ...200212076751
structural analysis of a plant sucrose carrier using monoclonal antibodies and bacteriophage lambda surface display.monoclonal antibodies were raised and selected against recombinant plantago major pmsuc2 sucrose carrier protein. epitopes of two monoclonal antibodies (ps2-1a2 and ps2-4d4) were mapped using n-terminally truncated pmsuc2 proteins and a lambda library displaying random pmsuc2 peptides. ps2-1a2 recognizes an octapeptide close to the n-terminus of pmsuc2, ps2-4d4 binds to a decapeptide at the very c-terminus. analyses of antibody binding to yeast protoplasts with functionally active, tagged pmsuc2 ...199910405179
pmsuc3: characterization of a sut2/suc3-type sucrose transporter from plantago major.higher plants possess medium-sized gene families that encode plasma membrane-localized sucrose transporters. for several plant species, it has been shown that at least one of these genes (e.g., atsuc3 in arabidopsis and lesut2 in tomato) differs from all other family members in several features, such as the length of the open reading frame, the number of introns, and the codon usage bias. for these reasons, and because two of these proteins did not rescue a yeast mutant defective in sucrose util ...200312782730
clinical and histopathological evaluation of mdp/collagen induced arthritis rat model (mcia) after treatment with urtica dioica, plantago major and hypericum perforatum l herbal mixture.this study was done to assess the effects of urtica dioica, plantago major and hypericum perforatum l herbal mixture in the mcia rat model. in addition, a new pathological and clinical arthritis lesion assessment was developed. sprague-dawley (sd) rats were immunized with bovine type ii collagen and muramyl dipeptide (mdp). commercial herbal extracts were administered daily to the rats after the immunization for the course of experiment (90 days). rats were boosted with a second collagen-mdp emu ...200818421172
[effect of plaintain (plantago major) on the course of experimental atherosclerosis in the rabbit]. 196213861563
arabidopsis polyol transporter5, a new member of the monosaccharide transporter-like superfamily, mediates h+-symport of numerous substrates, including myo-inositol, glycerol, and ribose.six genes of the arabidopsis thaliana monosaccharide transporter-like (mst-like) superfamily share significant homology with polyol transporter genes previously identified in plants translocating polyols (mannitol or sorbitol) in their phloem (celery [apium graveolens], common plantain [plantago major], or sour cherry [prunus cerasus]). the physiological role and the functional properties of this group of proteins were unclear in arabidopsis, which translocates sucrose and small amounts of raffi ...200415598803
[experimental study of the effect of the phytomixture made of leaves of plantago major l. and achillea millenfolium l. on the secretion activity of the stomach in dogs].in this study, the author used plants with an obvious anti-ulcerous effect, which are often jointly included in gastroenterological phytomixtures. it was shown that the extract from leaves of plantago major l. has a stimulating effect on gastric secretion, mostly on parietal cells. the extract from achillea millenfolium l. reduced aggressive properties and enhanced protective properties of gastric juice. the common effect was demonstrated by the increased acid production and enhanced protective ...200516255542
rapid purification of a functionally active plant sucrose carrier from transgenic yeast using a bacterial biotin acceptor domain.a rapid and efficient method has been used for the purification of a plantago major sucrose carrier from saccharomyces cerevisiae. the c-terminal fusion of a bacterial biotin acceptor domain to the carrier protein did not interfere with the targeting to the yeast plasma membrane nor with the catalytic activity of the sucrose carrier. the chimeric construct is biotinylated by yeast cells in vivo and represents the only biotinylated protein in yeast membranes. solubilized biotinylated carrier prot ...19958543043
in vitro anti-hepatoma activity of fifteen natural medicines from canada.fifteen crude drugs, stellaria media cyrill. (caryophyllaceae), calendula officinalis l. (compositae), achillea millefolium l. (compositae), verbascum thapsus l. (scrophulariaceae), plantago major l. (plantaginaceae), borago officinalis l. (boraginaceae), satureja hortensis l. (labiatae), coptis groenlandica salisb. (ranunculaceae), cassia angustifolia vahl. (leguminosae), origanum majorana l. (labiatae), centella asiatica l. (umbelliferae), caulophyllum thalictroides mich. (berberidaceae), pice ...200212203264
