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enzyme-linked immunosorbent assay for the diagnosis of clinical and subclinical melioidosis.an enzyme-linked immunosorbent assay (elisa) for the detection of specific igg and igm antibody to pseudomonas pseudomallei was developed. the igg-elisa was compared with the indirect fluorescence assay for igg antibody (igg-ifa) and the indirect hemagglutination (iha) test in studies with serum specimens from persons from endemic areas for melioidosis and from persons from nonendemic areas of australia. the sensitivity and specificity of the igg-elisa were 90% and 99%, respectively, comparable ...19892760482
multiple splenic abscesses following pseudomonas sepsis.splenic abscess is an unusual clinical entity, which in most cases is secondary to metastatic spread of bacteria from a primary site of infection. before the antibiotic era, salmonella typhi was a common offending organism but now staphylococci and streptococci are predominant organisms. we report two rare cases of multiple splenic abscesses caused by pseudomonas infection. one case followed pseudomonas septicaemia and the other was secondary to pseudomonas pseudomallei osteomyletis of the femur ...19892774478
substrate response in acid phosphatase activity of pseudomonas pseudomallei and pseudomonas cepacia, with special reference to tyrosine phosphatase.the substrate response in acid phosphatase activity of pseudomonas pseudomallei and pseudomonas cepacia was examined with different phosphate esters including hexose phosphates and phosphoaminoacids in a whole cell assay system. the enzymatic activity against each substrate was evaluated in terms of percent activity to that against para-nitrophenyl phosphate set as 100. a remarkable finding was that the phosphatase reaction was the highest with phosphotyrosine or phosphoserine as substrate showi ...19911725886
in-vitro susceptibility of pseudomonas pseudomallei to dna gyrase inhibitors. 19872824429
[characteristics of the conjugation transfer of the plasmids of p-1-group incompatibility to pseudomonas pseudomallei strains]. 19882854878
antibiotic resistance in pseudomonas pseudomallei. 19882896855
pseudomonas pseudomallei and sudden unexplained death in thai construction workers. 19901978101
in vitro susceptibility of strains of pseudomonas pseudomallei isolated in thailand and hong kong to some newer beta-lactam antibiotics and quinolone derivatives. 19862934486
[prospects of the use of chromosomal transformation for the identification of the causative agent melioidosis].prospects for the use of chromosomal transformation for the identification of pseudomonas pseudomallei and some other medically important pseudomonas species are considered. the method is simple, reproducible and highly specific. it permits the screening of a great number of cultures and can facilitate further study of the biology of p. pseudomallei and the epidemiology of melioidosis.19883057775
[infection with pseudomonas pseudomallei].melioidosis, a severe, often fatal disease caused by infection with pseudomonas pseudomallei, has been thought to be a rare endemic disease relatively limited to the areas 20 degrees on either side of the equator. however, an increasing number of people travelling to these areas are reportedly suffering from this disease. it is timely to review this disease for doctors who are unfamiliar with this disease. p. pseudomallei, first discovered by whitmore and krishnaswami in 1912, is a gram-negative ...19902273564
[automated micromethod for the determination of the utilization of carbon sources by clinically significant pseudomonas species].the assimilation of 43 different carbon substrates by 93 clinical strains of pseudomonas aeruginosa was studied by a new miniaturized rapid method. reading of assimilation results was done photometrically after 18-20 h incubation and the resulting data were captured and stored by a microcomputer. the differentiating capacity of the assimilation tests were verified by comparing the results of 41 strains of pseudomonas fluorescens, 48 strains of pseudomonas putida, 52 strains of pseudomonas maltop ...19873118596
