serum protein pattern of mice during infection with single and repeated doses of ancylostoma caninum larvae. | electrophoretic pattern of serum protein in mice during ancylostoma caninum larval infection with various single and repeated doses were observed to ascertain whether these changes take place according to their increase in dose levels. comparison between single and repeatedly infected groups were also made statistically. | 1975 | 51800 |
experimental infection with ancylostoma caninum larvae in mice. iv. serum protein pattern during primary infection. | serum protein of swiss albino mice infected with ancylostoma caninum larvae, were analysed electrophoretically. twenty mice were infected with a dose of 1000 larvae and the alterations in serum protein during an infection period of 30 days were recorded and compared with uninfected controls. the result showed a significant decrease in albumin and gamma globulin with an increase in beta globulin. there were no significant changes in the alpha-1 and alpha-2 globulins. the total globulins increased ... | 1976 | 67139 |
experimental infection with ancylostoma caninum larvae in mice. v. serum protein pattern during infection with various doses. | serum protein patterns of swiss albino mice during ancylostoma caninum infection with varying dose levels were studied electrophoretically. there was a significant decrease in albumin associated with a corresponding increase in beta globulin in all the infected groups. gamma globulin decreased significantly in all groups except the one infected with a challenge dose of 4000 larvae. maximum changes occurred on day 31, 15, 9, 15 and 6 when mice were infected with 250, 500, 1000, 2000 and 4000 larv ... | 1978 | 85675 |
experimental infection with ancylostoma caninum larvae in mice. vi. serum protein pattern use due to repeated exposures to infection. | three mice groups were infected with various repeated doses and other four groups with single doses of ancylostoma caninum larvae. serum samples collected at various intervals were analysed electrophoretically. the results were compared first with an uninfected control group and then with those of the corresponding non-immunized single-dose-infected groups. remarkably decreased values of albumin, increased beta globulin and increased total globulins with a decreased a/g ratio were observed. ther ... | 1979 | 93128 |
in vitro cultivation of ancylostoma duodenale and ancylostoma caninum. | | 1979 | 117988 |
anthelmintic efficacy of pyrantel pamoate against the roundworm, toxocara canis, and the hookworm, ancylostoma caninum, in dogs. | | 1978 | 250990 |
the response to phytohaemagglutinin of peripheral blood lymphocytes from dogs infected with ancylostoma caninum. | | 1977 | 275673 |
the efficacy of amidantel, a new anthelmintic, on hookworms and ascarids in dogs. | amidantel is a new anthelmintic from a new chemical class with an interesting anthelmintic spectrum. in dogs amidantel is highly effective in a single oral dose of 25 mg/kg against both hookworm species, ancylostoma caninum and unicinaria stenocephala. in toxascaris leonina infected dogs a complete cure rate was achieved with a single oral dose of 50 mg/kg. similar results were obtained with 8 mg/kg administered three times per day. the most sensitive parasite to amidantel was found to be toxoca ... | 1979 | 295548 |
anthelmintics. | this article describes the drugs used in helminthic infections and their therapeutic indications, mode of action, toxicity and other details of each of the recommended drugs, and discusses the nature and treatment of infection by helminths important in human medicine. infestation due to the roundworms enterobius vermicularis, ascaris lumbricoides and the hookworms, ancylostoma duodenale and necator americanus can all be treated effectively with pyrantel pamoate. for enterobius vermicularis, howe ... | 1977 | 319991 |
[1st finding of the ancylostoma braziliense nematode (gómez de faria, 1910) in canis familiaris in cuba]. | according to the results obtained by investigators who have been devoted up to date to the study of dog helminthiases in cuba dog ancylostomiasis is produced by ancylostoma caninum. now, ancylostoma braziliense (gómez de faria, 1910) has been found in two dogs from the havana province. the knowledge of the invasion extension as well as of the intensity of infestation should wait for the exhaustive study of the collected material. | 1978 | 358325 |
a comparative in vitro study of antibody binding to different stages of the hookworm ancylostoma caninum. | the indirect fluorescent antibody technique (ifat) and the indirect immuno peroxidase technique (iipt) have been applied to cryostat sections and intact stages of the hookworm species ancylostoma caninum with sera from infected dogs. especially the role of the body surface (= cuticle (cortex, matrix, basal layer) and hypodermis) in immunity was studied. using cryostat sections and dead intact stages as the antigen, specific antibody binding was demonstrated round the ovum membrane and the cuticl ... | 1978 | 358640 |
igg antibody binding to the outer surface of infective larvae of ancylostoma caninum. | applying the indirect fluorescent antibody technique to the infective stages of the hookworm ancylostoma caninum, it appeared that they do not show igg antibody binding when serum from dogs infected with a. caninum was used in the test (antiserum). however, inhibiting these stages metabolically with azide or with low temperatures, igg antibody binding to the outer surface was observed. when the inhibitory factors were removed, shedding of fluorescent substances was seen, which were obviously com ... | 1978 | 369167 |
studies on experimental ancylostomiasis: transfer of acquired immunity to ancylostoma caninum in mice through sensitized thymus and bone marrow cells. | an attempt has been made to transfer acquired immunity to ancylostoma caninum infective larvae from infected swiss albino female mice to nonimmune, isologous recipients of same sex, through immunized thymus and bone marrow cells. immunized cells from donors infected with a single high dose of 1000 larvae were found to be more immunocompetent than cells from donors infected with a single, but low dose of 500 larvae. | 1979 | 385336 |
