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continuous light abolishes the maternal entrainment of the circadian activity rhythm of the pups in the field mouse.12:12-h cycles of presence and absence of mother mouse act as a 'zeitgeber' and entrain the circadian rhythm of locomotor activity in the pups of mus booduga under continuous darkness or continuous dim light. continuous higher illumination of 15-25 lx abolishes this impressive maternal entrainment.19873582578
entrainment of the circadian rhythm in the locomotor activity of mus booduga by red and white light.the role of red light (greater than 610 nm) and white incandescent light in entraining the circadian locomotor activity rhythm of the field mouse mus booduga has been studied using different light intensities. red light of less than 150 microw/cm2 caused negative masking and greater than 150 microw/cm2 caused entrainment. such intensity dependent masking and entrainment were also obtained with white incandescent light.19853850025
encephalomyocarditis virus activity in mus booduga (gray) in barur village (1961-1962), sagar kfd area, mysore state, india. 19734357094
effect of the scorpion, heterometrus fulvipes venom on mg2+ atpase activity in the mouse, mus booduga. 19836136462
laboratory trials of three anticoagulant rodenticides for use against the indian field mouse, mus booduga gray.the efficacy of three anticoagulant rodenticides for use against the indian field mouse, mus booduga, was evaluated in the laboratory. the poisons, namely warfarin, bromadiolone and brodifacoum, were all found to be toxic enough at the concentrations normally used against other commensal and field rodents. with brodifacoum (0.001 25%), bromadiolone (0.005%) and warfarin (0.025%), 83% of the animals died respectively after 1, 1 and 6 days' feeding. it is suggested that brodifacoum and bromadiolon ...19846512257
circadian rhythmicity in aminotransferases in the indian field mouse mus booduga gray. 19807203545
laboratory evaluation of bait base for the control of indian field mouse, mus booduga (gray).species specific bait evaluation is important for the successful control of rodent populations through rodenticides. experiments were conducted on the bait preference of indian field mouse, m. booduga. results reveal that rice normal grain, rice cracked grain, rice +4% coconut oil and millet +2% coconut oil may be used as effective poison carriers for the indian field mouse. additives like oil, sugar and salt did not improve the palatability of bait materials.19957590958
light-induced phase response curves of the circadian activity rhythm in individual field mice, mus booduga.the circadian rhythm of locomotor activity of the field mouse mus booduga was studied and single animal phase response curves (prcs) (n = 8) were constructed for 15-min daylight pulses of 1000 lux intensity. the light pulses, presented at different phases of the circadian cycle, evoked advancing and delaying phase shifts (delta phi s) depending on the circadian time (ct) of light pulse application. delta phi s by light pulses applied at the same phase are strongly correlated with the animals' ci ...19968974186
precision of a mammalian circadian clock.this paper reports study of day-to-day instability in the locomotor activity rhythm of the nocturnal field mouse mus booduga. the free-running period (tau) of this rhythm was estimated in constant darkness in n = 347 adult male mice. the "onset" and "offset" of locomotor activity rhythm were used as phase markers of the circadian clock. the precision of the onset of locomotor activity was observed to be a non-linear function of tau, with maximal precision at tau close to 24 h. the precision of t ...199910451856
chromosomal and molecular divergence in the indian pygmy field mice mus booduga-terricolor lineage of the subgenus mus.mus booduga and mus terricolor both have 2n = 40. unlike m. booduga, with all acrocentric chromosomes, m. terricolor invariably has large submetacentric x and acrocentric y due to an increase of heterochromatin. in contrast to the conservative karyotype of the co-existing sibling species booduga, three chromosome types of terricolor are found in different populations and their divergent karyotypes have autosomal heterochromatin variations established in the homozygous condition. the average gene ...19969081861
responses of the circadian locomotor activity rhythm of mus booduga to shifts in ld schedules.the responses of the field mouse mus booduga to shifts in schedules of ld cycles were monitored and the results were interpreted with the help of a prc constructed for the same species. the results reveal that, m. booduga reentrained faster with a lesser number of transients after delay shifts than advance shifts, thus exhibiting "asymmetry effect." a positive correlation was observed between the number of transients and the number of hours of shift. in most of the shifts, the sign of the transi ...19968877119