[entrapment of herbal extracts in biodegradable microcapsules].the microcapsules with entrapped herbal water-soluble extracts plantago major and calendula officinalis l. (he) were prepared by lbl-adsorption of carrageenan and modificated chitosan onto caco3 microparticles with their subsequent dissolving after the treatment of edta. entrapment of he was performed by adsorption and co-precipitation techniques. the co-precipitation provided better entrapment of he compared to adsorption. in vitro release kinetics in an artificial gastric juice (agj) was studi ...200718323151
phloem loading by the pmsuc2 sucrose carrier from plantago major occurs into companion cells.high levels of mrna for the sucrose-h+ symporter pmsuc2 have been found in the vascular bundles of petioles from plantago major. the possible role of pmsuc2 in phloem loading was studied with antiserum raised against the recombinant pmsuc2 protein. this antiserum labeled a single 35-kd protein band in detergent extracts of p. major vascular bundles. it showed no cross-reaction with the p. major sucrose carrier pmsuc1, which was tested with detergent extracts from plasma membranes of transgenic y ...199512242355
evaluation of some medicinal plant extracts for antidiarrhoeal activity.the antidiarrhoeal effect of seven plant extracts namely: the aerial parts of euphorbia paralias l. (ep), bidens bipinnata l. (bb), cynachum acutum l. (cyac), diplotaxis acris (forssk.) boiss (da), convolvulus fatmensis (cf) and schouwia thebaica webb (st) and the leaves of plantago major l. (pm), was evaluated on castor oil-induced diarrhoea, gastrointestinal movement in rats (charcoal meal) and on the motility of duodenum isolated from freshly slaughtered rabbits. a significant antidiarrhoeal ...200516114083
screening of some plants used in the brazilian folk medicine for the treatment of infectious diseases.extracts of 13 brazilian medicinal plants were screened for their antimicrobial activity against bacteria and yeasts. of these, 10 plant extracts showed varied levels of antibacterial activity. piper regnellii presented a good activity against staphylococus aureus and bacillus subtilis, a moderate activity on pseudomonas aeruginosa, and a weak activity against escherichia coli. punica granatum showed good activity on s. aureus and was inactive against the other standard strains. eugenia uniflora ...200212471432
[inhibiting effect of the polyphenolic complex from plantago major (plantastine) on the carcinogenic effect of endogenously synthesized nitrosodimethylamine].amidopyrine administered in combination with sodium nitrite in the long-term experiment produces the toxic damage of the liver and tumors in rats in connection with endogenic synthesis of carcinogenic nitrosodimethylamine. the inclusion into the animal diet of the polyphenolic complex from plantago major--plantastine as an inhibitor of the carcinogen synthesis reduced the toxic damage of the liver that was indicated by normalization of biochemical parameters and also decreased the tumor yield fr ...19892806533
[uterotonic action of extracts from a group of medicinal plants].water extracts (infusions) from a group of medicinal plants were studied in terms of their activity enhancing the uterine tonus in a series of experiments with a preparation of an isolated rabbit and guinea pig uterine horn. in a final extract concentration of 1 to 2 mg crude drug per 1 cm3 the plants ranked in the following descending order with regard to their tonus-raising effect on the uterus: camomile (matricaria chamomilla l.), potmarigold calendula (calendula officinalis l.) cockscomb (ce ...19817314446
[sub-chronic toxicity and test of eye irritability of leaf aqueous extract from plantago major (plantaginaceae)].for the sub-chronic toxicity an aqueous preparation of plantago major leaves was tested in 20 male ngp mice, with an average weight of 20.15 g and separated in two groups of ten individuals each. the dose used was 2000 mg/kg and the control group received 0.5 ml of distilled water. the extract administration was done daily during five days at week for a total period of 40 days. signs of sub-chronic toxicity were observed in the days two and 12 of treatment. no significant change in corporal weig ...200315162770
in vitro cytotoxic, antiviral and immunomodulatory effects of plantago major and plantago asiatica.plantago major linn. and p. asiatica linn. (plantaginaceae) are commonly used as folk medicine in taiwan for treating infectious diseases related to the respiratory, urinary and digestive tracts. in this study, we investigated the antiviral, cytotoxic and immunomodulatory activities of hot water extracts of these two species in vitro on a series of viruses, namely herpesviruses (hsv-1 and hsv-2), adenoviruses (adv-3, adv-8 and adv-11), and on various human leukemia, lymphoma and carcinoma cells ...200312856861
