| mycobacterium celatum as a cause of disseminated infection in an aids patient. | | 1997 | 11864190 |
| pneumonia and bacteremia due to mycobacterium celatum masquerading as mycobacterium xenopi in patients with aids: an underdiagnosed problem? | a newly described species of mycobacteria, mycobacterium celatum, has rarely been reported as a cause of localized and disseminated human disease and can easily be misidentified as mycobacterium xenopi when identification is based on biochemical testing alone. we report two cases of pneumonia and bacteremia due to m. celatum in patients with aids. in one case, diagnosis and initiation of therapy were delayed by misidentification of the infecting organism as m. xenopi. genomic analysis or high-pe ... | 1997 | 9114137 |
| mycobacterium celatum pulmonary infection in the immunocompetent: case report and review. | mycobacterium celatum has been shown to cause disease in immunocompromised patients. we report a case of serious pulmonary infection caused by m. celatum in an apparently immunocompetent patient and review the characteristics of two other reported cases. clinical and radiologic symptoms and signs included cough, malaise, and weight loss associated with cavitary lesions and pulmonary infiltrates. although m. celatum is easy to detect in clinical specimens by liquid and solid media, it may be misi ... | 2003 | 12643843 |
| [disseminated infection with mycobacterium celatum]. | a 29-year-old patient with aids was hospitalized with weight loss, fever and cough. mycobacterial cultures from sputum, blood and bronchoalveolar lavage became positive after 3 weeks' incubation. when using a dna probe for identification of mycobacterium tuberculosis complex, a weakly positive signal was obtained. tuberculosis was suspected and treatment was started with isoniazid, ethambutol and ciprofloxacin. sequencing of the gene of the 16s rrna, however, identified the isolates as belonging ... | 1996 | 8701244 |
| mycobacterium branderi sp. nov., a new potential human pathogen. | a number of mycobacterial strains with similar growth characteristics, metabolic properties, and lipid compositions, which were previously placed in the helsinki group (e. brander, e. jantzen, r. huttunen, a. juntunen, and m.-l. katila, j. clin. microbiol. 30:1972-1975, 1992), were characterized by performing 16s rrna gene sequencing. of the 14 strains studied, 9 had a unique, previously undescribed sequence in the variable region of 16s rrna. these nine strains, all of which were isolated from ... | 1995 | 8590682 |
| mycobacterium celatum sp. nov. | a new slowly growing nonphotochromogenic mycobacterium species of clinical importance is described. the biochemical characteristics of this organism were similar to those of mycobacterium xenopi and members of the mycobacterium avium complex. however, none of the strains reacted with commercially available genetic probes for the m. avium complex. the strains were resistant to most antituberculosis drugs. multilocus enzyme electrophoresis revealed two original electrophoretic types, which was sug ... | 1993 | 8102246 |
| cervical lymphadenitis caused by mycobacterium celatum. | | 1994 | 7934400 |
| isolation of the newly described species mycobacterium celatum from aids patients. | mycobacterium celatum is a recently described species which, on the basis of conventional tests, may be misidentified as mycobacterium xenopi or as belonging to the mycobacterium avium complex. only genomic sequencing or high-performance liquid chromatography of cell wall mycolic acids can presently allow a correct identification of this mycobacterium. two cases of infection due to m. celatum, in aids patients, are described here. the quantitative susceptibility pattern of the isolates to a wide ... | 1995 | 7699029 |
| disseminated infection due to mycobacterium celatum in patient with aids. | | 1994 | 7914273 |
| a new group (type 3) of mycobacterium celatum isolated from aids patients in the london area. | we describe a new group (type 3) of the recently proposed species mycobacterium celatum isolated from eight patients with aids in london, england. sequences of genes coding for 16s rrna (embl accession no. z46664) showed a divergence of 17 bases from m. celatum type 2 reference isolates and a divergence of 7 bases from m. celatum type 1 reference isolates. a reference strain is available (nctc 12882). | 1995 | 7547311 |
| cross-reactivity of genetic probe for detection of mycobacterium tuberculosis with newly described species mycobacterium celatum. | an acridinium ester-labeled dna probe (accuprobe; gen-probe inc., san diego, calif.) for the identification of the mycobacterium tuberculosis complex gave discrepant results with the newly described species m. celatum. examination of 20 strains of m. celatum showed that 8 were positive with the probe; the remaining 12 were negative. | 1994 | 7512098 |