intensity-dependent phase-adjustments in the locomotor activity rhythm of the nocturnal field mouse mus booduga.the locomotor activity rhythm of the nocturnal field mouse mus booduga was monitored under constant darkness (dd) and free-running periods (tau) were estimated. following a free-run of about 15 days in dd, the animals were exposed to periodic light pulses (lps) of various intensities (1 lux, 10 lux, 50 lux, 100 lux, and 1,000 lux) and 15 minutes duration for 65 days at intervals of 24 hours to investigate the influence of intensity of light on the phase-angle-difference (psi) between the onset o ...200211857479
green light evokes maximum phase shifts in the locomotor activity rhythm of the field mouse mus booduga.the effect of pulses of different monochromatic light wavelengths was investigated on the circadian locomotor activity rhythm of the tropical rodent mus booduga. blue (480 nm), green (549 nm) and red (649 nm) light were used for pulses at circadian time (ct) 14 and 20, the maximum delay and advance eliciting phases of the white light phase response curve (prc). all three wavelengths evoked qualitatively similar responses in terms of the signs of the phase shifts. contrary to the results obtained ...19968786463
catalytic potential of field mouse mus booduga brain acetylcholinesterase during repeated hexachlorophene treatment.the catalytic efficiency of the field mouse (mus booduga) brain acetyl cholinesterase (ache, ec 3.1.1.7) was significantly (p less than 0.001) decreased probably through the reduction in the active site density of the enzyme content and elevation in the activation energy (delta e) requirements during repeated hexachlorophene (hcp) treatment. fall in the activity potential of ache may account for the interference of hcp or its reactive metabolites with the acetylcholine (ach)-ache system and dese ...19846506093
impact of scorpion heterometrus fulvipes venom on cholinesterase rhythmicity in the tropical mouse mus booduga.rhythmicities of acetylcholine (ach) and acetylcholinesterase (ache) were studied in the mouse, mus booduga (gray), following intramuscular injection of scorpion, heterometrus fulvipes (c. koch) venom. envenomation inhibited the activity levels of ach and ache in all the tissues selected for experimentation. control animals exhibited diel rhythmicity in ach and ache while envenomated animals showed fluctuation in the phase (delta phi), amplitude (a), acrophase (phi) and the extreme activity hour ...19846490130
cycles of presence and absence of mother mouse entrain the circadian clock of pups.recent findings on neural and endocrine rhythms in infant mice and rats show that maternal coordination has an important role in setting the phase of the developing circadian clock both in the fetus and soon after birth. however, less information is available about the influence of the mother on activity/rest cycles of infants. separation of the mother from infants in guinea pigs, monkeys and rats results in an increase in sleep disturbance (enhanced activity?). in this context it may be a commo ...19854047172
changes in hepatic carbohydrate metabolism of the mouse, mus booduga (gray), by hexachlorophene treatment. 19873814845
absence of extraretinal photic entrainment in a diurnal squirrel (funambulus palmarum) and a nocturnal mouse (mus booduga). 19863570374
presence-absence cycles of the mother and not light-darkness are the zeitgeber for the circadian rhythm of newborn mice.the relative roles of conflicting zeitgebers [presence/absence (pa) cycles versus light/dark (ld) cycles] on entrainment of circadian rhythm of locomotor activity were tested in pups of the night active mouse mus booduga. during the early days of the pups' life the pa cycles of the mother acted as a zeitgeber and entrained their activity rhythm, even though the ld cycles were available. entrainment by ld cycles took place only when the pups' eyes opened and probably became functional.19892707377
effect of dieldrin on catalytic potential of field mouse mus booduga brain acetylcholinesterase.substrate kinetics of acetylcholinesterase (ache) were investigated in control and dieldrin-treated mus booduga brains. non competitive inhibition with respect to activation by acetylcholine was indicated by decreased maximal velocity (v) without change in michaelis-menten constant (km). activation energies (delta e) were found to be increased suggesting decreased efficiency of enzyme in dieldrin-treated mouse brains. fall in the activity potential of ache may account for the interference of die ...19872444176
comparative dimensional characteristics of spermatozoa in muridae.a comparative study has been made of the dimensional characteristics in six species of muridae (malardia meltada, bandicota bengalensis, albino rat, rattus norvegicus, mus booduga, rattus rattus). characteristic differences were found in the dimensions of their spermatozoa. head dimensions viz., acrosome length, width, area and post-acrosomal area, vary significantly between different species but the differences are significant within individuals of the same species. flagellum dimensions viz., m ...1977615418
