| fatal echovirus 11 infections in outbreak in special-care baby unit. | in december, 1977, an outbreak of echovirus 11 infection occurred in the special-care baby unit of the cambridge maternity hospital. 3 neonates died, and of 24 infants on the ward during the epidemic 6 others were infected, 3 with symptoms. 3 infants had similar symptoms but virus could not be isolated. the pathological changes in the 3 fatal infections, have not previously been reported for echovirus 11; nor have fatal infections occurred in an epidemic in a special-care baby unit. | 1978 | 80644 |
| echovirus-11 infection in a special-care baby unit. | | 1979 | 84141 |
| echovirus 11 infection and intrauterine death. | | 1979 | 84142 |
| virucidal effect of alcohols against echovirus 11. | | 1979 | 85084 |
| beta-hydroxy-beta-methylglutaricaciduria, reye's syndrome, and echovirus 11. | | 1979 | 86872 |
| the relative effectiveness of commonly used disinfectants in inactivation of echovirus 11. | echovirus 11 in the presence of fetal calf serum was exposed to six commonly used disinfectants for times of 10, 20 and 30 s. at the end of such exposure times, skim milk neutralized disinfectant activity and residual virus was assayed using the plaque technique. the six disinfectants studied were javex, sodium hydroxide, ethanol, wescodyne, one stroke ves-phene, and sonacide. although 0.25% (w/v) sodium hydroxide and 95% (v/v) ethanol were equally virucidal and significantly more so than the ot ... | 1978 | 99474 |
| organ culture of human aorta: prolonged survival with support of viral replication. | organ cultures were established with use of human fetal aorta obtained after death; cellular elements were preserved in the cultures for periods of up to eight weeks, with maintenance of their in vivo tissue relationships. histologically, these cultures preserve the three coats of the aorta, including an intact endothelial layer cells. the aorta organ cultures supported the replication of echovirus 11, herpes simplex virus type 1, adenovirus 2, and coxsackievirus b5 without the production of det ... | 1975 | 165246 |
| [permissivity of mouse-man hybrid cell clones to three enteroviruses: poliovirus ii, coxsackie b3 and echovirus 11. role of human chromosome f. 19 (author's transl)]. | the permissivity of human cells to enteroviruses is linked to the presence of specific cell receptors. owing to the chance elimination of human chromosomes, the man-mouse hybrid cells may be permissive or not depending on the genome responsible for synthesis of the receptors, and whether it has been conserved or not. by comparison of the cytopathogenic effects and virus production after inoculation of the viruses polio ii, echo 11 and coxsachie b3 to various hybrid strains, we observed an identi ... | 1976 | 180477 |
| antiviral effects of amphotericin b methyl ester. | the methyl ester of amphotericin b (ame) is water soluble, retains antifungal activity, and is significantly less toxic in mammals than amphotericin b. in contrast to amphotericin b, which is not water soluble, ame exhibits antiviral effects against vesicular stomatitis virus, herpes simplex virus types 1 and 2, sindbis virus, and vaccinia virus in a plaque reduction assay. no antiviral effects could be demonstrated against the unenveloped adenovirus type 4 or echovirus type 11. the extent of vi ... | 1978 | 206201 |
| [echo-11 virus infection in a 6-month-old infant showing clinical signs of varicella]. | | 1979 | 424258 |
| the relative resistance of f2 bacteriophage to inactivation by disinfectants. | f2 bacteriophage in the presence of fetal calf serum (at a final concentration of 10%) was exposed to six commonly used disinfectants for times of 10, 20 and 30 sec. at the end of exposure times skim milk neutralized the disinfectant activity and residual virus was assayed using the plaque technique. the 6 disinfectants considered were javex, sodium hydroxide, ethanol, wescodyne, one stroke ves-phene and sonacide. a 0.25% (w/v) solution of sodium hydroxide and 1/50 javex (1200 parts/10(6) chlori ... | 1979 | 458139 |
| vesicular lesions in adults due to echovirus 11 infections. | echovirus 11 was recovered from vesicular lesions in two adults. patient 1 had a severe disseminated vesicular exanthem. patient 2 had a mild vesicular enanthem. both were clinically suspected of having herpesvirus hominis lesions. serologic studies indicate that these viruses were similar to each other and also to the "u" prime strain. | 1977 | 596902 |
| diarrheal diseases of infancy in cali, colombia: study design and summary report on isolated disease agents. | for public health reasons, it is important that the etiologic agents of early childhood diarrhea be isolated and identified, and that their routes of transmission be defined. this is especially true in tropical and subtropical developing countries, where childhood patterns of exposure to diarrheal disease agents usually differ from those in developed countries, and where diarrheal illness is a frequent harbinger of death among children under five years of age. this artical describes a study desi ... | 1976 | 974303 |
| an epidemic of echovirus 18 meningitis. | the first reported outbreak of echovirus 18 meningitis in the united states occurred during the summer of 1972 in durham, north carolina. one hundred three cases of aseptic meningitis were seen at duke university medical center over a period of four months. most of the patients were less than 25 years old, black, and residents of durham county or nearby counties.. symptoms included headache (92%), fever (76%), nuchal rigidity (67%), and nausea and/or vomiting (51%). in contrast to previously pub ... | 1975 | 1167369 |