studies on endoparasites of the black bear (ursus americanus) in the southeastern united states. | examination of 53 black bears (ursus americanus) from six states in the southeastern united states revealed at least 17 species of endoparasites, including sarcocystis sp., spirometra mansonoides (spargana), macracanthorhynchus ingens, ancylostoma caninum, arthrocephalus lotoris, baylisascaris transfuga, capillaria aerophila, capillaria putorii, crenosoma sp., cyathospirura sp., dirofilaria immitis, gnathostoma sp., gongylonema pulchrum, microfilariae, molineus barbatus, physaloptera sp. and str ... | 1978 | 418189 |
parasites of the coyote (canis latrans) in central utah. | seventeen coyotes, canis latrans, from central utah were surveyed for parasites. five species of parasites not reported previously from coyotes in utah were detected: filaroides osleri, physaloptera sp., spirocerca sp., ancylostoma caninum, and cediopsylla simplex. in all, 11 genera of parasites were observed. | 1978 | 418190 |
a survey of gastro intestinal helminth parasites of stray dogs in zaria, nigeria. | a survey of helminth parasites in stray dogs was carried out in the zaria area. out of 180 dogs examined 65.6 per cent (118/180) were found positive for ancylostoma caninum, while toxocara canis and trichuris vulpis were detected in 41.1 per cent (74/180) and 13.9 per cent (25/180) respectively. other helminth parasites found taenia ovis 35 per cent (63/180) taenia hydatigena 67.8 per cent (122/180), echinococcus granulosus 0.006 per cent (1/180) and dipylidium caninum 97.8 per cent (176/180). | 1979 | 452351 |
intestinal mast cells during experimental ancylostomiasis. | the alterations of mast cell counts induced in the gut of swiss albino mice by infection with ancylostoma caninum larvae have been studied, both in single and multiple infections. it was found that mast cell rise was greater in females than males. in singly infected animals, mast cell increase was influenced by the infective dose of inoculated larvae. in case of repeatedly infected mice, mast cell counts were decreased because of their earlier degranulation. | 1979 | 458129 |
avermectins, new family of potent anthelmintic agents: efficacy of the b1a component. | when given to sheep as a single oral dose at 0.1 mg/kg, the b(1a) component of the avermectins caused a reduction of >95% in the numbers of haemonchus contortus, ostertagia circumcincta (including inhibited l(4) larvae), trichostrongylus axei, trichostrongylus colubriformis, cooperia oncophora, and oesophagostomum columbianum. when given to cattle as a single oral dose at 0.1 mg/kg, avermectin b(1a) was >95% effective in reducing the numbers of haemonchus placei, ostertagia ostertagi (including ... | 1979 | 464563 |
longevity and infectivity of somatic larvae of ancylostoma caninum in guinea and swine. | | 1979 | 480079 |
effect of worm burden on female to male ratio and epg in parasitism by ancylostoma caninum. | | 1979 | 482770 |
use of fenbendazole suspension (10%) against experimental infections of toxocara canis and ancylostoma caninum in beagle pups. | eleven nematode-free beagle pups were inoculated with ancylostoma caninum and toxocara canis; infection became patent 13 and 35 days later, respectively. eight pups were treated with fenbendazole oral suspension (10%) at a dosage of 50 mg/kg of body weight/day for 3 days. the remaining three animals were unmedicated controls. the drug was effective in reducing both ascarid and hookworm burdens, and there was marked improvement in the clinical condition of treated pups as compared with unmedicate ... | 1979 | 517828 |
haemagglutination test in mice infected with ancylostoma caninum larvae. | | 1979 | 541495 |
[localization of adult ancylostoma caninum in the intestines of dogs with experimental ancylostomiasis]. | | 1977 | 553473 |
[galactogenic transmission of third larvae of ancylostoma caninum ercolani 1859 (ancylostomidae) in paratenic hosts]. | | 1978 | 569954 |
pharmacological estimation of histamine in the intestine of mice experimentally infected with single doses of ancylostoma caninum larvae. | histamine content of the intestine of young female swiss albino mice experimentally infected per os with low (500) and high (2000) doses of ancylostoma caninum larvae was studied. the histamine level increased in both the experimental groups reaching peak values on the 16th day post infection in animals inoculated with a dose of 500 larvae and on the 30th day post infection in animals inoculated with 2000 larvae; the histamine content was 2.5 times higher in the former and 4 times higher in the ... | 1979 | 575901 |
gastro-intestinal helminths of domestic dogs in the republic of south africa. | of the gastro-intestinal helminths found in 1 063 dogs from different parts of the country, dipylidium caninum, the most prevalent cestode, occurred in 19,7% of the animals. echinococcus granulosus was present in 10 dogs, 8 of which were from urban areas, and taenia hydatigena in 69 dogs. taemia multiceps was recovered from dogs only in the cape province and the orange free state. toxocara canis was present in 81 of the necropsies carried out on 253 dogs from the pretoria municipal area, while a ... | 1979 | 575920 |
[a case of relapsing cutaneous larva migrans transmitted by a cheetah (acinonyx jubatus)]. | a case of relapsing "creeping eruption" connected with parasites of the cheetah is reported in the man. the parasitological examination, carried out in two cheetahs liable of this syndrome, has shown two different helmintic species: ancylostoma caninum and ancylostoma tubaeforme. | 1978 | 575999 |
on the phospholipids of adult ancylostoma caninum. | the phospholipid composition of ancylostoma caninum has been examined. phospholipids amounted to 0.9% of the wet weight of the parasite. ethanolamine and choline containing lipids comprised about 76% of the total phospholipids. lysolecithin, sphingomyelin, phosphatidyl inositol and phosphatidyl serine were present in minor amounts. cerebrosides and sulfatides were also identified. | 1977 | 590444 |
spinal nematodiasis of the dog associated with ancylostoma caninum. | | 1977 | 614029 |