melioidosis: the tip of the iceberg?for nearly 80 years clinical melioidosis has been considered a rare disease. this bacterial infection is caused by pseudomonas pseudomallei, a saprophyte found in soil and surface water of endemic areas. consequently, those who have most contact with soil, the rural poor, are likely to be at greatest risk of infection. since the diversity of clinical manifestations necessitates the isolation and identification of the causative organism for a definitive diagnosis of melioidosis and the population ...19912004347
neonatal melioidosis: a report of 5 cases.melioidosis, caused by pseudomonas pseudomallei, occurs in tropical areas and is diagnosed mostly in adults. in khon kaen, a province of northeast thailand, five cases of infantile melioidosis were managed at srinagarind hospital. the patient's specimens were submitted to microbiologic and serologic examination for p. pseudomallei demonstrated by indirect hemagglutination. possible modes of transmission such as environment, perinatal exposure and venereal transmission were investigated.19883174307
melioidosis. forgotten, but not gone!melioidosis, infection by the soil bacterium pseudomonas pseudomallei, has the potential for prolonged latency with recrudescence into an acute, often fulminating, and fatal infection. although the organism is never found in north america, infection is endemic in areas of southeast asia, and populations of service personnel exposed during the vietnam war and southeast asian immigrants are at risk of severe recrudescent disease. diagnosis, however, has been missed or delayed because of lack of fa ...19912001144
isolated articular melioidosis.melioidosis is an infection caused by a gram-negative bacilli, pseudomonas pseudomallei. this organism can cause fatal infection in domestic animals and are probably transmitted to humans by soil contamination of skin abrasions, ingestion, and inhalation. melioidosis is being increasingly diagnosed in western countries in other than its endemic areas of tropical and subtropical zones. in the past, only a few single case reports of articular melioidosis were published in english journals, and alm ...19912044275
resistance of pseudomonas pseudomallei to normal human serum bactericidal action.the effect of human normal serum (hns) on pseudomonas pseudomallei was determined. it is apparent from our data that the organism is resistant to the normal serum bactericidal mechanism. ancillary experiments to confirm this serum-resistant property of p. pseudomallei were done by examining the effects of growth phase conditions of the bacteria (i.e., logarithmic and stationary phases) and different buffered systems used as diluent in our bactericidal assay. results obtained showed similar degre ...19883193910
in vitro activities of the newer beta-lactam and quinolone antimicrobial agents against pseudomonas pseudomallei.imipenem was highly active and bactericidal against all 100 strains of pseudomonas pseudomallei tested, followed in activity by piperacillin, carumonam, ceftazidime, cefotaxime, and ceftriaxone. the addition of clavulanic acid significantly increased the activities of both amoxicillin and ticarcillin. ciprofloxacin and norfloxacin showed poor activity against test strains.19883196005
in vitro susceptibilities of pseudomonas pseudomallei to 27 antimicrobial agents.clinical isolates of pseudomonas pseudomallei isolated in thailand from 1981 to 1989 were tested for their in vitro susceptibilities to 27 antimicrobial agents, including older and newer quinolones, broad-spectrum cephems, carbapenems, monobactams, penicillins, tetracyclines, chloramphenicol, rifamycin, sulfamethoxazole, trimethoprim, and fosfomycin. tosufloxacin, meropenem, cs-533, and minocycline were active against p. pseudomallei at levels comparable to or even greater than those of antimicr ...19902291671
characterization of monoclonal antibodies to protein antigen of salmonella typhi.two monoclonal antibodies were produced against protein antigens of salmonella typhi. one of the antibodies (stp14) belongs to the immunoglobulin g1k subclass, and the other (stp13) was assigned to the immunoglobulin g2a(kappa) subclass. both antibodies could recognize the 34.0-kilodalton protein antigen from s. typhi. the specificity of these antibodies was tested by immunoblotting with a panel of crude protein antigens from 12 bacteria causing enteric fever and enteric fever-like illness: s. t ...19883281976