| [proceedings: diarrhea epidemics caused by echovirus 11 in a nursery for premature infants]. | | 1975 | 1178289 |
| virologic and serologic studies on an outbreak of echovirus type 11 infection in a hospital maternity unit. | an outbreak of echovirus type 11 (e-11) infection occurred among newborn babies in a hospital maternity unit in the summer of 1971. the results of studies are as follows: 1) forty-one of 188 infants developed febrile illness with stomatitis during one and a half months from july to september. e-11 was isolated from stool specimens of 14 infants and two throat swabs. antibody response to the virus was shown in all the 19 cases examined. some of their mothers were suffering from subclinical infect ... | 1975 | 1195517 |
| detection of enteroviral rna by polymerase chain reaction in faecal samples from patients with aseptic meningitis. | an assay based on the polymerase chain reaction (pcr) for detection of enteroviral rna in stool samples was carried out using specimens from 74 patients with aseptic meningitis. the primer pair and probe were derived from the highly conserved 5' non-coding enterovirus genomic region. enteroviral rna was detected in faeces of all 36 patients in whom an enterovirus was isolated from stool. the pcr assay yielded positive results in additionally 3/6 cases where enterovirus diagnoses were obtained by ... | 1992 | 1328511 |
| intrauterine fetal death due to echovirus 11. | in a case of intrauterine fetal death in the 29th week of gestation, echovirus 11 could be isolated from the umbilical cord of the fetus. the mother had no apparent signs of infection but serological evidence of current echovirus 11 infection. enterovirus pcr performed on paraffin-embedded specimens of various tissues (myocardium, lung, liver and placenta) from the fetus yielded positive results in all cases. these findings, together with supporting serological and epidemiological findings--e.g. ... | 1992 | 1509244 |
| a 44,000 glycoprotein is involved in the attachment of echovirus-11 onto susceptible cells. | cellular receptors play an important role in viral pathogenesis. until now little was known on echovirus (ev) receptor. using detergent-treated kb cell extracts as immunogen, a mouse monoclonal antibody (mab 143) was produced that selectively blocks the attachment of ev-11 to kb and other susceptible cells. by immunoblotting, mab 143 detected a 44,000 protein on susceptible cell lines but not on cell lines from nonprimate origin. the receptor protein complex, purified from kb cell membranes by i ... | 1992 | 1604819 |
| [uveitis, caused by echo-11 virus]. | analysis of clinical manifestations of a total enteroviral infection with echo-11 virus-induced uveitis in 58 infants aged 2 weeks to 1.5 years has shown that uveitis develops on days 1-10 of the disease and is associated with a weak injection, endothelial edema, hyperemia and edema of the iris rapidly eventuating in destruction of the pigment lamina and fenestration. posterior synechiae, pupil deformations, grave uveitis with hypotonia of 4-10 mm hg are rapidly developing. a two-year follow-up ... | 1991 | 1949493 |
| echoviruses include genetically distinct serotypes. | we have studied the genetic relationships of echoviruses using nucleotide sequencing and hybridization analysis. the nucleotide sequence of the echovirus 11 (ev11) p2 and p3 regions, which encode the nonstructural proteins, was shown to resemble closely those of coxsackie b viruses (cbv) and coxsackievirus a9 (cav9). ev11, cbv and cav9 have a similar organization in the 3' non-coding region when compared to polioviruses and cav21. in contrast, the 3' end of ev22 shares only minimal sequence homo ... | 1990 | 2170575 |
| isolation and preliminary characterization of antigenic variant of echovirus type 11. | nosocomial infection with echovirus type 11 resulting in aseptic meningitis occurred among newborn babies in a hospital neonatal room at fukui city. the virus was identified as a variant of echovirus type 11 by cross-neutralization tests with antisera against the prototype gregory strain and the current fukui isolate. fukui isolates expressed strain specific antigen(s) in addition to type specific common antigen(s), but lacked a certain antigen(s) which was present in the prototype strain. sodiu ... | 1990 | 2269879 |
| viral infections and recurrences of febrile convulsions. | to determine whether complicated febrile seizures occur more often in children with a proven viral infection, we performed viral examinations on 144 children with febrile convulsions, of whom 112 had simple and 32 had complicated seizures. a diagnosis of virus infection was verified in 46% of the former patients and 53% of the latter. three adenoviruses, one parainfluenza virus type 2 and one type 3, one respiratory syncytial virus, one echovirus type 11, one herpes simplex virus type 2, and one ... | 1990 | 2299489 |
| persistent enterovirus infection in culture-negative meningoencephalitis: demonstration by enzymatic rna amplification. | chronic meningoencephalitis due to enterovirus infection can occur in patients with antibody deficiencies. a modified polymerase chain reaction technique demonstrated persistent echovirus 11 infection in such a patient, despite negative routine viral cultures and negative routine nucleic acid hybridization. although the sequence of echovirus 11 has not yet been determined, genomic conservation among the enteroviruses is significant, permitting detection of echovirus 11 with a primer pair and pro ... | 1990 | 2319170 |