gastrointestinal parasitism of iowa coyotes in relation to age. | taenia sp., physaloptera sp., ancylostoma caninum, toxascaris leonina, and/or trichuris vulpis were recovered from gastrointestinal tracts of 141 and 144 (97.9%) coyotes ranging from 1/2 to 8 1/2 years of age. ancylostoma caninum exhibited a significant decline in both prevalence and mean number per coyote with increasing age of the host. taenia sp. appeared with consistently high prevalence in all age classes. physaloptera sp. and t. leonina showed general reductions in prevalence in all age cl ... | 1978 | 641673 |
the distribution of ancylostoma caninum larvae in the central nervous system of the mouse infected with single or repeated doses. | the distribution of ancylostoma caninum larvae in the various regions of the central nervous system of mice of previously uninfected or reinfected groups was studied. although a dose of 4000 larvae was lethal, the distribution of larvae was not appreciable in the cns. many larvae were recovered from the cerebral hemispheres and cerebellum of infected mice whereas no incidence of eye involvement was observed in any mouse. in the reinfected mice groups there was a much lower recovery than in the p ... | 1978 | 670667 |
gastrointestinal helminths in dogs from a humane shelter in indiana. | between january 1975 and august 1976, the alimentary tracts of 104 euthanatized dogs from a humane shelter in tippecanoe county, indiana, were examined to determine the prevalence of gastrointestinal helminths. the survey was restricted to dogs greater than 1 year old. their average age was estimated at approximately 2 years. parasitism was detected in 86.5% of the dogs examined. ancylostoma caninum was found most often (58.7%), followed by trichuris vulpis (51.9%), taenia sp (31.7%), toxocara c ... | 1978 | 721684 |
experimental infection of ancylostoma caninum in mice. iii. distribution of larvae after repeated exposures to infection. | different groups of mice were infected with various single or repeated doses of larvae of ancylostoma caninum. considerable loss of larvae occurred in the immunised groups when compared with their counterpart unimmunised groups. larval migration and distribution in the different tissues was less in immunised mice, as most larvae were expelled from the gastrointestinal tract. this resulted in a poor onward larval migration to liver, lungs, brain and muscle regions in immunised groups. the heavily ... | 1978 | 722039 |
the efficacy of anthelmintics against third stage larvae of ancylostoma caninum in mastomys natalensis. | investigations have been carried out on the multimammate rat (mastomys natalensis), orally infected with 1000 third stage larvae of ancylostoma caninum per animal, to evaluate the larvicidal efficacy of anthelmintics in this paratenic host. the oral or subcutaneous administration of 19 anthelmintics and filaricides revealed good activity for levamisole, cambendazole, and mebendazole against 15-day-old ancylostoma larvae which were located in the muscular tissue. similarly, good results were obta ... | 1978 | 741857 |
efficacy of avermectins against ancylostoma caninum in dogs. | | 1978 | 752053 |
[research on intestinal parasitic diseases in dogs of the city of rome]. | a survey on the diffusion of intestinal parasites of dogs in the town of rome. the results of a survey on the diffusion of cestodes and nematodes in a hundred dogs in rome are reported. the dogs were subjected to fecal examinations --- using both the flottation method and the mcmaster method -- and to the post-mortem examination of the intestine. at post-mortem examination 25 dogs were found parasitized by one or more species of nematodes, 19 by one or more species of cestodes and 12 both by ces ... | 1977 | 754133 |
intracellular (muscle-fiber) habitat of ancylostoma caninum in some mammalian hosts. | the persistence and precise location of ancylostoma caninum larvae in tissues of vertebrate paratenic hosts and the nature of host responses were studied in mouse, cat, and monkey. mice were infected percutaneously and examined at various intervals up to 260 days after exposure. long-persisting larvae were found only in the muscles. histologic sections revealed that within 4 hr after exposure some larvae had migrated through the skin and had entered individual fibers of the underlying muscles. a ... | 1975 | 809563 |
experimental cross-breeding of ancylostoma tubaeforme (zeder, 1800) and ancylostoma caninum (ercolani, 1859). | in experimental crosses between a. tubaeform and a caninum the worms failed to produce progeny in dual-strain combinations. even though these two strains did not fail to copulate. egg production was observed only in identical single-strain combinations. this supports the assumption that the two species are genetically separate and valid. | 1977 | 918711 |
skin penetration of infective hookworm larvae. iii. comparative studies on the path of migration of the hookworms ancylostoma braziliense, ancylostoma ceylanicum, and ancylostoma caninum. | the lateral skin areas of nine hookworm-free puppies were exposed to infective larvae of ancylostoma braziliense, ancylostoma ceylanicum and ancylostoma caninum. serial sections, stained with harris' haematoxylin and eosin, showed that many similarities exist in the migration patterns of the hookworm species used. however, striking differences were observed between ancylostoma braziliense on the one hand and ancylostoma ceylanicum and ancylostoma caninum on the other hand with regard to the spee ... | 1977 | 919694 |
anthelmintic activity of diuredosan in dogs experimentally infected with ancylostoma caninum and trichuris vulpis. | the efficacy of diuredosan was determined in dogs experimentally infected with ancylostoma caninum and trichuris vulpis. diuredosan at dosages of 25, 50, and 100 mg/kg was 99% effective against a caninum. efficacies against t vulpis were 88, 85, and 94% at dosages of 25, 50, and 100 mg/kg, respectively. | 1976 | 984564 |
helminth parasites of the fox (vulpes vulpes) in new south wales. | a total of 930 foxes (vulpes vulpes) from new south wales were examined for the presence of gastro-intestinal helminth parasites. the cestodes were represented by taenia pisiformis with a prevalence of 15.7%, t. serialis (22.6%), t. taeniaeformis (0.1%), spirometra erinacei (28.7%) and dipylidium caninum (8.3%). no specimens of t. ovis, t. hydatigena or echinococcus granulosus were encountered. toxocara canis was the most prevalent nematode and occurred in 35.2% of foxes. other nematodes encount ... | 1976 | 985241 |