evaluation of a modified complement fixation test and an indirect hemagglutination test for the serodiagnosis of melioidosis in pigs.a complement fixation test modified by the addition of porcine serum and an indirect hemagglutination test were used to detect antibodies to pseudomonas pseudomallei in pigs. these tests together with cultural examinations were carried out with 250 pigs. the sensitivity and specificity values were 79.3 and 99.5% and 82.8 and 93.2% for the modified complement fixation and hemagglutination tests, respectively. when results from the combination of both tests were considered, the values were 86.2 an ...19902203818
blood culture techniques for the diagnosis of melioidosis.the effects of variations in laboratory technique on the speed and sensitivity of isolation of pseudomonas pseudomallei from blood were evaluated prospectively. pseudomonas pseudomallei was isolated from 154 of 546 cultures from 325 patients with suspected or confirmed melioidosis. subcultures after 12 to 24 and 36 to 48 hours of incubation were positive in 52.3% and 80.8% respectively. the yields from 20 ml (blood to broth ratio 1:4) and 50 ml (blood to broth ratio 1:10) brain heart infusion br ...19902226493
production of hemolysin and other extracellular enzymes by clinical isolates of pseudomonas pseudomallei.one hundred clinical isolates of pseudomonas pseudomallei from humans were tested for their ability to produce extracellular, biologically active substances which are thought to contribute to the virulence of pseudomonas species. all isolates produced at least on extracellular enzyme; 91 strains were positive for lecithinase, lipase, and protease; but none was positive for elastase. ninety-three strains produced a hemolysin which was detectable around the heavy growth on saline-washed sheep eryt ...19902229359
[ecological and biological maintenance of sapronoses exemplified by melioidosis].the growth and death of pseudomonas pseudomallei, the causative agent of melioidosis, in the soil and the antigenic properties of this microorganism in the soil, in culture media, and in the body of animals have been studied. as revealed in this study, p. pseudomallei can grow in nonsterile soil substrates without the loss of virulence and changes in its antigenic structure. in the body of animals this microorganism rapidly adapts its virulence to host species by the transformation of its antige ...19883389005
activities of five new fluoroquinolones against pseudomonas pseudomallei.thirty-four isolates of pseudomonas pseudomallei were tested by a broth microdilution technique for susceptibility to amifloxacin, ciprofloxacin, enoxacin, norfloxacin, and ofloxacin. ciprofloxacin was the most active agent tested, with an mic for 90% of the strains tested of 8 micrograms/ml. these in vitro results suggest that the fluoroquinolones tested would not be optimal for therapy of melioidosis.19883415212
pseudomonas pseudomallei: danger in the paddy fields. 19912068733
brain abscess due to pseudomonas pseudomallei.a brain abscess due to pseudomonas pseudomallei is presented. central nervous system involvement in melioidosis is rare and generally occurs in association with disseminated infection. the importance of early diagnosis and prompt treatment with prolonged antibiotic therapy is emphasised.19863458450
survival of pseudomonas pseudomallei in human phagocytes.pseudomonas pseudomallei causes the disease melioidosis, with protean manifestations, protracted clinical course and unpredictable response to antimicrobial treatment. intracellular location of the organism is suspected to be the cause of these properties. this study was undertaken to examine the intracellular growth of this bacterium. intracellular growth and survival was assessed at different time intervals, by gram's stain and electronmicroscopic examination. during the first 5 h, the numbers ...19902304065
isolation of indigenous larvicidal microbial control agents of mosquitos: the malaysian experience.a nationwide screening program searching for microbial control agents of mosquitos was initiated in malaysia in 1986. a total of 725 samples were collected and 2,394 bacterial colonies were isolated and screened for larvicidal activity. from such screening, 20 bacillus thuringiensis, 6 b. sphaericus, 1 clostridium bifermentans and 2 pseudomonas pseudomallei larvicidal isolates were obtained. of these, a new b. thuringiensis named as subspecies malaysianensis was found, while the c. bifermentans ...19902237596