| disseminated echovirus infection in a patient with multiple myeloma and a functional defect in complement. treatment with intravenous immunoglobulin. | a man with igg1 multiple myeloma developed fever, confusion, and progressive muscle weakness resulting in paralysis. echovirus type 11 was isolated from cerebrospinal fluid, pleura, pleural fluid, and muscle, and muscle biopsy disclosed changes consistent with viral myositis. immunologic evaluation revealed low serum levels of polyclonal igg subtypes 1 and 3, reduced blood levels of t-helper/inducer and t-suppressor/cytotoxic cells, and a complement abnormality involving the function of the clas ... | 1989 | 2525014 |
| conservative management of an echovirus 11 outbreak in a neonatal unit. | two babies in a neonatal unit presented on the same day with meningitis due to echovirus 11, which was thought to have been introduced by staff. at this time echovirus 11 was also isolated from the stools of eight other babies; five of them did not have signs of infection. no intervention was made except to emphasise the importance of handwashing. there was evidence of secondary spread to two babies who were both clinically well. the attack rate was twelve (29%) of forty-one babies exposed. seve ... | 1989 | 2564069 |
| handling echovirus 11 outbreaks. | | 1989 | 2566870 |
| intravenous immunoglobulin in disseminated neonatal echovirus 11 infection. | | 1989 | 2717278 |
| [echo-ii virus, the pathogen of the third outbreak of uveitis in children in kransnoyarsk, 1986]. | the third outbreak of an acute infection accompanied in 3 cases by inflammation of the uveal membrane (uveitis) was recorded among infants in krasnoyarsk in 1986. from the infants with the eye involvement as well as from those in contact with the former, 36 strains of echo-11 virus were isolated, and seroconversion to this virus was demonstrated. all the infants in contact with the eye patients were given gamma-globulin which seemed to limit the spread of the infection. the third outbreak of uve ... | 1989 | 2728407 |
| [outbreak of enteroviral uveitis in children in omsk in 1987-1988]. | from may, 1987, to july, 1988, 56 cases of acute enterovirus infection complicated by uveitis were reported in omsk, western siberia, ussr. infants aged from 15 days to 19 months were involved. the infection was nosocomial, the peak of the incidence occurring in january 1988. severe and moderately severe cases of uveitis (43 out of 56 infants) were prevalent running a course with destruction of the iris, formation of posterior synechias, deformation of the ciliary body, lenticular opacity, appea ... | 1990 | 2363274 |
| dual meningoencephalitis with echovirus type 11 and adenovirus in combined (common variable) immunodeficiency. | | 1988 | 2850526 |
| presence of insulin binding sites on viral particles. | using a standard radio-receptor assay, we have demonstrated that [125i]insulin can bind specifically to each of two types of purified enveloped viruses, influenza a virus and rous sarcoma virus. a non-enveloped icosahedral virus (echovirus 11) and herpes simplex virus type 2, which acquires its envelope from the nuclear membrane of the cell, did not possess insulin receptor activity. displacement of specifically bound radiolabelled insulin from the viral surface was achieved by addition of an ex ... | 1988 | 2851292 |
| maternal and neonatal neutralizing antibody titers to selected enteroviruses. | neutralizing antibody titers were determined at term for 98 matched mothers' serum and neonatal cord blood pairs, to coxsackieviruses b2, b3, b4 and b5 and to echovirus 11. the reciprocal of the geometric mean titers of maternal sera were, respectively, 15.3, 18.1, 53.5, 14.1 and 11.4. the geometric mean titers of cord sera were statistically lower for coxsackie b5 and echovirus 11 (p less than 0.031 and p less than 0.005, respectively) than those in maternal sera. the percentage of neonates bo ... | 1985 | 2982132 |
| direct inactivation of viruses by mcp-1 and mcp-2, natural peptide antibiotics from rabbit leukocytes. | six homologous peptides were purified to homogeneity from rabbit granulocytes or alveolar macrophages and tested for their ability to inactivate herpes simplex virus type 1 (hsv-1). two of the peptides, mcp-1 and mcp-2, showed considerable in vitro neutralizing activity, whereas four structurally homologous peptides (np-3a, np-3b, np-4, and np-5) were relatively ineffective. inactivation of hsv-1 by mcp-1 or mcp-2 depended on peptide concentration and on the time, temperature, and ph of the incu ... | 1985 | 2985808 |
| cross-reactions of immunoglobulin m and g antibodies with enterovirus-specific viral structural proteins. | we analysed the reactivity of enterovirus-specific human igm and igg antibodies with the structural proteins of different enteroviruses by the immunoblot technique. in general, all immunoglobulin g antibodies of the tested sera reacted with capsid polypeptide vp 1 of the viruses tested (echoviruses 9 and 11, coxsackievirus b3 and poliovirus 2). in contrast, enterovirus specific immunoglobulin m antibodies of adults reacted with capsid polypeptides vp 1, vp 2, and/or vp 3 of the viruses mentioned ... | 1985 | 2999228 |