in vivo antitumoral effect of plantago major l. extract on balb/c mouse with ehrlich ascites tumor.the aim of this study is to investigate the antitumor activity of plantago major l. extract in ehrlich ascites tumor (eat) bearing balb/c mice in vivo. thirty male balb/c mice were divided into 5 groups: 3 treatment groups and 2 control groups (6 per group). treatment groups and the negative control group were injected with eat (1 x 10(6) cells) intraperitoneally to develop ascites tumor. p. major l. extract (1%, 2% and 3% concentration extracts, 0.1 ml/day/mouse) were given p.o. for 10 alternat ...200717963323
protective effect of plantago major l. pectin polysaccharide against systemic streptococcus pneumoniae infection in mice.the antibacterial effect of a soluble pectin polysaccharide, pmii, isolated from the leaves of plantago major, was examined in inbred nih/olahsd and fox chase scid mice experimentally infected with streptococcus pneumoniae serotype 6b. serotype 6b is known to give a more protracted infection when injected intraperitoneally into susceptible mice than more virulent serotypes like type 4. pmii was administered i.p. either once 3 days before challenge or once to thrice from 3 to 48 h after challenge ...200011013005
a phloem-specific sucrose-h+ symporter from plantago major l. supports the model of apoplastic phloem loading.in this paper the cloning of a full-length cdna clone encoding the pmsuc2 sucrose-h+ symporter from plantago major is described. this plant allows the simple preparation of vascular bundles from the basal regions of fully developed source leaves and thus a separation of vascular and non-vascular tissue. a cdna library was constructed from poly(a)+ rna isolated from vascular bundles and used for the subsequent cloning of cdnas. the respective mrna is specifically expressed in the vascular bundles ...19948000426
differential expression of sucrose transporter and polyol transporter genes during maturation of common plantain companion cells.the cdnas of two sorbitol transporters, common plantain (plantago major) polyol transporter (plt) 1 and 2 (pmplt1 and pmplt2), were isolated from a vascular bundle-specific cdna library from common plantain, a dicot plant transporting suc plus sorbitol in its phloem. here, we describe the kinetic characterization of these sorbitol transporters by functional expression in brewer's yeast (saccharomyces cerevisiae) and in xenopus sp. oocytes and for the first time the localization of plant plts in ...200414630956
comparison of antimicrobial efficacy of triclosan- containing, herbal and homeopathy toothpastes- an invitro study.use of antimicrobial agents is one of the important strategies to prevent oral diseases. these agents vary in their abilities to deliver preventive and therapeutic benefits.201526557516
[the effect of extremely low doses of the novel regulatory plant proteins ].searching and study on regulatory proteins, which can keep under control the scope of important processes as like as cell adhesion, proliferation, differentiation and morphogenesis, is an actual aim of the current biochemistry. recently we have identified s-100 proteins in plants of following species: plantain (plantago major l.), aloe (aloe arborescens l.), and bilberry (vaccinum myrtillus l.). extraction and purification of s-100 proteins gotten from these plants were performed by the method w ...200312881977
[detection of viral infection pathogens in medicinal plants grown in ukraine].monitoring of viral infection on medicinal plant plantations is carried out. panax ginseng c.a. meyer, valeriana officinalis l., plantago major l. with symptoms of viral infection were revealed. viral nature of symptoms was proved with biotesting method. morphology and sizes of virus particles, detected in panax ginseng method. morphology and sizes of virus particles, detected in panax ginseng c.a. meyer, valeriana officinalis l., plantago major l., were determined with electron microscopy metho ...200919938607
comparison of diagnostic techniques for the detection and differentiation of cherry leaf roll virus strains for quarantine purposes.some strains of cherry leaf roll virus (clrv) are considered as quarantine pests in new zealand. clrv was detected in seven plant host species: actinidia chinensis, hydrangea macrophylla, malus domestica, plantago major, ribes rubrum, rubus idaeus and rumex sp. collected from new zealand between 2005 and 2012. biological, serological and molecular techniques were compared for the detection and differentiation of clrv isolates. the biological analysis revealed differences in symptomatology and di ...201627129669