beta-lactamase of pseudomonas pseudomallei and its contribution to antibiotic resistance.beta-lactamase production was examined in nine strains of pseudomonas pseudomallei isolated from human, animal and environmental sources in thailand and hong kong. all produced the same weakly inducible, membrane associated chromosomal cephalosporinase, which had a molecular weight of 29,500 and an isoelectric point of 7.4-7.7. the enzyme resembled the cefuroximases of ps. cepacia and proteus vulgaris, but differed from the class i cephalosporinases typical of ps. aeruginosa and most enterobacte ...19873500161
melioidosis: a serological survey in a tuberculosis sanatorium in hong kong.a serological survey of 275 chinese patients with underlying pulmonary diseases in a tuberculosis sanatorium in hong kong showed that 39 (14%) had haemagglutinating antibody (ha) against pseudomonas pseudomallei in a titre of 1: 80 or above. only 9 of these 39 patients had travelled to endemic areas, suggesting that at least 30 patients (11%) had been exposed to ps. pseudomallei locally. females are affected as often as males, and the seropositive rate is the same whether patients are immunosupp ...19873503401
a competitive immunosorbent assay for detection of pseudomonas pseudomallei exotoxin.the development of monoclonal antibody and enzyme-linked immunosorbent assay (elisa) techniques has made possible the detection of specific antigens at extremely low concentrations. diagnosis of recalcitrant diseases such as melioidosis depends upon either early isolation and identification of the causative organism or the identification of a specific marker antigen, pseudomonas pseudomallei exotoxin, in serum; the latter is better because it allows more rapid and simple diagnosis. a method of d ...19873585969
subacute pulmonary melioidosis in a temperate climate.previous reports of cases of melioidosis that were seen in nonendemic areas of australia describe recrudescences of latent infection. we describe the case of a patient who presented in the cooler climate of melbourne with a probable primary, subacute pulmonary infection with pseudomonas pseudomallei. this case illustrates several points that bear consideration in the management of atypical pneumonia and, more specifically, pulmonary melioidosis. historical and occupational clues are easily misse ...19873600459
experimental infection of normal and immunosuppressed pigs with pseudomonas pseudomallei.a single dose of 5 x 10(8) bacilli of pseudomonas pseudomallei by intratracheal injection resulted in acute (21 cases) or chronic (19 cases) melioidosis in 40 of 48 pigs. fifteen (10 acute and 5 chronic) had been immunosuppressed by cyclophosphamide before inoculation. the major clinical signs were initial fever, marked neutrophilia and, in the acute cases, respiratory distress. there were no signs of the nasal and ocular discharge, paresis or diarrhoea seen in acute cases in south-east asia. th ...19902344335
melioidosis: epidemiology and antibiogram of cases in singapore.there has been an increased incidence of melioidosis in singapore. the disease affects mainly males, older patients and a disproportionately higher number of indians and malays. possible predisposing illness include diabetes mellitus. most patients are bacteraemic. mortality rate is 72% for bacteraemic patients, as compared to 32% for non-bacteraemic patients. local strains of pseudomonas pseudomallei have been consistently sensitive to ceftazidime, chloramphenicol and piperacillin, and nearly a ...19902255929
[the ultrastructural characteristics of the causative agent of melioidosis and its interaction with phagocytes in vivo].the electron microscopic studies have established that the virulent strain of pseudomonas pseudomallei c-141, an agent of melioidosis, being intraperitoneally administered to guinea pigs, forms in vivo three morphological variants. one variant is capsule-free, while two others have a capsule which in the second variant may be referred by its characters to the microcapsule and in the third one to the macrocapsule. it has been shown that under the interaction of these three morphological variants ...19902377083