infectivity of ancylostoma caninum larvae after freezing over liquid nitrogen. | third-stage larvae of ancyclostoma caninum were exsheathed either by carbon dioxide or sodium hypochlorite treatment. exsheathment per se reduced the infectivity of third-stage larvae by 45% to 59% without affecting larval motility. both ensheathed and exsheathed larvae were frozen over liquid nitrogen for 90 days, and thawed. frozen ensheathed larvae were all killed; but frozen exsheathed larvae were 40-54% as infective as non-frozen exsheathed larvae, and the addition of 10% dimethyl sulphoxid ... | 1976 | 985243 |
changes in hookworm distribution in surinam. | during the months may-july, 1974, a follow-up investigation was carried out on hookworm infections in dogs and cats in order to study changes in the hookworm distribution in surinam since 1967. fifty-two cats and 152 dogs were examined for the presence of helminths in the oesophagus, small intestine, coecum and heart. in total 15,942 helminths were isolated; most of these (14,006) were hookworms belonging to the species ancylostoma caninum, a. tubaeforme, a. ceylanicum and a. braziliense. the av ... | 1976 | 987625 |
the role of the house fly (musca domestica) in the dissemination of hookworm. | eggs and larvae of ancylostoma caninum were recovered from the crop, mid-gut and hind-gut of musca domestica; only larvae were recovered from the vomitus and one dead infective larva was recovered from the faeces on one occasion. all eggs recovered from the gut hatched after incubation for 48 hours. up to 319 eggs and 1485 larvae were recovered from the legs of experimentally contaminated flies. the viability of the eggs and the longevity of the larvae recovered from the gut and external surface ... | 1976 | 999359 |
[reactivation of inhibited larvae of ancylostoma caninum. effect of estradiol and progesterone]. | | 1976 | 1015057 |
prevalence and zoonotic potential of ancylostoma ceylanicum in cats in thailand. | ancylostoma ceylanicum and ancylostoma caninum were found in cats from prachin buri, thailand, with infection rates of 92% and 23%, respectively. in this survey, 75% of cats were infected with a. ceylanicum alone, the rest had mixed infections of a. ceylanicum and a. caninum. the worm burden range in 26 cats for a. ceylanicum and a. caninum were 1 to 83 and 1 to 10, respectively. for a. ceylanicum, both males and females were found in the gut from the first part of duodenum to rectum. in the cas ... | 1976 | 1030851 |
[evaluation of the disinfectant action of metepa on infected larvae of ancylostoma caninum. i. in-vitro studies]. | | 1976 | 1032475 |
uredofos: anthelmintic activity against nematodes and cestodes in dogs with naturally occurring infections. | a new broad-spectrum anthelmintic, uredofos, was tested in 146 dogs by single and multiple oral dosing. single doses of 100 and 50 (but not 25) mg/kg were totally effective in removing dipylidium caninum and taenia spp from 46 dogs with infections of tapeworms. among groups of 15 to 20 dogs, the average percentage efficacies against toxocara canis for single soese of 100, 50, and 25 mg/kg were 98, 96, and 81%, respectively. the average percentage of efficacies against hookworm (ancylostoma canin ... | 1976 | 1033721 |
letter: arrested development of larval ancylostoma caninum in the gastro-intestinal tract. | | 1976 | 1065821 |
survival of ancylostoma caninum on bluegrass pasture. | the survival of infective larvae of ancylostoma caninum on outdoor grass plots was studied in 40 experiments over 1 year. weather data were collected over the period. mean larval survival from august to early november was 24 days (range 1 to 49), from december through february was 0 days, and from march to mid-august was 6.6 days (range 0 to 21). moderate to high temperatures and substantial rainfall favored larval survival; low temperatures and rainfall favored larval destruction. | 1975 | 1138040 |
estimation of blood loss caused by ancylostoma caninum in dogs using 51-cr-labelled red cells. | | 1975 | 1145238 |
experimental infection of ancylostoma caninum in mice. ii. migration and distribution of larvae in tissues after oral infection. | | 1975 | 1184945 |
survival of ancylostoma caninum on bare ground, pea gravel, and concrete. | studies were done to determine the survival of infective ancylostoma caninum 3rd-stage larvae on 3 ground covers commonly used in dog run construction: bare ground, pea gravel, and concrete. changes in numbers of recovered larvae were compared to meterologic data and the most significant weather variables were determined. larvae were recovered 1 to 7 days on bare ground. larvae survived longer in the fecal mass (mean of 3 days) than on the bare ground (mean of 2 days). rain was the most signific ... | 1975 | 1200451 |
[pathology of experimental ancylostomiasis in dogs (ancylostoma caninum) studied with radioisotopes. i. blood volume (risa l 131). comparative study with human ancylostomiasis]. | | 1975 | 1235041 |
[pathology of experimental ancylostomiasis in dogs (ancylostoma caninum) studied by radioisotopes. 3. loss of intestinal proteins (pvp i 131). comparative study with human ancylostomiasis]. | | 1975 | 1235043 |
[effect of innoculation of dogs with ancylostoma caninum larvae irradiated with co 60]. | | 1975 | 1235044 |
intestinal helminths in dogs and cats on the antillian islands aruba, curaçao and bonaire. | an investigation into the prevalence, identity and size of population of intestinal helminths in dogs and cats was carried out in the dutch antillian islands, curaçao, bonaire and aruba during april and may 1974. ninety-one dogs and 83 cats were examined. in all, 4,824 helminths were isolated and identified. the following species were isolated from dogs: dipylidium caninum (most frequent), ancylostoma caninum (frequent in curaçao), toxocara, taenia hydatigena and ancylostoma braziliense. species ... | 1975 | 1237955 |