suppression of oestrus-inducing pheromone production in the indian field mouse, mus booduga gray, by treatment with an antiandrogen.the effect of cyproterone acetate (ca) on the production of the male-originating oestrus-inducing pheromone in the indian field mouse, mus booduga gray was investigated. the anoestrus induced in regularly cycling females by unisexual grouping was reversed by exposure to intact males. the majority of male-exposed females returned to oestrus within seven days, with a peak on the fourth-day. by contrast, exposure to ca-treated males failed to induce oestrus in grouped females. since ca is a potent ...1979574450
irradiance dependency of uv-a induced phase shifts in the locomotor activity rhythm of the field mouse mus booduga.in the nocturnal field mouse mus booduga, the responsiveness of the circadian system to uv-a light of 2.5 w/m2 and 30 minutes duration is known to be phase dependent. the results of our experiments indicate that the phase shifts evoked by uv-a at the two phases, ct14 (circadian time 14) and ct20 increases nonlinearly with irradiance.200011128294
effects of restricted feeding cycle on the locomotor activity rhythm in the mouse mus booduga.the effect of restricted feeding (rf) cycles on the circadian locomotor activity rhythm was studied in the nocturnal field mouse mus booduga. mice were presented with a 2-h meal schedule every 24 h in continuous darkness (dd), in continuous light (ll), and in a light-dark (ld) cycle. additionally, in dd, two groups of mice were subjected to rf cycles of periodicities 22 (t22) and 26 h (t26), respectively, in order to assess the limits of entrainment. the t22 and t26 rf cycles failed to produce a ...200010978481
probing the circadian oscillator of a mammal by two-pulse perturbations.when organisms are maintained under constant conditions of light and temperature, their endogenous circadian rhythms free run, manifesting their intrinsic period. the phases of these free-running rhythms can be shifted by stimuli of light, temperature, and drugs. the change from one free-running steady state to another following a perturbation often involves several transient cycles (cycles of free-running rhythm drifting slowly to catch up with the postperturbation steady state). although the i ...200010757458
diazepam modulates the period of locomotor rhythm in mice (mus booduga) and attenuates light-induced phase advances.experiments were carried out on the continuous action of diazepam (benzodiazepine) offered through drinking water in 2% ethanol on psi and tau of the activity rhythms under ld (12:12) and dd conditions. under entraining conditions diazepam failed to evoke striking changes in psi. on the other hand, under free-running conditions period-lengthening and period-shortening effects were observed. further experiments conducted on the continuous effect of diazepam on light pulse evoked phase shifts reve ...19968743600
protein metabolism in brain and muscle tissues of mus booduga following repeated oral benzenehexachloride feeding.protein metabolism was studied in the brain and muscle tissues of mice, mus booduga after administering orally 50 mg/kg body weight of benzenehexachloride (bhc) daily for 1, 5 and 15 days. both tissues exhibited considerable decline in all the protein fractions such as total, soluble and structural proteins. this corroborates with the increased levels of free amino acids (faa) and protease. to fortify these alterations, elevation in the activities of aspartate aminotransferase (aat), alanine ami ...19947526602
probing the circadian pacemaker of a mouse using two light pulses.in two separate sets of experiments, the phases of the locomotor activity rhythm of the nocturnal field mouse mus booduga were probed using two light pulses (lps). in the first set of experiments, the circadian pacemaker underlying the locomotor activity rhythm was perturbed at circadian time 14 (ct 14) using a resetting light pulse lp1 of 1000 lux intensity and 15 min duration. the phases of the resetting pacemaker were then probed at all even cts between ct 16 and ct 14 using a prc probing lig ...200010677018
in the field mouse mus booduga melatonin phase response curves (prcs) have a different time course and wave form relative to light prc.the phase shifting effects of the pineal hormone melatonin on the circadian locomotor activity rhythm of the field mouse. mus booduga was examined at various phases of the circadian cycle using single melatonin injections of two concentrations (10 mg/kg, high dose; and 1 mg/kg, low dose) and two phase response curves (prcs) were constructed. a single dose of melatonin administered during the early subjective day evoked maximum phase delays, and during the late subjective night evoked phase advan ...199910231728