| molecular phylogeny of the mycobacterium avium complex demonstrates clinically meaningful divisions. | phylogenetic analysis of nucleotide sequence data is widely used for viral epidemiology. to explore its use in bacterial strain differentiation, the variable 16s-23s rdna internal transcribed spacer (its) in 24 clinical isolates originally identified as mycobacterium avium complex (mac) was sequenced. three isolates had an identical sequence that differed greatly from the rest. they belonged to the recently described mycobacterium celatum. the 21 mac clinical isolates gave 6 its sequences, each ... | 1994 | 8106762 |
| penile mass caused by the newly described organism mycobacterium celatum. | we report a penile infection in a man with the acquired immunodeficiency syndrome caused by a newly described infectious organism, mycobacterium celatum. mycobacterium tuberculosis is the only mycobacterial species previously reported to cause infection in the penis. this is only the third documented human infection with m celatum, and the first to involve the genitourinary system. | 1996 | 8607251 |
| misidentification and diagnostic delay caused by a false-positive amplified mycobacterium tuberculosis direct test in an immunocompetent patient with a mycobacterium celatum infection. | the gen-probe amplified mycobacterium tuberculosis direct test can give discrepant results directly in respiratory or cultured samples from patients infected with mycobacterium celatum, leading to inappropriate therapy for, in our case, an immunocompetent patient. | 2001 | 11376079 |
| genomic sequence and transcriptional analysis of a 23-kilobase mycobacterial linear plasmid: evidence for horizontal transfer and identification of plasmid maintenance systems. | linear plasmids were unknown in mycobacteria until recently. here, we report the complete nucleotide sequence of 23-kb linear plasmid pclp from mycobacterium celatum, an opportunistic pathogen. the sequence of pclp revealed at least 19 putative open reading frames (orfs). expression of pclp genes in exponential-phase cultures was determined by reverse transcriptase pcr (rt-pcr). twelve orfs were expressed, whereas no transcription of the 7 other orfs of pclp was detected. five of the 12 transcri ... | 2001 | 11244052 |
| mycobacterium celatum as a cause of disseminated infection in an aids patient. | | 1998 | 11864320 |
| disseminated mycobacterium celatum (type 3) infection in a domestic ferret (mustela putorius furo). | a 4-year-old male ferret (mustela putoriusfuro) had a 6-month history of weight loss and gradual development of depression and coughing. necropsy findings included pale gray tissue around the distal trachea, multiple nodules in the lungs, a single nodule in the stomach wall, gray foci in the liver, and enlarged lymph nodes. histologic examination revealed multifocal to coalescing granulomatous inflammation in the trachea, lungs, stomach, liver, and lymph nodes, with acid-fast bacteria in epithel ... | 2001 | 11467483 |
| analysis of the internal replication region of a mycobacterial linear plasmid. | linear plasmids have previously been identified by the authors in mycobacteria, the telomeres of which have terminal inverted repeats and covalently attached proteins. in this study, the replication of these unusual molecules was investigated by studying a 25 kb linear plasmid from the slow-growing species mycobacterium celatum called pclp. an internal region of pclp responsible for replication in mycobacterium smegmatis was identified. the nucleotide sequence of the minimum replication region o ... | 2000 | 10708369 |
| a new single-copy mycobacterial plasmid, pmf1, from mycobacterium fortuitum which is compatible with the pal5000 replicon. | a 9.2 kb cryptic mycobacterium fortuitum plasmid, pmf1, was isolated from strain 110 and its restriction map constructed. a 4.2 kb hindiii fragment of pmf1 was found to support replication in mycobacteria and this fragment was cloned and sequenced to characterize the replication elements of the plasmid. computer analysis identified a putative rep protein (362 amino acids) with high homology to the putative rep protein of the mycobacterium celatum plasmid pclp and limited homology, mostly in the ... | 2000 | 10708368 |