| direct inactivation of viruses by human granulocyte defensins. | human neutrophils contain a family of microbicidal peptides known as defensins. one of these defensins, human neutrophil peptide (hnp)-1, was purified, and its ability to directly inactivate several viruses was extensively tested. herpes simplex virus (hsv) types 1 and 2, cytomegalovirus, vesicular stomatitis virus, and influenza virus a/wsn were inactivated by incubation with hnp-1. two nonenveloped viruses, echovirus type 11 and reovirus type 3, were resistant to inactivation. purified homolog ... | 1986 | 3023659 |
| isolation of echovirus type 11 and enterovirus type 71 in a day care winter outbreak. | | 1987 | 3038834 |
| [nosocomial virus infections]. | enveloped viruses, e.g. influenza- or varicella viruses may cause highly contagious airborne infections. their spread is difficult to control, also in hospitals. in the case of influenza and varicella immune prophylaxis and chemotherapy/chemoprophylaxis are possible. this is of particular significance, since varicella and zoster are of increasing importance for immunocompromized patients. diarrhea is caused to a large extent by viruses. rotavirus infections play an important role in infancy, and ... | 1986 | 3107263 |
| outbreak of echovirus 11 infection in hospitalized neonates. | between july 18 and august 5, 1986, a cluster of echovirus 11 infections occurred in hospitalized neonates. ten infants were affected and one died. all cases occurring after the index case were infants who were in the nursery for at least 1 day when the index patient was also present. risk factors for secondary infection included low birth weight or gestational age and receipt of antibiotics, red blood cell transfusions, nasogastric intubation or gavage feedings. because viral infection had not ... | 1988 | 3357716 |
| congenital echovirus 11 pneumonia in association with pulmonary hypertension. | | 1988 | 3380587 |
| fatal echovirus type 7 in a premature infant. | echovirus 7 infections have not been previously recognized as fatal in neonates. a premature male member of a twin gestation developed an echovirus 7 infection at 5 days of age and succumbed to it. the clinical manifestations were similar to an echovirus 11 infection described in neonates. the second twin was free of illness as well as of virus shedding. | 1988 | 3382482 |
| successful treatment of echovirus meningoencephalitis in sex-linked agammaglobulinaemia by intrathecal and intravenous injection of high titre gammaglobulin. | a 7-year-old boy with sex-linked agammaglobulinaemia developed meningoencephalitis caused by echovirus type 11. he had convulsions, right hemiplegia, cortical motor aphasia, left abducens nerve paralysis, left hypoglossal nerve paralysis, and later became unconscious. treatment by intravenous injection of conventional gammaglobulin and intrathecal alpha-interferon brought no clinical improvement, but intrathecal administration together with intravenous injection of gammaglobulin containing a hig ... | 1987 | 3428297 |
| two concurrent epidemics of enteroviral meningitis in an obstetric neonatal unit. | a small epidemic of viral infection occurred in a neonatal unit. it involved 11 infants, all of whom recovered. echovirus 11 was the cause of illness in six infants, coxsackie b3 in four, and one infant had a biphasic illness, due first to echo 11, then to coxsackie b3. the epidemic coincided with a major outbreak of echovirus 11 and a smaller outbreak of coxsackie b3 in the community. several staff became ill. five infants were considered to have been infected by perinatal materno-infant spread ... | 1986 | 3465313 |
| perinatal echovirus infection: insights from a literature review of 61 cases of serious infection and 16 outbreaks in nurseries. | a review of literature published before june 1985 revealed 61 reported cases of neonatal echovirus infection at a nonmucosal site, including 43 cases (70%) due to echovirus 11. onset of disease occurred between the third and fifth days of life in 63% of cases, indicating that most infections are acquired in the immediate perinatal period rather than in utero. mortality was higher in infants with severe hepatitis (83%) than in infants with infection of the central nervous system (19%). acute illn ... | 1986 | 3541126 |
| competition binding studies with biotinylated echovirus 11 in cytofluorimetry analysis. | competition binding studies between viruses are usually performed with radiolabelled probes. in this report, a cytofluorimetric method using biotinylated echovirus (ev) 11 is described for the study of competition of enteroviruses for a common cell receptor site. an n-hydroxysuccinimide ester biotin spacer arm was used for biotinylation of csso4-purified ev 11. biotinylation did not change the infectivity of the virus (attachment to and replication in susceptible cells). with the exception of ev ... | 1991 | 1667786 |
| perinatal echovirus and group b coxsackievirus infections. | enteroviral infections late in pregnancy are common, especially during periods of high prevalence of community infection. most of these infections, however, are not associated with significant maternal or neonatal disease. conversely, as many as 65 per cent of women who give birth to infants with proven enteroviral infection have symptomatic disease during the perinatal period. maternal echovirus or coxsackievirus b infections are not associated with an increased risk of spontaneous abortions, b ... | 1988 | 2837356 |