an investigation of helminth parasites in well-cared for dogs in accra. | a survey of a relative prevalence of helminth parasites in pet dogs has been conducted in the accra metropolitan area. carcass examination revealed a high incidence of ancylostoma caninum (58%), toxocara canis (40%), dipylidium caninum (24%), spirocerca lupi (18%) and a low 2% of taenia pisiformis. stool examination revealed hookworm ova in approximately 39% stools, ascarid ova in 4%, tapeworm in 1.3% and spirocerca in 0.24; a low incidence of strongloides (0.03) and trichurid ova (0.1%) were al ... | 1975 | 1241960 |
[chemotherapeutic effects of nitro compounds. 1. nitroanilines]. | more than 200 nitro compounds, most of them nitroaniline derivatives substituted with one or more radicals having a basic reaction, were prepared and investigated as to their therapeutic activity against bacteria, fungi, protozoa, helminths, viruses and tumors. several mono-nitrobenzenes with a radical having a basic reaction showed weak in-vitro activity against gram-positive bacteria and against crocker's sarcoma 180; they also showed systemic activity against nematodes (aspiculuris tetraptera ... | 1975 | 1242309 |
detection of antibodies to secretions of ancylostoma caninum in human eosinophilic enteritis. | to evaluate the role of canine hookworms in human eosinophilic enteritis (ee) in north-eastern australia, we tested human sera in an enzyme-linked immunosorbent assay (elisa) which incorporated antigens of adult ancylostoma caninum. sera from the following groups were examined: 10 patients with ee (unexplained recurrent abdominal pain and related symptoms, with peripheral eosinophilia) from townsville and brisbane; 2 persons known to be infected with a. caninum and 20 presumed unexposed healthy ... | 1992 | 1287934 |
[detection of intestinal parasites from dogs in tochigi-city in 1979 and 1991]. | to clarify whether sanitary and hygienic conditions surrounding humans and pet animals have improved or not, we examined feces from dogs for intestinal parasites in tochigi in 1979 and 1991. intestinal parasites were detected from 109 of the 262 dogs (41.9%) in 1979 and 86 of the 260 dogs (32.8%) in 1991. among the parasites. ancylostoma caninum, tirchuris vulpis and toxocara canis were most commonly detected, and their detection rates were higher in 1979. on the contrary, dipylidium caninum, st ... | 1992 | 1293225 |
weight loss, total and differential leucocytic counts in mice treated with alcohol during ancylostoma caninum infection. | females of swiss albino mice were treated with various doses of alcohol and ancylostoma caninum larvae. mice which received 40% alcohol for 20 days showed a significant decrease in body weight and in the number of leucocytes. eosinophilia was also observed in mice which were treated with 40% alcohol for 20 days. | 1992 | 1300354 |
[study on toxicology of a new anthelmintic "85012"]. | "85012", a new anthelmintic containing amidine synthesized in our laboratory, was experimentally effective against nippostrongylus braziliensis and ancylostoma caninum. in acute and subacute toxicity test, it was proved lowly toxic. there was no evidence that the drug induced any damages to main organs and tissues of animals. in order to evaluate its potential mutagenicity and teratogenicity, micronucleus test, bone marrow metaphase analysis, chl cells chromosomal aberration assay, spermatic abe ... | 1992 | 1394887 |
[extent and course of excretion of larva in the milk of female dogs after infections of different severity with ancylostoma caninum (ancylostomatidae)]. | it was investigated whether there is a linear correlation between the number of applied infective larvae of ancylostoma caninum and the number of larvae excreted by bitches with the milk. the investigations were carried out with nine bitches that were infected percutaneously each with 5,000, 10,000 or 20,000 third stage larvae of ancylostoma caninum at the day of conception. a clear linear correlation between the number of applied infective larvae of ancylostoma caninum and the number of larvae ... | 1992 | 1416220 |
[biology, pathogenicity, diagnosis and control of ancylostoma caninum]. | infections with ancylostoma caninum are transmitted orally or percutaneously. the transmission of infectious stages with the milk of particular importance for the distribution of the species. it occurs during the dissemination of larvae that follows every infection as well as after reactivation of resting somatic larvae in the bitch at the end of the pregnancy. the galactogenic transmission of larvae occurs even when, due to existing immunity, no patent infections develop in the bitch. immunity ... | 1992 | 1425324 |
efficacy of milbemycin oxime against experimentally induced ancylostoma caninum and uncinaria stenocephala infections in dogs. | twenty-eight helminth-naive beagles, 16 to 26 weeks old, were inoculated with 200 third-stage larvae each of ancylostoma caninum and uncinaria stenocephala 5 times at weekly intervals. dogs were randomly allocated to 4 groups of 7 on the basis of fecal egg counts, and treatments were randomly assigned. groups 1 and 3 were given milbemycin oxime at a dosage of 500 micrograms/kg of body weight, po, on day 0 and on days 0 and 30, respectively; groups 2 and 4 were nontreated controls. fecal egg coun ... | 1992 | 1429184 |
[the helminth fauna of the red fox (vulpes vulpes linne, 1758) in nordhessen and ostwestfalen. 2. nematodes]. | between november 1989 and june 1990 a total number of 397 foxes were examined for the presence of nematodes in the stomach and the small intestine and 403 foxes for the presence of trichinella spiralis larvae. the animals came from the districts of kassel, arnsberg and detmold. in 32.7% of the foxes infections with toxocara canis were found, in 11.1% toxascaris leonina, in 3.8% ancylostoma caninum, in 3.5% uncinaria stenocephala and in 2.3% capillaria species. in most cases the number of nematod ... | 1992 | 1459030 |
resumption of feeding in vitro by hookworm third-stage larvae: a comparative study. | third-stage infective larvae of the canine hookworm ancylostoma caninum resume feeding in vitro in response to several stimuli. experiments were conducted to characterize the in vitro feeding behavior of several hookworm species. reduced glutathione and, to a lesser extent, canine and human serum stimulated third-stage larvae of ancylostoma duodenale to resume feeding. glutathione-induced feeding reached a maximum by 16 hr and was concentration-dependent between 0- and 15-mm glutathione. oxidize ... | 1992 | 1491295 |