| mycobacterium celatum infection in two hiv-infected patients treated prophylactically with rifabutin. | mycobacterium celatum is a recently described slow-growing species. it was identified on the basis of genomic sequencing that differentiates three types. the present report describes two cases of mycobacterium celatum type 1 infection in patients with aids. both patients had cd4+ lymphocyte counts of < 10/mm3, were receiving rifabutin prophylaxis, and had attended the same treatment units. the minimum inhibitory concentration of rifabutin for both strains was 8 mg/l, which may account for the fa ... | 1998 | 9707313 |
| 16s rrna sequence diversity in mycobacterium celatum strains caused by presence of two different copies of 16s rrna gene. | direct sequencing of the 16s rrna gene (16s rdna) of mycobacterium celatum isolates showed ambiguities, suggesting heterogeneity. cloned 16s rdna yielded two copies of the gene, which differed by insertion of a thymine at position 214 and by additional mismatches. restriction fragment length polymorphism analysis confirmed the presence of two copies of 16s rdna within the bacterial chromosome. | 1998 | 9620415 |
| fatal pulmonary infection with mycobacterium celatum in an apparently immunocompetent patient. | mycobacterium celatum is a recently described mycobacterium isolated from patients who have suppressed cell-mediated immunity, such as aids. we present here, to our knowledge, the first report of a fatal pulmonary infection caused by m. celatum in a 73-year-old immunocompetent female patient. the mycobacterium was identified by a 16s rrna sequence analysis. | 1998 | 9466784 |
| utility of high-performance liquid chromatography for identification of mycobacterial species rarely encountered in clinical laboratories. | high-performance liquid chromatography (hplc) has been demonstrated to be a suitable technique for determining the species of mycobacteria on the basis of their mycolic acid pattern. representative hplc profiles, which are needed for the visual recognition of chromatograms, have been published for the most frequently encountered mycobacterial species. no extensive study has been reported for less common species, and only a few, scattered chromatographic patterns are available in literature. this ... | 1995 | 7614969 |
| false-positive results for mycobacterium celatum with the accuprobe mycobacterium tuberculosis complex assay. | mycobacterium celatum type 1 was found to cross-react in the accuprobe mycobacterium tuberculosis complex assay. subsequently, we found a statistically significant increase in the relative light units with lower temperatures, suggesting that it is necessary to perform this accuprobe assay at between 60 and 61 degrees c. we also recommend the inclusion of m. celatum type 1 as a negative control. | 2000 | 10878076 |
| isolation of mycobacterium celatum from patients infected with human immunodeficiency virus. | mycobacterium celatum is a recently described, slowly growing mycobacterium of still undefined clinical relevance. a retrospective study of seven patients was conducted to further elucidate the clinical presentation and prognosis of infection due to m. celatum in patients with aids. three patients had an exclusively pulmonary infection and 3 had disseminated infection (including 2 patients with pulmonary and extrapulmonary involvement), and 1 patient had an exclusively extrapulmonary disease. fe ... | 1997 | 9114138 |
| mycobacterium celatum pulmonary infection. | | 2003 | 14696823 |
| mycobacterium celatum, an emerging pathogen and cause of false positive amplified mycobacterium tuberculosis direct test. | mycobacterium celatum is a recently described organism. herein we describe a case of m. celatum lymphadenitis in an immunocompetent child and the first reported case of a m. celatum infection (lung abscess) in a transplant recipient. a literature review identified 19 other cases of m. celatum infection. fifteen occurred in patients with the acquired immunodeficiency syndrome. of these, nine were disseminated and six were localized (primarily to the lungs). the remaining 4 patients were immunocom ... | 2004 | 15135495 |
| a case of pulmonary mycobacterium celatum in an indian aids patient. | | 2005 | 15603997 |
| pulmonary mycobacterium celatum immune restoration disease: immunopathology and response to corticosteroid therapy. | | 2005 | 16260918 |
| disseminated mycobacterium celatum infection in a white-tailed trogon (trogon viridis). | an adult female white-tailed trogon (trogon viridis) was presented with abdominal enlargement and hard subcutaneous masses. necropsy findings included bony masses extending from skeletal structures, disseminated pale foci in the liver, and a pale mass in the kidney. histological examination revealed multifocal to coalescing granulomatous inflammation in the bone, liver, kidney, lung and spleen. mycobacterium celatum was isolated from the liver and identified by dna sequencing. this is the first ... | 2006 | 16854645 |