[biodegradable polymer microparticles with entraped herbal extracts: preparation with supercritical carbon dioxide and use for tissue repair].biodegradable microparticles based on poly-d,l-lactide with entrapped mixture of herbal water-soluble extracts of plantago major and calendula officinalis were prepared. for preparation of these microparticles the previously developed method based on the usage of supercritical carbon dioxide (sc-co2) was proposed. microparticles were obtained by two techniques: 1) by preparing porous polymer monolith containing entrapped mixture of herbal extracts, which was then reduced to fine microparticles ( ...200920000125
gradual disintegration of the floral symmetry gene network is implicated in the evolution of a wind-pollination syndrome.angiosperms exhibit staggering diversity in floral form, and evolution of floral morphology is often correlated with changes in pollination syndrome. the showy, bilaterally symmetrical flowers of the model species antirrhinum majus (plantaginaceae) are highly specialized for bee pollination. in a. majus, cycloidea (cyc), dichotoma (dich), radialis (rad), and divaricata (div) specify the development of floral bilateral symmetry. however, it is unclear to what extent evolution of these genes has r ...201121282634
antifungal efficacy of three medicinal plants glycyrrhiza glabra, ficus religiosa, and plantago major against oral candida albicans: a comparative analysis.from ancient times, plants with medicinal values are being tested and used in the treatment of various infectious diseases.201627723643
effect of plantago major on cell proliferation in vitro.plantago major (plantaginaceae) is popularly used to treat tumors, infections and as a blood purifier. aqueous, methanol, chloroform and hexane extracts of the aerial parts (leaves and seeds) were added to cd(1) mice bone marrow and spleen cultures incubated at 37 degrees c for 72h, and also added to escherichia coli, bacillus subtilis and candida albicans cultures, while methanol extract dilutions were added to htc-15, ovcar, uiso and kb cell line cultures. doses of 0.4 and 0.2 mg/ml of aqueous ...200616226858
the effect of plantago major linnaeus on serum total sialic acid, lipid-acibound sialic d, some trace elements and minerals after administration of 7,12-dimethylbenz(a)anthracene in rats.the present study was designed to evaluate the effect of plantago major linnaeus (pm) extract on serum total sialic acid (tsa), lipid-bound sialic acid (lsa), some trace elements (copper (cu), zinc (zn) and iron) and mineral levels (magnesium, calcium and sodium) in wistar albino rat administrated 7,12-dimethylbenz(a)anthracene (dmba). rats were divided into three equal groups (n = 6). group i comprised the control group, group ii was treated with dmba (100 mg/kg, single dose) and group iii was ...201121996710
immunoenhancing properties of plantago major leaf extract.plantago major (pm), also known as plantain, is a weed found in temperate zones worldwide. pm leaves have been associated with various biological properties ranging from antiinflammatory, antimicrobial and antitumour to wound healing. however, its mechanism of action associated with boosting of the immune function remains to be elucidated. we found that endotoxin-free methanol extracts from pm leaves, at doses of 50, 100, 250, and 500 microg/ml, were associated with 4.4 +/- 1, 6 +/- 1, 12 +/- 0. ...200011113999
modulatory effects of several herbal extracts on avian peripheral blood cell immune responses.standardized ethanol extracts of allium sativum (garlic), glycyrrhiza glabra (licorice), plantago major (plantain) and hippophae rhamnoides (sea buckthorn) were assessed for their effects on cellular immunity in laying hens. birds (n = 25) had blood samples taken and both specific and non-specific immune cell responsiveness were evaluated by a leukocyte proliferation assay, carbon clearance test and srbc phagocytosis in monocyte-derived macrophage cultures. licorice and sea buckthorn (50 microg/ ...200616619362
hepatoprotective and anti-inflammatory activities of plantago major l.the aim of this study was to investigate anti-inflammatory and hepatoprotective activities of plantago major l. (pm).200920442819
influence of plantaginaceae species on e. coli k12 growth in vitro: possible relation to phytochemical properties.the data concerning the influence of plantaginaceae water extracts on bacterial growth are contradictory.201525330854
ethnoveterinary medicines used to treat endoparasites and stomach problems in pigs and pets in british columbia, canada.this paper documents the medicinal plants used to treat endoparasites and stomach problems in dogs, cats and pigs in british columbia, canada. ethnoveterinary data was collected over a 6-month period in 2003. the majority of the information on pets came from 2 naturopaths, 10 herbalists, 5 dog trainers, breeders and pet shop owners, 9 holistic veterinarians and 6 of 27 organic farmers. two pig farmers joined the study in the final stages. the following plants were used as anthelmintics: artemisi ...200717628343