efficacy of an ivermectin/pyrantel pamoate chewable formulation against the canine hookworms, uncinaria stenocephala and ancylostoma caninum. | the effectiveness of the combination of pyrantel pamoate (5 mg kg-1) and ivermectin (6 micrograms kg-1) against the canine hookworms uncinaria stenocephala and ancylostoma caninum was determined. this combination is intended for monthly use as a heartworm preventative and for treatment and control of canine hookworms. the formulation was found to be effective (99.6% reduction in worm burdens) against both species of hookworms in experimentally infected dogs. no adverse effects due to the drug co ... | 1992 | 1532872 |
comparison of febantel tablets and vercom paste against gastrointestinal nematodes of dogs. | thirty adult dogs with naturally acquired gastrointestinal nematode infections were assigned at random to ten replicates and treated daily for 3 days with either a combination febantel/praziquantel (vercom) paste, febantel tablets or placebo tablets. numbers of hookworm and whipworm eggs after treatment were reduced similarly for both drug formulations when compared with pretreatment egg counts, whereas these counts increased in the controls. vercom paste reduced the hookworm egg count by 99.9% ... | 1992 | 1561756 |
efficacy of ivermectin and pyrantel pamoate combined in a chewable formulation against heartworm, hookworm, and ascarid infections in dogs. | eight trials were conducted in dogs to document the efficacy of ivermectin (6 micrograms/kg of body weight) and pyrantel pamoate (5 mg of active pyrantel/kg) in a beef-based chewable formulation against dirofilaria immitis, ancylostoma caninum, uncinaria stenocephala, toxocara canis, and toxascaris leonina. three studies involved induced infection with d immitis, and 5 studies involved induced or natural infection with hookworms and ascarids. in 3 intestinal parasite trials, the efficacy of the ... | 1992 | 1586021 |
ancylostoma caninum: reduced glutathione stimulates feeding by third-stage infective larvae. | the resumption of feeding in vitro has been proposed as an indicator of the reactivation of development by arrested third-stage hookworm larvae. the tripeptide glutathione was tested for its ability to induce in vitro feeding by third-stage infective larvae of the canine hookworm ancylostoma caninum. reduced glutathione, but not oxidized glutathione, stimulated larval feeding in a specific, concentration-dependent manner. feeding began at 5-10 mm, and reached a plateau at 25-50 mm. incubation in ... | 1992 | 1639163 |
albumin and a dialyzable serum factor stimulate feeding in vitro by third-stage larvae of the canine hookworm ancylostoma caninum. | previous studies demonstrated that third-stage, developmentally arrested larvae of the canine hookworm ancylostoma caninum resume feeding in vitro in response to canine serum and hostlike temperature. experiments to determine the identity of the serum stimulus are described. serum from several nonhost species stimulated feeding, but to levels lower than canine serum. heating the serum to 57 c had no effect on its stimulatory ability. dialysis reduced serum stimulatory activity by 50%, and ultraf ... | 1991 | 1713962 |
identification of dirofilaria immitis-infected dogs with a coagglutination assay. | the presence of dirofilaria immitis excretory-secretory (es) products was detected in the urine of infected dogs using a coagglutination assay. urine samples from 30 naturally infected dogs were positive. seventeen of them were microfilaremic, whereas 13 had become amicrofilaremic after receiving 2 courses of diethylcarbamazine. urine samples from 20 dogs infected with other parasites, dipetalonema reconditum (7), toxocara canis (5), and ancylostoma caninum (8), and urine samples from 20 healthy ... | 1992 | 1738064 |
evaluation of a beef-based chewable formulation of pyrantel pamoate against induced and natural infections of hookworms and ascarids in dogs. | pyrantel pamoate, formulated in a beef-based chewable tablet, was evaluated for efficacy in dogs against induced and natural infections of toxocara canis, toxascaris leonina, ancylostoma caninum and uncinaria stenocephala. dose titration trials were conducted in canada, the uk and germany in dogs treated with pyrantel (as pamoate salt) at 0, 2.5, 5 or 10 mg kg-1 body weight. these studies showed that a dose rate of 2.5 mg kg-1, the efficacy of pyrantel against adult t. canis, t. leonina, u. sten ... | 1991 | 1763481 |
anthelmintic activity of paraherquamide in dogs. | paraherquamide, an oxindole alkaloid metabolite of penicillium paraherquei and penicillium charlesii, was tested against the common gastrointestinal nematodes of dogs at a single oral dosage of 0.5, 1.0, or 2.0 mg kg-1. efficacy was poor (less than 85%) against ancylostoma caninum, uncinaria stenocephala, toxascaris leonina, trichuris vulpis, and strongyloides stercoralis at the low- and mid-dosage levels. at the high dosage level, good efficacy (91%) was observed only against s. stercoralis. ad ... | 1991 | 1788941 |
effects of alcohol on natural resistance to ancylostoma caninum in mice. | experiments were performed to study the effect of alcohol on natural immunity of swiss albino mice during ancylostoma caninum infection. natural resistance is lowered in alcoholic mice; 40% alcohol by mouth produced significant effect after 20 daily injections. the effect of the drug on natural immunity depended upon the concentration and the period of consumption. animals retained maximum number of larvae during alcohol treatment. | 1991 | 1804867 |
[parasitologic, clinical, hematologic and serologic findings in puppies after lactogenic infection with ancylostoma caninum ercolani 1859 (ancylostomidae)]. | the correlation between intensity of ancylostoma caninum infections in bitches and the intensity of lactogenic infections and clinical signs of their puppies was investigated. on average, 825, 1,867 or 2,125 specimens were observed in litters of two bitches inoculated with 5,000, 10,000 or 20,000 third stage larvae (liii) respectively, at the day of conception. adverse effects of the infection on the growth and behaviour of the puppies were observed after onset of their second week of life: 11/2 ... | 1991 | 1853668 |