| echovirus polymyositis in patients with hypogammaglobulinemia. failure of high-dose intravenous gammaglobulin therapy and review of the literature. | a 29-year-old man with x-linked hypogammaglobulinemia was treated with prednisone and methotrexate for polymyositis. subsequently, it was established that disseminated echovirus 11 infection was causing the polymyositis. treatment with large doses of intravenous gammaglobulin did not result in improvement. viral cultures of blood, urine, and cerebrospinal fluid gave positive results throughout treatment and at postmortem examination. multiple cultures of other tissues, including muscle, also gav ... | 1986 | 3728553 |
| evidence for the role of a human intestinal adenovirus in the pathogenesis of coeliac disease. | we previously noted a region of amino acid sequence homology between a-gliadin, a major alpha-gliadin component known to activate coeliac disease, and the early region e1b protein of human adenovirus serotype 12 (ad12), an adenovirus isolated from the human intestinal tract. in the present study sera from coeliac disease patients from the united kingdom and the united states were assayed for neutralising antibody to ad12 as evidence of past exposure to that virus and for antibody to synthetic pe ... | 1987 | 2822550 |
| [transient unilateral oculomotor paralysis]. | a three-year-old girl was admitted to the hospital one day after the acute onset of drooping of the left eyelid, associated with oculomotor external ophthalmoplegia. general neurological and physical examination was unremarkable. results of serological tests as well as the clinical course of the disease (spontaneous recovery) show that the unilateral oculomotor neuropathy was most likely due to a self-limited enteroviral infection. the virus could not be cultured in the csf. echovirus type 11 as ... | 1985 | 4010674 |
| isolation of echovirus type 11 from synovial fluid in acute monocytic arthritis. | | 1985 | 3966942 |
| an epidemic of acute diarrhoea in rural southern india associated with echovirus type 11 infection. | an epidemic of diarrhoea with two distinct waves affected a village of 1375 people in southern india in 1983. the first wave of the epidemic, from the last week of december 1982, had a sharp peak in january 1983 and was over by march. echovirus type 11 was isolated from patients, who also had a serum antibody response to the virus. during the second wave of the epidemic, from may to september 1983, the clinical features were different and shigella flexneri was isolated without significant viral ... | 1985 | 4067300 |
| who collaborative studies on enterovirus reference antisera. | this paper summarizes the results of co-operative studies undertaken by the who international reference centre for enteroviruses and a number of who regional reference centres for viruses, who virus collaborating laboratories, or other laboratories in a comprehensive testing programme of enterovirus equine antisera. the studies were designed to appraise the specificity of immune serum prepared in horses against five representative prototype enteroviruses (poliovirus 1, coxsackieviruses a9 and b3 ... | 1965 | 4285901 |
| fine structure of cells infected with respiratory strains of echovirus 11. | | 1967 | 4291195 |
| defectiveness of interferon production and of rubella virus interference in a line of african green monkey kidney cells (vero). | vero cells, a line of african green monkey kidney cells, failed to produce interferon when infected with newcastle disease, sendai, sindbis, and rubella viruses, although the cells were sensitive to interferon. further, infection of vero cells with rubella virus did not result in interference with the replication of echovirus 11, newcastle disease virus, or vesicular stomatitis virus, even in cultures where virtually every cell was infected with rubella virus. under the same conditions, bsc-1 ce ... | 1968 | 4302013 |
| preservation of enteroviruses by freeze-drying. | a method was developed for freeze-dry stabilization of poliovirus type 3. an ultrafiltration procedure was used to remove salts from infected tissue culture fluid, and the virus was freeze-dried after suspension in an alkaline organic buffer. this method was further tested with other picornaviruses including poliovirus types 1 and 2, coxsackieviruses a9, a20, b2, and b5, echovirus 11, and the encephalomyocarditis virus. freeze-dried preparations of the poliovirus could be shipped to distant labo ... | 1971 | 4332042 |
| echo 11 virus infection: a cause of acquired neonatal hepatitis. | | 1974 | 4417401 |
| echovirus 11 arthritis in a patient with x-linked agammaglobulinemia. | | 1987 | 3601497 |
| epidemic of echovirus 11 infections in japan in 1971. | | 1973 | 4543071 |
| fulminant hepatic failure with intractable ascites due to an echovirus 11 infection successfully managed with a peritoneo-venous (leveen) shunt. | a case is described of an infant who at 5 days of age developed an echovirus 11 infection with hepatic failure and intractable ascites, refractory to medical treatment. the ascites was successfully controlled with a peritoneo-venous (le veen) shunt inserted at 6 weeks of age. the shunt was subsequently removed when the infant was 4 months of age with no recurrence of ascites. at long-term follow-up he is growing and developing normally. this case shows that an adult le veen shunt can be successf ... | 1986 | 3723271 |