timely administration of melatonin accelerates reentrainment to phase-shifted light-dark cycles in the field mouse mus booduga.the effect of melatonin on the rate of reentrainment after a 6 h phase delay and a 6 h phase advance in the light-dark (ld) cycle was assayed in the nocturnal field mouse mus booduga. after a phase delay of 6 h in the ld cycle, a single dose of melatonin (1 mg/kg) was administered for three consecutive days at about ct4 (circadian time 4). after a phase advance of 6 h in the ld cycle, melatonin was administered for three consecutive days at about ct22. melatonin was found to accelerate reentrain ...199910219488
role of constitutive heterochromatin in evolutionary divergence: results of chromosome banding and condensation inhibition studies in mus musculus, mus booduga and mus dunni. 198328563313
ultraviolet light-induced phase response curve for the locomotor activity rhythm of the field mouse mus booduga. 199910084152
relationship between light intensity and phase resetting in a mammalian circadian system.the light-induced phase-resetting response of the locomotor activity rhythm in the field mouse mus booduga was studied at two phases of the circadian cycle known to respond to light stimuli of 15 min duration and 1000 lux intensity with maximum advance (at circadian time 20 [ct20]) and maximum delay phase-shifts (at ct15). the phase-shifts evoked by natural daylight stimuli of various illuminations ranging between 0.001 lux and 10,000 lux and lasting 15 min were estimated. the results clearly de ...19999919688
ultraviolet-light-evoked phase shifts in the locomotor activity rhythm of the field mouse mus booduga.the circadian rhythm of locomotor activity in the nocturnal field mouse mus booduga has been monitored after an exposure to ultraviolet-a (uv-a; wavelength between 350 and 400 nm) radiation at various hours of the subject's cycle. the magnitude of the phase shift is used to determine the sensitivity of the circadian pacemaker underlying locomotor activity rhythm. it is observed that uv-a shifts the phase of the locomotor activity rhythm in a phase-dependent manner. a phase response curve (prc) i ...19989868798
age-dependent modulation of circadian parameters in the field mouse mus booduga.the locomotor activity of the field mouse mus booduga was monitored under continuous darkness (dd) for extended periods of 275 to 388 days. free-running period (tau), activity time (alpha) and rest time (rho) were computed from the activity records for all the animals (n = 10). decreases in the circadian period (tau) with age were observed in some of the animals at an early age (< ca. 100 days) and then tau remained relatively constant for rest of their life span. the activity time (alpha), rest ...19989503653
rapid phase resetting of a mammalian circadian rhythm by brief light pulses.the phase-shift (delta phi) responses of the circadian rhythm in the field mouse mus booduga to brief light pulses (lps) of 15 minutes duration and 1000 lux intensity were measured in 90 experiments. in each experiment, a resetting light pulse lp1 was administered at ct14 (ct, circadian time), and a scanning light pulse lp2 was then variously administered in separate experiments at ct16, ct20, and ct22 in the same and in the next circadian cycle. the delta phi obtained in all these two-pulse exp ...19979360021
relationship between free-running period and minimum tolerable light pulse interval of skeleton photoperiods in field mice mus booduga.the entrainment of the circadian rhythm of locomotor activity was studied in the field mouse mus booduga in order to examine the relationship between the free-running period (tau) and minimum tolerable light pulse interval of the skeleton photoperiods. the animals were entrained under three different light/dark (ld) schedules, each out of phase with the other. they were then subjected to various skeleton photoperiods created by two repeated light pulses (lps) interrupting darkness. animals that ...19979167884
biochemical genetics of indian pygmy field mice: superoxide dismutase (sod-1) as a diagnostic marker in mus booduga. 19969126672
dynamic of nucleolus organizer regions and karyotype evolution in indian pygmy field mice.ag-nor staining and fluorescence in situ hybridization with rdna probes showed an unusually high number of nors in the indian pygmy field mice, mus booduga and the m. terricolor complex. the chromosomal location of the nors was also altered in terricolor, they were shifted from the proximal regions of the long arms to the tips of the perceptible heterochromatic short arms of the acrocentric autosomes. the results suggested dispersion of the nors in the booduga-terricolor lineage probably by tran ...200011173829