intracellular maltose is sufficient to induce mal gene expression in saccharomyces cerevisiae.the presence of maltose induces m4l gene expression in saccharomyces cells, but little is known abouthow maltose is sensed. strains with all maltose permease genes deleted are unable to induce mal geneexpression. in this study, we examined the role of maltose permease in maltose sensing by substituting a heterologous transporter for the native maltose permease. pmsuc2 encodes a sucrose transporter from the dicot plant plantago major that exhibits no significant sequence homology to maltose perme ...200212455689
evaluation of healing wound and genotoxicity potentials from extracts hydroalcoholic of plantago major and siparuna guianensis.despite the large use of the plantago major and siparuna guianensis in traditional medicine, there are no studies demonstrating the effectiveness from extracts of these plants in the healing process by the present methodology. this study reported the effects and toxicity of the p. major and s. guianensis extracts in the wound healing compared with a commercial product used in brazil by macroscopic and microscopic analysis. following injury in cervical dorsal area of the mice, the extract from p. ...201223354396
interactive effects between diet and genotypes of host and pathogen define the severity of infection.host resistance and parasite virulence are influenced by multiple interacting factors in complex natural communities. yet, these interactive effects are seldom studied concurrently, resulting in poor understanding of host-pathogen-environment dynamics. here, we investigated how the level of opportunist pathogen virulence, strength of host immunity and the host condition manipulated via diet affect the survival of wood tiger moth parasemia plantaginis (arctidae). larvae from "low cuticular melani ...201223139892
pesticide residues in some herbs growing in agricultural areas in poland.the aim of this paper was to assess residue content of plant protection products in selected herbs: achillea millefolium l., cichorium intybus l., equisetum arvense l., polygonum persicaria l., plantago lanceolata l., and plantago major l. the study comprises herbs growing in their natural habitat, 1 and 10 m away from crop fields. the herbs, 30 plants of each species, were sampled during the flowering stage between 1 and 20 july 2014. pesticide residue content was measured with the quechers met ...201526612566
folk medicine in the northern coast of colombia: an overview.traditional remedies are an integral part of colombian culture. here we present the results of a three-year study of ethnopharmacology and folk-medicine use among the population of the atlantic coast of colombia, specifically in department of bolívar. we collected information related to different herbal medicinal uses of the local flora in the treatment of the most common human diseases and health disorders in the area, and determined the relative importance of the species surveyed.201121939522
in vitro effects of plantago major extract, aucubin, and baicalein on candida albicans biofilm formation, metabolic activity, and cell surface hydrophobicity.to determine the in vitro effectiveness of plantago major extract, along with two of its active components, aucubin and baicalein, on the inhibition of candida albicans growth, biofilm formation, metabolic activity, and cell surface hydrophobicity.201526618515
non-experimental validation of ethnoveterinary plants and indigenous knowledge used for backyard pigs and chickens in trinidad and tobago.this paper presents the findings of an exploratory study on ethnoveterinary medicines used for backyard pigs and backyard chickens in trinidad and tobago. research data was collected from 1995 to september 2000. six plants are used for backyard pigs. crushed leaves of immortelle (erythrina pallida, e. micropteryx) are used to remove dead piglets from the uterus. leaf decoctions of bois canôt (cecropia peltata) and bamboo (bambusa vulgaris) are used for labour pains or leaves are fed as a postpar ...200717944308
plantago major protective effects on antioxidant status after administration of 7,12-dimethylbenz(a)anthracene in rats.aim: the present study was designed to evaluate effects of plantago major extract on oxidative status in wistar albino rats administrated 7,12-dimethylbenz(a)anthracene (dmba). methods: rats were divided into three equal groups of 6 animals each: group 1 controls, group 2 treated with dmba (100 mg/kg, single dose) and group 3 receiving the dmba and the aqueous extract at 100 mg/kg/d for 60 days. results: significant decrease in catalase (p< 0.05), carbonic anhydrase (p≤0.01), reduced glutathione ...201121545225