| the organization of two rrna (rrn) operons of the slow-growing pathogen mycobacterium celatum provides key insights into mycobacterial evolution. | the slow-growing mycobacterium celatum is known to have two different 16s rrna gene sequences. this study confirms the presence of two rrn operons and describes their organization. one operon (rrna) was found to be located downstream from mura and the other (rrnb) was found downstream from tyrs. the promoter regions were sequenced, and also the intergenic transcribed spacer (its1 and its2) regions separating the 16s rrna, 23s rrna and 5s rrna gene coding regions. analysis of the rna fraction rev ... | 2008 | 18248431 |
| mycobacterium celatum pulmonary infection mimicking pulmonary tuberculosis in a patient with ankylosing spondylitis. | mycobacterium celatum, a slow-growing acid-fast bacillus, is an uncommon cause of human infection, mainly occurring in patients with aids. rarely, infections restricted to the lung and lymph nodes have been reported in immunocompetent hosts. we report herein a case of m. celatum pulmonary infection that mimicked pulmonary tuberculosis in a patient with ankylosing spondylitis. the literature was reviewed and clinical features of eight hiv-negative patients with m. celatum infection are discussed. ... | 2009 | 19269205 |
| the first report of mycobacterium celatum isolation from domestic pig (sus scrofa domestica) and roe deer (capreolus capreolus) and an overview of human infections in slovenia. | mycobacterium celatum, a slowly growing potentially pathogenic mycobacterium first described in humans, is regarded as an uncommon cause of human infection, though capable of inducing invasive disease in immunocompromised hosts. according to some reports, a serious disease due to m. celatum may also occur in individuals with no apparent immunodeficiency. in animals, an m. celatum-related disease has been described in three cases only: twice in a domestic ferret (mustela putorius furo) and once i ... | 2011 | 21647336 |
| mycobacterium fragae sp. nov., a non-chromogenic species isolated from human respiratory specimens. | three isolates of a slow-growing, non-chromogenic mycobacterium were grown from three sputum samples of a patient from the north-eastern ceará state in brazil. identification at species level could not be obtained with pcr restriction analysis of the hsp65 gene. in order to characterize the isolates we carried out phenotypic and genotypic tests. we sequenced the nearly complete 16s rrna gene and obtained partial sequences of the hsp65 (encoding the hypervariable region of the 65 kda heat-shock p ... | 2012 | 23264503 |
| a case of false-positive mycobacterium tuberculosis caused by mycobacterium celatum. | mycobacterium celatum is a nontuberculous mycobacterium shown to cause symptoms similar to pulmonary m. tuberculosis. certain strains have been shown to cross-react with the probes used to detect m. tuberculosis, making this a diagnostic challenge. we present a 56-year-old gentleman who developed signs and symptoms of lung infection with computed tomography scan of the chest showing right lung apex cavitation. serial sputum samples were positive for acid-fast bacilli and nucleic acid amplificati ... | 2016 | 27895946 |
| isolation of mycobacterium kumamotonense from a patient with pulmonary infection and latent tuberculosis. | mycobacterium kumamotonense is a novel, slow-growing non-chromogenic nontuberculous mycobacterium, which belongs to mycobacterium terrae complex. we report, for the first time in greece, the isolation of m. kumamotonense from an immunocompetent patient with pulmonary infection and latent tuberculosis. m. kumamotonense was identified by sequencing analysis of 16s rdna and 65-kda heat shock protein genes while by commercial molecular assays it was misidentified as mycobacterium celatum. antibiotic ... | 2016 | 27080783 |
| notice of retraction: pulmonary mycobacterium celatum in an immunocompetent patient successfully treated with antimicrobial chemotherapy. | | 2014 | 25091758 |
| disseminated mycobacterium celatum disease with prolonged pulmonary involvement. | mycobacterium celatum is a rare cause of human infection, causing disseminated disease in immunosuppressed individuals. infections localized to the lungs and the lymph nodes have also been reported in immunocompetent individuals. the existing literature on the subject is limited as are experiences with treatment regimens and durations. in the case presented herein, two different treatment regimens were applied to an immunocompromised hiv-negative patient with primary skin involvement and extensi ... | 2014 | 25008771 |
