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simian hepatitis a virus (hav) strain agm-27: comparison of genome structure and growth in cell culture with other hav strains.fragments of cdna representing greater than 99% of the entire genome of wild-type hepatitis a virus (hav) strain agm-27, isolated from an african green monkey, were obtained by the polymerase chain reaction and sequenced. comparison with other hav isolates revealed differences in the predicted amino acid sequence in functionally critical parts of the genome. comparison of the biological properties of agm-27 with those of human wild-type and cell culture-adapted hm-175 strains revealed that agm-2 ...19911649901
[the modelling of hepatitis a and of enterally transmitted non-a, non-b hepatitis (hepatitis e) in saguinus mystax tamarins].a comparative study of hepatitis infection caused by human hepatitis a virus (ms-1 strain), simian hepatitis a virus (agm-27 strain), and enterically transmitted non-a, non-b hepatitis virus (tashkent-1435 strain) was carried out. susceptibility of tamarins to the agm-27 and tashkent-1435 as well as to ms-1 strain was demonstrated. all the strains induced an acute infection characterized by serum alanine aminotransferase (alt) elevation, virus excretion and antibody response. certain differences ...19901967121
[study of human and simian hepatitis a virus isolated by an immunoenzyme method using polyclonal and monoclonal antibodies].hepatitis a viruses (hav) isolated from man and old world monkeys varied in their interaction with monoclonal antibodies (mca) in enzyme immunoassay. all human hav isolates reacted with the mca under study (hic19, h7c27, and k3-4c8), whereas the viruses isolated directly from monkeys did not react with h7c27 mca and some of them also with h1c19 mca. simian hav strains became capable of reacting with h7c27 mca and h1c19 mca after adaptation to cell culture. in tests with human and simian immune s ...19892543140
characterization of a simian hepatitis a virus (hav): antigenic and genetic comparison with human hav.pa21, a strain of hepatitis a virus (hav) recovered from a naturally infected captive owl monkey, is indistinguishable from human hav in polyclonal radioimmunoassays and cross-neutralization studies. however, cdna-rna hybridization has suggested a significant difference at the genomic level between pa21 and a reference human virus, hm175. further characterization of this unique hav was undertaken in an effort to determine the extent of genetic divergence from human hav and its relation to the co ...19892552172
the resurgence of shamonda virus, an african simbu group virus of the genus orthobunyavirus, in japan.six virus isolations were made from culicoides biting midges and blood samples of sentinel cattle in kagoshima and miyazaki prefectures, the southern part of japan, in 2002. serological and genetical tests identified these viruses as isolates of shamonda virus (shav), which belongs to the simbu group of the genus orthobunyavirus of the family bunyaviridae. initially, shav was isolated from cattle and culicoides biting midges in nigeria in the 1960s, and its presence has not been reported until t ...200515503217
simian hepatitis a virus derived from a captive rhesus monkey in india is similar to the strain isolated from wild african green monkeys in kenya.summary: a simian hepatitis a virus (hav) was identified retrospectively in a faecal sample from a rhesus monkey in india, inoculated in 1995 with a faecal suspension from a suspected patient of non-a to e hepatitis. the monkey was in captivity for 2 years in one of the experimental primate facilities in western india before being moved to the national institute of virology, pune for experimentation. phylogenetic analysis based on a partial sequence of the 5' noncoding region placed this virus i ...200919175880
molecular genetic identification of isolates of the hepatitis a virus (hav) from monkeys at adler primate center.the aim of this study was to assess prevalence and genetic variability of hepatitis a virus (hav) isolates in monkeys born and kept at adler primate center, as well as in imported animals.201829380396
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