use of plantago major seed mucilage as a novel edible coating incorporated with anethum graveolens essential oil on shelf life extension of beef in refrigerated storage.in this study, plantago major seed mucilage (pmsm) was extracted from whole seeds using hot-water extraction (hwe). the dill (d) essential oil components were identified through gas chromatography (gc) and gas chromatography/mass spectrometry (gc/ms) and its antioxidant properties were examined through the methods of 2,2-diphenyl-1-picrylhydrazyl (dpph), ferric reducing antioxidant potential (frap) and ß-carotene-linoleic acid assay (b-cl). total phenolic content (tpc) was characterized through ...201727771410
inhibitory activity of plantago major l. on angiotensin i-converting enzyme.eight compounds were isolated from methanol extract of plantago major l. leaves and investigated for their ability to inhibit angiotensin i-converting enzyme activity. among them, compound 1 showed the most potent inhibition with rate of 28.06 ± 0.21% at a concentration of 100 μm. compounds 2 and 8 exhibited weak activities. these results suggest that compound 1 might contribute to the ability of p. major to inhibit the activity of angiotensin i- converting enzyme.201121547673
within-population genetic diversity of taraxacum officinale (asteraceae): differential genotype response and effect on interspecific competition.clonal offspring of five morphologically distinct individuals of taraxacum officinale were planted in a greenhouse experiment with each of three competitors, plantago major, poa pratensis and trifolium pratense. the competitors were chosen to represent a series of competitive environments experienced by a natural population of t. officinale through the year. differences in size, morphology, and response to the competitive environments were found among clones and support classification of the fiv ...199821684978
review on medicinal uses, pharmacological, phytochemistry and immunomodulatory activity of plants.since ancient times, plants have been an exemplary source of medicine. researchers have discovered some important compounds from plants. the present work constitutes a review of the medicinal plants whose immunomodulant activity has been proven. we performed pubmed, embase, google scholar searches for research papers of medicinal plants having immunomodulant activity. medicinal plants used by traditional physicians or reported as having immunomodulant activity include acacia concocinna, camellia ...201725280022
an ethnobotanical survey of traditionally used plants on suva planina mountain (south-eastern serbia).this study documents the ethnobotanical and ethnomedicinal importance of plants in the suva planina mountain region (south-eastern serbia). it is reflected in their high diversity and their wide range of uses in the treatment of the local population. the aim of this study was a comparative analysis of data collected in the suva planina region with relevant data from the western balkans, which included identifying the 'most popular' plants, as well as those species which are used specifically for ...201526375774
anti-helicobacter pylori activity of plant extracts traditionally used for the treatment of gastrointestinal disorders.the antibacterial activity of plant extracts obtained from bixa orellana l., chamomilla recutita l., ilex paraguariensis a. st.-hil., malva sylvestris l., plantago major l. and rheum rhaponticum l. has been evaluated against two reference strains and eleven clinical isolates of helicobacter pylori. all the plant species chosen are used in popular brazilian cuisine and folk medicine in the treatment of gastrointestinal disorders. initial screening was made by the disk diffusion test and then mini ...201024031496
hydroxyl scavenging activity accounts for differential antioxidant protection of plantago major against oxidative toxicity in isolated rat liver mitochondria.the aim of this work was to study the effects of p. major against the oxidative damage of isolated rat liver mitochondria.201222775221
antiplasmodial activity of ethanolic extracts of some selected medicinal plants from the northwest of iran.the effectiveness of antimalarial drugs is declining at an ever accelerating rate, with consequent increase in malaria-related morbidity and mortality. the newest antiplasmodial drug from plants is needed to overcome this problem. the aim of this study was to assess antimalarial activity of the ethanolic extracts of 10 different medicinal plants from eight families against plasmodium falciparum chloroquine-sensitive 3d7 strain. the selection of the hereby studied plants was based on the existing ...201323922204