| observations on antigenic variants of echovirus type 11. | | 1966 | 4959885 |
| [fleeting paralysis after oral anti-poliomyelitic agent: rôle of echo 11 virus isolated in the patient]. | | 1969 | 5396633 |
| [epidemics of severe respiratory diseases in newborn infants caused by he echo 11 virus]. | | 1969 | 5406570 |
| [epidemic of respiratory tract diseases in newborn infants due to echo 11 virus]. | | 1970 | 5454245 |
| isolation of echovirus type 11 from two cases of burkitt's tumour and three cases of other tumours. | | 1967 | 5582280 |
| [on an epidemic outbreak of echo-11 virus infections]. | | 1967 | 5616723 |
| an epidemic of aseptic meningitis, primarily among infants, caused by echovirus 11-prime. | | 1968 | 5635489 |
| echo-11 as a respiratory virus: quantitation of infection in man. | through a series of controlled experiments in volunteers, quantitative aspects of infection, illness, and immunity to echo-11 virus were studied. echo-11 is a transmissable viral infection in man and equally infectious to the upper respiratory and the intestinal tracts. the rate of infection was directly related to the dose of virus exposure, but any infectious dose of virus produced illness in only about one-third of the infected subjects. the infectious dose for man varied over a billionfold r ... | 1968 | 5653210 |
| [diarrhea and echo 11 virus]. | | 1964 | 5900038 |
| rubella virus carrier cultures derived from congenitally infected infants. | spontaneous rubella carrier cultures derived from tissues of infants with congenital rubella were studied in an attempt to elucidate a possible mechanism for viral persistence observed in these infants. chronically infected cells were found to have a reduced growth rate and the cultures appeared to have a shortened life span. the rubella carrier state was not dependent on serum inhibitors or rubella antibodies. virtually every cell in the carrier population was found to be producing virus. the c ... | 1966 | 5938814 |
| [studies on biological characteristics of enterovirus type 70 (ev 70)]. | enterovirus type 70 (ev 70) is a new type of enterovirus, which is a causative agent of "acute hemorrhagic conjunctivitis" (ahc). it appeared for the first time in ghana in 1969, and occurred in japan in 1971. the optimal temperature for growth of ev 70 is 33-35 degrees c, and lower than that of other enteroviruses. ninety two isolates of ev 70 were investigated to know the biological characteristics. isolates were obtained in japan and foreign countries in africa, asia and europe in 1971-1981, ... | 1984 | 6090289 |
| [lesions of the vascular tract of the eye (uveitis) caused by enteroviruses in man and monkeys]. | strains of poliomyelitis, echo-11 and coxsackie a7 viruses have first been shown to produce uveitis and keratouveitis in javan macaca and green monkeys inoculated intraocularly. the most marked clinical picture of the eye affection in monkeys (keratoleukoma and opacity of the anterior chamber humor, edema and hyperemia of the iris, significant changes in the iris colour, development of posterior synechias, marked dilation of the pupil to 5-7 mm, no pupil reaction to light) was observed after ino ... | 1984 | 6093386 |
| the search for antiviral agents among corynebacteria. | extracts of strains of corynebacterium diphtheriae var. mitis avirulent, c. hofmannii, c. xerosis, c. parvum and an unidentified corynebacterium species were tested for antiviral activity against laboratory strains of echovirus type 11, adenovirus type 2 and vaccinia, and a recent isolate of herpes simplex virus. unlike a previous study, no appreciable antiviral activity was detected in the extracts tested | 1980 | 6108068 |
| echovirus 11 infection and prophylactic antiserum. | | 1982 | 6121108 |
| use of normal immunoglobulin in an echovirus 11 outbreak in a special-care baby unit. | an epidemic of echovirus 11 infections occurred in the cambridge special-care baby unit during august to october, 1982. there were 21 confirmed infections in babies; 1 died, 1 recovered after resection of a kidney, 5 had meningitis, and 6 had respiratory symptoms. normal human immunoglobulin which contained antibody to echovirus 11 was administered intramuscularly (250 mg) to give protection. none of the children given immunoglobulin immediately after delivery (205 doses) developed symptoms or i ... | 1983 | 6135922 |
| [a study of echovirus type 11 (author's transl)]. | | 1974 | 4477116 |
| a mixed epidemic associated with echovirus types 6 and 11: virologic, clinical and epidemiologic studies. | during 1979, an outbreak of mixed enterovirus infections occurred in kansas city and adjacent communities. sixty-six enteroviruses and 7 adenoviruses were recovered from 73 persons in a survey hospital population. twenty-eight persons yielded echovirus type 11, 22, echovirus type 6, and 16 either echovirus type 9 or coxsackieviruses group b, types 2 and 3. this study describes some of the clinical, virologic and epidemiologic characteristics of the outbreak. a major finding relates to the recove ... | 1981 | 6272570 |
| echovirus 11 infections of newborns with mortality during the 1979 enterovirus season in milwaukee, wis. | echovirus serotype 11 (echo-11) was implicated in three neonatal deaths during an enterovirus outbreak from july through october 1979 in milwaukee. the deaths followed congenital infections acquired in the community during late pregnancy. two of the three echo-11 and one coxsackie b4 deaths of infants occurred after cesarean section deliveries. of 225 confirmed echovirus infections, 30 to 45 percent occurred in infants under 60 days old, 54 to 67 percent in the first year of life, and 13 to 25 p ... | 1982 | 6287514 |