entrainment of circadian locomotor activity rhythm of the nocturnal field mouse mus booduga using daily injections of melatonin.in this paper, we report the effects of daily injections of melatonin on the locomotor activity rhythm of the nocturnal field mouse mus booduga. the locomotor activity rhythm of 45 animals was first monitored in constant darkness (dd) of the laboratory for about 15 days. the animals were then divided into three groups (experimental, vehicle-treated control, and the nontreated control groups) and subjected to three different treatments. the animals from the experimental group (n=19) were administ ...200312589688
effect of light intensity on the phase and period response curves in the nocturnal field mouse mus booduga.the effect of light intensity on the phase response curve (prc) and the period response curve (taurc) of the nocturnal field mouse mus booduga was studied. prcs and taurcs were constructed by exposing animals free-running in constant darkness (dd), to fluorescent light pulses (lps) of 100 lux and 1000 lux intensities for 15 min duration. the waveform of the prcs and taurcs evoked by high light intensity (1000 lux) stimuli was significantly different compared to those constructed using low light ...200312723882
melatonin enhances the sensitivity of circadian pacemakers to light in the nocturnal field mouse mus booduga.the effect of exogenous melatonin (1 mg/kg) on light pulse (lp) induced phase shifts of the circadian locomotor activity rhythm was studied in the nocturnal field mouse mus booduga. three phase response curves (prcs: lp, control, and experimental) were constructed to study the effect of co-administration of light and melatonin at various circadian times (cts). the lp prc was constructed by exposing animals free-running in constant darkness (dd) to lps of 100-lux intensity and 15-min duration, at ...200312945752
differential organization of a line-1 family in indian pygmy field mice.southern blot hybridization analysis of genomic dnas digested with restriction endonuclease ecor i and ava ii from mus musculus domesticus, mus booduga and mus terricolor with a cloned repetitive dna fragment of mus booduga as a probe showed difference in restriction pattern of this dna in these three species. further southern analysis of the bamh i digested genomic dnas from these species hybridized with cloned dna fragment as a probe and sequencing of the cloned dna revealed that this 252 bp c ...200315267136
temporal, spatial, and ecological modes of evolution of eurasian mus based on mitochondrial and nuclear gene sequences.we sequenced mitochondrial (cytochrome b, 12s rrna) and nuclear (irbp, rag1) genes for 17 species of the old world murine genus mus, drawn primarily from the eurasian subgenus mus. phylogenetic analysis of the newly and previously available sequences support recognition of four subgenera within mus (mus, coelomys, nannomys, and pyromys), with an unresolved basal polytomy. our data further indicate that the subgenus mus contains three distinct 'species groups': (1) a mus booduga species group, al ...200415522792
burrow characteristics of the co-existing sibling species mus booduga and mus terricolor and the genetic basis of adaptation to hypoxic/hypercapnic stress.the co-existing, sibling species mus booduga and mus terricolor show a difference in site-preference for burrows. the former build them in flat portion of the fields while the latter make burrows in earthen mounds raised for holding water in cultivated fields. in northern india which experiences great variation in climatic condition between summer and winter, m. booduga burrows have an average depth of 41 cm, as against 30 cm in southern india with less climatic fluctuation.m. terricolor burrows ...200919358716
environmental enrichment reduces anxiety by differentially activating serotonergic and neuropeptide y (npy)-ergic system in indian field mouse (mus booduga): an animal model of post-traumatic stress disorder.exposure to a predator elicits an innate fear response and mimics several behavioral disorders related to post-traumatic stress disorder (ptsd). the protective role of an enriched condition (ec) against psychogenic stressors in various animal models has been well documented. however, this condition has not been tested in field mice in the context of ptsd. in this study, we show that field mice (mus booduga) housed under ec exhibit predominantly proactive and less reactive behavior compared with ...201526016844
effect of melatonin on antioxidant status and circadian activity rhythm during hepatocarcinogenesis in mice.alteration of circadian systems can cause cancer and affects its development and response to therapeutics. the present study investigates whether cancer can disrupt circadian locomotor rhythms and evaluated the influence of melatonin (mlt) and oxaliplatin on the levels of antioxidants and circadian locomotor activity rhythms in n-nitrosodiethylamine (ndea)-induced liver tumor in indian field mouse (mus booduga).201525579551