a survey of herbal weeds that are used to treat gastrointestinal disorders from southern thailand: krabi and songkhla provinces.weeds are plants grow naturally and are commonly seen. they are mostly used for feedstuff. however, their use as herbs for treating diseases, including gastrointestinal disorders, is rare. therefore, the present study aimed to: (1) quantify the number of herbal weeds used for treating gastrointestinal disorders; (2) study local knowledge of weed utilization for treating gastrointestinal disorders in songkhla and krabi provinces; and (3) analyse quantitative data with the informant consensus fact ...201727956357
common plantain. a collection of expressed sequence tags from vascular tissue and a simple and efficient transformation method.the vascular tissue of higher plants consists of specialized cells that differ from all other cells with respect to their shape and size, their organellar composition, their extracellular matrix, the type of their plasmodesmata, and their physiological functions. intact and pure vascular tissue can be isolated easily and rapidly from leaf blades of common plantain (plantago major), a plant that has been used repeatedly for molecular studies of phloem transport. here, we present a transcriptome a ...200617041024
maximum sustainable xylem sap tensions in rhododendron and other species.the acoustic technique was used in conjunction with the pressure chamber to determine the tensions causing cavitation of xylem sap in leaves of five woody angiosperms (acer pseudoplatanus l., alnus glutinosa l. gaertn., eucalyptus globulus labill., fraxinus excelsior l. and rhododendron ponticum l.) and three species of herbs (lycopersicum esculentum mill., plantago major l. and ricinus communis l.). the results showed leaves of most species to suffer considerably from cavitation at sap tensions ...198524249264
a review of the efficacy of traditional iranian medicine for inflammatory bowel disease.the etiology of inflammatory bowel disease (ibd) is not yet known, but many factors such as defects in the immune system, oxidative stress, microbial content in the gastrointestinal tract, nuclear factor (nf)-κb, nitric oxide (no), cyclooxygenase-2 (cox-2), and leukotriene b4 (lb4) are thought to play a role in its pathogenesis. in traditional iranian medicine (tim), several medicinal plants are thought to be effective for the treatment of ibd. in this study, information on all of these remedies ...201020857519
antimicrobial efficacy of three medicinal plants glycyrrhiza glabra, ficus religiosa, and plantago major on inhibiting primary plaque colonizers and periodontal pathogens: an in vitro study.from ancient times, plants with medicinal values are being tested and used in treatment of various infectious disease.201627237214
phloem-specific expression of yang cycle genes and identification of novel yang cycle enzymes in plantago and arabidopsis.the 5-methylthioadenosine (mta) or yang cycle is a set of reactions that recycle mta to met. in plants, mta is a byproduct of polyamine, ethylene, and nicotianamine biosynthesis. vascular transcriptome analyses revealed phloem-specific expression of the yang cycle gene 5-methylthioribose kinase1 (mtk1) in plantago major and arabidopsis thaliana. as arabidopsis has only a single mtk gene, we hypothesized that the expression of other yang cycle genes might also be vascular specific. reporter gene ...201121540433
characterization of the complete genome of ribgrass mosaic virus isolated from plantago major l. from new zealand and actinidia spp. from china.the complete genomes of tobamovirus isolates from plantago major l. from new zealand (nz-439), plantago sp. from germany (kons 1105), actinidia chinensis (actinidia-ac) and a. deliciosa (actinidia-ad) from china were sequenced and compared to previously published tobamovirus genomes. their genome organization and phylogenetic analysis of the putative replicase component, replicase readthrough component, movement protein, coat protein and complete genome placed all four isolates in subgroup 3 of ...201222456910
the investigation of antibacterial activity of selected native plants from north of iran.plant derived products have been used for medicinal purposes during centuries. bacterial resistance to currently used antibiotics has become a concern to public health. the development of bacterial super resistant strains has resulted in the currently used antibiotic agents failing to end many bacterial infections. for this reason, the search is ongoing for new antimicrobial agents, both by the design and by the synthesis of new agents, or through the search of natural sources for yet undiscover ...201528255395