amoxycillin-clavulanic acid treatment of melioidosis.melioidosis is a serious infection with high acute mortality, and a high rate of relapse despite protracted antimicrobial treatment. the current recommended conventional oral treatment regimen is a 4-drug combination of high-dose chloramphenicol, doxycycline and trimethoprim-sulphamethoxazole given for between 6 weeks and 6 months. we have evaluated prospectively the use of amoxycillin-clavulanic acid, to which pseudomonas pseudomallei is consistently sensitive in vitro, for the oral maintenance ...19911781006
[spontaneous genetic transformation in pseudomonas pseudomallei].spontaneous genetic transformation has been registered in pseudomonas pseudomallei cells. transforming frequencies registered reach 10(-4)-10(-5). spontaneous transformation has been simulated for pseudomonas pseudomallei in soil. intrageneric spontaneous transformation has been demonstrated to occur between pseudomonas pseudomallei and pseudomonas mallei.19853842757
pseudomonas pseudomallei pneumonia with septicemia--case report.a case of pseudomonas pseudomallei pneumonia with septicemia is described. the onset was insidious with paucity of systemic symptoms except fever. diabetes mellitus and alcoholism were associated problems. initially blood cultures were negative but subsequently p. pseudomallei was isolated. the outcome was fatal. unless diagnosed early and treated appropriately, patients often succumb to septicemic shock.19892609180
pseudomonas pseudomallei infection from drowning: the first reported case in taiwan.we report a case of pseudomonas pseudomallei infection, in which the patient acquired the bacteria by aspiration of river water after a drowning incident near manila, the philippines. the pulmonary form of melioidosis was noted at the onset, but septicemia developed at a later stage. positive blood cultures were obtained 17 days after the accident. the patient was treated successfully with a combination of amikacin and cephalothin. this is the first report of p. pseudomallei infection documented ...19854044794
high activity of acid phosphatase of pseudomonas pseudomallei as a possible attribute relating to its pathogenicity.phosphatase activities were compared quantitatively among selected species of pseudomonads. p. pseudomallei showed the highest activity of a bell-shaped ph pattern with a peak at around ph 5.0. p. cepacia had a similar pattern of milder intensity. in contrast, p. aeruginosa revealed an alkaline phosphatase activity with a ph optimum higher than 8.0, but the level of activity was much lower than those of the above two species. the enzymatic reactions of other species were slight or negligible at ...19892632842
melioidosis with multiple cerebral abscesses.melioidosis from pseudomonas pseudomallei is common in endemic areas (particularly southeast asia) and is being recognized with increasing frequency in developed countries. central nervous system involvement is a rare complication with a high mortality. a patient with multiple cerebral abscesses caused by this organism is presented to demonstrate that successful treatment is possible when a high index of clinical suspicion leads to early diagnosis.19892653340
melioidosis in malaysia. iv. intensive ecological study of carey island, selangor, for pseudomonas pseudomallei. 19694244150
morphological and cytological effects of carbenicillin on pseudomonas pseudomallei. 19744371050
inhibition of pseudomonas pseudomallei by carbenicillin, in vitro. 19744418167
pseudomonas pseudomallei: 1. infection in thailand. 19744499415
identification of pseudomonas pseudomallei. 19724552650
melioidoses, pseudomonas pseudomallei and the clinical laboratory. 19724556761
melioidosis: review and update.melioidosis prevails in southeast asia and northern australia. sporadic cases have been increasingly reported from countries located between 20 degrees north latitude and 20 degrees south latitude as well as in travelers and in soldiers who have resided in these areas. the organisms are commonly found in water and soil and are usually transmitted to humans by cutaneous or respiratory routes. clinical manifestations range from subclinical infection to overwhelming septicemia that resembles dissem ...19892665001
a serologic survey of military personnel and dogs in thailand and south vietnam for antibodies to arboviruses, rickettsia tsutsugamushi, and pseudomonas pseudomallei. 19724627553
[melioidosis and its causative agent: pseudomonas pseudomallei]. 19734703906