effect of milbemycin oxime against ancylostoma caninum in dogs with naturally acquired infection. | twenty-six mixed-breed (14 males, 12 females) dogs were used in a double-blind study to evaluate the effect of milbemycin oxime against naturally acquired infection with ancylostoma caninum. dogs were ranked and paired, on the basis of number of hookworm eggs/g of feces, and treatment was randomly assigned. each dog was given either the study drug or placebo (1 tablet/11.4 kg [0.5 mg/kg] of body weight). eggs per gram of feces enumeration was done on days 3 and 7 after treatment, and dogs were e ... | 1991 | 1883101 |
host-finding and host recognition of infective ancylostoma caninum larvae. | a. caninum larvae responded to environmental and host stimuli with four behavioral phases of host-finding. (1) snake-like movement was stimulated by warmth and by defined vibrations of the substratum. (2) waving behavior was a prerequisite for the passive change-over to dog hairs. it was stimulated by heat radiation and by the co2 content, warmth, and humidity of an air stream. (3) creeping direction: the larvae were attracted by heat in temperature gradients as weak as 0.04 degrees c mm-1 and b ... | 1991 | 1917283 |
transaminases changes and worm burden in multiple infection of ancylostoma caninum in mice. | aspartate transaminase level was significantly increased in intestine of experimentals that received multiple doses of infection. the level of alanine transaminase rose to a significant value in liver of mice infected with multiple doses. rise of transaminases is correlated with the necrosis (disruption of intestina) hepatic cells in infected mice. changes and/or the distribution of aspartate transaminase and alanine transaminase with regard to the dosage is discussed. | 1991 | 1940329 |
human eosinophilic enteritis caused by dog hookworm ancylostoma caninum. | an epidemic of eosinophilic enteritis (93 cases) has occurred in townsville, northern queensland, australia. a hookworm was found attached to a resected, inflamed ileal segment from 1 patient but the species could not be identified. an adult hookworm of species ancylostoma caninum was recovered at colonoscopy from the terminal ileum of a later patient. all of 38 patients interviewed in an epidemiological survey described behaviour which could have exposed them to infective larvae of this widespr ... | 1990 | 1971376 |
hookworm folliculitis. | a case of persistent folliculitis in a 21-year-old man was demonstrated to be due to ancylostoma caninum larvae. treatment with oral thiabendazole was curative. cutaneous larva migrans may be due to a caninum, but this presentation appears to be unique. the literature concerning etiology and pathogenesis of larva migrans is discussed with reference to this case. | 1991 | 2006880 |
zinc sulfide in intestinal cell granules of ancylostoma caninum adults. | a source of confusion has existed since the turn of the century about the reddish brown, weakly birefringent "sphaerocrystals" located in the intestines of strongyle nematodes, strongylus and ancylostoma. x-ray diffraction and energy dispersive spectrometric analyses were used for accurate determination of the crystalline order and elemental composition of the granules in the canine hookworm ancylostoma caninum. the composition of the intestinal pigmented granules was identified unequivocally as ... | 1991 | 2010861 |
parasites, pets, and people. | it is important for the family physician to understand that patients' relationships with their pets play an important role in helping maintain mental and physical health yet provide the potential for causing illness in the patient. toxocara canis (dog roundworm) and toxocara cati (cat roundworm) are the ascarids most commonly responsible for vlm and ocular larva migrans in humans. these roundworms live in their adult stage in the small intestine of the dog and cat where their eggs are passed in ... | 1991 | 2011635 |
effects of milbemycin oxime on adult ancylostoma caninum and uncinaria stenocephala in dogs with experimentally induced infections. | | 1991 | 2021256 |
efficacy of nitroscanate against naturally acquired infection with ancylostoma caninum, dipylidium caninum, and trichuris vulpis in dogs. | eighteen dogs with naturally acquired helminth infections were used to evaluate the efficacy of nitroscanate against ancylostoma caninum, dipylidium caninum, and trichuris vulpis. approximately 15 minutes before treatment, the dogs were given 100 to 200 g of canned dog food. ten dogs were treated with nitroscanate (50 mg/kg of body weight, po), and 8 dogs were given placebo tablets po. the dogs were euthanatized and necropsied 10 days after treatment and helminths were recovered from the small i ... | 1991 | 2053726 |
serum-stimulated feeding in vitro by third-stage infective larvae of the canine hookworm ancylostoma caninum. | developmentally arrested nonfeeding infective larvae of hookworms resume development after entry into the host, presumably in response to a signal encountered during invasion. logically, an initial step in the resumption of development might be the resumption of feeding. an in vitro assay for feeding is described for the third-stage larvae of the canine hookworm ancylostoma caninum. populations of larvae incubated under hostlike conditions in the presence of 10% canine serum resume feeding withi ... | 1990 | 2112598 |
extrusion of the residual body in spermatids of ancylostoma caninum (nematoda, strongyloidea). | transmission electron microscopy reveals that the spermatocytes of the hookworm ancylostoma caninum contain an abundance of golgi complexes, ribosomes, specialized membranous organelles, and long strands of smooth endoplasmic reticulum. these organelles remain abundant until the early spermatid stage of sperm development, when they reach their maximum abundance and maturity and the production of new ones ceases. golgi complexes, ribosomes, and excess ser, which are not functional after this stag ... | 1990 | 2160020 |