relationship between period and phase angle differences in mus booduga under abrupt versus gradual light-dark transitions. 19989618689
purification and kinetic properties of mus booduga (gray) hepatic arginase.hepatic l-arginase from the mus booduga (gray) was purified and its kinetic characteristics were investigated. the enzyme was not adsorbed on deae-cellulose, but was retained on cm-cellulose column at ph 7.2. the michaelis-menten constant was 8.3 mm for l-arginine and was independent of ph in the range of 7.5-10.5. l-arginine concentrations as high as 0.4 m did not exert substrate inhibition in the ph range 7.4-10.0. manganese was required at a concentration of 0.05 m for full activation of the ...19979502047
changes in the carbohydrate metabolism in the selected tissues of mus booduga gray after bhc treatment.adult mice, mus booduga were fed orally with bennzenehexachloride (bhc) at a dose of 50 mg/kg body weight every day for 1, 5 and 15 days. significant decrease in the pyruvate content was observed at all periods of treatment. in support of this increase in lactate content and lactate dehydrogenase (ldh) activity was noticed in all the three tissues. enzymes of tca cycle namely isocitrate dehydrogenase (icdh), succinate dehydrogenase (sdh) and malate dehydrogenase (mdh) were inhibited suggesting a ...19911723596
histopathological changes in liver and kidney of mus booduga following oral benzenehexachloride (bhc) feeding. 19892469506
changes in the protein metabolism in liver and kidney of mus booduga gray after oral bhc feeding. 19882466502
serological evidence of thailand orthohantavirus or antigenically related virus infection among rodents in a chronic kidney disease of unknown etiology endemic area, girandurukotte, sri lanka.we have reported high seroprevalence to thailand orthohantavirus (thaiv) or thaiv-related orthohantavirus (trhv) among patients with chronic kidney disease of unknown etiology in girandurukotte, sri lanka. thaiv or trhv infection is considered to be transmitted by rodent hosts in this area, but its reservoir rodents have not yet been identified. hence, 116 rodents were captured, and seroprevalences were examined by indirect immunofluorescent antibody assay (immunofluorescence assay [ifa]) using ...201931339833
environmental enrichment enhances sociability by regulating glutamate signaling pathway through gr by epigenetic mechanisms in amygdala of indian field mice mus booduga.environmental enrichment (ee) dynamically regulates gene expression and synaptic plasticity with positive consequences on behavior. the present study was performed on field-mice to explore the effects of ee on both captive-condition inducing social stress and epigenetic changes of molecules resilience stress. for this purpose, field-mice were caught and allowed to habituate in standard laboratory conditions for 7 days. the next day animals were randomly assigned to three groups: i) mice at short ...202033017584
environmental enrichment modulates glucocorticoid receptor expression and reduces anxiety in indian field male mouse mus booduga through up-regulation of microrna-124a.enriched environmental condition (ec) has been known to reduce anxiety. in this study, we examined whether an ec could enhance anxiolytic behavior in the indian field mouse mus booduga by down-regulating the expression of glucocorticoid receptor (gr) through microrna-124a. wild individuals were captured at agricultural field, and then housed at standard conditions (sc) for 7days. after short-term at standard condition (stsc), on 8th day they were divided into three groups as those: (i) stsc mice ...201424457250
environmental enrichment upregulates micro-rna-183 and alters acetylcholinesterase splice variants to reduce anxiety-like behavior in the little indian field mouse (mus booduga).environmental enrichment (ee) has an influential role in reducing behavioral reactivity to stress. we previously observed that ee reduces the anxiety-like behavior in the field mouse mus booduga accompanied by a reduction in the expression of molecules involved in the stress pathway. in this study, we demonstrate the effect of different housing condition on regulation of micro-rna-183-sc35-mediated splicing of acetylcholinesterase (ache). adult male m. booduga were captured from an agricultural ...201323184316
circadian phase and period responses to light stimuli in two nocturnal rodents.we report period response curves (taurc) for two nocturnal murid species from india, mus booduga and mus platythrix. we further discuss the method of phase shift estimation in the presence of tau-changes, because such changes pose a serious methodological problem in the estimation of phase shifts. although the taurc indicates that most of the phase shifts are associated with small changes in tau, the period changes across all the phases showed a significant positive correlation with the phase sh ...200212182494
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