the antimicrobial susceptibility of pseudomonas pseudomallei. emergence of resistance in vitro and during treatment.we have measured the in-vitro activity of 27 antimicrobials against 211 clinical and ten reference strains of pseudomonas pseudomallei. imipenem was the most active antibiotic tested, followed by piperacillin, doxycycline, amoxycillin/clavulanic acid, cefixime, cefetamet, azlocillin and ceftazidime, all of which had mics of less than or equal to 2 mg/l for the majority of strains. the measured mics were dependent on the media and inocula used, to an extent which varied with the antibiotic class ...19892681116
antibiotic susceptibility of pseudomonas pseudomallei.the in vitro activity of various antibiotics against pseudomonas pseudomallei was studied. the tetracyclines were the most active, followed by gentamicin, kanamycin, novobiocin, chloramphenicol, rifampin, cycloserine, erythromycin, and ampicillin.19734790939
pseudomonas pseudomallei (malleomyces pseudomallei) orchitis in a boar. 19744839140
selection and rapid identification of pseudomonas pseudomallei from other gram-negative bacteria. 19684871604
diagnostic criteria for differentiation of pseudomonads pathogenic for man.to determine the most useful diagnostic characters for the differentiation of pseudomonads pathogenic for man, including pseudomonas maltophilia (alcaligenes bookeri), p. stutzeri (bacillus denitrificans), p. pseudomallei (malleomyces pseudomallei), and apyocyanogenic strains of p. aeruginosa, a comparative examination was made of 58 strains of these bacilli for their morphological and biochemical characteristics. it was concluded that the criteria for differentiating these bacteria are type of ...19684879213
interactions in vitro between agents used to treat melioidosis.combinations of antimicrobial agents are usually recommended for the treatment of melioidosis. in thailand, the conventional treatment regimen for pseudomonas pseudomallei infections is a combination of chloramphenicol, doxycycline and cotrimoxazole. we have consistently observed antagonism between these agents during routine disc susceptibility testing. interactions between these antimicrobials were studied further by a chequerboard microdilution method, using five clinical isolates of p. pseud ...19892681117
identification of pseudomonas pseudomallei. 19714933030
[comparative action of malleomyces mallei, pseudomonas pseudomallei and pseudomonas aeruginosa on various nitrogen substances]. 19654953183
[thermostable antigens of pseudomonas pseudomallei and of malleomyces mallei and their characteristics in common]. 19674961924
[precipitating and agglutinating antigens of pseudomonas pseudomallei (whitmore's b.). i. thermostable and thermolabile complexes. serological typing]. 19704989883
[precipitating and agglutinating antigens of pseudomonas pseudomallei (whitmore's bacillus). ii. demonstration of precitating antigens common to yersinia pestis and pseudomonas pseudomallei]. 19704995342
growth of pseudomonas pseudomallei & ps. aeruginosa on petroleum fractions. 19714999149
melioidosis: a major cause of community-acquired septicemia in northeastern thailand.in a prospective study of all patients with pseudomonas pseudomallei infections admitted to a large provincial hospital in northeastern thailand, 63 cases of septicemic melioidosis and 206 patients with other community-acquired septicemias were documented during a 1-y period. apart from p. pseudomallei, the spectrum of bacteria isolated from blood cultures and the overall mortality (32%) were similar to those previously reported elsewhere. death from septicemia was associated with failure to dev ...19892708842
focal encephalitis due to pseudomonas pseudomallei. 19715107344
splenic abscess at siriraj hospital, thailand.splenic abscess is an unusual disease and may be presented either as a localized area of infection in the spleen or as a part of generalized sepsis. population-based autopsy studies have established the incidence of splenic abscess at between 0.2-0.7 per cent. an eleven-year retrospective study of cases of splenic abscess treated at siriraj hospital, a total of 9 cases, is presented. pseudomonas pseudomallei is the most frequent causative agent, found in one-third of the cases, especially if the ...19892809452