metalloproteases of infective ancylostoma hookworm larvae and their possible functions in tissue invasion and ecdysis. | to infect their hosts, hookworm larvae must exsheath and migrate through connective tissue. a modified in vitro skin chamber was used to show that the human hookworm ancylostoma duodenale and the zoonotic canine hookworm ancylostoma caninum penetrate epidermis, basement membrane, and dermis in similar ways. these similarities in tissue invasion properties reflect the observed biochemical similarities in parasite protease composition. the larvae of both species contain protease activity that is i ... | 1990 | 2254016 |
field trials of the anthelmintic efficacy of nitroscanate and mebendazole in dogs. | the efficacies of nitroscanate and mebendazole against nematodes and dipylidium caninum were compared by the examination of the faeces of 155 dogs. in unweaned puppies nitroscanate acted significantly faster and was significantly more effective than mebendazole against toxocara canis. in adult dogs, both drugs had a low efficacy against trichuris vulpis but a similarly good efficacy against other nematodes, with a tendency for nitroscanate to be more effective in reducing the prevalence of ancyl ... | 1990 | 2309388 |
effects of milbemycin oxime on adult hookworms in dogs with naturally acquired infections. | previous work indicated that adult ancylostoma caninum can be removed from experimentally infected dogs, using a formulation of milbemycin oxime at dosage of 0.5 mg/kg of body weight. to determine the efficacy of this treatment in dogs naturally infected with adult hookworms, 24 mixed-breed dogs with patent hookworm infections were purchased from an out-of-state vendor, and 6 male and 6 female dogs were assigned to either a control group or a group that would be treated. dogs were treated 10 day ... | 1990 | 2316928 |
biochemical and immunologic characterization of a major surface antigen of dirofilaria immitis infective larvae. | a 35 kd major surface antigen of dirofilaria immitis third-stage larvae was characterized biochemically and immunologically. living larvae were iodinated by using iodo-gen, iodosulfanilic acid, lactoperoxidase-glucose oxidase, and bolton-hunter reagents. detergent extracts of larvae labeled by the first three methods showed one major 35 kd component and a number of smaller components of about 6 kd, as analyzed by one-dimensional sds-page. in contrast, extracts from larvae labeled with the bolton ... | 1986 | 2419445 |
specificity of scolex and oncosphere antigens for the serological diagnosis of taeniid cestode infections in dogs. | groups of dogs raised free of helminths were monospecifically infected with the common nematodes toxocara canis, ancylostoma caninum and trichuris vulpis. serums from these dogs, and a group of dogs of unknown history but infected with dirofilaria immitis and dipylidium caninum, had levels of antibody to their homologous nematode antigens readily detectable by elisa. no cross-reactions were apparent when these serums were tested by elisa using oncosphere antigens of taenia hydatigena, t. pisifor ... | 1986 | 2421704 |
changes in serum enzyme activities in mice infected with single doses of ancylostoma caninum larvae. | aspartate transaminase, alanine transaminase, alkaline phosphatase and amylase levels were significantly increased in experimental female swiss albino mice infected with single doses of 500, 1,000 and 2,000 larvae of ancylostoma caninum. increase of enzyme levels is due to the leakage of large amounts of enzymes into the blood. the necrosis of cells during intestinal and extra intestinal phases of ancylostomiasis in mice is directly responsible for the increase of enzymes. | 1987 | 2437181 |
serum enzymes and worm load in mice infected with repeated doses of ancylostoma caninum larvae. | the alterations of serum enzymes induced in the host system of swiss albino mice by infection with ancylostoma caninum larvae have been studied in multiple doses of infection. it was found that the level of transaminases, alkaline phosphatase and amylase increased significantly throughout the infection period when compared with controls. in infected animals, increase of enzymes was influenced by the host-parasite interactions caused due to the retained concentration of larval antigens. | 1988 | 2457613 |
efficacy of nemadectin, a new broad-spectrum endectocide, against natural infections of canine gastrointestinal helminths. | nemadectin, a new broad-spectrum endectocide, was highly efficacious against natural infections of all the major canine gastrointestinal helminths. at single oral dosages of 0.2-0.4 mg kg-1 body weight (bw), a liquid formulation administered in gelatin capsules was 100% effective in eliminating natural infections of toxocara canis, toxascaris leonina, ancylostoma caninum and uncinaria stenocephala. tablets (267 mg) containing 4.6% nemadectin given at a rate of 1/3 tablet per 20 kg bw (0.2 mg nem ... | 1989 | 2617829 |
enzymes activity and worm burden in intestine and liver of mice infected with single doses of ancylostoma caninum larvae. | transaminases increased significantly in the intestine and liver of mice infected with 500, 1,000 and 2,000 doses of ancylostoma caninum larvae. the level of increase remained higher than those of controls throughout the experimental period. the rise of enzymes was mainly due to the pathological changes caused by the migrating larvae within the organs. | 1989 | 2625550 |
a survey of helminths in domestic cats in the pretoria area of transvaal, republic of south africa. part 1: the prevalence and comparison of burdens of helminths in adult and juvenile cats. | the helminths found in 1,502 necropsied cats were examined. the findings indicated that 65% of the cats were infested. the most prevalent helminths encountered were ancylostoma tubaeforme (41%), ancylostoma braziliense (25%), dipylidium caninum (23%), toxocara cati (11%), taenia taeniaeformis (7.7%), ancylostoma caninum (3.3%), joyeuxiella fuhrmanni (2.5%), ancylostoma ceylanicum (1.4%), and physaloptera praeputialis (1.3%). the following helminths were recorded in fewer than 1% of the cats: cen ... | 1989 | 2634770 |
ancylostoma caninum in british greyhounds. | | 1989 | 2718327 |