| [infections of the central nervous system caused by enterovirus: 223 cases seen at a pediatric hospital between 1973 and 1981]. | between 1973 and 1981, 223 patients were seen at hôpital sainte-justine in montreal for enteroviral infection of the nervous system. in 161 the cause was documented by isolation of an enterovirus from the cerebrospinal fluid (csf). the viruses most frequently isolated were echovirus 11 (36 isolates), echovirus 30 (24), coxsackievirus b2 (23), coxsackievirus b3 (19), echovirus 6 (18), coxsackievirus b5 (16), coxsackievirus a9 (15), echovirus 9 (13), echovirus 7 (12) and coxsackievirus b1 (11). as ... | 1982 | 6291736 |
| haemolytic uraemic syndrome: evidence of multiple viral infections in a cluster of ten cases. | during july 1979, ten patients were admitted to the hospital with bloody diarrhoea followed by manifestations of haemolytic uraemic syndrome (hus): acute microangiopathic haemolytic anaemia, intravascular coagulopathy, and impaired renal function. ages ranged from 13 months to 58 yr, with only two patients more than 5 yr old. in a household that included seven children born to three sisters who married three brothers, six children required hospitalization for bloody diarrhoea and four developed ... | 1983 | 6311967 |
| cross antigenicity among enteroviruses as revealed by immunoblot technique. | antigenic relationships of various human and two animal picornaviruses were investigated by the immunoblotting ("western blot") technique. the viruses included all coxsackievirus b types (1-6), poliovirus types 1-3, several strains of echovirus 11, emc virus, and fmdv. antisera included human sera and sera from rabbits hyperimmunized with either purified picornaviruses, viral structural polypeptides (vp8), boiled or "sample-boiled" virions. group-specific reactions of various extent were observe ... | 1983 | 6312682 |
| dissimilar manifestations of intrauterine infection with echovirus 11 in premature twins. | echoviruses cause neonatal disease following intrauterine and intrapartum acquisition of the organism or by nosocomial infection. dizygous twins apparently became infected following transplacental transmission of echovirus 11. at 5 days of age, both twins experienced poor feeding, lethargy and hypothermia, and evidence of coagulopathy and hepatitis. during the sixth week of illness, the convalescence of twin a was complicated by peritonitis and sepsis, and the infant died. pathologic findings in ... | 1983 | 6344839 |
| [nosocomial dyspepsia in newborn and young infants. a 15-month prospective study with continuous rotavirus surveillance]. | a 15 months prospective study of gastroenteritis in hospitalized newborns and infants (n = 201) was combined with a rotavirus infection surveillance. stool specimens were investigated weekly (cft). from patients with gastroenteritis (n = 320) an infectious agent could be detected on average in 41% of each patient group: rotavirus n = 54, staph. aureus n = 22, toxin producing e. coli n = 4, other bacteria n = 25, candida albicans n = 17, echovirus 11 n = 1. with certain exceptions, the pathogens ... | 1983 | 6353207 |
| [echovirus 11 outbreak among premature newborn infants in a neonatal intensive care unit]. | during a period of 3 weeks, 17 premature neonates 4 of them weighing less than 1000 g at birth became infected with echovirus 11 in a neonatal intensive-care unit. beside 3 inapparent infections, severe 'septicaemic' illness was observed among 5 premature neonates combined with meningitis and apnoeic attacks. 4 neonates presented meningitis as the predominant clinical feature and 3 showed gastrointestinal symptoms without neurological involvement. 2 children experienced a febrile illness with ap ... | 1985 | 4013560 |
| echovirus type 11 infection in singapore. | | 1984 | 6463661 |
| echo 11 virus outbreak in a nursery associated with myocarditis. | | 1973 | 4718801 |
| echovirus 11 infections in south dakota, 1979-1980: spectrum of disease. | | 1983 | 6575443 |
| disseminated neonatal echovirus 11 disease following antenatal maternal infection with a virus-positive cervix and virus-negative gastrointestinal tract. | an infant girl was born apparently well one week after her mother had had a mild illness with chills, fever, and diarrhea. on the third day of life, the infant became ill and died four days later with necrotizing hepatitis. on the same day, echovirus type 11 was recovered from the throat, rectum, and buffy coat of the infant and from the cervix of the mother. at this time, the mother had an igm neutralizing antibody titer to echovirus type 11 and 1:128, but no igg antibodies. the infant had no e ... | 1983 | 6619813 |
| epidemic of meningitis and febrile illness in neonates caused by echo type 11 virus in philadelphia. | between april and november, 1980, an outbreak of meningitis and of febrile illness of neonates caused by echo 11 virus occurred in philadelphia and surrounding communities. thirty-eight virologically confirmed and ten virologically presumptive cases of meningitis were hospitalized in two philadelphia hospitals for children. most patients had fever and irritability. vomiting, upper respiratory symptoms and poor feeding were present in one-third to one-half of the cases. seventy-five percent of ca ... | 1983 | 6634464 |