acute suppurative parotitis caused by pseudomonas pseudomallei in children.during a prospective clinical study of melioidosis in northeast thailand, suppurative parotitis was observed as a characteristic presentation in children. parotitis constituted 6.3% of all culture-positive melioidosis and 38% of melioidosis in children. nine cases are described. none had apparent predisposition to infection, although two patients developed rising mumps virus antibody titers, suggesting a possible relation between these conditions. complications included abscess formation (nine), ...19892926159
effect of gentamicin on pseudomonas pseudomallei. 19715126250
the sensitivity of pseudomonas pseudomallei to trimethoprim and sulphamethoxazole in vitro.twelve out of 14 strains of pseudomonas pseudomallei were inhibited in vitro by a combination of trimethoprim 1 mug per ml and sulphamethoxazole 20 mug per ml or by lower concentrations. of the remaining strains, one was marginally more resistant and one was distinctly so. in tests utilizing two of the sensitive strains, inhibitory concentrations of the individual drugs exerted a bactericidal effect when combined.19715139985
pseudomonas pseudomallei: susceptibility to chemotherapeutic agents. 19705197996
pseudomonas pseudomallei and melioidosis, with special reference to the status in thailand.melioidosis is a long-known disease since 1912, but only quite recently we have obtained the knowledges about its actual clinical and epidemiological features. the disease is so unique in having a wide spectrum of disease course and clinical manifestation. the causative agent, p. pseudomallei, is free-living bacterium in the natural environments (soil and surface water) of tropical and subtropical areas. just like legionnaires' disease, melioidosis is a good example of infectious disease in whic ...19883075004
[multiplication and virulence of septicemic and blood-infective agents in the organism of the infected animals and in their cadavers. xvi. study on models of pseudomonas pseudomallei experimental infections]. 19695398234
[biological and biochemical studies of the growth of virulence of several septicemic and blood-infective agents. vi. dehydrogenase activity of pseudomonas pseudomallei with various virulence]. 19695398239
nucleic acid similarities among pseudomonas pseudomallei, pseudomonas multivorans, and actinobacillus mallei.annealing experiments on membrane filters were carried out with deoxyribonucleic acids (dna) from selected strains of the nomen-species of pseudomonas, actinobacillus, chromobacterium, and micrococcus, with the use of dna of pseudomonas pseudomallei and actinobacillus mallei as reference materials. under the usual conditions employed in these experiments, the results were not quantitatively reproducible. incorporation of dimethylsulfoxide (dmso) into the incubation medium greatly increased diffe ...19705438051
pseudomonas pseudomallei in a case of chronic melioidosis. 19705471230
laboratory evaluation of rifampin and other antimicrobial agents against selected strains of pseudomonas pseudomallei. 19705521374
[transaminases and virulence. i. pseudomonas pseudomallei variants with different virulence]. 19705526115
[polysaccharide-containing complexes of malleomyces pseudomallei]. 19685733582
the control of experimental infection in mice produced by pseudomonas pseudomallei. 19695787609
melioidosis in malaysia. i. a method for isolation of pseudomonas pseudomallei from soil and surface water. 19695810796
melioidosis in malaysia. ii. distribution of pseudomonas pseudomallei in soil and surface water. 19695810797
melioidosis in malaysia. 3. antibodies to pseudomonas pseudomallei in the human population. 19695817889
osteomyelitis due to pseudomonas pseudomallei. 19665952299
a comparative study of pseudomonas pseudomallei and bacillus mallei. 19665962362
isolation of pseudomonas pseudomallei from an aborted goat foetus. 19666007974
septic arthritis due to pseudomonas pseudomallei. 19676057646
[identification of pseudomonas pseudomallei]. 19836194365
susceptibility of pseudomonas pseudomallei to new beta-lactam and aminoglycoside antibiotics.pseudomonas pseudomallei is resistant to many antimicrobial agents. we determined the susceptibility to twelve beta-lactams and six aminoglycosides of twelve isolates of p. pseudomallei. imipenem (mic range 0.5-1.0 mg/l; mic90 1.0 mg/l), ceftazidime (mic range 1-8 mg/l; mic90 8.0 mg/l), amoxycillin/clavulanate (mic range 4-8 mg/l; mic90 8.0 mg/l), piperacillin (mic range 4-16 mg/l; mic90 8.0 mg/l), and carumonam (mic range 4-16 mg/l; mic90 8.0 mg/l) were the most active. aminoglycosides were rel ...19883162898