hydrogen peroxide concentrations in leaves under natural conditions.while h2o2 has been implicated in numerous plant environmental responses, normal levels and variabilities are poorly established, and estimates of leaf tissue concentrations span more than three orders of magnitude, even in a single species under similar conditions. here, leaf tissue h2o2 contents under natural conditions are reported after determining (i) that h2o2 in extracts was stable with time, (ii) that h2o2 added to the extract was recovered quantitatively, and (iii) that the h2o2 calibra ...200616766599
protective effect of plantago major extract against t-booh-induced mitochondrial oxidative damage and cytotoxicity.plantago major l. produces several chemical substances with anti-inflammatory and analgesic activities and its use in the treatment of oral and throat inflammation in popular medicine is well described. in this study, the antioxidant potential of the plantago major hydroethanolic extract was screened and its protective action was evaluated against t-booh-induced oxidative stress. the extract was obtained by fractionated percolation using 50% ethanolic solution and, after drying, suspended in dim ...201526404215
subcellular concentrations of sugar alcohols and sugars in relation to phloem translocation in plantago major, plantago maritima, prunus persica, and apium graveolens.sugar and sugar alcohol concentrations were analyzed in subcellular compartments of mesophyll cells, in the apoplast, and in the phloem sap of leaves of plantago major (common plantain), plantago maritima (sea plantain), prunus persica (peach) and apium graveolens (celery). in addition to sucrose, common plantain, sea plantain, and peach also translocated substantial amounts of sorbitol, whereas celery translocated mannitol as well. sucrose was always present in vacuole and cytosol of mesophyll ...200818188589
analysis of arsenic and antimony distribution within plants growing at an old mine site in ouche (cantal, france) and identification of species suitable for site revegetation.one of the objectives of this study was to assess the contamination levels in the tailings of an old antimony mine site located in ouche (cantal, france). throughout the 1.3 ha site, homogenous concentrations of antimony and arsenic, a by-product of the operation, were found along 0-0.5 m-deep profiles. maximum concentrations for antimony and arsenic were 5780 mg kg(-1) dry tailings and 852 mg kg(-1) dry tailings, respectively. despite the presence of the contaminants and the low ph and organic ...201222789654
n-butanol fraction of entada phaseoloides ethanol extract inhibits hepatocellular carcinoma hepg2 cell proliferation by inducing apoptosis.to screen for substances with inhibitory effects on the proliferation of hepatocellular carcinoma (hcc) hepg2 cell line from extracts of traditional chinese medicinal plants including heliciopsis lobata (merr.) sleum, bidens pilosa, entada phaseoloides, plantago major, and smilax, and unveil their mechanism of action.201424965399
genotoxicity testing of plantago major extracts in somatic cells of drosophila melanogaster.plantago major is used in many parts of the world for the treatment of diseases and to promote the healing of wounds. in the present study, the somatic mutation and recombination test (smart) in drosophila melanogaster was used to evaluate the genotoxic activity of an aqueous extract of p. major. the following drosophila crosses were made: standard (st) cross, in which virgin flare females (flr3/tm3, bds) were mated with mwh/mwh males, and high-bioactivation (hb) cross, in which virgin orr femal ...200515612001
role of plant β-glucosidases in the dual defense system of iridoid glycosides and their hydrolyzing enzymes in plantago lanceolata and plantago major.the typical defense compounds of plantaginaceae are the iridoid glycosides, which retard growth and/or enhance mortality of non-adapted herbivores. in plants, glycosidic defense compounds and hydrolytic enzymes often form a dual defense system, in which the glycosides are activated by the enzymes to exert biological effects. yet, little is known about the activating enzymes in iridoid glycoside-containing plants. to examine the role of plant-derived β-glucosidases in the dual defense system of t ...201323773298
structural analysis of xyloglucans in the primary cell walls of plants in the subclass asteridae.the structures of xyloglucans from several plants in the subclass asteridae were examined to determine how their structures vary in different taxonomic orders. xyloglucans, solubilized from plant cell walls by a sequential (enzymatic and chemical) extraction procedure, were isolated, and their structures were characterized by nmr spectroscopy and mass spectrometry. all campanulids examined, including lactuca sativa (lettuce, order asterales), tenacetum ptarmiciflorum (dusty miller, order asteral ...200515975566
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