| congenital cystic adenomatoid malformation in adulthood complicated by mycobacterium celatum infection. | a 25-year-old woman with no underlying disease presented with a large fluid-filled cavitary lesion in the right lung. mycobacterium celatum was isolated from the cavitary fluid, and treatment with ethambutol, rifampicin, and clarithromycin was initiated. after 4 months of treatment, right lower pulmonary lobectomy was performed. histological examination confirmed m. celatum infection as well as concurrent congenital cystic adenomatoid malformation (ccam). m. celatum has been implicated in opport ... | 2012 | 22892504 |
| mycobacterium celatum skin infection with sporotrichoid spread in an hiv-negative immunocompromised man. | | 2012 | 22583731 |
| mycobacterium kyorinense sp. nov., a novel, slow-growing species, related to mycobacterium celatum, isolated from human clinical specimens. | a novel, non-pigmented, slow-growing mycobacterium was identified on the basis of biochemical and nucleic acid analyses, as well as growth characteristics. three isolates were cultured from clinical samples (two from sputum and one from pus in lymph nodes) obtained from three immunocompetent patients with infections. bacterial growth occurred at 28-42 degrees c on middlebrook 7h11-oadc agar. the isolates showed negative results for tween hydrolysis, nitrate reductase, semiquantitative catalase, ... | 2009 | 19502312 |
| successful treatment of mycobacterium celatum pulmonary disease in an immunocompetent patient using antimicobacterial chemotherapy and combined pulmonary resection. | mycobacterium celatum is a nontuberculous mycobacterium that rarely causes pulmonary disease in immunocompetent subjects. we describe the successful treatment of m. celatum lung disease with antimicobacterial chemotherapy and combined pulmonary resection. a 33-year-old woman was referred to our hospital with a 3-month history of a productive cough. her medical history included pulmonary tuberculosis 14 years earlier. her chest x-ray revealed a large cavitary lesion in the left upper lobe. the sp ... | 2010 | 20879072 |
| detection and molecular characterization of mycobacterium celatum as a cause of splenitis in a domestic ferret (mustela putorius furo). | mycobacterium celatum is a slow growing non-tuberculous mycobacterium described mainly as occurring in human patients. only two cases of infection with this pathogen have been reported previously in animals. a 5-year-old, neutered male ferret was presented with progressive weight loss and muscle atrophy. pale mucous membranes, slight alopecia of the tail and splenomegaly, confirmed by abdominal ultrasound, were observed. fine-needle aspirations of the spleen revealed extramedullary haematopoiesi ... | 2010 | 20880545 |
| risk for mycobacterium celatum infection from ferret. | | 2011 | 21392459 |
| first isolation of mycobacterium kyorinense from clinical specimens in brazil. | in this article, the first isolation of mycobacterium kyorinense specimens in brazil is described. m. kyorinense is a recently identified species, with a few strains reported only in japan. the brazilian isolates were initially identified as mycobacterium celatum by pcr restriction enzyme pattern analysis (pra) with hsp65. however, biochemical tests indicated the same profile of m. kyorinense and distinguished them from m. celatum and mycobacterium branderi. the sequencing of the hsp65, rpob, an ... | 2012 | 22518856 |
| virulence and drug susceptibility of mycobacterium celatum. | the virulence and drug susceptibility of a clinical isolate of mycobacterium celatum which showed smooth transparent (st) and smooth opaque (so) colonies were studied. while st cells multiplied intracellularly and maintained their coccobacillary form in a human macrophage model of infection, so cells formed long filaments and completely destroyed the phagocytes. in balb/c mice, the st variant, but not the so variant, grew efficiently in the spleen, liver and lung. the st variant was usually more ... | 2000 | 11065352 |
| mycobacterium celatum infection in a patient with aids. | | 1998 | 9455576 |
| comparison of a new insertion element, is1407, with established molecular markers for the characterization of mycobacterium celatum. | genomic analyses of 18 mycobacterium celatum strains obtained from different patients in three countries (united states, united kingdom, and france) were performed; the methods used in this study were restriction fragment length polymorphism (rflp) analysis, pulsed-field gel electrophoresis (pfge) analysis, and pcr restriction analysis (pra) of the hsp-65 gene. a new insertion sequence, is1407 (genbank accession no. x97307), belonging to the is256 family, was identified in m. celatum type 1 stra ... | 1997 | 9226894 |