| subacute salicylate intoxication in an infant with echovirus type 11 infection. | an antigenic variant of e 11 was the most frequently encountered echovirus in the united states in 1979. several reports have indicated that infection with this agent was often associated with an overwhelming clinical course in neonates. our case was in a 5-week-old infant with an e 11 infection complicated by subacute salicylate intoxication. this unfavorable combination resulted in a fulminant and fatal illness simulating reye's syndrome. | 1984 | 6701596 |
| echovirus type 11 infection in neonates in fiji. | | 1984 | 6727760 |
| isolation and characterization of non-haemagglutinating echoviorus 11. | after multiplication in the continuous human cell lines hela, kb, and hep 2, echovirus 11 (prototype strain gregory) loses its haemagglutinating (ha) activity but retains infectivity. after seven passages in hela cells the ha activity was not restored. there was no correlation between the loss of ha activity and modification of thermosensitivity, plaque morphology, surface properties and antigenicity. ha- echovirus 11 particles did not show the properties of defective interfering (di) particles ... | 1980 | 6780657 |
| fulminant neonatal hepatic necrosis associated with echovirus type 11 infection. | | 1983 | 6837030 |
| inability of counterimmunoelectrophoresis to detect echovirus in cerebrospinal fluid. | methods for rapid detection of viral antigens in cerebrospinal fluid (csf) are needed to aid in the differentiation of viral from bacterial meningitis. the formation of precipitin bands in patients with suspect viral meningitis utilizing viral antisera in a counterimmunoelectrophoresis (cie) system has been described. to investigate further the possible value of cie in the diagnosis of viral meningitis, the specificity of the csf precipitin bands was studied. precipitin bands were formed between ... | 1983 | 6881103 |
| postmortem manifestations of echovirus 11 sepsis in five newborn infants. | five cases of fatal neonatal echovirus type 11 infection were observed in the boston area during the summer and fall of 1979. four of the mothers experienced gastroenteritis with fever and abdominal cramps late in the third trimester of pregnancy. the clinical course of each case was characterized by jaundice, hepatosplenomegaly, and progressive hepatic failure; all five infants were severely hypotonic. at autopsy massive hepatic and adrenal hemorrhage and necrosis, with evidence of consumption ... | 1983 | 6885039 |
| epidemiology of an outbreak in a maternity unit of infections with an antigenic variant of echovirus 11. | after an 8-day-old child had died with clinical signs of septicemia, 6 other newborns fell ill. virus was isolated from various sites from all the 6 children (28 isolations). the agent was identified by cross neutralization tests as an antigenic variant of echovirus 11. the agent could not be isolated from mothers or nursery staff (49 people). we therefore tried to trace the path of infection by isolating specific igm and igg antibodies. a laboratory infection by the agent isolated enabled the t ... | 1982 | 7069410 |
| echovirus 11 dense particles: isolation and preliminary characterization. | dense particles (density 1.44 g/ml) were isolated during purification in cscl of echovirus 11 produced in hela cells. the dense particles had similar antigenic properties and similar rna and protein composition to standard (density 1.33 g/ml) echovirus 11 particles. they differed from standard particles in their higher buoyant density, lower infectivity and slightly smaller diameter. in contrast to other picornavirus dense particles, echovirus 11 dense particles were present as a major component ... | 1982 | 7097249 |
| immunoglobulin responses to echovirus type 11 by enzyme linked immunosorbent assay: single-serum diagnosis of acute infection by specific igm antibody. | an indirect solid-phase enzyme-linked immunosorbent assay (elisa) for the determination of specific igm and igg antibodies to echovirus type 11 in a single dilution of serum was developed using partially purified echovirus type 11 bound to microplates. whole serum was used for igg antibody but prior to assaying for igm antibody interfering igg was removed by ion exchange chromatography. the elisa for echovirus type 11 igg antibody was a more sensitive, rapid, technically easier and less costly a ... | 1984 | 6394604 |
| reaction pattern of immunoglobulin m and g antibodies to echovirus 11 structural proteins. | the immunoglobulin m and g specific immune response of humans to echovirus 11 proteins during an echovirus 11 outbreak was studied by the immunoblot technique. whereas immunoglobulin g antibodies were directed most exclusively to the vp 1 protein, the immunoglobulin m antibodies were directed against vp 1, vp 2, and vp 3. | 1984 | 6470099 |
| fatal infection with echovirus 11. | twenty-four fatal cases of echo 11 infection in the eleven years 1968-78 are presented. all were children, and could be divided into two groups according to age at death and clinical presentation. the first group comprised 12 babies who died aged between 5 and 11 days after a short illness characterised by collapse, acidosis, and bleeding. at necropsy there was evidence of disseminated intravascular coagulation with haemorrhage into many organs including the renal medulla, suprarenal glands, gas ... | 1982 | 7199896 |
| echovirus type 11 infection. | | 1981 | 7253711 |