| nucleotide sequence identifies vilyuisk virus as a divergent theiler's virus. | the vilyuisk virus, originally thought to be the cause of a degenerative neurological disease of inhabitants of siberia, has been characterized by sequence analysis of its 5' noncoding and coat protein coding regions. in the 5' noncoding, leader, and vp4 regions, the nucleotide identity between the sequences of known strains of theiler's virus and vilyuisk virus is about 90%. in the vp1-encoding region, the similarity drops to about 66% compared to the 50% similarity between sequences of theiler ... | 1992 | 1413519 |
| comparison of structural and nonstructural proteins of virulent and less virulent theiler's virus isolates using two-dimensional gel electrophoresis. | the theiler's murine encephalomyelitis viruses (tmev) are important neurotropic picornaviruses because they persist in the central nervous system (cns) and produce an inflammatory demyelinating disease in the mouse, their natural host. insight into the pathogenesis of this disease may come from studying the genetic and biochemical compositions of these viruses; therefore, in this report, the structural and nonstructural proteins specified by both highly and less virulent tmev were examined. usin ... | 1985 | 2984856 |
| characterization of vilyuisk virus as a picornavirus. | the v-1 strain of vilyuisk virus, isolated from the cerebrospinal fluid of a chronic case of encephalomyelitis in siberia and subsequently passaged 41 times in mice, was examined to determine its serological relationship to theiler's murine encephalomyelitis virus (tmev) and encephalomyocarditis (emc) virus and some physicochemical characteristics of the virion. on the basis of virion size (28 nm), icosahedral symmetry, buoyant density (1.33 g/ml), sedimentation coefficient (150s), and capsid po ... | 1983 | 6195311 |
| the growth of four human and animal enteroviruses in the central nervous systems of mice. | the pattern of cns infection of our enteroviruses, coxsackievirus a14, encephalomyocarditis (emc) virus, gdvii virus, and vilyuisk virus, was investigated. the regional sites of virus replication were correlated with pathological changes. these viruses were found to replicate and produce similar lesions in selected sites in the mouse cns during acute infection. virus antigen and histological lesions were essentially confined to the gray matter, with additional but less direct support for this be ... | 1981 | 6260909 |
| immunological characterization of vilyuisk human encephalomyelitis virus. | | 1963 | 14087883 |
| phylogenetic analysis of the species theilovirus: emerging murine and human pathogens. | the cardiovirus genus of the family picornaviridae includes two distinct species, encephalomyocarditis virus and theilovirus. we now report the complete nucleotide sequences of three theiler's murine encephalomyelitis virus (tmev) strains (to yale, tob15, and vie 415htr) and of vilyuisk human encephalomyelitis virus (vhev). this information, together with the recently reported sequences of divergent theiloviruses (theiler's-like rat virus [trv] and saffold viruses 1 and 2 [safv-1 and safv-2]), e ... | 2008 | 18815294 |
| cardioviruses are genetically diverse and cause common enteric infections in south asian children. | cardioviruses cause enteric infections in mice and rats which when disseminated have been associated with myocarditis, type 1 diabetes, encephalitis, and multiple sclerosis-like symptoms. cardioviruses have also been detected at lower frequencies in other mammals. the cardiovirus genus within the picornaviridae family is currently made up of two viral species, theilovirus and encephalomyocarditis virus. until recently, only a single strain of cardioviruses (vilyuisk virus within the theilovirus ... | 2009 | 19193786 |
| analysis of the genomic homologous recombination in theilovirus based on complete genomes. | at present, theilovirus is considered to comprise four distinct serotypes, including theiler's murine encephalomyelitis virus, vilyuisk human encephalomyelitis virus, thera virus, and saffold virus. so far, there is no systematical study that investigated the genomic recombination of theilovirus. the present study performed the phylogenetic and recombination analysis of theilovirus over the complete genomes. seven potentially significant recombination events were identified. however, according t ... | 2011 | 21923921 |
| [genetic characterization of the syr-darya valley fever virus (sdvfv) (picornaviridae, cardiovirus) isolated from the blood of the patients and ticks hyalomma as. asiaticum (hyalomminae), dermacentor daghestanicus (rhipicephalinae) (ixodidae) and ornithodoros coniceps (argasidae) in kazakhstan and turkmenistan]. | the syr-darya valley fever virus (sdvfv) was originally isolated from the blood of the patient with fever in the kyzylorda province, kazakhstan, in july 1973 and was classified to the cardiovirus genus (fam. picornaviridae). later, sdvfv was isolated from the ticks hyalomma as. asiaticum schulze et schlottke, 1929 (hyalomminae) (1 strain) and dermacentor daghestanicus olenev, 1929 (rhipicephalinae) (7 strains), collected in the floodplains of the syr-darya river and the ili river. in this paper, ... | 2016 | 25549463 |