[biological effect of d,l-ureidosuccinic acid dihydrazide on pseudomonas pseudomallei and salmonella typhimurium]. 19826293275
biological effect of d,l-ureidosuccinic acid dihydrazide on pseudomonas pseudomallei and salmonella typhimurium. 19826293407
melioidosis with brain abscess.central nervous system involvement in melioidosis is rare. we describe a 48 year old woman who developed septicaemia and a brain abscess due to pseudomonas pseudomallei. since there is a continuing practical problem in bacteriological confirmation of the aetiological agent, diagnosis of melioidosis has to be made on clinical suspicion.19883174527
[drug sensitivity of pseudomonas pseudomallei]. 19836351503
evaluation of four serological tests for the diagnosis of caprine melioidosis.a complement fixation (cf) test, 2 indirect haemagglutination (iha-a; iha-l) tests which differed in antigen preparation and technique, and a microtitre agglutination (ma) test were compared in the serodiagnosis of melioidosis in goats. one hundred and eighteen experimental serums and 3143 field serums from goats in endemic and non-endemic areas of north queensland were used in the evaluation. culture of samples for pseudomonas pseudomallei from 112 goats provided substantiating evidence of infe ...19883190597
biological effect of l-asparagine acid hydrazide on pseudomonas pseudomallei and salmonella typhimurium. 19836370195
[diagnosis of the whitmore bacillus in the laboratory].after realization of a new synthetic medium for whitmore bacillus enrichment and isolation, the authors describe a new specific and immunologic process for pseudomonas pseudomallei isolation from very polluted samples.19836370480
[relative biological effect of l-aspartic acid hydrazide on pseudomonas pseudomallei and salmonella typhimurium]. 19846377831
childhood melioidosis in northeastern thailand.eighteen cases of childhood melioidosis in northeastern thailand were reviewed. the mean age was 6.8 years with a range from eight months to 15 years. twelve cases (66.7%) had localized melioidosis, six of which had pneumonia. three patients were diagnosed as pharyngocervical melioidosis, the newly recognized syndrome. nine cases (50.0%) had associated diseases including dengue hemorrhagic fever (dhf) in five cases. in all five cases, melioidosis was diagnosed during the convalescent stage as a ...19883227408
clinical and pathological observations on goats experimentally infected with pseudomonas pseudomallei.the effects in goats of the subcutaneous injection of varying doses of pseudomonas pseudomallei (90 to 500,000 bacilli) suspended in normal saline are described. high doses (greater than or equal to 500 bacilli) caused acute, fatal infections. lower doses (90 to 225 bacilli) caused acute or chronic disease when infection became established. however, 11 of 18 goats injected with the lower doses of bacilli showed no sign of infection on clinical or bacteriological examination. response to antibiot ...19883355451
first report of septicaemic melioidosis in hong kong.septicaemia due to pseudomonas pseudomallei was found in five patients; it complicated pneumonia in three. four patients were old and had diabetes mellitus; the fifth patient, though young, was immunocompromised by steroid therapy. the clinical features were indistinguishable from those of other gram-negative septicaemia. four of the patients died. this was the first report of septicaemic melioidosis in hong kong where the disease might be endemic. soil sampling and serological survey gave furth ...19846485053
in vitro activity of various cephalosporins against pseudomonas pseudomallei. 19846491381
melioidosis: a reminder.recrudescent pulmonary melioidosis developed in two patients 12 and 16 years after their last travels to an endemic area. in one, a clinically silent prostatic abscess may have been the focus; and in both, the diagnosis was difficult to make even when the laboratory was notified of the possibility of infection with pseudomonas pseudomallei. recrudescent melioidosis should be considered in febrile patients who have been in endemic areas regardless of the interval from last exposure to the develop ...19883364451
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